Orf is a farmyard pox , a type of zoonosis . It causes small pustules in the skin of primarily sheep and goats , but can also occur on the hands of humans. A pale halo forms around a red centre. It may persist for several weeks before crusting and then either resolves or leaves a hard lump . There is usually only one lesion, but there may be many, and they are not painful. Sometimes there are swollen lymph glands .
16-516: [REDACTED] Look up orf in Wiktionary, the free dictionary. ORF or Orf may refer to: Norfolk International Airport , IATA airport code ORF Observer Research Foundation , an Indian research institute One Race Films , a film production company founded by Vin Diesel Open reading frame , a portion of the genome that has
32-496: A cutaneous condition ORF format , Olympus raw image file format with extension .orf Orf, Iran , a village in Kohgiluyeh and Boyer-Ahmad Province, Iran See also [ edit ] Orff (disambiguation) Orfe ORFS Topics referred to by the same term [REDACTED] This disambiguation page lists articles associated with the title ORF . If an internal link led you here, you may wish to change
48-761: A film production company founded by Vin Diesel Open reading frame , a portion of the genome that has the potential to code for a protein Open Road Films , a joint venture of Regal Entertainment Group and AMC Theatres Operation River Falcon , a military operation in the Iraq War Operation Royal Flush , a military deception employed by the Allied Nations during the Second World War ORF (broadcaster) , Austrian public service broadcaster Orf (disease) ,
64-453: A person can still be infected again. Generally, treatment options are limited. Injecting the lesion with cidofovir or applying imiquimod has been tried. It is sometimes necessary to cut them out . The vaccine used in sheep to prevent orf is live and has been known to cause disease in humans. The disease is endemic in livestock herds worldwide. A recent outbreak emerged in southwest Ethiopia between October 2019 and May 2020. Orf
80-562: A village in Kohgiluyeh and Boyer-Ahmad Province, Iran See also [ edit ] Orff (disambiguation) Orfe ORFS Topics referred to by the same term [REDACTED] This disambiguation page lists articles associated with the title ORF . If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=ORF&oldid=1105813457 " Category : Disambiguation pages Hidden categories: Short description
96-440: Is a zoonotic disease , meaning humans can contract this disorder through direct contact with infected sheep and goats or with fomites carrying the orf virus. It causes a purulent -appearing papule locally and generally no systemic symptoms. Infected locations can include the finger, hand, arm, face and even the penis (caused by infection either from contact with the hand during urination or from bestiality ). Consequently, it
112-432: Is different from Wikidata All article disambiguation pages All disambiguation pages orf (Redirected from Orf ) [REDACTED] Look up orf in Wiktionary, the free dictionary. ORF or Orf may refer to: Norfolk International Airport , IATA airport code ORF Observer Research Foundation , an Indian research institute One Race Films ,
128-454: Is important to observe good personal hygiene and to wear gloves when treating infected animals. It may appear similar to cowpox and pseudocowpox . While orf is usually a benign self-limiting illness which resolves in 3-6 weeks, in the immunocompromised it can be very progressive and even life-threatening. One percent topical cidofovir has been successfully used in a few patients with progressive disease. Serious damage may be inflicted on
144-401: The buccal cavity , cheeks, tongue and lips. Another severe case was reported pharyngitis , genital lesions and infection of the hooves which led to lameness and, in some cases, sloughing of the hoof. More typically, sheep will become free of orf within a week or so as the disease runs its course. Sheep custodians can assist by ensuring infected lambs receive sufficient milk and separating out
160-406: The animal does not produce an immune response. A live virus vaccine ( ATCvet code: QI04AD01 ( WHO )) is made from scab material and usually given to ewes at the age of two months, but only to lambs when there is an outbreak. The vaccine can cause disease in humans. In sheep and goats, the lesions mostly appear on or near the hairline and elsewhere on the lips and muzzle. In some cases
176-427: The eye if it is infected by orf, even among healthy individuals. The virus can survive in the soil for at least six months. Orf is primarily a disease of sheep and goats although it has been reported as a natural disease in humans , steenbok and alpacas , chamois and tahrs , reindeer , musk oxen , dogs , cats , mountain goats , bighorn sheep , dall sheep , and red squirrels . It has been recorded since
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#1732776858182192-587: The late 19th century and has been reported from most sheep-or goat-raising areas, including those in Europe, the Middle East, the United States, Africa, Asia, South America, Canada, New Zealand and Australia. Orf is spread by fomites and direct contact. In some environments, infection is injected by scratches from thistles of both growing and felled plants. Symptoms include papules and pustules on
208-453: The lesions appear on and in the nostrils, around the eyes, on the thigh, coronet, vulva , udder, and axilla . In rare cases, mostly involving young lambs, lesions are found on the tongue, gums, roof of the mouth and the esophagus . It has also been reported a number of times to cause lesions in the rumen . In one case it was shown that a severe form of orf virus caused an outbreak involving the gastrointestinal tract , lungs, heart, as well as
224-540: The link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=ORF&oldid=1105813457 " Category : Disambiguation pages Hidden categories: Short description is different from Wikidata All article disambiguation pages All disambiguation pages Orf (disease) It is caused by a Parapoxvirus . It can occur in humans who handle infected animals or contaminated objects. One third of cases may develop erythema multiforme . Once resolved,
240-420: The lips and muzzle , and less commonly in the mouth of young lambs and on the eyelids, feet, and teats of ewes. The lesions progress to thick crusts which may bleed. Orf in the mouths of lambs may prevent suckling and cause weight loss, and can infect the udder of the mother ewe, thus potentially leading to mastitis . Sheep are prone to reinfection. Occasionally the infection can be extensive and persistent if
256-482: The potential to code for a protein Open Road Films , a joint venture of Regal Entertainment Group and AMC Theatres Operation River Falcon , a military operation in the Iraq War Operation Royal Flush , a military deception employed by the Allied Nations during the Second World War ORF (broadcaster) , Austrian public service broadcaster Orf (disease) , a cutaneous condition ORF format , Olympus raw image file format with extension .orf Orf, Iran ,
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