Misplaced Pages

Montreal Neurological Institute and Hospital

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.

The Montreal Neurological Institute-Hospital (MNI) , also known as Montreal Neuro or The Neuro , is a research and medical centre dedicated to neuroscience , training and clinical care, located in the city's downtown core of Montreal , Quebec , Canada. It is part of the McGill University Health Centre network and is situated on the southern slope of Mount Royal along the east side of University Street, just north of Pine Avenue. It was founded in 1934 by neurosurgeon Wilder Penfield , who developed the Montreal procedure there for the treatment of epilepsy.

#621378

93-665: The Montreal Neurological Institute originated from the Sub-Department of Neurosurgery at the Royal Victoria Hospital . The Neuro was created at the RVH in 1933, before it moved to its newly-constructed building across University Street. The cornerstone of The Neuro was laid on October 6, 1933. On September 27, 1934 Sir Edward Beatty, chancellor of McGill University , declared the institute formally opened. The Rockefeller Foundation provided funds to build and equip

186-452: A concept devised by Mark Shriver and Tony Frudakis , is not an objective measure of the biological aspects of race as Shriver and Frudakis claim it is. She argues that it is actually just a "local category shaped by the U.S. context of its production, especially the forensic aim of being able to predict the race or ethnicity of an unknown suspect based on DNA found at the crime scene". Recent studies of human genetic clustering have included

279-602: A concept often translated as "race" was associated with supposed common descent from the Yellow Emperor , and used to stress the unity of ethnic groups in China. Brutal conflicts between ethnic groups have existed throughout history and across the world. The first post- Graeco-Roman published classification of humans into distinct races seems to be François Bernier 's Nouvelle division de la terre par les différents espèces ou races qui l'habitent ("New division of Earth by

372-404: A debate over how genetic variation is organized, with clusters and clines as the main possible orderings. Serre & Pääbo (2004) argued for smooth, clinal genetic variation in ancestral populations even in regions previously considered racially homogeneous, with the apparent gaps turning out to be artifacts of sampling techniques. Rosenberg et al. (2005) disputed this and offered an analysis of

465-583: A given society . The term came into common usage during the 16th century, when it was used to refer to groups of various kinds, including those characterized by close kinship relations. By the 17th century, the term began to refer to physical ( phenotypical ) traits, and then later to national affiliations. Modern science regards race as a social construct , an identity which is assigned based on rules made by society. While partly based on physical similarities within groups, race does not have an inherent physical or biological meaning. The concept of race

558-405: A great deal more diversity than elsewhere and that diversity should decrease the further from Africa a population is sampled. Hence, the 85% average figure is misleading: Long and Kittles find that rather than 85% of human genetic diversity existing in all human populations, about 100% of human diversity exists in a single African population, whereas only about 60% of human genetic diversity exists in

651-517: A host of other similarities and differences (for example, blood type) that do not correlate highly with the markers for race. Thus, anthropologist Frank Livingstone's conclusion was that, since clines cross racial boundaries, "there are no races, only clines". In a response to Livingstone, Theodore Dobzhansky argued that when talking about race one must be attentive to how the term is being used: "I agree with Dr. Livingstone that if races have to be 'discrete units', then there are no races, and if 'race'

744-532: A joint gift of C$ 1,000,000 for the construction of a free hospital in Montreal and purchased a site on Mount Royal for a further C$ 86,000. The site they bought was the old Frothingham estate that covered ten acres of land. During 1897 and 1898, Smith and Stephen gave another C$ 1,000,000 between them in Great Northern Railroad securities to establish an endowment fund to maintain

837-723: A large multiethnic population in the United States, and "detected only modest genetic differentiation between different current geographic locales within each race/ethnicity group. Thus, ancient geographic ancestry, which is highly correlated with self-identified race/ethnicity – as opposed to current residence – is the major determinant of genetic structure in the U.S. population." Witherspoon et al. (2007) have argued that even when individuals can be reliably assigned to specific population groups, it may still be possible for two randomly chosen individuals from different populations/clusters to be more similar to each other than to

930-635: A locus-by-locus analysis of variation to derive taxonomy, it is possible to construct a human classification system based on characteristic genetic patterns, or clusters inferred from multilocus genetic data . Geographically based human studies since have shown that such genetic clusters can be derived from analyzing of a large number of loci which can assort individuals sampled into groups analogous to traditional continental racial groups. Joanna Mountain and Neil Risch cautioned that while genetic clusters may one day be shown to correspond to phenotypic variations between groups, such assumptions were premature as

1023-454: A product of the colonial enterprises of European powers from the 16th to 18th centuries which identified race in terms of skin color and physical differences. Author Rebecca F. Kennedy argues that the Greeks and Romans would have found such concepts confusing in relation to their own systems of classification. According to Bancel et al., the epistemological moment where the modern concept of race

SECTION 10

#1732779471622

1116-413: A race for political reasons. When people define and talk about a particular conception of race, they create a social reality through which social categorization is achieved. In this sense, races are said to be social constructs. These constructs develop within various legal, economic, and sociopolitical contexts, and may be the effect, rather than the cause, of major social situations. While race

1209-449: A randomly chosen member of their own cluster. They found that many thousands of genetic markers had to be used in order for the answer to the question "How often is a pair of individuals from one population genetically more dissimilar than two individuals chosen from two different populations?" to be "never". This assumed three population groups separated by large geographic ranges (European, African and East Asian). The entire world population

1302-458: A social construct, differences in genetic ancestry that happen to correlate to many of today's racial constructs are real". In response to Reich, a group of 67 scientists from a broad range of disciplines wrote that his concept of race was "flawed" as "the meaning and significance of the groups is produced through social interventions". Although commonalities in physical traits such as facial features, skin color, and hair texture comprise part of

1395-628: Is a hospital in Montreal , Quebec , Canada . It forms the largest base hospital of the McGill University Health Centre (MUHC), which is affiliated with McGill University . The hospital was established in 1893 and was based at Pine Avenue , now known as the Legacy site, until 2015, when major hospital operations were moved to the Glen site (1001 Décarie Boulevard ), named for the former Glen railway yards. The future uses of

1488-405: Is a broad scientific agreement that essentialist and typological conceptions of race are untenable, scientists around the world continue to conceptualize race in widely differing ways. While some researchers continue to use the concept of race to make distinctions among fuzzy sets of traits or observable differences in behavior, others in the scientific community suggest that the idea of race

1581-447: Is a natural taxonomy of the human species, because multiple other genetic patterns can be found in human populations that crosscut racial distinctions. Moreover, the genomic data underdetermines whether one wishes to see subdivisions (i.e., splitters) or a continuum (i.e., lumpers) . Under Kaplan and Winther's view, racial groupings are objective social constructions (see Mills 1998 ) that have conventional biological reality only insofar as

1674-408: Is also observed for many alleles that vary from one human group to another. Another observation is that traits or alleles that vary from one group to another do not vary at the same rate. This pattern is referred to as nonconcordant variation. Because the variation of physical traits is clinal and nonconcordant, anthropologists of the late 19th and early 20th centuries discovered that the more traits and

1767-406: Is compatible with the observation that most human genetic variation is found within populations, not between them. It is also compatible with our finding that, even when the most distinct populations are considered and hundreds of loci are used, individuals are frequently more similar to members of other populations than to members of their own population." Anthropologists such as C. Loring Brace ,

1860-499: Is foundational to racism , the belief that humans can be divided based on the superiority of one race over another. Social conceptions and groupings of races have varied over time, often involving folk taxonomies that define essential types of individuals based on perceived traits. Modern scientists consider such biological essentialism obsolete, and generally discourage racial explanations for collective differentiation in both physical and behavioral traits. Even though there

1953-487: Is frequently criticized for perpetuating an outmoded understanding of human biological variation, and promoting stereotypes. Because in some societies racial groupings correspond closely with patterns of social stratification , for social scientists studying social inequality, race can be a significant variable . As sociological factors, racial categories may in part reflect subjective attributions, self-identities , and social institutions. Scholars continue to debate

SECTION 20

#1732779471622

2046-634: Is inherently naive or simplistic. Still others argue that, among humans, race has no taxonomic significance because all living humans belong to the same subspecies , Homo sapiens sapiens . Since the second half of the 20th century, race has been associated with discredited theories of scientific racism , and has become increasingly seen as a largely pseudoscientific system of classification. Although still used in general contexts, race has often been replaced by less ambiguous and/or loaded terms: populations , people (s) , ethnic groups , or communities , depending on context. Its use in genetics

2139-416: Is much more complex and studying an increasing number of groups would require an increasing number of markers for the same answer. The authors conclude that "caution should be used when using geographic or genetic ancestry to make inferences about individual phenotypes". Witherspoon, et al. concluded: "The fact that, given enough genetic data, individuals can be correctly assigned to their populations of origin

2232-653: Is not necessarily any evolutionary significance to these observed differences, so this form of classification has become less acceptable to evolutionary biologists. Likewise this typological approach to race is generally regarded as discredited by biologists and anthropologists. In 2000, philosopher Robin Andreasen proposed that cladistics might be used to categorize human races biologically, and that races can be both biologically real and socially constructed. Andreasen cited tree diagrams of relative genetic distances among populations published by Luigi Cavalli-Sforza as

2325-518: Is now called scientific racism . After the Nazi eugenics program, along with the rise of anti-colonial movements, racial essentialism lost widespread popularity. New studies of culture and the fledgling field of population genetics undermined the scientific standing of racial essentialism, leading race anthropologists to revise their conclusions about the sources of phenotypic variation. A significant number of modern anthropologists and biologists in

2418-411: Is to say, found in diverse groups of people at different frequencies; (3) what was not cultural or polymorphic was principally clinal – that is to say, gradually variable over geography; and (4) what was left – the component of human diversity that was not cultural, polymorphic, or clinal – was very small. A consensus consequently developed among anthropologists and geneticists that race as

2511-422: Is understood to be a social construct by many, most scholars agree that race has real material effects in the lives of people through institutionalized practices of preference and discrimination . Socioeconomic factors, in combination with early but enduring views of race, have led to considerable suffering within disadvantaged racial groups. Racial discrimination often coincides with racist mindsets, whereby

2604-715: Is used as an 'explanation' of the human variability, rather than vice versa, then the explanation is invalid." He further argued that one could use the term race if one distinguished between "race differences" and "the race concept". The former refers to any distinction in gene frequencies between populations; the latter is "a matter of judgment". He further observed that even when there is clinal variation: "Race differences are objectively ascertainable biological phenomena ... but it does not follow that racially distinct populations must be given racial (or subspecific) labels." In short, Livingstone and Dobzhansky agree that there are genetic differences among human beings; they also agree that

2697-733: The Killam Trusts . In 1966, the Izaak Walton Killam Memorial Endowment Fund and Fund for Advanced Studies were established at the Montreal Neurological Institute through the bequest of Dorothy Johnston Killam. These funds support the academic and training mission of the Institute. Royal Victoria Hospital, Montreal The Royal Victoria Hospital ( RVH ), colloquially known as the " Royal Vic " or " The Vic ",

2790-458: The Out of Africa and Multiregional models). In the early 20th century, many anthropologists taught that race was an entirely biological phenomenon and that this was core to a person's behavior and identity, a position commonly called racial essentialism . This, coupled with a belief that linguistic , cultural, and social groups fundamentally existed along racial lines, formed the basis of what

2883-575: The Scottish baronial style of the Royal Infirmary of Edinburgh . From a medical perspective, his design of the Royal Vic was influenced by the ideas of Florence Nightingale as a Pavilion Hospital, in which the separation and isolation of both patients and diseases were thought to discourage the spread of infection. The original part of the building was completed in 1893. The hospital

Montreal Neurological Institute and Hospital - Misplaced Pages Continue

2976-431: The one-drop rule used in the 19th-century United States to exclude those with any amount of African ancestry from the dominant racial grouping, defined as " white ". Such racial identities reflect the cultural attitudes of imperial powers dominant during the age of European colonial expansion . This view rejects the notion that race is biologically defined. According to geneticist David Reich , "while race may be

3069-512: The world , they speculated about the physical, social, and cultural differences among various human groups. The rise of the Atlantic slave trade , which gradually displaced an earlier trade in slaves from throughout the world, created a further incentive to categorize human groups in order to justify the subordination of African slaves . Drawing on sources from classical antiquity and upon their own internal interactions – for example,

3162-532: The 1860s had made a name for himself in England and Scotland as a leading specialist in the design of hospitals, particularly in London . Constructed of Montreal limestone , the original Royal Vic is distinguished by its crenelated structures and romantic turrets framing generous sun porches at the corners of its imposing medical and surgical wards. Snell's aesthetic plans for the Royal Vic were inspired by

3255-800: The Human Genetic Diversity Panel showing that there were small discontinuities in the smooth genetic variation for ancestral populations at the location of geographic barriers such as the Sahara , the Oceans, and the Himalayas . Nonetheless, Rosenberg et al. (2005) stated that their findings "should not be taken as evidence of our support of any particular concept of biological race ... Genetic differences among human populations derive mainly from gradations in allele frequencies rather than from distinctive 'diagnostic' genotypes." Using

3348-424: The Legacy site are now under study and it seems likely that the site, which is adjacent to its main campus, will be taken over by McGill University. The Royal Victoria Hospital was established in 1893 in the historic Golden Square Mile through donations by two public-spirited Scottish immigrants, the cousins Donald Smith, 1st Lord Strathcona , and George Stephen, 1st Lord Mount Stephen . In 1887, they announced

3441-594: The Mediterranean and up the Nile into Africa. From one end of this range to the other, there is no hint of a skin color boundary, and yet the spectrum runs from the lightest in the world at the northern edge to as dark as it is possible for humans to be at the equator. In part, this is due to isolation by distance . This point called attention to a problem common to phenotype-based descriptions of races (for example, those based on hair texture and skin color): they ignore

3534-492: The Royal Victoria Hospital is part of the McGill University Health Centre . Amid the 2020 coronavirus pandemic , the hospital is currently being used as an isolation unit for homeless people who have been infected with coronavirus disease 2019 (COVID-19), as well as those awaiting test results. The hospital was previously housed in a building complex at 687 Pine Avenue on the slope of Mount Royal in

3627-579: The Tanenbaum Open Science Institute. Dr. Guy Rouleau, the current Director of The Neuro, was awarded the Canada Gairdner Wightman award in 2020, for identifying and elucidating the genetic architecture of neurological and psychiatric diseases, including ALS, autism and schizophrenia, and his leadership in the field of Open Science. The Montreal Neurological Institute is a Killam Institution, supported by

3720-489: The West came to view race as an invalid genetic or biological designation. The first to challenge the concept of race on empirical grounds were the anthropologists Franz Boas , who provided evidence of phenotypic plasticity due to environmental factors, and Ashley Montagu , who relied on evidence from genetics. E. O. Wilson then challenged the concept from the perspective of general animal systematics, and further rejected

3813-505: The anthropologist Stephen Molnar has suggested that the discordance of clines inevitably results in a multiplication of races that renders the concept itself useless. The Human Genome Project states "People who have lived in the same geographic region for many generations may have some alleles in common, but no allele will be found in all members of one population and in no members of any other." Massimo Pigliucci and Jonathan Kaplan argue that human races do exist, and that they correspond to

Montreal Neurological Institute and Hospital - Misplaced Pages Continue

3906-437: The basis for a phylogenetic tree of human races (p. 661). Biological anthropologist Jonathan Marks (2008) responded by arguing that Andreasen had misinterpreted the genetic literature: "These trees are phenetic (based on similarity), rather than cladistic (based on monophyletic descent, that is from a series of unique ancestors)." Evolutionary biologist Alan Templeton (2013) argued that multiple lines of evidence falsify

3999-596: The borough of Ville-Marie . Hospital operations moved to the new Glen site of the McGill University Health Centre on April 26, 2015, except for the McGill Reproductive Centre and the Dialysis Clinic, which remained at the original site as of 2015. Of its nine pavilions, three date from the original 1893 hospital and were designed by Henry Saxon Snell in the Scottish baronial style. The nearby Allan Memorial Institute continues to house

4092-416: The categories are chosen and constructed for pragmatic scientific reasons. In earlier work, Winther had identified "diversity partitioning" and "clustering analysis" as two separate methodologies, with distinct questions, assumptions, and protocols. Each is also associated with opposing ontological consequences vis-a-vis the metaphysics of race. Philosopher Lisa Gannett has argued that biogeographical ancestry,

4185-428: The claim that "races" were equivalent to "subspecies". Human genetic variation is predominantly within races, continuous, and complex in structure, which is inconsistent with the concept of genetic human races. According to the biological anthropologist Jonathan Marks , By the 1970s, it had become clear that (1) most human differences were cultural; (2) what was not cultural was principally polymorphic – that

4278-543: The clustering would be different. Weiss and Fullerton have noted that if one sampled only Icelanders, Mayans and Maoris, three distinct clusters would form and all other populations could be described as being clinally composed of admixtures of Maori, Icelandic and Mayan genetic materials. Kaplan and Winther therefore argue that, seen in this way, both Lewontin and Edwards are right in their arguments. They conclude that while racial groups are characterized by different allele frequencies, this does not mean that racial classification

4371-450: The consequence that the number and geographic location of any described races is highly dependent on the importance attributed to, and quantity of, the traits considered. A skin-lightening mutation, estimated to have occurred 20,000 to 50,000 years ago, partially accounts for the appearance of light skin in people who migrated out of Africa northward into what is now Europe. East Asians owe their relatively light skin to different mutations. On

4464-434: The degrees to which racial categories are biologically warranted and socially constructed. For example, in 2008, John Hartigan Jr. argued for a view of race that focused primarily on culture, but which does not ignore the potential relevance of biology or genetics. Accordingly, the racial paradigms employed in different disciplines vary in their emphasis on biological reduction as contrasted with societal construction. In

4557-459: The different species or races which inhabit it"), published in 1684. In the 18th century the differences among human groups became a focus of scientific investigation. But the scientific classification of phenotypic variation was frequently coupled with racist ideas about innate predispositions of different groups, always attributing the most desirable features to the White, European race and arranging

4650-522: The difficulty of defining a population, the clinal nature of variation, and heterogeneity across the genome (Long and Kittles 2003). In general, however, an average of 85% of statistical genetic variation exists within local populations, ≈7% is between local populations within the same continent, and ≈8% of variation occurs between large groups living on different continents. The recent African origin theory for humans would predict that in Africa there exists

4743-507: The emergency room, birthing centre, and a large modern ICU opened in 1993. A time capsule is located in the wall facing the C pavilion's elevators on the ground floor. The Hersey Pavilion, also known as the H Pavilion, was one of the first purpose-built nurses' residences in Canada. It is located on the hospital campus, and was constructed in 1905. It was designed by the well-known Montreal architects Edward & William Sutherland Maxwell . It

SECTION 50

#1732779471622

4836-676: The former, and a more liberal view on race by the latter. Today, all humans are classified as belonging to the species Homo sapiens . However, this is not the first species of homininae : the first species of genus Homo , Homo habilis , evolved in East Africa at least 2 million years ago, and members of this species populated different parts of Africa in a relatively short time. Homo erectus evolved more than 1.8 million years ago, and by 1.5 million years ago had spread throughout Europe and Asia. Virtually all physical anthropologists agree that Archaic Homo sapiens (A group including

4929-406: The frequency of one or more of the genes it possesses. It is an arbitrary matter which, and how many, gene loci we choose to consider as a significant 'constellation'". Leonard Lieberman and Rodney Kirk have pointed out that "the paramount weakness of this statement is that if one gene can distinguish races then the number of races is as numerous as the number of human couples reproducing". Moreover,

5022-815: The genetic classification of ecotypes , but that real human races do not correspond very much, if at all, to folk racial categories. In contrast, Walsh & Yun reviewed the literature in 2011 and reported: "Genetic studies using very few chromosomal loci find that genetic polymorphisms divide human populations into clusters with almost 100 percent accuracy and that they correspond to the traditional anthropological categories." Some biologists argue that racial categories correlate with biological traits (e.g. phenotype ), and that certain genetic markers have varying frequencies among human populations, some of which correspond more or less to traditional racial groupings. The distribution of genetic variants within and among human populations are impossible to describe succinctly because of

5115-560: The great American continent ". The hospital originally had 150 employees, including 14 medical doctors . Over the years, the philanthropy and business acumen of many of the residents of the Golden Square Mile - the prominent members of Montreal's English speaking community - brought the hospital global recognition as a major centre of healthcare and learning. Major contributors included James Ross , Richard Angus , Sir Vincent Meredith and Sir Montagu Allan . In 1920,

5208-437: The haplotype for beta-S hemoglobin , on the other hand, radiate out of specific geographical points in Africa. As the anthropologists Leonard Lieberman and Fatimah Linda Jackson observed, "Discordant patterns of heterogeneity falsify any description of a population as if it were genotypically or even phenotypically homogeneous". Patterns such as those seen in human physical and genetic variation as described above, have led to

5301-439: The historical process of exploration and conquest which brought Europeans into contact with groups from different continents, and of the ideology of classification and typology found in the natural sciences. The term race was often used in a general biological taxonomic sense , starting from the 19th century, to denote genetically differentiated human populations defined by phenotype. The modern concept of race emerged as

5394-521: The hope that the institute would act as a catalyst for Canadian neurology: “We dare to hope that this is the inauguration of an institute of medicine that is characteristically Canadian, the birth of a Canadian School of Neurology.” In 2016, The Neuro became the first academic institution of its kind in the world to implement in practice the principles of open science ,  when the Lawrence and Judith Tanenbaum Family Foundation donated $ 20M to establish

5487-742: The hospital became a medical research institute through the McGill University Faculty of Medicine . In 1929, Dr. Wilder Penfield established the Montreal Neurological Institute adjacent to the hospital. Among the list of medical achievements at the Royal Victoria was the first successful kidney transplant in the Commonwealth in 1958. It was achieved by a team led by nephrologist John Dossetor and surgeons Joe Luke and Ken MacKinnon. Today,

5580-455: The hospital. Stephen and Smith attached one caveat to their generous contribution to the City of Montreal: the hospital's land and its buildings must only ever be used for healing. The founders intended the Royal Vic "to be for the use of the sick and ailing without distinction of race or creed ," and when it opened in 1893 it was hailed as the "finest and most perfectly equipped (hospital) on

5673-690: The hostility between the English and Irish powerfully influenced early European thinking about the differences between people  – Europeans began to sort themselves and others into groups based on physical appearance, and to attribute to individuals belonging to these groups behaviors and capacities which were claimed to be deeply ingrained. A set of folk beliefs took hold that linked inherited physical differences between groups to inherited intellectual , behavioral , and moral qualities. Similar ideas can be found in other cultures, for example in China , where

SECTION 60

#1732779471622

5766-524: The idea of a phylogenetic tree structure to human genetic diversity, and confirm the presence of gene flow among populations. Marks, Templeton, and Cavalli-Sforza all conclude that genetics does not provide evidence of human races. Previously, anthropologists Lieberman and Jackson (1995) had also critiqued the use of cladistics to support concepts of race. They argued that "the molecular and biochemical proponents of this model explicitly use racial categories in their initial grouping of samples ". For example,

5859-521: The individuals and ideologies of one group come to perceive the members of an outgroup as both racially defined and morally inferior. As a result, racial groups possessing relatively little power often find themselves excluded or oppressed, while hegemonic individuals and institutions are charged with holding racist attitudes. Racism has led to many instances of tragedy, including slavery and genocide . In some countries, law enforcement uses race to profile suspects. This use of racial categories

5952-501: The laboratories of the institute and created an endowment fund of one million dollars in support of the scientific work of the Department of Neurology and Neurosurgery. The clinical, or hospital, part of the institute was built through donations from private individuals. The Province of Quebec and the City of Montreal agreed to be responsible for the hospital’s yearly operation. At the end of Penfield’s foundation address, he expressed

6045-422: The large and highly diverse macroethnic groups of East Indians, North Africans, and Europeans are presumptively grouped as Caucasians prior to the analysis of their DNA variation. They argued that this a priori grouping limits and skews interpretations, obscures other lineage relationships, deemphasizes the impact of more immediate clinal environmental factors on genomic diversity, and can cloud our understanding of

6138-443: The largest groups of social relevance, and these definitions can change over time. Historical race concepts have included a wide variety of schemes to divide local or worldwide populations into races and sub-races. Across the world, different organizations and societies choose to disambiguate race to different extents: The establishment of racial boundaries often involves the subjugation of groups defined as racially inferior, as in

6231-672: The last two decades of the 18th century, the theory of polygenism , the belief that different races had evolved separately in each continent and shared no common ancestor, was advocated in England by historian Edward Long and anatomist Charles White , in Germany by ethnographers Christoph Meiners and Georg Forster , and in France by Julien-Joseph Virey . In the US, Samuel George Morton , Josiah Nott and Louis Agassiz promoted this theory in

6324-565: The least diverse population they analyzed (the Surui, a population derived from New Guinea). Statistical analysis that takes this difference into account confirms previous findings that "Western-based racial classifications have no taxonomic significance". A 2002 study of random biallelic genetic loci found little to no evidence that humans were divided into distinct biological groups. In his 2003 paper, " Human Genetic Diversity: Lewontin's Fallacy ", A. W. F. Edwards argued that rather than using

6417-419: The level of alleles and allele frequencies. Nature has not created four or five distinct, nonoverlapping genetic groups of people. Another way to look at differences between populations is to measure genetic differences rather than physical differences between groups. The mid-20th-century anthropologist William C. Boyd defined race as: "A population which differs significantly from other populations in regard to

6510-623: The mid-19th century. Polygenism was popular and most widespread in the 19th century, culminating in the founding of the Anthropological Society of London (1863), which, during the period of the American Civil War, broke away from the Ethnological Society of London and its monogenic stance , their underlined difference lying, relevantly, in the so-called "Negro question": a substantial racist view by

6603-420: The more human groups they measured, the fewer discrete differences they observed among races and the more categories they had to create to classify human beings. The number of races observed expanded to the 1930s and 1950s, and eventually anthropologists concluded that there were no discrete races. Twentieth and 21st century biomedical researchers have discovered this same feature when evaluating human variation at

6696-514: The other hand, the greater the number of traits (or alleles ) considered, the more subdivisions of humanity are detected, since traits and gene frequencies do not always correspond to the same geographical location. Or as Ossorio & Duster (2005) put it: Anthropologists long ago discovered that humans' physical traits vary gradually, with groups that are close geographic neighbors being more similar than groups that are geographically separated. This pattern of variation, known as clinal variation,

6789-416: The other races along a continuum of progressively undesirable attributes. The 1735 classification of Carl Linnaeus , inventor of zoological taxonomy, divided the human species Homo sapiens into continental varieties of europaeus , asiaticus , americanus , and afer , each associated with a different humour : sanguine , melancholic , choleric , and phlegmatic , respectively. Homo sapiens europaeus

6882-400: The philosophers Jonathan Kaplan and Rasmus Winther, and the geneticist Joseph Graves , have argued that the cluster structure of genetic data is dependent on the initial hypotheses of the researcher and the influence of these hypotheses on the choice of populations to sample. When one samples continental groups, the clusters become continental, but if one had chosen other sampling patterns,

6975-408: The policing and disproportionate incarceration of certain groups. Groups of humans have always identified themselves as distinct from neighboring groups, but such differences have not always been understood to be natural, immutable and global. These features are the distinguishing features of how the concept of race is used today. In this way the idea of race as we understand it today came about during

7068-686: The possible species H. heidelbergensis , H. rhodesiensis , and H. neanderthalensis ) evolved out of African H. erectus ( sensu lato ) or H. ergaster . Anthropologists support the idea that anatomically modern humans ( Homo sapiens ) evolved in North or East Africa from an archaic human species such as H. heidelbergensis and then migrated out of Africa, mixing with and replacing H. heidelbergensis and H. neanderthalensis populations throughout Europe and Asia, and H. rhodesiensis populations in Sub-Saharan Africa (a combination of

7161-878: The previous generation had known it – as largely discrete, geographically distinct, gene pools – did not exist. The term race in biology is used with caution because it can be ambiguous. Generally, when it is used it is effectively a synonym of subspecies . (For animals, the only taxonomic unit below the species level is usually the subspecies; there are narrower infraspecific ranks in botany , and race does not correspond directly with any of them.) Traditionally, subspecies are seen as geographically isolated and genetically differentiated populations. Studies of human genetic variation show that human populations are not geographically isolated. and their genetic differences are far smaller than those among comparable subspecies. In 1978, Sewall Wright suggested that human populations that have long inhabited separated parts of

7254-475: The psychiatry department. The post-2015 future of the 122-year-old Royal Vic building is yet to be determined. McGill University has unveiled an idea to repurpose the hospital for academic purposes, but also add community and green space. , a project that opposes the wishes of the founders, lords Strathcona and Stephen. The original hospital was designed by the Scottish architect Henry Saxon Snell , who from

7347-403: The race concept, this linkage is a social distinction rather than an inherently biological one. Other dimensions of racial groupings include shared history, traditions, and language. For instance, African-American English is a language spoken by many African Americans , especially in areas of the United States where racial segregation exists. Furthermore, people often self-identify as members of

7440-523: The races. Blumenbach also noted the graded transition in appearances from one group to adjacent groups and suggested that "one variety of mankind does so sensibly pass into the other, that you cannot mark out the limits between them". From the 17th through 19th centuries, the merging of folk beliefs about group differences with scientific explanations of those differences produced what Smedley has called an " ideology of race". According to this ideology, races are primordial, natural, enduring and distinct. It

7533-592: The relationship between genes and complex traits remains poorly understood. However, Risch denied such limitations render the analysis useless: "Perhaps just using someone's actual birth year is not a very good way of measuring age. Does that mean we should throw it out? ... Any category you come up with is going to be imperfect, but that doesn't preclude you from using it or the fact that it has utility." Early human genetic cluster analysis studies were conducted with samples taken from ancestral population groups living at extreme geographic distances from each other. It

7626-411: The social sciences, theoretical frameworks such as racial formation theory and critical race theory investigate implications of race as social construction by exploring how the images, ideas and assumptions of race are expressed in everyday life. A large body of scholarship has traced the relationships between the historical, social production of race in legal and criminal language, and their effects on

7719-1092: The true patterns of affinity. In 2015, Keith Hunley, Graciela Cabana, and Jeffrey Long analyzed the Human Genome Diversity Project sample of 1,037 individuals in 52 populations, finding that diversity among non-African populations is the result of a serial founder effect process, with non-African populations as a whole nested among African populations, that "some African populations are equally related to other African populations and to non-African populations", and that "outside of Africa, regional groupings of populations are nested inside one another, and many of them are not monophyletic". Earlier research had also suggested that there has always been considerable gene flow between human populations, meaning that human population groups are not monophyletic. Rachel Caspari has argued that, since no groups currently regarded as races are monophyletic, by definition none of these groups can be clades. One crucial innovation in reconceptualizing genotypic and phenotypic variation

7812-443: The use of the race concept to classify people, and how the race concept is used, is a matter of social convention. They differ on whether the race concept remains a meaningful and useful social convention. In 1964, the biologists Paul Ehrlich and Holm pointed out cases where two or more clines are distributed discordantly – for example, melanin is distributed in a decreasing pattern from the equator north and south; frequencies for

7905-571: The world should, in general, be considered different subspecies by the criterion that most individuals of such populations can be allocated correctly by inspection. Wright argued: "It does not require a trained anthropologist to classify an array of Englishmen, West Africans, and Chinese with 100% accuracy by features, skin color, and type of hair despite so much variability within each of these groups that every individual can easily be distinguished from every other." While in practice subspecies are often defined by easily observable physical appearance, there

7998-713: Was described as active, acute, and adventurous, whereas Homo sapiens afer was said to be crafty, lazy, and careless. The 1775 treatise "The Natural Varieties of Mankind", by Johann Friedrich Blumenbach proposed five major divisions: the Caucasoid race , the Mongoloid race , the Ethiopian race (later termed Negroid ), the American Indian race , and the Malayan race , but he did not propose any hierarchy among

8091-560: Was designated a National Historic Site in 1997 in recognition of the important role the building played in the training and professionalism of nurses in Canada. The hospital had an outdoor pool and patio located between the Hersey pavilion and Allan Memorial Institute . As of 2014, the pool is closed until further notice. Race (human classification) Race is a categorization of humans based on shared physical or social qualities into groups generally viewed as distinct within

8184-400: Was formally renounced by the U.S. National Academies of Sciences, Engineering, and Medicine in 2023. Modern scholarship views racial categories as socially constructed, that is, race is not intrinsic to human beings but rather an identity created, often by socially dominant groups, to establish meaning in a social context. Different cultures define different racial groups, often focused on

8277-690: Was further argued that some groups may be the result of mixture between formerly distinct populations, but that careful study could distinguish the ancestral races that had combined to produce admixed groups. Subsequent influential classifications by Georges Buffon , Petrus Camper and Christoph Meiners all classified "Negros" as inferior to Europeans. In the United States the racial theories of Thomas Jefferson were influential. He saw Africans as inferior to Whites especially in regards to their intellect, and imbued with unnatural sexual appetites, but described Native Americans as equals to whites. In

8370-594: Was invented and rationalized lies somewhere between 1730 and 1790. According to Smedley and Marks the European concept of "race", along with many of the ideas now associated with the term, arose at the time of the scientific revolution , which introduced and privileged the study of natural kinds , and the age of European imperialism and colonization which established political relations between Europeans and peoples with distinct cultural and political traditions . As Europeans encountered people from different parts of

8463-459: Was later enlarged by the addition of new wings of the same architectural style. The H pavilion opened in 1905 as the nurses' residence). The 1920s saw the addition of the Women's and Ross Memorial pavilions. Another expansion was completed in the early 1950s giving the hospital its M and S pavilions; a portion of the original hospital was demolished to accomplish this. Lastly the C pavilion, housing

8556-457: Was the anthropologist C. Loring Brace 's observation that such variations, insofar as they are affected by natural selection , slow migration, or genetic drift , are distributed along geographic gradations or clines . For example, with respect to skin color in Europe and Africa, Brace writes: To this day, skin color grades by imperceptible means from Europe southward around the eastern end of

8649-535: Was thought that such large geographic distances would maximize the genetic variation between the groups sampled in the analysis, and thus maximize the probability of finding cluster patterns unique to each group. In light of the historically recent acceleration of human migration (and correspondingly, human gene flow) on a global scale, further studies were conducted to judge the degree to which genetic cluster analysis can pattern ancestrally identified groups as well as geographically separated groups. One such study looked at

#621378