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Japanese Pharmacopoeia

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135-504: The Japanese Pharmacopoeia ( 日本薬局方 ) is the official pharmacopoeia of Japan . It is published by the Pharmaceuticals and Medical Devices Agency ( 独立行政法人 医薬品医療機器総合機構 , Dokuritsu-gyōsei hōjin iyakuhin-iryō-kiki-sōgō-kikō ) . The first edition was published on 25 June 1886, with revisions being issued from time to time. The current revision is number 18, issued electronically on 7 June 2021. An official English translation

270-577: A failed war in northern Korea provoked widespread unrest. Under the succeeding Tang and Song dynasties , Chinese economy, technology, and culture entered a golden age. The Tang dynasty retained control of the Western Regions and the Silk Road, which brought traders to as far as Mesopotamia and the Horn of Africa , and made the capital Chang'an a cosmopolitan urban center. However, it

405-401: A climate very suitable for agriculture and the country has been the world's largest producer of rice, wheat, tomatoes, eggplant, grapes, watermelon, spinach, and many other crops. In 2021, 12 percent of global permanent meadows and pastures belonged to China, as well as 8% of global cropland. China is one of 17 megadiverse countries , lying in two of the world's major biogeographic realms :

540-464: A commercial standard of purity as distinct from a medicinal one is needed, since the preparations used in medicine should be of the highest possible degree of purity obtainable, and this standard would be too high and too expensive for ordinary purposes. The use of trade synonyms in the Pharmacopoeia, such as saltpetre for purified potassium nitrate , and milk of sulphur for precipitated sulphur,

675-524: A common monograph that provides a common set of tests and specifications for a specific material. This is a slow process. The World Health Organization has produced the International Pharmacopoeia (Ph.Int.), which does not replace a national pharmacopoeia but rather provides a model or template for one and also can be invoked by legislation within a country to serve as that country's regulation. Though formerly printed there has been

810-532: A cultural identity among its populace still remembered in the ethnonym of the modern Han Chinese . The Han expanded the empire's territory considerably , with military campaigns reaching Central Asia, Mongolia , Korea , and Yunnan , and the recovery of Guangdong and northern Vietnam from Nanyue . Han involvement in Central Asia and Sogdia helped establish the land route of the Silk Road , replacing

945-634: A disputed land border with India and Bhutan . China is additionally involved in maritime disputes with multiple countries over territory in the East and South China Seas , such as the Senkaku Islands and the entirety of South China Sea Islands . The People's Republic of China is a one-party state governed by the Chinese Communist Party (CCP). The CCP is officially guided by socialism with Chinese characteristics , which

1080-730: A far-reaching popular uprising (the May Fourth Movement ). In the late 1920s, the Kuomintang under Chiang Kai-shek was able to reunify the country under its own control with a series of deft military and political maneuverings known collectively as the Northern Expedition . The Kuomintang moved the nation's capital to Nanjing and implemented "political tutelage", an intermediate stage of political development outlined in Sun Yat-sen's Three Principles of

1215-475: A high density of plant species including numerous rare endemics. Tropical and seasonal rainforests , though confined to Yunnan and Hainan , contain a quarter of all the animal and plant species found in China. China has over 10,000 recorded species of fungi . In the early 2000s, China has suffered from environmental deterioration and pollution due to its rapid pace of industrialization. Regulations such as

1350-536: A large number of simples were used in consequence of the same substance being supposed to possess different qualities according to the source from which it was derived. Thus crabs' eyes (i.e., gastroliths ), pearls, oyster shells, and coral were supposed to have different properties. Among other ingredients entering into some of these formulae were the excrements of human beings, dogs, mice, geese, and other animals, calculi , human skull, and moss growing on it, blind puppies, earthworms , etc. Although other editions of

1485-547: A legal standard for the drugs and preparations contained in it. The Pharmacopoeia is defined in the preface as only "intended to afford to the members of the medical profession and those engaged in the preparation of medicines throughout the British Empire one uniform standard and guide whereby the nature and composition of, substances to be used in medicine may be ascertained and determined". It cannot be an encyclopaedia of substances used in medicine, and can be used only as

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1620-497: A major focus, special economic zones (SEZs) were created. Inefficient state-owned enterprises (SOEs) were restructured and some closed. This marked China's transition away from planned economy. China adopted its current constitution on 4 December 1982. In 1989, there were protests such those in Tiananmen Square , and then throughout the entire nation. Zhao Ziyang was put under house arrest for his sympathies to

1755-404: A permanent navy which was supported by the developed shipbuilding industry along with the sea trade. Between the 10th and 11th century CE, the population of China doubled to around 100 million people, mostly because of the expansion of rice cultivation in central and southern China, and the production of abundant food surpluses. The Song dynasty also saw a revival of Confucianism , in response to

1890-770: A result, the Medical Act of 1858 ordained that the General Medical Council should publish a book containing a list of medicines and compounds, to be called the British Pharmacopoeia , which would be a substitute throughout Great Britain and Ireland for the separate pharmacopoeias. Hitherto these had been published in Latin. The first British Pharmacopoeia was published in the English language in 1864, but gave such general dissatisfaction both to

2025-579: A standard for the substances and preparations contained in it, and for no others. It has been held in the Divisional Courts (Dickins v. Randerson) that the Pharmacopoeia is a standard for official preparations asked for under their pharmacopoeial name. But there are many substances in the Pharmacopoeia which are not only employed in medicine, but have other uses, such as sulphur , gum benzoin , tragacanth , gum arabic , ammonium carbonate , beeswax , oil of turpentine , linseed oil , and for these

2160-643: A transition to a situation where pharmaceutical information is available as printed volumes and on the internet . The rapid increase in knowledge renders necessary frequent new editions, to furnish definite formulae for preparations that have already come into extensive use in medical practice, so as to ensure uniformity of strength, and to give the characters and tests by which their purity and potency may be determined. However each new edition requires several years to carry out numerous experiments for devising suitable formulae, so that current pharmacopoeia are never quite up to date. This difficulty has hitherto been met by

2295-457: Is Marxism adapted to Chinese circumstances . The Chinese constitution states that the PRC "is a socialist state governed by a people's democratic dictatorship that is led by the working class and based on an alliance of workers and peasants," that the state institutions "shall practice the principle of democratic centralism ," and that "the defining feature of socialism with Chinese characteristics

2430-609: Is "China" ( 中国 ; 中國 ; Zhōngguó ), from zhōng ('central') and guó ('state'), a term which developed under the Western Zhou dynasty in reference to its royal demesne . It was used in official documents as an synonym for the state under the Qing . The name Zhongguo is also translated as 'Middle Kingdom' in English. China is sometimes referred to as " mainland China " or "the Mainland" when distinguishing it from

2565-587: Is an applicable USP-NF quality monograph, drugs and drug ingredients must conform to the compendial requirements (such as for strength, quality or purity) or be deemed adulterated or misbranded under the Federal food and drug laws. The Soviet Union had a nominally supranational pharmacopoeia, the State Pharmacopoeia of the Union of Soviet Socialist Republics (USSRP), although the de facto nature of

2700-856: Is bounded by the Bohai , Yellow , East China and South China seas. China connects through the Kazakh border to the Eurasian Steppe . The territory of China lies between latitudes 18° and 54° N , and longitudes 73° and 135° E . The geographical center of China is marked by the Center of the Country Monument at 35°50′40.9″N 103°27′7.5″E  /  35.844694°N 103.452083°E  / 35.844694; 103.452083  ( Geographical center of China ) . China's landscapes vary significantly across its vast territory. In

2835-550: Is common. China China , officially the People's Republic of China ( PRC ), is a country in East Asia . With a population exceeding 1.4 billion, it is the second-most populous country after India , representing 17.4% of the world population. China spans the equivalent of five time zones and borders fourteen countries by land . With an area of nearly 9.6 million square kilometers (3,700,000 sq mi), it

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2970-585: Is commonly agreed that pre-modern China's population experienced two growth spurts, one during the Northern Song period (960–1127), and other during the Qing period (around 1700–1830). By the High Qing era China was possibly the most commercialized country in the world, and imperial China experienced a second commercial revolution by the end of the 18th century. On the other hand, the centralized autocracy

3105-461: Is home to a variety of forest types. Cold coniferous forests predominate in the north of the country, supporting animal species such as moose and Asian black bear , along with over 120 bird species. The understory of moist conifer forests may contain thickets of bamboo . In higher montane stands of juniper and yew , the bamboo is replaced by rhododendrons . Subtropical forests, which are predominate in central and southern China, support

3240-421: Is in preparation (status: 06 Aug 2021). This Japanese literature–related article is a stub . You can help Misplaced Pages by expanding it . Pharmacopoeia A pharmacopoeia , pharmacopeia , or pharmacopoea (from the obsolete typography pharmacopœia , meaning "drug-making"), in its modern technical sense, is a book containing directions for the identification of compound medicines , and published by

3375-626: Is no standard of purity that can be used under the Adulteration of Food and Drugs Act, and for these, as well as for the commercial quality of those drugs and essential oils which are also in the Pharmacopoeia, a legal standard of commercial purity is much needed. This subject formed the basis of discussion at several meetings of the Pharmaceutical Society, and the results have been embodied in a work called Suggested Standards for Foods and Drugs by C. G. Moor, which indicates

3510-411: Is partly answerable for this difficulty, and has proved to be a mistake, since it affords ground for legal prosecution if a chemist sells a drug of ordinary commercial purity for trade purposes, instead of the purified preparation which is official in the Pharmacopoeia for medicinal use. This would not be the case if the trade synonym were omitted. For many drugs and chemicals not in the Pharmacopoeia there

3645-451: Is protected by law, and as of 2005 , the country has over 2,349 nature reserves , covering a total area of 149.95 million hectares, 15 percent of China's total land area. Most wild animals have been eliminated from the core agricultural regions of east and central China, but they have fared better in the mountainous south and west. The Baiji was confirmed extinct on 12 December 2006. China has over 32,000 species of vascular plants, and

3780-422: Is the third-largest country by total land area. The country is divided into 33 province-level divisions : 22 provinces , five autonomous regions , four municipalities , and two semi-autonomous special administrative regions . Beijing is the country's capital, while Shanghai is its most populous city by urban area and largest financial center . China is considered one of the cradles of civilization :

3915-451: Is the direct ancestor of modern Chinese characters . The Shang were overthrown by the Zhou , who ruled between the 11th and 5th centuries BCE, though the centralized authority of Son of Heaven was slowly eroded by fengjian lords. Some principalities eventually emerged from the weakened Zhou and continually waged war with each other during the 300-year Spring and Autumn period . By

4050-661: Is the earliest known Chinese pharmacopoeia. The text describes 365 medicines derived from plants, animals, and minerals; according to legend it was written by the Chinese god Shennong . Pharmacopeial synopsis were recorded in the Timbuktu manuscripts of Mali . The earliest extant Chinese pharmacopoeia, the Shennong Ben Cao Jing was compiled between 200-250 AD. It contains descriptions of 365 medications. The earliest known officially sponsored pharmacopoeia

4185-401: Is the leadership of the Chinese Communist Party." The PRC officially terms itself as a democracy , using terms such as "socialist consultative democracy", and " whole-process people's democracy ". However, the country is commonly described as an authoritarian one-party state and a dictatorship , with among the heaviest restrictions worldwide in many areas, most notably against freedom of

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4320-559: Is the world's leading investor in renewable energy and its commercialization , with $ 546 billion invested in 2022; it is a major manufacturer of renewable energy technologies and invests heavily in local-scale renewable energy projects. Long heavily relying on non-renewable energy sources such as coal, China's adaptation of renewable energy has increased significantly in recent years, with their share increasing from 26.3 percent in 2016 to 31.9 percent in 2022. In 2023, 60.5% of China's electricity came from coal (largest producer in

4455-702: The Encyclopædia Britannica , to 9,596,961 km (3,705,407 sq mi) according to the UN Demographic Yearbook , and The World Factbook . China has the longest combined land border in the world , measuring 22,117 km (13,743 mi) and its coastline covers approximately 14,500 km (9,000 mi) from the mouth of the Yalu River (Amnok River) to the Gulf of Tonkin . China borders 14 nations and covers

4590-456: The 18th CCP National Congress in 2012. Shortly after his ascension to power, Xi launched a vast anti-corruption crackdown , that prosecuted more than 2 million officials by 2022. During his tenure , Xi has consolidated power unseen since the initiation of economic and political reforms. China's landscape is vast and diverse, ranging from the Gobi and Taklamakan Deserts in the arid north to

4725-469: The Antidotarium of Nicolaus de Salerno , containing Galenic formulations arranged alphabetically. Of this last work, there were two editions in use — Nicolaus magnus and Nicolaus parvus: in the latter, several of the compounds described in the large edition were omitted and the formulae given on a smaller scale. Also Vesalius claimed he had written some " dispensariums " and " manuals " on

4860-827: The Antidotarium Florentinum , was published under the authority of the college of medicine of Florence in the 16th century. In 1511, the Concordie Apothecariorum Barchinone was published by the Society of Apothecaries of Barcelona and kept in the School of Pharmacy of the University of Barcelona . The term Pharmacopoeia first appears as a distinct title in a work published at Basel , Switzerland, in 1561 by A. Foes, but does not appear to have come into general use until

4995-621: The British Empire . As regards the purely pharmaceutical part of the work a committee of reference in pharmacy, nominated by the pharmaceutical societies of Great Britain and Ireland (as they were then), was appointed to report to the Pharmacopoeia Committee of the Medical Council. Some difficulty has arisen since the passing of the Adulteration of Food and Drugs Act concerning the use of the Pharmacopoeia as

5130-778: The Cultural Revolution , sparking a decade of political recrimination and social upheaval that lasted until Mao's death in 1976. In October 1971, the PRC replaced the ROC in the United Nations, and took its seat as a permanent member of the Security Council. After Mao's death, the Gang of Four was arrested by Hua Guofeng and held responsible for the Cultural Revolution. The Cultural Revolution

5265-589: The International Society for the History of Medicine , with agreement of John M. Riddle , one of the foremost experts on Materia Medica - Dioscorides works. Nicolaes Tulp , mayor of Amsterdam and respected surgeon general, gathered all of his doctor and chemist friends together and they wrote the first pharmacopoeia of Amsterdam named Pharmacopoea Amstelredamensis in 1636. This was a combined effort to improve public health after an outbreak of

5400-636: The Kuomintang and the Communists led to the resumption of civil war. Constitutional rule was established in 1947, but because of the ongoing unrest, many provisions of the ROC constitution were never implemented in mainland China. Afterwards, the CCP took control of most of mainland China, and the ROC government retreated offshore to Taiwan . On 1 October 1949, CCP Chairman Mao Zedong formally proclaimed

5535-568: The Northern Chinese Famine of 1876–1879 , in which between 9 and 13 million people died. The Guangxu Emperor drafted a reform plan in 1898 to establish a modern constitutional monarchy , but these plans were thwarted by the Empress Dowager Cixi . The ill-fated anti-foreign Boxer Rebellion of 1899–1901 further weakened the dynasty. Although Cixi sponsored a program of reforms known as the late Qing reforms ,

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5670-620: The Palearctic and the Indomalayan . By one measure, China has over 34,687 species of animals and vascular plants, making it the third-most biodiverse country in the world, after Brazil and Colombia . The country is a party to the Convention on Biological Diversity ; its National Biodiversity Strategy and Action Plan was received by the convention in 2010. China is home to at least 551 species of mammals (the third-highest in

5805-744: The RCEP . It is a member of the BRICS , the G20 , APEC , the SCO , and the East Asia Summit . Making up around one-fifth of the world economy, the Chinese economy is the world's largest economy by PPP-adjusted GDP , the second-largest economy by nominal GDP , and the second-wealthiest country , albeit ranking poorly in measures of democracy , human rights and religious freedom . The country has been one of

5940-784: The Republic of China or the PRC's Special Administrative Regions . Archaeological evidence suggests that early hominids inhabited China 2.25 million years ago. The hominid fossils of Peking Man , a Homo erectus who used fire , have been dated to between 680,000 and 780,000 years ago . The fossilized teeth of Homo sapiens (dated to 125,000–80,000 years ago) have been discovered in Fuyan Cave . Chinese proto-writing existed in Jiahu around 6600 BCE, at Damaidi around 6000 BCE, Dadiwan from 5800 to 5400 BCE, and Banpo dating from

6075-700: The Second United Front to fight the Japanese. The Second Sino-Japanese War eventually ended in a Chinese victory; however, the CCP and the KMT resumed their civil war as soon as the war ended. In 1949, the resurgent Communists established control over most of the country, proclaiming the People's Republic of China and forcing the Nationalist government to retreat to the island of Taiwan . The country

6210-594: The Sino-Soviet split , the Shanghai Communiqué in 1972 would precipitate the normalization of relations with the United States . Economic reforms that began in 1978 moved the country away from a socialist planned economy towards an increasingly capitalist market economy , spurring significant economic growth. The corresponding movement for increased democracy and liberalization stalled after

6345-476: The State Council , China's cabinet, composed of four vice premiers, state councilors , and the heads of ministries and commissions. The Chinese People's Political Consultative Conference (CPPCC) is a political advisory body that is critical in China's " united front " system, which aims to gather non-CCP voices to support the CCP. Similar to the people's congresses, CPPCC's exist at various division, with

6480-723: The Tiananmen Square protests and massacre in 1989. China is a unitary one-party socialist republic led by the CCP. It is one of the five permanent members of the UN Security Council ; the UN representative for China was changed from the ROC to the PRC in 1971. It is a founding member of several multilateral and regional organizations such as the AIIB , the Silk Road Fund , the New Development Bank , and

6615-438: The Turpan Depression . China's climate is mainly dominated by dry seasons and wet monsoons , which lead to pronounced temperature differences between winter and summer. In the winter, northern winds coming from high-latitude areas are cold and dry; in summer, southern winds from coastal areas at lower latitudes are warm and moist. A major environmental issue in China is the continued expansion of its deserts , particularly

6750-481: The World Trade Organization in 2001. At the 16th CCP National Congress in 2002, Hu Jintao succeeded Jiang as the general secretary. Under Hu, China maintained its high rate of economic growth, overtaking the United Kingdom, France, Germany and Japan to become the world's second-largest economy. However, the growth also severely impacted the country's resources and environment, and caused major social displacement. Xi Jinping succeeded Hu as paramount leader at

6885-433: The Xi , Mekong , Brahmaputra and Amur . To the west sit major mountain ranges, most notably the Himalayas. High plateaus feature among the more arid landscapes of the north, such as the Taklamakan and the Gobi Desert. The world's highest point, Mount Everest (8,848 m), lies on the Sino-Nepalese border. The country's lowest point, and the world's third-lowest, is the dried lake bed of Ayding Lake (−154 m) in

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7020-426: The Xinhai Revolution of 1911–1912 ended the Qing dynasty and established the Republic of China . Puyi , the last Emperor, abdicated in 1912 . On 1 January 1912, the Republic of China was established, and Sun Yat-sen of the Kuomintang (KMT) was proclaimed provisional president. In March 1912, the presidency was given to Yuan Shikai , a former Qing general who in 1915 proclaimed himself Emperor of China . In

7155-400: The bubonic plague , and also to limit the number of quack apothecary shops in Amsterdam. Until 1617, such drugs and medicines as were in common use were sold in England by the apothecaries and grocers. In that year the apothecaries obtained a separate charter, and it was enacted that no grocer should keep an apothecary's shop. The preparation of physicians' prescriptions was thus confined to

7290-422: The campaigns against Western Xia by Genghis Khan , who also invaded Jin territories . In 1271, the Mongol leader Kublai Khan established the Yuan dynasty , which conquered the last remnant of the Song dynasty in 1279. Before the Mongol invasion, the population of Song China was 120 million citizens; this was reduced to 60 million by the time of the census in 1300. A peasant named Zhu Yuanzhang overthrew

7425-438: The fastest-growing major economies and is the world's largest manufacturer and exporter , as well as the second-largest importer . China is a nuclear-weapon state with the world's largest standing army by military personnel and the second-largest defense budget . It is a great power , and has been described as an emerging superpower . China is known for its cuisine and culture, and has 59 UNESCO World Heritage Sites ,

7560-399: The second-highest number of any country . The word "China" has been used in English since the 16th century; however, it was not used by the Chinese themselves during this period. Its origin has been traced through Portuguese , Malay , and Persian back to the Sanskrit word Cīna , used in ancient India . "China" appears in Richard Eden 's 1555 translation of the 1516 journal of

7695-422: The subtropical forests in the wetter south. The Himalaya , Karakoram , Pamir and Tian Shan mountain ranges separate China from much of South and Central Asia . The Yangtze and Yellow Rivers, the third- and sixth-longest in the world, respectively, run from the Tibetan Plateau to the densely populated eastern seaboard. China's coastline along the Pacific Ocean is 14,500 km (9,000 mi) long and

7830-440: The 1979 Environmental Protection Law are fairly stringent, though they are poorly enforced, frequently disregarded in favor of rapid economic development. China has the second-highest death toll because of air pollution, after India , with approximately 1 million deaths. Although China ranks as the highest CO 2 emitting country, it only emits 8 tons of CO 2 per capita , significantly lower than developed countries such as

7965-406: The 2010s. In 2020, the Chinese government announced its aims for the country to reach its peak emissions levels before 2030, and achieve carbon neutrality by 2060 in line with the Paris Agreement , which, according to Climate Action Tracker , would lower the expected rise in global temperature by 0.2–0.3 degrees – "the biggest single reduction ever estimated by the Climate Action Tracker". China

8100-405: The 5th millennium BCE. Some scholars have suggested that the Jiahu symbols (7th millennium BCE) constituted the earliest Chinese writing system. According to traditional Chinese historiography , the Xia dynasty was established during the late 3rd millennium BCE, marking the beginning of the dynastic cycle that was understood to underpin China's entire political history. In the modern era,

8235-416: The British under the 1842 Treaty of Nanking , the first of what have been termed as the " unequal treaties ". The First Sino-Japanese War (1894–1895) resulted in Qing China's loss of influence in the Korean Peninsula , as well as the cession of Taiwan to Japan . The Qing dynasty also began experiencing internal unrest in which tens of millions of people died, especially in the White Lotus Rebellion ,

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8370-441: The British Pharmacopoeia in 1898. A committee of the Royal Pharmaceutical Society of Great Britain was appointed at the request of the General Medical Council to advise on pharmaceutical matters. A census of prescriptions was taken to ascertain the relative frequency with which different preparations and drugs were used in prescriptions, and suggestions and criticisms were sought from various medical and pharmaceutical bodies across

8505-400: The CCP. The NPC is dominated by the CCP, with another eight minor parties having nominal representation under the condition of upholding CCP leadership. The president is elected by the NPC. The presidency is the ceremonial state representative, but not the constitutional head of state. The incumbent president is Xi Jinping, who is also the general secretary of the CCP and the chairman of

8640-413: The Central Military Commission , making him China's paramount leader and supreme commander of the Armed Forces. The premier is the head of government , with Li Qiang being the incumbent. The premier is officially nominated by the president and then elected by the NPC, and has generally been either the second- or third-ranking member of the Politburo Standing Committee (PSC). The premier presides over

8775-405: The EU. In the U.S., the USP-NF (United States Pharmacopeia – National Formulary) has been issued by a private non-profit organization since 1820 under the authority of a Convention that meets periodically that is largely constituted by physicians, pharmacists, and other public health professionals, setting standards published in the compendia through various Expert Committees. In the U.S. when there

8910-450: The Gobi Desert. Although barrier tree lines planted since the 1970s have reduced the frequency of sandstorms , prolonged drought and poor agricultural practices have resulted in dust storms plaguing northern China each spring, which then spread to other parts of East Asia, including Japan and Korea. Water quality, erosion , and pollution control have become important issues in China's relations with other countries. Melting glaciers in

9045-668: The Himalayas could potentially lead to water shortages for hundreds of millions of people. According to academics, in order to limit climate change in China to 1.5 °C (2.7 °F) electricity generation from coal in China without carbon capture must be phased out by 2045. With current policies, the GHG emissions of China will probably peak in 2025, and by 2030 they will return to 2022 levels. However, such pathway still leads to three-degree temperature rise. Official government statistics about Chinese agricultural productivity are considered unreliable, due to exaggeration of production at subsidiary government levels. Much of China has

9180-430: The Kuomintang and the CCP. Japanese forces committed numerous war atrocities against the civilian population; as many as 20 million Chinese civilians died. An estimated 40,000 to 300,000 Chinese were massacred in Nanjing alone during the Japanese occupation. China, along with the UK, the United States, and the Soviet Union , were recognized as the Allied " Big Four " in the Declaration by United Nations . Along with

9315-427: The London Pharmacopoeia were issued in 1621, 1632, 1639, and 1677, it was not until the edition of 1721, published under the auspices of Sir Hans Sloane , that any important alterations were made. In this issue many of the remedies previously in use were omitted, although a good number were still retained, such as dogs' excrement, earthworms, and moss from the human skull; the botanical names of herbal remedies were for

9450-580: The PRC initially allied closely with the Soviet Union , the relations between the two communist nations gradually deteriorated , leading China to develop an independent industrial system and its own nuclear weapons . The Chinese population increased from 550 million in 1950 to 900 million in 1974. However, the Great Leap Forward , an idealistic massive industrialization project, resulted in an estimated 15 to 55 million deaths between 1959 and 1961, mostly from starvation. In 1964, China detonated its first atomic bomb. In 1966, Mao and his allies launched

9585-497: The People program for transforming China into a modern democratic state. The Kuomintang briefly allied with the Chinese Communist Party (CCP) during the Northern Expedition, though the alliance broke down in 1927 after Chiang violently suppressed the CCP and other leftists in Shanghai, marking the beginning of the Chinese Civil War . The CCP declared areas of the country as the Chinese Soviet Republic (Jiangxi Soviet) in November 1931 in Ruijin , Jiangxi . The Jiangxi Soviet

9720-535: The People's Republic of China in Tiananmen Square , Beijing . In 1950, the PRC captured Hainan from the ROC and annexed Tibet . However, remaining Kuomintang forces continued to wage an insurgency in western China throughout the 1950s. The CCP consolidated its popularity among the peasants through the Land Reform Movement , which included the state-tolerated executions of between 1 and 2 million landlords by peasants and former tenants. Though

9855-457: The Pharmacopoeia is shown by the fact that they are even more largely used than the Pharmacopoeia itself, the first issued in 18 editions and the second in 13 editions at comparatively short intervals. In the UK, the task of elaborating a new Pharmacopoeia is entrusted to a body of a purely medical character, and legally the pharmacist does not, contrary to the practice in other countries, have a voice in

9990-573: The Portuguese explorer Duarte Barbosa . Barbosa's usage was derived from Persian Chīn ( چین ), which in turn derived from Sanskrit Cīna ( चीन ). Cīna was first used in early Hindu scripture, including the Mahabharata (5th century BCE) and the Laws of Manu (2nd century BCE). In 1655, Martino Martini suggested that the word China is derived ultimately from

10125-488: The United States (16.1), Australia (16.8) and South Korea (13.6). Greenhouse gas emissions by China are the world's largest . The country has significant water pollution problems; only 89.4% of China's national surface water was graded suitable for human consumption by the Ministry of Ecology and Environment in 2023. China has prioritized clamping down on pollution, bringing a significant decrease in air pollution in

10260-556: The Xia is the earliest for which there are both contemporary written records and undisputed archaeological evidence. The Shang ruled much of the Yellow River valley until the 11th century BCE, with the earliest hard evidence dated c.  1300 BCE . The oracle bone script , attested from c.  1250 BCE but generally assumed to be considerably older, represents the oldest known form of written Chinese , and

10395-513: The Xia's historicity came under increasing scrutiny, in part due to the earliest known attestation of the Xia being written millennia after the date given for their collapse. In 1958, archaeologists discovered sites belonging to the Erlitou culture that existed during the early Bronze Age ; they have since been characterized as the remains of the historical Xia, but this conception is often rejected. The Shang dynasty that traditionally succeeded

10530-681: The Yuan in 1368 and founded the Ming dynasty as the Hongwu Emperor . Under the Ming dynasty, China enjoyed another golden age, developing one of the strongest navies in the world and a rich and prosperous economy amid a flourishing of art and culture. It was during this period that admiral Zheng He led the Ming treasure voyages throughout the Indian Ocean, reaching as far as East Africa. In

10665-402: The anonymous " Dispensarium or Enquiridion " in 1543, at Lyon , France, with Jean Frellon as editor. This work contains 224 original recipes by De Villeneuve and others by Lespleigney and Chappuis. As usual when it comes to pharmacopoeias, this work was complementary to a previous Materia Medica that De Villeneuve published that same year. This finding was communicated by the same scholar in

10800-589: The apothecaries, upon whom pressure was brought to bear to make them dispense accurately, by the issue of a pharmacopoeia in May 1618 by the College of Physicians , and by the power which the wardens of the apothecaries received in common with the censors of the College of Physicians of examining the shops of apothecaries within 7 m. of London and destroying all the compounds which they found unfaithfully prepared. This,

10935-470: The authority of a government or a medical or pharmaceutical society. Descriptions of preparations are called monographs . In a broader sense it is a reference work for pharmaceutical drug specifications . The term derives from Ancient Greek : φαρμακοποιία , romanized :  pharmakopoiia "making of (healing) medicine, drug-making", a compound of "medicine, drug, poison" ( Ancient Greek : φάρμακον , romanized :  pharmakon ), with

11070-548: The average degree of purity of many drugs and chemicals used in the arts, as well as the highest degree of purity obtainable in commerce of those used in medicine. An important step has also been taken in this direction by the publication under the authority of the Council of the Pharmaceutical Society of Great Britain of the British Pharmaceutical Codex (BPC), in which the characters of and tests for

11205-935: The banner of the International Council on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), a tri-regional organisation that represents the drug regulatory authorities of the European Union , Japan , and the United States . Representatives from the Pharmacopoeias of these three regions have met twice yearly since 1990 in the Pharmacopoeial Discussion Group to try to work towards "compendial harmonisation". Specific monographs are proposed, and if accepted, proceed through stages of review and consultation leading to adoption of

11340-536: The beginning of the 17th century. Before 1542, the works principally used by apothecaries were the treatises on simples (basic medicinal ingredients) by Avicenna and Serapion ; the De synonymis and Quid pro quo of Simon Januensis ; the Liber servitoris of Bulchasim Ben Aberazerim , which described preparations made from plants, animals, and minerals, and was the type of the chemical portion of modern pharmacopoeias; and

11475-820: The bulk of East Asia, bordering Vietnam , Laos , and Myanmar in Southeast Asia; India , Bhutan , Nepal , Pakistan and Afghanistan in South Asia; Tajikistan , Kyrgyzstan and Kazakhstan in Central Asia; and Russia, Mongolia , and North Korea in Inner Asia and Northeast Asia . It is narrowly separated from Bangladesh and Thailand to the southwest and south, and has several maritime neighbors such as Japan , Philippines , Malaysia , and Indonesia . China has resolved its land borders with 12 out of 14 neighboring countries, having pursued substantial compromises in most of them. China currently has

11610-401: The commercial grade of purity of those in the Pharmacopoeia which are used for non-medical purposes. Another legal difficulty connected with modern pharmacopoeias is the inclusion in some of them of synthetic chemical remedies, the processes for preparing which have been patented, whilst the substances are sold under trade-mark names. The scientific chemical name is often long and unwieldy, and

11745-459: The construction of a pharmacopoeia is now fully recognized in other countries, in most of which pharmaceutical chemists are represented on the committee for the preparation of the legally recognized manuals. There are national and international pharmacopoeias, like the EU and the U.S. pharmacopoeias. The pharmacopeia in the EU is prepared by a governmental organization, and has a specified role in law in

11880-462: The country in the late 19th century to various European powers by a series of unequal treaties . After decades of Qing China on the decline, the 1911 Revolution overthrew the Qing dynasty and the monarchy and the Republic of China (ROC) was established the following year. The country under the nascent Beiyang government was unstable and ultimately fragmented during the Warlord Era , which

12015-610: The earlier path over the Himalayas to India. Han China gradually became the largest economy of the ancient world. Despite the Han's initial decentralization and the official abandonment of the Qin philosophy of Legalism in favor of Confucianism , Qin's legalist institutions and policies continued to be employed by the Han government and its successors. After the end of the Han dynasty , a period of strife known as Three Kingdoms followed, at

12150-537: The early Ming dynasty, China's capital was moved from Nanjing to Beijing. With the budding of capitalism, philosophers such as Wang Yangming critiqued and expanded Neo-Confucianism with concepts of individualism and equality of four occupations . The scholar-official stratum became a supporting force of industry and commerce in the tax boycott movements, which, together with the famines and defense against Japanese invasions of Korea (1592–1598) and Later Jin incursions led to an exhausted treasury. In 1644, Beijing

12285-737: The east, along the shores of the Yellow Sea and the East China Sea, there are extensive and densely populated alluvial plains , while on the edges of the Inner Mongolian plateau in the north, broad grasslands predominate. Southern China is dominated by hills and low mountain ranges, while the central-east hosts the deltas of China's two major rivers, the Yellow River and the Yangtze River. Other major rivers include

12420-656: The end of which Wei was swiftly overthrown by the Jin dynasty . The Jin fell to civil war upon the ascension of a developmentally disabled emperor ; the Five Barbarians then rebelled and ruled northern China as the Sixteen States . The Xianbei unified them as the Northern Wei , whose Emperor Xiaowen reversed his predecessors' apartheid policies and enforced a drastic sinification on his subjects . In

12555-473: The face of popular condemnation and opposition from his own Beiyang Army , he was forced to abdicate and re-establish the republic in 1916. After Yuan Shikai's death in 1916, China was politically fragmented. Its Beijing-based government was internationally recognized but virtually powerless; regional warlords controlled most of its territory. During this period , China participated in World War I and saw

12690-555: The failed Taiping Rebellion that ravaged southern China in the 1850s and 1860s and the Dungan Revolt (1862–1877) in the northwest. The initial success of the Self-Strengthening Movement of the 1860s was frustrated by a series of military defeats in the 1880s and 1890s. In the 19th century, the great Chinese diaspora began. Losses due to emigration were added to by conflicts and catastrophes such as

12825-409: The first authorized London Pharmacopoeia, was selected chiefly from the works of Mezue and Nicolaus de Salerno, but it was found to be so full of errors that the whole edition was cancelled, and a fresh edition was published in the following December. At this period the compounds employed in medicine were often heterogeneous mixtures, some of which contained from 20 to 70, or more, ingredients, while

12960-475: The first human inhabitants in the region arrived during the Paleolithic . By the late 2nd millennium BCE, the earliest dynastic states had emerged in the Yellow River basin. The 8th–3rd centuries BCE saw a breakdown in the authority of the Zhou dynasty , accompanied by the emergence of administrative and military techniques, literature , philosophy , and historiography . In 221 BCE, China

13095-456: The first time added to the official ones; the simple distilled waters were ordered of a uniform strength; sweetened spirits, cordials and ratafias were omitted as well as several compounds no longer used in London, although still in vogue elsewhere. A great improvement was effected in the edition published in 1746, in which only those preparations were retained which had received the approval of

13230-612: The growth of Buddhism during the Tang, and a flourishing of philosophy and the arts, as landscape art and porcelain were brought to new levels of complexity. However, the military weakness of the Song army was observed by the Jin dynasty . In 1127, Emperor Huizong of Song and the capital Bianjing were captured during the Jin–Song wars . The remnants of the Song retreated to southern China . The Mongol conquest of China began in 1205 with

13365-400: The informal paramount leader . The current general secretary is Xi Jinping , who took office on 15 November 2012. At the local level, the secretary of the CCP committee of a subdivision outranks the local government level; CCP committee secretary of a provincial division outranks the governor while the CCP committee secretary of a city outranks the mayor. The government in China is under

13500-409: The largest importer of Russian crude oil in 2022. China is the third-largest country in the world by land area after Russia , and the third- or fourth-largest country in the world by total area. China's total area is generally stated as being approximately 9,600,000 km (3,700,000 sq mi). Specific area figures range from 9,572,900 km (3,696,100 sq mi) according to

13635-582: The major initial work in the field is considered to be the Edwin Smith Papyrus in Egypt , Pliny 's pharmacopoeia. A number of early pharmacopoeia books were written by Persian and Arab physicians . These included The Canon of Medicine of Avicenna in 1025 AD, and works by Ibn Zuhr (Avenzoar) in the 12th century (and printed in 1491), and Ibn Baytar in the 14th century. The Shen-nung pen ts'ao ching (Divine Husbandman's Materia Medica)

13770-399: The majority of the pharmacopoeia committee; to these was added a list of those drugs only which were supposed to be the most efficacious. An attempt was made to simplify further the older formulae by the rejection of superfluous ingredients. In the edition published in 1788 the tendency to simplify was carried out to a much greater extent, and the extremely compound medicines which had formed

13905-414: The matter. This is notwithstanding the fact that, although the medical practitioner is naturally the best judge of the drug or preparations that will afford the best therapeutic result, they are not as competent as the pharmacist to say how that preparation can be produced in the most effective and satisfactory manner, nor how the purity of drugs can be tested. The change occurred with the fourth edition of

14040-508: The medical profession and to chemists and druggists that the General Medical Council brought out a new and amended edition in 1867. This dissatisfaction was probably owing partly to the fact that the majority of the compilers of the work were not engaged in the practice of pharmacy, and therefore not competent to decide upon the kind of preparations required for the method of their manufacture. The necessity for this element in

14175-660: The multiple consultation mechanisms that exist in Chinese government. According to the CCP constitution , its highest body is the National Congress held every five years. The National Congress elects the Central Committee , who then elects the party's Politburo , Politburo Standing Committee and the general secretary ( party leader ), the top leadership of the country. The general secretary holds ultimate power and authority over party and state and serves as

14310-720: The name of the Qin dynasty (221–206 BCE). Although use in Indian sources precedes this dynasty, this derivation is still given in various sources. The origin of the Sanskrit word is a matter of debate. Alternative suggestions include the names for Yelang and the Jing or Chu state. The official name of the modern state is the "People's Republic of China" ( simplified Chinese : 中华人民共和国 ; traditional Chinese : 中華人民共和國 ; pinyin : Zhōnghuá rénmín gònghéguó ). The shorter form

14445-787: The nationality of republics within that state differed from the de jure nature. The European Union has a supranational pharmacopoeia, the European Pharmacopoeia ; it has not replaced the national pharmacopoeias of EU member states but rather helps to harmonize them. Attempts have been made by international pharmaceutical and medical conferences to settle a basis on which a globally international pharmacopoeia could be prepared, but regulatory complexity and regional variation in conditions of pharmacy are hurdles to fully harmonizing across all countries (that is, defining thousands of details that can all be known to work successfully in all places). Nonetheless, some progress has been made under

14580-472: The other three great powers, China was one of the four major Allies of World War II , and was later considered one of the primary victors in the war. After the surrender of Japan in 1945, Taiwan, including the Penghu , was handed over to Chinese control ; however, the validity of this handover is controversial. China emerged victorious but war-ravaged and financially drained. The continued distrust between

14715-585: The patentee for infringement of patent rights. Hence the only solution is for the physician to use the chemical name (which cannot be patented) as given in the Pharmacopoeia, or, for those synthetic remedies not included in the Pharmacopoeia, the scientific and chemical name given in the British Pharmaceutical Codex . In most of the Neo-Latin names, Pharmacopoea is the more common spelling, although for several of them, Pharmacopoeia

14850-408: The physician prefers when writing a prescription to use the shorter name under which it is sold by the patentees . In this case the pharmacist is compelled to use the more expensive patented article, which may lead to complaints from the patient. If the physician were to use the same article under its pharmacopoeial name when the patented article is prescribed, they would become open to prosecution by

14985-553: The press , freedom of assembly , free formation of social organizations , freedom of religion and free access to the Internet . China has consistently been ranked amongst the lowest as an "authoritarian regime" by the Economist Intelligence Unit 's Democracy Index , ranking at 148th out of 167 countries in 2023. Other sources suggest that terming China as "authoritarian" does not sufficiently account for

15120-486: The principal remedies of physicians for 2,000 years were discarded, while a few powerful drugs which had been considered too dangerous to be included in the Pharmacopoeia of 1765 were restored to their previous position. In 1809 the French chemical nomenclature was adopted, and in 1815 a corrected impression of the same was issued. Subsequent editions were published in 1824, 1836, and 1851. The first Edinburgh Pharmacopoeia

15255-417: The protests and was replaced by Jiang Zemin . Jiang continued economic reforms, closing many SOEs and trimming down " iron rice bowl " (life-tenure positions). China's economy grew sevenfold during this time. British Hong Kong and Portuguese Macau returned to China in 1997 and 1999 , respectively, as special administrative regions under the principle of one country, two systems . The country joined

15390-477: The publication of such non-official formularies as Squire's Companion to the Pharmacopoeia and Martindale: The complete drug reference (formerly Martindale's: the extra pharmacopoeia ), in which all new remedies and their preparations, uses and doses are recorded, and in the former the varying strengths of the same preparations in the different pharmacopoeias are also compared (Squire's was incorporated into Martindale in 1952). The need of such works to supplement

15525-413: The purity of many unofficial drugs and preparations are given as well as the character of many glandular preparations and antitoxins that have come into use in medicine, but have not yet been introduced into the Pharmacopoeia. This work may also possibly serve as a standard under the Adulteration of Food and Drugs Act for the purity and strength of drugs not included in the Pharmacopoeia and as a standard for

15660-637: The sole control of the CCP. The CCP controls appointments in government bodies, with most senior government officials being CCP members. The National People's Congress (NPC), with nearly 3,000-members, is constitutionally the " highest organ of state power ", though it has been also described as a " rubber stamp " body. The NPC meets annually, while the NPC Standing Committee , around 150 members elected from NPC delegates, meets every couple of months. Elections are indirect and not pluralistic, with nominations at all levels being controlled by

15795-761: The south, the general Liu Yu secured the abdication of the Jin in favor of the Liu Song . The various successors of these states became known as the Northern and Southern dynasties , with the two areas finally reunited by the Sui in 581. The Sui restored the Han to power through China, reformed its agriculture, economy and imperial examination system, constructed the Grand Canal , and patronized Buddhism . However, they fell quickly when their conscription for public works and

15930-657: The standardization of Chinese characters, measurements , road widths, and currency . His dynasty also conquered the Yue tribes in Guangxi , Guangdong , and Northern Vietnam . The Qin dynasty lasted only fifteen years, falling soon after the First Emperor's death. Following widespread revolts during which the imperial library was burned , the Han dynasty emerged to rule China between 206 BCE and 220 CE, creating

16065-576: The time of the Warring States period of the 5th–3rd centuries BCE, there were seven major powerful states left. The Warring States period ended in 221 BCE after the state of Qin conquered the other six states, reunited China and established the dominant order of autocracy . King Zheng of Qin proclaimed himself the Emperor of the Qin dynasty , becoming the first emperor of a unified China. He enacted Qin's legalist reforms, notably

16200-675: The verb "to make" ( Ancient Greek : ποιεῖν , romanized :  poiein ), and the abstract noun suffix -ία -ia . In early modern editions of Latin texts, the Greek diphthong οι ( oi ) is latinized to its Latin equivalent oe which is in turn written with the ligature œ , giving the spelling pharmacopœia ; in modern UK English , œ is written as oe , giving the spelling pharmacopoeia , while in American English oe becomes e , giving us pharmacopeia . Although older writings exist which deal with herbal medicine ,

16335-503: The works of Galenus . Apparently he burnt them. According to recent research communicated at the congresses of the International Society for the History of Medicine by the scholar Francisco Javier González Echeverría, Michel De Villeneuve ( Michael Servetus ) also published a pharmacopoeia. De Villeneuve, fellow student of Vesalius and the best galenist of Paris according to Johann Winter von Andernach , published

16470-485: The world), 1,221 species of birds (eighth), 424 species of reptiles (seventh) and 333 species of amphibians (seventh). Wildlife in China shares habitat with, and bears acute pressure from, one of the world's largest population of humans. At least 840 animal species are threatened, vulnerable or in danger of local extinction , due mainly to human activity such as habitat destruction, pollution and poaching for food, fur and traditional Chinese medicine . Endangered wildlife

16605-428: The world), 13.2% from hydroelectric power (largest), 9.4% from wind (largest), 6.2% from solar energy (largest), 4.6% from nuclear energy (second-largest), 3.3% from natural gas (fifth-largest), and 2.2% from bioenergy (largest); in total, 31% of China's energy came from renewable energy sources. Despite its emphasis on renewables, China remains deeply connected to global oil markets and next to India, has been

16740-709: Was wiped out by the KMT armies in 1934, leading the CCP to initiate the Long March and relocate to Yan'an in Shaanxi . It would be the base of the communists before major combat in the Chinese Civil War ended in 1949. In 1931, Japan invaded and occupied Manchuria . Japan invaded other parts of China in 1937, precipitating the Second Sino-Japanese War (1937–1945), a theater of World War II . The war forced an uneasy alliance between

16875-406: Was captured by a coalition of peasant rebel forces led by Li Zicheng . The Chongzhen Emperor committed suicide when the city fell. The Manchu Qing dynasty , then allied with Ming dynasty general Wu Sangui , overthrew Li's short-lived Shun dynasty and subsequently seized control of Beijing, which became the new capital of the Qing dynasty. The Qing dynasty, which lasted from 1644 until 1912,

17010-608: Was compiled in 659 AD by a team of 23 pharmaceutical scientists led by Su jing during the Tang dynasty (618-907 AD) and was called the Xinxiu bencao (Newly Revised Canon of Material Medical). The work consists of 20 volumes with one dedicated to the table of contents, and 25 volumes of pictures with one volume dedicated to the table of contents. A third part consisting of seven volumes contained illustrated descriptions. The text contains descriptions of 850 medicines with 114 new ones. The work

17145-523: Was devastated and weakened by the An Lushan rebellion in the 8th century. In 907, the Tang disintegrated completely when the local military governors became ungovernable. The Song dynasty ended the separatist situation in 960, leading to a balance of power between the Song and the Liao dynasty . The Song was the first government in world history to issue paper money and the first Chinese polity to establish

17280-522: Was ended upon the Northern Expedition conducted by the Kuomintang (KMT) to reunify the country. The Chinese Civil War began in 1927, when KMT forces purged members of the rival Chinese Communist Party (CCP), who proceeded to engage in sporadic fighting against the KMT-led Nationalist government . Following the country's invasion by the Empire of Japan in 1937, the CCP and KMT formed

17415-419: Was published in 1699 and the last in 1841; the first Dublin Pharmacopoeia in 1807 and the last in 1850. The preparations contained in these three pharmacopoeias were not all uniform in strength, a source of much inconvenience and danger to the public, when powerful preparations such as dilute hydrocyanic acid were ordered in the one country and dispensed according to the national pharmacopoeia in another. As

17550-408: Was rebuked, with millions rehabilitated. Deng Xiaoping took power in 1978, and instituted large-scale political and economic reforms , together with the " Eight Elders ", most senior and influential members of the party. The government loosened its control and the communes were gradually disbanded. Agricultural collectivization was dismantled and farmlands privatized. While foreign trade became

17685-602: Was split, with both sides claiming to be the sole legitimate government of China . Following the implementation of land reforms , further attempts by the PRC to realize communism failed: the Great Leap Forward was largely responsible for the Great Chinese Famine that ended with millions of Chinese people having died, and the subsequent Cultural Revolution was a period of social turmoil and persecution characterized by Maoist populism. Following

17820-601: Was strengthened in part to suppress anti-Qing sentiment with the policy of valuing agriculture and restraining commerce, like the Haijin during the early Qing period and ideological control as represented by the literary inquisition , causing some social and technological stagnation. In the mid-19th century, the Opium Wars with Britain and France forced China to pay compensation, open treaty ports, allow extraterritoriality for foreign nationals, and cede Hong Kong to

17955-548: Was the last imperial dynasty of China. The Ming-Qing transition (1618–1683) cost 25 million lives, but the Qing appeared to have restored China's imperial power and inaugurated another flowering of the arts. After the Southern Ming ended, the further conquest of the Dzungar Khanate added Mongolia, Tibet and Xinjiang to the empire. Meanwhile, China's population growth resumed and shortly began to accelerate. It

18090-476: Was unified under an emperor , ushering in more than two millennia of imperial dynasties including the Qin , Han , Tang , Yuan , Ming , and Qing . With the invention of gunpowder and paper , the establishment of the Silk Road , and the building of the Great Wall , Chinese culture flourished and has heavily influenced both its neighbors and lands further afield. However, China began to cede parts of

18225-432: Was used throughout China for the next 400 years. A dated work appeared in Nuremberg in 1542; a passing student Valerius Cordus showed a collection of medical prescriptions, which he had selected from the writings of the most eminent medical authorities, to the physicians of the town, who urged him to print it for the benefit of the apothecaries , and obtained the sanction of the senatus for his work. A work known as

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