9-497: CACC may refer to: Calcium-activated chloride channel , a cellular ion signalling pathway Campaign against Climate Change , a UK pressure group that aims to raise public awareness of global warming through mobilising mass demonstrations A Canada (CA) Ministry of Health Communication Centre Center for Animal Care and Control , the non-profit operator of New York City's municipal shelter system Central Alabama Community College ,
18-552: A two-year institution of higher learning located in Alexander City, Alabama. Central Atlantic Collegiate Conference , a US intercollegiate athletic conference affiliated with the NCAA's Division II Citizens for Alternatives to Chemical Contamination, a Michigan environmental group Commercial Aircraft Corporation of China Ltd. , a Chinese company manufacturing large passenger aircraft Commander, Air Component Command,
27-517: A US military abbreviation (see 607th Air Intelligence Squadron ) Correlated Active Clause Coverage , A Logic Coverage Criterion from Software Testing Cooperative Adaptive Cruise Control , an extension of Adaptive Cruise Control in which vehicles exchange information Chin Association for Christian Communication , a non-profit organization for Chin people in Burma. Topics referred to by
36-649: Is different from Wikidata All article disambiguation pages All disambiguation pages Calcium-activated chloride channel The Calcium-Dependent Chloride Channel (Ca-ClC) proteins (or calcium-activated chloride channels (CaCCs), are heterogeneous groups of ligand-gated ion channels for chloride that have been identified in many epithelial and endothelial cell types as well as in smooth muscle cells . They include proteins from several structurally different families: chloride channel accessory (CLCA), bestrophin (BEST), and calcium-dependent chloride channel anoctamin (ANO or TMEM16) channels ANO1
45-478: Is highly expressed in human gastrointestinal interstitial cells of Cajal , which are proteins which serve as intestinal pacemakers for peristalsis . In addition to their role as chloride channels some CLCA proteins function as adhesion molecules and may also have roles as tumour suppressors . These eukaryotic proteins are "required for normal electrolyte and fluid secretion, olfactory perception, and neuronal and smooth muscle excitability" in animals. Members of
54-647: The Ca-CIC family are generally 600 to 1000 amino acyl residues (aas) in length and exhibit 7 to 10 transmembrane segments (TMSs). Tmc1 and Tmc2 ( TC#s 1.A.17.4.6 and 1.A.17.4.1 , respectively) may play a role in hearing and are required for normal function of cochlear hair cells, possibly as Ca channels or Ca channel subunits (see also family TC# 1.A.82 ). Mice lacking both channels lack hair cell mechanosensory potentials. There are 8 members of this family in humans, 1 in Drosophila and 2 in C. elegans . One of
63-555: The Ca-ClC family are: Cl (out) ⇌ Cl (in) and Cations (e.g., Ca ) (out) ⇌ Cations (e.g., Ca ) (in) CaCC s that are known to occur in humans include: As of this edit , this article uses content from "1.A.13 The Epithelial Chloride Channel (E-ClC) Family" , which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License , but not under
72-556: The latter two is expressed in mechanoreceptors. Tmc1 is a sodium-sensitive cation channel required for salt (Na ) chemosensation in C. elegans "where it is required for salt-evoked neuronal activity and behavioural avoidance of high concentrations of NaCl". TMEM16A is over-expressed in several tumor types. The role of TMEM16A in gliomas and the potential underlying mechanisms were analyzed by Liu et al. 2014. Knockdown of TMEM16A suppressed cell proliferation, migration and invasion. The reactions believed to be catalyzed by channels of
81-447: The same term [REDACTED] This disambiguation page lists articles associated with the title CACC . If an internal link led you here, you may wish to change the link to point directly to the intended article. Cliftonville Academy Cricket Club Retrieved from " https://en.wikipedia.org/w/index.php?title=CACC&oldid=1143492725 " Category : Disambiguation pages Hidden categories: Short description
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