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Citrus depressa

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80-605: Citrus depressa ( Citrus × depressa , formerly C. pectinifera , Okinawan : シークヮーサー/シークァーサー , romanized:  shiikwaasa , Japanese : ヒラミレモン , romanized :  hirami remon or シークヮーサー , shiikwāsā , in English sometimes called shiikuwasha , shequasar , Taiwan tangerine , Okinawa lime , flat lemon , hirami lemon , or thin-skinned flat lemon , is a small citrus fruit often harvested and used when green, rich in flavonoids and native to East Asia ( Taiwan and Okinawa Islands , Japan ). Very sour, it

160-556: A distinction between the terminal form ( 終止形 ) and the attributive form ( 連体形 ), the genitive function of が ga (lost in the Shuri dialect), the nominative function of ぬ nu (cf. Japanese: の no ), as well as honorific/plain distribution of ga and nu in nominative use. Classical Japanese: 書く kaku One etymology given for the -un and -uru endings is the continuative form suffixed with uri ("to be; to exist", cf. Classical Japanese : 居り wori ): -un developed from

240-532: A family of independent clonal F1 hybrids , arising from multiple crosses between a native Ryukyu Islands mandarin species, C. ryukyuensis , and a mainland-Asian mandarin C. reticulata still found on Okinawa , designated RK3 by the researchers. This mainland parent is related to the Chinese Sun Chu Sha mandarin but has small amounts of pomello introgression that was passed on to the shiikwaasa . The mainland parent reproduces clonally, as do

320-463: A high blood β-carotene value. This can occur after a month or two of consumption of beta-carotene rich foods, such as carrots, carrot juice, tangerine juice, mangos, or in Africa, red palm oil. β-carotene dietary supplements can have the same effect. The discoloration extends to palms and soles of feet, but not to the white of the eye , which helps distinguish the condition from jaundice . Carotenodermia

400-443: A lower risk of all-cause mortality. The highest circulating beta-carotene category, compared to the lowest, correlated with a 37% reduction in the risk of all-cause mortality, while the highest dietary beta-carotene intake category, compared to the lowest, was linked to an 18% decrease in the risk of all-cause mortality. Age-related macular degeneration (AMD) represents the leading cause of irreversible blindness in elderly people. AMD

480-416: A method of dying clothes. And before alveolar and alveolo-palatal consonants, it becomes a syllabic alveolar nasal /n̩/ , as in /kaɴda/ [kan̩da] kanda "vine". In some varieties, it instead becomes a syllabic uvular nasal [ɴ̩] . Elsewhere, its exact realization remains unspecified, and it may vary depending on the first sound of the next word or morpheme. In isolation and at the end of utterances, it

560-628: A number of local dialects, the Shuri – Naha variant is generally recognized as the de facto standard, as it had been used as the official language of the Ryukyu Kingdom since the reign of King Shō Shin (1477–1526). Moreover, as the former capital of Shuri was built around the royal palace, the language used by the royal court became the regional and literary standard, which thus flourished in songs and poems written during that era. Today, most Okinawans speak Okinawan Japanese , although

640-663: A number of people still speak the Okinawan language, most often the elderly. Within Japan, Okinawan is often not seen as a language unto itself but is referred to as the Okinawan dialect ( 沖縄方言 , Okinawa hōgen ) or more specifically the Central and Southern Okinawan dialects ( 沖縄中南部諸方言 , Okinawa Chūnanbu Sho hōgen ) . Okinawan speakers are undergoing language shift as they switch to Japanese, since language use in Okinawa today

720-603: A process of glottalization of word-initial vowels. Hence, all vowels in Okinawan are predictably glottalized at the beginning of words ( */ame/ → /ʔami/ ami "rain"), save for a few exceptions. High vowel loss or assimilation following this process created a contrast with glottalized approximants and nasal consonants. Compare */uwa/ → /ʔwa/ Q wa "pig" to /wa/ wa "I", or */ine/ → /ʔɴni/ Q nni "rice plant" to */mune/ → /ɴni/ nni "chest". The moraic nasal /N/ has been posited in most descriptions of Okinawan phonology. Like Japanese, /N/ (transcribed using

800-484: A significant source of anti-oxidants. An in vitro study used antioxidant assays to determine that in 100 g (3.5 oz) of unripened Shiikwaasa peels, there is either, approximately, 225.4 mg to 294.2 mg of total phenolic compounds – composed of β‐Carotene and DPPH – which varied due to differing extraction methods. Okinawan language The Okinawan language ( 沖縄口 , ウチナーグチ , Uchināguchi , [ʔut͡ɕinaːɡut͡ɕi] ) or Central Okinawan

880-526: A stone stele at the Tamaudun mausoleum, dating back to 1501. After the invasion of Okinawa by the Shimazu clan of Satsuma in 1609, Okinawan ceased to be used in official affairs. It was replaced by standard Japanese writing and a form of Classical Chinese writing known as kanbun . Despite this change, Okinawan still continued to prosper in local literature up until the nineteenth century. Following

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960-423: A subject of a sentence Pronouns are classified the same as nouns, except that pronouns are more broad. Adverbs are classified as an independent, non-conjugating part of speech that cannot become a subject of a sentence and modifies a declinable word (用言; verbs, adverbs, adjectives) that comes after the adverb. There are two main categories to adverbs and several subcategories within each category, as shown in

1040-413: Is carotenodermia , a physically harmless condition that presents as a conspicuous orange skin tint arising from deposition of the carotenoid in the outermost layer of the epidermis . Carotenoderma , also referred to as carotenemia, is a benign and reversible medical condition where an excess of dietary carotenoids results in orange discoloration of the outermost skin layer. It is associated with

1120-574: Is a Japonic language , derived from Proto-Japonic and is therefore related to Japanese . The split between Old Japanese and the Ryukyuan languages has been estimated to have occurred as early as the 1st century AD to as late as the 12th century AD. Chinese and Japanese characters were first introduced by a Japanese missionary in 1265. Hiragana was a much more popular writing system than kanji ; thus, Okinawan poems were commonly written solely in hiragana or with little kanji. Okinawan became

1200-503: Is a Northern Ryukyuan language spoken primarily in the southern half of the island of Okinawa , as well as in the surrounding islands of Kerama , Kumejima , Tonaki , Aguni and a number of smaller peripheral islands. Central Okinawan distinguishes itself from the speech of Northern Okinawa, which is classified independently as the Kunigami language . Both languages are listed by UNESCO as endangered . Though Okinawan encompasses

1280-699: Is a flowering tree with an average height of 3–5 m (9.8–16.4 ft). The appearance is similar to calamansi . The flowers, white and about 3 cm (1.2 in) in diameter, usually bloom in April. The fruit, which appear around July, weigh about 25–60 g (0.88–2.12 oz). Unripe, the skin is a dark green, which becomes yellow during ripening. The fruits have a very low sugar content and are very sour in September, but gradually become sweeter as they ripen. Genetic analysis of shiikwaasa and other Asian island mandarin orange varieties revealed this group to be

1360-450: Is an oxidative stress, retinal disease that affects the macula, causing progressive loss of central vision. β-carotene content is confirmed in human retinal pigment epithelium. Reviews reported mixed results for observational studies, with some reporting that diets higher in β-carotene correlated with a decreased risk of AMD whereas other studies reporting no benefits. Reviews reported that for intervention trials using only β-carotene, there

1440-519: Is associated with a 6% increase in the risk of all-cause mortality , while low-dosage (<9.6 mg/day) supplementation does not have a significant effect on mortality. Research is insufficient to determine whether a minimum level of beta-carotene consumption is necessary for human health and to identify what problems might arise from insufficient beta-carotene intake. However, a 2018 meta-analysis mostly of prospective cohort studies found that both dietary and circulating beta-carotene are associated with

1520-431: Is based on a study done on rat models, and little study has been done to determine a similar correlation in humans. Dried shiikwaasa, however, is often mixed with teas for its therapeutic benefits, and can be mixed into a fruit paste with chili pepper as a garnish on grilled meats. Shiikwaasa paste has also been demonstrated to decrease plasma glucose levels in lab rats and human volunteers. High levels of flavonoids provide

1600-405: Is deeply colored, and as a hydrocarbon lacking functional groups, it is lipophilic . Plant carotenoids are the primary dietary source of provitamin A worldwide, with β-carotene as the best-known provitamin A carotenoid. Others include α-carotene and β-cryptoxanthin . Carotenoid absorption is restricted to the duodenum of the small intestine . One molecule of β-carotene can be cleaved by

1680-609: Is encoded by the BCO1 gene. A lesser amount is metabolized by the mitochondrial enzyme beta-carotene 9',10'-dioxygenase, which is encoded by the BCO2 gene. The products of this asymmetric cleavage are two beta-ionone molecules and rosafluene. BCO2 appears to be involved in preventing excessive accumulation of carotenoids; a BCO2 defect in chickens results in yellow skin color due to accumulation in subcutaneous fat. For counting dietary vitamin A intake, β-carotene may be converted either using

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1760-477: Is far from stable. Okinawans are assimilating and accenting standard Japanese due to the similarity of the two languages, the standardized and centralized education system, the media, business and social contact with mainlanders and previous attempts from Japan to suppress the native languages. Okinawan is still kept alive in popular music, tourist shows and in theaters featuring a local drama called uchinā shibai , which depict local customs and manners. Okinawan

1840-517: Is industrially made either by total synthesis (see Retinol § Industrial synthesis ) or by extraction from biological sources such as vegetables, microalgae (especially Dunaliella salina ), and genetically-engineered microbes. The synthetic path is low-cost and high-yield. Medical authorities generally recommend obtaining beta-carotene from food rather than dietary supplements. A 2013 meta-analysis of randomized controlled trials concluded that high-dosage (≥9.6 mg/day) beta-carotene supplementation

1920-403: Is largely due to the shift to Standard Japanese. Throughout history, Okinawan languages have been treated as dialects of Standard Japanese. For instance, in the 20th century, many schools used "dialect tags" to punish the students who spoke in Okinawan. Consequently, many of the remaining speakers today are choosing not to transmit their languages to younger generations due to the stigmatization of

2000-469: Is masked by chlorophyll in green leaf vegetables such as spinach , kale , sweet potato leaves, and sweet gourd leaves. The U.S. Department of Agriculture lists foods high in β-carotene content: Milligrams per 100 g Government and non-government organizations have not set a dietary requirement for β-carotene. Excess β-carotene is predominantly stored in the fat tissues of the body. The most common side effect of excessive β-carotene consumption

2080-460: Is often used as a fruit juice and has been used for alternative health practices frequently. Though the pulp has some beneficial nutrients, most health-benefitting compounds present in the fruit's peel are: Though commonly used as a fruit juice and considered an aid in metabolic health, C. depressa can potentially also aid in fat regulation. The addition of C. depressa alongside a high-fat diet has been demonstrated to decrease fat mass, though this

2160-477: Is often used like lemon or lime to garnish dishes, but is also used to make jams, or a yellow juice , which can be thinned or sweetened. Its name is occasionally translated into English as calamansi (calamondin), but strictly speaking, this is a different fruit. Shiikwaasa is primarily produced in southwest Japan, in the northern region of the main Okinawa island, along with another indigenous Japanese citrus, Tachibana (Citrus tachibana) . The two are not

2240-501: Is realized as a velar nasal [ŋ̍] . The Okinawan language was historically written using an admixture of kanji and hiragana . The hiragana syllabary is believed to have first been introduced from mainland Japan to the Ryukyu Kingdom some time during the reign of king Shunten in the early thirteenth century. It is likely that Okinawans were already in contact with hanzi (Chinese characters) due to extensive trade between

2320-579: Is reversible upon cessation of excessive intake. Consumption of greater than 30 mg/day for a prolonged period has been confirmed as leading to carotenemia. At the enterocyte cell wall, β-carotene is taken up by the membrane transporter protein scavenger receptor class B, type 1 (SCARB1). Absorbed β-carotene is then either incorporated as such into chylomicrons or first converted to retinal and then retinol, bound to retinol binding protein 2 , before being incorporated into chylomicrons. The conversion process consists of one molecule of β-carotene cleaved by

2400-411: Is specific to supplementation dose as no lung damage has been detected in those who are exposed to cigarette smoke and who ingest a physiological dose of β-carotene (6 mg), in contrast to high pharmacological dose (30 mg). . Increases in lung cancer have been attributed to the tendency of β-carotene to oxidize, yet based on the pharmacokinetics of β-carotene absorption and transport through

2480-583: Is unmotivated. Consequently, the existence of /ɸ/ must be regarded as independent of /h/ , even though the two overlap. Barring a few words that resulted from the former change, the aspirate /h/ also arose from the odd lenition of /k/ and /s/ , as well as words loaned from other dialects. Before the glide /j/ and the high vowel /i/ , it is pronounced closer to [ç] , as in Japanese. The plosive consonants /t/ and /k/ historically palatalized and affricated into /t͡ɕ/ before and occasionally following

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2560-669: The Meiji Restoration , the Japanese government abolished the domain system and formally annexed the Ryukyu Islands to Japan as the Okinawa Prefecture in 1879. To promote national unity, the government then introduced standard education and opened Japanese-language schools based on the Tokyo dialect . Students were discouraged and chastised for speaking or even writing in the local "dialect", notably through

2640-547: The phonemic and allophonic level. Namely, Okinawan retains the labialized consonants /kʷ/ and /ɡʷ/ which were lost in Late Middle Japanese , possesses a glottal stop /ʔ/ , features a voiceless bilabial fricative /ɸ/ distinct from the aspirate /h/ , and has two distinctive affricates which arose from a number of different sound processes . Additionally, Okinawan lacks the major allophones [t͡s] and [d͡z] found in Japanese, having historically fronted

2720-408: The shiikwaasa progeny of numerous independent hybridization events with distinct individual sexually-reproducing Ryukyu mandarin parents, sometimes serving as seed parent and sometimes as pollen parent. This varied origin, plus the fact that shiikwaasa grow wild and are referred to in some of the earliest poetry of the island kingdoms, suggest that the hybridizations occurred naturally. Shiikwaasa

2800-601: The Japanese government annexed Ryukyu and established Okinawa Prefecture. The prefectural office mainly consisted of people from Kagoshima Prefecture where the Satsuma Domain used to be. This caused the modernization of Okinawa as well as language shift to Japanese. As a result, Japanese became the standard language for administration, education, media, and literature. In 1902, the National Language Research Council ( 国語調査委員会 ) began

2880-474: The Northern Ryukyuan languages. Since the creation of Okinawa Prefecture, Okinawan has been labeled a dialect of Japanese as part of a policy of assimilation. Later, Japanese linguists, such as Tōjō Misao , who studied the Ryukyuan languages argued that they are indeed dialects. This is due to the misconception that Japan is a homogeneous state (one people, one language, one nation), and classifying

2960-613: The Ryukyu Kingdom was colonized by the Satsuma Domain in the south of Japan. However, Satsuma did not fully invade the Ryukyu in fear of colliding with China, which had a stronger trading relationship with the Ryukyu at the time. When Ryukyu was annexed by Japan in 1879, the majority of people on Okinawa Island spoke Okinawan. Within 10 years, the Japanese government began an assimilation policy of Japanization , where Ryukyuan languages were gradually suppressed. The education system

3040-439: The Ryukyu Kingdom and China, Japan and Korea. However, hiragana gained more widespread acceptance throughout the Ryukyu Islands, and most documents and letters were exclusively transcribed using this script, in contrast to in Japan where writing solely in hiragana was considered "women's script". The Omoro Sōshi ( おもろさうし ), a sixteenth-century compilation of songs and poetry, and a few preserved writs of appointments dating from

3120-662: The Ryukyuan group linguistically. The Yonaguni dialect is very different in phonetics from the other groups but it comes closest to the Yaeyama dialect lexically. Outside Japan, Okinawan is considered a separate language from Japanese. This was first proposed by Basil Hall Chamberlain , who compared the relationship between Okinawan and Japanese to that of the Romance languages . UNESCO has marked it as an endangered language. UNESCO listed six Okinawan language varieties as endangered languages in 2009. The endangerment of Okinawan

3200-458: The Ryukyuan languages as such would discredit this assumption. The present-day official stance of the Japanese government remains that Okinawan is a dialect, and it is common within the Japanese population for it to be called 沖縄方言 ( okinawa hōgen ) or 沖縄弁 ( okinawa-ben ) , which means "Okinawa dialect (of Japanese )". The policy of assimilation, coupled with increased interaction between Japan and Okinawa through media and economics, has led to

3280-423: The bitter taste often associated with the fruit. To make Shiikwaasa juice more palatable, sugar is commonly added excessively. However, fermentation of Citrus depressa juice has also been demonstrated to cause a significant decrease in the umami, bitterness and astringent tastes of the fruit, to aid in creating a more flavorful drink while maintaining the nutritional content of the fruit. Shiikwaasa fruits are also

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3360-451: The body to retinol (vitamin A). In foods, it has rich content in carrots , pumpkin , spinach , and sweet potato . It is used as a dietary supplement and may be prescribed to treat erythropoietic protoporphyria , an inherited condition of sunlight sensitivity. β-carotene is the most common carotenoid in plants. When used as a food coloring , it has the E number E160a. The structure

3440-407: The chart below, with major allophones presented in parentheses. The only consonant that can occur as a syllable coda is the archiphoneme |n| . Many analyses treat it as an additional phoneme /N/ , the moraic nasal , though it never contrasts with /n/ or /m/ . The consonant system of the Okinawan language is fairly similar to that of standard Japanese, but it does present a few differences on

3520-446: The chylomicrons that bypassed the liver, β-carotene is taken into cells via receptor SCARB1. Human tissues differ in expression of SCARB1, and hence β-carotene content. Examples expressed as ng/g, wet weight: liver=479, lung=226, prostate=163 and skin=26. Once taken up by peripheral tissue cells, the major usage of absorbed β-carotene is as a precursor to retinal via symmetric cleavage by the enzyme beta-carotene 15,15'-dioxygenase, which

3600-449: The development of Okinawan Japanese , which is a dialect of Japanese influenced by the Okinawan and Kunigami languages. Japanese and Okinawan only share 60% of the same vocabulary, despite both being Japonic languages. Okinawan linguist Seizen Nakasone states that the Ryukyuan languages are in fact groupings of similar dialects. As each community has its own distinct dialect, there is no "one language". Nakasone attributes this diversity to

3680-512: The effectiveness of these medications and is considered only a moderate interaction. Bile acid sequestrants and proton-pump inhibitors can decrease absorption of β-carotene. Consuming alcohol with β-carotene can decrease its ability to convert to retinol and could possibly result in hepatotoxicity . Chronic high doses of β-carotene supplementation increases the probability of lung cancer in smokers while its natural vitamer, retinol, increases lung cancer in smokers and nonsmokers. The effect

3760-410: The enterocyte cell wall, β-carotene is taken up by the membrane transporter protein scavenger receptor class B, type 1 (SCARB1). Absorbed β-carotene is then either incorporated as such into chylomicrons or first converted to retinal and then retinol, bound to retinol binding protein 2 , before being incorporated into chylomicrons. The conversion process consists of one molecule of β-carotene cleaved by

3840-471: The enzyme beta-carotene 15,15'-dioxygenase , which is encoded by the BCO1 gene, into two molecules of retinal. When plasma retinol is in the normal range the gene expression for SCARB1 and BCO1 are suppressed, creating a feedback loop that suppresses β-carotene absorption and conversion. The majority of chylomicrons are taken up by the liver, then secreted into the blood repackaged into low density lipoproteins (LDLs). From these circulating lipoproteins and

3920-471: The enzyme beta-carotene 15,15'-dioxygenase , which is encoded by the BCO1 gene, into two molecules of retinal. When plasma retinol is in the normal range the gene expression for SCARB1 and BCO1 are suppressed, creating a feedback loop that suppresses absorption and conversion. Because of these two mechanisms, high intake will not lead to hypervitaminosis A . β-Carotene can interact with medication used for lowering cholesterol . Taking them together can lower

4000-454: The first becoming a flap in word-medial position, and the second sometimes becoming a plosive in word-initial position. For example, /ɾuː/ rū "dragon" may be strengthened into /duː/ dū , and /hasidu/ hashidu "door" conversely flaps into /hasiɾu/ hashiru . The two sounds do, however, still remain distinct in a number of words and verbal constructions. Okinawan also features a distinctive glottal stop /ʔ/ that historically arose from

4080-611: The glide /j/ and the high vowel /i/ : */kiri/ → /t͡ɕiɾi/ chiri "fog", and */k(i)jora/ → /t͡ɕuɾa/ chura- "beautiful". This change preceded vowel raising, so that instances where /i/ arose from */e/ did not trigger palatalization: */ke/ → /kiː/ kī "hair". Their voiced counterparts /d/ and /ɡ/ underwent the same effect, becoming /d͡ʑ/ under such conditions: */unaɡi/ → /ʔɴnad͡ʑi/ Q nnaji "eel", and */nokoɡiri/ → /nukud͡ʑiɾi/ nukujiri "saw"; but */kaɡeɴ/ → /kaɡiɴ/ kagin "seasoning". Both /t/ and /d/ may or may not also allophonically affricate before

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4160-448: The high vowel /u/ , and /ɸ/ does not occur before the rounded vowel /o/ . This suggests that an overlap between /ɸ/ and /h/ exists, and so the contrast in front of other vowels can be denoted through labialization. However, this analysis fails to take account of the fact that Okinawan has not fully undergone the diachronic change */p/ → /ɸ/ → */h/ as in Japanese, and that the suggested clusterization and labialization into */hw/

4240-455: The intestinal enzyme β,β-carotene 15,15'-monooxygenase into two molecules of vitamin A. As part of the digestive process, food-sourced carotenoids must be separated from plant cells and incorporated into lipid-containing micelles to be bioaccessible to intestinal enterocytes . If already extracted (or synthetic) and then presented in an oil-filled dietary supplement capsule, there is greater bioavailability compared to that from foods. At

4320-515: The intestine and the lack of specific β-carotene transporters, it is unlikely that β-carotene reaches the lung of smokers in sufficient quantities. Additional research is required to understand the link between the increased risk of cancer and all-cause mortality following β-carotene supplementation. Additionally, supplemental, high-dose β-carotene may increase the risk of prostate cancer , intracerebral hemorrhage , and cardiovascular and total mortality irrespective of smoking status. β-carotene

4400-550: The isolation caused by immobility, citing the story of his mother who wanted to visit the town of Nago but never made the 25 km trip before she died of old age. The contemporary dialects in Ryukyuan language are divided into three large groups: Amami-Okinawa dialects, Miyako-Yaeyama dialects, and the Yonaguni dialect. All of them are mutually unintelligible. Amami is located in the Kagoshima prefecture but it belongs to

4480-400: The language using hiragana with kanji. In any case, no standard or consensus concerning spelling issues has ever been formalized, so discrepancies between modern literary works are common. Technically, they are not syllables, but rather morae . Each mora in Okinawan will consist of one or two kana characters. If two, then a smaller version of kana follows the normal sized kana. In each cell of

4560-572: The language. The Okinawan language is still spoken by communities of Okinawan immigrants in Brazil . The first immigrants from the island of Okinawa to Brazil landed in the Port of Santos in 1908 drawn by the hint of work and farmable land. Once in a new country and far from their homeland, they found themselves in a place where there was no prohibition of their language, allowing them to willingly speak, celebrate and preserve their speech and culture, up to

4640-674: The languages in the past. There have been several revitalization efforts made to reverse this language shift. However, Okinawan is still poorly taught in formal institutions due to the lack of support from the Okinawan Education Council: education in Okinawa is conducted exclusively in Japanese, and children do not study Okinawan as their second language at school. As a result, at least two generations of Okinawans have grown up without any proficiency in their local languages both at home and school. The Okinawan language has five vowels, all of which may be long or short, though

4720-461: The linguistic unification of Japan to Standard Japanese. This caused the linguistic stigmatization of many local varieties in Japan including Okinawan. As the discrimination accelerated, Okinawans themselves started to abandon their languages and shifted to Standard Japanese. Okinawan dialect card , similar to Welsh Not in Wales, were adopted in Okinawa, Japan. Under American administration, there

4800-411: The loss of visual acuity. These studies found no evidence of any protective effects afforded by β-carotene supplementation on preventing and slowing age-related cataract. A second meta-analysis compiled data from studies that measured diet-derived serum beta-carotene and reported a not statistically significant 10% decrease in cataract risk. High doses of β-carotene (up to 180 mg per day) may be used as

4880-469: The mid vowel /e/ , though this pronunciation is increasingly rare. Similarly, the fricative consonant /s/ palatalizes into [ɕ] before the glide /j/ and the vowel /i/ , including when /i/ historically derives from /e/ : */sekai/ → [ɕikeː] shikē "world". It may also palatalize before the vowel /e/ , especially so in the context of topicalization : [duɕi] dushi → [duɕeː] dusē or dushē "( topic ) friend". In general, sequences containing

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4960-741: The more useful retinol activity equivalent as follows: The average daily intake of β-carotene is in the range 2–7 mg, as estimated from a pooled analysis of 500,000 women living in the US, Canada, and some European countries. Beta-carotene is found in many foods and is sold as a dietary supplement . β-Carotene contributes to the orange color of many different fruits and vegetables. Vietnamese gac ( Momordica cochinchinensis Spreng.) and crude palm oil are particularly rich sources, as are yellow and orange fruits, such as cantaloupe , mangoes , pumpkin , and papayas , and orange root vegetables such as carrots and sweet potatoes . The color of β-carotene

5040-548: The newer retinol activity equivalents (RAE) or the older international unit (IU). Since 2001, the US Institute of Medicine uses retinol activity equivalents (RAE) for their Dietary Reference Intakes, defined as follows: RAE takes into account carotenoids' variable absorption and conversion to vitamin A by humans better than and replaces the older retinol equivalent (RE) (1 μg RE = 1 μg retinol, 6 μg β-carotene, or 12 μg α-carotene or β-cryptoxanthin). RE

5120-484: The official language under King Shō Shin . The Omoro Sōshi , a compilation of ancient Ryukyuan poems, was written in an early form of Okinawan, known as Old Okinawan. After Ryukyu became a vassal of Satsuma Domain , kanji gained more prominence in poetry; however, official Ryukyuan documents were written in Classical Chinese . During this time, the language gradually evolved into Modern Okinawan. In 1609,

5200-426: The only species of citrus currently growing on the island, as there have been foreign species introduced and have since been crossbred alongside Citrus depressa . Despite the varying diversity of citrus currently found in the region, only Shiikwasa and Tachibana are native to this region, originating in the Ryukyu Islands. Citrus depressa is grown in Okinawa and Taiwan. Shiikwaasa is grown in Okinawa. This flat lemon

5280-421: The palatal consonant /j/ are relatively rare and tend to exhibit depalatalization. For example, /mj/ tends to merge with /n/ ( [mjaːku] myāku → [naːku] nāku " Miyako "); */rj/ has merged into /ɾ/ and /d/ ( */rjuː/ → /ɾuː/ rū ~ /duː/ dū "dragon"); and /sj/ has mostly become /s/ ( /sjui/ shui → /sui/ sui " Shuri "). The voiced plosive /d/ and the flap /ɾ/ tend to merge, with

5360-578: The present day. Currently the Okinawan-Japanese centers and communities in the State of São Paulo are a world reference to this language helping it to stay alive. Okinawan is sometimes grouped with Kunigami as the Okinawan languages; however, not all linguists accept this grouping, some claiming that Kunigami is a dialect of Okinawan. Okinawan is also grouped with Amami (or the Amami languages) as

5440-459: The same century were written solely in Hiragana. Kanji were gradually adopted due to the growing influence of mainland Japan and to the linguistic affinity between the Okinawan and Japanese languages. However, it was mainly limited to affairs of high importance and to documents sent towards the mainland. The oldest inscription of Okinawan exemplifying its use along with Hiragana can be found on

5520-417: The short vowels /e/ and /o/ are quite rare, as they occur only in a few native Okinawan words with heavy syllables with the pattern /Ceɴ/ or /Coɴ/ , such as /m e ɴsoːɾeː/ m e nsōrē "welcome" or /t o ɴɸaː/ t o nfā . The close back vowels /u/ and /uː/ are truly rounded, rather than the compressed vowels of standard Japanese. The Okinawan language counts some 20 distinctive segments shown in

5600-422: The small capital /ɴ/ ) occupies a full mora and its precise place of articulation will vary depending on the following consonant. Before other labial consonants, it will be pronounced closer to a syllabic bilabial nasal [m̩] , as in /ʔɴma/ [ʔm̩ma] Q nma "horse". Before velar and labiovelar consonants, it will be pronounced as a syllabic velar nasal [ŋ̍] , as in /biɴɡata/ [biŋ̍ɡata] bingata ,

5680-601: The table below, the top row is the kana (hiragana to the left, katakana to the right of the dot), the middle row in rōmaji ( Hepburn romanization ), and the bottom row in IPA. Okinawan follows a subject–object–verb word order and makes large use of particles as in Japanese. Okinawan retains a number of Japonic grammatical features also found in Old Japanese but lost (or highly restricted) in Modern Japanese , such as

5760-435: The table below. あぬ Anu 夫婦 ( ふぃとぅんだー ) Beta carotene β-Carotene ( beta -carotene) is an organic , strongly colored red-orange pigment abundant in fungi, plants, and fruits. It is a member of the carotenes , which are terpenoids (isoprenoids), synthesized biochemically from eight isoprene units and thus having 40 carbons . Dietary β-carotene is a pro vitamin A compound, converting in

5840-457: The terminal form uri ; -uru developed from the attributive form uru , i.e.: A similar etymology is given for the terminal -san and attributive -saru endings for adjectives: the stem suffixed with さ sa (nominalises adjectives, i.e. high → height, hot → heat), suffixed with ari ("to be; to exist; to have", cf. Classical Japanese: 有り ari ), i.e.: Nouns are classified as independent, non-conjugating part of speech that can become

5920-493: The use of " dialect cards " ( 方言札 ). As a result, Okinawan gradually ceased to be written entirely until the American takeover in 1945. Since then, Japanese and American scholars have variously transcribed the regional language using a number of ad hoc romanization schemes or the katakana syllabary to demarcate its foreign nature with standard Japanese. Proponents of Okinawan tend to be more traditionalist and continue to write

6000-439: The vowel /u/ to /i/ after the alveolars /t d s z/ , consequently merging [t͡su] tsu into [t͡ɕi] chi , [su] su into [ɕi] shi , and both [d͡zu] dzu and [zu] zu into [d͡ʑi] ji . It also lacks /z/ as a distinctive phoneme, having merged it into /d͡ʑ/ . The bilabial fricative /ɸ/ has sometimes been transcribed as the cluster /hw/ , since, like Japanese, /h/ allophonically labializes into [ɸ] before

6080-634: Was an attempt to revive and standardize Okinawan, but this proved difficult and was shelved in favor of Japanese. General Douglas MacArthur attempted to promote Okinawan languages and culture through education. Multiple English words were introduced. After Okinawa's reversion to Japanese sovereignty, Japanese continued to be the dominant language used, and the majority of the youngest generations only speak Okinawan Japanese . There have been attempts to revive Okinawan by notable people such as Byron Fija and Seijin Noborikawa , but few native Okinawans know

6160-458: Was deduced in 1930. Isolation of β-carotene from fruits abundant in carotenoids is commonly done using column chromatography . It is industrially extracted from richer sources such as the algae Dunaliella salina . The separation of β-carotene from the mixture of other carotenoids is based on the polarity of a compound. β-Carotene is a non-polar compound, so it is separated with a non-polar solvent such as hexane . Being highly conjugated , it

6240-591: Was developed 1967 by the United Nations/ World Health Organization Food and Agriculture Organization (FAO/WHO). Another older unit of vitamin A activity is the international unit (IU). Like retinol equivalent, the international unit does not take into account carotenoid variable absorption and conversion to vitamin A by humans, as well as the more modern retinol activity equivalent. Unfortunately, food and supplement labels still generally use IU, but IU can be converted to

6320-646: Was no change to risk of developing AMD. A meta-analysis concluded that supplementation with β-carotene does not appear to decrease the risk of cancer overall, nor specific cancers including: pancreatic, colorectal, prostate, breast, melanoma, or skin cancer generally. High levels of β-carotene may increase the risk of lung cancer in current and former smokers. Results are not clear for thyroid cancer. A Cochrane review looked at supplementation of β-carotene, vitamin C, and vitamin E, independently and combined, on people to examine differences in risk of cataract , cataract extraction, progression of cataract, and slowing

6400-528: Was the heart of Japanization, where Okinawan children were taught Japanese and punished for speaking their native language, being told that their language was just a "dialect". By 1945, many Okinawans spoke Japanese, and many were bilingual. During the Battle of Okinawa , some Okinawans were killed by Japanese soldiers for speaking Okinawan. Language shift to Japanese in Ryukyu/Okinawa began in 1879 when

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