74-541: The United States Army Reserve Legal Command ( USARLC ) is headquartered in Gaithersburg, Maryland , and was activated on 16 September 2009. It is part of United States Army Reserve Command . The U.S. Army Reserve Legal Command is headquartered at the Major General Benjamin L. Hunton Memorial United States Army Reserve Center at 8791 Snouffer School Road in Gaithersburg, Maryland . The mission of
148-545: A BRCA genetic mutation. A major criterion governing the drugs approval was, on average, its ability to shrink tumours in patients for 7.9 months. In February 2015, the company announced it would acquire the US and Canadian rights to Actavis's branded respiratory drug business for an initial sum of US$ 600 million. Later in the same month the company announced it would partner with Orca Pharmaceuticals to develop retinoic acid -related orphan nuclear receptor gamma inhibitors for use in
222-472: A bus rapid transit line, Corridor Cities Transitway or "CCT", planned for the western portion of the city starting at Shady Grove Metro Station and connecting all the high-density western Gaithersburg neighborhoods with a total of eight stops planned in the city. The National Institute of Standards and Technology (NIST) is headquartered in Gaithersburg directly west of I-270. Other major employers in
296-550: A clinical trial of tremelimumab as a treatment for mesothelioma failed to meet its primary endpoint. As of 2008, David Brennan was paid US$ 1,574,144 for his role as chief executive officer. On 26 April 2012, it was announced that Brennan was to retire in early June of that year. In August 2012, Pascal Soriot was named CEO of AstraZeneca. It was also announced that Leif Johansson would succeed Louis Schweitzer as non-executive chairman on 1 June 2012, three months earlier than previously announced, and would become Chairman of
370-470: A "final offer" from Pfizer of £55 per share, which valued the company at £69.4 billion (US$ 117 billion). The companies had been meeting since January 2014. If the takeover had proceeded, Pfizer would have become the world's biggest drug maker. The transaction would also have been the biggest foreign takeover of a British company. Many in Britain, including politicians and scientists, had opposed
444-474: A Phase I/II trial collaboration with Pharmacyclics and Janssen Biotech investigating combination treatments. Also in November of the same year, the company agreed to sell its lipodystrophy treatment business to Aegerion Pharmaceuticals for more than US$ 325 million. In December, the company received accelerated FDA approval for Olaparib in the treatment of women with advanced ovarian cancer who have
518-588: A city in 1968. Gaithersburg is located east and west of Interstate 270 . The eastern section includes the historic area of the town. Landmarks and buildings from that time can still be seen in many places but especially in the historic central business district of Gaithersburg called "Olde Towne". The east side also includes City Hall, the Montgomery County Fairgrounds, and Bohrer Park (a well-known joint community recreation center and outdoor water park for kids and families). The west side of
592-608: A cost of approximately £1 billion. In 2015 AstraZeneca arranged for the establishment of a direct air route between Cambridge and Gothenburg , which began operation on March 2, 2015. The company reserved 20 of the 32 seats on each flight, with the remaining seats available to the public, which was operated SUN-AIR for British Airways . The service connects AstraZeneca’s global headquarters in Cambridge with its research facility in Gothenburg. The service operated four days
666-690: A deal valued at up to $ 1.2 billion. Both the acquisitions were completed in February 2024. In March 2024, AstraZeneca announced it would acquire Amolyt Pharma for $ 1.05 billion in cash. In March 2024, AstraZeneca announced it would acquire Fusion Pharmaceuticals Inc for $ 2 billion in cash. In July 2024, National Institute for Health and Care Excellence (Nice) blocked the National Health Service (NHS) from providing Enhertu , an innovative treatment for advanced HER2-low breast cancer, due to AstraZeneca and Daiichi Sankyo not offering
740-623: A low enough price. Nice's decision, the first rejection of a breast cancer treatment in six years, highlighted the financial challenges of funding complex medicines, with Enhertu costing £117,857 per treatment course. Despite approval by the Medicines and Healthcare Regulatory Agency, Nice's non-recommendation meant the drug could only be available privately or under separate funding in Scotland. Clinical trials showed Enhertu extended patients' lives by five months compared to chemotherapy, but Nice and
814-808: A major corporate restructuring, including the closure of its research and development activities at Alderley Park in Cheshire and Loughborough in the UK and at Lund in Sweden, investment of $ 500 million in the construction of a new research and development facility in Cambridge and the concentration of R&D in three locations: Cambridge, Gaithersburg, Maryland (location of MedImmune, where it will work on biotech drugs), and Gothenburg in Sweden, for research on traditional chemical drugs. AstraZeneca also announced that it would move its corporate headquarters from London to Cambridge in 2016. That announcement included
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#1732781186194888-539: A new Cambridge– Gothenburg service by Sun-Air of Scandinavia . In mid-March the company announced it would co-commercialise naloxegol along with Daiichi Sankyo in a deal worth up to US$ 825 million. Towards the end of April the company announced a number of collaborations worth an estimated US$ 1.8 billion; first, to develop and commercialise MEDI4736, with Celgene , for use against non-Hodgkin’s lymphoma , myelodysplastic syndromes, and multiple myeloma with AstraZeneca receiving US$ 450 million. The second of two deals
962-467: A new global health tech business, Evinova, that focused on provide global services to CROs and pharma companies to design, run and monitor clinical trials. In December 2023, AstraZeneca announced that it would acquire an RSV vaccine developer, Icosavax for $ 1.1 billion. Later that month, AstraZeneca agreed to acquire clinical-stage biopharmaceutical developer of cell therapies for the treatment of cancer and autoimmune diseases, Gracell Biotechnologies, in
1036-616: A project to measure the Earth's wobble on its polar axis. The Gaithersburg Latitude Observatory is (as of 2007) the only National Historic Landmark in the City of Gaithersburg. The observatory and five others in Japan , Italy , Russia , and the United States gathered information that is still used by scientists today, along with information from satellites , to determine polar motion ;
1110-665: A spin-off of the Sanofi-Aventis anti-infectives division. Astra acquired the experimental antibiotic NXL-104 (CEF104) (CAZ-AVI) through this acquisition. In 2011, AstraZeneca acquired Guangdong BeiKang Pharmaceutical Company, a Chinese generics business. In February 2012, AstraZeneca and Amgen announced a collaboration on treatments for inflammatory diseases. Then in April 2012, AstraZeneca acquired Ardea Biosciences, another biotechnology company, for $ 1.26 billion. In June 2012, AstraZeneca and Bristol Myers Squibb announced
1184-440: A third station — Washington Grove — just outside city limits. Bus service in Gaithersburg consists of Metrobus routes operated by WMATA and Ride-On routes operated by Montgomery County , as well as paratransit service provided by MetroAccess . Montgomery County Airpark is located 3 miles (5 km) northeast of the city. AstraZeneca AstraZeneca plc ( / ˌ æ s t r ə ˈ z ɛ n ə k ə / ) ( AZ )
1258-493: A three-year collaboration with Mitsubishi Tanabe Pharma on diabetic nephropathy . In September 2014 the company would join forces with Eli Lilly in developing and commercialising its candidate BACE inhibitor – AZD3292 – used for the treatment of Alzheimer's disease . The deal could yield up to US$ 500 million for the company. In November 2014 the company's biologics R&D operation, MedImmune, agreed to acquire Definiens for more than US$ 150 million. The company also began
1332-543: A two-stage deal for the joint acquisition of the biotechnology company Amylin Pharmaceuticals . It was agreed that Bristol Myers Squibb would acquire Amylin for $ 5.3 billion in cash and the assumption of $ 1.7 billion in debt, with AstraZeneca then paying $ 3.4 billion in cash to Bristol Myers Squibb, and Amylin being folded into an existing diabetes joint venture between AstraZeneca and Bristol Myers Squibb. In March 2013 AstraZeneca announced plans for
1406-523: A week and was intended to support collaboration between staff in the two locations, allowing same-day travel for meetings. The route ended as a scheduled public service in 2016 due to insufficient demand, but these flights continue for AstraZeneca employees as of 2024. In April 2015, AstraZeneca's drug tremelimumab was approved as an orphan drug for the treatment of mesothelioma in the United States. In February 2016, AstraZeneca announced that
1480-543: Is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge , England. It has a portfolio of products for major diseases in areas including oncology , cardiovascular , gastrointestinal , infection , neuroscience , respiratory , and inflammation . The company was founded in 1999 through the merger of
1554-525: Is a city in Montgomery County, Maryland , United States. At the time of the 2020 census , Gaithersburg had a population of 69,657, making it the ninth-most populous community in the state. Gaithersburg is located to the northwest of Washington, D.C. , and is considered a suburb and a primary city within the Washington metropolitan area . Gaithersburg was incorporated as a town in 1878 and as
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#17327811861941628-446: Is an agreement to study a combination treatment of MEDI4736 and Innate Pharma's Phase II anti-NKG2A antibody IPH2201 for up to US$ 1.275 billion. The company's MedImmune arm also launched collaborative clinical trials with Juno Therapeutics , investigating combination treatments for cancer. The trials will assess combinations of MEDI4736 and one of Juno Therapeutics' CD19 directed chimeric antigen receptor T-cell candidates. In late June
1702-501: Is located just outside the city limits and is the north-western terminus of the Red Line . The Corridor Cities Transitway is a proposed bus rapid transit line that would have 8 stops in Gaithersburg, generally in the western half of the city. Maryland's MARC system operates commuter rail services connecting Gaithersburg to Washington, D.C. , with two stations in the city, at Old Town Gaithersburg and Metropolitan Grove , and
1776-725: Is on the London Stock Exchange and is a constituent of the FTSE 100 Index ; it also has a secondary listing on the Nasdaq Stockholm . It is also listed on the American Nasdaq and is a Nasdaq-100 company. AstraZeneca has one of the highest market capitalisations of pharmaceutical companies worldwide. Astra AB was founded in 1913 in Södertälje , Sweden , by 400 doctors and apothecaries . In 1993
1850-471: Is subordinate to the U.S. Army Reserve Command. The USARLC is composed predominantly of U.S. Army Reserve Soldiers. These personnel include judge advocates , warrant officers , paralegal noncommissioned officers , junior enlisted personnel, and civilian employees. The USARLC has 28 subordinate units located in 41 states and 104 cities including Puerto Rico . These units are called Legal Operations Detachments (LOD). Brigadier General Gerald R. Krimbill
1924-496: Is the commanding general. The command chief warrant officer is Chief Warrant Officer Four Hector X. Colon. The senior non-commissioned officer is Command Sergeant Major Carlos V. Arrieta Jr. USARLC was activated on 16 September 2009. The first commanding general for USARLC was Brigadier General Gill Beck, who served from 16 September 2009 until 29 September 2011. Gaithersburg, Maryland Gaithersburg ( / ˈ ɡ eɪ θ ər z b ɜːr ɡ / GAY -thərz-burg )
1998-537: Is the main highway leading northwest out of metropolitan Washington, D.C., beginning at Interstate 495 (the Capital Beltway) and proceeding northwestward to Interstate 70 in Frederick . I-370 is a short spur, starting just west of I-270 in Gaithersburg and heading east to its junction with Maryland Route 200 . Via MD 200, I-370 connects Gaithersburg with Interstate 95 near Laurel . Maryland Route 355
2072-491: The Cambridge Biomedical Campus adjacent to Addenbrooke's Hospital in Cambridge , United Kingdom . This facility, known as the Discovery Centre , was designed by Swiss architecture firm Herzog & de Meuron and officially opened by Prince Charles on the 23 November 2021. The building is designed to accommodate over 2,200 scientists across 16 laboratories covering approximately 19,000 square meters. built at
2146-635: The census of 2010, there were 59,933 people, 22,000 households, and 14,548 families residing in the city. The population density was 5,875.8 inhabitants per square mile (2,268.7/km ). There were 23,337 housing units at an average density of 2,287.9 per square mile (883.4/km ). The racial makeup of the city was 31.9% non-Hispanic White , 16.3% African American , 0.5% Native American , 16.9% Asian (6.01 Chinese, 4.77% Indian, 2.03% Korean, 1.69% Filipino, 1.02% Vietnamese, 0.62% Burmese), 0.1% Pacific Islander , 10.7% from other races , and 4.8% from two or more races. Hispanic or Latino of any race were 24.2% of
2220-529: The American pharmaceutical business, Moderna . In March 2019, AstraZeneca announced it will pay up to US$ 6.9 billion to work with Daiichi Sankyo Co Ltd on an experimental treatment for breast cancer. AstraZeneca plans to use some of the proceeds of a US$ 3.5 billion share issue to fund the deal. The deal on the drug known as trastuzumab deruxtecan sent shares in Japan's Daiichi soaring 16%. In September 2019,
2294-666: The British chemicals company ICI (established from four British chemical companies) demerged its pharmaceuticals businesses and its agrochemicals and specialities businesses, to form Zeneca Group PLC . Finally, in 1999 Astra and Zeneca Group merged to form AstraZeneca plc, with its headquarters in London. In 1999, AstraZeneca identified a new location for the company's US base, the "Fairfax-plus" site in North Wilmington , Delaware. In 2002, its drug Iressa (gefitinib)
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2368-466: The Pennsylvania Bio commerce organisation. In 2006, following a collaborative relationship begun in 2004, AstraZeneca acquired Cambridge Antibody Technology for £702 million. In February 2007, AstraZeneca agreed to buy Arrow Therapeutics, a company focused on the discovery and development of anti-viral therapies, for US$ 150 million. AstraZeneca's pipeline, and "patent cliff", was
2442-853: The Swedish Astra AB and the British Zeneca Group (itself formed by the demerger of the pharmaceutical operations of Imperial Chemical Industries in 1993). Since the merger it has been among the world's largest pharmaceutical companies and has made numerous corporate acquisitions, including Cambridge Antibody Technology (in 2006), MedImmune (in 2007), Spirogen (in 2013) and Definiens (by MedImmune in 2014). It has its research and development concentrated in three strategic centres: Cambridge, England; Gothenburg , Sweden and Gaithersburg in Maryland , U.S. AstraZeneca traces its earliest corporate history to 1913, when Astra AB
2516-440: The U.S. Army Reserve Legal Command (USARLC) is to ensure the availability of legal forces able to support national strategy in times of peace and war. It is composed of nearly 1,500 Soldiers and Civilians. USARLC is responsible for all of the operational tasks for the subordinate units that report to USARLC. These operational tasks include training, equipping, managing, supporting, mobilizing and retaining Soldiers under USARLC. USARLC
2590-615: The United Kingdom approved the emergency use of the Oxford–AstraZeneca COVID-19 vaccine . In July 2021, AstraZeneca acquired Alexion Pharmaceuticals . In October 2021, the company, through Alexion, acquired Caelum Biosciences and its monoclonal treatment (CAEL-101) for light chain (AL) amyloidosis for up to $ 500 million. In July, the company announced it would acquire TeneoTwo for up to $ 1.3 billion, increasing its blood cancer drug offering. In October 2022 it
2664-409: The United Kingdom. However, it had slowed decision making for new investment projects waiting for a post-Brexit regulatory regime to settle down. In September 2017, the company's chairman Leif Johansson planned in taking the "first steps" in moving its research and manufacturing operations away from the United Kingdom, if there is a hard Brexit. In 2017, it was the eleventh largest drug company in
2738-439: The announcement that it would cut 1,600 jobs; three days later it announced it would cut an additional 2,300 jobs. It also announced that it would focus on three therapeutic areas: Respiratory Inflammation & Autoimmunity, Cardiovascular & Metabolic Disease, and Oncology. In October 2013, AstraZeneca announced it would acquire biotech oncology company Spirogen for around US$ 440 million. On 19 May 2014 AstraZeneca rejected
2812-500: The area. Gaithersburg is also the location of the United States Army Reserve Legal Command . According to the U.S. Census Bureau , the city has a total area of 10.34 square miles (26.78 km ), of which 10.20 square miles (26.42 km ) is land and 0.14 square miles (0.36 km ) is water. As of the 2022 American Community Survey , there were 68,952 people and 24,523 households in
2886-408: The average family size was 3.14 the population was spread out, with 25.0% under the age of 18, 9.0% from 18 to 24, 37.7% from 25 to 44, 20.0% from 45 to 64, and 8.2% who were 65 years of age or older. The median age was 34 years. For every 100 females, there were 95.1 males. For every 100 females age 18 and over, there were 92.4 males. According to the city's 2020 Comprehensive Annual Financial Report,
2960-608: The city has many wealthier neighborhoods that were designed with smart growth techniques and embrace New Urbanism . These include the Kentlands community, the Lakelands community, and the Washingtonian Center (better known as Rio), a shopping/business district. Two New Urbanism communities are under construction, including Watkins Mill Town Center (Casey East and West), and the massive "Science City" . The state has
3034-545: The city include IBM , Lockheed Martin Information Systems and Global Services business area headquarters, AstraZeneca . Gaithersburg is also the location of the garrison of the United States Army Reserve Legal Command . Gaithersburg is noted for its ethnic and economic diversity; it was ranked second for ethnic diversity among the 501 largest U.S. cities, and first among smaller U.S. cities, by WalletHub in 2021. In 2023, Wallethub announced that Gaithersburg
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3108-484: The city of Gaithersburg and their directors include: The following Montgomery County Public Schools are located in Gaithersburg: Gaithersburg is primarily served by the Washington, D.C. media market . Being a city, Gaithersburg also has its own police department, which was created in 1963. The most prominent highways serving Gaithersburg are Interstate 270 and Interstate 370 . I-270
3182-542: The city. When the railroad was built through town in 1873, the new station was called Gaithersburg, an officially recognized name for the community for the first time. Also in 1873 the Baltimore and Ohio Railroad constructed a station at Gaithersburg, designed by Ephraim Francis Baldwin as part of his well-known series of Victorian stations in Maryland. Rapid growth occurred shortly thereafter, and on April 5, 1878,
3256-488: The city. The population density was 5,216.2 inhabitants per square mile (2,014.0/km ). There were 20,674 housing units at an average density of 2,049.7 per square mile (791.4/km ). The racial makeup of the city is 34.7% White , 19.5% Black or African American , 0.2% Native American , 13.9% Asian , 0.1% Pacific Islander , 3.6% from other races , and 3.2% from two or more races. 24.8% of the population were Hispanic or Latino of any race. 34.3% of Gaithersburg's population
3330-681: The companies could not agree on a new price. The following is an illustration of the company's major mergers and acquisitions and historical predecessors: AstraZeneca develops, manufactures and sells pharmaceutical and biotechnology products to treat disorders in the oncology , cardiovascular , gastrointestinal , infection , neuroscience , respiratory and inflammation areas. AstraZeneca has its corporate headquarters in Cambridge, United Kingdom, and its main research and development (R&D) centres are in Cambridge (UK), Gaithersburg (Maryland, US), Gothenburg (Sweden) and Warsaw (Poland). AstraZeneca's global headquarters are located in
3404-622: The company announced it had acquired the global rights to develop and commercialise Heptares Therapeutics' drug candidate HTL-1071, which focuses on blocking the adenosine A2A receptor, in a deal worth up to US$ 510 million. In the same month the company's MedImmune subsidiary acquired exclusive rights to Inovio Pharmaceuticals' INO-3112 immunotherapy, currently in Phase I/II, under an agreement which could net more than US$ 727.5 million for Inovio. INO-3112 targets Human papillomavirus types 16 and 18. In September, Valeant licensed Brodalumab from
3478-559: The company announced it has entered into a partnership agreement with Eolas Therapeutics on the Eolas Orexin-1 Receptor Antagonist (EORA) program for smoking cessation and other treatments. In July the company announced it would sell off its rights to Entocort ( budesonide ) to Tillotts Pharma for US$ 215 million. In July 2015, Genzyme announced it would acquire the rare cancer drug Caprelsa ( vandetanib ) from AstraZeneca for up to US$ 300 million. In August,
3552-526: The company announced that it would cease drug production at its German headquarters in Wedel , leading to the loss of 175 jobs by the end of 2021. In October 2019, AstraZeneca announced it would sell the global commercial rights for its drug to treat acid reflux to German pharmaceutical company Cheplapharm Arzneimittel GmbH for as much as US$ 276 million. In February 2020, AstraZeneca agreed to sublicense its global rights (except Europe, Canada and Israel) to
3626-458: The company for up to US$ 445 million. On 6 November it was reported that AstraZeneca had acquired ZS Pharma for US$ 2.7 billion. In December the company announced its intention to acquire the respiratory portfolio of Takeda Pharmaceutical – namely Alvesco and Omnaris – for US$ 575 million A day later, the company announced it had taken a 55% majority stake in Acerta for US$ 4 billion. As part of
3700-608: The council. The day-to-day administration of the city is overseen by a career city manager . The city's current mayor is Jud Ashman, who has held the office since 2014. On October 6, 2014, the Gaithersburg City Council selected city council member Jud Ashman to serve as mayor until the next City of Gaithersburg election in November 2015, replacing resigning mayor Sidney Katz . Ashman was re-elected in November 2015 and would be re-elected to full terms in 2017 and 2021. Previous mayors include: The departments of
3774-470: The deal. In July 2014 the company entered into a deal with Almirall to acquire its subsidiary Almirall Sofotec and its lung treatments including the COPD drug, Eklira. The US$ 2.1 billion deal included an allocation of US$ 1.2 billion for development in the respiratory franchise, one of AstraZeneca's three target therapeutic areas announced the year before. In August 2014 the company announced it had entered into
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#17327811861943848-517: The development of DS-1062, an antibody drug conjugate. The deal could potentially be worth up to US$ 6 billion for Daiichi. In September 2020, AstraZeneca acquired the preclinical oral PCSK9 inhibitor program from Dogma Therapeutics. On 27 December 2020, AstraZeneca CEO Pascal Soriot said that they have “figured out the winning formula” with their two-dose system with the Oxford University ’s COVID-19 vaccine . On 30 December 2020,
3922-437: The drug Movantik , to Redhill Biopharma. In June 2020, AstraZeneca made a preliminary approach to Gilead Sciences about a potential merger, worth almost US$ 240 billion. However, these plans were subsequently dropped because it would have distracted the company from its own pipeline and ongoing COVID-19 vaccine efforts. In July 2020, the business entered into its second collaboration with Daiichi Sankyo , centred around
3996-616: The film Body of Lies were filmed in the city, at a building on 100 Edison Park Drive. The film was released in 2008 and the building is now the Montgomery County Police Department 's headquarters. On July 16, 2010, Gaithersburg was part of the area where a 3.6 magnitude earthquake was felt, one of the strongest to occur in Maryland. After years of decline and loss of tenants, including three of its four anchor stores in 2019, Lakeforest Mall closed on March 31, 2023, with plans to demolish it and redevelop
4070-456: The landmark IBM Headquarters complex built on the then-new I-270 Interstate "Industrial", now "Technology", Corridor in the late 1960s to the 1970s. Benjamin Gaither married Henry's daughter Margaret, and Benjamin and Margaret inherited a portion of Henry's land prior to Henry's death in 1807. Gaither built his home on the land in 1802. By the 1850s the area had ceased to be called Log Town and
4144-474: The local schools, with Gaithersburg High School and Watkins Mill High School having two of the most diverse student bodies in the region. During a 1997 rainstorm, the 295-year-old forest oak tree that gave its name to the Forest Oak Post Office crashed down. The tree served as the inspiration for the city's logo, which is also featured prominently on the city's flag. In 2007, parts of
4218-462: The population (8.3% Salvadoran, 2% Honduran, 1.9% Mexican, 1.9% Peruvian, 1.7% Guatemalan). There were 22,000 households, of which 37.1% had children under the age of 18 living with them, 48.3% were married couples living together, 12.7% had a female householder with no husband present, 5.1% had a male householder with no wife present, and 33.9% were non-families. 26.7% of all households were made up of individuals, and 7.5% had someone living alone who
4292-475: The population grew, with homes spreading throughout the area, Gaithersburg began taking on a suburban and semi-urban feel, leaving its farming roots behind. During the late 1990s and 2000s, it had become one of the most economically and ethnically diverse areas in the Washington, D.C. Metropolitan Area as well as the State of Maryland , with people from all walks of life calling Gaithersburg home. This can be seen in
4366-422: The size, shape, and physical properties of the earth; and to aid the space program through the precise navigational patterns of orbiting satellites. The Gaithersburg station operated until 1982 when computerization rendered the manual observation obsolete. In 1968, Gaithersburg was upgraded from a town to a city. Gaithersburg remained a predominantly rural farm town until the 1970s when more construction began. As
4440-494: The subject of much speculation in April 2007 leading to pipeline-boosting collaboration and acquisition activities. A few days later AstraZeneca acquired US company MedImmune for about US$ 15.2 billion to gain flu vaccines and an anti-viral treatment for infants; AstraZeneca subsequently consolidated all of its biologics operations into a dedicated biologics division called MedImmune. In 2010, AstraZeneca acquired Novexel Corp, an antibiotics discovery company formed in 2004 as
4514-477: The top employers in the city are: Gaithersburg also receives significant income from its conference organization platform including prominent conferences such as the CHI 84 conference. Patton Electronics was founded in Gaithersburg during 1984. Gaithersburg has an elected, five-member City Council, which serves as the legislative body of the city. The mayor, who is also elected, serves as non-voting president of
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#17327811861944588-454: The town was officially incorporated as the Town of Gaithersburg. Gaithersburg boomed during the late 19th century and churches, schools, a mill, grain elevators , stores, and hotels were built. Much of this development focused around the railroad station. In 1899, Gaithersburg was selected as one of six global locations for the construction of an International Latitude Observatory as part of
4662-407: The town. The racial makeup of the town was 33% White, 13% Black, 15% Asian, and 1% from other races. Hispanic people of any race were 36% of the population. The median household income was 95,453, and 6% of people were under the poverty line. The average time to work was 30 minutes, 57% of people drove alone, 11% carpooled, 8% took public transit, 1% biked, 2% walked and 20% work from home. As of
4736-595: The transaction the company will gain commercial rights to Acerta's irreversible oral Bruton's tyrosine kinase inhibitor, acalabrutinib (ACP-196), which is currently in Phase III development for B-cell blood cancers and in Phase I or II clinical trials in solid tumours. In 2015, it was the eighth-largest drug company in the world based on sales revenue. In July 2017, the company's CEO Pascal Soriot said that Brexit would not affect its commitment to its current plans in
4810-476: The treatment of a number of autoimmune diseases, which could generate up to US$ 122.5 million for Orca. The company also announced its plan to spend US$ 40 million creating a new subsidiary focused on small molecule anti-infectives – primarily in the research of the gyrase inhibitor, AZD0914 , which is currently in Phase II for the treatment of gonorrhea . The company underwrote twenty out of thirty-two seats of
4884-459: The world based on sales and ranked seventh based on R&D investment. In January EVP Pam Cheng stated that AstraZeneca has ignited startup of duplicate QA testing facility in Sweden and has initiated hiring in Sweden. In February 2018, AstraZeneca announced it was spinning off six early-stage experimental drugs into a new biotechnology company, known as Viela Bio, valued at US$ 250 million. On 6 December 2018, AstraZeneca purchased nearly 8% of
4958-498: Was 65 years of age or older. The average household size was 2.70 and the average family size was 3.24. The median age in the city was 35.1 years. 24.2% of residents were under the age of 18; 7.9% were between the ages of 18 and 24; 33.8% were from 25 to 44; 24.6% were from 45 to 64; and 9.5% were 65 years of age or older. The gender makeup of the city was 48.6% male and 51.4% females. As of the census of 2000, there were 52,613 people, 19,621 households, and 12,577 families residing in
5032-460: Was announced that the company would acquire LogicBio Therapeutics, which was active in clinical-stage genomic medicine . In November 2022, it was announced AstraZeneca had acquired the Amsterdam -headquartered clinical-stage biotechnology company, Neogene Therapeutics. In January, AstraZeneca announced it would acquire CinCor Pharma for $ 1.8 billion. In November 2023, AstraZeneca launched
5106-408: Was approved in Japan as monotherapy for non-small cell lung cancer . On 3 January 2004 Dr Robert Nolan, a former director of AstraZeneca, formed the management team of ZI Medical. In 2005, the company acquired KuDOS Pharmaceuticals, a UK biotech company, for £120 million. and entered into an anti-cancer collaboration agreement with Astex It also announced that it had become a Diamond Member of
5180-427: Was back in the number one spot for diversity in the U.S. Gaithersburg was settled in 1765 as a small agricultural settlement known as Log Town near the present day Summit Hall on Ralph Crabb's 1725 land grant "Deer Park". The northern portion of the land grant was purchased by Henry Brookes, and he built his brick home "Montpelier" there, starting first with a log cabin in 1780/3. This 1,000-acre tract became part of
5254-409: Was foreign-born. There were 19,621 households, out of which 34.8% had children under the age of 18 living with them, 48.6% were married couples living together, 11.2% had a female householder with no husband present, and 35.9% were non-families. 27.8% of all households were made up of individuals, and 7.2% had someone living alone who was 65 years of age or older. The average household size was 2.65 and
5328-460: Was formed by a large group of doctors and apothecaries in Södertälje. Throughout the twentieth century, it grew into the largest pharmaceutical company in Sweden. Its British counterpart, Zeneca PLC was formed in 1993 when ICI divested its pharmaceuticals businesses; Astra AB and Zeneca PLC merged six years later, with the chosen headquarters in the United Kingdom. AstraZeneca's primary listing
5402-511: Was known to inhabitants as Gaithersburg. The Forest Oak Post Office, named for a large tree in the town, was located in Gaither's store in 1851. On July 10, 1864, using the route of present-day 355, over 10,000 Confederate troops camped overnight in the area, including the present Bohrer Park, after a one-day march from Frederick after the Battle of Monocacy . The next day the troops continued towards Washington in an unsuccessful attempt to take
5476-498: Was the precursor to I-270 and follows a parallel route. It now serves as the main commercial roadway through Gaithersburg and neighboring communities. Other state highways serving Gaithersburg include Maryland Route 117 , Maryland Route 119 and Maryland Route 124 . Maryland Route 28 passes just outside the Gaithersburg corporate limits. Gaithersburg is connected to the Washington Metro via Shady Grove station , which
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