The Bezirksliga Main-Hessen was the highest association football league in the German state of Hesse and the Prussian province of Hesse-Nassau from 1923 to 1927, when the league was replaced by the Bezirksliga Main-Hessen .
99-693: The league was formed in 1923, after a league reform which was decided upon in Darmstadt , Hesse . It replaced the Kreisliga Nordmain and the Kreisliga Südmain as the highest leagues in the region. Apart from clubs from Hesse, with the Viktoria Aschaffenburg , the league also included one club from Bavaria . The Bezirksliga Main , named after the river Main , started out with eight teams, playing each other in
198-573: A capital city that it has many architectural testimonies of this period. Many of its major architectural landmarks were created by Georg Moller who was appointed the court master builder of the Grand Duchy of Hesse. Due to the fact that the last ruling Grand Duke of Hesse, Ernst Ludwig was a grandson of Queen Victoria and brother to Empress Alexandra of Russia , the architecture of Darmstadt has been influenced by British and Russian imperial architecture with many examples still existing, such as
297-547: A church presbytery. The most important Catholic Church is St. Ludwig in central Darmstadt. The Russian Chapel in Darmstadt is a Russian orthodox church which is still in use. It was built and used as a private chapel by the last Tsar of Russia, Nicholas II , whose wife Alexandra was born in Darmstadt. Although Russian orthodox churches also exist in other cities outside Russia, the Russian Chapel in Darmstadt
396-523: A home-and-away round with the league winner advancing to the Southern German championship , which in turn was a qualification tournament for the German championship . The league modus remained unchanged for its first three seasons, 1923–24, 1924–25 and 1925–26. For its last edition however, it expanded to ten clubs. Additionally, the leagues runners-up also qualified for a "consolidation" round with
495-407: A major part of the city's economy. It is also home to the football club SV Darmstadt 98 . Alexandra Feodorovna (Alix of Hesse) , the wife of Nicholas II of Russia , as well as Maria Alexandrovna (Marie of Hesse) , the wife of Alexander II of Russia , who were related, were born in this city. The name Darmstadt first appears towards the end of the 11th century, then as Darmundestat . Darmstadt
594-466: A member of an American branch of the Merck family, repurchased the stock in 1919. It is known as MSD ( Merck Sharp and Dohme ) outside of North America. The original Merck of Darmstadt holds the rights to the name Merck in all countries except the U.S. and Canada, where it is known as EMD ( Emanuel Merck, Darmstadt ), and the life science business specifically is known as MilliporeSigma. In 2015 Merck adopted
693-624: A new product category, and Vigantol was introduced in 1927, followed by Cebion in 1934. Following the defeat of Germany in World War II , Merck was granted permission by the military government to produce drugs, pesticides, food preservatives, reagents, and fine chemicals for laboratory use. Soon afterward the boom that is commonly known as the " Wirtschaftswunder " (economic miracle) set in. For Merck, this meant two-digit sales-growth figures for many years. Products of this time included corticoid preparations — for example Fortecortin , which
792-467: A new visitor center at its Darmstadt site in the early 2010s. By 2015 the site's pyramid had been torn down as part of the renovations. In April 2017, the company announced it had completed the acquisition of food safety testing company, BioControl Systems Inc. In August of the same year the company announced the acquisition of Natrix Separations for an undisclosed sum. In April 2019, Merck announced it would acquire Versum Materials . The acquisition
891-547: A partnership with Quintiles in which the latter helps the former in the clinical development of all its compounds. In February 2019, Merck also announced a partnership with GSK to develop and commercialize M7824 (bintrafusp alfa*), a new Immunotherapy with potential in various difficult-to-treat cancers. In 2020, Merck launched partnership with Pechoin in China to develop "high-tech herbal" skincare products . The life science business of Merck, formerly known as Merck Millipore,
990-540: A place to research the German language. The academy's annual Georg Büchner Prize , named in memory of Georg Büchner , is considered the most prestigious literary award for writers of German language. Darmstadt is located in the Upper Rhine Plain (German: Oberrheinische Tiefebene), a major rift, about 350 km (217 mi) long and on average 50 km (31 mi) wide, between the cities of Frankfurt in
1089-667: A public tender offer for the remaining shares starting in November 2006. The combined company has an R&D budget of approximately $ 1.1 billion and sales of approximately $ 4.6 billion. Its approximately $ 2 billion in sales of biologics would make it seventh among pharmaceutical/biotech companies. The new entity, Merck Serono , began operations in 2007. Merck KGaA established its philanthropic foundation in 2008 called Merck Foundation. Rasha Kelej currently serves as its CEO. In 2010, Merck took over Billerica (MA) based Millipore Corporation for EUR 5.3 billion (US$ 7.2 billion). It
SECTION 10
#17327806117831188-575: A separate industry based research educational institution in 1971 and is the largest University of Applied Sciences in Hesse (German: Hessen ) with about 16,500 students. The TU Darmstadt is one of the important technical institutes in Germany and is well known for its research and teaching in the Electrical, Mechanical and Civil Engineering disciplines. Together with other tertiary institutions,
1287-560: A supported offer for Schering and Merck decided to drop out of the bidding for the company. Schering is not to be confused with Schering-Plough which was once part of Schering AG but was acquired by Merck & Co. in 2009. In September 2006 the company announced a takeover bid of $ 13.2 billion for Serono SA, Switzerland's largest biotech firm. The deal included a buy-out of the Bertarelli family's 64.5% stake in Serono to be followed by
1386-538: A uniform brand identity for all its subsidiaries, and the company has stressed its intention to protect the brand of "the real Merck" globally and initiated litigation against its former subsidiary over use of the name. In 2018, the company celebrated their 350th anniversary. Merck has formed a strategic alliance with the Technische Universität Darmstadt , which is located in the same town as Merck. The roots of Merck reach back as far as
1485-607: Is Erbitux ( cetuximab ), for which it has marketing rights worldwide, apart from North America. (Cetuximab was discovered by Imclone Systems , and is marketed in North America by Bristol-Myers Squibb .) Other areas of Expertise from Merck Healthcare include Fertility, Endocrinology and General Medicine, the later focusing on treatments for Diabetes, Thyroid disease and Cardiovascular diseases. Some products from Merck include Metformin , Bisoprolol , Levothyroxine and Digitoxin . Merck's clinical research strategy consists of
1584-417: Is a botanical garden maintained by the Technische Universität Darmstadt with a fine collection of rare plants and trees. The Protestant Stadtkirche Darmstadt built in 1369, is in the pedestrian zone of the downtown city center, next to the historic Hotel Bockshaut. The church has gothic elements along with renaissance and baroque , it houses the royal crypt . Hotel Bockshaut was built in 1580 for
1683-566: Is a city in the state of Hesse in Germany, located in the southern part of the Rhine-Main-Area (Frankfurt Metropolitan Region) . Darmstadt has around 160,000 inhabitants, making it the fourth largest city in the state of Hesse after Frankfurt am Main , Wiesbaden , and Kassel . Darmstadt holds the official title "City of Science" (German: Wissenschaftsstadt ) as it is a major centre of scientific institutions, universities, and high-technology companies. The European Organisation for
1782-463: Is a major base for low-cost carrier Ryanair . This airport can only be reached by car or bus. Darmstadt is served by several national and European bus links which connect Darmstadt with other German and European cities. Darmstadt was the capital of an independent country (the Grand Duchy of Hesse ) until 1871 and the capital of the German state of Hesse until 1945. It is due to its past as
1881-556: Is an officially recognised and Church-sponsored University. The sponsors are the Protestant Church in Hesse and Nassau, the Protestant Church of Kurhesse-Waldeck and the social welfare organisation of both Hessian Protestant Churches, the Diakonie Hesse. The EHD has approximately 1,700 students, 40 professors and 10 scientific employees and about 100 visiting lecturers every semester. The city's main professional club
1980-464: Is commonly known by its German name, Jugendstil. The name is taken from the artistic journal, Die Jugend, which was published in Munich and which espoused the new artistic movement. It was founded in 1896 by Georg Hirth (Hirth remained editor until his death in 1916, and the magazine continued to be published until 1940). The magazine was instrumental in promoting the style in Germany. As a result, its name
2079-441: Is considering options for its consumer-health division, including a potential full or partial sale, or strategic partnership. An equity analyst estimated the unit could command a purchase price of €1.8 billion to €2.7 billion from a full sale. In December Reuters reported that both Nestlé and private equity owners of Stada were preparing bids for Merck's consumer health group. Days later, Reuters again reported that Perrigo
SECTION 20
#17327806117832178-597: Is dedicated to solutions and reagents for protein research and cell biology, cell culture solutions , as well as to products and services for the development of biopharmaceutical agents. The scope of activities of Lab Solutions included laboratory chemicals and other materials for research, science and industry, products and services for sampling, and test kits for the pharmaceutical, foods and diagnostics industries, along with products, consumables and services surrounding highly purified laboratory water for science and industry. Process Solutions focused on products and services for
2277-501: Is effective in the treatment of the rare genetic disorder PKU , however Merck is moving away from genetics into cancer treatment , immunology and neurology . In October, it was announced that Karl-Ludwig Kley , CEO of Merck since April 2007, would retire in April 2016, and be succeeded by Stefan Oschmann , who has been a member of the executive board since 2011. The company started building new facilities for its R&D operations and
2376-534: Is more live music -oriented, is held in the same location every year in May. These two festivals attract 700,000 and 400,000 visitors respectively. Darmstadt has a rich cultural heritage. The Staatstheater Darmstadt dates back to the year 1711. The present building has been in use since 1972 and has three halls which can be used independently. The "Grand Hall" (Großes Haus) provides seats for 956 people and serves as Darmstadt's opera house. The "Small Hall" (Kleines Haus)
2475-706: Is mostly used for plays and dance and has 482 seats. A separate small hall (Kammerspiele), with 120 seats, is used for chamber plays . Among the museums in Darmstadt the most important are the Hessisches Landesmuseum (Hessian State Museum), the Porcelain Museum (exhibition of the ducal porcelain), the Schlossmuseum (exhibition of the ducal residence and possessions), the Kunsthalle Darmstadt (exhibitions of modern art),
2574-461: Is now Merck's life science business unit. With the acquisition of Millipore, Merck is consolidating its US holdings and shutting down the Gibbstown facility and warehouse. Gibbstown operations will be transferred to the new Philadelphia office and Millipore headquarters. Merck Korea received the "Leading Investor Award" at the 5th Korea-EU Industrial Cooperation Day in 2011. In December 2013,
2673-429: Is still used today — the cold remedy Nasivin or the hormone preparations Gestafortin and Mantova. Merck currently employs over 2,500 people in its 4 R&D hubs via. Boston , Darmstadt , Beijing and Tokyo. In the year 2018, Merck invested over €1,6 billion in its R&D operations. The focus of Merck's current pharmaceutical R&D is on oncology , neurology and immunology. In oncology, its first marketed product
2772-508: Is the football club SV Darmstadt 98 , who play at the Merck-Stadion am Böllenfalltor . Other, amateur football clubs are 1. FCA Darmstadt and Rot-Weiß Darmstadt . Merck Group The Merck Group , branded and commonly known as Merck , is a German multinational science and technology company headquartered in Darmstadt , with about 60,000 employees and a presence in 66 countries. The group includes around 250 companies;
2871-548: Is the legal successor of the original Merck and retains the rights to the name "Merck" in all countries except the U.S. and Canada, it is sometimes known as the "German Merck" or "Merck Darmstadt" in North America. The company was formerly also referred to as "E. Merck" (Emanuel Merck). In the years of the Nazi rule , the company was led by Karl Emanuel Merck who became a member of the Nazi Party in 1933 and subsequently received
2970-425: Is the sole legal successor of the original Merck and retains the rights to the trademark "Merck" in all countries except the U.S. and Canada, where "EMD" brand is mostly used (it was introduced alongside Merck's 2001 logo ). In recent branding campaigns, the company has referred to itself as "the original Merck" and "the real Merck". The company was legally known as E. Merck oHG until 1995, when Merck KGaA became
3069-524: The WirtschaftsWoche test ranking Germany's high-tech regions. The roots of Darmstadt University of Applied Sciences goes back to 1876 along with Technische Universität Darmstadt (the first electrical engineering chair and inventions fame), when both these Universities were an integrated entities, a need for a separate industry based research educational institution was felt in the early 1930s, finally University of Applied sciences emerged as
Bezirksliga Main - Misplaced Pages Continue
3168-523: The Darmstadt artists' colony , a major centre of the Jugendstil artistic movement, referring both to the group of artists active in the city in the late 19th and early 20th century, as well as the buildings which they designed, together with the Russian Chapel in Darmstadt , was recognized as a World Heritage Site by UNESCO in 2021. Darmstadt was formerly the capital of a sovereign state,
3267-583: The Glaxo Group . In the early 1980s Merck Group built a visitor center at its Darmstadt headquarters that featured a pyramid. Merck was legally named E. Merck oHG until 1995. In 1995 it was listed on the Frankfurt Stock Exchange and became a KGaA , legally named Merck KGaA . On 13 March 2006, Merck announced a takeover bid for Schering AG , the world's largest producer of oral contraceptives. On 23 March 2006, Bayer AG made
3366-545: The Grand Duchy of Hesse and its successor, the People's State of Hesse , a federal state of Germany. As the capital of an increasingly prosperous duchy , the city gained some international prominence and remains one of the wealthiest cities in Europe. In the 20th century, industry (especially chemicals), as well as large science and electronics (and later, information technology) sectors became increasingly important, and are still
3465-512: The Rhein-Main Metropolitan Area ). The backbone of public transport in Darmstadt is the tram system with 10 lines. Local bus lines also serve all parts of the city and the city is served by regional bus lines. The historically important local airfield August Euler Airfield is closed to aviation at large, being reserved for the use of the Technische Universität Darmstadt . Darmstadt can be easily accessed from around
3564-658: The Rhine-Main S-Bahn , which connects the city to Frankfurt . Within Darmstadt the S3 also stops at stations in Darmstadt-Arheilgen and Darmstadt-Wixhausen . Regional trains also connect six secondary railway stations within Darmstadt, and stations in the surrounding region, with Darmstadt Hauptbahnhof . The extensive public transport system of Darmstadt is integrated in the RMV (the transportation authority of
3663-528: The UK . Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine . Merck was privately owned until going public on the Frankfurt Stock Exchange in 1995 and is listed on the DAX index of Germany's top companies. The Merck family still controls a majority of 70.3% of the company's shares. The Merck Group includes around 250 companies in 180 countries;
3762-479: The pharmacy 's laboratory, and by doing so also invented a number of drugs. He began the manufacture of these substances "in bulk" in 1827, touting them as a "Cabinet of Pharmaceutical and Chemical Innovations". He and his successors gradually built up a chemical - pharmaceutical factory that produced — in addition to raw materials for pharmaceutical preparations — a multitude of other chemicals and (from 1890) medicines. In 1891, Georg(e) Merck established himself in
3861-565: The 17th century in the Landgraviate of Hesse-Darmstadt (now a part of Germany). In 1668, Friedrich Jacob Merck , an apothecary , assumed ownership of the Engel-Apotheke ( lit. ' Angel Pharmacy ' ) in Darmstadt . In 1816, Emanuel Merck , a descendant of the original founder, took over the pharmacy. Thanks to his scientific education he was successful in isolating and characterizing several different alkaloids in
3960-784: The 19th and 20th centuries, Darmstadt became home to many technology companies and research institutes, and has been promoting itself as a "city of science" since 1997. It is well known as a high-tech centre in the vicinity of Frankfurt Airport , with important activities in spacecraft operations (the European Space Agency 's European Space Operations Centre , European Organisation for the Exploitation of Meteorological Satellites ), chemistry, pharmacy, information technology, biotechnology, telecommunications (substantial Deutsche Telekom presence) and mechatronics. In 2000, its region also scored Rank 3 amongst 97 German regions in
4059-563: The CEO of the life science business of Merck. The Life Science business sponsors several award programs for graduate students. One of these awards, the Alfred R. Bader Award for Student Innovation recognizes advanced chemistry graduate students, typically in the field of synthetic organic chemistry. Semiconductor Solutions is the largest business unit within Merck's Electronics business sector. It provides materials, delivery systems, and services for
Bezirksliga Main - Misplaced Pages Continue
4158-634: The Darmstadt region is Frankenstein Castle due to claims that the real castle may have had an influence on Mary Shelley's decision to choose the name Frankenstein for her monster-creating scientist. This castle dates back to the 13th century, but it was acquired by the counts of Hesse-Darmstadt in 1662. Darmstadt has a rich tradition in modern architecture. After 1945 several "Meisterbauten" ( Masterful Architectonic Creations ) were built that set standards for modern architecture. These buildings still exist and are used for various public and private purposes. In
4257-413: The Exploitation of Meteorological Satellites (EUMETSAT) and the European Space Agency 's European Space Operations Centre (ESA ESOC) are located in Darmstadt, as well as GSI Centre for Heavy Ion Research , where several chemical elements such as bohrium (1981), meitnerium (1982), hassium (1984), darmstadtium (1994), roentgenium (1994), and copernicium (1996) were discovered. The existence of
4356-434: The German variant of Art Nouveau . Also during this period, in 1912 the chemist Anton Kollisch , working for the pharmaceutical company Merck , first synthesised the chemical MDMA (ecstasy) in Darmstadt. Darmstadt's municipal area was extended in 1937 to include the neighbouring localities of Arheilgen and Eberstadt, and in 1938 the city was separated administratively from the surrounding district ( Kreis ). Darmstadt
4455-516: The Luisenplatz with its grand-ducal column, the old Hessian State Theatre (at Karolinenplatz) and the Russian Chapel by Leon Benois . The Russian church, St. Mary Magdalene Chapel, is named in honor of the patron saint of Tsar Nicholas' mother and was built of Russian stone on Russian soil brought to Darmstadt by train. It was used by the Russian imperial family and court during regular visits to
4554-624: The Merck name. In 2016, the High Court of Justice in the United Kingdom ruled that MSD had breached an agreement with its former parent company and that only Merck of Darmstadt is entitled to use the Merck name in the United Kingdom; the judge also held that MSD's use of "Merck" as part of branding on its global websites were directed to the UK and infringed Merck's trade mark rights in the UK. In response, MSD has initiated counter-litigation in
4653-586: The Netherlands, the Baltic states, and Nordic countries. The two main centres for Jugendstil art in Germany were Munich and Darmstadt. The Luisenplatz , the central square of the city, forms the centre of the city and is the main public transport hub. In 1844 the Ludwigsäule (called Langer Lui , meaning Long Ludwig ), a 33-metre (108 ft) column commemorating Ludwig I , first Grand Duke of Hesse ,
4752-535: The TU is responsible for the large student population of the city, which stood at 33,547 in 2004. Darmstadt has nine official 'Stadtteile' ( boroughs ). These are: The current mayor of Darmstadt is Hanno Benz of SPD , who was elected in 2023. The following is a list of mayors since 1945: The Darmstadt city council ( Stadtverordnetenversammlung ) governs the city alongside the Mayor. The most recent city council election
4851-529: The Tsarina's brother and family in Darmstadt. The Residential Palace Darmstadt ( Stadtschloss ) is located in the city centre. It was the residence of the counts of Hesse-Darmstadt , later as Grand Dukes of Hesse by the grace of Napoleon. The rulers of Hesse also owned Jagdschloss Kranichstein , a hunting lodge in Kranichstein which is a nowadays used as a five star hotel. The most famous castle in
4950-775: The United States and set up Merck & Co. with Theodore Weicker in New York. Merck & Co. was confiscated following the First World War and set up as an independent company in the United States. Today, the US company, which operates as Merck Sharp and Dohme (MSD) outside the U.S. and Canada, has about 68,000 employees (December 2021) in 120 countries. It is one of the top 5 pharmaceutical companies worldwide, larger than its German ancestor, which employs 60,334 people in 67 countries (December 2021). While Merck in Darmstadt
5049-533: The United States. After those controversies, Merck also adopted a new logo for EMD. The same look was also given to the logos of EMD Serono, MilliporeSigma, and EMD Performance Materials (renamed EMD Electronics in March 2021) divisions. Its corporate website is merckgroup.com in the world excluding U.S. and Canada, displaying normal Merck logo in the header, and emdgroup.com in U.S. and Canada, displaying use of its corporate name, Merck KGaA, Darmstadt, Germany, in
SECTION 50
#17327806117835148-542: The biopharma manufacturing processes of its clients with single-use products. In 2015, Merck acquired SigmaAldrich and combined it with Merck Millipore. The company was branded Merck globally and MilliporeSigma in the United States and Canada The newly established life science business of Merck has 300,000 products and three business units: Research Solutions, Process Solutions and Applied Solutions. The company serves customers in biotech, pharma, diagnostics, food safety, academia, and environmental. Matthias Heinzel serves as
5247-418: The brand name Xirallic . Currently, this business unit pools all activities for pigments in lacquering, printing, and plastic applications, in the field of security technology (for instance counterfeiting protection), pigments for applications in the food and pharmaceutical areas, functional materials, and active substances and pigments for cosmetics. M Ventures is a venture capital fund of Merck. In 2021,
5346-478: The businesses mRNA vaccine capabilities as well as its treatment and diagnostics offerings. In March, its Performance Materials division changed name to Electronics division. In December of the same year, EMD Serono (Merck Group operations in the US and Canada) announced it would acquire Swiss-based Chord Therapeutics and its lead drug cladribine , used in generalised myasthenia gravis and neuromyelitis optica spectrum disorder . In September 2017, Merck said it
5445-470: The catholic secondary school Edith-Stein-Schule , the Adventists ' Schulzentrum Marienhöhe , an anthroposophic Waldorf School , a Comenius School and other faith based private schools. The Technical University of Darmstadt (German: Technische Universität Darmstadt ), commonly referred to as TU Darmstadt, is a prestigious research university in Germany. It was founded in 1877 and received
5544-522: The city was also the location of a subcamp of the Natzweiler-Struthof concentration camp . Several prominent members of the German resistance movement against the Nazis were citizens of Darmstadt, including Wilhelm Leuschner and Theodor Haubach , both executed for their opposition to Hitler's regime. Darmstadt was first bombed on 30 July 1940, and 34 other air raids would follow before
5643-407: The commercial manufacture of morphine for an expanding global market. From 1884 onwards, Merck also played role in the production and marketing of cocaine . Sigmund Freud , author of Über Coca (1884), was an enthusiastic collaborator in Merck's cocaine research, though the methodological sophistication of his self-experimentation studies has been challenged. Attention was directed at vitamins as
5742-646: The company bought AZ Electronic Materials SA (AZEM) for about $ 2.6 billion in cash to increase its offering of specialty chemicals to the electronics industry. In September 2014 Merck halted the clinical development of two drug candidates in development with Oxygen Biotherapeutics . One drug candidate suffered a lack of success in patient recruitment , with its MUC1 antigen-specific cancer immunotherapy drug, tecemotide (L-BLP25), missing its Phase I/II endpoint of increasing overall survival in patients with Stage III non-small cell lung cancer . Later in September it
5841-408: The company's account, 265 forced laborers were working in the plant in Darmstadt, most of them women from Russia and Poland. Additionally, several hundred Fremdarbeiter ("foreign workers") from France and Belgium were employed throughout the war years. An air raid on 12 December 1944 destroyed nearly 70 percent of the plant and killed 55 employees. In 1973, Merck Ltd. acquired BDH Chemicals from
5940-421: The company's portfolio in electronic materials was significantly expanded. The launch of the integrated organization was done on 1 June 2020. Merck started working on effect pigments in 1957. The business unit is called Surface Solutions. The core markets for Surface Solutions are automotive coatings, cosmetics, and, to a smaller extent, industrials. An example of its pigments is alumina effect pigments sold under
6039-418: The current main parent company of the group, since 1995, is named Merck KGaA , and is itself mainly owned by the former main parent company, E. Merck oHG , which now operates as a holding company . The American pharmaceutical company Merck & Co. was established as a subsidiary of Merck in 1891, but was nationalized by the United States in 1917, before being privatized again when George W. Merck ,
SECTION 60
#17327806117836138-906: The exhibition centre Mathildenhöhe, and the Museum Künstlerkolonie ( Art Nouveau museum). The Jazz-Institut Darmstadt is Germany's largest publicly accessible jazz archive. The Internationales Musikinstitut Darmstadt, harboring one of the world's largest collections of post-war sheet music , also hosts the biennial Internationale Ferienkurse für Neue Musik , a summer school in contemporary classical music founded by Wolfgang Steinecke . A large number of avant-garde composers have attended and given lectures there, including Olivier Messiaen , Luciano Berio , Milton Babbitt , Pierre Boulez , Luigi Nono , John Cage , György Ligeti , Iannis Xenakis , Karlheinz Stockhausen , Mauricio Kagel , and Helmut Lachenmann . The Deutsche Akademie für Sprache und Dichtung provides writers and scholars with
6237-430: The fields of electrical, mechanical and civil engineering, architecture, computer science, mathematics and the natural sciences. It also offers courses in economics, law, history, politics, sociology, psychology, sport science and linguistics. It also offers degree courses for teaching positions at German vocational schools and Gymnasiums. The Darmstadt University of Applied Sciences (German: Hochschule Darmstadt ) has
6336-454: The following elements was also confirmed at GSI Centre for Heavy Ion Research : nihonium (2012), flerovium (2009), moscovium (2012), livermorium (2010), and tennessine (2012). The Facility for Antiproton and Ion Research (FAIR) is an international accelerator facility under construction. Darmstadt is also the seat of the world's oldest pharmaceutical company, Merck , which is the city's largest employer. The Mathildenhöhe, including
6435-496: The funds available for investment were increased by Eur 600M to enable investments Biotechnology and Technology. The award was jointly established by Merck and the Technische Universität Darmstadt in 1992. It recognizes scientists who have made contributions to chemical and pharmaceutical research. During the company's 350th anniversary in 2018, Merck announced the Future Insight Prize The prize consists of
6534-526: The global Generics business being sold on 2 October 2007) paid a £12M out-of-court settlement with the Department of Health and Social Care of the UK over involvement in an alleged price and supply fixing cartel. The NHS alleges various drugs companies exploited the oligopolistic market conditions, forcing the NHS to pay inflated prices. NHS fraud investigators believe there was a conspiracy to limit
6633-540: The header and additionally displaying a disclaimer about trademark ownership in the footer. On 7 December 2021, Merck, which uses the name EMD Electronics in North America, announced they would be investing $ 1 billion in a U.S. operations joint venture with Palantir Technologies to assist in solving some of the chip industries supply chain problems. The plan is for sites in Pennsylvania, Texas, California, and Arizona. Generics UK (Merck's former British subsidiary,
6732-850: The highest number of industrial linkage programs, compared to the rest of the universities of applied sciences. The roots of University of Applied Sciences Darmstadt dates back to 1876. However, it has not emerged as a separate institution before 1971. As of 2017 it was the largest University of Applied Sciences in the State of Hesse, with about 16,000 students. It offers courses in architecture, chemical engineering, materials science, civil engineering, computer science, design, economics, electrical engineering and information technology, mathematics and science, mechanical engineering, media (including information science and engineering), plastics engineering, social and cultural studies, and several social sciences. The Protestant University of Applied Sciences Darmstadt (EHD)
6831-530: The inhabitants were killed, and 66,000 to 70,000 were left homeless. Over three-quarters of Darmstadt's inner city was destroyed. Post-war rebuilding was done in a relatively plain architectural style, although a number of the historic buildings were rebuilt to their original appearance following the city's capture on 25 March 1945 by the American 4th Armored Division . Today around 30% of Darmstadt consists out of buildings from before World War II. Throughout
6930-531: The late 1990s the Waldspirale ('Forest Spiral') was built, a residential complex by Austrian Friedensreich Hundertwasser . As an almost surreal building, it is internationally famous for its almost absolute rejection of rectangular forms, down to every window having a different shape, the style being a trademark of Hundertwasser's work. Hundertwasser died before the Waldspirale was finished. Darmstadt
7029-714: The league as the new Bezirksliga was immediately sub-divided into two independent, regional divisions. Out of the ten clubs in the league, nine went to the new Bezirksliga Main-Hessen - Main division , only the VfL Neu-Isenburg found itself grouped into the Hessen division of the new league. Qualified teams and their success: Qualified teams and their success: The league was formed from eight teams: Source: "Bezirksliga Main" . Das deutsche Fussball-Archiv . Retrieved 2008-07-26 . Darmstadt Darmstadt ( German: [ˈdaʁmʃtat] )
7128-746: The main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies globally. Merck operates in Europe , Africa , Asia , Oceania and the Americas . It has major research and development centres in Darmstadt , Boston , Tokyo and Beijing , as well as other Research and Development units in Taiwan , France , Israel , South Korea , India , and
7227-584: The main hub for German flag carrier Lufthansa . Frankfurt Egelsbach Airport ( Flugplatz Frankfurt-Egelsbach ) is a busy general aviation airport located 5 km north of Darmstadt, near the town of Egelsbach . Despite the name, Frankfurt Hahn Airport ( Flughafen Frankfurt-Hahn ) is located far outside the Frankfurt Metro Area, approximately 120 km (75 mi) to the west in Lautzenhausen ( Rhineland-Palatinate ). Hahn Airport
7326-474: The main parent company and the former a holding company . Both oHG and KGaA are generic business entity type designations and not used in everyday speech or branding. In 2015 Merck adopted a new logo to increase the visual differences between both companies, while also visualizing "vibrant science and technology" as the new company's brand. It has initiated litigation in several countries against its former subsidiary Merck & Co. (MSD) over infringing use of
7425-586: The north and Mannheim in the south. Darmstadt's southeastern boroughs are located in the spurs of the Odenwald , a low mountain range in Southern Hesse between the Main and Neckar rivers. Southern Hesse is well known for its mild climate which allows winegrowing on a large scale in the region south of Darmstadt. The weather is often volatile with the summers being warm and humid with frequent thunderstorms,
7524-671: The other runners-up of the southern Bezirksligas . The winner of this round was awarded the third entry spot for the south to the German finals. In an attempt to bring all Southern German leagues to a similar system, the Bezirksligas were reorganised in 1927. For the Bezirksliga Main , this meant, it joined with the northern clubs of the Bezirksliga Rheinhessen-Saar to form the new Bezirksliga Main-Hessen . In practice, this meant little change for
7623-535: The production of chemical and biopharmaceutical agents. In 2022 the business was restructured and consisted afterwards of the entities Life Science Services, Science & Lab Solutions, and Process Solutions. The Life Science Services include the Contract Development and Manufacturing Organization (CDMO) and contract testing services. Science & Lab Solutions includes products for Laboratories and Quality Control organizations. Process Solutions supports
7722-488: The rest of Germany and Europe through its main railway station, Darmstadt Hauptbahnhof , which is located in the western part of the city centre. The station is part of the Intercity-Express network and also served by other long-distance trains. It is a busy station with 12 platforms and serves as a transportation hub for the southern Hesse/ Odenwald region. Darmstadt Hauptbahnhof is the terminus of S3 of
7821-508: The right to award doctorates in 1899. In 1882 it was the first university in the world to set up a chair in electrical engineering, in 1883 the first faculty for electrical engineering was founded there. The university is organized in 13 departments and 5 fields of study, which all together offer about 100 courses of studies. The fields of study offer interdisciplinary degree courses in which students take lectures in multiple departments. The university, as its title suggests, offers degree courses in
7920-449: The semiconductor industry. The business unit supplies products for every major production step in the wafer processing, including doping, lithography, patterning, deposition, planarization, etching, and cleaning. After the acquisition of Intermolecular, its capabilities allow material combinations to be tested directly in the specific application environment accelerating learning cycles. Since the acquisition of Versum and Intermolecular, inc.,
8019-470: The supply of 30 of its most commonly prescribed drugs, including a class of penicillin antibiotics and to a generic version of best-selling ulcer treatment Zantac . The NHS has so far filed claims in relation to just three drugs, seeking damages of more than £150m, while the Serious Fraud Office (SFO) is conducting a parallel investigation into the price-fixing allegations limited to
8118-519: The supply of blood-thinning pill warfarin and penicillin -based antibiotics . Homes and offices of executives at six firms, including Ranbaxy , Generics UK, Norton Healthcare , Goldshield and Regent-GM were raided by the SFO in May 2002. The following is an illustration of the company's mergers, acquisitions, spin-offs and historical predecessors: After Wilhelm Adam Sertürner's isolation of morphine from opium in 1805, Merck pioneered (from 1827)
8217-563: The title of Wehrwirtschaftsführer . In addition, Merck was president of the Hessian Chamber of Commerce and Industry as well as performing an advisory function in the Expert Advisory Council for National Health ("Sachverständigenrat für Volksgesundheit ") of the Nazi Party . During World War II, Merck was manufacturing war essential products such as narcotics, vitamins, biocides and other chemicals. According to
8316-451: The war's end. The old city centre was largely destroyed in a British bombing raid on 11/12 September 1944. This attack was an example of "area bombing" using high explosive and incendiary bombs, which combined in that attack to create a firestorm, a self-sustaining combustion process in which winds generated by the fire ensure it continues to burn until everything possible has been consumed. During this attack an estimated 11,000 to 12,500 of
8415-457: The winters mostly relatively mild with frequent periods of high fog . Snowfall is most likely in January and February, but mild winters without considerable snowfall can occur. The Darmstadt weather station has recorded the following extreme values: The City of Darmstadt offers students a broad variety of public primary, secondary and tertiary schools. Besides them private schools exist, e.g.
8514-410: The world via Frankfurt Airport ( Flughafen Frankfurt am Main ) which is located 20 km (12 mi) north of central Darmstadt and connected to it via Autobahn 5, S-Bahn , several bus lines and a direct express bus-link (" Airliner "). The airport ranks among the world's busiest airports by passenger traffic and is the second-busiest airport by cargo traffic in Europe. The airport also serves as
8613-827: Was a centre of the Art Nouveau movement . Surviving examples of the Jugendstil period include the Rosenhöhe, a landscaped English-style rose garden from the 19th century, recently renovated and replanted, the UNESCO World Heritage Site Mathildenhöhe , with the Hochzeitsturm ('Wedding tower', also commonly known as the 'Five-Finger-Tower') by Joseph Maria Olbrich , the Russian Chapel in Darmstadt and large exhibition halls as well as many private villas built by Jugendstil architects who had settled in Darmstadt. German Art Nouveau
8712-444: Was adopted as the most common German-language term for the style: Jugendstil ("young style"). Although, during the early 20th century, the word was applied to only two-dimensional examples of the graphic arts, especially the forms of organic typography and graphic design found in and influenced by German magazines like Jugend, Pan, and Simplicissimus , it is now applied to more general manifestations of Art Nouveau visual arts in Germany,
8811-458: Was also preparing a bid for the division in the region of €4 billion ($ 4.7 billion to $ 4.8 billion). In April 2018, Reuters reported that generic drug manufacturer, Mylan was in advanced discussions to acquire the consumer health business for between €3.5–4 billion (£3–3.4 billion). Later in the month, Reuters reported that Procter & Gamble would purchase the division for €3.4 billion euros (£2.96 billion; $ 4.2 billion). Merck in Darmstadt
8910-576: Was announced that the company would acquire Sigma-Aldrich for $ 17 billion. After the acquisition was completed in 2015, Merck had around 50,000 employees. In November 2014, Merck and Pfizer agreed a deal for the latter to sell the former sharing rights to develop an experimental immunotherapy drug for a fee of $ 850 million. In October 2015, Merck revealed it would return the rights of the Kuvan drug to BioMarin Pharmaceutical Inc. The drug
9009-555: Was chartered as a city by the Holy Roman Emperor Ludwig the Bavarian in 1330, at which time it belonged to the counts of Katzenelnbogen . The city, then called Darmstait , became a secondary residence for the counts, with a small castle established at the site of the current, much larger edifice. When the house of Katzenelnbogen became extinct in 1479, the city was passed to the Landgraviate of Hesse , and
9108-748: Was completed in October 2019 and represented an equity value of about U$ 5.8 billion. In the same year, Merck has also announced the acquisition of Intermolecular Inc, the California-based company for advanced materials. The acquisition was completed in September 2019 and represented an equity value of U$ 62 million. In February 2020, Merck announced the divestment of its Allergopharma Business to Dermapharm, under an unspecified fee. The deal includes Merck's Portfolio in Europe and parts of Asia, including China and India. In January 2021, MilliporeSigma announced it would acquire AmpTec to expand and enhance
9207-537: Was created in July 2010 following the completed acquisition of the US company Millipore. It employs around 19,000 people in 66 countries and runs 65 manufacturing sites and uses the brands Sigma-Aldrich, Milli-Q and Millipore. This division comprises all Millipore activities and major segments of the former Merck division Performance & Life Science Chemicals.Merck Millipore had three business units: Bioscience, Lab Solutions and Process Solutions. The Bioscience business unit
9306-465: Was held on 14 March 2021, and the results were as follows: Darmstadt is connected to a number of major roads, including two Autobahnen ( Bundesautobahn 5 and Bundesautobahn 67 ). The main road passing west–east is the Bundesstraße 26 , the Bundesstraße 3 runs north–south. The rural areas east of the city in the Odenwald are accessed by several secondary roads. Darmstadt is connected to
9405-689: Was part of the Royal Gardens used exclusively by the dukes of Darmstadt. Today it is a public park, heavily used in every season of the year. Other important parks are the French style parks Prinz-Georgs-Garten and Orangerie , the modern style Bürgerpark ("People's Park") in northern Darmstadt and the mystical Park Rosenhöhe ("Rose Heights"), which also serves as the cemetery for the dukes and their immediate family, with two impressive mausoleum buildings (Altes Mausoleum and Neues Mausoleum) in its remote parts. The Botanischer Garten in eastern Darmstadt
9504-637: Was placed in the middle of the square. While the column still stands, the square is today surrounded by mostly modern buildings. Other important squares are the Marktplatz (see image) near the old city hall and the Sabaisplatz at the Mathildenhöhe . The city has a high density of parks. Among the most important parks are the English style Herrngarten in central Darmstadt. In former times it
9603-432: Was seat of the ruling landgraves (1567–1806) and thereafter (to 1918) of the grand dukes of Hesse . The city's population grew during the 19th century, from a little over 10,000, to 72,000 inhabitants. A polytechnical school, which later became a Technical University now known as TU Darmstadt , was established in 1877. In the early 20th century, Darmstadt was an important centre for the art movement of Jugendstil ,
9702-466: Was the first city in Germany to force Jewish shops to close in early 1933, shortly after the Nazis took power in Germany. The shops were only closed for one day, for "endangering communal order and tranquility". In 1942, over 3,000 Jews from Darmstadt were first forced into a collection camp located in the Liebigschule, and later deported to concentration camps where most eventually died. In 1944,
9801-720: Was the only official Russian church used by the Tsar outside the Russian Empire . It is said that the chapel was built on Russian soil that was brought to Darmstadt exclusively for the purpose of building the Tsar's private chapel on it. Every year on the first weekend of July the Heinerfest festival is held in the streets surrounding the old ducal palace. It is a traditional German festival with music acts, beer halls , amusement rides and booths selling trinkets and food. The similar Schlossgrabenfest [ de ] , which
#782217