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110-409: Hwang was best known for two articles published in the journal Science in 2004 and 2005, where he reported he had succeeded in creating human embryonic stem cells by cloning . However, soon after the first paper was released, an article in the journal Nature accused Hwang of having committed ethical violations by using eggs from his graduate students and from the black market . Although he denied

220-556: A Nobel Prize in Physiology or Medicine for research initially rejected by Nature and published only after Lauterbur appealed against the rejection, Nature acknowledged more of its own missteps in rejecting papers in an editorial titled, "Coping with Peer Rejection": [T]here are unarguable faux pas in our history. These include the rejection of Cherenkov radiation , Hideki Yukawa 's meson , work on photosynthesis by Johann Deisenhofer , Robert Huber and Hartmut Michel , and

330-587: A US$ 133 million project in the North African country to build a stem cell research center and transfer relevant technology. The project was canceled due to the 2011 Libyan civil war . In November 2015, a Chinese biotech company Boyalife Group announced that it would partner with Hwang's laboratory, Sooam Biotech , to open the world's largest animal cloning factory in Tianjin . The factory would aim to produce up to one million cattle embryos per year to meet

440-550: A natural history magazine and progressed to include more physical observational science and technical subjects and less natural history. The journal's name changed from its original title to Intellectual Observer: A Review of Natural History, Microscopic Research, and Recreative Science and then to the Student and Intellectual Observer of Science, Literature, and Art . While Recreative Science had attempted to include more physical sciences such as astronomy and archaeology ,

550-617: A consequence, the majority of submitted papers are rejected without review. According to Nature ' s original mission statement : It is intended, FIRST, to place before the general public the grand results of Scientific Work and Scientific Discovery; and to urge the claims of Science to a more general recognition in Education and in Daily Life; and, SECONDLY, to aid Scientific men themselves, by giving early information of all advances made in any branch of Natural knowledge throughout

660-517: A donation would have been "voluntary" as Hwang claimed in his scientific paper. At that time, Hwang denied that he had used his students' eggs. Hwang's team announced an even greater achievement a year later in May 2005, and claimed they had created 11 human embryonic stem cells using 185 eggs. His work, published in the June 17 issue of Science , was instantly hailed as a breakthrough in biotechnology because

770-675: A facility that was to be the world's leading stem cell research center. However, in November 2005, Gerald Schatten , a University of Pittsburgh researcher who had worked with Hwang for two years, made the surprise announcement that he had ceased his collaboration with Hwang. In an interview, Schatten commented that "my decision is grounded solely on concerns regarding oocyte (egg) donations in Hwang's research reported in 2004." Following an intense media probe, Roh Sung-il , one of Hwang's close collaborators and head of MizMedi Women's Hospital , held

880-419: A former scientist at his lab to fake data to make it look like there were 11 stem cell colonies. In a separate report, a former researcher told MBC that Hwang ordered him to fabricate photos to make it appear there were 11 separate colonies from only three. [...] University of Pittsburgh researcher Gerald Schatten has already asked that Science remove him as the senior author of the report, citing questions about

990-449: A human stem cell by cloning was next to impossible due to the complexity of primates. Hwang explained that his team used 242 eggs to create a single cell line. In May, Nature journal published an article stating that Hwang had used eggs taken from two of his graduate students, based on an interview with one of the students. The article raised the question of whether the students might have been pressured to give eggs and thus whether such

1100-465: A line by William Wordsworth : "To the solid ground of nature trusts the Mind that builds for aye". First owned and published by Alexander Macmillan , Nature was similar to its predecessors in its attempt to "provide cultivated readers with an accessible forum for reading about advances in scientific knowledge." Janet Browne has proposed that "far more than any other science journal of the period, Nature

1210-479: A long time. In 2016, Hwang's company was regularly cloning pigs which were genetically predisposed to certain diseases so that they could be used for testing pharmaceuticals, and cloning cattle which were highly valued for their meat. In total Sooam Biotech was reported to be producing roughly 500 cloned embryos a day from various species. They were also reported to be attempting to clone the Ethiopian wolf , one of

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1320-666: A measure of how many citations a journal generates in other works, was 42.778 in 2019 (as measured by Thomson ISI ). However, as with many journals, most papers receive far fewer citations than the impact factor would indicate. Nature 's journal impact factor carries a long tail. Studies of methodological quality and reliability have found that some high-prestige journals including Nature "publish significantly substandard structures", and overall "reliability of published research works in several fields may be decreasing with increasing journal rank". As with most other professional scientific journals, papers undergo an initial screening by

1430-481: A news conference on November 21. During the conference, Roh admitted that he had paid women US$ 1,400 each for donating their eggs which were later used in Hwang's research. Roh claimed Hwang was unaware of this, while the South Korean Ministry of Health asserted that no laws or ethical guidelines had been breached as there were no commercial interests involved. Hwang maintained that he was unaware that

1540-415: A post, thus avoiding full retribution and possibly dismissal if found at fault, while benefiting from an honorable voluntary resignation. On February 9, 2006, the university suspended Hwang's position as a professor, together with six other faculty members who participated in Hwang's team; Hwang was dismissed on March 20, 2006. On May 12, 2006, Hwang was indicted on charges of embezzlement and breach of

1650-495: A probe to the allegations surrounding him. The scandal took a dramatic turn on December 15, when Roh Sung-il, who had collaborated on the disputed paper, stated to media outlets that nine of those eleven lines had been faked; specifically, DNA tests illustrated that those nine lines shared identical DNA , implying that they had come from the same source. Roh stated that "Professor Hwang admitted to fabrication", and that he, Hwang, and another co-author had asked Science to withdraw

1760-547: A public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; Nature redoubled its efforts in explanatory and scientific journalism . The late 1980s and early 1990s saw the creation of a network of editorial offices outside of Britain and the establishment of ten new supplementary, speciality publications (e.g. Nature Materials ). Since the late 2000s, dedicated editorial and current affairs columns are created weekly, and electoral endorsements are featured. The primary source of

1870-817: A reduced fee. However, research articles published after 1997 are available for free (with online registration) one year after they are published i.e. delayed open access . Significant public-health related articles are also available for free, sometimes immediately after publication. AAAS members may also access the pre-1997 Science archives at the Science website, where it is called "Science Classic". Institutions can opt to add Science Classic to their subscriptions for an additional fee. Some older articles can also be accessed via JSTOR and ProQuest . The journal also participates in initiatives that provide free or low-cost access to readers in developing countries, including HINARI , OARE, AGORA , and Scidev.net . Other features of

1980-456: A second office in Cambridge , UK. The major focus of the journal is publishing important original scientific research and research reviews, but Science also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals , which focus on

2090-482: A shock and a disappointment" and announced that he was resigning his position as professor at the university. However, Hwang maintained that patient-matched stem cell technology remained in South Korea, and his countrymen would see it. Seoul National University said Hwang's resignation request would not be accepted, citing a university regulation that dictates that an employee under investigation may not resign from

2200-573: A specific field, Science and its rival Nature cover the full range of scientific disciplines . According to the Journal Citation Reports , Science ' s 2023 impact factor was 44.7. Studies of methodological quality and reliability have found that some high-prestige journals including Science "publish significantly substandard structures", and overall "reliability of published research works in several fields may be decreasing with increasing journal rank". Although it

2310-419: A theory which, during the latter half of the 19th century, received a great deal of criticism among more conservative groups of scientists. Perhaps it was in part its scientific liberality that made Nature a longer-lasting success than its predecessors. John Maddox , editor of Nature from 1966 to 1973 and from 1980 to 1995, suggested at a celebratory dinner for the journal's centennial edition that perhaps it

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2420-514: Is a British weekly scientific journal founded and based in London , England. As a multidisciplinary publication, Nature features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature . Nature

2530-418: Is no longer science fiction, but a fact of life." Following on the earlier success, on August 3, 2005, Hwang announced that his team of researchers had become the first team to successfully clone a dog, which was independently verified through genetic testing. The dog, an Afghan Hound , was named Snuppy . Shortly after his groundbreaking 2005 work, Hwang was appointed to head the new World Stem Cell Hub ,

2640-414: Is taken from a donor and the nucleus is removed from the egg, creating an enucleated egg. A cell, which contains DNA , is then taken from the animal being cloned. The enucleated egg is then fused together with the nucleus of the cloning subject's cell using electricity. This creates an embryo , which is implanted into a surrogate mother through in vitro fertilization . If the procedure is successful, then

2750-664: Is the journal of the AAAS, membership in the AAAS is not required to publish in Science . Papers are accepted from authors around the world. Competition to publish in Science is very intense, as an article published in such a highly cited journal can lead to attention and career advancement for the authors. Fewer than 7% of articles submitted are accepted for publication. Science was founded by New York journalist John Michels in 1880 with financial support from Thomas Edison and later from Alexander Graham Bell . (Edison received favorable editorial treatment in return, without disclosure of

2860-584: The Nature Clinical Practice series of journals, Nature Structural & Molecular Biology , Nature Chemistry , and the Nature Reviews series of journals. Since 2005, each issue of Nature has been accompanied by a Nature Podcast featuring highlights from the issue and interviews with the articles' authors and the journalists covering the research. It is presented by Kerri Smith and features interviews with scientists on

2970-602: The American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. Science is based in Washington, D.C., United States, with

3080-574: The Intellectual Observer broadened itself further to include literature and art as well. Similar to Recreative Science was the scientific journal Popular Science Review , created in 1862, which covered different fields of science by creating subsections titled "Scientific Summary" or "Quarterly Retrospect", with book reviews and commentary on the latest scientific works and publications. Two other journals produced in England prior to

3190-463: The Prince of Asturias Award for Communications and Humanity. Nature mostly publishes research articles. Spotlight articles are not research papers but mostly news or magazine style papers and hence do not count towards impact factor nor receive similar recognition as research articles. Some spotlight articles are also paid by partners or sponsors. The huge progress in science and mathematics during

3300-613: The Science website include the free " ScienceNow " section with "up to the minute news from science", and " ScienceCareers ", which provides free career resources for scientists and engineers. Science Express ( Sciencexpress ) provides advance electronic publication of selected Science papers. Science received funding for COVID-19 -related coverage from the Pulitzer Center and the Heising-Simons Foundation . Nature (journal) Nature

3410-767: The Scientist of the Year Award by the Korea Science Journalists Association and the Inchon Award . Until 2004, Hwang's main area of research remained in creating genetically modified livestock that included cows and pigs. During that period, Hwang claimed to have created a BSE -resistant cow (which has not been verified), and also stated his intention to clone a Siberian tiger . In February 2004, Hwang and his team announced that they had successfully created an embryonic stem cell by

Hwang Woo-suk - Misplaced Pages Continue

3520-423: The Student and Intellectual Observer in 1871. The Quarterly Journal , after undergoing a number of editorial changes, ceased publication in 1885. The Reader terminated in 1867, and finally, Scientific Opinion lasted a mere 2 years, until June 1870. Not long after the conclusion of The Reader , a former editor, Norman Lockyer , decided to create a new scientific journal titled Nature , taking its name from

3630-561: The Unite the Right rally to oppose the removal of a statue of Robert E. Lee , setting off violence in the streets and killing a young woman. When Nature posted a link to the editorial on Twitter , the thread quickly exploded with criticisms. In response, several scientists called for a boycott. On 18 September 2017, the editorial was updated and edited by Philip Campbell, the editor of the journal. When Paul Lauterbur and Peter Mansfield won

3740-480: The somatic cell nuclear transfer method, and published their paper in the March 12 issue of Science . Although Hwang had already established himself as an expert in animal cloning and secured celebrity status in South Korea in the late 1990s, his alleged sudden success came as a surprise because this was the first reported success in human somatic cell cloning. Until Hwang's claim, it was generally agreed that creating

3850-496: The structure of DNA , Nature did not send the paper out for peer review. John Maddox , Nature ' s editor, stated: "the Watson and Crick paper was not peer-reviewed by Nature ... the paper could not have been refereed: its correctness is self-evident. No referee working in the field ... could have kept his mouth shut once he saw the structure". An earlier error occurred when Enrico Fermi submitted his breakthrough paper on

3960-628: The 19th century was recorded in journals written mostly in German or French , as well as in English . Britain underwent enormous technological and industrial changes and advances particularly in the latter half of the 19th century. The most respected scientific journals of this time were the refereed journals of the Royal Society , which had published many of the great works from Isaac Newton and Michael Faraday to Charles Darwin . In addition,

4070-516: The AAAS and executive publisher of Science , stated that the journal was becoming increasingly international: "[I]nternationally co-authored papers are now the norm—they represent almost 60 percent of the papers. In 1992, it was slightly less than 20 percent." The latest editions of the journal are available online, through the main journal website, only to subscribers, AAAS members, and for delivery to IP addresses at institutions that subscribe; students, K–12 teachers, and some others can subscribe at

4180-530: The Creative Commons attribution-non-commercial-share alike unported licence for those articles in Nature journals that are publishing the primary sequence of an organism's genome for the first time. In 2008, a collection of articles from Nature was edited by John S. Partington under the title H. G. Wells in Nature, 1893–1946: A Reception Reader and published by Peter Lang . Nature also publishes

4290-541: The Hwang Woo-suk's company Sooam Biotech, they were planning to build a 200 million RMB (about US$ 32 million) factory in Tianjin, China to produce 100,000 cloned cattle per year to supply China's growing market for quality beef, starting in 2016. In 2015, Sooam Biotech cloned a male boxer puppy from a pet dog that had been dead for 12 days. This was the first time they had cloned a dog that had been dead for such

4400-650: The South Korean Supreme Court upheld its 2010 ruling. Since the controversy, Hwang has maintained a relatively low profile, but continues to work in scientific fields. As of September 2020, he worked at the Sooam Bioengineering Research Institute in Yongin , Gyeonggi Province , leading research efforts into creating cloned pig embryos and embryonic stem cell lines. In February 2011, Hwang visited Libya as part of

4510-743: The South Korean government canceled his financial support and barred him from engaging in stem cell research. Hwang was sentenced to a two years suspended prison sentence at the Seoul Central District Court on 26 October 2009, after being found guilty of embezzlement and bioethical violations but cleared of fraud . On the same day, CNN reported that the scientist in 2006 had admitted faking his findings after questions of impropriety had emerged. He had his conviction upheld but his suspended sentence reduced by 6 months on 15 December 2010 by an appeals court in South Korea. In 2014,

Hwang Woo-suk - Misplaced Pages Continue

4620-898: The activities of the International Scientific Unions." During the years 1945 to 1973, editorship of Nature changed three times, first in 1945 to A. J. V. Gale and L. J. F. Brimble (who in 1958 became the sole editor), then to John Maddox in 1965, and finally to David Davies in 1973. In 1980, Maddox returned as editor and retained his position until 1995. Philip Campbell became Editor-in-chief of all Nature publications until 2018. Magdalena Skipper has since become Editor-in-chief. In 1970, Nature first opened its Washington office; other branches opened in New York in 1985, Tokyo and Munich in 1987, Paris in 1989, San Francisco in 2001, Boston in 2004, and Hong Kong in 2005. In 1971, under John Maddox 's editorship,

4730-650: The case that removing such statues, and erasing names, runs the risk of "whitewashing history", and stated "Instead of removing painful reminders, perhaps these should be supplemented". The article caused a large outcry and was quickly modified by Nature. The article was largely seen as offensive, inappropriate, and by many, racist. Nature acknowledged that the article as originally written was "offensive and poorly worded" and published selected letters of response. The editorial came just weeks after hundreds of white supremacists marched in Charlottesville, Virginia , in

4840-690: The cells were allegedly created with somatic cells from patients of different age and gender, while the stem cell of 2004 was created with eggs and somatic cells from a single female donor. This meant every patient could receive custom-made treatment with no immune reactions. In addition, Hwang's claim meant that his team had boosted their success rate by 14 times and that this technology could be medically viable. Hwang made further headlines in May 2005 when he criticized U.S. President George W. Bush 's policy on embryonic stem cell research. Also, Time magazine named Hwang one of its "People Who Mattered 2004", stating that Hwang "has already proved that human cloning

4950-422: The charges at first, Hwang admitted the allegations were true in November 2005. Shortly after this, data from his human cloning experiments was revealed to have been falsified. On May 12, 2006, Hwang was charged with embezzlement and bioethics law violations after it emerged much of his stem cell research had been faked. The Korea Times reported on June 10, 2007, that Seoul National University fired him, and

5060-399: The charges to rest." Two major press conferences were held on Korean television networks on December 16, one with Hwang, followed by one with his former colleague, Roh Sung-il. Hwang started his press conference by claiming that the technology to make stem cells existed—not an explicit denial that the stem cell lines he used in his paper to Science were fakes. He, however, acknowledged

5170-582: The cloned stem cell really existed." On July 26, 2006, Hwang said in testimony that he spent part of 500 million won in private donations in attempts to clone extinct Russian mammoths and Korean tigers. An internal panel was set up in Seoul National University to investigate the allegation, and the probe was started on December 17, 2005. The panel sealed off Hwang's laboratory and conducted a thorough investigation, collecting testimonies from Hwang, Roh and other people who were involved with

5280-459: The cloning of a Korean cow, Jin-i , also without providing any scientifically verifiable data. Despite the notable absence of any of the scientific data needed to probe the validity of the research, Hwang's several claims were well-received by the South Korean media and public, who were attracted by Hwang's claim of immeasurable economic prospect that his research was said to be promising. The claims of his research results resulted in him being awarded

5390-416: The confirmation of scientific misconduct, on January 11, Science unconditionally retracted both of Hwang's papers. On January 12, 2006, Hwang held a press conference to apologize for the fiasco, but did not admit to cheating. Instead, he blamed other members of his research project for having deceived him with false data and alleged a conspiracy , saying that his projects had been sabotaged and that there

5500-516: The content. While it does, to an extent, provide free online access to articles, it is not a true open access scheme due to its restrictions on re-use and distribution. On 15 January 2015, details of a proposed merger with Springer Science+Business Media were announced. In May 2015 it came under the umbrella of Springer Nature , by the merger of Springer Science+Business Media and Holtzbrinck Publishing Group 's Nature Publishing Group , Palgrave Macmillan , and Macmillan Education . Since 2011,

5610-510: The contents of the paper, can retract his name unilaterally, after publication." Several prominent scientists, including Ian Wilmut , who cloned Dolly the sheep in 1996, and Bob Lanza , a cloning expert based in Worcester, Massachusetts , did call on Hwang to submit his paper to an outside group for independent analysis. Lanza noted, "You can't fake the results if they're carried out by an independent group. I think this simple test could put

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5720-399: The country's bioethics law, without physical detention . Prosecutors also brought fraud charges against the three stem cell researchers. He embezzled 2.8 billion won (US$ 3 million) out of some 40 billion won in research funds, for personal purposes and the illegal purchase of ova used in his experiments. Science (journal) Science is the peer-reviewed academic journal of

5830-672: The development of Nature were the Quarterly Journal of Science and Scientific Opinion , established in 1864 and 1868, respectively. The journal most closely related to Nature in its editorship and format was The Reader , created in 1863; the publication mixed science with literature and art in an attempt to reach an audience outside of the scientific community, similar to Popular Science Review . These similar journals all ultimately failed. The Popular Science Review survived longest, lasting 20 years and ending its publication in 1881; Recreative Science ceased publication as

5940-599: The early part of the 20th century, important articles published in Science included papers on fruit fly genetics by Thomas Hunt Morgan , gravitational lensing by Albert Einstein , and spiral nebulae by Edwin Hubble . After Cattell died in 1944, the ownership of the journal was transferred to the AAAS. After Cattell's death in 1944, the journal lacked a consistent editorial presence until Graham DuShane became editor in 1956. In 1958, under DuShane's leadership, Science absorbed The Scientific Monthly , thus increasing

6050-493: The editor of Science in 2000. Biochemist Bruce Alberts took his place in March 2008. Geophysicist Marcia McNutt became editor-in-chief in June 2013. During her tenure the family of journals expanded to include Science Robotics and Science Immunology , and open access publishing with Science Advances . Jeremy M. Berg became editor-in-chief on July 1, 2016. Former Washington University in St. Louis Provost Holden Thorp

6160-411: The editor, followed by peer review (in which other scientists, chosen by the editor for expertise with the subject matter but who have no connection to the research under review, will read and critique articles), before publication. In the case of Nature , they are only sent for review if it is decided that they deal with a topical subject and are sufficiently ground-breaking in that particular field. As

6270-512: The egg extraction procedure. The panel stated that Hwang's 2004 Science paper was also fabricated and decided the stem cell discussed in the paper may have been generated by a case of parthenogenetic process (which is itself a significant development, as mammals rarely reproduce by parthenogenesis; in addition, this would make Hwang's lab the first ever to successfully generate human stem cells via parthenogenesis, predating other research facilities' successes). Although Hwang's team didn't rule out

6380-549: The eggs had been obtained via these methods, but regardless resigned from his post at the World Stem Cell Hub . On November 22, PD Su-cheop ( Producer's Note ), a popular MBC investigative reporting show, raised the possibility of unethical conduct in the egg cell-acquiring process. Despite the factual accuracy of the report, news media as well as people caught up in nationalistic fervor in their unwavering support for Hwang asserted that criticism of Hwang's work

6490-465: The eggs of surrogate mothers whose nuclei had been removed), making Snuppy the first ever dog to be cloned. The panel, in conclusion, stated that Hwang's team intentionally fabricated the data in both the 2004 and the 2005 papers, as described by Myung Hee Chung (Head of Seoul National University's investigation) and that it was an act of "deception of the scientific community and the public at large". On December 23, 2005, Hwang apologized for "creating

6600-489: The falsifications of research data in the paper, attributing them to unrecoverable "artificial mistakes". He said that there was a problem with the original lines caused by contamination , and if he were given ten more days he could re-create the stem cell lines. He accused Kim Sun-Jong, a former collaborator, of "switching" some of the stem cell lines. Despite Hwang's claim, in another press conference held only minutes later, Roh Sung-il rebutted Hwang's accusation, saying Hwang

6710-447: The financial relationship, at a time when his reputation was suffering due to delays producing the promised commercially viable light bulb.) However, the journal never gained enough subscribers to succeed and ended publication in March 1882. Alexander Graham Bell and Gardiner Greene Hubbard bought the magazine rights and hired young entomologist Samuel H. Scudder to resurrect the journal one year later. They had some success while covering

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6820-592: The first human embryo to use for research, said they had used the same technology to create batches of embryonic stem cells from nine patients. According to Hwang, the result was much more efficient than they had hoped. Hwang's integrity as a researcher was again put in doubt when it was revealed that PD Su-cheop had scheduled a follow-up report questioning his achievement published in Science in June 2005, which stated he had cloned 11 lines of embryonic stem cells. This caused furious backlash among many South Koreans, and

6930-464: The founder of Nature , was a professor at Imperial College . He was succeeded as editor in 1919 by Sir Richard Gregory . Gregory helped to establish Nature in the international scientific community. His obituary by the Royal Society stated: "Gregory was always very interested in the international contacts of science, and in the columns of Nature he always gave generous space to accounts of

7040-637: The increasing demand for quality beef in China. Hwang first caught media attention in South Korea when he announced he had successfully created a cloned dairy cow, Yeongrong-i in February 1999. His alleged success was touted as the fifth instance in the world in cow cloning, with a notable caveat: Hwang failed to provide scientifically verifiable data for the research, giving only media sessions and photo ops . Hwang's next claim came in April 1999, when he announced

7150-456: The initial rejection (but eventual acceptance) of Stephen Hawking 's black-hole radiation . In June 1988, after nearly a year of guided scrutiny from its editors, Nature published a controversial and seemingly anomalous paper detailing Jacques Benveniste and his team's work studying water memory . The paper concluded that less than a single molecule of antibody diluted in water could trigger an immune response in human basophils , defying

7260-474: The journal as either letters or news articles. The papers that have been published in this journal are internationally acclaimed for maintaining high research standards. Conversely, due to the journal's exposure, it has at various times been a subject of controversy for its handling of academic dishonesty, the scientific method , and news coverage. Fewer than 8% of submitted papers are accepted for publication. In 2007, Nature (together with Science ) received

7370-672: The journal has published Nature's 10 "people who mattered" during the year, as part of their annual review. According to Science , another academic journal, being published in Nature has been known to carry a certain level of prestige in academia. In particular, empirical papers are often highly cited, which can lead to promotions, grant funding, and attention from the mainstream media. Because of these positive feedback effects, competition among scientists to publish in high-level journals like Nature and its closest competitor, Science , can be very fierce. Nature ' s impact factor ,

7480-696: The journal remains, as established at its founding, research scientists; editing standards are primarily concerned with technical readability. Each issue also features articles that are of general interest to the scientific community, namely business, funding, scientific ethics, and research breakthroughs. There are also sections on books, arts, and short science fiction stories. The main research published in Nature consists mostly of papers (articles or letters) in lightly edited form. They are highly technical and dense, but, due to imposed text limits, they are typically summaries of larger work. Innovations or breakthroughs in any scientific or technological field are featured in

7590-423: The journal split into Nature Physical Sciences (published on Mondays), Nature New Biology (published on Wednesdays), and Nature (published on Fridays). In 1974, Maddox was no longer editor, and the journals were merged into Nature . Starting in the 1980s, the journal underwent a great deal of expansion, launching over ten new journals. These new journals comprise Nature Research, which was created in 1999 under

7700-642: The journal's circulation by over 62% from 38,000 to more than 61,000. Physicist Philip Abelson , a co-discoverer of neptunium , served as editor from 1962 to 1984. Under Abelson the efficiency of the review process was improved and the publication practices were brought up to date. During this time, papers on the Apollo program missions and some of the earliest reports on AIDS were published. Biochemist Daniel E. Koshland Jr. served as editor from 1985 until 1995. From 1995 until 2000, neuroscientist Floyd E. Bloom held that position. Biologist Donald Kennedy became

7810-595: The latest research, as well as news reports from Nature 's editors and journalists. The Nature Podcast was founded – and the first 100 episodes were produced and presented – by clinician and virologist Chris Smith of Cambridge and The Naked Scientists . Nature Portfolio actively supports the self-archiving process and in 2002 was one of the first publishers to allow authors to post their contributions on their personal websites, by requesting an exclusive licence to publish, rather than requiring authors to transfer copyright. In December 2007, Nature Publishing Group introduced

7920-510: The lines Hwang claims to have created at Seoul-based MizMedi Hospital. On November 22, 2016, Hwang received a certificate of patent on NT-1 technology from the Korean Intellectual Property Office. In the late 1990s, the method that scientists used in cloning was somatic cell nuclear transfer , which is the same procedure that was used to create Dolly the sheep . This laboratory technique begins when an egg

8030-496: The meetings of prominent American scientific societies, including the AAAS. However, by 1894, Science was again in financial difficulty and was sold to psychologist James McKeen Cattell for $ 500 (equivalent to $ 17,610 in 2023). In an agreement worked out by Cattell and AAAS secretary Leland O. Howard , Science became the journal of the American Association for the Advancement of Science in 1900. During

8140-411: The name Nature Publishing Group and includes Nature , Nature Research Journals , Stockton Press Specialist Journals and Macmillan Reference (renamed NPG Reference). In 1996, Nature created its own website and in 1999 Nature Publishing Group began its series of Nature Reviews . Some articles and papers are available for free on the Nature website, while others require the purchase of premium access to

8250-563: The number of popular science periodicals doubled from the 1850s to the 1860s. According to the editors of these popular science magazines, the publications were designed to serve as "organs of science", in essence, a means of connecting the public to the scientific world. Nature , first created in 1869, was not the first magazine of its kind in Britain. One journal to precede Nature was Recreative Science: A Record and Remembrancer of Intellectual Observation , which, created in 1859, began as

8360-483: The panel discovered that Hwang's team was supplied with 2,061 eggs in the period of November 28, 2002, to December 8, 2005. Hwang's claim of not having known about the donation of eggs by his own female researchers was also denied by the panel; in fact, it was discovered that Hwang himself had distributed egg donation consent forms to his researchers and personally escorted one to the MizMedi Hospital to perform

8470-520: The paper's accuracy. Seoul National University announced this week it would conduct an internal probe into Hwang's research." Some scientists have started questioning Hwang's earlier work published in Science in February 2004, in which he claimed to have cloned embryonic stem cells. Maria Biotech head Park Se-pill said, "Up until now, I have believed Hwang did derive cloned embryonic stem cells although he admitted to misconduct in his follow-up paper on patient-specific stem cells...Now, I am not sure whether

8580-606: The paper, stating as a reason that there were "allegations from someone involved with the experiments that certain elements of the report may be fabricated." In the midst of national confusion, Hwang disappeared from public sight, to be hospitalized days later for alleged stress-related fatigue, while public opinion gradually began to turn against Hwang with even the major Korean companies who had withdrawn their support from PD Su-cheop reportedly now less than pleased with Hwang. Days later, Hwang started going to his laboratory while requesting Seoul National University to officially conduct

8690-437: The paper. Adding fuel to the fire, MBC broadcast the content of the canceled PD Su-cheop show, which substantiated Roh's claim. On the same day, The Seattle Times reported that Science had not yet received an official request from Hwang to withdraw the paper, and it had refused to remove Schatten's name from the paper, stating, "No single author, having declared at the time of submission his full and complete confidence in

8800-501: The photos of purportedly different cells were in fact photos of the same cell. Hwang responded that these additional photos were accidentally included and that there was no such duplication in the original submission to Science . This was later confirmed by the journal. Researchers raised questions about striking similarities between the DNA profiles of the cloned cells. Then collaborator Gerald Schatten asked Science to remove his name from

8910-548: The physical law of mass action . The paper excited substantial media attention in Paris, chiefly because their research sought funding from homeopathic medicine companies. Public inquiry prompted Nature to mandate an extensive and stringent experimental replication in Benveniste's lab, through which his team's results were refuted. Before publishing one of its most famous discoveries, Watson and Crick 's 1953 paper on

9020-489: The placement and maintenance of statues honouring scientists with known unethical, abusive and torturous histories. Specifically, the editorial called on examples of J. Marion Sims , the 'Father of gynecology' who experimented on African American female slaves who were unable to give informed consent, and Thomas Parran Jr. who oversaw the Tuskegee Syphilis Experiment . The editorial as written made

9130-449: The possibility of parthenogenetic process in the paper, the panel said, his team didn't make any conscientious effort to probe the possibility through the tests available. Chung Myunghee, the head of the panel, said at a news conference that the panel was not in a position to investigate Hwang's claim of his stem cells having been switched with MizMedi's, but added that such a claim was incomprehensible when there were no data to prove any of

9240-718: The potential to turn into many different types of cell and when they divide, each new cell has the potential to either remain a stem cell or become another type of cell with a more specialized function. According to stem cell biologists, it might be possible to harness this ability to turn stem cells into a super "repair kit" for the body, theoretically to use stem cells to generate healthy tissue to replace that either damaged by trauma or compromised by disease. The many conditions and illnesses that may eventually be treated by stem cell therapy include Parkinson's disease , Alzheimer's disease , heart disease , stroke , arthritis , diabetes , burns , and spinal cord damage. In March 2012, it

9350-518: The public expressed sympathy for Hwang. In mid-December, co-author of Hwang's papers came forward, telling the media that Hwang had confessed to fabricating evidence for nine of the eleven cell lines. He (Dr Roh Il-Sung) reportedly said he had doubts about the remaining two lines. On December 29, 2005, the university determined that all 11 of Hwang's stem cell lines were fabricated. The university announced on January 10, 2006, that Hwang's 2004 and 2005 papers in Science were both fabricated. Following on

9460-618: The public throughout the world, in a fashion that conveys their significance for knowledge, culture and daily life. Many of the most significant scientific breakthroughs in modern history have been first published in Nature . The following is a selection of scientific breakthroughs published in Nature , all of which had far-reaching consequences, and the citation for the article in which they were published. In 2017, Nature published an editorial entitled "Removing Statues of Historical figures risks whitewashing history: Science must acknowledge mistakes as it marks its past". The article commented on

9570-470: The reaction only intensified when it was discovered that Kim Sun-Jong, one of Hwang's researchers from MizMedi, had been coerced by illegal means to testify against Hwang. As a result, the scheduled broadcast was canceled and the network made a public apology to the nation, everyone more or less operating under the assumption that the show was at fault and not Hwang. Yet, other news outlets began to question Hwang's claims. Close scrutiny revealed that several of

9680-423: The scandal. On December 23, the panel announced its initial finding that Hwang had intentionally fabricated stem cell research results creating nine fake cell lines out of eleven, and added that the validity of two remaining cell lines is yet to be confirmed. The panel stated that Hwang's misconduct is "a grave act damaging the foundation of science." Hwang's claim of having used only 185 eggs to create stem cell lines

9790-494: The site. As of 2012 , Nature claimed an online readership of about 3 million unique readers per month. On 30 October 2008, Nature endorsed an American presidential candidate for the first time when it supported Barack Obama during his campaign in America's 2008 presidential election . In October 2012, an Arabic edition of the magazine was launched in partnership with King Abdulaziz City for Science and Technology . As of

9900-507: The situation only after it had occurred. He added that he had lied about the source of the eggs donated to protect the privacy of his female researchers, and that he was not aware of the Declaration of Helsinki , which clearly enumerates his actions as a breach of ethical conduct. After the press conference, which was aired on all major South Korean television networks, many of the nation's media outlets, government ministries, and members of

10010-431: The stem cells were ever made to begin with. However, the panel confirmed that Hwang's team had actually succeeded in cloning a dog they named Snuppy , as results from analyses of 27 markers that allowed distinguishing amongst extremely-inbred animals and of mitochondrial DNA sequencing indicated that Snuppy was a somatic cell clone of Tie (the dog who gave the somatic cells required for Snuppy, which were then inserted into

10120-459: The surrogate mother will give birth to a baby that is a clone of the cloning subject at the end of a normal gestation period. In 2014 researchers were reporting cloning success rates of seven to eight out of ten but in 1996 it took 277 attempts to create Dolly. Hwang allegedly used this technique at his laboratory in SNU to clone dogs during his experiments throughout the early 2000s. He claimed that it

10230-533: The time it was released, it had about 10,000 subscribers. On 2 December 2014, Nature announced that it would allow its subscribers and a group of selected media outlets to share links allowing free, "read-only" access to content from its journals. These articles are presented using the digital rights management system ReadCube (which is funded by the Macmillan subsidiary Digital Science), and does not allow readers to download, copy, print, or otherwise distribute

10340-498: The weak interaction theory of beta decay . Nature rejected the paper because it was considered too remote from reality. Fermi's paper was published by Zeitschrift für Physik in 1934. The journal apologised for its initial coverage of the COVID-19 pandemic in which it linked China and Wuhan with the outbreak, which may have led to racist attacks. From 2000 to 2001, a series of five fraudulent papers by Jan Hendrik Schön

10450-691: The world's rarest canids, of which there are only 500 in the wild, another endangered canid, the dhole , of which there only about 2,500 adults, and the Siberian musk deer , which is classified as vulnerable by the IUCN . Until late November 2005, Hwang was criticized only for unpublicized ethical violations. Colleagues and media outlets asserted that he had paid female donors for egg donations and that he had received donations from two junior researchers, both of which were violations. Later controversies centered around scientific misconduct . His team, which cloned

10560-430: The world, and by affording them an opportunity of discussing the various Scientific questions which arise from time to time. This was later revised to: First, to serve scientists through prompt publication of significant advances in any branch of science, and to provide a forum for the reporting and discussion of news and issues concerning science. Second, to ensure that the results of science are rapidly disseminated to

10670-475: Was retracted due to concerns raised regarding some of the panels shown in a figure, making it the most-cited retracted paper ever. In 1999, Nature began publishing science fiction short stories. The brief " vignettes " are printed in a series called "Futures". The stories appeared in 1999 and 2000, again in 2005 and 2006, and have appeared weekly since July 2007. Sister publication Nature Physics also printed stories in 2007 and 2008. In 2005, Nature

10780-499: Was "unpatriotic", so much so that the major companies who were sponsoring the show immediately withdrew their support. On November 24, Hwang held a press conference in Seoul, in which he declared his intention of resigning from most of his official posts. He also apologized for his actions and said, "I was blinded by work and my drive for achievement." He denied coercing his researchers into donating eggs and claimed that he found out about

10890-414: Was a clone. Since then Hwang and his associates have cloned many more dogs. In 2015, it was reported that Huang Woo-suk's company Sooam Biotech had produced 700 cloned puppies since 2005, with their owners paying about $ 100,000 each to have their dogs cloned. Hwang's intention to develop better technique for cloning was focused on stem cells because they are still at an early stage of development and retain

11000-687: Was also denied by the panel, which indicated that more eggs may have been used in the research process. The panel announced additional findings on December 29, and confirmed that no patient-matched embryonic stem cells existed, and that Hwang's team did not have the scientific data to prove any of the stem cells had ever been made. In its final report published on January 10, 2006, the panel reaffirmed its previous findings while announcing additional discoveries. The panel found out that, contrary to Hwang's claim of having used 185 eggs for his team's 2005 paper, at least 273 eggs were shown to have been used according to research records kept in Hwang's lab. In addition,

11110-518: Was announced that Hwang would collaborate with Russian scientists in an attempt to clone a woolly mammoth from remains found in Siberia . He had previously successful cloned eight coyotes in March 2011 using domestic dogs and grey wolves as surrogate mothers. However no mammoth sample fit for cloning had been found as of 2015. In 2015, the Chinese company BoyaLife announced that in partnership with

11220-1027: Was awarded the European Science Fiction Society 's Best Publisher award for the "Futures" series. One hundred of the Nature stories between 1999 and 2006 were published as the collection Futures from Nature in 2008. Another collection, Futures from Nature 2 , was published in 2014. Nature is edited and published in the United Kingdom by a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines , online databases, and services in science and medicine. Nature has offices in London, New York City, San Francisco, Washington, D.C., Boston , Tokyo, Hong Kong, Paris, Munich , and Basingstoke . Nature Portfolio also publishes other specialized journals including Nature Neuroscience , Nature Biotechnology , Nature Methods ,

11330-549: Was blackmailing MizMedi and Kim Sun-jong. He maintained that at least nine of the eleven stem cell lines were fakes and that Hwang was simply untrustworthy. "Roh Sung-il, chairman of the board at Mizmedi Hospital, told KBS television that Hwang had agreed to ask the journal Science to withdraw the paper, published in June to international acclaim. Roh was one of the co-authors of the article that detailed how individual stem cell colonies were created for 11 patients through cloning. Roh also told MBC television that Hwang had pressured

11440-610: Was conceived, born, and raised to serve polemic purpose." Many of the early editions of Nature consisted of articles written by members of a group that called itself the X Club , a group of scientists known for having liberal, progressive, and somewhat controversial scientific beliefs for their time. Initiated by Thomas Henry Huxley , the group consisted of such important scientists as Joseph Dalton Hooker , Herbert Spencer , and John Tyndall , along with another five scientists and mathematicians; these scientists were all avid supporters of Darwin's theory of evolution as common descent ,

11550-529: Was named editor-in-chief on Monday, August 19, 2019. In February 2001, draft results of the human genome were simultaneously published by Nature and Science with Science publishing the Celera Genomics paper and Nature publishing the publicly funded Human Genome Project . In 2007, Science (together with Nature ) received the Prince of Asturias Award for Communications and Humanity. In 2015, Rush D. Holt Jr. , chief executive officer of

11660-511: Was one of the world's most cited scientific journals by the Science Edition of the 2022 Journal Citation Reports (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals . As of 2012 , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, Nature was first circulated by Norman Lockyer and Alexander MacMillan as

11770-479: Was possible to clone mammals and that probability for success can be better than 1 in 277 attempts (as in similar cases such as Dolly). Hwang was the first in the world to clone a dog, an Afghan hound called Snuppy in 2005. He described his procedure for cloning in the journal Nature . Researchers from the Seoul National University and the US National Institutes of Health confirmed that Snuppy

11880-438: Was published in Nature . The papers, about semiconductors , were revealed to contain falsified data and other scientific fraud. In 2003, Nature retracted the papers. The Schön scandal was not limited to Nature ; other prominent journals, such as Science and Physical Review , also retracted papers by Schön. In 2024, a paper titled " Pluripotency of mesenchymal stem cells derived from adult marrow," published in 2002,

11990-480: Was the journalistic qualities of Nature that drew readers in; "journalism" Maddox states, "is a way of creating a sense of community among people who would otherwise be isolated from each other. This is what Lockyer's journal did from the start." In addition, Maddox mentions that the financial backing of the journal in its first years by the Macmillan family also allowed the journal to flourish and develop more freely than scientific journals before it. Norman Lockyer ,

12100-578: Was theft of materials involved. He said that cloning human stem cells was possible and that he had the technology to do it, and if he were given six more months he could prove it. This is an extension of the ten days he said he needed to re-create the stem cells that he asked for back on December 16, 2005. Seoul prosecutors started a criminal investigation and raided Hwang's home that day. On January 20, 2006, Hwang maintained that two of his 11 forged stem cell lines had been maliciously switched for cells from regular, not cloned, embryos. The allegation involves

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