The microfilaria (plural microfilariae , sometimes abbreviated mf ) is an early stage in the life cycle of certain parasitic nematodes in the family Onchocercidae . In these species, the adults live in a tissue or the circulatory system of vertebrates (the "definitive hosts" ). They release microfilariae into the bloodstream of the vertebrate host. The microfilariae are taken up by blood-feeding arthropod vectors (the " intermediate hosts "). In the intermediate host the microfilariae develop into infective larvae that can be transmitted to a new vertebrate host.
25-441: Phlebotomidae Psychodidae , also called drain flies , sink flies , filter flies , sewer flies , or sewer gnats , is a family of true flies . Some genera have short, hairy bodies and wings, giving them a "furry" moth-like appearance, hence one of their common names, moth flies . Members of the sub-family Phlebotominae , which are hematophagous (feed on blood), may be called sand flies in some countries, although this term
50-440: A known species because the adults are unknown, it is seldom used today. All parasites need a mechanism for spreading to new individual hosts. Parasites in the lower gastrointestinal tract usually shed eggs in the host feces. Tissue-dwelling parasites, such as Trichinella spiralis (cause of trichinosis ), rely on new hosts eating the tissues of their current host. For members of the family Onchocercidae whose adults live in
75-554: A lack of widespread consensus within the scientific community for extended periods. The continual publication of new data and diverse opinions plays a crucial role in facilitating adjustments and ultimately reaching a consensus over time. The naming of families is codified by various international bodies using the following suffixes: The taxonomic term familia was first used by French botanist Pierre Magnol in his Prodromus historiae generalis plantarum, in quo familiae plantarum per tabulas disponuntur (1689) where he called
100-595: A series of parallel veins without crossveins. The adults are typically nocturnal, though they orient themselves around lights and may appear to be attracted to light and odors. They are erratic fliers, and are often seen walking or running rapidly as well as taking flight. They are most active at night, but may also be seen during daylight, or near windows, lights, or illuminated display panels. The adults live for about 20 days, during which they will breed only once, often within hours of emerging from their pupal casings. Females will lay their eggs (between 30 and 100) just above
125-456: A small dark tube (a spiracle ) on their posterior end — they must regularly reach the surface to obtain oxygen. The larval stage lasts for between 9 and 15 days, depending on species, temperature, and environment. There are four instar stages. In small numbers, the larvae are sometimes considered beneficial, as their strong jaws can cut through the hair and sludge waste in drains which might otherwise form clogs. However, unless this sludge layer
150-567: Is also used for other unrelated flies. There are more than 2,600 described species worldwide, most of them native to the humid tropics. This makes them one of the most diverse families of their order. Drain flies sometimes inhabit plumbing drains and sewage systems, where they are harmless, but may be a persistent annoyance. The larvae of the subfamilies Psychodinae , Sycoracinae and Horaiellinae live in aquatic to semi-terrestrial or sludge-based habitats, including bathroom sinks, where they feed on bacteria and can become problematic. The larvae of
175-499: Is commonly referred to as the "walnut family". The delineation of what constitutes a family— or whether a described family should be acknowledged— is established and decided upon by active taxonomists . There are not strict regulations for outlining or acknowledging a family, yet in the realm of plants, these classifications often rely on both the vegetative and reproductive characteristics of plant species. Taxonomists frequently hold varying perspectives on these descriptions, leading to
200-485: Is one of the eight major hierarchical taxonomic ranks in Linnaean taxonomy . It is classified between order and genus . A family may be divided into subfamilies , which are intermediate ranks between the ranks of family and genus. The official family names are Latin in origin; however, popular names are often used: for example, walnut trees and hickory trees belong to the family Juglandaceae , but that family
225-444: Is removed entirely, the adult flies will continue to find it and lay more eggs. While the biting midges also have larvae that have no prolegs and which also have attachment disks, the larvae of the netwinged midges can be distinguished from those of the moth fly by the multiple deep lateral constrictions of the latter. The pupal stage lasts between 20 and 40 hours. During this stage, the insect does not feed, but stays submerged near
250-462: The Genera Plantarum of George Bentham and Joseph Dalton Hooker this word ordo was used for what now is given the rank of family. Families serve as valuable units for evolutionary, paleontological, and genetic studies due to their relatively greater stability compared to lower taxonomic levels like genera and species. Microfilaria The presence of microfilariae in
275-538: The "closed" vertebrate circulatory system , transmission to a new host is achieved by the microfilaria stage, with the help of blood-feeding arthropod vectors . This system is seen in the life cycle of Elaeophora schneideri . The adults of E. schneideri typically reside in the carotid artery of its parasitic life cycle 's definitive host , the mule deer . The female may be up to 12 cm (almost 5 inches) long, and releases microfilariae which measure 207 by 13 μm (or 0.008 by 0.00051 inches) into
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#1732783982039300-460: The arthropod vector (p. 364 ). Some consider them to be the first larval stage, such as "microfilariae; i.e. first larva (= L1)" (p. 361 ). In either case, the microfilaria is the stage which develops from the egg. In most tissue-dwelling species the eggs hatch in the uterus of the female, and the unsheathed microfilariae are released. In most blood-dwelling species, embryonated eggs (or, microfilariae which are said to be sheathed in
325-410: The bloodstream of the host. The blood flow carries the microfilariae away from the female in the carotid artery, and directly into the branching arteries of the head and face. Because of their size, the microfilariae pass easily through successively smaller vessels, becoming physically lodged in the small capillaries near the skin surface of the face and head. Attracted by the carbon dioxide exhaled by
350-535: The body segments are divided into a series of rings called annuli (singular is annulus ). Some of these rings will have characteristic plates on the dorsal side. The larval thorax is not significantly larger than the abdomen, giving the larvae a more "worm-like" appearance than those of most aquatic insects. In some species, the larvae can secure themselves to surfaces of their environment using "attachment disks" on their ventral side. Like mosquito larvae, they cannot absorb oxygen through water, and instead breathe via
375-450: The envelope of the egg) are released; and they will only exsheath ("hatch") after being ingested by the arthropod intermediate host . All microfilariae burrow through the stomach wall after being eaten by the arthropod host, and develop into infective third stage (L3) larvae. Many of the organs of microfilariae are in a very early stage of development. For some species, the developmental fates of individual cells have been followed from
400-540: The family as a rank intermediate between order and genus was introduced by Pierre André Latreille in his Précis des caractères génériques des insectes, disposés dans un ordre naturel (1796). He used families (some of them were not named) in some but not in all his orders of "insects" (which then included all arthropods ). In nineteenth-century works such as the Prodromus of Augustin Pyramus de Candolle and
425-426: The host bloodstream is called "microfilaraemia". The success of filariasis eradication programs is typically gauged by the reduction in numbers of circulating microfilariae in infested individuals within a geographic area. Microfilaria may also refer to an informal "collective group" genus name, proposed by Cobbold in 1882. While a convenient category for newly discovered microfilariae which can not be assigned to
450-403: The microfilaria stage to the adult worm. The microfilariae of many species undergo a development phase called the "sausage stage", becoming temporarily shorter and thicker, while the first-stage (L1) larval organs develop. In some species of Onchocercidae, the release of microfilariae by the adult female is periodic—occurring daily at a particular time of the day or night. This timing increases
475-414: The microfilariae bore through the stomach wall, and mature into infective larvae about two weeks later. These larvae migrate to the head and mouthparts of the horse fly, and enter the bloodstream of another vertebrate host when the horse fly feeds again. Most recent parasitology textbooks consider the microfilariae to be "pre-larvae or advanced embryos" which will develop into the first stage larvae (L1) in
500-402: The most commonly encountered species are nearly transparent with a non-retractable black head and can sometimes be seen moving along the moist edges of crevices in shower stalls or bathtubs or submerged in toilet water. The larval form of the fly is usually between 4 and 5 mm (0.16 and 0.20 in) long, and is shaped like a long, thin, somewhat flattened cylinder. The body lacks prolegs, but
525-399: The mule deer, the blood-feeding female horse fly often lands on the head or face to feed. The horse fly uses its scissor-like mouthparts to cut the surface of the skin, creating a pool of blood which it takes in through its sucking mouthparts. The microfilariae, which were just under the surface of the skin, are small enough to be ingested whole by the horse fly. Once inside the horse fly,
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#1732783982039550-575: The seventy-six groups of plants he recognised in his tables families ( familiae ). The concept of rank at that time was not yet settled, and in the preface to the Prodromus Magnol spoke of uniting his families into larger genera , which is far from how the term is used today. In his work Philosophia Botanica published in 1751, Carl Linnaeus employed the term familia to categorize significant plant groups such as trees , herbs , ferns , palms , and so on. Notably, he restricted
575-549: The use of this term solely within the book's morphological section, where he delved into discussions regarding the vegetative and generative aspects of plants. Subsequently, in French botanical publications, from Michel Adanson 's Familles naturelles des plantes (1763) and until the end of the 19th century, the word famille was used as a French equivalent of the Latin ordo (or ordo naturalis ). In zoology ,
600-677: The water line inside moist drains. Within 48 hours these eggs hatch into drain worms, the larval form. The drain flies which are commonly found in bathrooms, Clogmia albipunctata , are not known to carry any human diseases, but have been known to be an opportunistic agent of myiasis . However, the subfamily of Phlebotominae does feed on blood with the ability to transmit (tropical) diseases, and Sycorax silacea can transmit microfilaria . Inhalation of insect fragments may cause asthma . This family has seven subfamilies that contain more than 2600 described species. Family (biology) Family ( Latin : familia , pl. : familiae )
625-476: The water surface, still breathing through a spiracle, and soon metamorphoses into an adult fly, which bursts through a seam in the pupal casing and emerges onto the water's surface. The adults are half as long as the larvae, but are much broader in appearance, with a pair of hairy wings held pitched-roof-like over the body. The wings have the most elementary venation of any of the Diptera, having little more than
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