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116-744: The Tiffanie is a cat breed similar to the Asian Shorthair except it has semi-long fur length. The breed belongs to the Asian Group and is generally recognised in any of the Asian Shorthair or Burmese colours and patterns. Like the other cats in the Asian Group, the breed was developed during the 1980s in the United Kingdom by crossbreeding a Persian Chinchilla and a Burmese . In cat registries that recognise
232-807: A Persian Chinchilla and a Burmese . It has full recognition in the GCCF , LOOF , SACC , preliminary status with the WCF , and has registration only status with The International Cat Association . The Australian Tiffanie is recognised by ANCATS and the Burmilla longhair by ACF , which are distinctly different in colour to the Asian Semi-longhair Tiffanie as these only come in silver or golden tipped or shaded . One governing body in Australia ( Waratah National Cat Alliance , WNCA, now
348-666: A family that had a common ancestor about 10 to 15 million years ago . The evolutionary radiation of the Felidae began in Asia during the Miocene around 8.38 to 14.45 million years ago . Analysis of mitochondrial DNA of all Felidae species indicates a radiation at 6.46 to 16.76 million years ago . The genus Felis genetically diverged from other Felidae around 6 to 7 million years ago . Results of phylogenetic research shows that
464-429: A helical structure (i.e., shaped like a corkscrew). Their double-helix model had two strands of DNA with the nucleotides pointing inward, each matching a complementary nucleotide on the other strand to form what look like rungs on a twisted ladder. This structure showed that genetic information exists in the sequence of nucleotides on each strand of DNA. The structure also suggested a simple method for replication : if
580-464: A nictitating membrane , allowing them to blink without hindering their vision. The domestic cat's hearing is most acute in the range of 500 Hz to 32 kHz. It can detect an extremely broad range of frequencies ranging from 55 Hz to 79 kHz, whereas humans can only detect frequencies between 20 Hz and 20 kHz. It can hear a range of 10.5 octaves , while humans and dogs can hear ranges of about 9 octaves. Its hearing sensitivity
696-534: A sexual process for transferring DNA from one cell to another cell (usually of the same species). Transformation requires the action of numerous bacterial gene products , and its primary adaptive function appears to be repair of DNA damages in the recipient cell. The diploid nature of chromosomes allows for genes on different chromosomes to assort independently or be separated from their homologous pair during sexual reproduction wherein haploid gametes are formed. In this way new combinations of genes can occur in
812-520: A "diagonal" gait: The diagonally opposite hind and fore legs move simultaneously. Cats are generally fond of sitting in high places or perching . A higher place may serve as a concealed site from which to hunt; domestic cats strike prey by pouncing from a perch such as a tree branch. Another possible explanation is that height gives the cat a better observation point, allowing it to survey its territory. A cat falling from heights of up to 3 m (9.8 ft) can right itself and land on its paws. During
928-582: A DNA molecule. In 1983, Kary Banks Mullis developed the polymerase chain reaction , providing a quick way to isolate and amplify a specific section of DNA from a mixture. The efforts of the Human Genome Project , Department of Energy, NIH, and parallel private efforts by Celera Genomics led to the sequencing of the human genome in 2003. At its most fundamental level, inheritance in organisms occurs by passing discrete heritable units, called genes , from parents to offspring. This property
1044-507: A cat's pupils expand to cover most of the exposed surface of its eyes. The domestic cat has rather poor color vision and only two types of cone cells , optimized for sensitivity to blue and yellowish green; its ability to distinguish between red and green is limited. A response to middle wavelengths from a system other than the rod cells might be due to a third type of cone. This appears to be an adaptation to low light levels rather than representing true trichromatic vision. Cats also have
1160-493: A complex trait is called heritability . Measurement of the heritability of a trait is relative—in a more variable environment, the environment has a bigger influence on the total variation of the trait. For example, human height is a trait with complex causes. It has a heritability of 89% in the United States. In Nigeria, however, where people experience a more variable access to good nutrition and health care , height has
1276-592: A cosegregation between the ASIP allele and coat black coloration. Cats have excellent night vision and can see at one sixth the light level required for human vision. This is partly the result of cat eyes having a tapetum lucidum , which reflects any light that passes through the retina back into the eye, thereby increasing the eye's sensitivity to dim light. Large pupils are an adaptation to dim light. The domestic cat has slit pupils , which allow it to focus bright light without chromatic aberration . At low light,
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#17327834428801392-483: A different parent. Many species have so-called sex chromosomes that determine the sex of each organism. In humans and many other animals, the Y chromosome contains the gene that triggers the development of the specifically male characteristics. In evolution, this chromosome has lost most of its content and also most of its genes, while the X chromosome is similar to the other chromosomes and contains many genes. This being said, Mary Frances Lyon discovered that there
1508-546: A diploid cell with paired chromosomes. Diploid organisms form haploids by dividing, without replicating their DNA, to create daughter cells that randomly inherit one of each pair of chromosomes. Most animals and many plants are diploid for most of their lifespan, with the haploid form reduced to single cell gametes such as sperm or eggs . Although they do not use the haploid/diploid method of sexual reproduction, bacteria have many methods of acquiring new genetic information. Some bacteria can undergo conjugation , transferring
1624-430: A fall from a high place, a cat reflexively twists its body and rights itself to land on its feet using its acute sense of balance and flexibility. This reflex is known as the cat righting reflex . A cat always rights itself in the same way during a fall, if it has enough time to do so, which is the case in falls of 90 cm (3.0 ft) or more. How cats are able to right themselves when falling has been investigated as
1740-495: A fresh kill; some cats reject cold food (which would signal to the cat that the "prey" item is long dead and therefore possibly toxic or decomposing). To aid with navigation and sensation, cats have dozens of movable whiskers (vibrissae) over their body, especially their faces. These provide information on the width of gaps and on the location of objects in the dark, both by touching objects directly and by sensing air currents; they also trigger protective blink reflexes to protect
1856-429: A gene is used to produce a specific amino acid sequence . This process begins with the production of an RNA molecule with a sequence matching the gene's DNA sequence, a process called transcription . This messenger RNA molecule then serves to produce a corresponding amino acid sequence through a process called translation . Each group of three nucleotides in the sequence, called a codon , corresponds either to one of
1972-482: A heritability of only 62%. The molecular basis for genes is deoxyribonucleic acid (DNA). DNA is composed of deoxyribose (sugar molecule), a phosphate group, and a base (amine group). There are four types of bases: adenine (A), cytosine (C), guanine (G), and thymine (T). The phosphates make phosphodiester bonds with the sugars to make long phosphate-sugar backbones. Bases specifically pair together (T&A, C&G) between two backbones and make like rungs on
2088-435: A higher body temperature. In a low-temperature environment, however, the protein's structure is stable and produces dark-hair pigment normally. The protein remains functional in areas of skin that are colder—such as its legs, ears, tail, and face—so the cat has dark hair at its extremities. Environment plays a major role in effects of the human genetic disease phenylketonuria . The mutation that causes phenylketonuria disrupts
2204-506: A ladder. The bases, phosphates, and sugars together make a nucleotide that connects to make long chains of DNA. Genetic information exists in the sequence of these nucleotides, and genes exist as stretches of sequence along the DNA chain. These chains coil into a double a-helix structure and wrap around proteins called Histones which provide the structural support. DNA wrapped around these histones are called chromosomes. Viruses sometimes use
2320-710: A large surface of olfactory mucosa , about 5.8 cm (0.90 in ) in area, which is about twice that of humans. Cats and many other animals have a Jacobson's organ in their mouths that is used in the behavioral process of flehmening . It allows them to sense certain aromas in a way that humans cannot. Cats are sensitive to pheromones such as 3-mercapto-3-methylbutan-1-ol , which they use to communicate through urine spraying and marking with scent glands . Many cats also respond strongly to plants that contain nepetalactone , especially catnip , as they can detect that substance at less than one part per billion. About 70–80% of cats are affected by nepetalactone. This response
2436-505: A living cell or organism may increase or decrease gene transcription. A classic example is two seeds of genetically identical corn, one placed in a temperate climate and one in an arid climate (lacking sufficient waterfall or rain). While the average height the two corn stalks could grow to is genetically determined, the one in the arid climate only grows to half the height of the one in the temperate climate due to lack of water and nutrients in its environment. The word genetics stems from
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#17327834428802552-456: A phenotype involves studying identical and fraternal twins , or other siblings of multiple births . Identical siblings are genetically the same since they come from the same zygote. Meanwhile, fraternal twins are as genetically different from one another as normal siblings. By comparing how often a certain disorder occurs in a pair of identical twins to how often it occurs in a pair of fraternal twins, scientists can determine whether that disorder
2668-403: A series of genes can be combined to form a linear linkage map that roughly describes the arrangement of the genes along the chromosome. Genes express their functional effect through the production of proteins, which are molecules responsible for most functions in the cell. Proteins are made up of one or more polypeptide chains, each composed of a sequence of amino acids . The DNA sequence of
2784-457: A single parent. Offspring that are genetically identical to their parents are called clones . Eukaryotic organisms often use sexual reproduction to generate offspring that contain a mixture of genetic material inherited from two different parents. The process of sexual reproduction alternates between forms that contain single copies of the genome ( haploid ) and double copies ( diploid ). Haploid cells fuse and combine genetic material to create
2900-448: A small circular piece of DNA to another bacterium. Bacteria can also take up raw DNA fragments found in the environment and integrate them into their genomes, a phenomenon known as transformation . These processes result in horizontal gene transfer , transmitting fragments of genetic information between organisms that would be otherwise unrelated. Natural bacterial transformation occurs in many bacterial species, and can be regarded as
3016-400: A smooth blend of traits from their parents. Mendel's work provided examples where traits were definitely not blended after hybridization, showing that traits are produced by combinations of distinct genes rather than a continuous blend. Blending of traits in the progeny is now explained by the action of multiple genes with quantitative effects . Another theory that had some support at that time
3132-616: A strong, flexible body, quick reflexes , and sharp teeth, and its night vision and sense of smell are well developed. It is a social species , but a solitary hunter and a crepuscular predator . Cat communication includes vocalizations—including meowing , purring , trilling, hissing , growling , and grunting —as well as body language . It can hear sounds too faint or too high in frequency for human ears , such as those made by small mammals . It secretes and perceives pheromones . Female domestic cats can have kittens from spring to late autumn in temperate zones and throughout
3248-437: A thicker protective layer of enamel , a less damaging saliva, less retention of food particles between teeth, and a diet mostly devoid of sugar. Nonetheless, they are subject to occasional tooth loss and infection. Cats have protractible and retractable claws. In their normal, relaxed position, the claws are sheathed with the skin and fur around the paw's toe pads. This keeps the claws sharp by preventing wear from contact with
3364-452: A transition of heredity from its status as myth to that of a scientific discipline, by providing a fundamental theoretical basis for genetics in the twentieth century. Other theories of inheritance preceded Mendel's work. A popular theory during the 19th century, and implied by Charles Darwin 's 1859 On the Origin of Species , was blending inheritance : the idea that individuals inherit
3480-412: A unique three-dimensional structure for that protein, and the three-dimensional structures of proteins are related to their functions. Some are simple structural molecules, like the fibers formed by the protein collagen . Proteins can bind to other proteins and simple molecules, sometimes acting as enzymes by facilitating chemical reactions within the bound molecules (without changing the structure of
3596-514: A variable number of caudal vertebrae in the tail (humans have only three to five vestigial caudal vertebrae, fused into an internal coccyx ). The extra lumbar and thoracic vertebrae account for the cat's spinal mobility and flexibility. Attached to the spine are 13 ribs, the shoulder, and the pelvis . Unlike human arms, cat forelimbs are attached to the shoulder by free-floating clavicle bones which allow them to pass their body through any space into which they can fit their head. The cat skull
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3712-400: A variety of hereditary characteristics that replicate and remain active throughout generations. While haploid organisms have only one copy of each chromosome, most animals and many plants are diploid , containing two of each chromosome and thus two copies of every gene. The two alleles for a gene are located on identical loci of the two homologous chromosomes , each allele inherited from
3828-511: Is digitigrade . It walks on the toes, with the bones of the feet making up the lower part of the visible leg. Unlike most mammals, it uses a "pacing" gait and moves both legs on one side of the body before the legs on the other side. It registers directly by placing each hind paw close to the track of the corresponding fore paw, minimizing noise and visible tracks. This also provides sure footing for hind paws when navigating rough terrain. As it speeds up from walking to trotting, its gait changes to
3944-496: Is proximal to the other claws. More proximally is a protrusion which appears to be a sixth "finger". This special feature of the front paws on the inside of the wrists has no function in normal walking but is thought to be an antiskidding device used while jumping. Some cat breeds are prone to having extra digits (" polydactyly "). Polydactylous cats occur along North America's northeast coast and in Great Britain. The cat
4060-488: Is X-chromosome inactivation during reproduction to avoid passing on twice as many genes to the offspring. Lyon's discovery led to the discovery of X-linked diseases. When cells divide, their full genome is copied and each daughter cell inherits one copy. This process, called mitosis , is the simplest form of reproduction and is the basis for asexual reproduction. Asexual reproduction can also occur in multicellular organisms, producing offspring that inherit their genome from
4176-425: Is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell , the organism (e.g. dominance ), and within
4292-571: Is also possible, producing hybrids such as the Kellas cat in Scotland . Development of cat breeds started in the mid 19th century. An analysis of the domestic cat genome revealed that the ancestral wildcat genome was significantly altered in the process of domestication, as specific mutations were selected to develop cat breeds. Most breeds are founded on random-bred domestic cats. Genetic diversity of these breeds varies between regions, and
4408-669: Is also produced by other plants, such as silver vine ( Actinidia polygama ) and the herb valerian ; it may be caused by the smell of these plants mimicking a pheromone and stimulating cats' social or sexual behaviors. Cats have relatively few taste buds compared to humans (470 or so, compared to more than 9,000 on the human tongue). Domestic and wild cats share a taste receptor gene mutation that keeps their sweet taste buds from binding to sugary molecules, leaving them with no ability to taste sweetness . They, however, possess taste bud receptors specialized for acids , amino acids like protein, and bitter tastes. Their taste buds possess
4524-518: Is an important branch in biology because heredity is vital to organisms' evolution . Gregor Mendel , a Moravian Augustinian friar working in the 19th century in Brno , was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today,
4640-459: Is attested from the 16th century and may have been introduced from Dutch poes or from Low German puuskatte , related to Swedish kattepus , or Norwegian pus , pusekatt . Similar forms exist in Lithuanian puižė and Irish puisín or puiscín . The etymology of this word is unknown, but it may have arisen from a sound used to attract a cat. A male cat
4756-400: Is called a tom or tomcat (or a gib , if neutered ). A female is called a queen (or sometimes a molly , if spayed ). A juvenile cat is referred to as a kitten . In Early Modern English , the word kitten was interchangeable with the now-obsolete word catling . A group of cats can be referred to as a clowder , a glaring , or a colony . The scientific name Felis catus
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4872-482: Is caused by genetic or postnatal environmental factors. One famous example involved the study of the Genain quadruplets , who were identical quadruplets all diagnosed with schizophrenia . The genome of a given organism contains thousands of genes, but not all these genes need to be active at any given moment. A gene is expressed when it is being transcribed into mRNA and there exist many cellular methods of controlling
4988-463: Is enhanced by its large movable outer ears, the pinnae , which amplify sounds and help detect the location of a noise. It can detect ultrasound , which enables it to detect ultrasonic calls made by rodent prey. Recent research has shown that cats have socio-spatial cognitive abilities to create mental maps of owners' locations based on hearing owners' voices. Cats have an acute sense of smell, due in part to their well-developed olfactory bulb and
5104-719: Is lowest in purebred populations, which show more than 20 deleterious genetic disorders . The domestic cat has a smaller skull and shorter bones than the European wildcat . It averages about 46 cm (18 in) in head-to-body length and 23–25 cm (9.1–9.8 in) in height, with about 30 cm (12 in) long tails. Males are larger than females. Adult domestic cats typically weigh 4–5 kg (8.8–11.0 lb). Cats have seven cervical vertebrae (as do most mammals ); 13 thoracic vertebrae (humans have 12); seven lumbar vertebrae (humans have five); three sacral vertebrae (as do most mammals, but humans have five); and
5220-413: Is quite flexible and varied but being low-light predators, they are generally crepuscular , which means they tend to be more active near dawn and dusk. However, house cats' behavior is also influenced by human activity and they may adapt to their owners' sleeping patterns to some extent. Genetics Genetics is the study of genes , genetic variation , and heredity in organisms . It
5336-441: Is responsible for the development of structures within multicellular organisms, these patterns arise from the complex interactions between many cells. Within eukaryotes , there exist structural features of chromatin that influence the transcription of genes, often in the form of modifications to DNA and chromatin that are stably inherited by daughter cells. These features are called " epigenetic " because they exist "on top" of
5452-624: Is separately developed in the late-1990s in Australia from European Tiffanie cats by breeding them back to the chinchilla Persian. Therefore, many Australian Tiffanies contain more than three-quarters chinchilla Persian and retain the appearance and temperament of the Old-Fashioned chinchilla Persian. To summarise, the Australian Tiffanie and Tiffanie from the UK are both developed from crossbreeding chinchilla Persians and Burmeses, but
5568-526: Is the only domesticated species of the family Felidae . Advances in archaeology and genetics have shown that the domestication of the cat occurred in the Near East around 7500 BC . It is commonly kept as a pet and farm cat , but also ranges freely as a feral cat avoiding human contact. Valued by humans for companionship and its ability to kill vermin , the cat's retractable claws are adapted to killing small prey like mice and rats . It has
5684-497: Is the physical basis for inheritance: DNA replication duplicates the genetic information by splitting the strands and using each strand as a template for synthesis of a new partner strand. Genes are arranged linearly along long chains of DNA base-pair sequences. In bacteria , each cell usually contains a single circular genophore , while eukaryotic organisms (such as plants and animals) have their DNA arranged in multiple linear chromosomes. These DNA strands are often extremely long;
5800-694: Is the same as that which Mendel published. In his third law, he developed the basic principles of mutation (he can be considered a forerunner of Hugo de Vries ). Festetics argued that changes observed in the generation of farm animals, plants, and humans are the result of scientific laws. Festetics empirically deduced that organisms inherit their characteristics, not acquire them. He recognized recessive traits and inherent variation by postulating that traits of past generations could reappear later, and organisms could produce progeny with different attributes. These observations represent an important prelude to Mendel's theory of particulate inheritance insofar as it features
5916-482: Is unusual among mammals in having very large eye sockets and a powerful specialized jaw. Within the jaw, cats have teeth adapted for killing prey and tearing meat. When it overpowers its prey, a cat delivers a lethal neck bite with its two long canine teeth , inserting them between two of the prey's vertebrae and severing its spinal cord , causing irreversible paralysis and death. Compared to other felines, domestic cats have narrowly spaced canine teeth relative to
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#17327834428806032-715: The Australian National Cats Inc. , ANCATS) uses the name Australian Tiffanie ; however, international acceptance and standardisation did not follow. It is different from the European Tiffanie and the North-American Chantilly-Tiffany . The Tiffanie from the UK is also originating from crossbreeding chinchilla Persian and Burmese cats. However, Australian Tiffanies are essentially longhair Burmillas , as they only come in silver or golden tipped or shaded. The breed
6148-486: The Blue-eyed Mary ( Omphalodes verna ), for example, there exists a gene with alleles that determine the color of flowers: blue or magenta. Another gene, however, controls whether the flowers have color at all or are white. When a plant has two copies of this white allele, its flowers are white—regardless of whether the first gene has blue or magenta alleles. This interaction between genes is called epistasis , with
6264-413: The ancient Greek γενετικός genetikos meaning "genitive"/"generative", which in turn derives from γένεσις genesis meaning "origin". The observation that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding . The modern science of genetics, seeking to understand this process, began with
6380-415: The neutral theory of molecular evolution through publishing the nearly neutral theory of molecular evolution . In this theory, Ohta stressed the importance of natural selection and the environment to the rate at which genetic evolution occurs. One important development was chain-termination DNA sequencing in 1977 by Frederick Sanger . This technology allows scientists to read the nucleotide sequence of
6496-481: The " falling cat problem ". The cat family (Felidae) can pass down many colors and patterns to their offspring. The domestic cat genes MC1R and ASIP allow color variety in their coats. The feline ASIP gene consists of three coding exons. Three novel microsatellite markers linked to ASIP were isolated from a domestic cat BAC clone containing this gene to perform linkage analysis on 89 domestic cats segregated for melanism . The domestic cat family demonstrated
6612-497: The Australian version contains more chinchilla Persian. Consequently, only silver and golden tipped and shaded is allowed in the Australian Tiffanie. The name's use is declining in favour, due to the lax standards for the breed name, the lack of unique identity and the varied genetic makeup. Cat The cat ( Felis catus ), also referred to as domestic cat or house cat , is a small domesticated carnivorous mammal. It
6728-421: The DNA sequence and retain inheritance from one cell generation to the next. Because of epigenetic features, different cell types grown within the same medium can retain very different properties. Although epigenetic features are generally dynamic over the course of development, some, like the phenomenon of paramutation , have multigenerational inheritance and exist as rare exceptions to the general rule of DNA as
6844-632: The F1 offspring mate with each other, the offspring are called the "F2" (second filial) generation. One of the common diagrams used to predict the result of cross-breeding is the Punnett square . When studying human genetic diseases, geneticists often use pedigree charts to represent the inheritance of traits. These charts map the inheritance of a trait in a family tree. Organisms have thousands of genes, and in sexually reproducing organisms these genes generally assort independently of each other. This means that
6960-504: The Greek word genesis —γένεσις, "origin", predates the noun and was first used in a biological sense in 1860. Bateson both acted as a mentor and was aided significantly by the work of other scientists from Newnham College at Cambridge, specifically the work of Becky Saunders , Nora Darwin Barlow , and Muriel Wheldale Onslow . Bateson popularized the usage of the word genetics to describe
7076-448: The ability of the body to break down the amino acid phenylalanine , causing a toxic build-up of an intermediate molecule that, in turn, causes severe symptoms of progressive intellectual disability and seizures. However, if someone with the phenylketonuria mutation follows a strict diet that avoids this amino acid, they remain normal and healthy. A common method for determining how genes and environment ("nature and nurture") contribute to
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#17327834428807192-444: The adaptive function of repair of DNA damages. The first cytological demonstration of crossing over was performed by Harriet Creighton and Barbara McClintock in 1931. Their research and experiments on corn provided cytological evidence for the genetic theory that linked genes on paired chromosomes do in fact exchange places from one homolog to the other. The probability of chromosomal crossover occurring between two given points on
7308-440: The basis for inheritance. During the process of DNA replication, errors occasionally occur in the polymerization of the second strand. These errors, called mutations, can affect the phenotype of an organism, especially if they occur within the protein coding sequence of a gene. Error rates are usually very low—1 error in every 10–100 million bases—due to the "proofreading" ability of DNA polymerases . Processes that increase
7424-700: The beginning of the 1st century AD. By the end of the Western Roman Empire in the 5th century, the Egyptian domestic cat lineage had arrived in a Baltic Sea port in northern Germany . The leopard cat ( Prionailurus bengalensis ) was tamed independently in China around 5500 BC. This line of partially domesticated cats leaves no trace in the domestic cat populations of today. During domestication, cats have undergone only minor changes in anatomy and behavior, and they are still capable of surviving in
7540-479: The breed, it is officially registered under the name Tiffanie or within the Asian Group as Tiffanie or Asian Longhair . In some registries the colouration is restricted to silver or golden tipped or shaded , and the breed is registered as Burmilla Longhair or Australian Tiffanie . Among the cat fancy the breed is also known as the Asian Semi-longhair . The Tiffanie is often confused with
7656-624: The cat and other wild mammals to the island from the Middle Eastern mainland. Scientists therefore assume that African wildcats were attracted to early human settlements in the Fertile Crescent by rodents, in particular the house mouse ( Mus musculus ), and were tamed by Neolithic farmers. This mutual relationship between early farmers and tamed cats lasted thousands of years. As agricultural practices spread, so did tame and domesticated cats. Wildcats of Egypt contributed to
7772-404: The cat plays the role of the environment. The cat's genes code for dark hair, thus the hair-producing cells in the cat make cellular proteins resulting in dark hair. But these dark hair-producing proteins are sensitive to temperature (i.e. have a mutation causing temperature-sensitivity) and denature in higher-temperature environments, failing to produce dark-hair pigment in areas where the cat has
7888-429: The cell, these genes for tryptophan synthesis are no longer needed. The presence of tryptophan directly affects the activity of the genes—tryptophan molecules bind to the tryptophan repressor (a transcription factor), changing the repressor's structure such that the repressor binds to the genes. The tryptophan repressor blocks the transcription and expression of the genes, thereby creating negative feedback regulation of
8004-421: The chromosome is related to the distance between the points. For an arbitrarily long distance, the probability of crossover is high enough that the inheritance of the genes is effectively uncorrelated. For genes that are closer together, however, the lower probability of crossover means that the genes demonstrate genetic linkage; alleles for the two genes tend to be inherited together. The amounts of linkage between
8120-422: The combined DNA sequences of all chromosomes) is called the genome . DNA is most often found in the nucleus of cells, but Ruth Sager helped in the discovery of nonchromosomal genes found outside of the nucleus. In plants, these are often found in the chloroplasts and in other organisms, in the mitochondria. These nonchromosomal genes can still be passed on by either partner in sexual reproduction and they control
8236-486: The context of a population. Genetics has given rise to a number of subfields, including molecular genetics , epigenetics , and population genetics . Organisms studied within the broad field span the domains of life ( archaea , bacteria , and eukarya ). Genetic processes work in combination with an organism's environment and experiences to influence development and behavior , often referred to as nature versus nurture . The intracellular or extracellular environment of
8352-417: The expression of genes such that proteins are produced only when needed by the cell. Transcription factors are regulatory proteins that bind to DNA, either promoting or inhibiting the transcription of a gene. Within the genome of Escherichia coli bacteria, for example, there exists a series of genes necessary for the synthesis of the amino acid tryptophan . However, when tryptophan is already available to
8468-511: The extinction of bird , mammal , and reptile species. As of 2017, the domestic cat was the second most popular pet in the United States, with 95.6 million cats owned and around 42 million households owning at least one cat. In the United Kingdom, 26% of adults have a cat, with an estimated population of 10.9 million pet cats as of 2020. As of 2021, there were an estimated 220 million owned and 480 million stray cats in
8584-407: The eyes from damage. Outdoor cats are active both day and night, although they tend to be slightly more active at night. Domestic cats spend the majority of their time in the vicinity of their homes but can range many hundreds of meters from this central point. They establish territories that vary considerably in size, in one study ranging 7–28 ha (17–69 acres). The timing of cats' activity
8700-483: The ground and allows for the silent stalking of prey. The claws on the forefeet are typically sharper than those on the hindfeet. Cats can voluntarily extend their claws on one or more paws. They may extend their claws in hunting or self-defense, climbing, kneading , or for extra traction on soft surfaces. Cats shed the outside layer of their claw sheaths when scratching rough surfaces. Most cats have five claws on their front paws and four on their rear paws. The dewclaw
8816-411: The high IMP and free l-Histidine contents of tuna, which produces a strong umami taste synergy that is highly preferred by cats". One of the researchers in this research has stated, "I think umami is as important for cats as sweet is for humans". Cats also have a distinct temperature preference for their food, preferring food with a temperature around 38 °C (100 °F) which is similar to that of
8932-469: The information an organism uses to function, the environment plays an important role in determining the ultimate phenotypes an organism displays. The phrase " nature and nurture " refers to this complementary relationship. The phenotype of an organism depends on the interaction of genes and the environment. An interesting example is the coat coloration of the Siamese cat . In this case, the body temperature of
9048-406: The inheritance of an allele for yellow or green pea color is unrelated to the inheritance of alleles for white or purple flowers. This phenomenon, known as " Mendel's second law " or the "law of independent assortment," means that the alleles of different genes get shuffled between parents to form offspring with many different combinations. Different genes often interact to influence the same trait. In
9164-427: The largest human chromosome, for example, is about 247 million base pairs in length. The DNA of a chromosome is associated with structural proteins that organize, compact, and control access to the DNA, forming a material called chromatin ; in eukaryotes, chromatin is usually composed of nucleosomes , segments of DNA wound around cores of histone proteins. The full set of hereditary material in an organism (usually
9280-634: The maternal gene pool of the domestic cat at a later time. The earliest known evidence for the occurrence of the domestic cat in Greece dates to around 1200 BC. Greek, Phoenician , Carthaginian and Etruscan traders introduced domestic cats to southern Europe. By the 5th century BC, they were familiar animals around settlements in Magna Graecia and Etruria . During the Roman Empire , they were introduced to Corsica and Sardinia before
9396-602: The modern domesticated subspecies F. silvestris catus sampled worldwide was considered to have likely descended from the African wildcat ( F. lybica ), following results of phylogenetic research. In 2017, the IUCN Cat Classification Taskforce followed the recommendation of the ICZN in regarding the domestic cat as a distinct species, Felis catus . The domestic cat is a member of the Felidae,
9512-571: The nature of inheritance in plants. In his paper " Versuche über Pflanzenhybriden " (" Experiments on Plant Hybridization "), presented in 1865 to the Naturforschender Verein (Society for Research in Nature) in Brno , Mendel traced the inheritance patterns of certain traits in pea plants and described them mathematically. Although this pattern of inheritance could only be observed for a few traits, Mendel's work suggested that heredity
9628-525: The now extinct and unrelated Chantilly-Tiffany , or Foreign Longhair, a longhaired North American breed originating from chocolate-brown cats of unknown origin. Similarly, the Tiffany in the NZCF (New Zealand) refers to a Burmese longhair . The Tiffanie was developed in the 1980s in the United Kingdom as a longhaired version of the Asian Shorthair. The breed origins can be traced back to matings between
9744-500: The offspring of a mating pair. Genes on the same chromosome would theoretically never recombine. However, they do, via the cellular process of chromosomal crossover . During crossover, chromosomes exchange stretches of DNA, effectively shuffling the gene alleles between the chromosomes. This process of chromosomal crossover generally occurs during meiosis , a series of cell divisions that creates haploid cells. Meiotic recombination , particularly in microbial eukaryotes , appears to serve
9860-435: The original sequence. A particularly important source of DNA damages appears to be reactive oxygen species produced by cellular aerobic respiration , and these can lead to mutations. In organisms that use chromosomal crossover to exchange DNA and recombine genes, errors in alignment during meiosis can also cause mutations. Errors in crossover are especially likely when similar sequences cause partner chromosomes to adopt
9976-470: The phenotype of the organism, while the other allele is called recessive as its qualities recede and are not observed. Some alleles do not have complete dominance and instead have incomplete dominance by expressing an intermediate phenotype, or codominance by expressing both alleles at once. When a pair of organisms reproduce sexually , their offspring randomly inherit one of the two alleles from each parent. These observations of discrete inheritance and
10092-543: The process of protein production . It was discovered that the cell uses DNA as a template to create matching messenger RNA , molecules with nucleotides very similar to DNA. The nucleotide sequence of a messenger RNA is used to create an amino acid sequence in protein; this translation between nucleotide sequences and amino acid sequences is known as the genetic code . With the newfound molecular understanding of inheritance came an explosion of research. A notable theory arose from Tomoko Ohta in 1973 with her amendment to
10208-435: The product rule, the sum rule, and more. Geneticists use diagrams and symbols to describe inheritance. A gene is represented by one or a few letters. Often a "+" symbol is used to mark the usual, non-mutant allele for a gene. In fertilization and breeding experiments (and especially when discussing Mendel's laws) the parents are referred to as the "P" generation and the offspring as the "F1" (first filial) generation. When
10324-519: The properties of a protein by destabilizing the structure or changing the surface of the protein in a way that changes its interaction with other proteins and molecules. For example, sickle-cell anemia is a human genetic disease that results from a single base difference within the coding region for the β-globin section of hemoglobin, causing a single amino acid change that changes hemoglobin's physical properties. Sickle-cell versions of hemoglobin stick to themselves, stacking to form fibers that distort
10440-426: The protein itself). Protein structure is dynamic; the protein hemoglobin bends into slightly different forms as it facilitates the capture, transport, and release of oxygen molecules within mammalian blood. A single nucleotide difference within DNA can cause a change in the amino acid sequence of a protein. Because protein structures are the result of their amino acid sequences, some changes can dramatically change
10556-406: The rate of changes in DNA are called mutagenic : mutagenic chemicals promote errors in DNA replication, often by interfering with the structure of base-pairing, while UV radiation induces mutations by causing damage to the DNA structure. Chemical damage to DNA occurs naturally as well and cells use DNA repair mechanisms to repair mismatches and breaks. The repair does not, however, always restore
10672-487: The receptors needed to detect umami . However, these receptors contain molecular changes that make cat taste umami different from that of humans. In humans, they detect the amino acids glutamic acid and aspartic acid , but in cats, they instead detect inosine monophosphate and l-Histidine . These molecules are particularly enriched in tuna . This, it has been argued, is why cats find tuna so palatable : as put by researchers into cat taste, "the specific combination of
10788-408: The same allele of a given gene are called homozygous at that gene locus , while organisms with two different alleles of a given gene are called heterozygous . The set of alleles for a given organism is called its genotype , while the observable traits of the organism are called its phenotype . When organisms are heterozygous at a gene, often one allele is called dominant as its qualities dominate
10904-401: The second gene epistatic to the first. Many traits are not discrete features (e.g. purple or white flowers) but are instead continuous features (e.g. human height and skin color ). These complex traits are products of many genes. The influence of these genes is mediated, to varying degrees, by the environment an organism has experienced. The degree to which an organism's genes contribute to
11020-509: The segregation of alleles are collectively known as Mendel's first law or the Law of Segregation. However, the probability of getting one gene over the other can change due to dominant, recessive, homozygous, or heterozygous genes. For example, Mendel found that if you cross heterozygous organisms your odds of getting the dominant trait is 3:1. Real geneticist study and calculate probabilities by using theoretical probabilities, empirical probabilities,
11136-653: The shape of red blood cells carrying the protein. These sickle-shaped cells no longer flow smoothly through blood vessels , having a tendency to clog or degrade, causing the medical problems associated with this disease. Some DNA sequences are transcribed into RNA but are not translated into protein products—such RNA molecules are called non-coding RNA . In some cases, these products fold into structures which are involved in critical cell functions (e.g. ribosomal RNA and transfer RNA ). RNA can also have regulatory effects through hybridization interactions with other RNA molecules (such as microRNA ). Although genes contain all
11252-446: The similar molecule RNA instead of DNA as their genetic material. DNA normally exists as a double-stranded molecule, coiled into the shape of a double helix . Each nucleotide in DNA preferentially pairs with its partner nucleotide on the opposite strand: A pairs with T, and C pairs with G. Thus, in its two-stranded form, each strand effectively contains all necessary information, redundant with its partner strand. This structure of DNA
11368-500: The single celled alga Acetabularia . The Hershey–Chase experiment in 1952 confirmed that DNA (rather than protein) is the genetic material of the viruses that infect bacteria, providing further evidence that DNA is the molecule responsible for inheritance. James Watson and Francis Crick determined the structure of DNA in 1953, using the X-ray crystallography work of Rosalind Franklin and Maurice Wilkins that indicated DNA has
11484-518: The size of their jaw, which is an adaptation to their preferred prey of small rodents, which have small vertebrae. The premolar and first molar together compose the carnassial pair on each side of the mouth, which efficiently shears meat into small pieces, like a pair of scissors. These are vital in feeding, since cats' small molars cannot chew food effectively, and cats are largely incapable of mastication. Cats tend to have better teeth than most humans, with decay generally less likely because of
11600-441: The strands are separated, new partner strands can be reconstructed for each based on the sequence of the old strand. This property is what gives DNA its semi-conservative nature where one strand of new DNA is from an original parent strand. Although the structure of DNA showed how inheritance works, it was still not known how DNA influences the behavior of cells. In the following years, scientists tried to understand how DNA controls
11716-580: The study of inheritance in his inaugural address to the Third International Conference on Plant Hybridization in London in 1906. After the rediscovery of Mendel's work, scientists tried to determine which molecules in the cell were responsible for inheritance. In 1900, Nettie Stevens began studying the mealworm. Over the next 11 years, she discovered that females only had the X chromosome and males had both X and Y chromosomes. She
11832-536: The tryptophan synthesis process. Differences in gene expression are especially clear within multicellular organisms , where cells all contain the same genome but have very different structures and behaviors due to the expression of different sets of genes. All the cells in a multicellular organism derive from a single cell, differentiating into variant cell types in response to external and intercellular signals and gradually establishing different patterns of gene expression to create different behaviors. As no single gene
11948-482: The twenty possible amino acids in a protein or an instruction to end the amino acid sequence ; this correspondence is called the genetic code . The flow of information is unidirectional: information is transferred from nucleotide sequences into the amino acid sequence of proteins, but it never transfers from protein back into the sequence of DNA—a phenomenon Francis Crick called the central dogma of molecular biology . The specific sequence of amino acids results in
12064-545: The two is responsible for inheritance. In 1928 , Frederick Griffith discovered the phenomenon of transformation : dead bacteria could transfer genetic material to "transform" other still-living bacteria. Sixteen years later, in 1944, the Avery–MacLeod–McCarty experiment identified DNA as the molecule responsible for transformation. The role of the nucleus as the repository of genetic information in eukaryotes had been established by Hämmerling in 1943 in his work on
12180-862: The wild members of this genus evolved through sympatric or parapatric speciation , whereas the domestic cat evolved through artificial selection . The domestic cat and its closest wild ancestor are diploid and both possess 38 chromosomes and roughly 20,000 genes. Pantherinae other Felinae lineages Jungle cat ( F. chaus ) [REDACTED] Black-footed cat ( F. nigripes ) Sand cat ( F. margarita ) Chinese mountain cat ( F. bieti ) African wildcat ( F. lybica ) European wildcat ( F. silvestris ) [REDACTED] Domestic cat [REDACTED] Sand cat ( F. margarita ) Chinese mountain cat ( F. bieti ) European wildcat ( F. silvestris ) [REDACTED] Southern African wildcat (F. l. cafra) Asiatic wildcat (F. l. ornata) Near Eastern wildcat Domestic cat [REDACTED] It
12296-625: The wild. Several natural behaviors and characteristics of wildcats may have pre-adapted them for domestication as pets. These traits include their small size, social nature, obvious body language, love of play, and high intelligence. Since they practice rigorous grooming habits and have an instinctual drive to bury and hide their urine and feces, they are generally much less messy than other domesticated animals. Captive Leopardus cats may also display affectionate behavior toward humans but were not domesticated. House cats often mate with feral cats. Hybridization between domestic and other Felinae species
12412-538: The work of the Augustinian friar Gregor Mendel in the mid-19th century. Prior to Mendel, Imre Festetics , a Hungarian noble, who lived in Kőszeg before Mendel, was the first who used the word "genetic" in hereditarian context, and is considered the first geneticist. He described several rules of biological inheritance in his work The genetic laws of nature (Die genetischen Gesetze der Natur, 1819). His second law
12528-548: The world. The origin of the English word cat , Old English catt , is thought to be the Late Latin word cattus , which was first used at the beginning of the 6th century. The Late Latin word may be derived from an unidentified African language . The Nubian word kaddîska 'wildcat' and Nobiin kadīs are possible sources or cognates. The forms might also have derived from an ancient Germanic word that
12644-403: The year in equatorial regions , with litter sizes often ranging from two to five kittens. Domestic cats are bred and shown at events as registered pedigreed cats , a hobby known as cat fancy . Animal population control of cats may be achieved by spaying and neutering , but their proliferation and the abandonment of pets has resulted in large numbers of feral cats worldwide, contributing to
12760-518: Was able to conclude that sex is a chromosomal factor and is determined by the male. In 1911, Thomas Hunt Morgan argued that genes are on chromosomes , based on observations of a sex-linked white eye mutation in fruit flies . In 1913, his student Alfred Sturtevant used the phenomenon of genetic linkage to show that genes are arranged linearly on the chromosome. Although genes were known to exist on chromosomes, chromosomes are composed of both protein and DNA, and scientists did not know which of
12876-412: Was absorbed into Latin and then into Greek, Syriac, and Arabic. The word may be derived from Germanic and Northern European languages, and ultimately be borrowed from Uralic , cf. Northern Sámi gáđfi , 'female stoat ', and Hungarian hölgy , 'lady, female stoat'; from Proto-Uralic * käďwä , 'female (of a furred animal)'. The English puss , extended as pussy and pussycat ,
12992-591: Was first observed by Gregor Mendel, who studied the segregation of heritable traits in pea plants, showing for example that flowers on a single plant were either purple or white—but never an intermediate between the two colors. The discrete versions of the same gene controlling the inherited appearance (phenotypes) are called alleles . In the case of the pea, which is a diploid species, each individual plant has two copies of each gene, one copy inherited from each parent. Many species, including humans, have this pattern of inheritance. Diploid organisms with two copies of
13108-519: Was long thought that the domestication of the cat began in ancient Egypt , where cats were venerated from around 3100 BC. However, the earliest known indication for the taming of an African wildcat was excavated close by a human Neolithic grave in Shillourokambos , southern Cyprus , dating to about 7500–7200 BC. Since there is no evidence of native mammalian fauna on Cyprus, the inhabitants of this Neolithic village most likely brought
13224-421: Was particulate, not acquired, and that the inheritance patterns of many traits could be explained through simple rules and ratios. The importance of Mendel's work did not gain wide understanding until 1900, after his death, when Hugo de Vries and other scientists rediscovered his research. William Bateson , a proponent of Mendel's work, coined the word genetics in 1905. The adjective genetic , derived from
13340-631: Was proposed by Carl Linnaeus in 1758 for a domestic cat. Felis catus domesticus was proposed by Johann Christian Polycarp Erxleben in 1777. Felis daemon proposed by Konstantin Satunin in 1904 was a black cat from the Transcaucasus , later identified as a domestic cat. In 2003, the International Commission on Zoological Nomenclature ruled that the domestic cat is a distinct species, namely Felis catus . In 2007,
13456-529: Was the inheritance of acquired characteristics : the belief that individuals inherit traits strengthened by their parents. This theory (commonly associated with Jean-Baptiste Lamarck ) is now known to be wrong—the experiences of individuals do not affect the genes they pass to their children. Other theories included Darwin's pangenesis (which had both acquired and inherited aspects) and Francis Galton 's reformulation of pangenesis as both particulate and inherited. Modern genetics started with Mendel's studies of
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