The Feinstein Institutes for Medical Research in Manhasset , Nassau County , New York , United States, on Long Island , constitute the research arm of Northwell Health . Feinstein is home to 50 research labs, 2,500 clinical research studies, and 5,000 professional and support staff. Feinstein scientists conduct research in molecular medicine, genetics, cancer, brain research, mental health, autoimmunity and bioelectronic medicine, among others. Feinstein is the laboratory and faculty home of the Elmezzi Graduate School of Molecular Medicine . Students with an MD degree may earn a PhD in molecular medicine via the Zucker School of Medicine , as part of the medical school's MD/PhD or PhD programs.
14-529: The Feinstein Institutes acquired assets from the closing of the Picower Institute for Medical Research, founded in 1991 by Anthony Cerami and funded by Jeffry Picower . In 2001 the institute's funding was withdrawn and it closed; in 2002 it was acquired by The Institute for Medical Research at North Shore-LIJ . In 2005 board member Leonard Feinstein, co-founder of Bed Bath & Beyond , made
28-588: A $ 25 million gift that led to its renaming The Feinstein Institute for Medical Research . In 2017, Feinstein and his wife, Susan, committed another $ 25 million. In 2024, Feinstein Institutes for Medical Research comprises the following five institutes: Feinstein publishes two open-access , international peer-reviewed medical journals in partnership with BioMed Central , part of Springer Nature : Molecular Medicine and Bioelectronic Medicine . The Feinstein Institutes bestow two major academic awards:
42-571: A Ph.D. in 1967 from Rockefeller University , New York, completed postdoctoral fellowships at Harvard Medical School and at the Jackson Laboratory and served for 20 years as Professor and Head of the Laboratory of Medical Biochemistry, and Dean of Graduate and Postgraduate Studies at Rockefeller. In late 1986 Cerami was a founder of Alteon, Inc. which licensed patents filed by Rockefeller on work Cerami had done there; Cerami took
56-554: A combination of low intake and high loss. Infections and conditions associated with wasting include tuberculosis , chronic diarrhea , AIDS , and superior mesenteric artery syndrome . The mechanism may involve cachectin – also called tumor necrosis factor, a macrophage -secreted cytokine . Caretakers and health providers can sometimes contribute to wasting if the patient is placed on an improper diet. Voluntary weight loss and eating disorders are excluded as causes of wasting. Cutoff points may vary, but <80% (close to −2 Z-score )
70-498: A measurement of glycated hemoglobin to monitor control of blood sugar in people with diabetes, and a paper he published in 1985 using polyclonal antibodies against tumour necrosis factor-alpha was important in the field of immunology for demonstrating that TNF-alpha causes disease and blocking it could be a treatment. Work that he did while he was at Rockefeller on advanced glycation end-products (AGEs) and protein cross-linking and their roles in metabolic diseases and aging
84-411: A seat on the board of the company, was on the scientific advisory board, and received research funding from Alteon first at Rockefeller and then at Picower, and later through his consulting company and the "Kenneth S. Warren Laboratories, Inc." In the spring of 1999 Alteon and Cerami terminated the consulting agreement and research agreement with Warren Labs, and Cerami resigned from the board. Cerami
98-595: Is sometimes referred to as "acute malnutrition" because it is believed that episodes of wasting have a short duration, in contrast to stunting , which is regarded as chronic malnutrition. An estimated 45 million children under 5 years of age (or 6.7%) were wasted in 2021. Prevalence is highest in Southern Asia , followed by Oceania (excluding Australia and New Zealand) and South-eastern Asia . Wasting can be caused by an extremely low energy intake (e.g., caused by famine ), nutrient losses due to infection , or
112-457: The "Kenneth S. Warren Laboratories, Inc. The Picower Institute was closed down by Picower in 2001, and early the next year it was acquired by The Institute for Medical Research at North Shore-LIJ. As of 2001, Cerami was the director and lead researcher of the Kenneth S. Warren Institute , and in 2001, Warren Pharmaceuticals was formed to commercialize inventions made at the institute; Cerami
126-790: The Anthony Cerami Award in Translational Medicine, starting in 2013, and the Ross Prize in Molecular Medicine. Feinstein has the standard support services and scientific cores to support basic research. Support includes: The cores include: In 2016, the Feinstein Institutes for Medical Research agreed to pay the U.S. Department of Health and Human Services, Office for Civil Rights (OCR), $ 3.9 million to settle potential violations of
140-503: The Health Insurance Portability and Accountability Act of 1996 (HIPAA) privacy and security rules and to undertake a substantial corrective action plan to bring its operations into compliance. Anthony Cerami Anthony Cerami (born October 3, 1940 ) is an American entrepreneur and medical research scientist. Anthony Cerami received his undergraduate degree from Rutgers University and received
154-513: Was chairman of the board. Cerami has led research programs into genetic, metabolic and infectious diseases, with the goal of translating scientific discovery into drugs and diagnostic tests. He received funding from the Rockefeller Foundation to study neglected tropical diseases and traveled to Africa, where he became interested in the wasting , one of the symptoms of African sleeping sickness . He developed and validated
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#1732802096630168-489: Was one of 15 Rockefeller faculty who vocally opposed the appointment of David Baltimore as president of Rockefeller in 1989. Due in part to that disagreement, in 1991 Cerami left Rockefeller to found (with Jeffry Picower ) the Picower Institute for Medical Research on the grounds of North Shore University Hospital . As of March 1998, Cerami was President of Cerami Consulting and was president and Trustee of
182-456: Was patented by Rockfeller and licensed to Alteon Inc. in 1987 and in 1992 the company licensed further work that Cerami did on the use of pimagedine to reduce AGEs. At the Warren institutes, he led work on erythropoietin derivatives that were called "tissue protective cytokines"; this work was licensed to Warren Pharmaceuticals and through them to Lundbeck in 2001; the development program
196-702: Was terminated in 2007. He is the recipient of the Luft Award in Diabetes and the Frederick Banting Medal for Scientific Achievement, awarded by the American Diabetes Association in recognition of his lifelong work on diabetes. Wasting In medicine, wasting , also known as wasting syndrome , refers to the process by which a debilitating disease causes muscle and fat tissue to "waste" away. Wasting
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