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107-397: For the first time in its 67-year history, the show was cancelled for 2021 due to rising cases of COVID-19 . The show, originally called All Japan Motor Show was first held in an outdoor venue called Hibiya Park , the show was considered a success with 547,000 visitors over ten days and 254 exhibitors displaying 267 vehicles, but of the 267, only 17 of them were passenger cars as the show

214-494: A strain of coronavirus known as "severe acute respiratory syndrome coronavirus 2" ( SARS-CoV-2 ). COVID-19 is mainly transmitted when people breathe in air contaminated by droplets / aerosols and small airborne particles containing the virus. Infected people exhale those particles as they breathe, talk, cough, sneeze, or sing. Transmission is more likely the closer people are. However, infection can occur over longer distances, particularly indoors. The transmission of

321-597: A systemic inflammatory response syndrome . Among healthy adults not exposed to SARS-CoV-2, about 35% have CD4 T cells that recognise the SARS-CoV-2 S protein (particularly the S2 subunit) and about 50% react to other proteins of the virus, suggesting cross-reactivity from previous common colds caused by other coronaviruses. Ministry of International Trade and Industry The Ministry of International Trade and Industry ( 通商産業省 , Tsūshō-sangyō-shō , MITI )

428-402: A 1,500cc engine with a maximum output of 70 horse-power. In the truck category, The Nissan Datsun Truck G220 and many 3-wheeler models were highlighted. It was held from October 25 to November 7, 1960. It was held from October 25 to November 7, 1961. The "brilliant" Eighth Motor Show featured various sports cars and prototypes. The exhibiting area was double the space of the previous show and

535-408: A South Gate was newly added. An extended exhibition time (through 8 p.m.) was introduced on two days of this year's show. The total number of visitors surpassed 900,000. The Japanese government announced the " Income Doubling Plan " at the year-end of the previous year, and individual spending gradually increased. The so-called "3-C Period" was approaching the general public. People's dreams were to have

642-790: A car, color TV and air-conditioner. Buoyed by the upturned economy, the star models were presented at the Motor Show. Many international products were also showcased. They were the Prince Skyline Sports Convertible designed by Michelotti , the Nissan Fairlady prototype, the Italian-style Toyopet Sports X , and the Daihatsu 700cc engine car. It was held from October 25 to November 7, 1962. The highlight of this year's Motor Show

749-419: A certain critical size, generally thought to be <100μm diameter, evaporate faster than they settle; due to that fact, they form respiratory aerosol particles that remain airborne for a long period of time over extensive distances. Infectivity can begin four to five days before the onset of symptoms. Infected people can spread the disease even if they are pre-symptomatic or asymptomatic . Most commonly,

856-583: A hard time to develop. The company's advanced sports car fitted with the rotary engine was finally on the stage. It was held from September 26 to October 9, 1964. The Nissan Fairlady 1500 (Datsun Sports 1500, SR310) and the Mazda Cosmo were introduced at this show, one month before the 1964 Summer Olympics . Seeing market growth due to the liberalization of automobile import to be introduced in April next year, three foreign carmakers newly participated in

963-422: A higher risk of developing severe symptoms. Some complications result in death. Some people continue to experience a range of effects ( long COVID ) for months or years after infection, and damage to organs has been observed. Multi-year studies are underway to further investigate the long-term effects of the disease. COVID‑19 transmission occurs when infectious particles are breathed in or come into contact with

1070-404: A part of special-purpose vehicles only, which resulted in a passenger car oriented show this year. It was held from October 29 to November 11, 1971. The main focus of this year's show was the technological developments of safety vehicles and emission reduction, which were also the primary targets to be addressed. It was held from October 23 to November 5, 1972. The main focus of this year's show

1177-423: A range of effects, such as fatigue , for prolonged periods after an initial COVID-19 infection. This is the result of a condition called long COVID , which can be described as a range of persistent symptoms that continue for months or years. Long-term damage to organs has been observed after the onset of COVID-19. Multi-year studies are underway to further investigate the protracted effects of long COVID. Reducing

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1284-530: A regulator. A major objective of the ministry has been to strengthen the country's industrial base. It has not managed Japanese trade and industry along the lines of a centrally planned economy , but it has provided industries with administrative guidance and other direction, both formal and informal, on modernization, technology, investments in new plants and equipment, and domestic and foreign competition. The close relationship between MITI and Japanese industry has led to foreign trade policy that often complements

1391-410: A show for passenger cars and motorcycle in odd-numbered years and smaller shows for commercial vehicles in 2002 and 2004. However, from 2007 onwards the event has once again returned to a biennial schedule which combines both passenger and commercial vehicles, including motorcycles and auto parts. After several consecutive events with declining attendance, the 2019 Tokyo Motor Show recorded almost double

1498-646: A torque converter, and the Crown 1,500cc diesel engine model. The 1959 show opened on October 24 and ran until November 4, 1959. Notable premieres included Mitsubishi's first own passenger car, the Mitsubishi 500 . The Japan Trade Center (indoor exhibition hall), located in Harumi, was newly chosen as the venue for the Sixth Motor Show. The total area of the site was nearly three times that of Hibiya, while

1605-453: A variety of vehicles ranging from sporty models (including minivehicles) prepared for high-speed driving, cars for leisure use and city cars, as well as advanced reference models (including electric vehicles) focusing on high safety standards and low exhaust emissions. This year Toyota released the Celica and Carina onto the market, while Nissan launched its front-engine, front-wheel-drive model,

1712-744: Is a novel severe acute respiratory syndrome coronavirus. It was first isolated from three people with pneumonia connected to the cluster of acute respiratory illness cases in Wuhan. All structural features of the novel SARS-CoV-2 virus particle occur in related coronaviruses in nature, particularly in Rhinolophus sinicus (Chinese horseshoe bats). Outside the human body, the virus is destroyed by household soap which bursts its protective bubble . Hospital disinfectants, alcohols, heat, povidone-iodine , and ultraviolet -C (UV-C) irradiation are also effective disinfection methods for surfaces. SARS-CoV-2

1819-571: Is associated with COVID-19 and is reported in as many as 88% of symptomatic cases. Published data on the neuropathological changes related with COVID-19 have been limited and contentious, with neuropathological descriptions ranging from moderate to severe hemorrhagic and hypoxia phenotypes , thrombotic consequences, changes in acute disseminated encephalomyelitis (ADEM-type), encephalitis and meningitis . Many COVID-19 patients with co-morbidities have hypoxia and have been in intensive care for varying lengths of time, confounding interpretation of

1926-433: Is available, guidelines and recommendations for hypertensive patients remain. The effect of the virus on ACE2 cell surfaces leads to leukocytic infiltration, increased blood vessel permeability, alveolar wall permeability, as well as decreased secretion of lung surfactants. These effects cause the majority of the respiratory symptoms. However, the aggravation of local inflammation causes a cytokine storm eventually leading to

2033-402: Is because pregnant women with COVID‑19 appear to be more likely to develop respiratory and obstetric complications that can lead to miscarriage , premature delivery and intrauterine growth restriction . Fungal infections such as aspergillosis , candidiasis , cryptococcosis and mucormycosis have been recorded in patients recovering from COVID‑19. COVID‑19 is caused by infection with

2140-522: Is closely related to the original SARS-CoV . It is thought to have an animal ( zoonotic ) origin. Genetic analysis has revealed that the coronavirus genetically clusters with the genus Betacoronavirus , in subgenus Sarbecovirus (lineage B) together with two bat-derived strains. It is 96% identical at the whole genome level to other bat coronavirus samples (BatCov RaTG13 ). The structural proteins of SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and

2247-595: Is the cause of the bud release and the formation of the viral envelope. The N and E protein are accessory proteins that interfere with the host's immune response. Human angiotensin converting enzyme 2 (hACE2) is the host factor that SARS-CoV-2 virus targets causing COVID‑19. Theoretically, the usage of angiotensin receptor blockers (ARB) and ACE inhibitors upregulating ACE2 expression might increase morbidity with COVID‑19, though animal data suggest some potential protective effect of ARB; however no clinical studies have proven susceptibility or outcomes. Until further data

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2354-469: Is the viral component that attaches to the host receptor via the ACE2 receptors. It includes two subunits: S1 and S2. Studies have shown that S1 domain induced IgG and IgA antibody levels at a much higher capacity. It is the focus spike proteins expression that are involved in many effective COVID‑19 vaccines. The M protein is the viral protein responsible for the transmembrane transport of nutrients. It

2461-938: The Alpha variant (B.1.1.7, formerly called the UK variant), first found in London and Kent, the Beta variant (B.1.351, formerly called the South Africa variant), the Gamma variant (P.1, formerly called the Brazil variant), the Delta variant (B.1.617.2, formerly called the India variant), and the Omicron variant (B.1.1.529), which had spread to 57 countries as of 7 December. On December 19, 2023,

2568-755: The COVID-19 pandemic . The symptoms of COVID‑19 are variable but often include fever, fatigue, cough, breathing difficulties , loss of smell , and loss of taste . Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms . Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia ), while 14% develop severe symptoms ( dyspnea , hypoxia , or more than 50% lung involvement on imaging), and 5% develop critical symptoms ( respiratory failure , shock , or multiorgan dysfunction ). Older people are at

2675-588: The Spanish flu , Middle East respiratory syndrome , and Zika virus . In January 2020, the World Health Organization (WHO) recommended 2019-nCoV and 2019-nCoV acute respiratory disease as interim names for the virus and disease per 2015 guidance and international guidelines against using geographical locations or groups of people in disease and virus names to prevent social stigma . The official names COVID‑19 and SARS-CoV-2 were issued by

2782-482: The small intestine . The virus can cause acute myocardial injury and chronic damage to the cardiovascular system . An acute cardiac injury was found in 12% of infected people admitted to the hospital in Wuhan, China, and is more frequent in severe disease. Rates of cardiovascular symptoms are high, owing to the systemic inflammatory response and immune system disorders during disease progression, but acute myocardial injuries may also be related to ACE2 receptors in

2889-710: The spike protein (S). The M protein of SARS-CoV-2 is about 98% similar to the M protein of bat SARS-CoV, maintains around 98% homology with pangolin SARS-CoV, and has 90% homology with the M protein of SARS-CoV; whereas, the similarity is only around 38% with the M protein of MERS-CoV . The many thousands of SARS-CoV-2 variants are grouped into either clades or lineages . The WHO, in collaboration with partners, expert networks, national authorities, institutions and researchers, have established nomenclature systems for naming and tracking SARS-CoV-2 genetic lineages by GISAID , Nextstrain and Pango . The expert group convened by

2996-503: The "passenger cars" they dreamt of would gradually be getting closer to their lives. Passenger cars became the boom of the motor show, accordingly. Although only 527,000 people visited the fourth show between May 9 and May 19, 1957, significant vehicles made their debut; the first of the long running Toyota Corona and Prince Skyline were introduced, as well as a prototype of the Datsun Sports . The Fourth All-Japan Motor Show

3103-455: The 1950s and 1960s. As industry became stronger and as MITI lost some of its policy tools, such as control over allocation of foreign exchange, MITI's policies also changed. The success of Japanese exports and the tension it has caused in other countries led MITI to provide guidance on limiting exports of particular products to various countries. Starting in 1981, MITI presided over the establishment of voluntary restraints on automobile exports to

3210-531: The 1990s because of deregulation and the collapse of the Japanese asset price bubble , and the creation of the World Trade Organization made it more difficult for governments to protect local companies from foreign competition. The declining significance of MITI to Japanese companies made it a less powerful agency within the bureaucracy, and by the end of the 20th century, it was folded into

3317-501: The 5th Hall at the motor show to promote seatbelts (with demonstration) and control of idling. A "Traffic Safety Room for Children" was also created for the first time. Among the exhibits, Toyota's Crown Hardtop (2-door model) and Corona Mark II (1600 and 1900) were the center of attraction. Other vehicles of interest included the Nissan Laurel, Skyline 2000GT powered by a V6 engine, Isuzu 117 Coupe, and Toyota's Sprinter Coupe. It

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3424-548: The B.1 lineage. Several notable variants of SARS-CoV-2 emerged throughout 2020. Cluster 5 emerged among minks and mink farmers in Denmark . After strict quarantines and the slaughter of all the country's mink , the cluster was assessed to no longer be circulating among humans in Denmark as of 1 February 2021. As of December 2021 , there are five dominant variants of SARS-CoV-2 spreading among global populations:

3531-542: The CNS, possibly within an infected white blood cell. Research conducted when Alpha was the dominant variant has suggested COVID-19 may cause brain damage. Later research showed that all variants studied (including Omicron) killed brain cells, but the exact cells killed varied by variant. It is unknown if such damage is temporary or permanent. Observed individuals infected with COVID-19 (most with mild cases) experienced an additional 0.2% to 2% of brain tissue lost in regions of

3638-562: The COVID-19 infection may have different symptoms, and their symptoms may change over time. Three common clusters of symptoms have been identified: a respiratory symptom cluster with cough, sputum , shortness of breath , and fever; a musculoskeletal symptom cluster with muscle and joint pain, headache, and fatigue; and a cluster of digestive symptoms with abdominal pain, vomiting, and diarrhea. In people without prior ear, nose, or throat disorders, loss of taste combined with loss of smell

3745-455: The Cherry, featuring an industry-first horizontally mounted engine layout. A "Safety and Pollution Protection Center" pavilion was newly created at the show to indicate that the automotive industry has launched into the challenge to improve safety and reduce exhaust emissions. The 18th Tokyo Motor Show, the second international motor show, attracted many more visitors from overseas countries than

3852-666: The Daihatsu Fellow, and Suzuki Fronte featured significantly improved performance, resulting in a strong presence among owners of conventional minivehicles. Notably, the Nissan Prince Royal, the first made-in-Japan limousine used by the emperor and empress, was unveiled at the show. Visitors were surprised at the vehicle's overwhelming body size and engine. It was held from October 26 to November 8, 1967. The 14th Tokyo Motor Show provided an opportunity for promoting traffic safety to society. A "Traffic Safety Corner"

3959-517: The Japanese economy. By the mid-1980s, the ministry was helping foreign corporations set up operations in Japan. The decline of MITI was described by Johnstone: However MITI still continued to benefit industry, especially in semiconductors, where, to overcome resistance to a new technology, it forced every electronic company to have at least one CMOS project going. The influence of MITI shrank in

4066-585: The October 1 introduction of the automobile import liberalization. For this year's motor show, Japanese carmakers thus emphasized sales promotion rather than presenting showy exhibits. To cope with imported automobiles, luxury Japanese models were on display, including the President fitted with a V8 4,000cc engine, the New Cedric, and Crown V8 engine model which was previously showcased at last year's show. In

4173-486: The United States to allay criticism from American manufacturers and their unions. Similarly, MITI was forced to liberalize import policies, despite its traditional protectionist focus. During the 1980s, the ministry helped to craft a number of market-opening and import promoting measures, including the creation of an import promotion office within the ministry. The close relationship between MITI and industry allowed

4280-475: The WHO declared that another distinctive variant, JN.1, had emerged as a "variant of interest". Though the WHO expected an increase in cases globally, particularly for countries entering winter, the overall global health risk was considered low. The SARS-CoV-2 virus can infect a wide range of cells and systems of the body. COVID‑19 is most known for affecting the upper respiratory tract (sinuses, nose, and throat) and

4387-759: The WHO on 11 February 2020 with COVID-19 being shorthand for "coronavirus disease 2019". The WHO additionally uses "the COVID‑19 virus" and "the virus responsible for COVID‑19" in public communications. The symptoms of COVID-19 are variable depending on the type of variant contracted, ranging from mild symptoms to a potentially fatal illness. Common symptoms include coughing , fever , loss of smell (anosmia) and taste (ageusia), with less common ones including headaches , nasal congestion and runny nose , muscle pain , sore throat , diarrhea , eye irritation , and toes swelling or turning purple, and in moderate to severe cases, breathing difficulties . People with

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4494-551: The WHO recommended the labelling of variants using letters of the Greek alphabet , for example, Alpha , Beta , Delta , and Gamma , giving the justification that they "will be easier and more practical to discussed by non-scientific audiences". Nextstrain divides the variants into five clades (19A, 19B, 20A, 20B, and 20C), while GISAID divides them into seven (L, O, V, S, G, GH, and GR). The Pango tool groups variants into lineages , with many circulating lineages being classed under

4601-590: The attendance of the 2017 event, which was attributed to expanding the scope beyond automobiles. The 2021 event was cancelled due to the ongoing COVID-19 pandemic, The planned 2023 event will include other automobile-related industries and has been rebranded to the Japan Mobility Show . The first Tokyo Motor Show was held in Hibiya Park from April 20 to April 29, 1954. Of the 267 vehicles on display, only seventeen were passenger cars, which reflected

4708-515: The brain connected to the sense of smell compared with uninfected individuals, and the overall effect on the brain was equivalent on average to at least one extra year of normal ageing; infected individuals also scored lower on several cognitive tests. All effects were more pronounced among older ages. The virus also affects gastrointestinal organs as ACE2 is abundantly expressed in the glandular cells of gastric , duodenal and rectal epithelium as well as endothelial cells and enterocytes of

4815-591: The brain found as complications leading to death in people infected with COVID‑19. Infection may initiate a chain of vasoconstrictive responses within the body, including pulmonary vasoconstriction – a possible mechanism in which oxygenation decreases during pneumonia. Furthermore, damage of arterioles and capillaries was found in brain tissue samples of people who died from COVID‑19. COVID‑19 may also cause substantial structural changes to blood cells , sometimes persisting for months after hospital discharge. A low level of blood lymphocytess may result from

4922-428: The brains of those who have died from COVID‑19, but these results need to be confirmed. While virus has been detected in cerebrospinal fluid of autopsies, the exact mechanism by which it invades the CNS remains unclear and may first involve invasion of peripheral nerves given the low levels of ACE2 in the brain. The virus may also enter the bloodstream from the lungs and cross the blood–brain barrier to gain access to

5029-409: The clear jelly liquid found in lung autopsies of people who died of COVID-19. One possibility addressed in medical research is that hyuralonic acid (HA) could be the leading factor for this observation of the clear jelly liquid found in the lungs, in what could be hyuralonic storm, in conjunction with cytokine storm . One common symptom, loss of smell, results from infection of the support cells of

5136-584: The coming liberalization of automobile import, Japanese carmakers displayed an array of new cars," newspapers reported in regard to the Tenth Motor Show. As part of the 10th anniversary program, the admission fee for the first day of the show was set at 500 yen (100 yen fee plus 400 yen donation for the Community Chest Center).  From this year's show, two halls were provided for passenger car exhibits to help passenger cars become

5243-406: The data. Of people who show symptoms, 81% develop only mild to moderate symptoms (up to mild pneumonia ), while 14% develop severe symptoms ( dyspnea , hypoxia , or more than 50% lung involvement on imaging) that require hospitalization, and 5% of patients develop critical symptoms ( respiratory failure , septic shock , or multiorgan dysfunction ) requiring ICU admission. At least a third of

5350-539: The domestic market closed to most foreign companies. MITI lost some influence when the switch was made to a floating exchange rate between the United States dollar and yen in 1971. Before that point, MITI had been able to keep the exchange rate artificially low, which benefited Japan's exporters. Later, intense lobbying from other countries, particularly the United States , pushed Japan to introduce more liberal trade laws that further lessened MITI's grip over

5457-571: The exhibiting space was double that of Hibiya site. The admission fee, which comes with the lottery tickets, also was raised to 50 yen per person.  The number of exhibited vehicles expanded to 317 units in this year's show. In the passenger car category, Japanese automakers displayed attractive models, including the Subaru 360 , Mitsubishi 500 , Datsun Sports 211, and the all-new Bluebird. Toyota also presented its Mater Line equipped with Japan's first automatic transmission. The Prince Skyline featured

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5564-721: The expression of ACE-2, thereby facilitating the SARS-Cov2 virus to enter cells and to replicate. A competition of negative feedback loops (via protective effects of interferon alpha) and positive feedback loops (via upregulation of ACE-2) is assumed to determine the fate of patients suffering from COVID-19. Additionally, people with COVID‑19 and acute respiratory distress syndrome (ARDS) have classical serum biomarkers of CRS, including elevated C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer , and ferritin . Systemic inflammation results in vasodilation , allowing inflammatory lymphocytic and monocytic infiltration of

5671-428: The eyes, nose, or mouth. The risk is highest when people are in close proximity, but small airborne particles containing the virus can remain suspended in the air and travel over longer distances, particularly indoors. Transmission can also occur when people touch their eyes, nose or mouth after touching surfaces or objects that have been contaminated by the virus. People remain contagious for up to 20 days and can spread

5778-525: The face. While drugs have been developed to inhibit the virus, the primary treatment is still symptomatic , managing the disease through supportive care , isolation , and experimental measures . During the initial outbreak in Wuhan , the virus and disease were commonly referred to as "coronavirus" and "Wuhan coronavirus", with the disease sometimes called "Wuhan pneumonia". In the past, many diseases have been named after geographical locations, such as

5885-415: The first event after it changed to an every-other-year cycle, was held under the theme of "Life on Wheels" to present the auto industry's clear visions and attitude toward environmental issues. The Theme Pavilion put on various displays to show the broad connection of daily life and automobiles, as well as the auto industry's contribution (as an export business) to the Japanese economy. A very rare presentation

5992-684: The government sought a better mechanism for reviving the Japanese economy. MITI has been responsible not only in the areas of exports and imports but also for all domestic industries and businesses not specifically covered by other ministries in the areas of investment in plant and equipment, pollution control , energy and power , some aspects of foreign economic assistance, and consumer complaints. This span has allowed MITI to integrate conflicting policies, such as those on pollution control and export competitiveness, to minimize damage to export industries. MITI has served as an architect of industrial policy , an arbiter on industrial problems and disputes, and

6099-523: The heart. ACE2 receptors are highly expressed in the heart and are involved in heart function. A high incidence of thrombosis and venous thromboembolism occurs in people transferred to intensive care units with COVID‑19 infections, and may be related to poor prognosis. Blood vessel dysfunction and clot formation (as suggested by high D-dimer levels caused by blood clots) may have a significant role in mortality, incidents of clots leading to pulmonary embolisms , and ischaemic events (strokes) within

6206-503: The host cell. Following viral entry, COVID‑19 infects the ciliated epithelium of the nasopharynx and upper airways. Autopsies of people who died of COVID‑19 have found diffuse alveolar damage , and lymphocyte-containing inflammatory infiltrates within the lung. From the CT scans of COVID-19 infected lungs, white patches were observed containing fluid known as ground-glass opacity (GGO) or simply ground glass. This tended to correlate with

6313-528: The infection, children may develop paediatric multisystem inflammatory syndrome , which has symptoms similar to Kawasaki disease , which can be fatal. In very rare cases, acute encephalopathy can occur, and it can be considered in those who have been diagnosed with COVID‑19 and have an altered mental status. According to the US Centers for Disease Control and Prevention , pregnant women are at increased risk of becoming seriously ill from COVID‑19. This

6420-493: The key concepts of high-speed and safety. Notably, the president of the motor show Prince Takamatsu showed particular interest in such future cars displayed on the stages as Toyota's EX-I, II and III. Meanwhile, carmakers emphasized displays of technological developments at the show in response to recall problems reported in June this year. They also aggressively promoted countermeasures for some serious social issues: traffic safety and

6527-419: The light-duty truck category, advanced models were displayed, including Toyota's 4-wheel light truck SKB (1,000cc engine) which will be renamed as Toyoace in 1956, Nissan's Datsun 120 Truck and Fuji Seimitsu's 1.5-ton class 4-wheel truck. These models featured both excellent driving performance and handling stability that well outperform conventional 3-wheel light trucks. New passenger cars also were presented on

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6634-454: The lower respiratory tract (windpipe and lungs). The lungs are the organs most affected by COVID‑19 because the virus accesses host cells via the receptor for the enzyme angiotensin-converting enzyme 2 (ACE2), which is most abundant on the surface of type II alveolar cells of the lungs. The virus uses a special surface glycoprotein called a " spike " to connect to the ACE2 receptor and enter

6741-409: The lung and the heart. In particular, pathogenic GM-CSF-secreting T cells were shown to correlate with the recruitment of inflammatory IL-6-secreting monocytes and severe lung pathology in people with COVID‑19. Lymphocytic infiltrates have also been reported at autopsy. Multiple viral and host factors affect the pathogenesis of the virus. The S-protein , otherwise known as the spike protein,

6848-415: The majority of them were particularly interested in passenger cars. A poster of the motor show carried the slogan "Japanese Automobiles at a Glance!"  The Japanese government also had planned to release the national car at an affordable price range of around 250,000 yen. At that time, passenger cars were still very expensive for the general public in reality. At the same time, they had a premonition that

6955-487: The merger with Prince in 1966, announced a business tie-up with Fuji Heavy Industries. Toyota also formed a business alliance with Hino and Daihatsu. With this alliance, Hino stopped producing its Contessa passenger car and Hino vehicles vanished in the passenger car halls of the Tokyo Motor Show. As traffic safety and air-pollution became serious problems this year, the organizer provided a Safety Science Center in

7062-414: The ministry to play such a role in fostering more open markets, but conflict remained between the need to open markets and the desire to continue promoting new and growing domestic industries. As late as the 1980s, prime ministers were expected to serve a tenure as MITI minister before taking over the government. MITI worked closely with Japanese business interests, and was largely responsible for keeping

7169-424: The ministry's efforts to strengthen domestic manufacturing interests. MITI facilitated the early development of nearly all major industries by providing protection from import competition, technological intelligence, help in licensing foreign technology, access to foreign exchange, and assistance in mergers. These policies to promote domestic industry and to protect it from international competition were strongest in

7276-447: The moment a person first becomes infected and the appearance of the first symptoms. The median delay for COVID-19 is four to five days possibly being infectious on 1–4 of those days. Most symptomatic people experience symptoms within two to seven days after exposure, and almost all will experience at least one symptom within 12 days. Most people recover from the acute phase of the disease. However, some people continue to experience

7383-492: The motor show this year. With this international move, the motor show was renamed from the All-Japan Motor Show to the Tokyo Motor Show. A press room was also created for foreign and domestic media. This year's show featured many GT and Coupe models rather than conventional 4-door sedans, which reflected the desire for sporty cars in the minds of consumers. Toyota's third-generation Corona RT40 was also displayed at

7490-485: The motor show's stages. Toyota unveiled its 1.5-liter engine class small cars such as Toyopet Crown and Toyopet Master , while Nissan's Datsun 110 (860cc engine) also made its debut. These cars were signs of the start of the motorization of Japanese society with made-in-Japan brands. Meanwhile, the Imperial Prince visited the motor show for the first time. Passenger cars began to assume the greatest prominence at

7597-480: The olfactory epithelium , with subsequent damage to the olfactory neurons . The involvement of both the central and peripheral nervous system in COVID‑19 has been reported in many medical publications. It is clear that many people with COVID-19 exhibit neurological or mental health issues . The virus is not detected in the central nervous system (CNS) of the majority of COVID-19 patients with neurological issues . However, SARS-CoV-2 has been detected at low levels in

7704-432: The organisers decided to suspend the 1974 show due to the international energy crisis and the show became a biennial event. The show relocated to the convention and exhibition center Makuhari Messe in 1989, then its current venue Tokyo Big Sight in 2011. Due to high public demand for vehicles in everyday use and the fact that concept cars dominate the show, the show returned to being an annual event from 2001 to 2005 with

7811-533: The organizer was forced to change it to a one-way street. At the same time, maritime transport was introduced between Takeshiba Pier and Harumi. The exhibiting areas were extended to accommodate a total of 410 vehicles. A Technical Center also debuted in an out-door area at the show hosted by the Japan Automotive Service Equipment Association and others. It was held from October 26 to November 10, 1963. "To respond to

7918-466: The oxide catalyst (the three way catalyst was not available at that time) and Honda's CVCC engine, as well as Thermal Reactor technology developed by Mazda and Daihatsu. Meanwhile, visitors paid great attention to motor sport oriented cars such as a racecar specification model of the Nissan Skyline and Mazda Savanna RX-3 . A lunar surface vehicle, developed jointly by Isuzu and GM, was also one of

8025-652: The paucity of personal family transport in Japan at the time. Trucks , buses , and motorcycles made up most of the exhibits. Approximately 547,000 visitors attended the show over the ten days, where the most prominent cars were the Austin A40 , Hillman Minx and the newly introduced Renault 4CV , as well as domestic vehicles such as the Prince Sedan AISH , Toyota Toyopet Super RH ; Datsun Passenger Delux (Model DB-5) , Ohta Sedan and Van, and three-wheeled vehicles from Daihatsu . The second Tokyo Motor Show

8132-488: The peak viral load in upper respiratory tract samples occurs close to the time of symptom onset and declines after the first week after symptoms begin. Current evidence suggests a duration of viral shedding and the period of infectiousness of up to ten days following symptom onset for people with mild to moderate COVID-19, and up to 20 days for persons with severe COVID-19, including immunocompromised people. Severe acute respiratory syndrome coronavirus   2 (SARS-CoV-2)

8239-411: The people who are infected with the virus do not develop noticeable symptoms at any point in time. These asymptomatic carriers tend not to get tested and can still spread the disease. Other infected people will develop symptoms later (called "pre-symptomatic") or have very mild symptoms and can also spread the virus. As is common with infections, there is a delay, or incubation period , between

8346-433: The prevention of air-pollution. It was held from October 30 to November 12, 1970. Imported automobiles participated in the 17th Tokyo Motor Show for the first time. A total of 95 imported vehicles were exhibited by 33 foreign carmakers from 7 countries. The latest designs and advanced technologies of imported vehicles helped the Japan show to have a strong international flavor. On the other hand, Japanese carmakers presented

8453-409: The previous year when capital transaction was liberalized in Japan's automotive sector in April this year. Exhibits of carmakers this year also focused on the challenges and solutions for safety and low-emission vehicles to respond to increasing concerns of traffic safety, air-pollution, and traffic jams in society. As for commercial vehicles, approval for exhibition was given to the under 3-ton class and

8560-416: The respiratory tract, people with severe COVID‑19 have symptoms of systemic hyperinflammation. Clinical laboratory findings of elevated IL‑2 , IL‑6 , IL‑7 , as well as the following suggest an underlying immunopathology: Interferon alpha plays a complex, Janus-faced role in the pathogenesis of COVID-19. Although it promotes the elimination of virus-infected cells, it also upregulates

8667-859: The risk of long COVID includes staying up to date on the most recent COVID-19 vaccine, practicing good hygiene, maintaining clean indoor air, and physical distancing from people infected with a respiratory virus. Complications may include pneumonia , acute respiratory distress syndrome (ARDS), multi-organ failure , septic shock , and death. Cardiovascular complications may include heart failure, arrhythmias (including atrial fibrillation ), heart inflammation , thrombosis , particularly venous thromboembolism , and endothelial cell injury and dysfunction. Approximately 20–30% of people who present with COVID‑19 have elevated liver enzymes , reflecting liver injury. Neurologic manifestations include seizure , stroke, encephalitis , and Guillain–Barré syndrome (which includes loss of motor functions ). Following

8774-554: The show was also shifted to commence from October 10. The motor show hereafter opens as an autumn event organized by the Japan Motor Industrial Federation, Inc. In the fifth show, a Technical Center (sponsored by the Society of Automotive Engineering) was created to promote technical developments of made-in-Japan automobiles, as well as a new Meeting Place for business talks. An automobile information room

8881-407: The show. The Corona series and its long-time rival, Nissan's Bluebird, through their side-by-side competition in the so-called "B-C Battle" in the market, have long played a key role in the development of Japan's motorization. It was held from October 29 to November 11, 1965. A feeling that the time of high economic growth had come was in the air. The 12th Tokyo Motor Show was held immediately after

8988-517: The small car category, a variety of new models were unveiled in the 800-1,000cc engine class, including Japan's first fastback model, the Colt 800, the Honda S800/N800, Subaru 1000, and Familia Coupe 1000. My Cars (One's own cars), which were not used for taxi models, were also highlighted at the show. It was held from October 26 to November 8, 1966. The 13th Tokyo Motor Show was held in 1966,

9095-442: The star attraction. To commemorate the 20th anniversary, the organizer prepared special events for the Tokyo Motor Show this year. They were the "Development of Vehicles," an easy explanation display of how vehicles have progressed, and "Man and Automobiles," a review of the role of automobiles in society. It was held from October 30 to November 12, 1973. It was held from October 31 to November 10, 1975. The 21st Tokyo Motor Show,

9202-409: The stars of the motor show. A test driving course was created in the south of the exhibition area, which became very popular among visitors. This suggested that the show should include "an experience-oriented event." Many cars designed by foreign car designers were also displayed at the show. Notably, Toyo Kogyo (former Mazda Motor Corp.) unveiled its rotary engine series, which the company reportedly had

9309-504: The third Tokyo Motor Show which opened on April 20, 1956, over a 10-day period at Hibiya Park. This was primarily due to an initiative spearheaded by the Ministry of International Trade and Industry called the "people's car plan" or the "National Car Project", announced in May 1955. Although its stated target of a four-seat car capable of 100 km/h (62 mph) and available for ¥ 150,000

9416-516: The virus acting through ACE2-related entry into lymphocytes. Another common cause of death is complications related to the kidneys . Early reports show that up to 30% of hospitalised patients both in China and in New York have experienced some injury to their kidneys, including some persons with no previous kidney problems. Although SARS-CoV-2 has a tropism for ACE2-expressing epithelial cells of

9523-752: The virus even if they do not develop symptoms. Testing methods for COVID-19 to detect the virus's nucleic acid include real-time reverse transcription polymerase chain reaction (RT‑PCR), transcription-mediated amplification , and reverse transcription loop-mediated isothermal amplification (RT‑LAMP) from a nasopharyngeal swab . Several COVID-19 vaccines have been approved and distributed in various countries, many of which have initiated mass vaccination campaigns . Other preventive measures include physical or social distancing , quarantining , ventilation of indoor spaces, use of face masks or coverings in public, covering coughs and sneezes, hand washing , and keeping unwashed hands away from

9630-509: The virus is carried out through virus-laden fluid particles, or droplets, which are created in the respiratory tract, and they are expelled by the mouth and the nose. There are three types of transmission: "droplet" and "contact", which are associated with large droplets, and "airborne", which is associated with small droplets. If the droplets are above a certain critical size, they settle faster than they evaporate , and therefore they contaminate surfaces surrounding them. Droplets that are below

9737-586: The year of "The first year of My Car (one's own car)." As the driving force of the development of Japan's motorization, the Nissan Sunny and Toyota Corolla were unveiled at this year's show. Other carmakers also presented their new models in the 800-1,000cc engine class, heralding the "Era of Cars for Everyone." Amid the My Car boom, minivehicles fitted with under 660cc engines also earned popularity among consumers again. New minivehicle models such as Honda's N360,

9844-604: Was identified in Wuhan , China, in December 2019. Most scientists believe the SARS-CoV-2 virus entered into human populations through natural zoonosis , similar to the SARS-CoV-1 and MERS-CoV outbreaks, and consistent with other pandemics in human history. Social and environmental factors including climate change , natural ecosystem destruction and wildlife trade increased the likelihood of such zoonotic spillover . The disease quickly spread worldwide, resulting in

9951-475: Was Honda's first automobile. The company has already earned a world-class reputation in motorcycle races such as the World Grand Prix, and unveiled its two models on the stage: The Honda Sports 360 and 500. This helped the event attract one million and more visitors for the first time. The street from Ginza to the Harumi venue was congested with more than 10,000 cars going to the motor show every day and

10058-566: Was a ministry of the Government of Japan from 1949 to 2001. The MITI was one of the most powerful government agencies in Japan and, at the height of its influence, effectively ran much of Japanese industrial policy, funding research and directing investment. In 2001, MITI was merged with other agencies during the Central Government Reform to form the newly created Ministry of Economy, Trade and Industry (METI). MITI

10165-469: Was also provided near the main entrance of the venue. More than 300 people visited the center per day. Although some newspapers were critical, saying that a Japanese car for the common people had not yet been produced this year either, a newly released Subaru 360 was very popular at the national event. Other vehicles which aroused interest included the Mikasa Touring 600cc engine car equipped with

10272-525: Was also seen to show the various relationships between life and vehicles in the earlier days through such old vehicles as the 1918 "Detroit" electric vehicle and the 1929 Sumida bus. On the other hand, carmakers displayed the latest developments in environmental technology in order to comply with emission regulations. Toyota displayed the TTC-c/TTC-V system, while Nissan exhibited the NAPS system. The duration

10379-406: Was created on the second floor of the 8th Hall (space for passenger cars) to allow visitors to experience tests. At the 2nd Hall, another promotion was conducted concerning the importance of the helmet. Although the number of exhibited vehicles slightly decreased to 655 units, compared to the previous year, attractive vehicles were on display. Toyota's Century, fitted with a V8-cylinder 3,000cc engine,

10486-572: Was created with the split of the Ministry of Commerce and Industry in May 1949 and given the mission for coordinating international trade policy with other groups, such as the Bank of Japan , the Economic Planning Agency , and the various commerce-related cabinet ministries. At the time it was created, Japan was still recovering from the economic disaster of World War II . With inflation rising and productivity failing to keep up,

10593-597: Was dominated by commercial vehicles. In 1958, due to construction of a subway and underground parking lot near Hibiya Park, the show was shifted to the Korakuen Bicycle Racing Track. The show changed venues again in 1959 as the previous year was marred by heavy rain. It moved to an indoor facility, the newly opened Harumi Showplace which was three times the size of its previous venue. The 1962 show attracted more than 1 million visitors to view 410 vehicles from 284 exhibitors. Starting in 1973,

10700-600: Was held at Hibiya Park during an 11-day period from May 9. In the passenger car category, a significant improvement was found in the quality of exhibited vehicles, including the first-generation Toyopet Corona small car, Fuji Seimitsu's Prince Skyline, and the Nissan Datsun Sport prototype. In the truck category, Toyota displayed its first diesel truck (DA60), while Nissan unveiled its Nissan Junior and Nissan 581 models. Ohta also exhibited its 1.5-ton class light truck model. Meanwhile, an automobile information bureau

10807-524: Was held from October 24 to November 6, 1969. The Tomei Expressway opened in March this year and the demand for high-speed driving was growing rapidly in Japan. Significant progress was seen in the performance of Japanese vehicles. The 16th Tokyo Motor Show was highlighted by an array of sports cars and vehicles for motor sports. At the same time, many show models were displayed in the futuristic "dream cars" and commuter model categories, which were developed under

10914-466: Was held over twelve days, from May 7 to May 18, 1955. Almost 785,000 visitors attended, among them HIH Prince Akihito . The highlights of the passenger cars on display were the new Datsun 110 , Toyopet Crown RS and Toyopet Master RR . The Second All-Japan Motor Show was held in 1955 at Hibiya Park, the same venue as the previous year. The show was extended to 12 days. Exhibitors still focused on commercial vehicles, such as trucks, that year. Notably, in

11021-532: Was introduced as the company's flagship model. Nissan also unveiled its Bluebird 510. The vehicle features unique exterior design without triangle windows as well as a new independent 4-wheel suspension, which also became a popular model in the U.S. later. Toyo Kogyo displayed its rotary engine cars, the RX87 and RX85, as reference models. It was held from October 26 to November 11, 1968. Japanese carmakers experienced industry-wide reorganization this year. Nissan, after

11128-604: Was newly set up in the PR Center to provide extended knowledge on road traffic and vehicle design, etc. In this show, the organizer successfully provided visitors and exhibitors with an opportunity for business talks in addition to the general promotion of automobiles. It was held from October 10 to October 20, 1958. For the Fifth Motor Show, the venue was changed to the infield space of Korakuen Bicycle Race Stadium due to construction at Hibiya Park. The time period of

11235-440: Was shortened by 3 days to 11 days compared with the previous show. The exhibiting areas were also reduced to 5 Halls, which resulted in a reduction of visitors to the below-one-million-level for the first time since the 9th motor show. It was held from October 28 to November 7, 1977. COVID-19 Coronavirus disease 2019 ( COVID-19 ) is a contagious disease caused by the coronavirus SARS-CoV-2 . The first known case

11342-451: Was the technological developments of safety vehicles and emission reduction, which were also the primary targets to be addressed. The auto industry's challenging positions were highlighted throughout the show. To support this, a "Safety and Pollution Prevention Corner" was set up in the 1st Hall, while large commercial vehicles were eliminated from the exhibits again. Carmakers presented the latest technologies of low-emission vehicles, including

11449-443: Was unrealistic — despite being twice the national average income at the time, it was still only one fifth of what a typical vehicle cost — it was given credit as the spur for domestic automakers to strive to lower their prices. From this year, exhibited products have been grouped by vehicle type - truck, pickup truck, passenger car, 2-wheeler, and motorcycle. This measure was taken to provide more merits for visitors because

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