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SNOLAB is a Canadian underground science laboratory specializing in neutrino and dark matter physics. Located 2 km below the surface in Vale 's Creighton nickel mine near Sudbury , Ontario , SNOLAB is an expansion of the existing facilities constructed for the original Sudbury Neutrino Observatory (SNO) solar neutrino experiment.

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63-662: SNOLAB is the world's deepest operational clean room facility. Although accessed through an active mine, the laboratory proper is maintained as a class-2000 cleanroom , with very low levels of dust and background radiation . SNOLAB's 2070 m (6800 feet) of overburden rock provides 6010 metre water equivalent (MWE) shielding from cosmic rays, providing a low-background environment for experiments requiring high sensitivities and extremely low counting rates. The combination of great depth and cleanliness that SNOLAB affords allows extremely rare interactions and weak processes to be studied. In addition to neutrino and dark matter physics, SNOLAB

126-700: A master's degree like MSc, MPhil, MPhys or MSci. For research-oriented careers, students work toward a doctoral degree specializing in a particular field. Fields of specialization include experimental and theoretical astrophysics , atomic physics , biological physics , chemical physics , condensed matter physics , cosmology , geophysics , gravitational physics , material science , medical physics , microelectronics , molecular physics , nuclear physics , optics , particle physics , plasma physics , quantum information science , and radiophysics . The three major employers of career physicists are academic institutions, laboratories, and private industries, with

189-448: A particle counter and microorganisms detected and counted through environmental monitoring methods . Polymer tools used in cleanrooms must be carefully determined to be chemically compatible with cleanroom processing fluids as well as ensured to generate a low level of particle generation. When cleaning, only special mops and buckets are used. Cleaning chemicals used tend to involve sticky elements to trap dust, and may need

252-471: A "tunnel" design in which there are spaces called "service chases" that serve as air plenums carrying the air from the bottom of the room to the top so that it can be recirculated and filtered at the top of the cleanroom. Cleanrooms maintain particulate-free air through the use of either HEPA or ULPA filters employing laminar or turbulent airflow principles. Laminar, or unidirectional, airflow systems direct filtered air downward or in horizontal direction in

315-554: A cleanroom in constant motion, although not all in the same direction. The rough air seeks to trap particles that may be in the air and drive them towards the floor, where they enter filters and leave the cleanroom environment. US FDA and EU have laid down stringent guidelines and limits to ensure freedom from microbial contamination in pharmaceutical products. Plenums between air handlers and fan filter units , along with sticky mats , may also be used. In addition to air filters, cleanrooms can also use ultraviolet light to disinfect

378-432: A cleanroom is usually restricted to those wearing a cleanroom suit , including the necessary machinery. In cleanrooms in which the standards of air contamination are less rigorous, the entrance to the cleanroom may not have an air shower. An anteroom (known as a "gray room") is used to put on cleanroom clothing. This practice is common in many nuclear power plants, which operate as low-grade inverse pressure cleanrooms, as

441-529: A constant stream towards filters located on walls near the cleanroom floor or through raised perforated floor panels to be recirculated. Laminar airflow systems are typically employed across 80% of a cleanroom ceiling to maintain constant air processing. Stainless steel or other non shedding materials are used to construct laminar airflow filters and hoods to prevent excess particles entering the air. Turbulent, or non-unidirectional, airflow uses both laminar airflow hoods and nonspecific velocity filters to keep air in

504-612: A conversion of part of its Cambridge, Ohio facilities in February 1961. Totalling 70,000 square feet, it was used to prepare control equipment for the Minuteman ICBM missiles. The majority of the integrated circuit manufacturing facilities in Silicon Valley were made by three companies: MicroAire, PureAire, and Key Plastics. These competitors made laminar flow units, glove boxes, cleanrooms and air showers , along with

567-480: A larger PICO-500L detector. The total size of the SNOLAB underground facilities, including utility spaces and personnel spaces, is: 46°28.3′N 81°11.2′W  /  46.4717°N 81.1867°W  / 46.4717; -81.1867  ( SNOLAB surface building ) Cleanroom A cleanroom or clean room is an engineered space that maintains a very low concentration of airborne particulates . It

630-452: A minimum, the owner must possess a three-year bachelors or equivalent degree in physics or a related field and an additional minimum of six years' experience in a physics-related activity; or an Honor or equivalent degree in physics or a related field and an additional minimum of five years' experience in a physics-related activity; or master or equivalent degree in physics or a related field and an additional minimum of three years' experience in

693-565: A physics-related activity; a Doctorate or equivalent degree in Physics or a related field; or training or experience which, in the opinion of the Council, is equivalent to any of the above. Physicists may be a member of a physical society of a country or region. Physical societies commonly publish scientific journals, organize physics conferences and award prizes for contributions to the field of physics. Some examples of physical societies are

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756-416: A professional practice examination must also be passed. An exemption can be granted to a candidate that has practiced physics for at least seven years and provide a detailed description of their professional accomplishments which clearly demonstrate that the exam is not necessary. Work experience will be considered physics-related if it uses physics directly or significantly uses the modes of thought (such as

819-432: A reduced reliance on chemical disinfectants and the extension of HVAC filter life. Some cleanrooms are kept at a positive pressure so if any leaks occur, air leaks out of the chamber instead of unfiltered air coming in. This is most typically the case in semiconductor manufacturing, where even minute amounts of particulates leaking in could contaminate the whole process, while anything leaking out would not be harmful to

882-404: A second step with light molecular weight solvents to clear. Cleanroom furniture is designed to produce a minimum of particles and is easy to clean. A cleanroom is as much a process and a meticulous culture to maintain, as it is a space as such. The greatest threat to cleanroom contamination comes from the users themselves. In the healthcare and pharmaceutical sectors, control of microorganisms

945-524: A whole. Recirculating vs. one pass cleanrooms Recirculating cleanrooms return air to the negative pressure plenum via low wall air returns. The air then is pulled by HEPA fan filter units back into the cleanroom. The air is constantly recirculating and by continuously passing through HEPA filtration removing particles from the air each time. Another advantage of this design is that air conditioning can be incorporated. One pass cleanrooms draw air from outside and pass it through HEPA fan filter units into

1008-415: Is filtered and cooled by several outdoor air handlers using progressively finer filters to exclude dust. Within, air is constantly recirculated through fan units containing high-efficiency particulate absorbing filters ( HEPA ), and/or ultra-low particulate air ( ULPA ) filters to remove internally generated contaminants. Special lighting fixtures, walls, equipment and other materials are used to minimize

1071-514: Is a scientist who specializes in the field of physics , which encompasses the interactions of matter and energy at all length and time scales in the physical universe. Physicists generally are interested in the root or ultimate causes of phenomena , and usually frame their understanding in mathematical terms. They work across a wide range of research fields , spanning all length scales: from sub-atomic and particle physics , through biological physics , to cosmological length scales encompassing

1134-624: Is a biological hazard both ways: we must not contaminate any sample return missions from other stellar bodies with terrestrial microbes, and we must not contaminate possible other ecosystems existing in other planets. Thus, even by international law, any probes we send to outer space must be sterile, and so to be handled in cleanroom conditions. Since larger cleanrooms are very sensitive controlled environments upon which multibillion-dollar industries depend, sometimes they are even fitted with numerous seismic base isolation systems to prevent costly equipment malfunction. Physicist A physicist

1197-575: Is also host to biological experiments in an underground environment. The Sudbury Neutrino Observatory was the world's deepest underground experiment since the Kolar Gold Fields experiments ended with the closing of that mine in 1992. Many research collaborations were, and still are, interested in conducting experiments in the 6000 MWE location. In 2002, funding was approved by the Canada Foundation for Innovation to expand

1260-705: Is based on an intellectual ladder of discoveries and insights from ancient times to the present. Many mathematical and physical ideas used today found their earliest expression in the work of ancient civilizations, such as the Babylonian astronomers and Egyptian engineers , the Greek philosophers of science and mathematicians such as Thales of Miletus , Euclid in Ptolemaic Egypt , Archimedes of Syracuse and Aristarchus of Samos . Roots also emerged in ancient Asian cultures such as India and China, and particularly

1323-410: Is common to all cleanrooms is strict control of airborne particulates , possibly with secondary decontamination of air, surfaces, workers entering the room, implements, chemicals, and machinery. Sometimes particulates exiting the compartment are also of concern, such as in research into dangerous viruses , or where radioactive materials are being handled. First, outside air entering a cleanroom

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1386-592: Is expressed in the following table. These concentrations will lead to large air sample volumes for classification. Sequential sampling procedure may be applied; see Annex D. Concentration limits are not applicable in this region of the table due to very high particle concentration. Sampling and statistical limitations for particles in low concentrations make classification inappropriate. Sample collection limitations for both particles in low concentrations and sizes greater than 1 μm make classification at this particle size inappropriate due to potential particle losses in

1449-412: Is important, especially microorganisms likely to be deposited into the air stream from skin shedding . Studying cleanroom microflora is of importance for microbiologists and quality control personnel to assess changes in trends. Shifts in the types of microflora may indicate deviations from the "norm" such as resistant strains or problems with cleaning practices. In assessing cleanroom microorganisms,

1512-661: Is not carried out, but room AHU is on). BS 5295 is a British Standard . BS 5295 Class 1 also requires that the greatest particle present in any sample can not exceed 5 μm. BS 5295 has been superseded, withdrawn since the year 2007 and replaced with "BS EN ISO 14644-6:2007". USP 800 is a United States standard developed by the United States Pharmacopeial Convention (USP) with an effective date of December 1, 2019. In hospitals , theatres are similar to cleanrooms for surgical patients' operations with incisions to prevent any infections for

1575-453: Is preferred. Buffed stainless steel or powder-coated mild steel sandwich partition panels and ceiling panel are used instead of iron alloys prone to rusting and then flaking . Corners like the wall to wall, wall to floor, wall to ceiling are avoided by providing coved surface , and all joints need to be sealed with epoxy sealant to avoid any deposition or generation of particles at the joints, by vibration and friction . Many cleanrooms have

1638-615: Is the Nobel Prize in Physics , awarded since 1901 by the Royal Swedish Academy of Sciences . National physical societies have many prizes and awards for professional recognition. In the case of the American Physical Society , as of 2023, there are 25 separate prizes and 33 separate awards in the field. Chartered Physicist (CPhys) is a chartered status and a professional qualification awarded by

1701-431: Is well isolated, well controlled from contamination , and actively cleansed. Such rooms are commonly needed for scientific research and in industrial production for all nanoscale processes, such as semiconductor manufacturing. A cleanroom is designed to keep everything from dust to airborne organisms or vaporised particles away from it, and so from whatever material is being handled inside it. A cleanroom can also prevent

1764-753: The Institute of Physics . It is denoted by the postnominals "CPhys". Achieving chartered status in any profession denotes to the wider community a high level of specialised subject knowledge and professional competence. According to the Institute of Physics, holders of the award of the Chartered Physicist (CPhys) demonstrate the "highest standards of professionalism, up-to-date expertise, quality and safety" along with "the capacity to undertake independent practice and exercise leadership" as well as "commitment to keep pace with advancing knowledge and with

1827-542: The International Organization for Standardization (ISO). The former applies to cleanrooms in general (see table below), the latter to cleanrooms where biocontamination may be an issue. Since the strictest standards have been achieved only for space applications, it is sometimes difficult to know whether they were achieved in vacuum or standard conditions. ISO 14644-1 defines the maximum concentration of particles per class and per particle size with

1890-548: The Islamic medieval period , which saw the development of scientific methodology emphasising experimentation , such as the work of Ibn al-Haytham (Alhazen) in the 11th century. The modern scientific worldview and the bulk of physics education can be said to flow from the scientific revolution in Europe, starting with the work of astronomer Nicolaus Copernicus leading to the physics of Galileo Galilei and Johannes Kepler in

1953-671: The humidity to such low levels that extra equipment like air ionizers are required to prevent electrostatic discharge problems. This is a particular concern within the semiconductor business, because static discharge can easily damage modern circuit designs. On the other hand, active ions in the air can harm exposed components as well. Because of this, most workers in high electronics and semiconductor facilities have to wear conductive boots while working. Low-level cleanrooms may only require special shoes, with completely smooth soles that do not track in dust or dirt. However, for safety reasons, shoe soles must not create slipping hazards. Access to

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2016-562: The universe as a whole. The field generally includes two types of physicists: experimental physicists who specialize in the observation of natural phenomena and the development and analysis of experiments, and theoretical physicists who specialize in mathematical modeling of physical systems to rationalize, explain and predict natural phenomena. Physicists can apply their knowledge towards solving practical problems or to developing new technologies (also known as applied physics or engineering physics ). The study and practice of physics

2079-558: The 1960s, Whitfield's modern cleanroom had generated more than US$ 50 billion in sales worldwide (approximately $ 483 billion today). By mid-1963, more than 200 U.S. industrial plants had such specially constructed facilities—then using the terminology “White Rooms,” “Clean Rooms,” or “Dust-Free Rooms”—including the Radio Corporation of America, McDonnell Aircraft, Hughes Aircraft, Sperry Rand, Sylvania Electric, Western Electric, Boeing, and North American Aviation. RCA began such

2142-579: The 19th century. Many physicists contributed to the development of quantum mechanics in the early-to-mid 20th century. New knowledge in the early 21st century includes a large increase in understanding physical cosmology . The broad and general study of nature, natural philosophy , was divided into several fields in the 19th century, when the concept of "science" received its modern shape. Specific categories emerged, such as "biology" and "biologist", "physics" and "physicist", "chemistry" and "chemist", among other technical fields and titles. The term physicist

2205-609: The SNO facilities into a general-purpose laboratory, and more funding was received in 2007 and 2008. Construction of the major laboratory space was completed in 2009, with the entire lab entering operation as a 'clean' space in March 2011. SNOLAB is the world's deepest underground laboratory, tied with the China Jinping Underground Laboratory since 2011. Although CJPL has more rock (2.4 km) above it,

2268-405: The air using a corona discharge . Static discharge is of particular concern in the electronics industry, where it can instantly destroy components and circuitry. Equipment inside any cleanroom is designed to generate minimal air contamination. The selection of material for the construction of a cleanroom should not generate any particulates; hence, monolithic epoxy or polyurethane floor coating

2331-463: The air. UV devices can be fitted into ceiling light fixtures and irradiate air, killing potentially infectious particulates , including 99.99 percent of airborne microbial and fungal contaminants. UV light has previously been used to clean surface contaminants in sterile environments such as hospital operating rooms. Their use in other cleanrooms may increase as equipment becomes more affordable. Potential advantages of UV-based decontamination includes

2394-399: The approach to problem-solving) developed in your education or experience as a physicist, in all cases regardless of whether the experience is in academia, industry, government, or elsewhere. Management of physics-related work qualifies, and so does appropriate graduate student work. The South African Institute of Physics also delivers a certification of Professional Physicist (Pr.Phys). At

2457-454: The chemical tanks and benches used in the "wet process" building of integrated circuits. These three companies were the pioneers of the use of Teflon for airguns, chemical pumps, scrubbers, water guns, and other devices needed for the production of integrated circuits . William (Bill) C. McElroy Jr. worked as an engineering manager, drafting room supervisor, QA/QC, and designer for all three companies, and his designs added 45 original patents to

2520-731: The cleanroom. The air then leaves through exhaust grills. The advantage of this approach is the lower cost. The disadvantages are comparatively shorter HEPA fan filter life, worse particle counts than a recirculating cleanroom, and that it cannot accommodate air conditioning. In order to minimize the carrying of particulate by a person moving into the cleanroom, staff enter and leave through airlocks (sometimes including an air shower stage) and wear protective clothing such as hoods , face masks, gloves, boots, and coveralls . Common materials such as paper , pencils , and fabrics made from natural fibers are often excluded because they shed particulates in use. Particle levels are usually tested using

2583-405: The concentration is too low or too high to be practical to test for, but such blanks should not be read as zero. Because 1 m is about 35 ft , the two standards are mostly equivalent when measuring 0.5 μm particles, although the testing standards differ. Ordinary room air is around class 1,000,000 or ISO 9. ISO 14644-1 and ISO 14698 are non-governmental standards developed by

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2646-590: The concentration of airborne particles, equal to and larger than the specified sizes, at designated sampling locations. Small numbers refer to ISO 14644-1 standards, which specify the decimal logarithm of the number of particles 0.1 μm or larger permitted per m of air. So, for example, an ISO class 5 cleanroom has at most 10 particles/m . Both FS 209E and ISO 14644-1 assume log-log relationships between particle size and particle concentration. For that reason, zero particle concentration does not exist. Some classes do not require testing some particle sizes, because

2709-534: The considered particle size which is rounded to the nearest whole number, using no more than three significant figures, N {\displaystyle {\text{N}}} is the ISO class number, D {\displaystyle {\text{D}}} is the size of the particle in μ {\displaystyle \mu } m and 0.1 is a constant expressed in μ {\displaystyle \mu } m. The result for standard particle sizes

2772-520: The designation of Professional Engineer (P. Eng.). This designation was unveiled at the CAP congress in 1999 and already more than 200 people carry this distinction. To get the certification, at minimum proof of honours bachelor or higher degree in physics or a closely related discipline must be provided. Also, the physicist must have completed, or be about to complete, three years of recent physics-related work experience after graduation. And, unless exempted,

2835-459: The early 1600s. The work on mechanics , along with a mathematical treatment of physical systems, was further developed by Christiaan Huygens and culminated in Newton's laws of motion and Newton's law of universal gravitation by the end of the 17th century. The experimental discoveries of Faraday and the theory of Maxwell's equations of electromagnetism were developmental high points during

2898-406: The effective depth for science purposes is determined by the cosmic ray muon flux, and CJPL's mountain location admits more muons from the side than SNOLAB's flat overburden . The measured muon fluxes are 0.27 μ/m²/day ( 3.1 × 10 μ/cm²/s ) at SNOLAB, and 0.305 ± 0.020 μ/m²/day ( (3.53 ± 0.23) × 10 μ/cm²/s ) at CJPL, tied to within the measurement uncertainty. (For comparison,

2961-744: The escape of materials. This is often the primary aim in hazardous biology , nuclear work , pharmaceutics and virology . Cleanrooms typically come with a cleanliness level quantified by the number of particles per cubic meter at a predetermined molecule measure. The ambient outdoor air in a typical urban area contains 35,000,000 particles for each cubic meter in the size range 0.5 μm and bigger, equivalent to an ISO 9 certified cleanroom. By comparison, an ISO 14644 -1 level 1 certified cleanroom permits no particles in that size range, and just 12 particles for each cubic meter of 0.3 μm and smaller. Semiconductor facilities often get by with level 7 or 5, while level 1 facilities are exceedingly rare. The modern cleanroom

3024-506: The following formula C N = 10 N ( 0.1 D ) 2.08 {\displaystyle {\text{C}}_{\text{N}}=10^{\text{N}}\left({\frac {0.1}{\text{D}}}\right)^{2.08}} Where C N {\displaystyle {\text{C}}_{\text{N}}} is the maximum concentration of particles in a volume of 1m 3 {\displaystyle ^{3}} of airborne particles that are equal to, or larger, than

3087-475: The generation of airborne particles. Plastic sheets can be used to restrict air turbulence if the cleanroom design is of the laminar airflow type. Air temperature and humidity levels inside a cleanroom are tightly controlled, because they affect the efficiency and means of air filtration. If a particular room requires low enough humidity to make static electricity a concern, it too will be controlled by, e.g., introducing controlled amounts of charged ions into

3150-756: The increasing expectations and requirements for which any profession must take responsibility". Chartered Physicist is considered to be equal in status to Chartered Engineer, which the IoP also awards as a member of the Engineering Council UK, and other chartered statuses in the UK. It is also considered a "regulated profession" under the European professional qualification directives. The Canadian Association of Physicists can appoint an official designation called Professional Physicist ( P. Phys. ), similar to

3213-1180: The largest employer being the last. Physicists in academia or government labs tend to have titles such as Assistants, Professors , Sr./Jr. Scientist, or postdocs . As per the American Institute of Physics , some 20% of new physics Ph.D.s holds jobs in engineering development programs, while 14% turn to computer software and about 11% are in business/education. A majority of physicists employed apply their skills and training to interdisciplinary sectors (e.g. finance ). Job titles for graduate physicists include Agricultural Scientist , Air Traffic Controller , Biophysicist , Computer Programmer , Electrical Engineer , Environmental Analyst , Geophysicist , Medical Physicist , Meteorologist , Oceanographer , Physics Teacher / Professor / Researcher , Research Scientist , Reactor Physicist , Engineering Physicist , Satellite Missions Analyst, Science Writer , Stratigrapher , Software Engineer , Systems Engineer , Microelectronics Engineer , Radar Developer, Technical Consultant, etc. The majority of Physics terminal bachelor's degree holders are employed in

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3276-411: The number and size of particles permitted per volume of air. Large numbers like "class 100" or "class 1000" refer to FED-STD-209E , and denote the number of particles of size 0.5 μm or larger permitted per cubic foot of air. The standard also allows interpolation; for example SNOLAB is maintained as a class 2000 cleanroom. A discrete, light-scattering airborne particle counter is used to determine

3339-425: The patient. In another case, severely immunocompromised patients sometimes have to be held in prolonged isolation from their surroundings, for fear of infection. At the extreme, this necessitates a cleanroom environment. The same is the case for patients carrying airborne infectious diseases, only they are handled at negative, not positive pressure. In exobiology when we seek out contact with other planets, there

3402-433: The private sector. Other fields are academia, government and military service, nonprofit entities, labs and teaching. Typical duties of physicists with master's and doctoral degrees working in their domain involve research, observation and analysis, data preparation, instrumentation, design and development of industrial or medical equipment, computing and software development, etc. The highest honor awarded to physicists

3465-467: The rate on the surface, at sea level, is about 15 million μ/m²/day.) CJPL does have the advantage of fewer radioisotopes in the surrounding rock. As of November 2019, SNOLAB hosts the following experiments : Additional planned experiments have requested laboratory space such as the next-generation nEXO , and the LEGEND-1000 searches for neutrinoless double beta decay . There are also plans for

3528-570: The sampling system. US FED-STD-209E was a United States federal standard. It was officially cancelled by the General Services Administration on November 29, 2001, but is still widely used. Current regulating bodies include ISO, USP 800, US FED STD 209E (previous standard, still used). EU GMP guidelines are more stringent than others, requiring cleanrooms to meet particle counts at operation (during manufacturing process) and at rest (when manufacturing process

3591-428: The surrounding community . The opposite is done, e.g., in the case of high-level bio-laboratories that handle dangerous bacteria or viruses; those are always held at negative pressure , with the exhaust being passed through high-efficiency filters, and further sterilizing procedures. Both are still cleanrooms because the particulate level inside is maintained within very low limits. Some cleanroom HVAC systems control

3654-416: The technology of the time. McElroy also wrote a four-page article for MicroContamination Journal, wet processing training manuals, and equipment manuals for wet processing and cleanrooms. A cleanroom is a necessity in the manufacturing of semiconductors and rechargeable batteries , the life sciences , and any other field that is highly sensitive to environmental contamination. Cleanrooms can range from

3717-478: The technology, and to be less susceptible to catastrophic failure. With such a wide area of application, not every cleanroom is the same. For example, the rooms utilized in semiconductor manufacturing need not be sterile (i.e., free of uncontrolled microbes), while the ones used in biotechnology usually must be. Vice versa, operating rooms need not be absolutely pure of nanoscale inorganic salts, such as rust , while nanotechnology absolutely requires it. What then

3780-470: The typical flora are primarily those associated with human skin ( Gram-positive cocci ), although microorganisms from other sources such as the environment ( Gram-positive rods ) and water ( Gram-negative rods ) are also detected, although in lower number. Common bacterial genera include Micrococcus , Staphylococcus , Corynebacterium , and Bacillus , and fungal genera include Aspergillus and Penicillium . Cleanrooms are classified according to

3843-401: The very small to the very large. On the one hand, a single-user laboratory can be built to cleanroom standards within several square meters, and on the other, entire manufacturing facilities can be contained within a cleanroom with factory floors covering thousands of square meters. Between the large and the small, there are also modular cleanrooms. They have been argued to lower costs of scaling

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3906-746: Was coined by William Whewell (also the originator of the term "scientist") in his 1840 book The Philosophy of the Inductive Sciences . A standard undergraduate physics curriculum consists of classical mechanics , electricity and magnetism , non-relativistic quantum mechanics , optics , statistical mechanics and thermodynamics , and laboratory experience. Physics students also need training in mathematics ( calculus , differential equations , linear algebra , complex analysis , etc.), and in computer science . Any physics-oriented career position requires at least an undergraduate degree in physics or applied physics, while career options widen with

3969-511: Was invented by American physicist Willis Whitfield . As an employee of the Sandia National Laboratories , Whitfield created the initial plans for the cleanroom in 1960. Prior to Whitfield's invention, earlier cleanrooms often had problems with particles and unpredictable airflows . Whitfield designed his cleanroom with a constant, highly filtered airflow to flush out impurities. Within a few years of its invention in

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