The Crohn's Disease Activity Index or CDAI is a research tool used to quantify the symptoms of patients with Crohn's disease . This is of useful importance in research studies done on medications used to treat Crohn's disease; most major studies on newer medications use the CDAI in order to define response or remission of disease. As Crohn's disease is a disease with a variety of symptoms that affect quality of life , the quantification of symptoms may be of secondary importance to a quantitative assessment of the effect on quality of life. This has been addressed by the Inflammatory Bowel Disease Questionnaire (IBDQ) and other indices of quality of life for patients with Crohn's disease.
5-574: CDAI may refer to: Crohn's Disease Activity Index Cartilage-derived angiogenesis inhibitor Topics referred to by the same term [REDACTED] This disambiguation page lists articles associated with the title CDAI . If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=CDAI&oldid=791972456 " Category : Disambiguation pages Hidden categories: Short description
10-578: Is added for each set of complications: Remission of Crohn's disease is defined as CDAI below 150. Severe disease was defined as a value of greater than 450. Most major research studies on medications in Crohn's disease define response as a fall of the CDAI of greater than 70 points. The Harvey-Bradshaw index was devised in 1980 as a simpler version of the CDAI for data collection purposes. It consists of only clinical parameters: A score of less than 5
15-558: Is different from Wikidata All article disambiguation pages All disambiguation pages Crohn%27s Disease Activity Index The CDAI was developed by WR Best and colleagues from the Midwest Regional Health Center in Illinois , in 1976. It consists of eight factors, each summed after adjustment with a weighting factor. The components and weighting factors are the following: One point each
20-514: Is generally considered to represent clinical remission. A Simple Index of Crohn's disease activity has also been developed. While the CDAI is considered to be the gold standard for assessing disease activity in Crohn's disease, validation of the index has been varied. A key criticism of the CDAI is that it does not incorporate a subjective assessment of quality of life, endoscopic factors, or systemic features, such as fatigue into its calculation. The CDAI correlated well with protein loss in
25-471: The bowel in patients with protein losing enteropathy . As most symptoms of Crohn's disease broadly affect quality of life , attempts have been made to incorporate physical, social, and emotional performance characteristics into tests for severity of Crohn's disease . The Inflammatory Bowel Disease Questionnaire (IBDQ) was developed to incorporate elements of social, systemic and emotional symptoms, as well as bowel related symptoms into an activity index. In
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