5-421: LMP1 may refer to: Epstein–Barr virus latent membrane protein 1 Le Mans Prototype , a type of sports prototype race car GMS Durango LMP1 , a Le Mans Prototype built for Durango by GMS in 2000 Panoz LMP-1 Roadster-S , a Le Mans Prototype built for Panoz in 1999 See also [ edit ] LMP (disambiguation) [REDACTED] Topics referred to by
10-410: A long cytoplasmic C-terminus , which contains three activating domains: CTARt, CTAR2, and CTAR3. Each CTAR domain contains an amino acid sequence that serves as a recognition site for cellular adaptors to bind and trigger a series of signal transduction pathways that can lead to a change in gene expression . LMP-1 is a functional homologue of tumor necrosis factor and mediates signaling through
15-420: Is different from Wikidata All article disambiguation pages All disambiguation pages Epstein%E2%80%93Barr virus latent membrane protein 1 Epstein–Barr virus latent membrane protein 1 ( LMP1 ) is an Epstein–Barr virus (EBV) protein that regulates its own expression and the expression of human genes. It has a molecular weight of approximately 63 kDa , and its expression induces many of
20-460: The changes associated with EBV infections and activation of primary B cells . LMP1 is the best-documented oncoprotein of the EBV latent gene products , as it is expressed in most EBV-related human cancers such as the various malignant Epstein-Barr virus-associated lymphoproliferative diseases . The structure of LMP1 consists of a short cytoplasmic terminal tail , six trans-membrane domains , and
25-449: The same term This disambiguation page lists articles associated with the same title formed as a letter–number combination. If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=LMP1&oldid=1159701326 " Category : Letter–number combination disambiguation pages Hidden categories: Short description
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