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64-499: Basic research , also called pure research , fundamental research , basic science , or pure science , is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques, which can be used to intervene and alter natural or other phenomena. Though often driven simply by curiosity , basic research often fuels

128-447: A crucial experiment . If the experimental results confirm the predictions, then the hypotheses are considered more likely to be correct, but might still be wrong and continue to be subject to further testing. The experimental control is a technique for dealing with observational error. This technique uses the contrast between multiple samples, or observations, or populations, under differing conditions, to see what varies or what remains

192-410: A 1919 solar eclipse supported General Relativity rather than Newtonian gravitation . [REDACTED] Watson and Crick showed an initial (and incorrect) proposal for the structure of DNA to a team from King's College London – Rosalind Franklin , Maurice Wilkins , and Raymond Gosling . Franklin immediately spotted the flaws which concerned the water content. Later Watson saw Franklin's photo 51 ,

256-518: A controlled setting, such as a laboratory, or made on more or less inaccessible or unmanipulatable objects such as stars or human populations. The measurements often require specialized scientific instruments such as thermometers , spectroscopes , particle accelerators , or voltmeters , and the progress of a scientific field is usually intimately tied to their invention and improvement. I am not accustomed to saying anything with certainty after only one or two observations. The scientific definition of

320-411: A detailed X-ray diffraction image, which showed an X-shape and was able to confirm the structure was helical. Once predictions are made, they can be sought by experiments. If the test results contradict the predictions, the hypotheses which entailed them are called into question and become less tenable. Sometimes the experiments are conducted incorrectly or are not very well designed when compared to

384-433: A drug to cure this particular disease?" This stage frequently involves finding and evaluating evidence from previous experiments, personal scientific observations or assertions, as well as the work of other scientists. If the answer is already known, a different question that builds on the evidence can be posed. When applying the scientific method to research, determining a good question can be very difficult and it will affect

448-431: A guideline for proceeding: The iterative cycle inherent in this step-by-step method goes from point 3 to 6 and back to 3 again. While this schema outlines a typical hypothesis/testing method, many philosophers, historians, and sociologists of science, including Paul Feyerabend , claim that such descriptions of scientific method have little relation to the ways that science is actually practiced. The basic elements of

512-403: A phenomenon under study. Albert Einstein once observed that "there is no logical bridge between phenomena and their theoretical principles." Charles Sanders Peirce , borrowing a page from Aristotle ( Prior Analytics , 2.25 ) described the incipient stages of inquiry , instigated by the "irritation of doubt" to venture a plausible guess, as abductive reasoning . The history of science

576-434: A plane from New York to Paris is an experiment that tests the aerodynamical hypotheses used for constructing the plane. These institutions thereby reduce the research function to a cost/benefit, which is expressed as money, and the time and attention of the researchers to be expended, in exchange for a report to their constituents. Current large instruments, such as CERN's Large Hadron Collider (LHC), or LIGO , or

640-410: A predecessor idea, but perhaps more in its ability to stimulate the research that will illuminate ... bald suppositions and areas of vagueness. In general, scientists tend to look for theories that are " elegant " or " beautiful ". Scientists often use these terms to refer to a theory that is following the known facts but is nevertheless relatively simple and easy to handle. Occam's Razor serves as

704-561: A problem in the future. In the United States, basic research is funded mainly by the federal government and done mainly at universities and institutes. As government funding has diminished in the 2010s, however, private funding is increasingly important. Applied science focuses on the development of technology and techniques. In contrast, basic science develops scientific knowledge and predictions, principally in natural sciences but also in other empirical sciences, which are used as

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768-519: A rule of thumb for choosing the most desirable amongst a group of equally explanatory hypotheses. To minimize the confirmation bias that results from entertaining a single hypothesis, strong inference emphasizes the need for entertaining multiple alternative hypotheses, and avoiding artifacts. [REDACTED] James D. Watson , Francis Crick , and others hypothesized that DNA had a helical structure. This implied that DNA's X-ray diffraction pattern would be 'x shaped'. This prediction followed from

832-619: A set of phenomena. Normally, hypotheses have the form of a mathematical model . Sometimes, but not always, they can also be formulated as existential statements , stating that some particular instance of the phenomenon being studied has some characteristic and causal explanations, which have the general form of universal statements , stating that every instance of the phenomenon has a particular characteristic. Scientists are free to use whatever resources they have – their own creativity, ideas from other fields, inductive reasoning , Bayesian inference , and so on – to imagine possible explanations for

896-584: A term sometimes differs substantially from its natural language usage. For example, mass and weight overlap in meaning in common discourse, but have distinct meanings in mechanics . Scientific quantities are often characterized by their units of measure which can later be described in terms of conventional physical units when communicating the work. New theories are sometimes developed after realizing certain terms have not previously been sufficiently clearly defined. For example, Albert Einstein 's first paper on relativity begins by defining simultaneity and

960-578: Is a social enterprise, and scientific work tends to be accepted by the scientific community when it has been confirmed. Crucially, experimental and theoretical results must be reproduced by others within the scientific community. Researchers have given their lives for this vision; Georg Wilhelm Richmann was killed by ball lightning (1753) when attempting to replicate the 1752 kite-flying experiment of Benjamin Franklin . Science, technology, and society Too Many Requests If you report this error to

1024-399: Is essential that the outcome of testing such a prediction be currently unknown. Only in this case does a successful outcome increase the probability that the hypothesis is true. If the outcome is already known, it is called a consequence and should have already been considered while formulating the hypothesis . If the predictions are not accessible by observation or experience, the hypothesis

1088-424: Is filled with stories of scientists claiming a "flash of inspiration", or a hunch, which then motivated them to look for evidence to support or refute their idea. Michael Polanyi made such creativity the centerpiece of his discussion of methodology. William Glen observes that the success of a hypothesis, or its service to science, lies not simply in its perceived "truth", or power to displace, subsume or reduce

1152-417: Is not yet testable and so will remain to that extent unscientific in a strict sense. A new technology or theory might make the necessary experiments feasible. For example, while a hypothesis on the existence of other intelligent species may be convincing with scientifically based speculation, no known experiment can test this hypothesis. Therefore, science itself can have little to say about the possibility. In

1216-432: Is possible to identify a possible outcome of an experiment or observation that conflicts with predictions deduced from the hypothesis; otherwise, the hypothesis cannot be meaningfully tested. While the scientific method is often presented as a fixed sequence of steps, it actually represents a set of general principles. Not all steps take place in every scientific inquiry (nor to the same degree), and they are not always in

1280-461: Is the process by which science is carried out. As in other areas of inquiry, science (through the scientific method) can build on previous knowledge, and unify understanding of its studied topics over time. This model can be seen to underlie the scientific revolution . The overall process involves making conjectures ( hypotheses ), predicting their logical consequences, then carrying out experiments based on those predictions to determine whether

1344-717: The National Ignition Facility (NIF), or the International Space Station (ISS), or the James Webb Space Telescope (JWST), entail expected costs of billions of dollars, and timeframes extending over decades. These kinds of institutions affect public policy, on a national or even international basis, and the researchers would require shared access to such machines and their adjunct infrastructure . Scientists assume an attitude of openness and accountability on

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1408-474: The scientific revolution of the 16th and 17th centuries some of the most important developments were the furthering of empiricism by Francis Bacon and Robert Hooke , the rationalist approach described by René Descartes and inductivism , brought to particular prominence by Isaac Newton and those who followed him. Experiments were advocated by Francis Bacon , and performed by Giambattista della Porta , Johannes Kepler , and Galileo Galilei . There

1472-400: The technological innovations of applied science . The two aims are often practiced simultaneously in coordinated research and development . In addition to innovations, basic research serves to provide insights and public support of nature, possibly improving conservation efforts. Technological innovations may influence engineering concepts, such as the beak of a kingfisher influencing

1536-415: The visual system , rather than to study free will , for example. His cautionary example was the gene; the gene was much more poorly understood before Watson and Crick's pioneering discovery of the structure of DNA; it would have been counterproductive to spend much time on the definition of the gene, before them. [REDACTED] Linus Pauling proposed that DNA might be a triple helix . This hypothesis

1600-589: The "scientific method" and in doing so largely replaced the notion of science as a homogeneous and universal method with that of it being a heterogeneous and local practice. In particular, Paul Feyerabend, in the 1975 first edition of his book Against Method , argued against there being any universal rules of science ; Karl Popper , and Gauch 2003, disagree with Feyerabend's claim. Later stances include physicist Lee Smolin 's 2013 essay "There Is No Scientific Method", in which he espouses two ethical principles , and historian of science Daniel Thurs' chapter in

1664-453: The 17th century. The scientific method involves careful observation coupled with rigorous scepticism , because cognitive assumptions can distort the interpretation of the observation . Scientific inquiry includes creating a testable hypothesis through inductive reasoning , testing it through experiments and statistical analysis, and adjusting or discarding the hypothesis based on the results. Although procedures vary between fields ,

1728-449: The 1830s and 1850s, when Baconianism was popular, naturalists like William Whewell, John Herschel and John Stuart Mill engaged in debates over "induction" and "facts" and were focused on how to generate knowledge. In the late 19th and early 20th centuries, a debate over realism vs. antirealism was conducted as powerful scientific theories extended beyond the realm of the observable. The term "scientific method" came into popular use in

1792-425: The 2015 book Newton's Apple and Other Myths about Science , which concluded that the scientific method is a myth or, at best, an idealization. As myths are beliefs, they are subject to the narrative fallacy as Taleb points out. Philosophers Robert Nola and Howard Sankey, in their 2007 book Theories of Scientific Method , said that debates over the scientific method continue, and argued that Feyerabend, despite

1856-546: The Earth, while controlled experiments can be seen in the works of al-Battani (853–929 CE) and Alhazen (965–1039 CE). [REDACTED] Watson and Crick then produced their model, using this information along with the previously known information about DNA's composition, especially Chargaff's rules of base pairing. After considerable fruitless experimentation, being discouraged by their superior from continuing, and numerous false starts, Watson and Crick were able to infer

1920-527: The National Science Foundation. A worker in basic scientific research is motivated by a driving curiosity about the unknown. When his explorations yield new knowledge, he experiences the satisfaction of those who first attain the summit of a mountain or the upper reaches of a river flowing through unmapped territory. Discovery of truth and understanding of nature are his objectives. His professional standing among his fellows depends upon

1984-446: The basic method used for scientific inquiry. The scientific community and philosophers of science generally agree on the following classification of method components. These methodological elements and organization of procedures tend to be more characteristic of experimental sciences than social sciences . Nonetheless, the cycle of formulating hypotheses, testing and analyzing the results, and formulating new hypotheses, will resemble

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2048-461: The basis of progress and development in different fields. Today's computers, for example, could not exist without research in pure mathematics conducted over a century ago, for which there was no known practical application at the time. Basic research rarely helps practitioners directly with their everyday concerns; nevertheless, it stimulates new ways of thinking that have the potential to revolutionize and dramatically improve how practitioners deal with

2112-467: The contrary, if the astronomically massive, the feather-light, and the extremely fast are removed from Einstein's theories – all phenomena Newton could not have observed – Newton's equations are what remain. Einstein's theories are expansions and refinements of Newton's theories and, thus, increase confidence in Newton's work. An iterative, pragmatic scheme of the four points above is sometimes offered as

2176-553: The cycle described below. The scientific method is an iterative, cyclical process through which information is continually revised. It is generally recognized to develop advances in knowledge through the following elements, in varying combinations or contributions: Each element of the scientific method is subject to peer review for possible mistakes. These activities do not describe all that scientists do but apply mostly to experimental sciences (e.g., physics, chemistry, biology, and psychology). The elements above are often taught in

2240-525: The design of a high-speed bullet train. Basic research advances fundamental knowledge about the world. It focuses on creating and refuting or supporting theories that explain observed phenomena. Pure research is the source of most new scientific ideas and ways of thinking about the world. It can be exploratory , descriptive , or explanatory; however, explanatory research is the most common. Basic research generates new ideas, principles, and theories, which may not be immediately utilized but nonetheless form

2304-557: The educational system as "the scientific method". The scientific method is not a single recipe: it requires intelligence, imagination, and creativity. In this sense, it is not a mindless set of standards and procedures to follow but is rather an ongoing cycle , constantly developing more useful, accurate, and comprehensive models and methods. For example, when Einstein developed the Special and General Theories of Relativity, he did not in any way refute or discount Newton's Principia . On

2368-402: The essential structure of DNA by concrete modeling of the physical shapes of the nucleotides which comprise it. They were guided by the bond lengths which had been deduced by Linus Pauling and by Rosalind Franklin 's X-ray diffraction images. The scientific method is iterative. At any stage, it is possible to refine its accuracy and precision , so that some consideration will lead

2432-448: The experimental method, the hypothesis, or the definition of the subject. This manner of iteration can span decades and sometimes centuries. Published papers can be built upon. For example: By 1027, Alhazen , based on his measurements of the refraction of light, was able to deduce that outer space was less dense than air , that is: "the body of the heavens is rarer than the body of air". In 1079 Ibn Mu'adh 's Treatise On Twilight

2496-468: The future, a new technique may allow for an experimental test and the speculation would then become part of accepted science. For example, Einstein's theory of general relativity makes several specific predictions about the observable structure of spacetime , such as that light bends in a gravitational field , and that the amount of bending depends in a precise way on the strength of that gravitational field. Arthur Eddington 's observations made during

2560-405: The history of science, and eminent natural philosophers and scientists have argued for the primacy of various approaches to establishing scientific knowledge. Different early expressions of empiricism and the scientific method can be found throughout history, for instance with the ancient Stoics , Epicurus , Alhazen , Avicenna , Al-Biruni , Roger Bacon , and William of Ockham . In

2624-526: The means for determining length . These ideas were skipped over by Isaac Newton with, "I do not define time , space, place and motion , as being well known to all." Einstein's paper then demonstrates that they (viz., absolute time and length independent of motion) were approximations. Francis Crick cautions us that when characterizing a subject, however, it can be premature to define something when it remains ill-understood. In Crick's study of consciousness , he actually found it easier to study awareness in

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2688-535: The mechanism of storing genetic information (i.e., genes) in DNA was unclear. Researchers in Bragg's laboratory at Cambridge University made X-ray diffraction pictures of various molecules , starting with crystals of salt , and proceeding to more complicated substances. Using clues painstakingly assembled over decades, beginning with its chemical composition, it was determined that it should be possible to characterize

2752-405: The original conjecture was correct. However, there are difficulties in a formulaic statement of method. Though the scientific method is often presented as a fixed sequence of steps, these actions are more accurately general principles. Not all steps take place in every scientific inquiry (nor to the same degree), and they are not always done in the same order. There are different ways of outlining

2816-466: The originality and soundness of his work. Creativeness in science is of a cloth with that of the poet or painter. It conducted a study in which it traced the relationship between basic scientific research efforts and the development of major innovations, such as oral contraceptives and videotape recorders. This study found that basic research played a key role in the development in all of the innovations. The number of basic science research that assisted in

2880-431: The outcome of the investigation. The systematic, careful collection of measurements or counts of relevant quantities is often the critical difference between pseudo-sciences , such as alchemy, and science, such as chemistry or biology. Scientific measurements are usually tabulated, graphed, or mapped, and statistical manipulations, such as correlation and regression , performed on them. The measurements might be made in

2944-403: The part of those experimenting. Detailed record-keeping is essential, to aid in recording and reporting on the experimental results, and supports the effectiveness and integrity of the procedure. They will also assist in reproducing the experimental results, likely by others. Traces of this approach can be seen in the work of Hipparchus (190–120 BCE), when determining a value for the precession of

3008-403: The pertinent properties of the subjects, careful thought may also entail some definitions and observations ; these observations often demand careful measurements and/or counting can take the form of expansive empirical research . A scientific question can refer to the explanation of a specific observation , as in "Why is the sky blue?" but can also be open-ended, as in "How can I design

3072-532: The physical structure of DNA, and the X-ray images would be the vehicle. The scientific method depends upon increasingly sophisticated characterizations of the subjects of investigation. (The subjects can also be called unsolved problems or the unknowns .) For example, Benjamin Franklin conjectured, correctly, that St. Elmo's fire was electrical in nature , but it has taken a long series of experiments and theoretical changes to establish this. While seeking

3136-424: The process at any stage. They might adopt the characterization and formulate their own hypothesis, or they might adopt the hypothesis and deduce their own predictions. Often the experiment is not done by the person who made the prediction, and the characterization is based on experiments done by someone else. Published results of experiments can also serve as a hypothesis predicting their own reproducibility. Science

3200-755: The production of a given innovation peaked between 20 and 30 years before the innovation itself. While most innovation takes the form of applied science and most innovation occurs in the private sector, basic research is a necessary precursor to almost all applied science and associated instances of innovation. Roughly 76% of basic research is conducted by universities. A distinction can be made between basic science and disciplines such as medicine and technology. They can be grouped as STM (science, technology, and medicine; not to be confused with STEM [science, technology, engineering, and mathematics]) or STS (science, technology, and society). These groups are interrelated and influence each other, although they may differ in

3264-443: The same order. Numerous discoveries have not followed the textbook model of the scientific method and chance has played a role, for instance. The history of scientific method considers changes in the methodology of scientific inquiry, not the history of science itself. The development of rules for scientific reasoning has not been straightforward; scientific method has been the subject of intense and recurring debate throughout

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3328-461: The same. We vary the conditions for the acts of measurement, to help isolate what has changed. Mill's canons can then help us figure out what the important factor is. Factor analysis is one technique for discovering the important factor in an effect. Depending on the predictions, the experiments can have different shapes. It could be a classical experiment in a laboratory setting, a double-blind study or an archaeological excavation . Even taking

3392-453: The scientific foundation for applied science. Basic science develops and establishes information to predict phenomena and perhaps to understand nature, whereas applied science uses portions of basic science to develop interventions via technology or technique to alter events or outcomes. Applied and basic sciences can interface closely in research and development . The interface between basic research and applied research has been studied by

3456-422: The scientific method are illustrated by the following example (which occurred from 1944 to 1953) from the discovery of the structure of DNA (marked with [REDACTED] and indented). [REDACTED] In 1950, it was known that genetic inheritance had a mathematical description, starting with the studies of Gregor Mendel , and that DNA contained genetic information (Oswald Avery's transforming principle ). But

3520-413: The scientist to repeat an earlier part of the process. Failure to develop an interesting hypothesis may lead a scientist to re-define the subject under consideration. Failure of a hypothesis to produce interesting and testable predictions may lead to reconsideration of the hypothesis or of the definition of the subject. Failure of an experiment to produce interesting results may lead a scientist to reconsider

3584-411: The specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material". Any useful hypothesis will enable predictions , by reasoning including deductive reasoning . It might predict the outcome of an experiment in a laboratory setting or the observation of a phenomenon in nature. The prediction can also be statistical and deal only with probabilities. It

3648-535: The specifics such as methods and standards. The Nobel Prize mixes basic with applied sciences for its award in Physiology or Medicine . In contrast, the Royal Society of London awards distinguish natural science from applied science. Scientific research The scientific method is an empirical method for acquiring knowledge that has been referred to while doing science since at least

3712-582: The title of Against Method , accepted certain rules of method and attempted to justify those rules with a meta methodology. Staddon (2017) argues it is a mistake to try following rules in the absence of an algorithmic scientific method; in that case, "science is best understood through examples". But algorithmic methods, such as disproof of existing theory by experiment have been used since Alhacen (1027) and his Book of Optics , and Galileo (1638) and his Two New Sciences , and The Assayer , which still stand as scientific method. The scientific method

3776-416: The twentieth century; Dewey's 1910 book , How We Think , inspired popular guidelines , appearing in dictionaries and science textbooks, although there was little consensus over its meaning. Although there was growth through the middle of the twentieth century, by the 1960s and 1970s numerous influential philosophers of science such as Thomas Kuhn and Paul Feyerabend had questioned the universality of

3840-456: The underlying process is often similar. In more detail: the scientific method involves making conjectures (hypothetical explanations), predicting the logical consequences of hypothesis, then carrying out experiments or empirical observations based on those predictions. A hypothesis is a conjecture based on knowledge obtained while seeking answers to the question. Hypotheses can be very specific or broad but must be falsifiable , implying that it

3904-434: The work of Cochran, Crick and Vand (and independently by Stokes). The Cochran-Crick-Vand-Stokes theorem provided a mathematical explanation for the empirical observation that diffraction from helical structures produces x-shaped patterns. In their first paper, Watson and Crick also noted that the double helix structure they proposed provided a simple mechanism for DNA replication , writing, "It has not escaped our notice that

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3968-405: Was able to infer that Earth's atmosphere was 50 miles thick, based on atmospheric refraction of the sun's rays. This is why the scientific method is often represented as circular – new information leads to new characterisations, and the cycle of science continues. Measurements collected can be archived , passed onwards and used by others. Other scientists may start their own research and enter

4032-409: Was also considered by Francis Crick and James D. Watson but discarded. When Watson and Crick learned of Pauling's hypothesis, they understood from existing data that Pauling was wrong. and that Pauling would soon admit his difficulties with that structure. A hypothesis is a suggested explanation of a phenomenon, or alternately a reasoned proposal suggesting a possible correlation between or among

4096-587: Was particular development aided by theoretical works by a skeptic Francisco Sanches , by idealists as well as empiricists John Locke , George Berkeley , and David Hume . C. S. Peirce formulated the hypothetico-deductive model in the 20th century, and the model has undergone significant revision since. The term "scientific method" emerged in the 19th century, as a result of significant institutional development of science, and terminologies establishing clear boundaries between science and non-science, such as "scientist" and "pseudoscience", appearing. Throughout

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