The Ottawa Hospital Research Institute ( OHRI ), formerly Ottawa Health Research Institute , is a non-profit academic health research institute located in the city of Ottawa . It was formed in 2001 following the merger of three Ottawa hospitals. The Ottawa Hospital Research Institute is the research arm of The Ottawa Hospital and affiliated with the University of Ottawa .
7-585: As of 2022, the Ottawa Hospital Research Institute houses approximately 2,200 scientists, clinician investigators, students, research fellows, and support staff. It has five research programs: Cancer Therapeutics; Chronic Disease; Clinical Epidemiology; Regenerative Medicine; and Neurosciences. Its researchers are studying more than a hundred different diseases, conditions and specialties with an overall focus on translating discoveries and knowledge into better health. Ronald G. Worton
14-575: Is a Canadian doctor. Born in Winnipeg , Manitoba , he earned a BSc and MSc from the University of Manitoba and a PhD in medical biophysics from the University of Toronto . Worton pursued post-doctoral studies at Yale University . In 1971, he became director of the diagnostic cytogenetics laboratory at The Hospital for Sick Children in Toronto . Worton became geneticist in chief at
21-793: Is a live replicating virus vaccine using a vaccinia virus vector. Results from pre-clinical studies were published in Molecular Therapy in October 2021. The research team was led by John Bell and was funded by the Thistledown Foundation, Ottawa Hospital Foundation and the Canadian Institutes of Health Research . 45°23′35″N 75°43′26″W / 45.39307°N 75.72391°W / 45.39307; -75.72391 Ronald G. Worton Ronald G. Worton OC FRSC (born April 2, 1942)
28-923: The Canadian Stem Cell Network . He was awarded a Gairdner Foundation International Award in 1989, was named an officer of the Order of Canada in 2012 and is a fellow of the Royal Society of Canada . He has also received the E. Mead Johnson Award for pediatrics research. In 2014, Worton was inducted into the Canadian Medical Hall of Fame . Worton has retired from medical research and lives in Oakville, Ontario , spending his winters in Mesa, Arizona . Canadian Medical Hall of Fame The Canadian Medical Hall of Fame
35-705: The genetics department at The Hospital for Sick Children also identified genes associated with cystic fibrosis , Fanconi anemia , Wilson's disease , Wilms' tumor and Tay–Sachs disease . Worton served four years on the board of the Human Genome Organization , twelve years as associate director for the Canadian Genetic Diseases network, six years as head of the Canadian Genome Analysis and Technology Program and four years as founding scientific director of
42-576: The hospital and professor of Medical Genetics at the University of Toronto in 1985. In 1996, he became director of research at the Ottawa General Hospital and chief executive officer of the Ottawa Hospital Research Institute, as well as professor of medicine, University of Ottawa. Worton and his team identified the dystrophin gene whose mutation is associated with Duchenne and Becker muscular dystrophies . Under his leadership,
49-568: Was the research institute's founding CEO and Scientific Director in 2001. In 2007, Duncan Stewart , formerly Chief Cardiologist of St. Michael's Hospital in Toronto and Director of Cardiology of University of Toronto , took over as CEO and Scientific Director. During the COVID-19 pandemic , scientists at the OHRI developed an early-stage COVID-19 vaccine candidate called TOH-Vac1. The candidate
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