Congenital syphilis is syphilis that occurs when a mother with untreated syphilis passes the infection to her baby during pregnancy or at birth . It may present in the fetus , infant , or later. Clinical features vary and differ between early onset, that is presentation before 2-years of age, and late onset, presentation after age 2-years. Infection in the unborn baby may present as poor growth , non-immune hydrops leading to premature birth or loss of the baby , or no signs . Affected newborns mostly initially have no clinical signs. They may be small and irritable. Characteristic features include a rash, fever , large liver and spleen , a runny and congested nose , and inflammation around bone or cartilage . There may be jaundice , large glands , pneumonia ( pneumonia alba ), meningitis , warty bumps on genitals , deafness or blindness. Untreated babies that survive the early phase may develop skeletal deformities including deformity of the nose , lower legs , forehead , collar bone , jaw , and cheek bone . There may be a perforated or high arched palate , and recurrent joint disease . Other late signs include linear perioral tears , intellectual disability , hydrocephalus , and juvenile general paresis. Seizures and cranial nerve palsies may first occur in both early and late phases. Eighth nerve palsy , interstitial keratitis and small notched teeth may appear individually or together; known as Hutchinson's triad .
97-420: Joaquín Sorolla y Bastida ( Valencian : Joaquim Sorolla i Bastida , 27 February 1863 – 10 August 1923) was a Spanish painter . Sorolla excelled in the painting of portraits , landscapes , and monumental works of social and historical themes. His most typical works are characterized by a dexterous representation of the people and landscape under the bright sunlight of Spain and sunlit water. Joaquín Sorolla
194-467: A Jarisch-Herxheimer reaction , which is a temporary reaction that usually occurs within a few hours of starting penicillin and resolves by 24 hours. The reaction is characterized by cramping, fever, muscle aches and a rash. Treatment is supportive and fetal heart rate monitoring is recommended. Syphilis affects around one million pregnancies a year. In 2016, there were around 473 cases of congenital syphilis per 100,000 live births and 204,000 deaths from
291-484: A case-by-case basis. Treatment cannot reverse any deformities, brain, or permanent tissue damage that has already occurred. A Cochrane review found that antibiotics may be effective for serological cure but in general the evidence around the effectiveness of antibiotics for congenital syphilis is uncertain due to the poor methodological quality of the small number of trials that have been conducted. Up to 40% of pregnant women treated for congenital syphilis will develop
388-515: A compromise between the essence and style of Pompeu Fabra 's guidelines, but also allowing the use of Valencian idiosyncrasies. Until its dissolution in November 2013, the public-service Ràdio Televisió Valenciana (RTVV) was the main broadcaster of radio and television in Valencian language. The Generalitat Valenciana constituted it in 1984 in order to guarantee the freedom of information of
485-593: A contract to paint a series of oils on life in Spain. These 14 magnificent murals, installed to this day in the Hispanic Society of America building in Manhattan, range from 12 to 14 feet in height, and total 227 feet in length. The major commission of his career, it dominated the later years of Sorolla's life. Huntington had envisioned the work depicting a history of Spain, but the painter preferred
582-526: A diverse nature (political, social, economic). In the previous centuries the Catalan spoken in the territory of the Kingdom of Valencia was called in different ways: romanç (13th century) and catalanesch (during the 14th century, for the medieval concept of nation as a linguistic community). The concept of the Valencian language appeared with a particularistic character due to the reinforced nature of
679-562: A formal adoption of the so-called Normes de Castelló (Castelló Norms), a set of guidelines following Pompeu Fabra's Catalan language norms. The letters k , y and w only appear in loanwords. In the case of y it also appears in the digraph ny . Most of the letters are pronounced the same in both standards (Valencian and Catalan). The letters c and g have a soft and hard pronunciation similar to English and other Romance languages, ç (found also in Portuguese and French) always has
776-503: A language different from Catalan, while 41% considered the languages to be the same. By applying a binary logistic regression to the same data, it was also found that different opinions about the unity of the language are different between people with certain levels of studies and the opinion also differs between each of the Valencian provinces. The opinion agreeing on the unity of Valencian and Catalan has significant differences regarding age, level of education and province of residence, with
873-555: A language, that is, a "linguistic system" [...] From this group of varieties, Valencian has the same hierarchy and dignity as any other dialectal modality of that linguistic system [...] The AVL was established in 1998 by the PP - UV government of Eduardo Zaplana . According to El País , Jordi Pujol , then president of Catalonia and of the CiU , negotiated with Zaplana in 1996 to ensure the linguistic unity of Catalan in exchange for CiU support of
970-405: A majority of those aged 18–24 (51%) and those with a higher education (58%) considering Valencian to be the same language as Catalan. This can be compared to those aged 65 and above (29%) and those with only primary education (32%), where the same view has its lowest support. People living in the province of Castellón are more prone to be in favor of the unity of the language, while people living in
1067-693: A primary syphilitic chancre but may present with signs of secondary syphilis (i.e. generalized body rash). Often these babies will develop syphilitic rhinitis ("snuffles"), the mucus from which is laden with the T. pallidum bacterium, and therefore highly infectious. If a baby with congenital syphilis is not treated early, damage to the bones, teeth, eyes, ears, and brain can occur. Neurosyphilis in newborns may present as cranial nerve palsies , cerebral infarcts (strokes), seizures or eye abnormalities. Many newborns with congenital syphilis, 55% by some estimates, do not exhibit any symptoms initially, with signs and symptoms developing days to months later. This
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#17327763493101164-593: A rise of more than 900 percent in Mississippi over the preceding five years. Congenital syphilis was first described in Europe during the fifteenth century by the Spanish physician Gaspar Torrella [ es ] . Nineteenth century physicians held the belief that congenital syphilis was contracted from contaminated semen at time of conception. Serological tests for syphilis were introduced in 1906, and it
1261-474: A soft pronunciation and may appear in word final position. The only differences between the main standards are the contrast of b /b/ and v /v/ (also found in Insular Catalan), the treatment of long consonants with a tendency to simplification in Valencian (see table with main digraphs and letter combinations), the affrication ( /d͡ʒ/ ) of both soft g (after front vowels) and j (in most cases),
1358-650: A sun-dappled landscape for María at La Granja (1907), but so did Spanish royalty, for the Portrait of King Alfonso XIII in a Hussar's Uniform (1907). For Portrait of Mr. Louis Comfort Tiffany (1911), the American artist posed seated at his easel in his Long Island garden, surrounded by extravagant flowers. The conceit reaches its high point in My Wife and Daughters in the Garden (1910, see gallery below), in which
1455-580: A survey sampling more than 6,600 people in the provinces of Castellón, Valencia, and Alicante. The survey simply collected the answers of respondents and did not include any testing or verification. The results were: The survey shows that, although Valencian is still the common language in many areas in the Valencian Community, where slightly more than half of the Valencian population are able to speak it, most Valencians do not usually use Valencian in their social relations. Moreover, according to
1552-405: A treponemal test followed by a non-treponemal test in the reverse diagnostic sequence). Positivity of both tests indicates active syphilis or previous infection that was treated. Quantitative non-treponemal tests are monitored for disease activity and response to treatment, with RPR is expected to decrease by a factor of four compared to pre-treatment levels after successful treatment of syphilis in
1649-606: Is tomata outside of Southern Valencian) and matalaf 'mattress' (which is matalap in parts of Valencia, including the Southern Valencian area). Below are a selection of words which differ or have different forms in Standard Valencian and Catalan. In many cases, both standards include this variation in their respective dictionaries, but differ as to what form is considered primary. In other cases, Valencian includes colloquial forms not present in
1746-529: Is penicillin allergy , antimicrobial desensitisation is an option. Syphilis affects around one million pregnancies a year. In 2016, there were around 473 cases of congenital syphilis per 100,000 live births and 204,000 deaths from the disease worldwide. Of the 660,000 congenital syphilis cases reported in 2016, 143,000 resulted in deaths of unborn babies, 61,000 deaths of newborn babies, 41,000 low birth weights or preterm births, and 109,000 young children diagnosed with congenital syphilis. Around 75% were from
1843-424: Is a subset of cases of congenital syphilis. Newborns may be asymptomatic and are only identified on routine prenatal screening . If not identified and treated, these newborns develop poor feeding and runny nose . By definition, early congenital syphilis occurs in children between 0 and 2 years old. Congenital syphilis that is diagnosed after 2 years of age, either because it was not diagnosed earlier or because it
1940-754: Is also variation within Valencia, such as 'corn', which is dacsa in Central and Southern Valencian, but panís in Alicante and Northern Valencian (as well as in North-Western Catalan). Since Standard Valencian is based on the Southern dialect, words from this dialect are often used as primary forms in the standard language, despite other words traditionally being used in other Valencian dialects. Examples of this are tomaca 'tomato' (which
2037-520: Is by safe sex to prevent syphilis in the mother, and early screening and treatment of syphilis in pregnancy. One intramuscular injection of benzathine penicillin G administered to a pregnant woman early in the illness can prevent congenital syphilis in her baby. Treatment of suspected congenital syphilis is with penicillin by injection; benzylpenicillin into vein , or procaine benzylpenicillin into muscle . During times of penicillin unavailability, ceftriaxone may be an alternative. Where there
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#17327763493102134-452: Is caused by the bacterium Treponema pallidum subspecies pallidum when it infects the baby after crossing the placenta or from contact with a syphilitic sore at birth. It is not transmitted during breastfeeding unless there is an open sore on the mother's breast . The unborn baby can become infected at any time during the pregnancy. Most cases occur due to inadequate antenatal screening and treatment during pregnancy. The baby
2231-413: Is found in a judicial process of Minorca against Gil de Lozano, dated between 1343 and 1346, in which it is said that the mother of the indicted, Sibila, speaks valencianesch because she was from Orihuela (formerly Oriola). The concept of Valencian language appeared in the second half of the 14th century and it was progressively consolidated at the same time that its meaning changed due to events of
2328-463: Is highly infectious if the rash and snuffles are present. The disease may be suspected from tests on the mother; blood tests and ultrasound . Tests on the baby may include blood tests, CSF analysis and medical imaging . Findings may reveal anemia and low platelets . Other findings may include low sugars , proteinuria and hypopituitarism . The placenta may appear large and pale. Other investigations include testing for HIV . Prevention
2425-593: Is more commonly carried out on the mother and the infant to diagnose maternal and congenital syphilis. In the mother, a serologic diagnosis of syphilis is made using a nontreponemal test for syphilis such as the Venereal Disease Research Laboratory test ( VDRL ) or Rapid plasma reagin (RPR) followed by a treponemal test, such as the Treponema pallidum particle agglutination assay (TP-PA) (the sequence of testing may be reversed with
2522-409: Is often exhibited together with that of his contemporaries and friends, John Singer Sargent and Anders Zorn . Although formal portraiture was not Sorolla's genre of preference, because it tended to restrict his creative appetites and could reflect his lack of interest in his subjects, the acceptance of portrait commissions proved profitable, and the portrayal of his family was irresistible. Sometimes
2619-750: Is regulated by the Acadèmia Valenciana de la Llengua (AVL), following the legacy established by the Castelló Norms , which adapt Catalan orthography to Valencian idiosyncrasies. Some of the most important works of Valencian literature experienced a Golden Age during the Late Middle Ages and the Renaissance . Important works include Joanot Martorell 's chivalric romance Tirant lo Blanch , and Ausiàs March 's poetry. The first book produced with movable type in
2716-569: Is responsible for 50-70% of infections, with syphilis being present for more than 1 year thought to be responsible for about 15% of transmission. It is not transmitted during breastfeeding unless there is an open sore on the mother's breast . Direct observation of Treponema pallidum from one of the lesions in the mother or infant is diagnostic and can be carried out using dark field microscopy , direct fluorescent antibody testing or immunohistochemical staining , however these tests are not readily available in many settings. Serological testing
2813-457: Is the triumph of naturalism, as it recreates the indoor environment of the laboratory, catching the luminous atmosphere produced by the artificial reddish-yellow light of a gas burner that contrasts with the weak mauvish afternoon light that shines through the window. These paintings may be among the most outstanding world paintings of this genre. An even greater turning point in Sorolla's career
2910-592: Is traditionally spoken along the coast and in some inland areas in the provinces of Alicante and Castellón, from Vinaròs (northernmost point of the extension of Valencian on the coast of the Valencian Community) to Guardamar (southernmost point of Valencian). In 2010 the Generalitat Valenciana , or Valencian government, published a study, Coneixement i ús social del valencià (Knowledge and Social Use of Valencian), which included
3007-469: Is treated with once weekly penicillin injections for three weeks. The mother's partner should also be evaluated and treated. The fetus is at greatest risk of contracting syphilis when the mother is in the early stages of infection, but the disease can be passed at any point during pregnancy, even during delivery. An affected child can be treated using antibiotics much like an adult; however, any developmental symptoms are likely to be permanent. The greater
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3104-475: Is usually due to bleeding into the lungs . Syphilis may be transmitted from mother to the fetus during any stage of pregnancy. It is most commonly transmitted via cross placental transfer of Treponema pallidum bacteria from mother to the fetus during pregnancy with transmission via exposure to genital lesions during childbirth being less common. The highest rate of transmission occurs in mothers with early syphilis (infection present for less than 1 year), which
3201-848: The Normes del Puig (Norms of El Puig), drawn up by the Royal Academy of Valencian Culture ( Real Acadèmia de Cultura Valenciana , RACV), an institution founded in 1915 by the Deputation of Valencia, but its use is very marginal. The official status of Valencian is regulated by the Spanish Constitution and the Valencian Statute of Autonomy , together with the Law on the Use and Teaching of Valencian (ca) . Article 6 of
3298-521: The Iberian Peninsula was printed in the Valencian variety. The earliest recorded chess game with modern rules for moves of the queen and bishop was in the Valencian poem Scachs d'amor (1475). The Valencian language is usually assumed to have spread in the Kingdom of Valencia when Catalan and Aragonese colonists settled the territory after the conquests carried out by James I
3395-563: The J. Paul Getty Museum . In 1960, Sorolla, el pintor de la luz , a short documentary written and directed by Manuel Domínguez was presented at the Cannes Film Festival . The Spanish National Dance Company honored the painter's The Provinces of Spain by producing a ballet Sorolla based on the paintings. The high-speed railway station in Valencia is named after Sorolla . In 2007 many of his works were exhibited at
3492-741: The National Gallery , London , held a major temporary Sorolla exhibition, titled Sorolla: Spanish Master of Light . In 2022 the Palazzo Reale in Milan held a major temporary Sorolla exhibition, titled Joaquin Sorolla: Pittore di luce (painter of light). Valencian language Valencian ( valencià ) or the Valencian language ( llengua valenciana ) is the official, historical and traditional name used in
3589-1119: The Petit Palais in Paris , alongside those of John Singer Sargent , a contemporary who painted in a similarly impressionist-influenced manner. In 2009, there was a special exhibition of his works at the Prado in Madrid , and in 2010, the exhibition visited the Oscar Niemeyer Museum in Curitiba , Brazil . From 5 December 2011 to 10 March 2012, several of Sorolla's works were exhibited in Queen Sofía Spanish Institute , in New York. This exhibition included pieces used during Sorolla's eight-year research for Vision of Spain . An exhibition titled Sorolla & America explored Sorolla's unique relationship with
3686-585: The Provinces of Spain at the Hispanic Society of America , opened to the public in 1926. The room closed for remodeling in 2008, and the murals toured museums in Spain for the first time. The Sorolla Room reopened in 2010, with the murals on permanent display. Sorolla's influence on some other Spanish painters, such as Alberto Pla y Rubio and Julio Romero de Torres , was so noted that they are described as "sorollista." After his death, Sorolla's widow, Clotilde García del Castillo, left many of his paintings to
3783-645: The Royal Academy of Valencian Culture ( Real Acadèmia de Cultura Valenciana , RACV), which considers itself a rival language academy to the AVL, and promotes an alternative orthography , treating Valencian as an independent language, as opposed to a variety of Catalan. Compared to Standard Valencian, this orthography excludes many words not traditionally used in the Valencian Community, and also prefers spellings such as ⟨ch⟩ for /tʃ/ and ⟨y⟩ for /j/ (as in Spanish ). Besides, these alternative Norms are also promoted and taught by
3880-566: The Valencian Community of Spain to refer to the Romance language also known as Catalan , either as a whole or in its Valencia-specific linguistic forms. The Valencian Community's 1982 Statute of Autonomy officially recognises Valencian as the name of the regional language. Valencian displays transitional features between Ibero-Romance languages and Gallo-Romance languages . According to philological studies,
3977-690: The 15th century, the so-called Valencian Golden Age, the name "Valencian" was already the usual name of the predominant language of the Kingdom of Valencia , and the names of vulgar , romanç or catalanesch had fallen into disuse. Joanot Martorell , author of the novel Tirant lo Blanch , said: " lit. ' Me atrevire expondre: no solament de lengua anglesa en portuguesa. Mas encara de portuguesa en vulgar valenciana: per ço que la nacio d·on yo so natural se·n puxa alegrar ' ." ("I dare to express myself: not only in English in Portuguese. But even so from Portuguese to vulgar Valencian: for that
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4074-791: The Chicago International Exhibition, where it was acquired and subsequently donated to the Washington University in St. Louis Museum in St. Louis, Missouri . He soon rose to general fame and became the acknowledged head of the modern Spanish school of painting. His picture The Return from Fishing (1894) was much admired at the Paris Salon and was acquired by the state for the Musée du Luxembourg . It indicated
4171-576: The Conqueror . A new resettlement in the 17th century, after the expulsion of the Moriscos , largely led by Castilians, defined the Spanish language varieties of inland Valencia. However, Valencian has historically been the predominant and administrative language in the kingdom. The first documental reference to the usage of the term valencià to refer to the spoken language of the Valencians
4268-725: The Hispanic Society of America, was capped by the Portrait of Mr. Taft, President of the United States , This portrait, which was painted at the White House, is on permanent display at the Taft Museum of Art in Cincinnati, Ohio. The appearance of sunlight could be counted on to rouse his interest, and it was outdoors where he found his ideal portrait settings. Thus, not only did his daughter pose standing in
4365-535: The IEC standard. Primary forms in each standard are shown in bold (and may be more than one form). Words in brackets are present in the standard in question, but differ in meaning from how the cognate is used in the other standard. Valencian and Catalan use the Latin script , with some added symbols and digraphs. The Catalan-Valencian orthographies are systematic and largely phonologically based. Standardisation of Catalan
4462-929: The Legion of Honour. The show included nearly 500 works, early paintings as well as recent sun-drenched beach scenes, landscapes, and portraits, a productivity which amazed critics and was a financial triumph. Though subsequent large-scale exhibitions in Germany and London were greeted with more restraint, while in England in 1908 Sorolla met Archer Milton Huntington , who made him a member of The Hispanic Society of America in New York City , and invited him to exhibit there in 1909. The exhibition comprised 356 paintings, 195 of which sold. Sorolla spent five months in America and painted more than twenty portraits. Sorolla's work
4559-624: The PP, RTVV announced in 2012 a plan to shed 70% of its labour. The plan was nullified on 5 November 2013 by the National Court after trade unions appealed against it. On that same day, the President de la Generalitat Alberto Fabra (also from PP ) announced RTVV would be closed, claiming that reinstating the employees was untenable. On 27 November, the legislative assembly passed the dissolution of RTVV and employees organised to take control of
4656-806: The Paris Universal Exposition of 1900 won him a medal of honour and his nomination as Knight of the Legion of Honour ; within the next few years Sorolla was honoured as a member of the Fine Art Academies of Paris, Lisbon , and Valencia, and as a Favourite Son of Valencia. A special exhibition of his works—figure subjects, landscapes, and portraits—at the Galeries Georges Petit in Paris in 1906 eclipsed all his earlier successes and led to his appointment as Officer of
4753-544: The Spanish public. The paintings eventually formed the collection that is now known as the Museo Sorolla , which was the artist's house in Madrid. The museum opened in 1932. Sorolla's work is represented in museums throughout Spain, Europe, America, and in many private collections in Europe and America. In 1933, J. Paul Getty purchased ten Impressionist beach scenes made by Sorolla, several of which are now housed in
4850-653: The United States in the early twentieth century. The exhibition opened at the Meadows Museum at SMU in Dallas (13 December 2013 – 19 April 2014). From there it traveled to the San Diego Museum of Art (30 May – 26 August 2014) and then to Fundación MAPFRE in Madrid (23 September 2014 – 11 January 2015). In 2016 the Munich Kunsthalle held a major Sorolla exhibition. In 2019
4947-419: The Valencian Community regarding its status as a glottonym or as an independent language, since official reports show that the majority of the people in the Valencian Community consider it as a separate language, different from Catalan , although the same studies show that this percentage decreases among younger generations and people with higher studies. According to the 2006 Statute of Autonomy , Valencian
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#17327763493105044-404: The Valencian Community, including the television channel À Punt, which started broadcasting in June 2018. Linguists, including Valencian scholars, deal with Catalan and Valencian as the same language. The official regulating body of the language of the Valencian community, the Valencian Language Academy ( Acadèmia Valenciana de la Llengua, AVL) considers Valencian and Catalan to be two names for
5141-404: The Valencian Statute of Autonomy sets the legal status of Valencian, establishing that: Passed in 1983, the Law on the Use and Teaching of Valencian develops this framework, providing for the implementation of a bilingual educational system, regulating the use of Valencian in the public administration and judiciary system, where citizens can freely use it when acting before both, or establishing
5238-449: The Valencian people in their own language. It was reopened again in 2018 in the same location but under a different name, À Punt, and it is owned by À Punt Media, a group owned by the Generalitat Valenciana . The new television channel claims to be plural, informative and neutral for all of the Valencian population. It is bilingual, with a focus on the Valencian language. It is recognised as a regional TV channel. Prior to its dissolution,
5335-487: The Valencian-speaking domain, as well as words shared with other Catalan varieties, especially with North-Western ones . Words are rarely spread evenly over the Valencian Community, but are usually contained to parts of it, or spread out into other dialectal areas. Examples include hui 'today' (found in all of Valencia except transitional dialects, in Northern dialects avui ) and espill 'mirror' (shared with North-Western dialects, Central Catalan mirall ). There
5432-617: The WHO's African and Eastern Mediterranean regions. Serological tests for syphilis were introduced in 1906, and it was later shown that transmission occurred from the mother. Untreated early syphilis infections results in a high risk of poor pregnancy outcomes, including saddle nose , lower extremity abnormalities, miscarriages , premature births , stillbirths , or death in newborns . Some infants with congenital syphilis have symptoms at birth, but many develop symptoms later. Symptoms may include rash, fever, large liver and spleen , and skeletal abnormalities. Newborns will typically not develop
5529-489: The administration of RTVV under the People's Party (PP) had been controversial due to accusations of ideological manipulation and lack of plurality. The news broadcast was accused of giving marginal coverage of the Valencia Metro derailment in 2006 and the indictment of President de la Generalitat Francisco Camps in the Gürtel scandal in 2009. Supervisors appointed by the PP were accused of sexual harassment . In face of an increasing debt due to excessive expenditure by
5626-414: The affrication ( /t͡ʃ/ ) of initial and postconsonantal x (except in some cases) and the lenition (deaffrication) of tz /d͡z/ in most instances (especially the - itzar suffix). The Academy of Valencian Studies ( Acadèmia Valenciana de la Llengua , AVL), established by law in 1998 by the Valencian autonomous government and constituted in 2001, is in charge of dictating the official rules governing
5723-431: The age of 9 in his native town, and then under a succession of teachers including Cayetano Capuz, Salustiano Asenjo. At the age of eighteen he travelled to Madrid , vigorously studying master paintings in the Museo del Prado . After completing his military service, Sorolla, at age twenty-two, obtained a grant which enabled a four-year term to study painting in Rome , Italy , where he was welcomed by and found stability in
5820-478: The appointment of José María Aznar as Prime Minister of Spain . Zaplana has denied this, claiming that "[n]ever, never, was I able to negotiate that which is not negotiable, neither that which is not in the negotiating scope of a politician. That is, the unity of the language". The AVL orthography is based on the Normes de Castelló , a set of rules for writing Valencian established in 1932. A rival set of rules, called Normes del Puig , were established in 1979 by
5917-441: The availability of media in the Valencian language is extremely limited. All the other autonomous communities in Spain , including the monolingual ones, have public-service broadcasters, with the Valencian Community being the only exception despite being the fourth most populated. In July 2016 a new public corporation, Valencian Media Corporation , was launched in substitution of RTVV. It manages and controls several public media in
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#17327763493106014-441: The broadcast, starting a campaign against the PP. Nou TV's last broadcast ended abruptly when Spanish police pulled the plug at 12:19 on 29 November 2013. Having lost all revenues from advertisements and facing high costs from the termination of hundreds of contracts, critics question whether the closure of RTVV has improved the financial situation of the Generalitat, and point out to plans to benefit private-owned media. Currently,
6111-434: The cultural association Lo Rat Penat . Valencian is classified as a Western dialect, along with the North-Western varieties spoken in Western Catalonia ( Province of Lleida and most of the Province of Tarragona ). The various forms of Catalan and Valencian are mutually intelligible (ranging from 90% to 95%) Despite the position of the official organisations, an opinion poll carried out between 2001 and 2004 showed that
6208-419: The direction of his mature output. Sorolla painted two masterpieces in 1897 linking art and science: Portrait of Dr. Simarro at the microscope and A Research . These paintings were presented at the National Exhibition of Fine Arts held in Madrid in that year and Sorolla won the Prize of Honor. Here, he presents his friend Simarro as a man of science who transmits his wisdom investigating and, in addition, it
6305-420: The disease worldwide. Of the 660,000 congenital syphilis cases reported in 2016, 143,000 resulted in deaths of unborn babies, 61,000 deaths of newborn babies, 41,000 low birth weights or preterm births, and 109,000 young children diagnosed with congenital syphilis. Around 75% were from the WHO's African and Eastern Mediterranean regions. Cases of congenital syphilis in the United States have been rising since
6402-419: The drafting of the European Constitution , the regional governments of Spain where a language other than Spanish is co-official were asked to submit translations into the relevant language in question. Since different names are used in Catalonia ("Catalan") and in the Valencian Community ("Valencian"), the two regions each provided one version, which were identical to each other. Congenital syphilis It
6499-454: The duration between the infection of the mother and conception , the better the outcome for the infant including less chance of stillbirth or developing congenital syphilis. The Centers for Disease Control and Prevention recommends treating symptomatic or babies born to an infected mother with unknown treatment status with procaine penicillin G, 50,000 U/kg dose IM a day in a single dose for 10 days. Treatment for these babies can vary on
6596-410: The early 2010s. The Centers for Disease Control and Prevention (CDC) reported 918 cases for 2017, which is more than twice the yearly incidence of the preceding four years. The incidence in the United States has increased by 754% from 2012 to 2021 with a higher incidence seen in those with a lower socioeconomic status, as well as Black people, Native Americans and Native Hawaiians. Reports in 2023 show
6693-644: The example of Francisco Pradilla , the director of the Spanish Academy in Rome . A long sojourn to Paris in 1885 provided his first exposure to modern painting; of special influence were exhibitions of Jules Bastien-Lepage and Adolph von Menzel . Back in Rome he studied with José Benlliure, Emilio Sala , and José Villegas Cordero . In 1888, Sorolla returned to Valencia to marry Clotilde García del Castillo, whom he had first met in 1879, while working in her father's studio. By 1895, they had three children together: Maria, born in 1890, Joaquín, born in 1892, and Elena , born in 1895. In 1890, they moved to Madrid, and for
6790-438: The idea of traditional portraiture gives way to the sheer fluid delight of a painting constructed with thick passages of color, Sorolla's love of family and sunlight merged. Early in 1911, Sorolla visited the United States for a second time, and exhibited 152 new paintings at the Saint Louis Art Museum and 161 at the Art Institute of Chicago a few weeks later. Later that year Sorolla met Archie Huntington in Paris and signed
6887-479: The infant within 15 months of birth (with most titers being cleared by 6 months), and persistently elevated titers 6 months after birth should prompt investigation into neonatal syphilis including CSF analysis for neurosyphilis. Pleocytosis, raised CSF protein level and positive CSF serology suggest neurosyphilis. CSF VDRL is 50-90% specific for neurosyphilis. 60% of newborns with congenital syphilis also have neurosyphilis. Non-treponemal titers should be monitored in
6984-498: The influence of Velázquez was uppermost, as in My Family (1901), a reference to Las Meninas which grouped his wife and children in the foreground, the painter reflected, at work, in a distant mirror. At other times the desire to compete with his friend John Singer Sargent was evident, as in Portrait of Mrs. Ira Nelson Morris and her children (1911). A series of portraits produced in the United States in 1909, commissioned through
7081-627: The land of Valencia some years earlier is present, possibly for the first time in the history of painting, through the image of two affected children. The painting earned Sorolla his greatest official recognition, the Grand Prix and a medal of honor at the Universal Exhibition in Paris in 1900, and the medal of honor at the National Exhibition in Madrid in 1901. A series of preparatory oil sketches for Sad Inheritance
7178-467: The landscape and culture of its region, panoramas composed of throngs of laborers and locals. By 1917 he was, by his own admission, exhausted. He completed the final panel by July 1919. Sorolla suffered a stroke in 1920, while painting a portrait in his garden in Madrid. Paralysed for over four years, he died on 10 August 1923. He is buried in the Cementeri de Valencia, Spain. The Sorolla Room, housing
7275-405: The language has never been questioned since studies of the Romance languages , part of Valencian public opinion believes and affirms that Valencian and Catalan are different languages, an idea that began to spread during the turbulent Valencian transition by sectors of the regionalist right and by the so-called blaverisme (Blaverism). There is an alternative secessionist linguistic regulation,
7372-610: The legal entity of the Kingdom of Valencia for being the Mediterranean commercial power during the 14th and 15th centuries, becoming in the cultural and literary centre of the Crown of Aragon. Thus, the Valencians, together with the Majorcans, presented themselves to other peoples as Catalans while they referred to themselves as Valencians and Majorcans to themselves to emphasise the different legal citizenship of each kingdom. In
7469-525: The less specific Vision of Spain , eventually opting for a representation of the regions of the Iberian Peninsula , and calling it The Provinces of Spain . Despite the immensity of the canvases, Sorolla painted all but one en plein air , and travelled to the specific locales to paint them: Navarre , Aragon , Catalonia , Valencia , Elche , Seville , Andalusia , Extremadura , Galicia , Guipuzcoa , Castile , Leon , and Ayamonte , at each site painting models posed in local costume. Each mural celebrated
7566-419: The majority (65%) of the Valencian people (both Valencian and Spanish speakers) consider Valencian different from Catalan: this position is promoted by people who do not use Valencian regularly. Furthermore, the data indicate that younger people educated in Valencian speaking areas are considerably less likely to hold these views. According to an official poll in 2014, 54% of Valencians considered Valencian to be
7663-487: The most recent survey in 2021, there is a downward trend in everyday Valencian users. The lowest numbers are in the major cities of Valencia and Alicante , where the percentage of everyday speakers is at single-digit numbers. However, the percentage of residents who claim to be able to understand and read Valencian seems to have increased since 2015. Due to a number of political and social factors, including repression, immigration and lack of formal instruction in Valencian,
7760-460: The mother. Immunohistochemical staining or nucleic acid amplification of the amniotic fluid may also aid in the diagnosis. Diagnosis of syphilis in the neonate may be challenging as maternal treponemal antibodies (as non-treponemal titers) can cross the placenta and persist in the infant for many months after birth in the absence of neonatal syphilis, complicating the diagnosis. The passively transferred non-treponemal titers should be cleared from
7857-632: The mother. Failure of non-treponemal titers to decrease after treatment may indicate treatment failure or re-infection. A confirmed cure in the mother does not exclude the possibility of congenital syphilis as transmission to the fetus may have occurred prior to maternal cure. Diagnosis of congenital syphilis in the fetus is based on a combination of laboratory, imaging and physical exam findings. Ultrasound findings associated with congenital syphilis intrauterine infection (which are seen after 18 weeks gestation) include fetal hepatomegaly (enlarged liver)(seen in greater than 80% of cases), anemia (as measured by
7954-475: The nation I am from born can rejoice"). Since the Spanish democratic transition , the autonomy or heteronomy of Valencian with respect to the rest of the Valencian-Catalan linguistic system has been the subject of debate and controversy among Valencians, usually with a political background. Although in the academic field (universities and institutions of recognszed prestige) of linguists the unity of
8051-519: The newborns every 2-3 months to ensure an adequate response to treatment. If a pregnant mother is identified as being infected with syphilis, treatment can effectively prevent congenital syphilis from developing in the fetus, especially if she is treated before the sixteenth week of pregnancy or at least 30 days prior to delivery. Mothers with primary syphilis can be treated with a single dose of intramuscularly injected penicillin, whereas late-latent, secondary syphilis, or disease of an unknown duration
8148-447: The next decade Sorolla's efforts as an artist were focused mainly on the production of large canvases of orientalist , mythological, historical, and social subjects, for display in salons and international exhibitions in Madrid, Paris, Venice , Munich , Berlin , and Chicago . His first striking success was achieved with Another Marguerite (1892), which was awarded a gold medal at the National Exhibition in Madrid, then first prize at
8245-661: The number of speakers has severely decreased, and the influence of Spanish has led to the appearance of a number of barbarisms . This is a list of features of the main forms of Valencian. There is a great deal of variety within the Valencian Community, and by no means do the features below apply to every local version. For more general information about other linguistic varities, see Catalan language . The Acadèmia Valenciana de la Llengua (AVL) specifies Standard Valencian as having some specific syntax, vocabulary, verb conjugations and accent marks compared to Standard Catalan . Valencian vocabulary contains words both restricted to
8342-427: The peak systolic velocity of the middle cerebral artery)(33%), placentomegaly (an enlarged placenta)(27%), polyhydramnios (an excess of amniotic fluid in the amniotic sac)(12%) and hydrops fetalis (edema in the fetus)(10%). The absence of these ultrasound findings does not rule out congenital syphilis in the fetus. These ultrasound abnormalities usually resolve several weeks after successful treatment of syphilis in
8439-410: The province of Alicante are more prone to be against the unity of the language, especially in the areas where Valencian is not a mandatory language at schools. Later studies also showed that the results differ significantly depending on the way the question is posed. The ambiguity regarding the term Valencian and its relation to Catalan has sometimes led to confusion and controversy. In 2004, during
8536-632: The right to be informed by media in Valencian among others. Valencian is also protected under the European Charter for Regional or Minority Languages , ratified by Spain. However, the Committee of Experts of the Charter has pointed out a considerable number of deficiencies in the application of the Charter by the Spanish and Valencian governments. Unlike in other bilingual autonomous communities , Valencian has not historically been spoken to
8633-770: The same extent throughout the Valencian Community . Slightly more than a quarter of its territory, equivalent to 10-15% of the population (its inland and southernmost areas), is Spanish-speaking since the Middle Ages. Additionally, it is also spoken by a small number of people in the Carche comarca , a rural area in the Region of Murcia adjoining the Valencian Community. Nevertheless, Valencian does not have any official recognition in this area. Nowadays about 600 people are able to speak Valencian in Carche. The Valencian language
8730-409: The same language. [T]he historical patrimonial language of the Valencian people , from a philological standpoint, is the same shared by the autonomous communities of Catalonia and Balearic Islands , and Principality of Andorra . Additionally, it is the patrimonial historical language of other territories of the ancient Crown of Aragon [...] The different varieties of these territories constitute
8827-515: The use of Valencian. Currently, the majority of people who write in Valencian use this standard. Standard Valencian is based on the standard of the Institute of Catalan Studies ( Institut d'Estudis Catalans , IEC), used in Catalonia , with a few adaptations. This standard roughly follows the Castelló Norms ( Normes de Castelló ) from 1932, a set of othographic guidelines regarded as
8924-477: The varieties of this language spoken in the Valencian Community and Carche cannot be considered a single dialect restricted to these borders: the several dialects of Valencian (Alicante's Valencian, Southern Valencian, Central Valencian or Apitxat , Northern Valencian or Castellon's Valencian and Transitional Valencian) belong to the Western group of Catalan dialects. There is a political controversy within
9021-876: Was among the topics discussed during the First International Congress of the Catalan Language, held in Barcelona October 1906. Subsequently, the Philological Section of the Institut d'Estudis Catalans (IEC), founded in 1911, published the Normes ortogràfiques in 1913 under the direction of Antoni Maria Alcover and Pompeu Fabra . In 1932, Valencian writers and intellectuals gathered in Castelló de la Plana to make
9118-418: Was born on 27 February 1863 in Valencia , Spain. Sorolla was the eldest child born to a tradesman, also named Joaquín Sorolla, and his wife, Concepción Bastida. His sister, Concha, was born a year later. In August 1865, both children were orphaned when their parents died, possibly from cholera. They were thereafter cared for by their maternal aunt and uncle, a locksmith. He received his initial art education at
9215-470: Was incompletely treated, is classified as late congenital syphilis. The signs of late congenital syphilis tend to reflect early damage to developing tissues that does not become apparent until years later, such as Hutchinson's triad of Hutchinson's teeth (notched incisors), keratitis and deafness. Symptoms include: Treatment (with penicillin) before the development of late symptoms is essential. Clinical signs include: Death from congenital syphilis
9312-401: Was marked by the painting and exhibition of Sad Inheritance (1899, seen at right), an extremely large canvas, highly finished for public consideration. The subject was a depiction of crippled children bathing at the sea in Valencia, under the supervision of a monk. They are the victims of congenital syphilis the title implies, perhaps. Campos has suggested that the polio epidemic that struck
9409-422: Was painted with the greatest luminosity and bravura, and foretold an increasing interest in shimmering light and of a medium deftly handled. Sorolla thought well enough of these sketches that he presented two of them as gifts to American artists; one to John Singer Sargent , the other to William Merritt Chase . After this painting Sorolla never returned to a theme of such overt social consciousness. The exhibit at
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