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Aristolochia

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108-453: Over 500, see text Hocquartia Dum. Holostylis Duch., Ann. Sci. Nat., Bot. sér. 4, 2: 33, t. 5. 1854. Isotrema Raf. (disputed) Aristolochia ( English: / ə ˌ r ɪ s t ə ˈ l oʊ k i ə / ) is a large plant genus with over 500 species that is the type genus of the family Aristolochiaceae . Its members are commonly known as birthwort , pipevine or Dutchman's pipe and are widespread and occur in

216-502: A cut reed that were bandaged around the injury. Many Greek doctors came to Rome. Many of them strongly believed in achieving the right balance of the four humors and restoring the natural heat of patients. Around 200 BC many wealthy families in Rome had personal Greek physicians. By around 50 BC, it was more common than not to have a Greek physician. Physicians were also more inclined to study anthropology, biology and physiology because of

324-440: A different tradition, that the plant was named for the otherwise unknown individual with the common Greek name Aristolochos, who had learned from a dream that it was an antidote for snake bites. Many species of Aristolochia are eaten by the caterpillar larvae of swallowtail butterflies , thus making themselves unpalatable to most predators . Lepidoptera feeding on pipevines include: Choreutidae Papilionidae In Australia

432-461: A group of veterinarians , administrators, and wound dressers, known as veteranarii , optio valetudinarii , and capsarii respectively. Other hospitals were designed to care for slaves . Slave valetudinaria were of lower quality then the military hospitals, with less equipment and poorer doctors. Roman writers compared these institutions to veterinary care, and equated the treatment these hospitals gave to barbarity . A standard valetudinarium

540-420: A medical crisis to occur. Galenic medical texts embody the written medical tradition of classical antiquity. Little written word has survived from before that era. The volume of Galen's extant written works, however, is nearly 350 – far surpassing any other writer of the period. Prior to Galen, much of medical knowledge survived through word of mouth. The tradition of transmission and translation originated with

648-488: A medicine chest with pyxides inside, which contained medicinal tablets or pills full of a number of zinc compounds, as well as iron oxide, starch, beeswax, pine resin and other plant-derived materials, all probably served as some sort of eye medicine or eyewash. A physician's overall goal was to help those afflicted by disease or injury as best as they could; the physician's credibility rested on their successful cures. Of course they could not reliably cure ailments; sometimes

756-572: A millennium. By the age of 20, he had served for four years in the local temple as a therapeutes ("attendant" or "associate") of Asclepius . Although Galen studied the human body, dissection of human corpses was against Roman law , so instead he used pigs, apes, sheep, goats, and other animals. Through studying animal dissections, Galen applied his animal anatomy findings and developed a theory of human anatomy. Galen moved to Rome in 162. There he lectured, wrote extensively, and performed public demonstrations of his anatomical knowledge. He soon gained

864-504: A physician "must be skilled at reasoning about the problems presented to him, must understand the nature and function of the body within the physician world, and must practice temperance and despise all money". The ideal physician treats both the poor and elite fairly and is a student of all that affects health. Galen thought that eleven years of study was an adequate amount of time to make a competent physician. He references Hippocrates throughout his writings, saying that Hippocratic literature

972-551: A protective response. The first such plant receptors were identified in rice and in Arabidopsis thaliana . Plants have some of the largest genomes of all organisms. The largest plant genome (in terms of gene number) is that of wheat ( Triticum aestivum ), predicted to encode ≈94,000 genes and thus almost 5 times as many as the human genome . The first plant genome sequenced was that of Arabidopsis thaliana which encodes about 25,500 genes. In terms of sheer DNA sequence,

1080-420: A range of physical and biotic stresses which cause DNA damage , but they can tolerate and repair much of this damage. Plants reproduce to generate offspring, whether sexually , involving gametes , or asexually , involving ordinary growth. Many plants use both mechanisms. When reproducing sexually, plants have complex lifecycles involving alternation of generations . One generation, the sporophyte , which

1188-563: A reputation as an experienced physician, attracting to his practice a large number of patients. Among them was the consul Flavius Boethius , who introduced him to the imperial court, where he became a physician to Emperor Marcus Aurelius . Despite being a member of the court, Galen reputedly shunned Latin , preferring to speak and write in his native Greek . He treated Roman emperors Lucius Verus , Commodus , and Septimius Severus . In 166, Galen returned to Pergamon, but went back to Rome for good in 169. Galen followed Hippocrates ' theory of

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1296-518: A select number of public physicians per region. Greek symbols and gods greatly influenced ancient Roman medicine. The caduceus , a staff wrapped with two snakes, was originally associated with Hermes , the Greek god of commerce. This symbol later became associated with the Roman god Mercury . Later, in the 7th century, the caduceus became associated with health and medicine due to its association with

1404-435: A series of end-stage renal disease cases was reported from Belgium associated with a weight loss treatment, where Stephania tetrandra in a herbal preparation was suspected of being replaced with Aristolochia fangchi . More than 105 patients were identified with nephropathy following the ingestion of this preparation from the same clinic from 1990 to 1992. Many required renal transplantation or dialysis . Aristolochia

1512-509: A small cluster of tents and fortresses dedicated to wounded soldiers. The original hospitals were built along major roads, and soon became part of Roman fort architecture . They were usually placed near the outer wall in a quiet part of the fortification. The earliest known Roman hospitals of the Roman Empire were built in the 1st and 2nd centuries AD, in the reign of the emperor Trajan . The Roman military established these hospitals, as

1620-450: A temple of Asclepius , the Roman god of medicine, for healing. Surgery was typically used as a last resort because of the risks involved. When surgery did happen though, it was usually limited to the surface of the body because doctors recognized that injuries regarding the body's most important physiological functions (brain, heart, spine, etc.) could not usually be treated. There were

1728-399: A treatment for many ailments ranging from constipation to deafness. He would issue precise instructions on how to prepare the cabbage for patients with specific ailments. He also used cabbage in liquid form. For example, a mixture of cabbage, water, and wine would be embedded in a deaf man's ear to allow his hearing to be restored. Cato would treat fractured or broken appendages with two ends of

1836-415: A variety of surgical tools in ancient Rome. For example, bone levers were tools used to remove diseased bone tissue from the skull and to remove foreign objects (such as a weapon) from a bone. The ancient Romans were capable of performing techniques like cataract surgery and caesarean sections . They also could perform more outdated procedures such as bloodletting . Ancient Roman surgery was developed in

1944-404: Is diploid (with 2 sets of chromosomes ), gives rise to the next generation, the gametophyte , which is haploid (with one set of chromosomes). Some plants also reproduce asexually via spores . In some non-flowering plants such as mosses, the sexual gametophyte forms most of the visible plant. In seed plants (gymnosperms and flowering plants), the sporophyte forms most of the visible plant, and

2052-467: Is a cause of Balkan nephropathy , a severe renal disease occurring in parts of southeast Europe . In 2001 the UK government banned the sale, supply and importation of any medicinal product consisting of or containing a plant of the genus Aristolochia. Several other plant species that do not cause themselves kidney poisoning, but which were commonly substituted with Aristolochia in the remedies, were prohibited in

2160-639: Is a component of some Chinese herbal medicines . Aristolochia has been shown to be both a potent carcinogen and kidney toxin. Herbal compounds containing Aristolochia are classified as a Group 1 carcinogen by the International Agency for Research on Cancer . Epidemiological and laboratory studies have identified Aristolochia to be a dangerous kidney toxin; Aristolochia has been shown to be associated with more than 100 cases of kidney failure. Furthermore, it appears as if contamination of grain with European birthwort ( A. clematitis )

2268-586: Is a sexually transmitted disease in which some subtypes of it can cause trachoma, which is a major source of cause for severe sight impairment, if not blindness. Colostrum was a reasonably effective treatment for Chlamydia in the absence of other antibiotics. Dream interpretation was another avenue for treatment of illnesses by physicians. Often the interpretations of a patient's dreams would actually determine what treatment they received. A Hippocratic work titled Regimen in Acute Diseases details much of

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2376-547: Is a similar process. Structures such as runners enable plants to grow to cover an area, forming a clone . Many plants grow food storage structures such as tubers or bulbs which may each develop into a new plant. Some non-flowering plants, such as many liverworts, mosses and some clubmosses, along with a few flowering plants, grow small clumps of cells called gemmae which can detach and grow. Plants use pattern-recognition receptors to recognize pathogens such as bacteria that cause plant diseases. This recognition triggers

2484-399: Is actually a rather effective treatment due to the benefits associated with it. For example, the use of colostrum has been shown to prevent the growth of Staphylococcus bacteria, which are a known cause of several types of infection. Colostrum is about half as effective as some antibiotics prescribed to patients today. Colostrum is also effective against the bacterium chlamydia . Chlamydia

2592-408: Is attributed to Galen, who coupled the four qualities of cold, heat, dry, and wet with the four main fluids of the body, would remain in health care for another millennia or so. Galen wrote a short essay called "The Best Doctor Is Also A Philosopher", where he writes that a physician needs to be knowledgeable about not just the physical, but additionally logical and ethical philosophy. He writes that

2700-536: Is colloquially known as "worm killer" due to supposed antihelminthic activity. Aristolochia taxa have also been used as reptile repellents. A. serpentaria (Virginia snakeroot) is thus named because the root was used to treat snakebite, as "so offensive to these reptiles, that they not only avoid the places where it grows, but even flee from the traveler who carries a piece of it in his hand". A. pfeiferi , A. rugosa , and A. trilobata are also used in folk medicine to treat snakebites. In 1993,

2808-495: Is extant (first published in 1838, later by V. Rose , in 1882, with a 6th-century Latin translation by Muscio , a physician of the same school). He accounts for the internal difficulties that could arise during labor from both the mother and the fetus. He also did work with fractures, surgery, and embryology. The Roman medical system saw the establishment of the first hospitals; these were reserved for slaves and soldiers. Physicians were assigned to follow armies or ships, tending to

2916-451: Is found to be cut he says treatment is unlikely to be successful but suggests suturing the intestine. Treatment of abdominal wounds should occur quickly and for fear exposed intestines would dry out. Celsus suggests adding water to the intestines to prevent this. The Romans also knew about the delicate care needed for such complex wounds. Assistants with surgical hooks were used to stitch up large abdominal wounds. They were used to help separate

3024-527: Is four to six locular. These flowers have a specialized pollination mechanism. The plants are aromatic and their strong scent attracts insects. The inner part of the perianth tube is covered with hairs, acting as a fly-trap. These hairs then wither to release the fly, covered with pollen. The fruit is dehiscent capsule with many endospermic seeds. The common names Dutchman's pipe and pipevine (e.g. common pipevine, A. durior ) are an allusion to old-fashioned meerschaum pipes at one time common in

3132-496: Is known as botany , a branch of biology . All living things were traditionally placed into one of two groups, plants and animals . This classification dates from Aristotle (384–322 BC), who distinguished different levels of beings in his biology , based on whether living things had a "sensitive soul" or like plants only a "vegetative soul". Theophrastus , Aristotle's student, continued his work in plant taxonomy and classification. Much later, Linnaeus (1707–1778) created

3240-447: Is known he lived during the reigns of Augustus and Tiberius . The only surviving work from his larger encyclopaedia is De Medicina . This work contains eight volumes, two of which are on surgery. De Medicina provides some of the best accounts of Roman medicine during his time. Its contents proved to be valuable even into the 15th century after Pope Nicolas V rediscovered it, becoming the first medical book to be published in 1478. It

3348-507: Is still debated if he practiced medicine himself or just compiled the works of the time, much of it from Greek sources. This is important because at the time Greeks were looked down upon by the Romans and thus so was the work of doctors. In his book he discussed the two different schools of thought at the time relating to medicine he calls "Empirics" and "Dogmatics". Empirics followed empirical observation while Dogmatics needed to understand

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3456-581: Is the basis for physicians' conduct and treatments. The writings of Galen survived longer than the writings of any other medical researchers of antiquity. Galen also wrote an astrological doctrine, De diebus decretorus ( Critical Days Book III), in which he describes the importance of astrology in prognosis and diagnosis. Asclepiades studied to be a physician in Alexandria and practiced medicine in Asia Minor as well as Greece before he moved to Rome in

3564-817: The De materia medica , an encyclopaedia written by Pedanius Dioscorides between 50 and 70 AD. Dioscorides was a Roman physician of Greek descent. The manuscripts classified and illustrated over 1000 substances and their uses. De materia medica influenced medical knowledge for centuries, due to its dissemination and translation into Greek, Arabic, and Latin. Galen wrote in Greek, but Arabic and Syriac translations survived as well. He referenced and challenged written works by Hippocratic physicians and authors, which gave insight into other popular medical philosophies. Herophilus , known for his texts on anatomy through dissection, and Erasistratus , also known for anatomy and physiology, survive through Galenic reference. Galen also referenced

3672-627: The Antarctic flora , consisting of algae, mosses, liverworts, lichens, and just two flowering plants, have adapted to the prevailing conditions on that southern continent. Plants are often the dominant physical and structural component of the habitats where they occur. Many of the Earth's biomes are named for the type of vegetation because plants are the dominant organisms in those biomes, such as grassland , savanna , and tropical rainforest . Medicine in ancient Rome Medicine in ancient Rome

3780-581: The Azoth , the alchemical "universal solvent". Cato the Elder despised every aspect of Greek society the Romans decided to mimic including sculptures, literature and medicine. He regarded the welcome given in Rome to Greek medicine and physicians as a major threat. In Rome, before there were doctors, the paterfamilias (head of the family) was responsible for treating the sick. Cato the Elder himself examined those who lived near him, often prescribing cabbage as

3888-706: The Cretaceous so rapid that Darwin called it an " abominable mystery ". Conifers diversified from the Late Triassic onwards, and became a dominant part of floras in the Jurassic . In 2019, a phylogeny based on genomes and transcriptomes from 1,153 plant species was proposed. The placing of algal groups is supported by phylogenies based on genomes from the Mesostigmatophyceae and Chlorokybophyceae that have since been sequenced. Both

3996-784: The Suda , he trained at the Alexandria School of Medicine and practiced in Rome. Soranus was a part of the Methodic school of Asclepiades, which fostered the ideals of the Hippocratic doctrine. He was the chief representative of the Methodic school of physicians. Soranus's most notable work was his book gynaecology, in which he discussed many topics that are considered modern ideas such as birth control, pregnancy, midwife's duties, and post-childbirth care. His treatise Gynaecology

4104-457: The carpels or ovaries , which develop into fruits that contain seeds . Fruits may be dispersed whole, or they may split open and the seeds dispersed individually. Plants reproduce asexually by growing any of a wide variety of structures capable of growing into new plants. At the simplest, plants such as mosses or liverworts may be broken into pieces, each of which may regrow into whole plants. The propagation of flowering plants by cuttings

4212-623: The eukaryotes that form the kingdom Plantae ; they are predominantly photosynthetic . This means that they obtain their energy from sunlight , using chloroplasts derived from endosymbiosis with cyanobacteria to produce sugars from carbon dioxide and water, using the green pigment chlorophyll . Exceptions are parasitic plants that have lost the genes for chlorophyll and photosynthesis, and obtain their energy from other plants or fungi. Most plants are multicellular , except for some green algae. Historically, as in Aristotle's biology ,

4320-441: The four humours , believing that one's health depended on the balance between the four main fluids of the body (blood, yellow bile, black bile, and phlegm). Food was believed to be the initial object that allowed the stabilization of these humours. By contrast, drugs, venesection , cautery and surgery were drastic and were to be used only when diet and regimen could no longer help. The survival and amendment of Hippocratic medicine

4428-505: The invasive Aristolochia littoralis is fatal to the caterpillars of Ornithoptera euphorion and O. richmondia and threatens to displace their proper host, A. tagala . The species Aristolochia clematitis was highly regarded as a medicinal plant since the ancient Egyptians , Greeks and Romans , and on until the Early Modern era; it also plays a role in traditional Chinese medicine . Due to its resemblance to

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4536-400: The military . Access to these hospitals was likely an important perk of military service. The care these institutions provided was likely highly professional for the time, and they were capable of holding up to 200 patients. Celsus describes these hospitals as large and staffed by "over-worked doctors". These over-worked doctors were known as the medici . Alongside the medici , there was

4644-1003: The "chlorophyte algae" and the "streptophyte algae" are treated as paraphyletic (vertical bars beside phylogenetic tree diagram) in this analysis, as the land plants arose from within those groups. The classification of Bryophyta is supported both by Puttick et al. 2018, and by phylogenies involving the hornwort genomes that have also since been sequenced. Rhodophyta [REDACTED] Glaucophyta [REDACTED] Chlorophyta [REDACTED] Prasinococcales   Mesostigmatophyceae Chlorokybophyceae Spirotaenia [REDACTED] Klebsormidiales [REDACTED] Chara [REDACTED] Coleochaetales [REDACTED] Hornworts [REDACTED] Liverworts [REDACTED] Mosses [REDACTED] Lycophytes [REDACTED] [REDACTED] Gymnosperms [REDACTED] Angiosperms [REDACTED] Plant cells have distinctive features that other eukaryotic cells (such as those of animals) lack. These include

4752-417: The 1st century BC. His knowledge of medicine allowed him to flourish as a physician. Asclepiades was a leading physician in Rome and was a close friend of Cicero. He developed his own version of the molecular structure of the human body. Asclepiades' atomic model contained multi-shaped atoms that passed through bodily pores. These atoms were either round, square, triangular. Asclepiades noted that as long as

4860-518: The 2005 Pharmacopoeia of the People's Republic of China . In traditional Chinese medicine Aristolochia species are used for certain forms of acute arthritis and edema . Despite the toxic properties of aristolochic acid, naturopaths claim that a decoction of birthwort stimulates the production and increases the activity of white blood cells , or that pipevines contain a disinfectant which assists in wound healing . Also, Aristolochia bracteolata

4968-548: The 2nd century from Greek techniques by doctors such as Galen . Correct diet was seen as essential to healthy living. Food was perceived to have a healing effect or a causative effect on disease, determined by its impact on the humors; as well as preventing disease. Some of these foods included rice, chic peas, and olives, which were widely used by the Roman military. At an archaeological site, other plants were found that were used for medicinal purposes such as lentils, garden peas, and figs. A variety of meats were also discovered at

5076-599: The Netherlands and northern Germany. Birthwort (e.g. European birthwort A. clematitis ) refers to these species' flower shape, resembling a birth canal . Aristolochia was first described by the 4th c. BC Greek philosopher and botanist Theophrastus in his ‘’Inquiry of Plants’’ [IX.8.3], and the scientific name Aristolochia was developed from Ancient Greek aristos ( άριστος ) "best" + locheia ( λοχεία ), childbirth or childbed , relating to its known ancient use in childbirth. The Roman orator Cicero records

5184-626: The Roman army had a need for trained surgeons. The Romans conquered the city of Alexandria in 30 BC, which was an important center for learning ; its Great Library held countless volumes of ancient Greek medical information. The Romans adopted many of the practices and procedures they found in the Great Library. In 10 AD Augustus gave tax immunity to physicians practicing in Rome, as well as excluding them from public duties. These incentives caused uneducated and unqualified physicians to flood to Rome, causing tax exemption to only be offered to

5292-405: The Roman use of colostrum was more widespread and varied. Stories suggest that adults drinking breast milk was viewed as socially acceptable, but was not common unless used for treatment. The milk was instead ingested by the patient, and the treatment was given to both men and women, which then allowed the views of the female body to be viewed as analogous compared to their male peers, rather than as

5400-864: The Viridiplantae, along with the red algae and the glaucophytes , in the clade Archaeplastida . There are about 380,000 known species of plants, of which the majority, some 260,000, produce seeds . They range in size from single cells to the tallest trees . Green plants provide a substantial proportion of the world's molecular oxygen; the sugars they create supply the energy for most of Earth's ecosystems and other organisms , including animals, either eat plants directly or rely on organisms which do so. Grain , fruit , and vegetables are basic human foods and have been domesticated for millennia. People use plants for many purposes , such as building materials , ornaments, writing materials , and, in great variety, for medicines . The scientific study of plants

5508-801: The amount of cytoplasm stays the same. Most plants are multicellular . Plant cells differentiate into multiple cell types, forming tissues such as the vascular tissue with specialized xylem and phloem of leaf veins and stems , and organs with different physiological functions such as roots to absorb water and minerals, stems for support and to transport water and synthesized molecules, leaves for photosynthesis, and flowers for reproduction. Plants photosynthesize , manufacturing food molecules ( sugars ) using energy obtained from light . Plant cells contain chlorophylls inside their chloroplasts, which are green pigments that are used to capture light energy. The end-to-end chemical equation for photosynthesis is: This causes plants to release oxygen into

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5616-583: The army's expansion beyond the Italian Peninsula meant that the wounded could no longer be cared for in private homes. The temporary forts developed into permanent facilities over time. It is possible that some valteduinaria were established at earlier parts of history. They may also have been established by Julius Caesar . Other hospitals were possibly built during the reign of Augustus or Claudius . Valetudinaria were field hospitals or flying military camps primarily used to treat soldiers in

5724-449: The army, Dioscorides was able to experiment with the medical properties of many plants. Compared to his predecessors, his work was considered the largest and most thorough in regards to naming and writing about medicines, many of Dioscorides predecessors work was lost. Dioscorides wrote a 5-volume encyclopedia, De materia medica , which listed over 600 herbal cures, forming an influential and long-lasting pharmacopoeia . De materia medica

5832-431: The atmosphere. Green plants provide a substantial proportion of the world's molecular oxygen, alongside the contributions from photosynthetic algae and cyanobacteria. Plants that have secondarily adopted a parasitic lifestyle may lose the genes involved in photosynthesis and the production of chlorophyll. Growth is determined by the interaction of a plant's genome with its physical and biotic environment. Factors of

5940-417: The atoms were flowing freely and continuously, then the health of the human was maintained. He believed that if the atoms were too large or the pores were too constricted, then illness would present in multiple symptoms such as fever, spasms, or in more severe cases paralysis. Asclepiades strongly believed in hot and cold baths as a remedy for illness; his techniques purposely did not inflict severe pain upon

6048-467: The basis of the modern system of scientific classification , but retained the animal and plant kingdoms , naming the plant kingdom the Vegetabilia. When the name Plantae or plant is applied to a specific group of organisms or taxa , it usually refers to one of four concepts. From least to most inclusive, these four groupings are: There are about 382,000 accepted species of plants, of which

6156-503: The best they could hope for was that their treatments did not worsen their patients' problems. Many physicians were criticised by their peers for their inability to cure an apparently simple illness. Gaps in physician-provided care were filled with several types of supernatural healthcare; the Romans believed in the power of divine messages and healing. There have been descriptions of many gods from multiple religions that dealt with destruction or healing. For example, in 431 BC, in response to

6264-409: The body were affected by the movement or location of the sun, moon and planets. This is similar to horoscopic astrology and the notion of astrological signs. These celestial signs were only a part of the process in his work Critical Days . Galen also includes that the patients' feces, urine, sputum should be examined for diagnosis. He states that examination of the excrement could indicate a disease of

6372-519: The body. If the dreams were of normal everyday events, their body was healthy and in equilibrium. The farther from the norm, and the more chaotic the dreams were, the more ill the patient was. The treatments that were recommended addressed what the dreams showed, and attempted to set the body right through consumption of food that carried the correct humor characteristics. Galen wrote a treatise on diagnosis and prognosis by celestial movement. This ancient medical practice associated that disease and parts of

6480-530: The broader implications of the Greek influence on Roman society, the effect of ancient Greek medicine , ethnography, and meteorology was particularly pertinent to two fields: architecture and health care. This was particularly important from the perspective of the Roman army , in which there were many medical advances. A medical corpus was established, permanent physicians were appointed, the valetudinaria (military hospitals) were established, and in Caesar's time,

6588-595: The dead outside the city walls, their large supplies of water available through aqueducts, public bathing areas and public sewage systems. They also began draining swamps in close proximity to cities. One of the first prominent doctors in Rome was Galen . He became an expert on the human anatomy by dissecting animals, including monkeys, in Greece. Due to his prominence and expertise in ancient Rome, Galen became Emperor Marcus Aurelius ' personal physician. In 46 BC, Julius Caesar granted Roman citizenship to physicians when

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6696-488: The development of forests in swampy environments dominated by clubmosses and horsetails, including some as large as trees, and the appearance of early gymnosperms , the first seed plants . The Permo-Triassic extinction event radically changed the structures of communities. This may have set the scene for the evolution of flowering plants in the Triassic (~ 200  million years ago ), with an adaptive radiation in

6804-481: The elite, and were common throughout the Roman Empire. Reverence for shrines and statues reflected a search for healing, guidance, and alternatives to ineffectual human physicians and drugs. In 2013, Italian scientists studied the content of a Roman shipping vessel, known as the Relitto del Pozzino , sank off the coast of Populonia , Tuscany around 120 BC, which was excavated during the 1980s and 90s. The vessel had

6912-430: The first traces of systematic care for the wounded appeared. The variety and nature of the surgical instruments discovered in Roman remains indicate a good knowledge of surgery . Roman medicine was highly influenced by the Greek medical tradition. Prior to the introduction of Greek medicine Roman medicine was a combination of religion and magic. The first Roman physicians were religious figures with no medical training or

7020-399: The freedom to seek physicians, indicates that patient autonomy was valued. Roman physicians used a wide range of herbal and other medicines. Their ancient names, often derived from Greek, do not necessarily correspond to individual modern species, even if these have the same names. Known medicines include: Statues and healing shrines were sites of prayer and sacrifice for both the poor and

7128-409: The gametophyte is very small. Flowering plants reproduce sexually using flowers, which contain male and female parts: these may be within the same ( hermaphrodite ) flower, on different flowers on the same plant , or on different plants . The stamens create pollen , which produces male gametes that enter the ovule to fertilize the egg cell of the female gametophyte. Fertilization takes place within

7236-420: The god actually inhabited the sanctuary and would provide divine healing to supplicants. The process itself was simple: the sick person would give a specified donation to the temple, and then undergo a process called "incubation" in which they would relocate to a special room where the god would be able to contact them, often through dreams in which the god would either prescribe care or provide it themselves. Often

7344-452: The gods through rituals was believed to alleviate such events. Miasma was perceived to be the root cause of many diseases, whether caused by famine, wars, or plague. The concept of contagion was formulated, resulting in practices of quarantine and improved sanitation. The Romans established systems of public hygiene indicating there was an understanding that this was of importance to public health. This can be seen in their practices of burying

7452-479: The great impact that philosophy had on them. The popular belief was that philosophy created interest in medicine as opposed to medicine creating an interest in philosophy. Pedanius Dioscorides (c. 40–90 AD), was a Greek botanist, pharmacologist and physician who practiced in Rome during the reign of Nero . Dioscorides studied botany and pharmacology in Tarsus. He became a well-known army surgeon. While traveling with

7560-583: The great majority, some 283,000, produce seeds . The table below shows some species count estimates of different green plant (Viridiplantae) divisions . About 85–90% of all plants are flowering plants. Several projects are currently attempting to collect records on all plant species in online databases, e.g. the World Flora Online . Plants range in scale from single-celled organisms such as desmids (from 10  micrometres   (μm) across) and picozoa (less than 3 μm across), to

7668-719: The hardy A. durior of eastern North America, which was one of John Bartram 's many introductions to British gardens; in 1761 Bartram sent seeds he had collected in the Ohio River Valley to Peter Collinson in London, and Collinson gave them to the nurseryman James Gordon at Mile End to raise. The vine was soon adopted for creating for arbors "a canopy impenetrable to the rays of the sun, or moderate rain," as Dr John Sims noted in The Botanical Magazine , 1801. Plant See text Plants are

7776-444: The head of household. Greek medicine was introduced into Italy with the establishment and development of military and political contacts between the two regions. It was not until the introduction of the healing god Asclepius in 291 BC and the arrival of the Greek doctor Archagathus in 219 BC that foreign medicine was publicly accepted in Rome, mainly due to future overall adaptation to the Roman practices. Setting aside some of

7884-616: The head of the family. The first professional physicians were Greek physicians. Asclepiades of Bithynia arrived in 124 BC. He was a popular physician known for his kindness to his patients often prescribing wine, rest and a swinging couch. The incorporation of Greek medicine into Roman society allowed Rome to transform into a monumental city by 100 BC. Like Greek physicians, Roman physicians relied on naturalistic observations rather than on spiritual rituals; but that does not imply an absence of spiritual belief. Tragic famines and plagues were often attributed to divine punishment; and appeasement of

7992-494: The human body, physicians used a variety of surgical procedures for dissection that were carried out using many different instruments including forceps , scalpels and catheters . The Roman Empire was a complex and vigorous combination of Greek and Roman cultural elements forged through centuries of contact. Later Latin authors, notably Cato and Pliny , believed in a specific traditional Roman type of healing based on herbs, chants, prayers and charms easily available to and by

8100-466: The injured. In Rome, death was caused by a combination of poor sanitation, famine, disease, epidemics, malnutrition, and warfare; this led to high Roman mortality rates. The development of health services was prolonged by the unsympathetic attitudes of the Romans towards the sick, superstition, and religious beliefs. Ancient Roman hospitals were established by the 1st century BC as military hospitals known as valetudinaria . The valetudinaria began as

8208-529: The land 1,200  million years ago , but it was not until the Ordovician , around 450  million years ago , that the first land plants appeared, with a level of organisation like that of bryophytes. However, fossils of organisms with a flattened thallus in Precambrian rocks suggest that multicellular freshwater eukaryotes existed over 1000 mya. Primitive land plants began to diversify in

8316-412: The large water-filled central vacuole , chloroplasts , and the strong flexible cell wall , which is outside the cell membrane . Chloroplasts are derived from what was once a symbiosis of a non-photosynthetic cell and photosynthetic cyanobacteria . The cell wall, made mostly of cellulose , allows plant cells to swell up with water without bursting. The vacuole allows the cell to change in size while

8424-515: The largest trees ( megaflora ) such as the conifer Sequoia sempervirens (up to 120 metres (380 ft) tall) and the angiosperm Eucalyptus regnans (up to 100 m (325 ft) tall). The naming of plants is governed by the International Code of Nomenclature for algae, fungi, and plants and the International Code of Nomenclature for Cultivated Plants . The ancestors of land plants evolved in water. An algal scum formed on

8532-665: The late Silurian , around 420  million years ago . Bryophytes, club mosses, and ferns then appear in the fossil record. Early plant anatomy is preserved in cellular detail in an early Devonian fossil assemblage from the Rhynie chert . These early plants were preserved by being petrified in chert formed in silica-rich volcanic hot springs. By the end of the Devonian, most of the basic features of plants today were present, including roots, leaves and secondary wood in trees such as Archaeopteris . The Carboniferous period saw

8640-405: The leaf axils . They are inflated and globose at the base, continuing as a long perianth tube, ending in a tongue-shaped, brightly colored lobe. There is no corolla . The calyx is one to three whorled, and three to six toothed. The sepals are united (gamosepalous). There are six to 40 stamens in one whorl. They are united with the style, forming a gynostemium . The ovary is inferior and

8748-561: The margins of the abdomen because both the inner membrane and the surface skin needed to be sutured with two sets of stitches because it could be broken easily. The Romans applied a variety of ointments and dressings to these wounds. Celsus describes 34 different ones. Colostrum is the first form of milk produced by lactating mammals. Both Greek and Roman medical texts prescribe the use of a variety of substances, of varying medical and religious significance. Several substances, such as sulfur , asphalt and animal excrement, were associated with

8856-622: The mid-twentieth century, the Bencao Gangmu was replaced by modern Materia Medica , the most comprehensive source being Zhong Hua Ben Cao ( Encyclopedia of Chinese Materia Medica ), published in 1999. The Encyclopedia lists 23 species of Aristolochia , though with little mention of toxicity. The Chinese government currently lists the following Aristolochia herbs: A. manshuriensis (stems), A. fangchi (root), A. debilis (root and fruit), and A. contorta (fruit), two of which ( madouling and qingmuxiang ) appear in

8964-478: The milk used for medicinal purposes should be strictly from a woman who has borne a male child. The treatments using breast milk differed vastly between Greek and Roman culture. In Greek medicine, milk was very rarely actually consumed. Instead, it was used in recipes for ointments and washes that would treat burns and other skin-related maladies. These treatments were exclusively given to women, as women's bodies were viewed as "polluted" in some sense. In stark contrast,

9072-547: The most diverse climates. Some species, like A. utriformis and A. westlandii , are threatened with extinction . Isotrema is usually included here, but might be a valid genus. If so, it contains those species with a three-lobed calyx . Aristolochia is a genus of evergreen and deciduous lianas (woody vines) and herbaceous perennials . The smooth stem is erect or somewhat twining. The simple leaves are alternate and cordate , membranous, growing on leaf stalks. There are no stipules . The flowers grow in

9180-427: The opposites they have been for centuries before. In general, while not every single fear about the changing medical views of female physiology went away, the Romans then seemed less concerned about the so-called "pollution" of a woman's body and therefore need to have the women have special requirements needed for "purification." It has been shown in modern times that having patients ingest mother's milk (or colostrum)

9288-500: The patient and what must be done to set them back to equilibrium. The fourth book of the Regimen is the earliest mention of the topic of dream medicine. Dreams were used by physicians in diagnosis. They added another layer of depth to the physician's investigation of the patient. The soul was thought to serve the purpose that the brain has been discovered to serve. Sensation, pain, motion and other physiological concepts were thought to be

9396-507: The patient. Asclepiades used techniques with the intent to cause the least amount of discomfort while continuing to cure the patient. His other remedies included music therapy to induce sedation, and consuming wine to cure headache and a fever. Asclepiades is the first documented physician in Rome to use massage therapy. Celsus (25 BC–AD 50) was a Roman encyclopaedist who wrote a general encyclopaedia about many subjects. His exact place of birth as well as when he lived are unknown; however, it

9504-501: The physical or abiotic environment include temperature , water , light, carbon dioxide , and nutrients in the soil. Biotic factors that affect plant growth include crowding, grazing, beneficial symbiotic bacteria and fungi, and attacks by insects or plant diseases . Frost and dehydration can damage or kill plants. Some plants have antifreeze proteins , heat-shock proteins and sugars in their cytoplasm that enable them to tolerate these stresses . Plants are continuously exposed to

9612-468: The plague running rampant all over the country of Italy, the temple of the Apollo Medicus was accredited with an influence of healing. Scattered across Greco-Roman and Egyptian history are descriptions of healing sanctuaries dedicated to the various healing gods. Sick or injured Romans would often flock to Asclepieia , temples dedicated to Asclepius , the god of healing, as it was believed that

9720-538: The plant kingdom encompassed all living things that were not animals , and included algae and fungi . Definitions have narrowed since then; current definitions exclude the fungi and some of the algae. By the definition used in this article, plants form the clade Viridiplantae (green plants), which consists of the green algae and the embryophytes or land plants ( hornworts , liverworts , mosses , lycophytes , ferns , conifers and other gymnosperms , and flowering plants ). A definition based on genomes includes

9828-481: The practice of human purification. The practice of using a woman's breast milk as a medicine has very early roots in Egyptian medical texts. In several such texts there are references to the use of the milk of a woman who has given birth to a male child. This practice is said to be based on depictions in several statues of the goddess Isis breastfeeding her son, the god Horus . Both Egyptian and Greek texts state that

9936-421: The principles outlined by Galen : specifically the humors and examples of how they could be used to prescribe treatment. The theme of this method is knowing the patient. To know how to treat a person, the physician must become familiar with and interpret the important aspects of their lives: the climate, their food intake, how much they sleep, how much they drink, any injuries. They would then draw conclusions about

10044-546: The respirator system, urinary tract or vascular system. Many physicians at the time believed in the association of astrology and medicine. Book III of Galen's writing he correlates the lunar phases which cause changes in the tides to also cause changes the fluid humors in the body. He also makes reference to "medical months", which are based on the two periods of the moons which are about two calendar months. There were also days that were considered critical including day seven, fourteen and day twenty which were considered favorable for

10152-495: The same order. Aristolochic acid was linked to aristolochic acid-associated urothelial cancer in a Taiwanese study in 2012. In 2013, two studies reported that aristolochic acid is a strong carcinogen. Whole-genome and exome analysis of individuals with a known exposure to aristolochic acid revealed a higher rate of somatic mutation in DNA. Metabolites of aristolochic acid enter the cell nucleus and form adducts on DNA . While adducts on

10260-413: The site which were believed to be used for sick individuals. Poultry, eggs, and oysters were used as a diet for those with health issues. Moderation of foods was key to healthy living and gave rise to healthy eating philosophies. When diet no longer promoted health, drugs, phlebotomy , cautery , or surgery were used. Patients having control of their lives, managing their own preventative medical diets, and

10368-441: The sixteenth century, was based on the author's experience and on data obtained from earlier herbals; this Chinese herbal classic describes 1892 "drugs" (with 1110 drawings), including many species of Aristolochia . For 400 years, the Bencao Gangmu remained the principal source of information in traditional Chinese medicine and the work was translated into numerous languages, reflecting its influence in countries other than China. In

10476-469: The smallest published genome is that of the carnivorous bladderwort ( Utricularia gibba) at 82 Mb (although it still encodes 28,500 genes) while the largest, from the Norway spruce ( Picea abies ), extends over 19.6 Gb (encoding about 28,300 genes). Plants are distributed almost worldwide. While they inhabit several biomes which can be divided into a multitude of ecoregions , only the hardy plants of

10584-456: The theory behind how a treatment works. Celsus is also credited with writing on four of the five characteristics of inflammation, redness (rubor), swelling (tumour), heat (calor), and pain (dolor). Galen would write about the fifth, loss of function ( functio laesa ). Soranus was a Greek physician born in Ephesus, who lived during the reigns of Trajan and Hadrian (98–138 AD). According to

10692-463: The transcribed DNA strand within genes are detected and removed by transcription-coupled repair , the adducts on the non-transcribed strand remain and eventually cause DNA replication errors. These adducts have a preference for adenine bases, and cause A-to-T transversions . Furthermore, these metabolites appear to show a preference for C A G and T A G sequences. Due to their spectacular flowers, several species are used as ornamental plants , notably

10800-404: The type of cure prescribed would be rather similar to the actual medical practices of physicians of the time. This type of supernatural care did not conflict with mainstream healthcare. Physicians would often recommend that patients go to a healing sanctuary when they were afflicted by an illness that the physician could not cure. This allowed the reputation of the physician to remain unharmed, as it

10908-409: The uterus, the doctrine of signatures held that birthwort was useful in childbirth. A preparation was given to women upon delivery to expel the placenta , as noted by the herbalist Dioscurides in the 1st century AD. Despite its presence in ancient medicine, Aristolochia is known to contain the lethal toxin aristolochic acid . The Bencao Gangmu , compiled by Li Shi-Zhen in the latter part of

11016-411: The work of the soul. It was also thought that the soul continues the work of bodily upkeep even when a person is sleeping. Thus, dreams would show what ailed a person. There were two types of dreams associated with medicine: prophetic and diagnostic. Prophetic dreams were divine in origin and foretold good or bad tidings for the future. Diagnostic dreams were a result of the soul telling what afflicted

11124-453: Was a Roman army physician, Soranus was a representative for the Methodic school of medicine, Galen performed public demonstrations, and Asclepiades was a leading Roman physician. These four physicians all had knowledge of medicine, ailments, and treatments that were healing, long lasting and influential to human history. Ancient Roman medicine was divided into specializations such as ophthalmology and urology . To increase their knowledge of

11232-410: Was a rectangular building consisting of four wings, connected by an entrance hall that could be used as a triage center. Each legion's hospital was constructed to accommodate 6–10% of the legion's 5,000 men. The building also included a large hall, reception ward, dispensary, kitchen, staff quarters, and washing and latrine facilities. All of these hospitals were the exact same shape and layout, and one

11340-660: Was highly influenced by ancient Greek medicine , but also developed new practices through knowledge of the Hippocratic Corpus combined with use of the treatment of diet, regimen, along with surgical procedures . This was most notably seen through the works of two of the prominent Greek physicians, Dioscorides and Galen , who practiced medicine and recorded their discoveries. This is contrary to two other physicians like Soranus of Ephesus and Asclepiades of Bithynia , who practiced medicine both in outside territories and in ancient Roman territory, subsequently. Dioscorides

11448-414: Was located in every castra . Doctors could also set up public clinics in tabernae . Tabernae were another way of getting medical attention in ancient Rome. These facilities were very expensive, and there was no inpatient care . This method was rare; it was far more common for the physician to arrive at the patient's house. People who could not afford a doctor or go to a valetudinaria would pray at

11556-403: Was seen more as a referral than as a failure. Roman physicians tried their best to help treat battlefield wounds. Celsus describes treatments early Roman doctors used for battlefield abdominal wounds. Celsus describes that doctors should first observe the color of the intestines to see that if they are "...livid or pallid or black..." in which case treatment is impossible. If the large intestine

11664-429: Was used extensively by doctors for the following 1500 years. Within his five books, Dioscorides mentions approximately 1,000 simple drugs. Also ... contained in his books, Dioscorides refers to opium and mandragora as a sleeping potion that can be used as a natural surgical anesthetic. Galen of Pergamon (129 – c. AD 216) was a prominent Greek physician, whose theories dominated Western medical science for well over

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