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Uganda Cancer Institute

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Uganda Cancer Institute ( UCI ) is a public, specialized, tertiary care medical facility owned by the Uganda Ministry of Health . It is designated as East Africa's Centre of Excellence in Oncology . In collaboration with Makerere University College of Health Sciences , UCI plans to start offering master's degrees, doctoral programs and post-doctoral fellowships in oncology care.

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29-689: The facility is located along Upper Mulago Hill Road, on Mulago Hill , in the Kawempe Division of Kampala , about 4.5 kilometres (2.8 mi) north of the central business district of the city. UCI is a cancer treatment, research, and teaching center, affiliated with the Makerere University School of Medicine and with the Mulago National Referral Hospital , the teaching hospital for the medical school. UCI maintains an inpatient facility with

58-552: A $ 265 million initial public offering in 2014, was started based on inventions made at the center. As of 2015, about twenty companies had been started based on center inventions since 1975, including Immunex and Icos . The institute's main campus consists of 13 buildings that are on fifteen acres (6.1 ha) in the South Lake Union neighborhood of Seattle. In 1987, the center began exploring possible new homes to replace its 9-building campus on First Hill that it

87-604: A capacity of 80 beds. It attends to an average of about 200 patients daily. In October 2011, ground was broken for a three-story, integrated cancer training, research, and treatment facility, measuring nearly 16,700 square feet (1,550 m). The new building, called the "UCI-Fred Hutch Cancer Centre," is jointly operated by the UCI and the Fred Hutchinson Cancer Center in Seattle, Washington , US as part of

116-634: A new 360-bed inpatient facility was under construction to accommodate an increased influx of patients. Since the beginning of 2023, there has been a significant increase in private patients, who previously were seeking cancer care outside the country. The patient influx is attributed to better services and care, including the availability of oncology medications, the availability of a medical LINAC machine to precisely guide radiation therapy and an increased number of oncology physicians and nurses. The international research centers with collaborative projects with Uganda Cancer Institute include, but are not limited to

145-664: Is Mulago Hospital . Built in 1917, Old Mulago Hospital merged with the New Mulago Hospital in 1960 to form a giant complex that is the national referral hospital . The complex also houses Makerere University Medical School ." At the lower end of the hill about 2 kilometres (1.2 mi) from the hospital complex, are the Uganda Museum and headquarters of the Uganda Wildlife Authority at Kamwookya . The British High Commission office and

174-629: Is a market at Kamwookya, between Kololo Hill and Mulago Hill. The Uganda Electricity Transmission Company Limited maintains a large electricity sub-station at Mulago, which distributes power to the northern part of the city, including Makerere University , the Mulago Hospital Complex, Old Kampala and most of Nakasero Hill. 00°20′33″N 32°34′37″E  /  0.34250°N 32.57694°E  / 0.34250; 32.57694 Fred Hutchinson Cancer Research Center The Fred Hutchinson Cancer Center , formerly known as

203-511: Is expected in Uganda in December 2023. The following medical researchers have served as director of UCI since its founding in 1967: Mulago Hill Mulago is a hill in north-central Kampala , the capital city of Uganda . The hill rises 4,134 feet (1,260 m) above sea level. The name also applies to the neighborhoods that sit on this hill. Mulago is in Kawempe Division , one of

232-718: Is part of a two-year renovation plan that UCI is implementing at a cost of US$ 49 million. In March 2016, the "Cobalt-60 Teletherapy " unit at UCI, which had been in use for the previous 20 years, broke down. Efforts to acquire a replacement unit are underway, with installation expected in 2018. In the interim, the Uganda Ministry of Health has arranged with the Aga Khan University Hospital in Nairobi, Kenya , to offer teletherapy to some Ugandan patients. A brand new teletherapy machine, manufactured in

261-618: The Czech Republic , arrived in Uganda in August 2017. The machine was purchased at a cost of €642,000 (more than UShs2.7 billion), contributed by the government of Uganda and the International Atomic Energy Agency (IAEA). It is expected that installation of the new machine will take at least one month. Following installation and testing of the new machine, the institution started treating patients using

290-647: The Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch , is a cancer research institute established in 1975 in Seattle , Washington . The center grew out of the Pacific Northwest Research Foundation , founded in 1956 by William B. Hutchinson (1909–1997). The Foundation was dedicated to the study of heart surgery , cancer, and diseases of the endocrine system . Hutchinson's younger brother Fred (1919–1964)

319-642: The National Cancer Institute (NCI) in Bethesda, Maryland ." In 1972, following the expulsion of Ugandan Asians by dictator Idi Amin , nearly all of NCI's scientists left. "Professor Charles Olweny , a Uganda researcher, interrupted his studies at NCI in the US and returned to become the first Ugandan director of UCI. In 1982, following the overthrow of Idi Amin , Olweny was forced to leave Uganda for security reasons, leaving leadership of UCI in

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348-621: The Nobel Prize in Physiology or Medicine : The center is active in technology transfer . In 2013, it was one of the top ten biomedical research institutions in the field (excluding universities); it made 18 new deals with companies to develop inventions made at the center, and earned $ 10,684,882 in income from past deals it had signed. Most notably, Juno Therapeutics , a company developing CAR-T immunotherapy for cancer and that raised $ 314 million in venture capital investments and had

377-544: The 1980s and early 1990s, patients were not informed about all the risks of the study, nor about the study doctors' financial interest in study outcome. The paper also alleged that this financial interest may have contributed to the doctors' failure to halt the studies despite evidence that patients were dying sooner and more frequently than expected. In response, the center formed a panel of independent experts to review its existing research practices, leading to adoption of new conflict-of-interest rules. In 2010 Lawrence Corey

406-598: The Fred Hutchinson Cancer Research Center became independent 1972 and its building opened three years later in 1975. The center was named an NCI-designated Comprehensive Cancer Center in 1976. In 1998, the center formed the Seattle Cancer Care Alliance (SCCA), a separate nonprofit corporation, with University of Washington School of Medicine (UW Medicine), and Seattle Children's . This solidified

435-540: The High Commission office of Rwanda are both located in neighboring Kamwookya . The hill is, however, dominated by hospital related activities that include: The headquarters of the Uganda Ministry of Health is located at Wandegeya , in the valley between Nakasero Hill and Mulago Hill. There is a small residential area on Mulago Hill, overlooking the Uganda National Museum. Also, there

464-625: The Lymphoma Treatment Center, to treat childhood lymphomas, predominantly Burkitt's lymphoma , the most common childhood lymphoma in Uganda and endemic to tropical Africa . In 1969, UCI expanded to a total of 40 beds, when the Solid Tumor Center was added to focus research on Kaposi's sarcoma and liver cancer . "During the 1960s and early 1970s, UCI was a leading international medical research center, in its areas of specialization. UCI established collaboration with

493-648: The UCI-Fred Hutch Collaboration. In May 2015, the completed facility opened and began attending to patients. In November 2020, the UCI-Fred Hutch Collaboration completed the construction of the new ground-level of the facility, which houses administrative offices and a biorepository. As of August 2024, it was reported that over a 5-year period, an average of 35,968 new cancer cases were diagnosed in Uganda every year. Also every year, on average, 24,629 people died from their cancer diagnoses. Another 77,028 patients, on average, live with their cancers in

522-773: The Uganda Cancer Institute. It received additional funding in October 2009, when the United States Agency for International Development awarded a US$ 500,000 grant to the Fred Hutchinson Cancer Center to aid in the construction of the first United States cancer clinic and medical-training facility in Africa. In 2016, the institute installed a "Flexitron Cobalt-60 High Dose Rate" brachytherapy system from Elekta . The system

551-646: The center's reach into clinical care and was essential for it retaining its NCI comprehensive center designation; the designation was extended to the center's consortium including the SCCA in 2003. SCCA's outpatient clinic first opened in January 2001. In 2001, The Seattle Times published a series of articles alleging that investigators at the center (including the center's co-founder E. Donnall Thomas ) were conducting unethical clinical studies on cancer patients. The paper alleged that in two cancer studies conducted in

580-409: The country. Between 1 January 2017 and 31 December 2022, the leading cancers in women in Uganda were (1) Cervical cancer (2) Breast cancer (3) Stomach cancer (4) Esophageal cancer and (5) Liver cancer . During the same time, the leading cancers in men in Uganda were (1) Prostate cancer (2) Kaposi's sarcoma (3) Liver cancer and (4) Lymphoma . UCI was founded in 1967 with twenty beds, as

609-483: The five administrative divisions of Kampala. It is approximately 4 kilometres (2.5 mi), by road, north of the city's central business district. The coordinates of Mulago are 0°20'33.0"N, 32°34'37.0"E (Latitude:0.342508; Longitude:32.576959). "Mulago was derived from the Ganda word 'omulago', a type of medicine, kept on this hill that was used by King Suna II for protection against spirits. The landmark on this hill

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638-517: The following: The Uganda Program on Cancer and Infectious Diseases (UPCID), established in 2004, is a joint program between Fred Hutchinson Cancer Research Center in Seattle and the Uganda Cancer Institute. The program works to understand and treat infection-related cancers in the United States and abroad. The collaboration was founded by Corey Casper, a physician-scientist at the Fred Hutchinson Cancer Center and Jackson Orem , director of

667-525: The hands of Professor Edward Katongole-Mbidde . When Katongole-Mbidde left UCI to become the director at the Uganda Virus Research Institute in 1995, Dr. Jackson Orem took over the helm at UCI. Between 2011 and 2015, the bed capacity at the institute was increased to 80. As of September 2023, UCI's bed capacity was reported to be 100 in-patient beds, of which 75 are general and 25 are for private, paying patients. At that time,

696-477: The new machine. Also in 2018, Samta Memorial Foundation, an Indian-based non-government organization donated a mobile mammography unit that is now in use at UCI. In October 2023, Madhusudan Agrawal, Uganda's honorary council to India, based in Mumbai donated a second mobile cancer screening van to UCI. This is in addition to the mobile mammography van donated by the same person in 2018. The new diagnostic vehicle

725-582: The new telepathy machine on 4 December 2017 and officially commissioned it on 19 January 2018. In February 2020, UCI commissioned a new Bhabhatron II Cancer Therapy Machine, donated to Uganda by the government of India . This machine, which also uses Cobalt 60 as the source of radiation will supplement the one acquired two years earlier from the Czech Republic. The new unit was installed by Indian technicians. A group of Ugandan oncologists and technicians were earlier sent to India to train on how to operate

754-464: The organization adopt its longtime local nickname, "Fred Hutch", as its official name as part of a rebranding. On April 1, 2022, Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance (SCCA) merged to form Fred Hutchinson Cancer Center , a unified adult cancer research and care center that is clinically integrated with University of Washington (UW) Medicine and UW Medicine's cancer program. The center has employed three recipients of

783-713: Was a major league pitcher and manager who died of lung cancer at age 45. The next year, William Hutchinson established the Fred Hutchinson Cancer Research Center as a division of the Pacific Northwest Research Foundation. In 1972, with the help of Senator Warren G. Magnuson , PNRF received federal funding under the National Cancer Act of 1971 to create in Seattle one of the 15 new NCI-designated Cancer Centers aimed at conducting basic research called for under 1971 Act;

812-443: Was appointed as the fourth President, following the retirement of Lee Hartwell . He was followed by Gary Gilliland in 2015 as president, who led the institute until 2020. Under his leadership the center announced that it would expand into the former Lake Union steam plant, which previously housed ZymoGenetics . The move was completed in October 2020. In February 2020, Thomas J. Lynch Jr. took over as director. The year 2014 saw

841-526: Was set to outgrow. A site in the South Lake Union neighborhood, envisioned by the city as a future high-tech and biotechnology hub, was chosen in September 1988 after a deal to move to Fremont fell through earlier that year. The first phase of the campus, designed by firm Zimmer Gunsul Frasca Partnership , began construction in 1991 and opened on June 1, 1993, in a ceremony that included

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