Stephen J Smith is Meritorious Investigator at the Allen Institute for Brain Science [1] and Emeritus Professor of Molecular and Cellular Physiology at Stanford University [2]. He held faculty and Howard Hughes Medical Institute positions at the Yale University School of Medicine 1980-1989. He served 1990-2014 as a Stanford Professor, teaching many courses in synaptic physiology and cellular microscopy while mentoring many students and fellows [3]. He also taught in many expert workshops and summer courses at the Woods Hole Marine Biological Laboratory and the Cold Spring Harbor Laboratory .
21-1580: (Redirected from Steve Smith ) Stephen , Steve , Stevie , or Steven Smith may refer to: Academics [ edit ] Stephen J. Smith (physiologist) , American physiologist Steven B. Smith (political scientist) (born 1951), American political scientist Stephen Smith (historian) (born 1952), British historian Sir Steve Smith (political scientist) (born 1952), British international relations theorist and university administrator Steven S. Smith (born 1953), American political scientist Stephen C. Smith (economist) (born 1955), American economist Stephen Alexander Smith (1958–2022), Canadian legal scholar Stephen Smith (gynaecologist) , British gynaecologist and university administrator Stephen D. Smith (born 1967), British Holocaust and genocide specialist Stephen C. Smith (sociologist) (born 1968), American sociologist Steven M. Smith , British plant geneticist Art and literature [ edit ] Stephen Catterson Smith (1806–1872), English-Irish portrait painter Stevie Smith (1902–1971), British poet Steven Ross Smith (born 1945), Canadian poet, writer, journalist and arts activist Steven B. Smith (poet) (born 1946), American underground poet, artist, and publisher Stephen H. Smith , American sculptor Steven C. Smith (author) , American biographer Military [ edit ] Stephen Smith (privateer) (1739–1806), American privateer and militia leader Stephen R. Smith (1836–1889), Adjutant General of
42-464: A 1985 collaborative discovery that activation of NMDA-type glutamate receptor-channels permits an influx calcium ions [7], a signal at the heart of many or most of today's synaptic plasticity models [7]. In the late 1980's, Smith's laboratory leveraged Roger Tsien 's new fluo-3-AM dye to pioneer high-frame-rate video methods for imaging calcium dynamics. In 1990, his Yale laboratory published an article demonstrating that astrocytes were capable of
63-423: A Decade of NMDA Receptor Discoveries . Neurochem Res 44 :516-530. [8] Cornell-Bell AH, Finkbeiner SM, Cooper MS, Smith SJ: Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling . Science 1990, 247 :470-473. PubMed links to 463 articles citing Cornell-Bell, et al. (1990) Perspectives on the discovery of astrocytic calcium waves: Haydon PG (2001) GLIA: listening and talking to
84-400: A form of long-distance signaling which they called "calcium waves" and which transformed much thinking about neuroglial cell biology [8]. Smith's Stanford laboratory more recently adapted William Betz ' FM 1-43 dye innovation to make the first mammalian central nervous system measurements of presynaptic function at the single-synapse [9] and single-vesicle [10] levels. The group also invented
105-1417: A powerful histology method, called "array tomography" to enable pioneering explorations of presynaptic molecular architectures [11] at single-synapse and ultrastructural levels. [1] Allen Institute Scientific Staff Profile: Stephen J Smith [2] Stanford University Faculty Profile: Stephen J Smith [3] Neurotree Profile: Stephen J Smith [4] Smith SJ, Zucker RS (1980) Aequorin response facilitation and intracellular calcium accumulation in molluscan neurones . J Physiol 300 :167-196. PubMed links to 50 articles citing to Smith and Zucker (1980) [5] Smith SJ, MacDermott AB, Weight FF (1983) Detection of intracellular Ca2+ transients in sympathetic neurones using arsenazo III . Nature 304 :350-352. A perspective on early neuronal calcium dynamics measurement progress: McBurney RN, Neering IR (1985) The measurement of changes in intracellular free calcium during action potentials in mammalian neurones . Journal of Neuroscience Methods 1985, 13:65-76. [6] Augustine GJ, Charlton MP, Smith SJ (1985) Calcium entry into voltage-clamped presynaptic terminals of squid . J Physiol 367 :143-162. [7] MacDermott AB, Mayer ML, Westbrook GL, Smith SJ, Barker JL (1986) NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones . Nature 321 :519-522. PubMed links to 301 articles citing MacDermott, et al. (1986) Perspectives on
126-755: A quantal presynaptic membrane turnover . Nature 1997 388 :478-482. PubMed links to 69 articles cited by Ryan, Reuter and Smith (1997) Perspective: Kavalali ET, Jorgensen EM (2014) Visualizing presynaptic function . Nat Neurosci 17 :10-16. [11] Micheva KD, Smith SJ (2007) Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits . Neuron 55 :25-36. PubMed links to 332 articles citing Micheva and Smith (2007) Perspectives: Koike T, Yamada H (2019) Methods for array tomography with correlative light and electron microscopy . Med Mol Morphol 52 :8-14. Wacker I, Schroeder RR (2013) Array tomography . J Microsc 252 :93-99. Amy Standen, "Touring Memory Lane Inside
147-850: Is different from Wikidata All article disambiguation pages All disambiguation pages Stephen J. Smith (physiologist) Smith earned a 1970 Reed College B.A. and a 1977 Ph.D. from the University of Washington , mentored there by Profs. Charles F. Stevens and Wolfhard Almers . Smith was a Miller Research Fellow 1977-1980 at the University of California Berkeley with Robert S. Zucker. Prof. Smith's 147 neuroscience and cell biology research publications to date are documented on his Stanford faculty profile page [2]. Some publications that have generated particularly wide and sustained attention are highlighted here, along with citation histories and perspectives from other authors. Smith's doctoral, fellowship and early faculty research pioneered
168-619: The Royal Newfoundland Regiment during World War I and was wounded at Beaumont-Hamel and at Bailleul ; he reached the rank of lieutenant. Smith served as Newfoundland trade commissioner in Portugal from 1921 to 1923. In 1925, he became fire and safety superintendent for the Newfoundland Power and Paper Company at Corner Brook ; in 1935, he was named manager for the company townsite. He was president of
189-701: The Brain" , NPR KQED-QUEST, November 18, 2010 Stephen K. Smith Stephen Kevin Smith (1894 – November 1981) was a soldier and politician in Newfoundland . He represented Port au Port in the Newfoundland House of Assembly from 1956 to 1966. The son of John Smith and Mary Hutchings, he was born in Harbour Breton and was educated at Saint Bonaventure's College . Smith served in
210-2422: The Carolina Panthers and Baltimore Ravens Steve Smith (defensive back) (born 1979), played at Oregon, drafted by the Jacksonville Jaguars Steve Smith (wide receiver, born 1985) , former Super Bowl winner with the New York Giants Association football [ edit ] Steve Smith (footballer, born 1874) (1874–1935), English international footballer Steve Smith (footballer, born 1899) (1899–1994), Scottish goalkeeper Steve Smith (footballer, born 1946) (1946–2024), English footballer and manager (Huddersfield Town) Steve Smith (footballer, born 1957) , English footballer (Birmingham City, Bradford City and Crewe Alexandra) Steven Smith (footballer, born 1985) , Scottish footballer Stephen Smith (footballer, born 1986) , English footballer Athletics [ edit ] Steve Smith (pole vaulter) (1951–2020), American pole vaulter Steve Smith (American high jumper) (born 1971), American high jumper Steve Smith (British high jumper) (born 1973), British high jumper Baseball [ edit ] Steve Smith (infielder) (born 1952), Cleveland Indians third base coach and former infielder Steve Smith (pitcher) (born 1961), American baseball coach and former pitcher Basketball [ edit ] Steve Smith (basketball coach) , American head coach for Oak Hill Academy basketball team Stephen A. Smith (born 1967), American sportswriter, NBA analyst, and talk show host Steve Smith (basketball) (born 1969), American basketball player and analyst Stevin Smith (born 1972), American basketball player Steven Smith (basketball) (born 1983), American basketball player Cricket [ edit ] Stephen Smith (cricketer) (1822–1890), English cricketer Steve Smith (cricketer, born 1961) , Australian, Australian Rebel, and Transvaal cricketer Steve Smith (cricketer) (born 1989), Australian international cricketer Ice hockey [ edit ] Steve Smith (ice hockey, born 1962) , Canadian ice hockey player, center for Colgate (NCAA) and NHL scout Steve Smith (ice hockey, born April 4, 1963) , Canadian ice hockey player, defenceman for
231-714: The Hala Strana project Politics and government [ edit ] Stephen Smith (public servant) (1887–1948), New Zealand civil servant, Resident Commissioner in the Cook Islands Stephen K. Smith (1894–1981), politician in Newfoundland, Canada Stephen Edward Smith (1927–1990), brother-in-law and campaign manager for John F. Kennedy Stephen Smith (Whitewater) (born 1949), gubernatorial aide to Bill Clinton Steve Smith (Minnesota politician) (1949–2014), American politician and member of
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#1732772802126252-1730: The Melbourne Cricket Club Steven Smith (equestrian) (born 1962), British equestrian Steve Smith (darts player) (born 1979), English darts player Stephen Smith (rugby league) , Fijian rugby league international Stephen Smith (boxer) (born 1985), British boxer Steve Smith (cyclist) (1989–2016), Canadian mountain biker Other people [ edit ] Stephen Smith (abolitionist) (1797–1873), Pennsylvanian African American abolitionist Stephen Smith (surgeon) (1823–1922), New York physician, public health organizer, and civic leader Stephen Francis Smith (1861–1928), Canadian chess master Stephen Smith (aerospace engineer) (1891–1951), pioneer of rocket mail in India Steven Smith (teamaker) (1949–2015), American tea entrepreneur Stephen G. Smith (writer) (born 1949), American journalist, writer and editor Stephen J. R. Smith , Canadian businessman Stephen Smith (journalist) (born 1956), American journalist and writer Steven Smith (astronaut) (born 1958), American technology executive and NASA astronaut Stephen Anderson Smith (born 1962), American clean energy activist Stephen Smith (died 2015), American murder victim; see Murdaugh family#Murder of Stephen Smith Characters [ edit ] Steve Smith ( American Dad! ) , in American Dad! See also [ edit ] Stefan Smith (born 1989), Antiguan footballer Steve Schmidt (disambiguation) [REDACTED] Topics referred to by
273-756: The Minnesota House of Representatives Stephen J. Smith (politician) (born 1951), American politician and member of the Wisconsin State Assembly Stephen Smith (Australian politician) (born 1955), Australian Labor Party politician, minister for defence and member for Perth Stephen Stat Smith (born 1955), American politician and member of the Massachusetts House of Representatives Steven Wayne Smith (born 1961), Texas Supreme Court justice Steven D. Smith (born 1964), member and Deputy Speaker of
294-543: The New Hampshire House of Representatives Steve Smith (Arizona politician) , member of the Arizona House of Representatives Sports [ edit ] American football [ edit ] Steve Smith (offensive lineman) (born 1944), offensive tackle & defensive end for Pittsburgh Steelers, Minnesota Vikings & Philadelphia Eagles Steve Smith (quarterback) (born 1962), player for
315-1156: The Philadelphia Flyers and the Buffalo Sabres Steve Smith (ice hockey, born April 30, 1963) , Scottish-born Canadian ice hockey player, defenceman for the Edmonton Oilers, Chicago Blackhawks, and the Calgary Flames Rugby union [ edit ] Steve Smith (rugby union, born 1951) (born 1951), English rugby union player and British Lion Steve Smith (rugby union, born 1959) , Irish rugby union player and British Lion Steve Smith (rugby union, born 1973) (born 1973), Manu Samoa & North Harbour Rugby Union player from New Zealand Stephen Smith (rugby union, born 1934) (1934–2010), English rugby union player Other sports [ edit ] Steve Smith (pool player) (born 1954), American pool player Steven Smith (Australian rules footballer) (born 1956), former Australian rules footballer and current president of
336-1088: The State of Connecticut Steven G. Smith (born 1946), United States Navy admiral Steve Smith (general) (born 1959), senior officer in the Australian Army Reserve Stephen G. Smith (general) , U.S. Army general Music and performing arts [ edit ] Steve Smith (American singer) (born 1945), American singer Steve Smith (comedian) (born 1945), Canadian comedian, best known for his alter ego Red Green W. Stephen Smith (born 1950), American voice teacher Steve Smith (drummer) (born 1954), American jazz and rock drummer Steve Smith (clown) (born 1951), American clown Stephan Said (born 1968), American singer-songwriter and activist, also known as Stephan Smith Elliott Smith (Steven Smith, 1969–2003), American musician Steve Smith (British musician) (born 1972), British singer and guitarist Steven R. Smith , American multi-instrumentalist, instrument-builder and initiator of
357-611: The University of Michigan Wolverines, 1980–1983 Steve Smith (running back) (1964–2021), player for the Los Angeles Raiders and Seattle Seahawks Steve Smith (wide receiver, born 1974) , arena football offensive specialist Steven Smith (American football coach) (born 1976), head football coach at Lincoln University in Missouri Steve Smith Sr. (born 1979), wide receiver who played with
378-644: The discovery of NMDA calcium fluxes and synaptic plasticity: Malenka RC, Bear MF (2004) LTP and LTD: an embarrassment of riches . Neuron 44:5-21. Kennedy MB (2013) Synaptic Signaling in Learning and Memory . Cold Spring Harb Perspect Biol 8 :a016824. Volianskis A, France G, Jensen MS, Bortolotto ZA, Jane DE, Collingridge GL (2015) Long-term potentiation and the role of N-methyl-D-aspartate receptors . Brain Res 1621 :5-16. Lodge D, Watkins JC, Bortolotto ZA, Jane DE, Volianskis A (2019) The 1980s: D-AP5, LTP and
399-418: The exploration of neuronal calcium dynamics . He developed an innovative theory for activity-dependent intracellular calcium dynamics then solved hard tool-building problems to test that theory empirically [4]. The new tools were then used to make the first measurements of calcium dynamics in a vertebrate neuron [5] and the first spatial mapping of a presynaptic calcium signal [6]. Those same new tools empowered
420-406: The same term This disambiguation page lists articles about people with the same name. If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=Steven_Smith&oldid=1259868402 " Category : Human name disambiguation pages Hidden categories: Short description
441-1084: The synapse . Nat Rev Neurosci 2 :185-193. Fields RD (2004) The other half of the brain . Sci Am 290 :54-61. Cotrina ML, Nedergaard M (2004) Intracellular Calcium Control Mechanisms in Glia . In Neuroglia . Edited by Kettenmann H, Ransom BR pp. 229-239. Bazargani N, Attwell D (2016) Astrocyte calcium signaling: the third wave . Nat Neurosci 19 :182-189. Jon Hamilton, " Einstein's Brain Unlocks Some Mysteries of The Mind" , NPR Morning Edition, 2 June 2010 [9] Ryan TA, Reuter H, Wendland B, Schweizer FE, Tsien RW, Smith SJ (1993) The kinetics of synaptic vesicle recycling measured at single presynaptic boutons . Neuron 11 :713-724. PubMed links to 187 articles citing Ryan, et al. (1993) Perspective: Murthy VN, Sejnowski TJ, Stevens CF (1997) Heterogeneous Release Properties of Visualized Individual Hippocampal Synapses . Neuron 18:599-612. [10] 22. Ryan TA, Reuter H, Smith SJ (1997) Optical detection of
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