Serono was a biotechnology company headquartered in Geneva , Switzerland . It was acquired by the German pharmaceutical company Merck in 2006. The company was founded as the Serono Pharmacological Institute by Cesare Serono in 1906 in Rome , Italy . A key step in its development was the discovery of a method of extracting urinary gonadotropins by Dr. Piero Donini. Serono was incorporated in 1987 and the holding company, Ares-Serono S.A., changed its name to Serono S.A. in May 2000.
32-476: Manteia Predictive Medicine S.A. (initially incorporated under the name "GenInEx S.A.") was a start-up company created in November 2000 as a spin-off of Serono , a Swiss-based biotechnology company, now part of Merck-Serono, by private founders. Its aim was to provide preventive and curative treatment guidelines for common and complex diseases. These guidelines were envisaged as composed of two parts: The company
64-594: A full-time job, in 1867, the U.S. House Committee on the Judiciary , led by Congressman William Lawrence , conducted an inquiry into the creation of a "law department" headed by the attorney general and also composed of the various department solicitors and United States attorneys . On February 19, 1868, Lawrence introduced a bill in Congress to create the Department of Justice. President Ulysses S. Grant signed
96-614: A small operation, with a staff of six. The main function was to generate legal opinions at the request of Lincoln and cabinet members, and handle occasional cases before the Supreme Court. Lincoln's cabinet was full of experienced lawyers who seldom felt the need to ask for his opinions. Bates had no authority over the US Attorneys around the country. The federal court system was handled by the Interior Department;
128-464: A website that supported the USA PATRIOT Act . It was criticized by government watchdog groups for its alleged violation of U.S. Code Title 18 Section 1913, which forbids money appropriated by Congress to be used to lobby in favor of any law, actual or proposed. The website has since been taken offline. On October 5, 2021, U.S. Deputy Attorney General Lisa Monaco has announced the formation of
160-548: Is called Merck Serono . Its headquarters was in Geneva, within the new Serono facilities. The US operations remain near Boston and was renamed here EMD Serono due to trademark issues with Merck & Co./MSD . The process of merging started in January 2007 after various business regulatory reviews and phases were complete. Until that time, Serono and Merck KGaA operated as separate entities. The new, combined entity, Merck Serono
192-533: Is the size of other large biotechs. In 2011, a decision was made to close the Geneva headquarters and move the headquarters to Darmstadt, Germany resulting in job losses to most of the employees in Geneva. Serono operated in 44 countries, with manufacturing facilities in eight countries and sales in over 90 countries. Main manufacturing sites were in Switzerland, Italy, Spain and France; a fifth facility in Israel
224-603: The Justice Department , is a federal executive department of the United States government tasked with the enforcement of federal law and administration of justice in the United States. It is equivalent to the justice or interior ministries of other countries. The department is headed by the U.S. attorney general , who reports directly to the president of the United States and is a member of
256-574: The federal government took on some law enforcement responsibilities, and the Department of Justice was tasked with performing these. In 1884, control of federal prisons was transferred to the new department, from the Department of the Interior . New facilities were built, including the penitentiary at Leavenworth in 1895, and a facility for women located in West Virginia , at Alderson
288-657: The Attorney General's office in the Department of Justice Main Building in Washington, D.C. The building was renamed in honor of former Attorney General Robert F. Kennedy in 2001. It is sometimes referred to as "Main Justice". The Justice Department also had a War Division during World War II . It was created in 1942 and disestablished in 1945. Several federal law enforcement agencies are administered by
320-472: The Constitution. Both Akerman and Bristow used the Department of Justice to vigorously prosecute Ku Klux Klan members in the early 1870s. In the first few years of Grant's first term in office, there were 1000 indictments against Klan members, with over 550 convictions from the Department of Justice. By 1871, there were 3000 indictments and 600 convictions, with most only serving brief sentences, while
352-498: The Department of Justice) "who prosecutes on behalf of justice (or the Lady Justice)". The motto's conception of the prosecutor (or government attorney) as being the servant of justice itself finds concrete expression in a similarly-ordered English-language inscription ("THE UNITED STATES WINS ITS POINT WHENEVER JUSTICE IS DONE ITS CITIZENS IN THE COURTS") in the above-door paneling in the ceremonial rotunda anteroom just outside
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#1732790186393384-536: The Department of Justice. Similarly the Office of Domestic Preparedness left the Justice Department for the Department of Homeland Security, but only for executive purposes. The Office of Domestic Preparedness is still centralized within the Department of Justice, since its personnel are still officially employed within the Department of Justice. In 2003, the Department of Justice created LifeAndLiberty.gov,
416-613: The Department of Justice: In March 2003, the United States Immigration and Naturalization Service was abolished and its functions transferred to the United States Department of Homeland Security . The Executive Office for Immigration Review and the Board of Immigration Appeals , which review decisions made by government officials under Immigration and Nationality law, remain under jurisdiction of
448-547: The Department of the Interior, the prosecution of all federal crimes, and the representation of the United States in all court actions, barring the use of private attorneys by the federal government. The law also created the office of Solicitor General to supervise and conduct government litigation in the Supreme Court of the United States . With the passage of the Interstate Commerce Act in 1887,
480-410: The Geneva research site moved to a brand new campus (Horizon Secheron) in the heart of Geneva in 2006. This facility and the headquarters were closed by Merck KGaA in 2013. The building was sold back to Bertarelli family. In 2005, Serono agreed to a $ 704 million settlement with the Department of Justice to resolve civil and criminal allegations that the company engaged in a fraudulent scheme to promote
512-468: The Treasury handled claims. Most of the opinions turned out by Bates's office were of minor importance. Lincoln gave him no special assignments and did not seek his advice on Supreme Court appointments. Bates did have an opportunity to comment on general policy as a cabinet member with a strong political base, but he seldom spoke up. Following unsuccessful efforts in 1830 and 1846 to make attorney general
544-553: The U.S. federal government in litigation: the Criminal , Civil , Antitrust , Tax , Civil Rights , Environment and Natural Resources , National Security , and Justice Management Divisions . The department also includes the U.S. Attorneys' Offices for each of the 94 U.S. federal judicial districts . The U.S. Congress created the Justice Department in 1870 during the presidency of Ulysses S. Grant . The Justice Department's functions originally date to 1789, when Congress created
576-575: The acquisition in 1997 of GBRI from GlaxoWelcome, becoming its Geneva based research institute named SPRI, and the Manteia Predictive Medicine spin-off, Serono also nursed the emergence of now a commercial leading massive parallel sequencing technology. 36% of Serono was sold to Merck KGaA in Sept. 2006 for €10.6 billion; Merck KGaA paid CHF 1,100 for each share. The new entity, which merges Serono with Merck's Ethicals division,
608-443: The bill into law on June 22, 1870. Grant appointed Amos T. Akerman as attorney general and Benjamin H. Bristow as America's first solicitor general the same week that Congress created the Department of Justice. The Department's immediate function was to preserve civil rights. It set about fighting against domestic terrorist groups who had been using both violence and litigation to oppose the 13th , 14th , and 15th Amendments to
640-522: The drug Serostim for off-label uses and paid out illegal kickbacks for prescribing the drug in violation of the False Claims Act . The settlement is, to date, the ninth largest pharmaceutical settlement in U.S. history. Serono provides Fertility LifeLines as a free and confidential source of information to infertility patients. United States Department of Justice The United States Department of Justice ( DOJ ), also known as
672-647: The fields of reproductive health , multiple sclerosis , growth & metabolism and dermatology . The eight biotechnology products are available in four core therapeutic areas: neurology for the treatment of relapsing forms of multiple sclerosis , reproductive health for treatments of infertility , dermatology , where Serono has launched biologics in Europe for moderate-to-severe psoriasis , and growth and metabolism for treatments for HIV-associated wasting and growth deficiencies. The company also conducts research in oncology and autoimmune diseases . Through
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#1732790186393704-470: The office of the Attorney General. The office of the attorney general was established by the Judiciary Act of 1789 as a part-time job for one person, but grew with the bureaucracy . At one time, the attorney general gave legal advice to the U.S. Congress , as well as the president ; however, in 1819, the attorney general began advising Congress alone to ensure a manageable workload. Until 1853,
736-536: The original intended meaning of the Latin motto appearing on the Department of Justice seal, Qui Pro Domina Justitia Sequitur (literally "Who For Lady Justice Strives"). It is not even known exactly when the original version of the DOJ seal itself was adopted, or when the motto first appeared on the seal. The most authoritative opinion of the DOJ suggests that the motto refers to the Attorney General (and thus, by extension, to
768-687: The president's Cabinet . The current attorney general is Merrick Garland , who has served since March 2021. The Justice Department contains most of the United States' federal law enforcement agencies , including the Federal Bureau of Investigation , the U.S. Marshals Service , the Bureau of Alcohol, Tobacco, Firearms and Explosives , the Drug Enforcement Administration , and the Federal Bureau of Prisons . The department also has eight divisions of lawyers who represent
800-629: The ringleaders were imprisoned for up to five years in the federal penitentiary in Albany, New York . The result was a dramatic decrease in violence in the South. Akerman gave credit to Grant and told a friend that no one was "better" or "stronger" than Grant when it came to prosecuting terrorists. George H. Williams , who succeeded Akerman in December 1871, continued to prosecute the Klan throughout 1872 until
832-412: The salary of the attorney general was set by statute at less than the amount paid to other Cabinet members. Early attorneys general supplemented their salaries by running private law practices, often arguing cases before the courts as attorneys for paying litigants. The lightness of the office is exemplified by Edward Bates (1793–1869), Attorney General under Abraham Lincoln (1861 to 1864). Bates had only
864-436: The spring of 1873, during Grant's second term in office. Williams then placed a moratorium on Klan prosecutions partially because the Justice Department, inundated by cases involving the Klan, did not have the manpower to continue prosecutions. The "Act to Establish the Department of Justice" drastically increased the attorney general's responsibilities to include the supervision of all United States attorneys, formerly under
896-430: Was basing its strategy on the development of so-called "DNA colony sequencing" technology (now commercialized by Illumina ), its proprietary massive parallel sequencing technology whose development had been initiated in late 1996 at Glaxo-Welcome's Geneva Biomedical Research Institute (GBRI), by Pascal Mayer and Laurent Farinelli. This work has been protected by several patents and patents applications, publications and
928-461: Was closed in 2004 owing to its obsolescence. Research and development facilities were maintained in Geneva, Switzerland , Boston, USA , and Ivrea , Italy. It employed over 4,750 people with worldwide revenues of USD 2,586.4 million (2005). It had eight biotechnology products on the market, and more than 25 ongoing preclinical and clinical development projects at the end of 2005. Serono Headquarters and
960-425: Was completed in 1935 from a design by Milton Bennett Medary . Upon Medary's death in 1929, the other partners of his Philadelphia firm Zantzinger, Borie and Medary took over the project. On a lot bordered by Constitution and Pennsylvania Avenues and Ninth and Tenth Streets, Northwest, it holds over 1,000,000 square feet (93,000 m ) of space. Various efforts, none entirely successful, have been made to determine
992-506: Was discussed in presentations at international conferences from 1998 to 2001. By the end of 2003, while the company was progressing along its plans towards realizing an industrial instrument capable of sequencing a complete human genome in approximately 24 hours, strategic considerations led the main shareholder ( Serono ) to sell Manteia's colony DNA sequencing technology to UK based Solexa Ltd, now part of Illumina (company) . Serono Serono develops and markets pharmaceuticals in
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1024-615: Was established in 1924. In 1933, President Franklin D. Roosevelt issued an executive order which gave the Department of Justice responsibility for the "functions of prosecuting in the courts of the United States claims and demands by, and offsenses [ sic ] against, the Government of the United States, and of defending claims and demands against the Government, and of supervising the work of United States attorneys, marshals, and clerks in connection therewith, now exercised by any agency or officer..." The U.S. Department of Justice building
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