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Sun Yat-sen University Cancer Center

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Sun Yat-sen University Cancer Center ( Chinese : 中山大学肿瘤防治中心; ; pinyin : Zhōngshān Dàxué Zhǒngliú Fángzhì Zhōngxīn ), abbreviated as SYSUCC, is a public hospital in Guangzhou , China. It is affiliated with Sun Yat-sen University .

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52-723: The hospital was founded in March 1964. It is a Level III Class A hospital (the highest rank in China) and the largest integrated cancer center in southern China for care, research, education and prevention. SYSUCC is ranked among the top three cancer center's in China, and is one of the best in Asia. The current President of the center is Dr. Xu Ruihua . SYSUCC is a member of the Union for International Cancer Control (UICC). The predecessor of SYSUCC

104-776: A Board of Directors with 16 directors, elected at the general assembly , act as the executive body of UICC. At its head is the President of UICC, a position currently held by Prof Anil D’Cruz from India. The organisation is managed by the CEO with a staff of some 40 employees, based in Geneva, Switzerland. The current CEO is Cary Adams, who has held this position since 2009. Member organisations, partners and other networks UICC’s more than 1,150 members include cancer societies, governmental agencies, treatment and research centres, patient support groups and professional associations from around

156-470: A biobank to collect peripheral blood, bone marrow, and tissue samples after surgery, along with other clinical information from cancer patients. They have the largest number of nasopharyngeal carcinoma samples in the world. SYSUCC is establishing a new automatic bio-sample storage retrieval system capable of storing up to 6 million samples. SYSUCC has its own Clinical Trials Center (CTC) to assist physicians and scientists to test new therapies. It includes

208-526: A National Clinical Study Center for Anticancer Drugs and a National Key Laboratory of Anti-cancer Drug Development. The CTC is CFDA certified. SYSUCC sponsors Cancer Communications, an oncology journal published in English formerly known as the Chinese Journal of Cancer. It publishes basic , clinical and translational cancer research. In 2014, it became Science Citation Indexed (SCI), it has

260-415: A broad five-year Memorandum of Understanding to carryout research on cancer diagnosis and treatment. Union for International Cancer Control The Union for International Cancer Control (previously named International Union Against Cancer ) or UICC is a non-governmental organisation with over 1,150 member organisations in more than 170 countries and territories. UICC was founded in 1933 and

312-429: A current Impact Factor (IF) of 3.822. The Editorial Board consists of members from around the world. SYSUCC has established collaborative and friendly relationships with many renowned international institutes from around the world. SYSUCC has been a sister institute with MD Anderson Cancer Center since 2003. The purpose is to create collaborative oncology research projects between MDACC and other sister institutes in

364-755: A fellowship to research heart disease therapeutics at the institute in Stockholm beginning that year, and raised questions about the "intricate relationship between the chief executive and powerful individuals". CY Leung had visited KI when in Sweden in 2014, and subsequently introduced KI president, Anders Hamsten, to Lau. The Democratic Party urged the ICAC to investigate the donation, suggesting that Leung may have abused his public position to further his son's career. The Chief Executive's Office strenuously denied suggestions of any quid pro quo, saying that "the admission of

416-417: A full, impartial and appropriate review. This scientific misconduct scandal occurred in 2014, and involved one of the institute's star surgeons, Paolo Macchiarini. Macchiarini was accused by four former colleagues and co-authors of having falsified claims in his research. After its unsuccessful effort to avoid unfavorable publicity by silencing whistleblowers, media coverage and public opinion finally forced

468-530: A journalist while making numerous false statements about his personal life; the article also questioned the accuracy of statements he had made on his CV. On 13 January 2016 – the same day that the first part of a three-part documentary about Macchiarini would air on Swedish television – Gerdin criticized the vice-chancellor's dismissal of the allegations in an interview on Swedish television. Later that day, Sveriges Television investigative TV show Dokument inifrån started airing

520-643: A statement saying that the documentary made claims of which it was unaware, and that it would consider re-opening the investigations. These concerns were echoed by the chairman of the Karolinska Institute, Lars Leijonborg, and the chairman of the Swedish Medical Association, Heidi Stensmyren, calling for an independent investigation that would also review the actions of the university and hospital management in responding to allegations of scientific misconduct. In February 2016,

572-408: A three-part series, titled "Experimenten", in which Macchiarini's work was investigated. The documentary showed Macchiarini continuing operations with the new method even after it showed little or no promise, seeming to exaggerate the health of patients following the experimental surgery despite the ultimate deaths of those patients. While Macchiarini admitted that the synthetic trachea did not work in

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624-559: Is a state-run university, which in turn means that it is subject to various laws that apply to government agencies in Sweden and similar Swedish public sector organisations, such as freedom of information legislation. By moving the actual decision making to a private body at Karolinska Institute (but not part of it), it is possible to follow the regulations for the Nobel Prize set down by the Nobel Foundation, including keeping

676-560: Is based in Geneva , Switzerland . Its member organisations feature cancer societies, governmental agencies, treatment and research centres, patient support groups and professional associations. UICC was established in Paris in 1933 following a proposal at a cancer congress in Madrid to create an international organisation that would "promote the fight against cancer through research, therapy and

728-571: Is not listed in the overall QS World University Rankings since it only ranks multi-faculty universities. However, QS does rank the Karolinska Institute in the category of Medicine, placing it as the best in Sweden, 3rd in Europe and 5th worldwide in 2020. In 2015, the QS ranked the Department of Dental Medicine 1st in the world. According to the 2021 Times Higher Education World University Rankings ,

780-535: Is one of Sweden's largest centres for training and research, accounting for 30% of the medical training and more than 40% of all academic medical and life science research conducted in Sweden. It receives around a third of Sweden's public funding for medical research. The Karolinska University Hospital , located in Solna and Huddinge, is associated with the university as a research and teaching hospital. Together they form an academic health science centre . While most of

832-532: Is only empowered to recommend laureates, while the final decision rests with the Nobel Assembly. In the early history of the Nobel Prize in Physiology or Medicine, which was first awarded in 1901, the laureates were decided upon by the entire faculty of the Karolinska Institute. The reason for creating a special body for the decisions concerning the Nobel Prize was the fact that the Karolinska Institute

884-410: Is that Leung Chuen-yan with a doctorate from Cambridge doesn't deserve his job at the Karolinska Institute... Leung the son probably could get similar junior posts in many other prestigious-sounding – at least to brand-obsessed Hongkongers – research institutes; it's not that big a deal." The institute received unfavorable attention in the 2010s for its failure to prevent the deaths of seven patients at

936-579: The Manual of Clinical Oncology with information on cancer detection, diagnosis and treatment, survivorship, special populations and palliative care. The open-access, online-only JCO Global Oncology is published in partnership with the American Society of Clinical Oncology since 2015. UICC is a non-governmental organisation governed by its member organisations, which meet in a general assembly held every two years. Between general assemblies

988-666: The State Key Laboratory of Oncology in South China (SKL), which is national recognition for the highest degree of expertise. It was founded in 2005 by the Ministry of Science and Technology in China. The laboratory is integrated into SYSUCC and its activities cover a broad spectrum in oncology from basic to translational and clinical research. There are 269 SKLs in China, 26 of them are dedicated to medicine and only seven are cancer related. In 2001, SYSUCC established

1040-731: The TNM Classification of Malignant Tumors in 1953 as the "Uniform Technique for a Clinical Classification by the TNM System", with the first pocket book edition issued in 1968. The Classification has been regularly updated and the 8th edition was published with John Wiley and Sons (Wiley) in 2017. The peer-reviewed medical journal, the International Journal of Cancer , has been the official journal of UICC since 1966 and covers topics relevant to experimental and clinical cancer research. UICC publishes with Wiley

1092-870: The World Health Organization (WHO), has consultative status with the United Nations Economic and Social Council , sits on the Governing Council of the International Agency for Research on Cancer , and works closely with the Programme of Action for Cancer Therapy (PACT) initiated by the International Atomic Energy Agency . Presidents of UICC The official mission statement of UICC reads: "UICC unites and supports

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1144-495: The cancer community to reduce the global cancer burden, to promote greater equity , and to ensure that cancer control continues to be a priority in the world health and development agenda." Its work on cancer control includes areas such as the elimination of cervical cancer , tobacco control , metastatic breast cancer , antimicrobial resistance , cancer and ageing , access to essential medicines , equity in healthcare , Universal Health Coverage and addressing cancer care in

1196-630: The Access to Oncology Medicines (ATOM) Coalition in 2022. Karolinska Institutet The Karolinska Institute ( KI ; Swedish : Karolinska Institutet ; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden and one of the foremost medical research institutes globally. The Nobel Assembly at

1248-594: The French, Spanish and Latin texts. The 1933 cancer congress in Madrid was considered the first "International Cancer Congress" and the second was held in Brussels in 1936 under the auspices of UICC. The third took place in Atlantic City, US, in 1939 before the activities of UICC were suspended due to World Word II . The fourth and fifth congresses were held in 1947 and 1950 respectively. Thereafter and until 2006,

1300-568: The Greek philosopher Socrates ' last words after he drank the poisoned cup: "Crito, we owe a cockerel to Asclepius. Do pay it. Don't forget." The Karolinska Institute offers the widest range of medical education under one roof in Sweden. Several of the programmes include clinical training or other training within the healthcare system. The close proximity of the Karolinska University Hospital and other teaching hospitals in

1352-472: The Karolinska Institute awards the Nobel Prize in Physiology or Medicine . The assembly consists of fifty professors from various medical disciplines at the university. The current vice-chancellor of Karolinska Institute is Annika Östman Wernerson , who took office in March 2023. The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm ; the main campus

1404-593: The Karolinska Institute is ranked 10th worldwide and 5th in Europe in clinical, pre-clinical and other health subjects. The 2021 U.S. News & World Report Best Global University Ranking placed KI as 11th worldwide in Psychiatry and Psychology. In 2019, the Academic Ranking of World Universities ranked the Karolinska Institute in 4th place worldwide for pharmacy, 5th for public health, 6th for nursing, and 21st for clinical medicine. The university

1456-461: The Karolinska Institute published a review of Macchiarini's CV that identified discrepancies. In March 2016. the institute terminated Macchiarini's contract. In October 2016, the BBC broadcast a three-part Storyville documentary, Fatal Experiments: The Downfall of a Supersurgeon , directed by Bosse Lindquist and based on the earlier Swedish programmes about Macchiarini. After the special aired,

1508-472: The Karolinska Institute requested Sweden's national scientific review board to review six of Macchiarini's publications about the procedures. The board published its findings in October 2017, and concluded that all six demonstrated scientific misconduct, in particular by failing to report the surgical complications and deaths that occurred after the interventions; and that one of the articles falsely claimed that

1560-488: The Karolinska Institute, appointed by the faculty of the institute, and is a private organisation which is formally not part of the Karolinska Institute. The main work involved in collecting nominations and screening nominees is performed by the Nobel Committee at the Karolinska Institute, which has five members. The Nobel Committee, which consists of members appointed by the Nobel Assembly for a period of three years,

1612-413: The Stockholm area thus plays an important role during the education. Approximately 6,000 full-time students are taking educational and single subject courses at Bachelor and Master levels at the Karolinska Institute. Annually, 20 upper high school students from all over Sweden get selected to attend Karolinska's 7-week long biomedical summer research school, informally named "SoFo". The Karolinska Institute

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1664-507: The [Chief Executive's] son to post-doctoral research at KI is an independent decision by KI having regard to his professional standards. He [the son] plays no role and does not hold any position at the [proposed] Ming Wai Lau Center for Regenerative Medicine." This accusation has also been questioned by the South China Morning Post ' s Canadian-based pro-Beijing and pro-government opinion columnist, Alex Lo: "The insinuation

1716-585: The confidentiality of all documents and proceedings for a minimum of 50 years. Also, the legal possibility of contesting the decisions in e.g. administrative courts is removed. The other two Nobel Prize-awarding bodies in Sweden, the Royal Swedish Academy of Sciences and the Swedish Academy, are legally private organisations (although enjoying royal patronage), and have therefore not had to make any special arrangements to be able to follow

1768-482: The current state, he did not agree that trying it on several additional patients without further testing had been inappropriate. Allegations were also made that patients' medical conditions both before and after the operations, as reported in academic papers, were inconsistent with patient records. Macchiarini also claimed that the synthetic trachea had been tested on animals before using it on humans, something that could not be verified. On 28 January, Karolinska issued

1820-503: The development of social activities." The organisation was given the Latin name Unio Internationalis Contra Cancrum , hence the acronym UICC, and the first General Assembly took place in Paris on 4 May 1935, with representatives from 67 national cancer organisations and 43 countries. The English name was changed in 2010 to its current name, Union for International Cancer Control so that the "UICC" acronym would be consistent with that for

1872-742: The fight against cancer. In 2004, SYSUCC set up a joint laboratory with the Karolinska Institutet of Sweden for research in immunotherapy, molecular virology and oncological epidemiology. SYSUCC signed a Memorandum of Understanding (MoU) with the UK's University of Warwick in 2015, creating a partnership in cancer diagnosis, care and research. SYSUCC and the University of Warwick are exploring opportunities in regards to digital pathology, nursing, and anti-cancer drug research. In 2017, SYSUCC and Fred Hutchinson Cancer Research Center signed

1924-403: The findings and a rebuttal provided by Macchiarini, vice-chancellor of Karolinska Institute Anders Hamsten found that Macchiarini had acted "without due care" but had not committed misconduct. The journal The Lancet , which published Macchiarini's work, also published an article defending Macchiarini. On 5 January 2016, the magazine Vanity Fair published a story about Macchiarini romancing

1976-409: The hands of one of their star surgeons, Paolo Macchiarini , who was ultimately found to have repeatedly falsified medical data in order to perform experimental surgeries that were unsuccessful and led to the deaths of the patients, where diseased tracheas were replaced with prosthetic implants. The institute was accused of engaging in targeted retribution against the whistleblowers rather than conducting

2028-461: The hospital. Gerdin's report was released by Karolinska in May 2015. Gerdin found that Macchiarini had committed research misconduct in seven out of seven papers: The findings showed he had not obtained ethical approval for the some of his operations (as claimed), and had misrepresented the result of some of those operations, as well as work he had done with animals. In August 2015, after considering

2080-463: The institute to act. In April 2015, the ethics committee of the institute issued a response to one set of allegations with regard to research ethics and peer review at the Lancet , and found them to be groundless. The Karolinska Institute later appointed an external expert, Bengt Gerdin, to review the charges, comparing the results reported by Macchiarini and his collaborators to the medical record of

2132-479: The international cancer congress – later named World Cancer Congress – and UICC’s General Assembly were held every four years; since 2006 they have been held every two years. The 2020 World Cancer Congress that was due to be held in Oman had to be called off because of the coronavirus pandemic. The organisation moved to Geneva in 1948 to be close to the global health organisations. Today, UICC has official relations with

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2184-663: The leadership of Liang Boqiang. In 1966, the name of the hospital was changed to the Affiliated Cancer Hospital of Sun Yat-sen Medical College. The name was later changed again in 1985, to the Affiliated Cancer Hospital of Sun Yat-sen Medical University. Twenty-three years after both their respective establishments, in 1987, the Cancer Hospital and the Cancer Institute merged under the name Sun Yat-sen Medical University Cancer Center. The name

2236-569: The medical programs are taught in Swedish, the bulk of the PhD projects are conducted in English. The institute's name is a reference to the Caroleans . The rod of Asclepius is named after the god of medicine, Aesculapius or Asclepius. This ancient god was the son of Apollo and was generally accompanied by a snake. Over time, the snake became coiled around the staff borne by the god. The snake bowl

2288-456: The procedure had been approved by an ethics committee , when this had not happened. The board called for all six of the papers to be retracted. It also reported that all of the papers' co-authors had committed scientific misconduct as well. The Nobel Assembly at the Karolinska Institute is a body at the Karolinska Institute that awards the Nobel Prize in Physiology or Medicine. The Nobel Assembly consists of fifty professors in medical subjects at

2340-420: The time of the coronavirus pandemic. UICC convenes the cancer community at events (World Cancer Congress, World Cancer Leaders’ Summit), organises thematic webinars , provides training, fellowships and grants , and advocates for effective cancer control. It is also behind World Cancer Day , an official international awareness day marked every year on February 4 . Scientific publications UICC published

2392-780: The world. UICC also works with over 60 partners, including other health organisations, foundations and private sector companies committed to reducing the global cancer burden. In addition, UICC is a founding member of the NCD Alliance , the McCabe Centre for Law & Cancer, and the International Cancer Control Partnership UICC established the City Cancer Challenge Foundation in January 2019 and

2444-528: Was a founding member of the League of European Research Universities . In February 2015, the KI announced it had received a record $ 50 million donation from Lau Ming-wai, who chairs Hong Kong property developer Chinese Estates Holdings , and would establish a research centre in the city. Within a few days, Next Magazine revealed that Chuen-yan – son of Hong Kong Chief Executive CY Leung – had recently been awarded

2496-605: Was a professor and head of the radiology department since 1928, to chair the radiology department at Lingang University . Since the early 1950s and with the help of Ke Lin, the Dean of the Zhongshan Medical School, they later established the Tumor Hospital in South China. The hospital opened its doors in March 1964 under the leadership of Hsieh Chih Kuang. A few days later a Cancer Institute was opened under

2548-411: Was originally depicted together with Asclepius' daughter, the virgin goddess of health Hygieia or Hygiea. The snake ate from her bowl, which was considered to bring good fortune. There is nothing to support the notion that the snake would secrete its venom into the bowl. The cockerel symbolises new life and was sacrificed to Asclepius by those who had recovered from illness. This is the meaning behind

2600-555: Was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg , Huddinge , south of Stockholm. The institute also has a Centre for Reparative Medicine, consisting of two nodes, one in Stockholm and one in Hong Kong. The Karolinska Institute is Sweden's third oldest medical school, after Uppsala University (founded in 1477) and Lund University (founded in 1666). It

2652-468: Was simplified in 2001 to Sun Yat-sen University Cancer Center. According to the 2018 Nature Index report for global healthcare , the achievements of SYSUCC's active research environment were number 81 among the top 100 medical institutes in the world. "The Nature Index is a freely accessible database of author affiliation information collated from research articles published in an independently selected group of high-quality science journals." SYSUCC hosts

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2704-416: Was the Tumor Hospital in South China. The founders were Professor Hsieh Chih Kuang ( 谢志光 ), a pioneer of clinical radiology and the founding father of radiation oncology in China, and Professor Liang Boqiang ( 梁伯强 ), the originator of modern pathology in China. In 1948, Hsieh Chih Kuang (Medical Doctor from University of Connecticut 1922) was recruited from PUMC ( Peking Union Medical College ), where he

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