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Uterus

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The uterus (from Latin uterus , pl. : uteri or uteruses) or womb ( / w uː m / ) is the organ in the reproductive system of most female mammals , including humans, that accommodates the embryonic and fetal development of one or more fertilized eggs until birth . The uterus is a hormone -responsive sex organ that contains glands in its lining that secrete uterine milk for embryonic nourishment. (The term uterus is also applied to analogous structures in some non-mammalian animals.)

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29-406: In the human, the lower end of the uterus is a narrow part known as the isthmus that connects to the cervix , the anterior gateway leading to the vagina . The upper end, the body of the uterus, is connected to the fallopian tubes at the uterine horns ; the rounded part, the fundus, is above the openings to the fallopian tubes. The connection of the uterine cavity with a fallopian tube is called

58-541: A choriovitelline placenta (which can be thought of as something between a monotreme egg and a "true" placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream. However, bandicoots also have a rudimentary chorioallantoic placenta, similar to those of placental mammals. The fetus usually develops fully in placental mammals and only partially in marsupials including kangaroos and opossums . In marsupials,

87-420: A female and usually male fetus, and in placental mammals, they may partially or completely fuse into a single uterus depending on the species. In many species with two uteri, only one is functional. Humans and other higher primates such as chimpanzees, usually have a single completely fused uterus, although in some individuals, the uteri may not have completely fused. Uterine isthmus The uterine isthmus

116-485: Is broken down, shed, and restored in anticipation of the next menstrual cycle. The average bleeding duration during menses is 5-7 days after which the menstrual cycle begins again. During pregnancy , the growth rate of the fetus can be assessed by measuring the fundal height . Some pathological states include: Uterine malformations are mainly congenital malformations , and include uterus didelphys , bicornuate uterus and septate uterus . Congenital absence of

145-433: Is covered by a sheet-like fold of peritoneum, the broad ligament . The uterus has three layers, which together form the uterine wall . From innermost to outermost, these layers are the endometrium , myometrium , and perimetrium . The endometrium is the inner epithelial layer , along with its mucous membrane , of the mammalian uterus. It has a basal layer and a functional layer; the functional layer thickens and then

174-405: Is known as the junctional zone , which becomes thickened in adenomyosis . The perimetrium is a serous layer of visceral peritoneum . It covers the outer surface of the uterus. Surrounding the uterus is a layer or band of fibrous and fatty connective tissue called the parametrium that connects the uterus to other tissues of the pelvis. Commensal and mutualistic organisms are present in

203-436: Is shed during the menstrual cycle or estrous cycle . During pregnancy , the uterine glands and blood vessels in the endometrium further increase in size and number and form the decidua . Vascular spaces fuse and become interconnected, forming the placenta , which supplies oxygen and nutrition to the embryo and fetus . The myometrium of the uterus mostly consists of smooth muscle . The innermost layer of myometrium

232-400: Is the fibrous and fatty connective tissue that surrounds the uterus . This tissue separates the supravaginal portion of the cervix from the bladder . The parametrium lies in front of the cervix and extends laterally between the layers of the broad ligaments . It connects the uterus to other tissues in the pelvis . It is different from the perimetrium , which is the outermost layer of

261-427: Is the inferior-posterior part of uterus , on its cervical end — here, the uterine muscle ( myometrium ) is narrower and thinner. It connects the body and cervix. The uterine isthmus can become more compressibile in pregnancy, which is a finding known as Hegar's sign . This article related to the genitourinary system is a stub . You can help Misplaced Pages by expanding it . Parametrium The parametrium

290-435: Is the most commonly performed gynecological surgical procedure . Uterus transplantations have been successfully carried out in a number of countries. The transplant is intended to be temporary – recipients will have to undergo a hysterectomy after one or two successful pregnancies. This is done to avoid the need to take immunosuppressive drugs for life with a consequent increased risk of infection. The procedure remains

319-612: The fallopian tubes and the uterus. In humans, the lower segments of the two ducts fuse to form a single uterus; in cases of uterine malformations this fusion may be disturbed. The different uterine morphologies among the mammals are due to varying degrees of fusion of the Müllerian ducts. Various congenital conditions of the uterus can develop in utero . Though uncommon, some of these are didelphic uterus , bicornate uterus and others. See also List of related male and female reproductive organs . The primary reproductive function of

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348-419: The fundus – the uppermost rounded portion of the uterus above the openings of the fallopian tubes , the body , the cervix , and the cervical canal . The cervix protrudes into the vagina . The uterus is held in position within the pelvis by ligaments , which are part of the endopelvic fascia . These ligaments include the pubocervical ligaments , the cardinal ligaments , and the uterosacral ligaments . It

377-417: The interspinal line . The uterus is mobile and moves posteriorly under the pressure of a full bladder, or anteriorly under the pressure of a full rectum. If both are full, it moves upwards. Increased intra-abdominal pressure pushes it downwards. The mobility is conferred to it by a musculo-fibrous apparatus that consists of suspensory and sustentacular parts. Under normal circumstances, the suspensory part keeps

406-483: The paramesonephric ducts , which fuse into the single organ known as a simplex uterus. The uterus has different forms in many other animals and in some it exists as two separate uteri known as a duplex uterus. In medicine and related professions, the term uterus is consistently used, while the Germanic -derived term womb is commonly used in everyday contexts. Events occurring within the uterus are described with

435-424: The platypus and the echidnas , either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization . Marsupials have two uteri, each of which connect to a lateral vagina and both use a third, middle "vagina", which functions as the birth canal. Marsupial embryos form

464-413: The uterotubal junction . The fertilized egg is carried to the uterus along the fallopian tube. It will have divided on its journey to form a blastocyst that will implant itself into the lining of the uterus – the endometrium , where it will receive nutrients and develop into the embryo proper, and later fetus , for the duration of the pregnancy . In the human embryo , the uterus develops from

493-506: The human uterus is to prepare for the implantation of a zygote , a fertilized ovum , and maintenance of pregnancy if implantation occurs. Traveling along the fallopian tube on its way to the uterine cavity, the zygote divides mitotically to become a blastocyst , which ultimately attaches to the uterine wall and implants into the endometrium . The placenta later develops to nourish the embryo, which grows through embryonic and fetal development until childbirth . During this process,

522-406: The human uterus lies in anteversion and anteflexion. In most women, the long axis of the uterus is bent forward on the long axis of the vagina, against the urinary bladder. This position is referred to as anteversion of the uterus. Furthermore, the long axis of the body of the uterus is bent forward at the level of the internal os with the long axis of the cervix. This position is termed anteflexion of

551-413: The last resort: it is as of 2023, a relatively new and somewhat experimental procedure, performed only by certain specialist surgeons in select centres, it is expensive and unlikely to be covered by insurance, and it involves risk of infection and organ rejection. Some ethics specialists consider the risks to a live donor too great, and some find the entire procedure ethically questionable, especially since

580-437: The term in utero . In humans, the uterus is located within the pelvic region immediately behind and almost overlying the bladder , and in front of the sigmoid colon . The human uterus is pear-shaped and about 7.6 cm (3.0 in) long, 4.5 cm (1.8 in) broad (side to side), and 3.0 cm (1.2 in) thick. A typical adult uterus weighs about 60 grams. The uterus can be divided anatomically into four regions:

609-460: The transplant is not a life-saving procedure. Most animals that lay eggs , such as birds and reptiles , including most ovoviviparous species, have an oviduct instead of a uterus. However, recent research into the biology of the viviparous (not merely ovoviviparous ) skink Trachylepis ivensi has revealed development of a very close analogue to eutherian mammalian placental development. In monotremes , mammals which lay eggs, namely

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638-414: The uterus and form the uterine microbiome . The uterus is primarily supported by the pelvic diaphragm , perineal body , and urogenital diaphragm . Secondarily, it is supported by ligaments, including the peritoneal ligament and the broad ligament of uterus . The uterus is held in place by several peritoneal ligaments, of which the following are the most important (there are two of each): Normally,

667-427: The uterus forms as a duplex organ of two uteri. In monotremes such as the platypus , the uterus is duplex and rather than nurturing the embryo, secretes the shell around the egg. It is essentially identical with the shell gland of birds and reptiles, with which the uterus is homologous . In mammals, the four main forms of the uterus are: duplex, bipartite, bicornuate and simplex. Two uteri usually form initially in

696-492: The uterus from anastomosis of these two arteries. Afferent nerves supplying the uterus are T11 and T12 . Sympathetic supply is from the hypogastric plexus and the ovarian plexus . Parasympathetic supply is from the S2, S3 and S4 nerves. Bilateral Müllerian ducts form during early human fetal life. In males, anti-Müllerian hormone (AMH) secreted from the testes leads to the ducts' regression. In females, these ducts give rise to

725-419: The uterus grows to accommodate the growing fetus. When normal labor begins, the uterus forcefully contracts as the cervix dilates, which results in delivery of the infant. In the absence of pregnancy, menstruation occurs. The withdrawal of female sex hormones, estrogen and progesterone , which occurs in the absence of fertilization, triggers the shedding of the functional layer of the endometrium. This layer

754-447: The uterus in anteflexion and anteversion (in 90% of women) and keeps it "floating" in the pelvis. The meanings of these terms are described below: The sustentacular part supports the pelvic organs and comprises the larger pelvic diaphragm in the back and the smaller urogenital diaphragm in the front. The pathological changes of the position of the uterus are: In cases where the uterus is "tipped", also known as retroverted uterus ,

783-415: The uterus is known as Müllerian agenesis . A hysterectomy is the surgical removal of the uterus, which may be carried out for a number of reasons including the ridding of tumours both benign and malignant . A complete hysterectomy involves the removal of the body, fundus, and cervix of the uterus. A partial hysterectomy may just involve the removal of the uterine body while leaving the cervix intact. It

812-411: The uterus. The uterus assumes an anteverted position in 50% of women, a retroverted position in 25% of women, and a midposed position in the remaining 25% of women. The uterus is located in the middle of the pelvic cavity, in the frontal plane (due to the broad ligament of the uterus ). The fundus does not extend above the linea terminalis , while the vaginal part of the cervix does not extend below

841-414: The woman may have symptoms of pain during sexual intercourse, pelvic pain during menstruation, minor incontinence, urinary tract infections, fertility difficulties, and difficulty using tampons. A pelvic examination by a doctor can determine if a uterus is tipped. The human uterus is supplied by arterial blood both from the uterine artery and the ovarian artery . Another anastomotic branch may also supply

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