Habituation is a form of non-associative learning in which an organism’s non-reinforced response to a stimulus decreases after repeated or prolonged presentations of that stimulus . For example, organisms may habituate to repeated sudden loud noises when they learn that these have no consequences.
150-466: Anandamide (ANA) , also referred to as N -arachidonoylethanolamine (AEA) is a fatty acid neurotransmitter belonging to the fatty acid derivative group known as N-Acylethanolamine (NAE). Anandamide takes its name from the Sanskrit word ananda , meaning "joy, bliss, delight," plus amide . Anandamide, the first discovered endocannabinoid , engages with the body's endocannabinoid system by binding to
300-596: A hydrogen bond facilitates their interaction. Following this, anandamide is drawn towards the membrane interior, where it forms a molecular complex with cholesterol. This process involves a conformational adaptation of anandamide to the apolar membrane environment. Subsequently, the anandamide-cholesterol complex is directed to the cannabinoid receptor (CB1) and then exits. Sanskrit Sanskrit ( / ˈ s æ n s k r ɪ t / ; attributively 𑀲𑀁𑀲𑁆𑀓𑀾𑀢𑀁 , संस्कृत- , saṃskṛta- ; nominally संस्कृतम् , saṃskṛtam , IPA: [ˈsɐ̃skr̩tɐm] )
450-429: A characteristic of life as DNA ." Functionally, habituation is thought to free up cognitive resources for other stimuli that are associated with biologically important events by diminishing the response to inconsequential stimuli. A progressive decline of a behavior in a habituation procedure may also reflect nonspecific effects such as fatigue , which must be ruled out when the interest is in habituation. Habituation
600-581: A dead language in the most common usage of the term. Pollock's notion of the "death of Sanskrit" remains in this unclear realm between academia and public opinion when he says that "most observers would agree that, in some crucial way, Sanskrit is dead." Habituation Habituation can occur in responses that habituate include those that involve an entire organism or specific biological component systems of an organism. The broad ubiquity of habituation across all forms of life has led to it being called "the simplest, most universal form of learning...as fundamental
750-433: A focus on Indian philosophies and Sanskrit. Though written in a number of different scripts, the dominant language of Hindu texts has been Sanskrit. It or a hybrid form of Sanskrit became the preferred language of Mahayana Buddhism scholarship; for example, one of the early and influential Buddhist philosophers, Nagarjuna (~200 CE), used Classical Sanskrit as the language for his texts. According to Renou, Sanskrit had
900-447: A habituation process and a sensitization process. The dual-process theory argues that all noticeable stimuli will elicit both of these processes and that the behavioral output will reflect a summation of both processes. The habituation process is decremental, whereas the sensitization process is incremental enhancing the tendency to respond. Thus when the habituation process exceeds the sensitization process behavior shows habituation, but if
1050-591: A language competed with numerous, less exact vernacular Indian languages called Prakritic languages ( prākṛta - ). The term prakrta literally means "original, natural, normal, artless", states Franklin Southworth . The relationship between Prakrit and Sanskrit is found in Indian texts dated to the 1st millennium CE. Patañjali acknowledged that Prakrit is the first language, one instinctively adopted by every child with all its imperfections and later leads to
1200-471: A level lower than normal and eventually returns to neutral. This pattern coincides with two internal processes referred to as the a-process and b-process. Hence, the opponent-process theory predicts that subjects will show no reaction following a stimulus after a repetition of this same stimulus. It is the after-reaction that is much larger and prolonged than if an initial reaction to a stimulus occurred. Habituation abnormalities have been repeatedly observed in
1350-658: A limited role in the Theravada tradition (formerly known as the Hinayana) but the Prakrit works that have survived are of doubtful authenticity. Some of the canonical fragments of the early Buddhist traditions, discovered in the 20th century, suggest the early Buddhist traditions used an imperfect and reasonably good Sanskrit, sometimes with a Pali syntax, states Renou. The Mahāsāṃghika and Mahavastu, in their late Hinayana forms, used hybrid Sanskrit for their literature. Sanskrit
1500-416: A meal increases the amount that is consumed in a meal, most likely because habituation is stimulus-specific and because variety may introduce dishabituation effects. Food variety also slows the rate of habituation in children and may be an important contributing factor to the recent increases in obesity. Richard Solomon and John Corbit (1974) proposed the opponent-process theory , arguing that habituation
1650-454: A natural part of the earliest Vedic language, and that these developed in the centuries after the composition had been completed, and as a gradual unconscious process during the oral transmission by generations of reciters. The primary source for this argument is internal evidence of the text which betrays an instability of the phenomenon of retroflexion, with the same phrases having sandhi-induced retroflexion in some parts but not other. This
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#17327803365801800-479: A negative evidence to Pollock's hypothesis, but it is not positive evidence. A closer look at Sanskrit in the Indian history after the 12th century suggests that Sanskrit survived despite the odds. According to Hanneder, On a more public level the statement that Sanskrit is a dead language is misleading, for Sanskrit is quite obviously not as dead as other dead languages and the fact that it is spoken, written and read will probably convince most people that it cannot be
1950-420: A new or changing stimulus. Orienting responses can result in overt, observable behaviors as well as psychophysiological responses such as EEG activity and undergo habituation with repeated presentation of the eliciting stimulus. The Sokolov model assumes that when a stimulus is experienced several times, the nervous system creates a model of the expected stimulus (a stimulus model). With additional presentations of
2100-546: A pan-Indo-Aryan accessibility to information and knowledge in the ancient and medieval times, in contrast to the Prakrit languages which were understood just regionally. It created a cultural bond across the subcontinent. As local languages and dialects evolved and diversified, Sanskrit served as the common language. It connected scholars from distant parts of South Asia such as Tamil Nadu and Kashmir, states Deshpande, as well as those from different fields of studies, though there must have been differences in its pronunciation given
2250-520: A pig brain and canine gut, they were able to isolate ANA using mass spectrometry and nuclear magnetic resonance spectroscopy . ANA works within the system of the brain associated with the feeling of reward, and as such, has been the topic of many research studies. Since the 1992 findings, many studies have been completed to examine ANA further, including research on behavioral and molecular effects. According to in vitro research, anandamide effects are mediated primarily by CB 1 cannabinoid receptors in
2400-467: A potent agonist at the TRPV1 vanilloid receptor, a weak agonist at both CB 1 and CB 2 receptors, and an inhibitor of anandamide reuptake. Consequently, anandamide levels in the body and brain are elevated. Thus, paracetamol acts as a pro-drug for a cannabimimetic metabolite, which may be partially or fully responsible for its analgesic effects. Black pepper contains the alkaloid guineesine , which
2550-402: A pre-existing (innate) responses and often are shown to depend on peripheral (non-cerebral) synaptic changes in the sensory-motor pathway. Most modern learning theorists, however, consider any behavioral change that occurs as a result of experience to be learning, so long as it cannot be accounted for by motor fatigue, sensory adaptation, developmental changes or damage. Criteria for verifying
2700-578: A refined and standardized grammatical form that emerged in the mid-1st millennium BCE and was codified in the most comprehensive of ancient grammars, the Aṣṭādhyāyī ('Eight chapters') of Pāṇini . The greatest dramatist in Sanskrit, Kālidāsa , wrote in classical Sanskrit, and the foundations of modern arithmetic were first described in classical Sanskrit. The two major Sanskrit epics, the Mahābhārata and
2850-556: A response to the presence of the researchers. In another study, Mitumba chimpanzees in the Gombe National Park were habituated for at least four years before the introduction of systematic data collection. Researchers also use habituation and dishabituation procedures in the laboratory to study the perceptual and cognitive capabilities of human infants. The presentation of a visual stimulus to an infant elicits looking behavior that habituates with repeated presentations of
3000-417: A response-decline as learning Importantly, systematic response-declines can be produced by non-learning factors such as sensory adaptation (obstruction of stimulus detection), motor fatigue, or damage. Three diagnostic criteria are used to distinguish response-declines produced by these non-learning factors and response-declines produced by habituation (learning) processes. These are: Early studies relied on
3150-538: A restrained language from which archaisms and unnecessary formal alternatives were excluded". The Classical form of the language simplified the sandhi rules but retained various aspects of the Vedic language, while adding rigor and flexibilities, so that it had sufficient means to express thoughts as well as being "capable of responding to the future increasing demands of an infinitely diversified literature", according to Renou. Pāṇini included numerous "optional rules" beyond
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#17327803365803300-432: A result of the introduction of a different stimulus can decrease after repeated presentation of the "dishabituating" stimulus. Some habituation procedures appear to result in a habituation process that last days or weeks. This is considered long-term habituation. It persists over long durations of time (i.e., shows little or no spontaneous recovery). Long-term habituation can be distinguished from short-term habituation which
3450-439: A similar phonetic structure to Tamil. Hock et al. quoting George Hart state that there was influence of Old Tamil on Sanskrit. Hart compared Old Tamil and Classical Sanskrit to arrive at a conclusion that there was a common language from which these features both derived – "that both Tamil and Sanskrit derived their shared conventions, metres, and techniques from a common source, for it is clear that neither borrowed directly from
3600-402: A social learning deficit in individuals with an extremely inhibited temperament, which is a possible mechanism for a higher risk of social anxiety. Although habituation has been regarded as a learning process by some as early as 1887, its learning status remained controversial up until the 1920s - 1930s. While conceding that reflexes may "relax" or otherwise decrease with repeated stimulation,
3750-460: A study on aggression in female chimpanzees from a group known as the " Kasakela Chimpanzee Community ", researchers habituated the chimpanzees by repeatedly exposing them to the presence of human beings. Their efforts to habituate the chimpanzees before the field researchers studied the animal's behavior was necessary in order for them to eventually be able to note the natural behavior of the chimpanzees, instead of simply noting chimpanzee behavior as
3900-442: A variety of neuropsychiatric conditions including autism spectrum disorder (ASD), fragile X syndrome , schizophrenia , Parkinson's disease (PD), Huntington's disease (HD), attention deficit hyperactivity disorder (ADHD), Tourette's syndrome (TS), and migraine . In human clinical studies, habituation is most often studied using the acoustic startle reflex ; acoustic tones are delivered to participants through headphones and
4050-451: Is spontaneous recovery . That is, a habituated response to a stimulus recovers (increases in magnitude) when a significant amount of time (hours, days, weeks) passes between stimulus presentations. "Potentiation of habituation" is observed when tests of spontaneous recovery are given repeatedly. In this phenomenon, the decrease in responding that follows spontaneous recovery becomes more rapid with each test of spontaneous recovery. Also noted
4200-711: Is a classical language belonging to the Indo-Aryan branch of the Indo-European languages . It arose in South Asia after its predecessor languages had diffused there from the northwest in the late Bronze Age . Sanskrit is the sacred language of Hinduism , the language of classical Hindu philosophy , and of historical texts of Buddhism and Jainism . It was a link language in ancient and medieval South Asia, and upon transmission of Hindu and Buddhist culture to Southeast Asia, East Asia and Central Asia in
4350-411: Is able to detect the stimulus but can no longer respond efficiently. Stimulus-specificity stipulates that the response-decline is not general (due to motor fatigue) but occurs only to the original stimulus that was repeated. If a response-decline shows 1) dishabituation, 2) spontaneous recovery that is inversely correlated with the extent of decline, and/or 3) stimulus-specificity, then habituation learning
4500-516: Is akin to that of Latin and Ancient Greek in Europe. Sanskrit has significantly influenced most modern languages of the Indian subcontinent , particularly the languages of the northern, western, central and eastern Indian subcontinent. Sanskrit declined starting about and after the 13th century. This coincides with the beginning of Islamic invasions of South Asia to create, and thereafter expand
4650-413: Is also found in emotional responses. This theory proposes that not all emotional reactions to a stimulus change in the same way when the stimulus is presented repeatedly: some weaken (decrease) while others are strengthened (increase). The overall effect is that an outside stimulus provokes an emotional reaction that increases rapidly until it is at its most intense. Gradually, the emotional state declines to
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4800-432: Is an anandamide reuptake inhibitor. It may therefore increase anandamide's physiological effects. Endocannabinoid transporters for anandamide and 2-arachidonoylglycerol include the heat shock proteins ( Hsp70s ) and fatty acid binding proteins (FABPs). Anandamide shows a preference for binding to cholesterol and ceramide over other membrane lipids. Cholesterol acts as a binding partner for anandamide. Initially,
4950-436: Is degraded primarily by the fatty acid amide hydrolase (FAAH) enzyme, which converts anandamide into ethanolamine and arachidonic acid. As such, inhibitors of FAAH lead to elevated anandamide levels and are being pursued for possible therapeutic use. Anandamide was discovered by Raphael Mechoulam and fellow coworkers in 1992. This was the first marijuana-like substance produced by the human body to be observed. By examining
5100-452: Is found in the writing of Bharata Muni , the author of the ancient Natya Shastra text. The early Jain scholar Namisādhu acknowledged the difference, but disagreed that the Prakrit language was a corruption of Sanskrit. Namisādhu stated that the Prakrit language was the pūrvam ('came before, origin') and that it came naturally to children, while Sanskrit was a refinement of Prakrit through "purification by grammar". Sanskrit belongs to
5250-542: Is generated from membrane N -acylphosphatidylethanolamines (NAPEs), and reveals that bile acids – which are mainly involved in the absorption of lipids in the small intestine – modulate its biogenesis. Endogenous anandamide is present at very low levels and has a very short half-life due to the action of the enzyme fatty acid amide hydrolase (FAAH), which breaks it down into free arachidonic acid and ethanolamine . Studies of piglets show that dietary levels of arachidonic acid and other essential fatty acids affect
5400-525: Is identified by the nine characteristics listed above. The changes in synaptic transmission that occur during habituation have been well-characterized in the Aplysia gill and siphon withdrawal reflex. Habituation has been shown in essentially every species of animal and at least, in one species of plants (Mimosa pudica), in isolated neuronally-differentiated cell-lines, as well as in quantum perovskite. The experimental investigation of simple organisms such as
5550-428: Is inhibited causing habituation. However, if the stimulus is changed so that it no longer matches the stimulus model, the orienting response is no longer inhibited. Sokolov locates the stimulus model in the cerebral cortex. The Groves and Thompson dual-process theory of habituation posits that two separate processes exist in the central nervous system that interacts to produce habituation. The two distinct processes are
5700-450: Is not perceived as a direct measure for mental processes as well. In previous theories of habituation, an infant's dishabituation was thought to represent their own realization of the remembered stimulus of stimuli. For example: if infants would be dishabituated to a certain color item to a new item, it would be noticed that they remembered the color and compared the two colors for differences. Also, another challenge that comes with habituation
5850-552: Is not to be confused with true habituation to drugs, wherein repeated doses have an increasingly diminished effect, as is often seen in addicts or persons taking painkillers frequently. Habituation as a form of non- associative learning can be distinguished from other behavioral changes (e.g., sensory/ neural adaptation , fatigue) by considering the characteristics of habituation that have been identified over several decades of research. The characteristics first described by Thompson and Spencer were updated in 2008 and 2009, to include
6000-557: Is often predictive of symptom severity in several neuropsychiatric disorders, including ASD, PD, and HD. Moreover, there are instances where treatments that normalise the habituation-deficit also improve other associated symptoms. As a therapy, habituation processes have been hypothesized to underlie the efficacy of behavioural therapies (i.e. habit reversal training , exposure therapy ) for TS and PTSD , although extinction processes may be operating instead. Habituation procedures are used by researchers for many reasons. For example, in
6150-562: Is one of the most-studied areas of the brain in relation to habituation. A common approach is to observe the visual processing of facial expressions. A study by Breiter and colleagues used fMRI scans to identify which areas of the brain habituate and at what rate. Their results showed that the human amygdala responds and rapidly habituates preferentially to fearful facial expressions over neutral ones. They also observed significant amygdala signal changes in response to happy faces over neutral faces. Blackford, Allen, Cowan, and Avery (2012) compared
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6300-416: Is provided by a study with harbor seals . In one study researchers measured the responses of harbor seals to underwater calls of different types of killer whales . The seals showed a strong response when they heard the calls of mammal-eating killer whales. However, they did not respond strongly when hearing familiar calls of the local fish-eating population. The seals, therefore, are capable of habituating to
6450-532: Is rare in the later version of the language. The Homerian Greek, like Ṛg-vedic Sanskrit, deploys simile extensively, but they are structurally very different. The early Vedic form of the Sanskrit language was far less homogenous compared to the Classical Sanskrit as defined by grammarians by about the mid-1st millennium BCE. According to Richard Gombrich—an Indologist and a scholar of Sanskrit, Pāli and Buddhist Studies—the archaic Vedic Sanskrit found in
6600-441: Is relevant in psychiatry and psychopathology , as several neuropsychiatric conditions including autism , schizophrenia , migraine , and Tourette syndrome show reduced habituation to a variety of stimulus-types both simple and complex. There is an additional connotation to the term habituation which applies to psychological dependency on drugs , and is included in several online dictionaries . A team of specialists from
6750-429: Is sensitive to spontaneous recovery, showing recovery that is inversely correlated with the amount of response-decline. This is the opposite of what would be expected if sensory adaptation or motor fatigue were the cause of the response-decline. Sensory adaptation (or neural adaptation ) occurs when an organism can no longer detect the stimulus as efficiently as when first presented and motor fatigue occurs when an organism
6900-564: Is supported. Despite the ubiquity of habituation and its modern acceptance as a genuine form of learning it has not enjoyed the same focus within research as other forms of learning. On this topic, the animal psychologist James McConnell said "...nobody cares…much about habituation"). It has been suggested that the apathy held towards habituation is due to 1) resistance from traditional learning theorists maintain memory requires reproduction of propositional/linguistic content; 2) resistance from behaviorists who maintain that "true" learning requires
7050-479: Is taken along with evidence of controversy, for example, in passages of the Aitareya-Āraṇyaka (700 BCE), which features a discussion on whether retroflexion is valid in particular cases. The Ṛg-veda is a collection of books, created by multiple authors. These authors represented different generations, and the mandalas 2 to 7 are the oldest while the mandalas 1 and 10 are relatively the youngest. Yet,
7200-499: Is the changing response to food as it is repeatedly experienced during a meal. When people eat the same food during a meal, they begin to respond less to the food as they become habituated to the motivating properties of the food and decrease their consumption. Eating less during a meal is usually interpreted as reaching satiety or "getting full", but experiments suggest that habituation also plays an important role. Many experiments with animals and humans have shown that providing variety in
7350-529: Is the dichotomy of novelty vs familiar stimuli. If an infant preferred a novel still, this meant the infant observed the new spatial relation of the object, but not the object itself. If an infant preferred familiarity, the infant would notice the pattern of the stimuli, instead of the actual new stimuli. The habituation/dishabituation procedure is also used to discover the resolution of perceptual systems. For instance, by habituating someone to one stimulus, and then observing responses to similar ones, one can detect
7500-413: Is the importance of defensive responses to the sudden appearance of any new, unfamiliar stimulus, whether it is dangerous or not. An initial defensive response to a new stimulus is important because if an animal fails to respond to a potentially dangerous unknown stimulus, the results could be deadly. Despite this initial, innate defensive response to an unfamiliar stimulus, the response becomes habituated if
7650-589: Is the predominant language of one of the largest collection of historic manuscripts. The earliest known inscriptions in Sanskrit are from the 1st century BCE, such as the Ayodhya Inscription of Dhana and Ghosundi-Hathibada (Chittorgarh) . Though developed and nurtured by scholars of orthodox schools of Hinduism, Sanskrit has been the language for some of the key literary works and theology of heterodox schools of Indian philosophies such as Buddhism and Jainism. The structure and capabilities of
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#17327803365807800-540: The Bhagavata Purana , the Panchatantra and many other texts are all in the Sanskrit language. The Classical Sanskrit with its exacting grammar was thus the language of the Indian scholars and the educated classes, while others communicated with approximate or ungrammatical variants of it as well as other natural Indian languages. Sanskrit, as the learned language of Ancient India, thus existed alongside
7950-580: The Dalai Lama , the Sanskrit language is a parent language that is at the foundation of many modern languages of India and the one that promoted Indian thought to other distant countries. In Tibetan Buddhism, states the Dalai Lama, Sanskrit language has been a revered one and called legjar lhai-ka or "elegant language of the gods". It has been the means of transmitting the "profound wisdom of Buddhist philosophy" to Tibet. The Sanskrit language created
8100-613: The Indo-European family of languages . It is one of the three earliest ancient documented languages that arose from a common root language now referred to as Proto-Indo-European : Other Indo-European languages distantly related to Sanskrit include archaic and Classical Latin ( c. 600 BCE–100 CE, Italic languages ), Gothic (archaic Germanic language , c. 350 CE ), Old Norse ( c. 200 CE and after), Old Avestan ( c. late 2nd millennium BCE ) and Younger Avestan ( c. 900 BCE). The closest ancient relatives of Vedic Sanskrit in
8250-753: The Rigveda had already evolved in the Vedic period, as evidenced in the later Vedic literature. Gombrich posits that the language in the early Upanishads of Hinduism and the late Vedic literature approaches Classical Sanskrit, while the archaic Vedic Sanskrit had by the Buddha 's time become unintelligible to all except ancient Indian sages. The formalization of the Saṃskṛta language is credited to Pāṇini , along with Patañjali's Mahābhāṣya and Katyayana's commentary that preceded Patañjali's work. Panini composed Aṣṭādhyāyī ('Eight-Chapter Grammar'), which became
8400-532: The Rigveda , a collection of 1,028 hymns composed between 1500 BCE and 1200 BCE by Indo-Aryan tribes migrating east from the mountains of what is today northern Afghanistan across northern Pakistan and into northwestern India. Vedic Sanskrit interacted with the preexisting ancient languages of the subcontinent, absorbing names of newly encountered plants and animals; in addition, the ancient Dravidian languages influenced Sanskrit's phonology and syntax. Sanskrit can also more narrowly refer to Classical Sanskrit ,
8550-531: The Rāmāyaṇa , however, were composed in a range of oral storytelling registers called Epic Sanskrit which was used in northern India between 400 BCE and 300 CE, and roughly contemporary with classical Sanskrit. In the following centuries, Sanskrit became tradition-bound, stopped being learned as a first language, and ultimately stopped developing as a living language. The hymns of the Rigveda are notably similar to
8700-602: The World Health Organization assembled in 1957 to address the problem of drug addiction and adopted the term "drug habituation" to distinguish some drug-use behaviors from drug addiction. According to the WHO lexicon of alcohol and drug terms, habituation is defined as "becoming accustomed to any behavior or condition, including psychoactive substance use". By 1964, the report of the Surgeon General of
8850-415: The amoeba and Stentor coeruleus to sea slugs to humans. Habituation processes are adaptive, allowing animals to adjust their innate behaviors to changes in their natural world. A natural animal instinct, for example, is to protect themselves and their territory from any danger and potential predators. An animal needs to respond quickly to the sudden appearance of a predator. What may be less obvious
9000-406: The sandhi rules, both internal and external. Quite many words found in the early Vedic Sanskrit language are never found in late Vedic Sanskrit or Classical Sanskrit literature, while some words have different and new meanings in Classical Sanskrit when contextually compared to the early Vedic Sanskrit literature. Arthur Macdonell was among the early colonial era scholars who summarized some of
9150-500: The verbal adjective sáṃskṛta- is a compound word consisting of sáṃ ('together, good, well, perfected') and kṛta - ('made, formed, work'). It connotes a work that has been "well prepared, pure and perfect, polished, sacred". According to Biderman, the perfection contextually being referred to in the etymological origins of the word is its tonal—rather than semantic—qualities. Sound and oral transmission were highly valued qualities in ancient India, and its sages refined
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#17327803365809300-455: The "invariance doctrine" stipulated that reflexes should not remain constant and that variable reflexes were a pathological manifestation. Indeed, air pilots who showed habituation of post-rotational nystagmus reflex were sometimes ejected from or not recruited for service for World War I: on the grounds that a variable reflex response indicated either a defective vestibular apparatus or a lack of vigilance. Eventually, however, more research from
9450-414: The 13th century, a premier center of Sanskrit literary creativity, Sanskrit literature there disappeared, perhaps in the "fires that periodically engulfed the capital of Kashmir" or the "Mongol invasion of 1320" states Pollock. The Sanskrit literature which was once widely disseminated out of the northwest regions of the subcontinent, stopped after the 12th century. As Hindu kingdoms fell in the eastern and
9600-532: The 7th century where he established a major center of learning and language translation under the patronage of Emperor Taizong. By the early 1st millennium CE, Sanskrit had spread Buddhist and Hindu ideas to Southeast Asia, parts of the East Asia and the Central Asia. It was accepted as a language of high culture and the preferred language by some of the local ruling elites in these regions. According to
9750-529: The CB1/CB2 may affect neurotransmission of dopamine, serotonin, GABA, and glutamate. Endocannabinoids may disturb homeostasis in several ways: by enhancing hunger sensations , encouraging increased food intake , and shifting energy balance towards energy storage . A resultant decrease in energy expenditure is observed. Cortical glutamatergic transmission may be modulated by endocannabinoids during stress and fear habituation . Blockade of CB1 receptors
9900-425: The Classical Sanskrit language launched ancient Indian speculations about "the nature and function of language", what is the relationship between words and their meanings in the context of a community of speakers, whether this relationship is objective or subjective, discovered or is created, how individuals learn and relate to the world around them through language, and about the limits of language? They speculated on
10050-532: The Dravidian languages borrowed from Sanskrit vocabulary, but they have also affected Sanskrit on deeper levels of structure, "for instance in the domain of phonology where Indo-Aryan retroflexes have been attributed to Dravidian influence". Similarly, Ferenc Ruzca states that all the major shifts in Indo-Aryan phonetics over two millennia can be attributed to the constant influence of a Dravidian language with
10200-521: The Dravidian words and forms, without modifying the word order; but the same thing is not possible in rendering a Persian or English sentence into a non-Indo-Aryan language. Shulman mentions that "Dravidian nonfinite verbal forms (called vinaiyeccam in Tamil) shaped the usage of the Sanskrit nonfinite verbs (originally derived from inflected forms of action nouns in Vedic). This particularly salient case of
10350-556: The Groves and Thompson dual-process theory, and the SOP (Standard Operating Procedures/Sometimes Opponent Process) model formulated by Allan Wagner The stimulus-model comparator theory emerged from the research of Sokolov who used the orienting response as the cornerstone of his studies, and operationally defining the orienting response as EEG activity. Orienting responses are heightened sensitivity experienced by an organism when exposed to
10500-476: The Indo-Aryan language underwent rapid linguistic change and morphed into the Vedic Sanskrit language. The pre-Classical form of Sanskrit is known as Vedic Sanskrit . The earliest attested Sanskrit text is the Rigveda , a Hindu scripture from the mid- to late-second millennium BCE. No written records from such an early period survive, if any ever existed, but scholars are generally confident that
10650-519: The Indo-European languages are the Nuristani languages found in the remote Hindu Kush region of northeastern Afghanistan and northwestern Himalayas, as well as the extinct Avestan and Old Persian – both are Iranian languages . Sanskrit belongs to the satem group of the Indo-European languages. Colonial era scholars familiar with Latin and Greek were struck by the resemblance of
10800-532: The Muslim rule in the form of Sultanates, and later the Mughal Empire . Sheldon Pollock characterises the decline of Sanskrit as a long-term "cultural, social, and political change". He dismisses the idea that Sanskrit declined due to "struggle with barbarous invaders", and emphasises factors such as the increasing attractiveness of vernacular language for literary expression. With the fall of Kashmir around
10950-496: The Muslim rulers. Hindu rulers such as Shivaji of the Maratha Empire , reversed the process, by re-adopting Sanskrit and re-asserting their socio-linguistic identity. After Islamic rule disintegrated in South Asia and the colonial rule era began, Sanskrit re-emerged but in the form of a "ghostly existence" in regions such as Bengal. This decline was the result of "political institutions and civic ethos" that did not support
11100-499: The Saṃskṛta language, both in its vocabulary and grammar, to the classical languages of Europe. In The Oxford Introduction to Proto-Indo-European and the Proto-Indo-European World , Mallory and Adams illustrate the resemblance with the following examples of cognate forms (with the addition of Old English for further comparison): The correspondences suggest some common root, and historical links between some of
11250-638: The South India, such as the great Vijayanagara Empire , so did Sanskrit. There were exceptions and short periods of imperial support for Sanskrit, mostly concentrated during the reign of the tolerant Mughal emperor Akbar . Muslim rulers patronized the Middle Eastern language and scripts found in Persia and Arabia, and the Indians linguistically adapted to this Persianization to gain employment with
11400-535: The United States on smoking and health included four features that characterize drug habituation according to WHO: 1) "a desire (but not a compulsion) to continue taking the drug for the sense of improved well-being which it engenders"; 2) "little or no tendency to increase the dose"; 3) "some degree of psychic dependence on the effect of the drug, but absence of physical dependence and hence of an abstinence syndrome"; 4) "detrimental effects, if any, primarily on
11550-447: The Vedic Sanskrit in these books of the Ṛg-veda "hardly presents any dialectical diversity", states Louis Renou – an Indologist known for his scholarship of the Sanskrit literature and the Ṛg-veda in particular. According to Renou, this implies that the Vedic Sanskrit language had a "set linguistic pattern" by the second half of the 2nd millennium BCE. Beyond the Ṛg-veda, the ancient literature in Vedic Sanskrit that has survived into
11700-451: The Vedic Sanskrit's bahulam framework, to respect liberty and creativity so that individual writers separated by geography or time would have the choice to express facts and their views in their own way, where tradition followed competitive forms of the Sanskrit language. The phonetic differences between Vedic Sanskrit and Classical Sanskrit, as discerned from the current state of the surviving literature, are negligible when compared to
11850-459: The alphabet, the structure of words, and its exacting grammar into a "collection of sounds, a kind of sublime musical mold" as an integral language they called Saṃskṛta . From the late Vedic period onwards, state Annette Wilke and Oliver Moebus, resonating sound and its musical foundations attracted an "exceptionally large amount of linguistic, philosophical and religious literature" in India. Sound
12000-451: The calls of harmless predators, in this case, harmless killer whales. While some researchers prefer to simply describe the adaptive value of observable habituated behavior, others find it useful to infer psychological processes from the observed behavior change. For example, habituation of aggressive responses in male bullfrogs has been explained as "an attentional or learning process that allows animals to form enduring mental representations of
12150-440: The capacity to understand the old Prakrit languages such as Ardhamagadhi . A section of European scholars state that Sanskrit was never a spoken language. However, evidences shows that Sanskrit was a spoken language, essential for oral tradition that preserved the vast number of Sanskrit manuscripts from ancient India. The textual evidence in the works of Yaksa, Panini, and Patanajali affirms that Classical Sanskrit in their era
12300-415: The central nervous system, and CB 2 cannabinoid receptors in the periphery. The latter appear to be involved in functions of the immune system . Cannabinoid receptors were originally discovered as sensitive to Δ- tetrahydrocannabinol (Δ-THC, commonly called THC), which is the primary psychoactive cannabinoid found in cannabis . The discovery of anandamide came from research into CB 1 and CB 2 , as it
12450-527: The close relationship between the Indo-Iranian tongues and the Baltic and Slavic languages , vocabulary exchange with the non-Indo-European Uralic languages , and the nature of the attested Indo-European words for flora and fauna. The pre-history of Indo-Aryan languages which preceded Vedic Sanskrit is unclear and various hypotheses place it over a fairly wide limit. According to Thomas Burrow, based on
12600-614: The context of a speech or language, is found in verses 5.28.17–19 of the Ramayana . Outside the learned sphere of written Classical Sanskrit, vernacular colloquial dialects ( Prakrits ) continued to evolve. Sanskrit co-existed with numerous other Prakrit languages of ancient India. The Prakrit languages of India also have ancient roots and some Sanskrit scholars have called these Apabhramsa , literally 'spoiled'. The Vedic literature includes words whose phonetic equivalent are not found in other Indo-European languages but which are found in
12750-653: The crystallization of Classical Sanskrit. As in this period the Indo-Aryan tribes had not yet made contact with the inhabitants of the South of the subcontinent, this suggests a significant presence of Dravidian speakers in North India (the central Gangetic plain and the classical Madhyadeśa) who were instrumental in this substratal influence on Sanskrit. Extant manuscripts in Sanskrit number over 30 million, one hundred times those in Greek and Latin combined, constituting
12900-408: The demonstration of 1) Recovery by Dishabituation (the brief recovery of the response to the eliciting stimulus when another stimulus is added) to distinguish habituation from sensory adaptation and fatigue. More recently, 2) Sensitivity of Spontaneous Recovery to Rate-of-Stimulation and 3) Stimulus-specificity have been used as experimental evidence for the habituation process. Spontaneous Recovery
13050-467: The detailed and sophisticated treatise then transmitted it through his students. Modern scholarship generally accepts that he knew of a form of writing, based on references to words such as Lipi ('script') and lipikara ('scribe') in section 3.2 of the Aṣṭādhyāyī . The Classical Sanskrit language formalized by Pāṇini, states Renou, is "not an impoverished language", rather it is "a controlled and
13200-512: The development of a novel response (whereas habituation is a decrease in a pre-existing response); 3) the behavioral measure of habituation (i.e., a response-decline) is very susceptible to confound by non-learning factors (e.g., fatigue) which, therefore, make it more difficult to study). Various models have been proposed to account for habituation including the Stimulus-Model Comparator theory formulated by Evgeny Sokolov ,
13350-471: The differences between the Vedic and Classical Sanskrit. Louis Renou published in 1956, in French, a more extensive discussion of the similarities, the differences and the evolution of the Vedic Sanskrit within the Vedic period and then to the Classical Sanskrit along with his views on the history. This work has been translated by Jagbans Balbir. The earliest known use of the word Saṃskṛta (Sanskrit), in
13500-460: The distant major ancient languages of the world. The Indo-Aryan migrations theory explains the common features shared by Sanskrit and other Indo-European languages by proposing that the original speakers of what became Sanskrit arrived in South Asia from a region of common origin, somewhere north-west of the Indus region , during the early 2nd millennium BCE. Evidence for such a theory includes
13650-490: The early medieval era, it became a language of religion and high culture , and of the political elites in some of these regions. As a result, Sanskrit had a lasting impact on the languages of South Asia, Southeast Asia and East Asia, especially in their formal and learned vocabularies. Sanskrit generally connotes several Old Indo-Aryan language varieties. The most archaic of these is the Vedic Sanskrit found in
13800-430: The effect of an extremely inhibited temperament and an extremely uninhibited temperament on habituation. Their study found that over repeated presentations individuals with an uninhibited temperament demonstrated habituation in both the amygdala and hippocampus , whereas participants with an inhibited temperament demonstrated habituation in neither brain region. The researchers suggest that this failure to habituate reflects
13950-473: The eliciting stimulus has declined can cause an increase in the habituated response. This increase in responding is temporary and is called " dishabituation " and always occurs to the original eliciting stimulus (not to the added stimulus). Researchers also use evidence of dishabituation to rule out sensory adaptation and fatigue as alternative explanations of the habituation process. Habituation of dishabituation can occur. The amount of dishabituation that occurs as
14100-548: The first language of the respective speakers. The Sanskrit language brought Indo-Aryan speaking people together, particularly its elite scholars. Some of these scholars of Indian history regionally produced vernacularized Sanskrit to reach wider audiences, as evidenced by texts discovered in Rajasthan, Gujarat, and Maharashtra. Once the audience became familiar with the easier to understand vernacularized version of Sanskrit, those interested could graduate from colloquial Sanskrit to
14250-423: The following: Repeated presentation of a stimulus will cause a decrease in reaction to the stimulus. Habituation is also proclaimed to be a form of implicit learning , which is commonly the case with continually repeated stimuli. This characteristic is consistent with the definition of habituation as a procedure, but to confirm habituation as a process, additional characteristics must be demonstrated. Also observed
14400-425: The former case did the object itself move. Would the infants know the difference? Or would they treat both cases as if the object itself moved? The results revealed a return of looking behavior (dishabituation) when the object's position was changed, but not when the infant's position was changed. Dishabituation indicates that infants perceived a significant change in the stimulus. Therefore, the infants understood when
14550-412: The foundation of Vyākaraṇa, a Vedānga . The Aṣṭādhyāyī was not the first description of Sanskrit grammar, but it is the earliest that has survived in full, and the culmination of a long grammatical tradition that Fortson says, is "one of the intellectual wonders of the ancient world". Pāṇini cites ten scholars on the phonological and grammatical aspects of the Sanskrit language before him, as well as
14700-412: The free amine of cephalin through an N -acyltransferase enzyme. Anandamide synthesis from NAPE occurs via multiple pathways and includes enzymes such as phospholipase A2 , phospholipase C and N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (NAPE-PLD). The crystal structure of NAPE-PLD in complex with phosphatidylethanolamine and deoxycholate shows how the cannabinoid anandamide
14850-537: The gods Varuna, Mitra, Indra, and Nasatya found in the earliest layers of the Vedic literature. O Bṛhaspati, when in giving names they first set forth the beginning of Language, Their most excellent and spotless secret was laid bare through love, When the wise ones formed Language with their mind, purifying it like grain with a winnowing fan, Then friends knew friendships – an auspicious mark placed on their language. — Rigveda 10.71.1–4 Translated by Roger Woodard The Vedic Sanskrit found in
15000-402: The habituation process in prairie dogs may depend on several factors including the particular defensive response. In one study that measured several different responses to the repeated presence of humans, the alarm calls of prairie dogs showed habituation whereas the behavior of escaping into their burrows showed sensitization. Another example of the importance of habituation in the animal world
15150-431: The historic Sanskrit literary culture and the failure of new Sanskrit literature to assimilate into the changing cultural and political environment. Sheldon Pollock states that in some crucial way, "Sanskrit is dead ". After the 12th century, the Sanskrit literary works were reduced to "reinscription and restatements" of ideas already explored, and any creativity was restricted to hymns and verses. This contrasted with
15300-412: The individual". However, also in 1964, a committee from the World Health Organization once again convened and decided the definitions of drug habituation and drug addiction were insufficient, replacing the two terms with "drug dependence". Substance dependence is the preferred term today when describing drug-related disorders, whereas the use of the term drug habituation has declined substantially. This
15450-486: The intense change that must have occurred in the pre-Vedic period between the Proto-Indo-Aryan language and Vedic Sanskrit. The noticeable differences between the Vedic and the Classical Sanskrit include the much-expanded grammar and grammatical categories as well as the differences in the accent, the semantics and the syntax. There are also some differences between how some of the nouns and verbs end, as well as
15600-507: The large protozoan Stentor coeruleus provides an understanding of the cellular mechanisms that are involved in the habituation process. Within psychology , habituation has been studied through different forms of neuroimaging like PET scan and fMRI . Within fMRI, the response that habituates is the blood oxygen level-dependent (BOLD) signals triggered by stimuli. Decreases of the BOLD signal are interpreted as habituation. The amygdala
15750-432: The largest cultural heritage that any civilization has produced prior to the invention of the printing press. — Foreword of Sanskrit Computational Linguistics (2009), Gérard Huet, Amba Kulkarni and Peter Scharf Sanskrit has been the predominant language of Hindu texts encompassing a rich tradition of philosophical and religious texts, as well as poetry, music, drama , scientific , technical and others. It
15900-449: The levels of anandamide and other endocannabinoids in the brain. High fat diet feeding in mice increases levels of anandamide in the liver and increases lipogenesis . Anandamide may be relevant to the development of obesity, at least in rodents. Paracetamol (known as acetaminophen in the US and Canada) is metabolically combined with arachidonic acid by FAAH to form AM404 . This metabolite is
16050-412: The linguistic expression and sets the standard for the Sanskrit language. Pāṇini made use of a technical metalanguage consisting of a syntax, morphology and lexicon. This metalanguage is organised according to a series of meta-rules, some of which are explicitly stated while others can be deduced. Despite differences in the analysis from that of modern linguistics, Pāṇini's work has been found valuable and
16200-514: The literary works. The Indian tradition, states Winternitz , has favored the learning and the usage of multiple languages from the ancient times. Sanskrit was a spoken language in the educated and the elite classes, but it was also a language that must have been understood in a wider circle of society because the widely popular folk epics and stories such as the Ramayana , the Mahabharata ,
16350-461: The medical and scientific communities concluded that stimulus-dependent variability reflexes is clinically normal. The opposition to the considering habituation a form of learning was also based on the assumption that learning processes must produce novel behavioral responses and must occur in the cerebral cortex . Non-associative forms of learning such as habituation (and sensitization ) do not produce novel (conditioned) responses but rather diminish
16500-511: The modern age include the Samaveda , Yajurveda , Atharvaveda , along with the embedded and layered Vedic texts such as the Brahmanas , Aranyakas , and the early Upanishads . These Vedic documents reflect the dialects of Sanskrit found in the various parts of the northwestern, northern, and eastern Indian subcontinent. According to Michael Witzel, Vedic Sanskrit was a spoken language of
16650-429: The more advanced Classical Sanskrit. Rituals and the rites-of-passage ceremonies have been and continue to be the other occasions where a wide spectrum of people hear Sanskrit, and occasionally join in to speak some Sanskrit words such as namah . Classical Sanskrit is the standard register as laid out in the grammar of Pāṇini , around the fourth century BCE. Its position in the cultures of Greater India
16800-401: The most advanced analysis of linguistics until the twentieth century. Pāṇini's comprehensive and scientific theory of grammar is conventionally taken to mark the start of Classical Sanskrit. His systematic treatise inspired and made Sanskrit the preeminent Indian language of learning and literature for two millennia. It is unclear whether Pāṇini himself wrote his treatise or he orally created
16950-602: The most archaic poems of the Iranian and Greek language families, the Gathas of old Avestan and Iliad of Homer . As the Rigveda was orally transmitted by methods of memorisation of exceptional complexity, rigour and fidelity, as a single text without variant readings, its preserved archaic syntax and morphology are of vital importance in the reconstruction of the common ancestor language Proto-Indo-European . Sanskrit does not have an attested native script: from around
17100-597: The numbers are thought to signify a wish to be aligned with the prestige of the language. Sanskrit has been taught in traditional gurukulas since ancient times; it is widely taught today at the secondary school level. The oldest Sanskrit college is the Benares Sanskrit College founded in 1791 during East India Company rule . Sanskrit continues to be widely used as a ceremonial and ritual language in Hindu and Buddhist hymns and chants . In Sanskrit,
17250-446: The object itself moved and when it did not. Only when the object itself moved were they interested in it again (dishabituation). When the object remained in the same position as before it was perceived as the same old boring thing (habituation). In general, habituation/dishabituation procedures help researchers determine the way infants perceive their environments. Habituation is a useful primary tool for then assessing mental processes in
17400-403: The oral transmission of the texts is reliable: they are ceremonial literature, where the exact phonetic expression and its preservation were a part of the historic tradition. However some scholars have suggested that the original Ṛg-veda differed in some fundamental ways in phonology compared to the sole surviving version available to us. In particular that retroflex consonants did not exist as
17550-400: The original stimulus ( stimulus generalization ). The more similar the new stimulus is to the original stimulus, the greater the habituation that will be observed. When a subject shows habituation to a new stimulus that is similar to the original stimulus but not to a stimulus that is different from the original stimulus, then the subject is showing stimulus discrimination . (For example, if one
17700-431: The other." Reinöhl further states that there is a symmetric relationship between Dravidian languages like Kannada or Tamil, with Indo-Aryan languages like Bengali or Hindi, whereas the same relationship is not found for non-Indo-Aryan languages, for example, Persian or English: A sentence in a Dravidian language like Tamil or Kannada becomes ordinarily good Bengali or Hindi by substituting Bengali or Hindi equivalents for
17850-414: The physical properties of a repeated stimulus and to shift their focus of attention away from sources of irrelevant or unimportant stimulation". Habituation of innate defensive behaviors is also adaptive in humans, such as habituation of a startle response to a sudden loud noise. But habituation is much more ubiquitous even in humans. An example of habituation that is an essential element of everyone's life
18000-414: The possible influence of Dravidian on Sanskrit is only one of many items of syntactic assimilation, not least among them the large repertoire of morphological modality and aspect that, once one knows to look for it, can be found everywhere in classical and postclassical Sanskrit". The main influence of Dravidian on Sanskrit is found to have been concentrated in the timespan between the late Vedic period and
18150-439: The previous 1,500 years when "great experiments in moral and aesthetic imagination" marked the Indian scholarship using Classical Sanskrit, states Pollock. Scholars maintain that the Sanskrit language did not die, but rather only declined. Jurgen Hanneder disagrees with Pollock, finding his arguments elegant but "often arbitrary". According to Hanneder, a decline or regional absence of creative and innovative literature constitutes
18300-480: The problems of interpretation and misunderstanding. The purifying structure of the Sanskrit language removes these imperfections. The early Sanskrit grammarian Daṇḍin states, for example, that much in the Prakrit languages is etymologically rooted in Sanskrit, but involves "loss of sounds" and corruptions that result from a "disregard of the grammar". Daṇḍin acknowledged that there are words and confusing structures in Prakrit that thrive independent of Sanskrit. This view
18450-609: The regional Prakrit languages, which makes it likely that the interaction, the sharing of words and ideas began early in the Indian history. As the Indian thought diversified and challenged earlier beliefs of Hinduism, particularly in the form of Buddhism and Jainism , the Prakrit languages such as Pali in Theravada Buddhism and Ardhamagadhi in Jainism competed with Sanskrit in the ancient times. However, states Paul Dundas , these ancient Prakrit languages had "roughly
18600-455: The regulation of anandamide levels. Subsequently, anandamide has been proposed as a biomarker of infertility , but so far lacks any predictive values in order to be used clinically. Both the CB1 and CB2 receptors (the binding site of anandamide) are under research for a possible role in positive and negative interpretation of environment and setting. The binding relationship of anandamide and
18750-497: The relationship between various Indo-European languages, the origin of all these languages may possibly be in what is now Central or Eastern Europe, while the Indo-Iranian group possibly arose in Central Russia. The Iranian and Indo-Aryan branches separated quite early. It is the Indo-Aryan branch that moved into eastern Iran and then south into South Asia in the first half of the 2nd millennium BCE. Once in ancient India,
18900-562: The role of language, the ontological status of painting word-images through sound, and the need for rules so that it can serve as a means for a community of speakers, separated by geography or time, to share and understand profound ideas from each other. These speculations became particularly important to the Mīmāṃsā and the Nyaya schools of Hindu philosophy, and later to Vedanta and Mahayana Buddhism, states Frits Staal —a scholar of Linguistics with
19050-405: The same cannabinoid receptors that THC found in cannabis acts on. Anandamide can be found within tissues in a wide range of animals. It has also been found in plants, such as the cacao tree. Anandamide is derived from the non-oxidative metabolism of arachidonic acid , an essential omega-6 fatty acid . It is synthesized from N -arachidonoyl phosphatidylethanolamine by multiple pathways. It
19200-406: The same position on a table. Once the infants habituated to the object (i.e., spent less time looking at it) either the object was spatially moved while the infant remained at the same place near the table or the object was left in the same place but the infant was moved to the opposite side of the table. In both cases, the spatial relationship between the object and the infant had changed, but only in
19350-496: The same relationship to Sanskrit as medieval Italian does to Latin". The Indian tradition states that the Buddha and the Mahavira preferred the Prakrit language so that everyone could understand it. However, scholars such as Dundas have questioned this hypothesis. They state that there is no evidence for this and whatever evidence is available suggests that by the start of the common era, hardly anybody other than learned monks had
19500-556: The semi-nomadic Aryans . The Vedic Sanskrit language or a closely related Indo-European variant was recognized beyond ancient India as evidenced by the " Mitanni Treaty" between the ancient Hittite and Mitanni people, carved into a rock, in a region that now includes parts of Syria and Turkey. Parts of this treaty, such as the names of the Mitanni princes and technical terms related to horse training, for reasons not understood, are in early forms of Vedic Sanskrit. The treaty also invokes
19650-451: The sensitization process exceeds the habituation process, behavior shows sensitization. Groves and Thompson hypothesize the existence of two neural pathways: an "S-R pathway" involved with the habituation process, and a "state pathway" involved with sensitization. The state system is seen as equivalent to a general state of arousal. Habituation has been observed in an enormously wide range of species from motile single-celled organisms such as
19800-615: The social structures such as the role of the poet and the priests, the patronage economy, the phrasal equations, and some of the poetic metres. While there are similarities, state Jamison and Brereton, there are also differences between Vedic Sanskrit, the Old Avestan, and the Mycenaean Greek literature. For example, unlike the Sanskrit similes in the Ṛg-veda, the Old Avestan Gathas lack simile entirely, and it
19950-740: The stages of infancy. The purpose for these tests, or paradigms records looking time, which is the baseline measurement. Habituation of looking time helps to assess certain child capabilities such as: memory, sensitivity, and helps the baby recognize certain abstract properties. Habituation is also found to be influenced by unchangeable factors such as infant age, gender, and complexity of the stimulus. (Caron & Caron, 1969; Cohen, DeLoache, & Rissman, 1975; Friedman, Nagy, & Carpenter, 1970; Miller, 1972; Wetherford & Cohen, 1973). Though there are various challenges that come with habituation. Some infants have preferences for some stimuli based on their static or dynamic properties. Infant dishabituation also
20100-542: The stimulus repeatedly occurs but causes no harm. An example of this is the prairie dog habituating to humans. Prairie dogs give alarm calls when they detect a potentially dangerous stimulus. This defensive call occurs when any mammal, snake, or large bird approaches them. However, they habituate to noises, such as human footsteps, that occur repeatedly but result in no harm to them. If prairie dogs never habituate to nonthreatening stimuli, they would be constantly sending out alarm calls and wasting their time and energy. However,
20250-409: The stimulus, the experienced stimulus is compared with the stimulus model. If the experienced stimulus matches the stimulus model, responding is inhibited. At first the stimulus model is not a very good representation of the presented stimulus, and thus responding continues because of this mismatch. With additional presentations the stimulus model is improved, there is no longer a mismatch, and responding
20400-441: The stimulus. When changes to the habituated stimulus are made (or a new stimulus is introduced), the looking behavior returns (dishabituates). A recent fMRI study revealed that the presentation of a dishabituating stimulus has an observable, physical effect upon the brain. In one study the mental spatial representations of infants were assessed using the phenomenon of dishabituation. Infants were presented repeatedly with an object in
20550-464: The subsequent eye-blink response is recorded directly by observation or by electromyography (EMG). Depending on the disorder, habituation phenomena have been implicated as a cause, symptom, or therapy. Reduced habituation is the most common habituation phenotype reported across neuropsychiatric disorders although enhanced habituation has been observed in HD and ADHD. It also appears that abnormal habituation
20700-653: The turn of the 1st-millennium CE, it has been written in various Brahmic scripts , and in the modern era most commonly in Devanagari . Sanskrit's status, function, and place in India's cultural heritage are recognized by its inclusion in the Constitution of India 's Eighth Schedule languages . However, despite attempts at revival, there are no first-language speakers of Sanskrit in India. In each of India's recent decennial censuses, several thousand citizens have reported Sanskrit to be their mother tongue, but
20850-408: The variants in the usage of Sanskrit in different regions of India. The ten Vedic scholars he quotes are Āpiśali, Kaśyapa , Gārgya, Gālava, Cakravarmaṇa, Bhāradvāja , Śākaṭāyana, Śākalya, Senaka and Sphoṭāyana. In the Aṣṭādhyāyī , language is observed in a manner that has no parallel among Greek or Latin grammarians. Pāṇini's grammar, according to Renou and Filliozat, is a classic that defines
21000-564: The vernacular Prakrits. Many Sanskrit dramas indicate that the language coexisted with the vernacular Prakrits. The cities of Varanasi , Paithan , Pune and Kanchipuram were centers of classical Sanskrit learning and public debates until the arrival of the colonial era. According to Lamotte , Sanskrit became the dominant literary and inscriptional language because of its precision in communication. It was, states Lamotte, an ideal instrument for presenting ideas, and as knowledge in Sanskrit multiplied, so did its spread and influence. Sanskrit
21150-502: The Ṛg-veda is distinctly more archaic than other Vedic texts, and in many respects, the Rigvedic language is notably more similar to those found in the archaic texts of Old Avestan Zoroastrian Gathas and Homer's Iliad and Odyssey . According to Stephanie W. Jamison and Joel P. Brereton – Indologists known for their translation of the Ṛg-veda – the Vedic Sanskrit literature "clearly inherited" from Indo-Iranian and Indo-European times
21300-408: Was a spoken language ( bhasha ) used by the cultured and educated. Some sutras expound upon the variant forms of spoken Sanskrit versus written Sanskrit. Chinese Buddhist pilgrim Xuanzang mentioned in his memoir that official philosophical debates in India were held in Sanskrit, not in the vernacular language of that region. According to Sanskrit linguist professor Madhav Deshpande, Sanskrit
21450-427: Was a spoken language in a colloquial form by the mid-1st millennium BCE which coexisted with a more formal, grammatically correct form of literary Sanskrit. This, states Deshpande, is true for modern languages where colloquial incorrect approximations and dialects of a language are spoken and understood, along with more "refined, sophisticated and grammatically accurate" forms of the same language being found in
21600-472: Was adopted voluntarily as a vehicle of high culture, arts, and profound ideas. Pollock disagrees with Lamotte, but concurs that Sanskrit's influence grew into what he terms a "Sanskrit Cosmopolis" over a region that included all of South Asia and much of southeast Asia. The Sanskrit language cosmopolis thrived beyond India between 300 and 1300 CE. Today, it is believed that Kashmiri is the closest language to Sanskrit. Reinöhl mentions that not only have
21750-738: Was also the language of some of the oldest surviving, authoritative and much followed philosophical works of Jainism such as the Tattvartha Sutra by Umaswati . The Sanskrit language has been one of the major means for the transmission of knowledge and ideas in Asian history. Indian texts in Sanskrit were already in China by 402 CE, carried by the influential Buddhist pilgrim Faxian who translated them into Chinese by 418 CE. Xuanzang , another Chinese Buddhist pilgrim, learnt Sanskrit in India and carried 657 Sanskrit texts to China in
21900-536: Was found to improve lipid resistance and lipid profile in obese subjects with type 2 diabetes . Elevated anandamide levels are found in people with nonalcoholic fatty liver disease , nonalcoholic steatohepatitis , and liver fibrosis . The American Academy of Dermatology has named topical anandamide a promising therapy for cutaneous lupus erythematosus . In humans, anandamide is biosynthesized from N -arachidonoyl phosphatidylethanolamine (NAPE). In turn, NAPE arises by transfer of arachidonic acid from lecithin to
22050-399: Was habituated to the taste of lemon, their responding would increase significantly when presented with the taste of lime). Stimulus discrimination can be used to rule out sensory adaptation and fatigue as an alternative explanation of the habituation process. Another observation mentioned is when a single introduction of a different stimulus late in the habituation procedure when responding to
22200-533: Was inevitable that a naturally occurring (endogenous) chemical would be found to affect these receptors. Anandamide is under research for its potential involvement in the implantation of the early stage embryo in its blastocyst form into the uterus . Therefore, cannabinoids such as Δ-THC might influence processes during the earliest stages of human pregnancy. Peak plasma anandamide occurs at ovulation and positively correlates with peak estradiol and gonadotrophin levels, suggesting that these may be involved in
22350-542: Was that an increase in the frequency of stimulus presentation (i.e., shorter interstimulus interval ) will increase the rate of habituation. Furthermore, continued exposure to the stimulus after the habituated response has plateaued (i.e., show no further decrement) may have additional effects on subsequent tests of behavior such as delaying spontaneous recovery. The concepts of stimulus generalization and stimulus discrimination will be observed. Habituation to an original stimulus will also occur to other stimuli that are similar to
22500-442: Was visualized as "pervading all creation", another representation of the world itself; the "mysterious magnum" of Hindu thought. The search for perfection in thought and the goal of liberation were among the dimensions of sacred sound, and the common thread that wove all ideas and inspirations together became the quest for what the ancient Indians believed to be a perfect language, the "phonocentric episteme" of Sanskrit. Sanskrit as
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