80-536: The Burmah Oil Company was a leading British oil company which was once a constituent of the FTSE 100 Index . In 1966, Castrol was acquired by Burmah, which was renamed Burmah-Castrol . BP Amoco purchased the company in 2000. The company was founded in Glasgow in 1886 by David Sime Cargill , an East India merchant, to succeed his Rangoon Oil Company Ltd, also of Glasgow, to further expand and develop oil fields in
160-435: A biochemical target, compounds described in patents or literature, or biocontrol organisms. Compounds that are active in the screening process, known as hits or leads, cannot be used as pesticides, except for biocontrol organisms and some potent natural products. These lead compounds need to be optimised by a series of cycles of synthesis and testing of analogs. For approval by regulatory authorities for use as pesticides,
240-548: A drilling/production oil-platform in 20 ft (6.1 m) of water some 18 miles off Vermilion Parish, Louisiana . Kerr-McGee Oil Industries, as operator for partners Phillips Petroleum ( ConocoPhillips ) and Stanolind Oil & Gas ( BP ), completed its historic Ship Shoal Block 32 well in November 1947, months before Superior actually drilled a discovery from their Vermilion platform farther offshore. In any case, that made Kerr-McGee's Gulf of Mexico well, Kermac No. 16,
320-515: A lighting and heating fuel, the demand for petroleum increased greatly, and by the early twentieth century had become the most valuable commodity traded on world markets. Imperial Russia produced 3,500 tons of oil in 1825 and doubled its output by mid-century. After oil drilling began in the region of present-day Azerbaijan in 1846, in Baku , the Russian Empire built two large pipelines:
400-557: A market share. For example: Midstream operations are sometimes classified within the downstream sector, but these operations compose a separate and discrete sector of the petroleum industry. Midstream operations and processes include the following: While some upstream companies carry out certain midstream operations, the midstream sector is dominated by a number of companies that specialize in these services. Midstream companies include: The oil and gas industry spends only 0.4% of its net sales on research & development (R&D) which
480-538: A pesticide is a chemical or biological agent (such as a virus , bacterium , or fungus ) that deters, incapacitates, kills, or otherwise discourages pests. Target pests can include insects, plant pathogens , weeds, molluscs , birds , mammals , fish , nematodes (roundworms), and microbes that destroy property, cause nuisance, or spread disease, or are disease vectors . Along with these benefits, pesticides also have drawbacks, such as potential toxicity to humans and other species. The word pesticide derives from
560-401: A pesticide was first seen in the 1920s with inorganic pesticides, and later it was found that development of resistance is to be expected, and measures to delay it are important. Integrated pest management (IPM) was introduced in the 1950s. By careful analysis and spraying only when an economical or biological threshold of crop damage is reached, pesticide application is reduced. This became in
640-455: Is becoming widespread and has been used with success in countries such as Indonesia , China , Bangladesh , the U.S., Australia , and Mexico . IPM attempts to recognize the more widespread impacts of an action on an ecosystem , so that natural balances are not upset. Each use of a pesticide carries some associated risk. Proper pesticide use decreases these associated risks to a level deemed acceptable by pesticide regulatory agencies such as
720-652: Is generally accepted that oil is formed mostly from the carbon rich remains of ancient plankton after exposure to heat and pressure in Earth 's crust over hundreds of millions of years. Over time, the decayed residue was covered by layers of mud and silt, sinking further down into Earth's crust and preserved there between hot and pressured layers, gradually transforming into oil reservoirs . Petroleum in an unrefined state has been utilized by humans for over 5000 years. Oil in general has been used since early human history to keep fires ablaze and in warfare . Its importance to
800-521: Is in comparison with a range of other industries the lowest share. Governments such as the United States government provide a heavy public subsidy to petroleum companies , with major tax breaks at various stages of oil exploration and extraction, including the costs of oil field leases and drilling equipment. In recent years, enhanced oil recovery techniques – most notably multi-stage drilling and hydraulic fracturing ("fracking") – have moved to
880-597: Is often employed by means of aerobic degradation. More recently, other bioremediative methods have been explored such as phytoremediation and thermal remediation. The industry is the largest industrial source of emissions of volatile organic compounds (VOCs), a group of chemicals that contribute to the formation of ground-level ozone ( smog ). The combustion of fossil fuels produces greenhouse gases and other air pollutants as by-products. Pollutants include nitrogen oxides , sulphur dioxide , volatile organic compounds and heavy metals . Researchers have discovered that
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#1732765817808960-456: Is similarly challenging, yet well documented in developing countries. Because of critical development periods of the fetus and newborn children, these non-working populations are more vulnerable to the effects of pesticides, and may be at increased risk of developing neurocognitive effects and impaired development. While measuring biomarkers or markers of biological effects may provide more accurate estimates of exposure, collecting these data in
1040-474: Is substantial evidence of associations between organophosphate insecticide exposures and neurobehavioral alterations. Limited evidence also exists for other negative outcomes from pesticide exposure including neurological, birth defects , and fetal death . The American Academy of Pediatrics recommends limiting exposure of children to pesticides and using safer alternatives: Pesticides are also found in majority of U.S. households with 88 million out of
1120-504: Is to find new compounds or agents with improved properties such as a new mode of action or lower application rate. Another aim is to replace older pesticides which have been banned for reasons of toxicity or environmental harm or have become less effective due to development of resistance . The process starts with testing (screening) against target organisms such as insects , fungi or plants . Inputs are typically random compounds, natural products , compounds designed to disrupt
1200-638: Is vital to many industries, and is necessary for the maintenance of industrial civilization in its current configuration, making it a critical concern for many nations. Oil accounts for a large percentage of the world's energy consumption , ranging from a low of 32% for Europe and Asia, to a high of 53% for the Middle East. Other geographic regions' consumption patterns are as follows: South and Central America (44%), Africa (41%), and North America (40%). The world consumes 36 billion barrels (5.8 km ) of oil per year, with developed nations being
1280-483: Is widespread in Latin America , as around US$ 3 billion are spent each year in the region. Records indicate an increase in the frequency of pesticide poisonings over the past two decades. The most common incidents of pesticide poisoning is thought to result from exposure to organophosphate and carbamate insecticides. At-home pesticide use, use of unregulated products, and the role of undocumented workers within
1360-710: The BOC brand in Burma , Bangladesh (formerly East Pakistan ) and Assam (in India ), and through a joint venture Burmah-Shell with Shell in the rest of India. Until 1901, when the Standard Oil Company started operations in Burma , Burmah Oil enjoyed a monopoly in the region. The company operated in Burma until 1963, when Ne Win nationalized all industries in the country. Out of the nationalized assets of Burmah Oil,
1440-537: The Indian subcontinent . On his death in 1904, the ownership and chairmanship passed to his son John Cargill . In the 1900s, the Admiralty was planning a changeover from coal to fuel oil for powering the engines of its warships. In 1905, Burmah signed a contract with the Admiralty to supply naval fuel oil from Rangoon. In the first decade of the 20th century, Burmah Oil founded Anglo-Persian Oil Company to succeed
1520-581: The Myanma Oil and Gas Enterprise was created. The company was involved in a landmark legal case in 1964, Burmah Oil Co. v Lord Advocate , concerning compensation for the destruction of oil fields in Burma by British forces in 1942 to avoid them falling into the hands of the invading Japanese army, winning a 3-2 decision in the Judicial Committee of the House of Lords , but the effect of this
1600-598: The UN Environment Programme estimate that 3 million agricultural workers in the developing world experience severe poisoning from pesticides each year, resulting in 18,000 deaths. According to one study, as many as 25 million workers in developing countries may suffer mild pesticide poisoning yearly. Other occupational exposures besides agricultural workers, including pet groomers, groundskeepers , and fumigators , may also put individuals at risk of health effects from pesticides. Pesticide use
1680-624: The United States Environmental Protection Agency (EPA) and the Pest Management Regulatory Agency (PMRA) of Canada. DDT , sprayed on the walls of houses, is an organochlorine that has been used to fight malaria vectors (mosquitos) since the 1940s. The World Health Organization recommend this approach. It and other organochlorine pesticides have been banned in most countries worldwide because of their persistence in
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#17327658178081760-434: The environment or the food chain in order to be approved by the authorities. Persistent pesticides, including DDT , were banned many years ago , an exception being spraying in houses to combat malaria vectors . From biblical times until the 1950s the pesticides used were inorganic compounds and plant extracts . The inorganic compounds were derivatives of copper , arsenic , mercury, sulfur , among others, and
1840-582: The petrochemical industry can produce ground-level ozone pollution at higher amounts in winter than in summer. Greenhouse gases caused by burning fossil fuels drive climate change . In 1959, at a symposium organised by the American Petroleum Institute for the centennial of the American oil industry , the physicist Edward Teller warned of the danger of global climate change . Edward Teller explained that carbon dioxide "in
1920-499: The phloem or both. Non-systemic pesticides (contact pesticides) remain on the surface and act through direct contact with the target organism. Pesticides are more effective if they are systemic. Systemicity is a prerequisite for the pesticide to be used as a seed-treatment. Pesticides can be classified as persistent (non-biodegradable) or non-persistent ( biodegradable ). A pesticide must be persistent enough to kill or control its target but must degrade fast enough not to accumulate in
2000-512: The world economy however, evolved slowly, with whale oil being used for lighting in the 19th century and wood and coal used for heating and cooking well into the 20th century. Even though the Industrial Revolution generated an increasing need for energy, this was initially met mainly by coal, and from other sources including whale oil. However, when it was discovered that kerosene could be extracted from crude oil and used as
2080-470: The 121.1 million households indicating that they use some form of pesticide in 2012. As of 2007, there were more than 1,055 active ingredients registered as pesticides, which yield over 20,000 pesticide products that are marketed in the United States. Owing to inadequate regulation and safety precautions, 99% of pesticide-related deaths occur in developing countries that account for only 25% of pesticide usage. One study found pesticide self-poisoning
2160-590: The 1880s. In the early 1930s the Texas Company developed the first mobile steel barges for drilling in the brackish coastal areas of the Gulf of Mexico . In 1937 Pure Oil Company (now part of Chevron Corporation ) and its partner Superior Oil Company (now part of ExxonMobil Corporation ) used a fixed platform to develop a field in 14 feet (4.3 m) of water, one mile (1.6 km) offshore of Calcasieu Parish, Louisiana . In early 1947 Superior Oil erected
2240-538: The 2000s and less than 40 in the 2010s. Biopesticides are cheaper to develop, since the authorities require less toxicological and environmental study. Since 2000 the rate of new biological product introduction has frequently exceeded that of conventional products. More than 25% of existing chemical pesticides contain one or more chiral centres (stereogenic centres). Newer pesticides with lower application rates tend to have more complex structures, and thus more often contain chiral centres. In cases when most or all of
2320-456: The 2020s the official policy of international organisations, industry, and many governments. With the introduction of high yielding varieties in the 1960s in the green revolution , more pesticides were used. Since the 1980s genetically modified crops were introduced, which resulted in lower amounts of insecticides used on them. Organic agriculture, which uses only non-synthetic pesticides, has grown and in 2020 represents about 1.5 per cent of
2400-625: The 833 km long pipeline to transport oil from the Caspian to the Black Sea port of Batum (Baku-Batum pipeline), completed in 1906, and the 162 km long pipeline to carry oil from Chechnya to the Caspian. The first drilled oil wells in Baku were built in 1871–1872 by Ivan Mirzoev , an Armenian businessman who is referred to as one of the 'founding fathers' of Baku's oil industry. At
2480-586: The East Indies oil-supply (especially via submarine campaigns ) considerably weakened Japan in the latter part of the war. After World War II ended in 1945, the countries of the Middle East took the lead in oil production from the United States. Important developments since World War II include deep-water drilling, the introduction of the drillship , and the growth of a global shipping network for petroleum – relying upon oil tankers and pipelines. In 1949
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2560-619: The Latin pestis (plague) and caedere (kill). The Food and Agriculture Organization (FAO) has defined pesticide as: Pesticides can be classified by target organism (e.g., herbicides , insecticides , fungicides , rodenticides , and pediculicides – see table), Biopesticides according to the EPA include microbial pesticides, biochemical pesticides, and plant-incorporated protectants. Pesticides can be classified into structural classes, with many structural classes developed for each of
2640-779: The Middle East. The expansion of Imperial Japan to the south aimed largely at accessing the oil-fields of the Dutch East Indies. Germany, cut off from sea-borne oil supplies by Allied blockade , failed in Operation Edelweiss to secure the Caucasus oil-fields for the Axis military in 1942, while Romania deprived the Wehrmacht of access to Ploesti oilfields – the largest in Europe – from August 1944. Cutting off
2720-703: The USA (457 kt) was the second-largest user. Applications per cropland area in 2021 varied widely, from 10.9 kg/ hectare in Brazil to 0.8 kg/ha in the Russian Federation. The level in Brazil was about twice as high as in Argentina (5.6 kg/ha) and Indonesia (5.3 kg/ha). Insecticide use in the US has declined by more than half since 1980 (0.6%/yr), mostly due to the near phase-out of organophosphates . In corn fields,
2800-595: The Workplace". Better understanding of how pesticides elicit their toxic effects is needed before this method of exposure assessment can be applied to occupational exposure of agricultural workers. Alternative methods to assess exposure include questionnaires to discern from participants whether they are experiencing symptoms associated with pesticide poisoning. Self-reported symptoms may include headaches, dizziness, nausea, joint pain, or respiratory symptoms. Multiple challenges exist in assessing exposure to pesticides in
2880-764: The advent of hydraulic fracturing and other horizontal drilling techniques, shale play has seen an enormous uptick in production. Areas of shale such as the Permian Basin and Eagle-Ford have become huge hotbeds of production for the largest oil corporations in the United States. The American Petroleum Institute divides the petroleum industry into five sectors: Oil companies used to be classified by sales as " supermajors " ( BP , Chevron , ExxonMobil , ConocoPhillips , Shell , Eni and TotalEnergies ), "majors", and "independents" or "jobbers". In recent years however, National Oil Companies (NOC, as opposed to IOC, International Oil Companies) have come to control
2960-572: The agricultural industry makes characterizing true pesticide exposure a challenge. It is estimated that 50–80% of pesticide poisoning cases are unreported. Underreporting of pesticide poisoning is especially common in areas where agricultural workers are less likely to seek care from a healthcare facility that may be monitoring or tracking the incidence of acute poisoning. The extent of unintentional pesticide poisoning may be much greater than available data suggest, particularly among developing countries. Globally, agriculture and food production remain one of
3040-527: The area. Canada's first gusher (flowing well) erupted on January 16, 1862, when local oil-man John Shaw struck oil at 158 feet (48 m). For a week the oil gushed unchecked at levels reported as high as 3,000 barrels per day. The first modern oil-drilling in the United States began in West Virginia and Pennsylvania in the 1850s. Edwin Drake 's 1859 well near Titusville, Pennsylvania , typically considered
3120-628: The atmosphere causes a greenhouse effect " and that burning more fossil fuels could "melt the icecaps and submerge New York". The Intergovernmental Panel on Climate Change , founded by the United Nations in 1988, concludes that human-sourced greenhouse gases are responsible for most of the observed temperature increase since the middle of the twentieth century. As a result of climate change concerns, many people have begun using other methods of energy such as solar and wind. This recent shift has some petroleum enthusiasts skeptical about
3200-632: The breakdown of acetylcholine at the neural synapse . Excess acetylcholine can lead to symptoms like muscle cramps or tremors, confusion, dizziness and nausea. Studies show that farm workers in Ethiopia, Kenya, and Zimbabwe have decreased concentrations of plasma acetylcholinesterase, the enzyme responsible for breaking down acetylcholine acting on synapses throughout the nervous system . Other studies in Ethiopia have observed reduced respiratory function among farm workers who spray crops with pesticides. Numerous exposure pathways for farm workers increase
3280-403: The compound is metabolized and eliminated from the body, and provide insights into the timing of exposure. Markers of biological effect provide an estimation of exposure based on cellular activities related to the mechanism of action. For example, many studies investigating exposure to pesticides often involve the quantification of the acetylcholinesterase enzyme at the neural synapse to determine
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3360-746: The cost side of pesticide use there can be costs to the environment and costs to human health. Pesticides safety education and pesticide applicator regulation are designed to protect the public from pesticide misuse , but do not eliminate all misuse. Reducing the use of pesticides and choosing less toxic pesticides may reduce risks placed on society and the environment from pesticide use. Pesticides may affect health negatively. mimicking hormones causing reproductive problems, and also causing cancer. A 2007 systematic review found that "most studies on non-Hodgkin lymphoma and leukemia showed positive associations with pesticide exposure" and thus concluded that cosmetic use of pesticides should be decreased. There
3440-505: The decline was even steeper, due to the switchover to transgenic Bt corn . Pesticides increase agricultural yields and lower costs. One study found that not using pesticides reduced crop yields by about 10%. Another study, conducted in 1999, found that a ban on pesticides in the United States may result in a rise of food prices , loss of jobs, and an increase in world hunger. There are two levels of benefits for pesticide use, primary and secondary. Primary benefits are direct gains from
3520-554: The early prospecting in Persia of William Knox D'Arcy with Burmah Oil owning 97%. Burmah Oil became the largest oil company in the British Empire. The subsidiary was later renamed Anglo-Iranian Oil Company and eventually BP . For about a century, the company played a major role in the oil industry, and in the discovery of oil in the Middle East through its significant influence over British Petroleum. It marketed itself under
3600-502: The environment and human toxicity. DDT has become less effective, as resistance was identified in Africa as early as 1955, and by 1972 nineteen species of mosquito worldwide were resistant to DDT. Total pesticides use in agriculture in 2021 was 3.54 million tonnes of active ingredients (Mt), a 4 percent increase with respect to 2020, an 11 percent increase in a decade, and a doubling since 1990. Pesticides use per area of cropland in 2021
3680-409: The exact biological mechanism which the pesticide disrupts. The modes of action are important for resistance management, and are categorized and administered by the insecticide , herbicide , and fungicide resistance action committees. Pesticides may be systemic or non-systemic. A systemic pesticide moves (translocates) inside the plant. Translocation may be upward in the xylem , or downward in
3760-589: The field is often impractical and many methods are not sensitive enough to detect low-level concentrations. Rapid cholinesterase test kits exist to collect blood samples in the field. Conducting large scale assessments of agricultural workers in remote regions of developing countries makes the implementation of these kits a challenge. The cholinesterase assay is a useful clinical tool to assess individual exposure and acute toxicity. Considerable variability in baseline enzyme activity among individuals makes it difficult to compare field measurements of cholinesterase activity to
3840-523: The first ever well drilled with percussion tools to a depth of 21 meters for oil exploration. In 1878 Ludvig Nobel and his Branobel company "revolutionized oil transport" by commissioning the first oil tanker and launching it on the Caspian Sea . Samuel Kier established America's first oil refinery in Pittsburgh on Seventh avenue near Grant Street in 1853. Ignacy Łukasiewicz built one of
3920-555: The first modern oil-refineries near Jasło (then in the Austrian dependent Kingdom of Galicia and Lodomeria in Central European Galicia ), present-day Poland, in 1854–56. Galician refineries were initially small, as demand for refined fuel was limited. The refined products were used in artificial asphalt, machine oil and lubricants, in addition to Łukasiewicz's kerosene lamp . As kerosene lamps gained popularity,
4000-617: The first offshore oil-drilling at Oil Rocks (Neft Dashlari) in the Caspian Sea off Azerbaijan eventually resulted in a city built on pylons. In the 1960s and 1970s, multi-governmental organizations of oil–producing nations – OPEC and OAPEC – played a major role in setting petroleum prices and policy. Oil spills and their cleanup have become an issue of increasing political, environmental, and economic importance. New fields of hydrocarbon production developed in places such as Siberia, Sakhalin , Venezuela and North and West Africa. With
4080-578: The first oil discovery drilled out of sight of land. Forty-four Gulf of Mexico exploratory wells discovered 11 oil and natural gas fields by the end of 1949. During World War II (1939–1945) control of oil supply from Romania, Baku, the Middle East and the Dutch East Indies played a huge role in the events of the war and the ultimate victory of the Allies . The Anglo-Soviet invasion of Iran (1941) secured Allied control of oil-production in
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#17327658178084160-631: The first true modern oil well , touched off a major boom. In the first quarter of the 20th century, the United States overtook Russia as the world's largest oil producer. By the 1920s, oil fields had been established in many countries including Canada, Poland, Sweden, Ukraine, the United States, Peru and Venezuela. The first successful oil tanker , the Zoroaster , was built in 1878 in Sweden, designed by Ludvig Nobel . It operated from Baku to Astrakhan . A number of new tanker designs developed in
4240-812: The forefront of the industry as this new technology plays a crucial and controversial role in new methods of oil extraction. Some petroleum industry operations have been responsible for water pollution through by-products of refining and oil spills . Though hydraulic fracturing has significantly increased natural gas extraction, there is some belief and evidence to support that consumable water has seen increased in methane contamination due to this gas extraction. Leaks from underground tanks and abandoned refineries may also contaminate groundwater in surrounding areas. Hydrocarbons that comprise refined petroleum are resistant to biodegradation and have been found to remain present in contaminated soils for years. To hasten this process, bioremediation of petroleum hydrocarbon pollutants
4320-503: The future of the industry. Pesticide Pesticides are substances that are used to control pests . They include herbicides , insecticides , nematicides , fungicides , and many others (see table). The most common of these are herbicides, which account for approximately 50% of all pesticide use globally. Most pesticides are used as plant protection products (also known as crop protection products), which in general protect plants from weeds , fungi, or insects . In general,
4400-608: The general population, and many others that are specific to occupational exposures of agricultural workers. Beyond farm workers, estimating exposure to family members and children presents additional challenges, and may occur through "take-home" exposure from pesticide residues collected on clothing or equipment belonging to parent farm workers and inadvertently brought into the home. Children may also be exposed to pesticides prenatally from mothers who are exposed to pesticides during pregnancy. Characterizing children's exposure resulting from drift of airborne and spray application of pesticides
4480-505: The growth of the pesticide industry. During this period, it became increasingly evident that DDT, which had been sprayed widely in the environment to combat the vector, had accumulated in the food chain . It had become a global pollutant, as summarized in the well-known book Silent Spring .Finally, DDT was banned in the 1970s in several countries, and subsequently all persistent pesticides were banned worldwide, an exception being spraying on interior walls for vector control. Resistance to
4560-539: The industry are fuel oil and gasoline (petrol). Petroleum is also the raw material for many chemical products , including pharmaceuticals , solvents , fertilizers , pesticides , synthetic fragrances , and plastics . The industry is usually divided into three major components: upstream , midstream , and downstream . Upstream regards exploration and extraction of crude oil , midstream encompasses transportation and storage of crude, and downstream concerns refining crude oil into various end products . Petroleum
4640-417: The largest consumers. The United States consumed 18% of the oil produced in 2015. The production, distribution, refining, and retailing of petroleum taken as a whole represents the world's largest industry in terms of dollar value. Petroleum is a naturally occurring liquid found in rock formations. It consists of a complex mixture of hydrocarbons of various molecular weights, plus other organic compounds. It
4720-539: The largest industries. In East Africa, the agricultural industry represents one of the largest sectors of the economy, with nearly 80% of its population relying on agriculture for income. Farmers in these communities rely on pesticide products to maintain high crop yields. Some East Africa governments are shifting to corporate farming , and opportunities for foreign conglomerates to operate commercial farms have led to more accessible research on pesticide use and exposure among workers. In other areas where large proportions of
4800-440: The magnitude of the inhibitory effect of organophosphate and carbamate pesticides. Another method of quantifying exposure involves measuring, at the molecular level, the amount of pesticide interacting with the site of action. These methods are more commonly used for occupational exposures where the mechanism of action is better understood, as described by WHO guidelines published in "Biological Monitoring of Chemical Exposure in
4880-412: The method of choice in one third of suicides worldwide, and recommended, among other things, more restrictions on the types of pesticides that are most harmful to humans. A 2014 epidemiological review found associations between autism and exposure to certain pesticides, but noted that the available evidence was insufficient to conclude that the relationship was causal. The World Health Organization and
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#17327658178084960-416: The optimized compounds must meet several requirements. In addition to being potent (low application rate), they must show low toxicity to non-target organisms, low environmental impact, and viable manufacturing cost. The cost of developing a pesticide in 2022 was estimated to be 350 million US dollars. It has become more difficult to find new pesticides. More than 100 new active ingredients were introduced in
5040-412: The parent compound or its metabolites in various types of media: urine, blood, serum. Biomarkers may include a direct measurement of the compound in the body before it's been biotransformed during metabolism. Other suitable biomarkers may include the metabolites of the parent compound after they've been biotransformed during metabolism. Toxicokinetic data can provide more detailed information on how quickly
5120-1144: The partial bans on neonicotinoids . Revised 2023 guidance by registration authorities describes the bee testing that is required for new insecticides to be approved for commercial use. In addition to their main use in agriculture , pesticides have a number of other applications. Pesticides are used to control organisms that are considered to be harmful, or pernicious to their surroundings. For example, they are used to kill mosquitoes that can transmit potentially deadly diseases like West Nile virus , yellow fever , and malaria . They can also kill bees , wasps or ants that can cause allergic reactions. Insecticides can protect animals from illnesses that can be caused by parasites such as fleas . Pesticides can prevent sickness in humans that could be caused by moldy food or diseased produce. Herbicides can be used to clear roadside weeds, trees, and brush. They can also kill invasive weeds that may cause environmental damage. Herbicides are commonly applied in ponds and lakes to control algae and plants such as water grasses that can interfere with activities like swimming and fishing and cause
5200-554: The pesticidal activity in a new compound is found in one enantiomer (the eutomer ), the registration and use of the compound as this single enantiomer is preferred. This reduces the total application rate and avoids the tedious environmental testing required when registering a racemate. However if a viable enantioselective manufacturing route cannot be found, then the racemate is registered and used. Insecticides with systemic activity against sucking pests, which are safe to pollinators , are sought after, particularly in view of
5280-399: The plant extracts contained pyrethrum , nicotine , and rotenone among others. The less toxic of these are still in use in organic farming . In the 1940s the insecticide DDT , and the herbicide 2,4-D , were introduced. These synthetic organic compounds were widely used and were very profitable. They were followed in the 1950s and 1960s by numerous other synthetic pesticides, which led to
5360-531: The population rely on subsistence, small-scale farming, estimating pesticide use and exposure is more difficult. Pesticides may exhibit toxic effects on humans and other non-target species, the severity of which depends on the frequency and magnitude of exposure. Toxicity also depends on the rate of absorption, distribution within the body, metabolism, and elimination of compounds from the body. Commonly used pesticides like organophosphates and carbamates act by inhibiting acetylcholinesterase activity, which prevents
5440-590: The refining industry grew in the area. The first commercial oil-well in Canada became operational in 1858 at Oil Springs, Ontario (then Canada West ). Businessman James Miller Williams dug several wells between 1855 and 1858 before discovering a rich reserve of oil four metres below ground. Williams extracted 1.5 million litres of crude oil by 1860, refining much of it into kerosene-lamp oil. Some historians challenge Canada's claim to North America's first oil field , arguing that Pennsylvania 's famous Drake Well
5520-553: The rescue operation was the provision of a year's grace so that the company could become smaller and more viable. The Bank of England also agreed to guarantee $ 650 million of the company's foreign currency borrowings. In 2000, Burmah was acquired by BP Amoco . Oil company The petroleum industry , also known as the oil industry , includes the global processes of exploration , extraction , refining , transportation (often by oil tankers and pipelines ), and marketing of petroleum products . The largest volume products of
5600-558: The rights over the largest oil reserves; by this measure the top ten companies all are NOC. The following table shows the ten largest national oil companies ranked by reserves and by production in 2012. Most upstream work in the oil field or on an oil well is contracted out to drilling contractors and oil field service companies. Aside from the NOCs which dominate the Upstream sector, there are many international companies that have
5680-421: The risk of pesticide poisoning, including dermal absorption walking through fields and applying products, as well as inhalation exposure. There are multiple approaches to measuring a person's exposure to pesticides, each of which provides an estimate of an individual's internal dose. Two broad approaches include measuring biomarkers and markers of biological effect. The former involves taking direct measurement of
5760-475: The target organisms listed in the table. A structural class is usually associated with a single mode of action , whereas a mode of action may encompass more than one structural class. The pesticidal chemical ( active ingredient ) is mixed ( formulated ) with other components to form the product that is sold, and which is applied in various ways. Pesticides in gas form are fumigants . Pesticides can be classified based upon their mode of action , which indicates
5840-602: The turn of the 20th century, Imperial Russia's output of oil, almost entirely from the Apsheron Peninsula , accounted for half of the world's production and dominated international markets. Nearly 200 small refineries operated in the suburbs of Baku by 1884. As a side effect of these early developments, the Apsheron Peninsula emerged as the world's "oldest legacy of oil pollution and environmental negligence". In 1846 Baku (Bibi-Heybat settlement) featured
5920-442: The use of pesticides and secondary benefits are effects that are more long-term. Controlling pests and plant disease vectors Controlling human/livestock disease vectors and nuisance organisms Controlling organisms that harm other human activities and structures In 2018 world pesticide sales were estimated to be $ 65 billion, of which 88% was used for agriculture. Generic accounted for 85% of sales in 2018. In one study, it
6000-415: The water to look or smell unpleasant. Uncontrolled pests such as termites and mold can damage structures such as houses. Pesticides are used in grocery stores and food storage facilities to manage rodents and insects that infest food such as grain. Pesticides are used on lawns and golf courses , partly for cosmetic reasons. Integrated pest management , the use of multiple approaches to control pests,
6080-415: The world’s total agricultural land. Pesticides have become more effective. Application rates fell from 1,000–2,500 grams of active ingredient per hectare (g/ha) in the 1950s to 40–100 g/ha in the 2000s. Despite this, amounts used have increased. In high income countries over 20 years between the 1990s and 2010s amounts used increased 20%, while in the low income countries amounts increased 1623%. The aim
6160-478: Was 2.26 kg per hectare (kg/ha), an increase of 4 percent with respect to 2020; use per value of agricultural production was 0.86 kg per thousand international dollar (kg/1000 I$ ) (+2%); and use per person was 0.45 kg per capita (kg/cap) (+3%). Between 1990 and 2021, these indicators increased by 85 percent, 3 percent, and 33 percent, respectively. Brazil was the world's largest user of pesticides in 2021, with 720 kt of pesticides applications for agricultural use, while
6240-450: Was estimated that for every dollar ($ 1) that is spent on pesticides for crops results in up to four dollars ($ 4) in crops which would otherwise be lost to insects, fungi and weeds. In general, farmers benefit from having an increase in crop yield and from being able to grow a variety of crops throughout the year. Consumers of agricultural products also benefit from being able to afford the vast quantities of produce available year-round. On
6320-642: Was specifically reversed by the War Damage Act 1965 . In 1963, the company left Burma and undertook new exploration in India, Pakistan, Bangladesh, Australasia, the Americas, Canada and the North Sea until 1986. In 1966, Burmah acquired Castrol renaming it Burmah-Castrol. The Bank of England came to the rescue of Burmah Oil after the company made large losses on its tanker fleets in 1974. The core of
6400-411: Was the continent's first. But there is evidence to support Williams, not least of which is that the Drake well did not come into production until August 28, 1859. The controversial point might be that Williams found oil above bedrock while Edwin Drake 's well located oil within a bedrock reservoir . The discovery at Oil Springs touched off an oil boom which brought hundreds of speculators and workers to
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