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Legal death is the recognition under the law of a particular jurisdiction that a person is no longer alive. In most cases, a doctor's declaration of death (variously called) or the identification of a corpse is a legal requirement for such recognition. A person who has been missing for a sufficiently long period of time (typically at least several years) may be presumed or declared legally dead , usually by a court . When a death has been registered in a civil registry , a death certificate may be issued. Such death certificate may be required in a number of legal situations, such as applying for probate , claiming some benefits, or making an insurance claim .

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87-577: A biochron (from the Greek bios , life ; and khronos , time ) is the length of time represented by a biostratigraphic zone . Biochrons are named after characteristic fossil organisms or taxa that characterise that interval in time. This paleontology article is a stub . You can help Misplaced Pages by expanding it . Life Life on Earth: Life is a quality that distinguishes matter that has biological processes , such as signaling and self-sustaining processes, from matter that does not. It

174-457: A Romanian man living in Turkey, lost contact with his family. His wife had a court declare him dead in 2016, after having no contact with him since July 1999, shortly before a major earthquake in Turkey . His wife assumed that he had died in the earthquake. In 2013, an Ohio man named Donald E. Miller Jr. who was declared legally dead in 1994 resurfaced and sued to be declared alive. However,

261-428: A coroner or appoint a medical examiner , depending on jurisdiction, to both determine manner and cause of death, and if necessary, identify bodies when their identities are unknown. Manner of death is usually classified as natural , accidental , homicide , suicide , pending or undetermined. A soldier is often listed as killed in action if the death was during military service. There are legal implications to all of

348-420: A double helix . The two DNA strands are known as polynucleotides since they are composed of simpler units called nucleotides . Each nucleotide is composed of a nitrogen-containing nucleobase —either cytosine (C), guanine (G), adenine (A), or thymine (T)—as well as a sugar called deoxyribose and a phosphate group . The nucleotides are joined to one another in a chain by covalent bonds between

435-420: A living systems theory viewpoint that does not necessarily depend on molecular chemistry. One systemic definition of life is that living things are self-organizing and autopoietic (self-producing). Variations of this include Stuart Kauffman 's definition as an autonomous agent or a multi-agent system capable of reproducing itself, and of completing at least one thermodynamic work cycle . This definition

522-428: A nucleus and other membrane-bound organelles , although they have circular DNA and ribosomes . Bacteria and Archaea are two domains of prokaryotes. The other primary type is the eukaryote cell, which has a distinct nucleus bound by a nuclear membrane and membrane-bound organelles, including mitochondria , chloroplasts , lysosomes , rough and smooth endoplasmic reticulum , and vacuoles . In addition, their DNA

609-403: A universal common ancestor . This evolved into all the species that exist now, by way of many extinct species, some of which have left traces as fossils . Attempts to classify living things, too, began with Aristotle . Modern classification began with Carl Linnaeus 's system of binomial nomenclature in the 1740s. Living things are composed of biochemical molecules , formed mainly from

696-407: A common origin. All life forms require certain core chemical elements for their biochemical functioning. These include carbon , hydrogen , nitrogen , oxygen , phosphorus , and sulfur —the elemental macronutrients for all organisms. Together these make up nucleic acids , proteins and lipids , the bulk of living matter. Five of these six elements comprise the chemical components of DNA,

783-528: A consequence of these microbial activities, the physical-chemical environment on Earth has been changing on a geologic time scale , thereby affecting the path of evolution of subsequent life. For example, the release of molecular oxygen by cyanobacteria as a by-product of photosynthesis induced global changes in the Earth's environment. Because oxygen was toxic to most life on Earth at the time, this posed novel evolutionary challenges, and ultimately resulted in

870-500: A court battle to be declared alive in March of 2018, but the decision was reversed three months later when the courts declared him alive. Donald E. Miller Jr. remains legally dead because the state of Ohio has no legal means for reversing a declaration of death, and Jeanne Pouchain of France was still fighting to be legally recognized as alive in 2021. Determining manner of death often has important legal implications. Governments elect

957-656: A few core chemical elements . All living things contain two types of large molecule, proteins and nucleic acids , the latter usually both DNA and RNA : these carry the information needed by each species, including the instructions to make each type of protein. The proteins, in turn, serve as the machinery which carries out the many chemical processes of life. The cell is the structural and functional unit of life. Smaller organisms, including prokaryotes (bacteria and archaea ), consist of small single cells. Larger organisms , mainly eukaryotes , can consist of single cells or may be multicellular with more complex structure. Life

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1044-442: A host cell to make new products. Virus self-assembly within host cells has implications for the study of the origin of life , as it may support the hypothesis that life could have started as self-assembling organic molecules . Some of the earliest theories of life were materialist, holding that all that exists is matter, and that life is merely a complex form or arrangement of matter. Empedocles (430 BC) argued that everything in

1131-515: A legal declaration of death is fraudulent. Several people have faked their own deaths for various reasons. The most common reasons for this are to collect insurance money , to avoid capture by police or to avoid paying debts. At times, people declare other people dead for their own benefit. For instance, in India, several people have been falsely and fraudulently declared dead by family members wishing to steal land and other property. The best known

1218-472: A matter of debate; viruses lack characteristics of life such as cell membranes, metabolism and the ability to grow or respond to their environments. Viruses have been classed into "species" based on their genetics , but many aspects of such a classification remain controversial. The original Linnaean system has been modified many times, for example as follows: The attempt to organise the Eukaryotes into

1305-535: A month in a simulated Martian environment . Beyond the Solar System, the region around another main-sequence star that could support Earth-like life on an Earth-like planet is known as the habitable zone . The inner and outer radii of this zone vary with the luminosity of the star, as does the time interval during which the zone survives. Stars more massive than the Sun have a larger habitable zone, but remain on

1392-532: A person. In jurisdictions that practiced civil death, it was legal to kill such a person, since they were not legally recognized as alive anymore, and therefore their killing not considered a murder. Reversing an incorrect declaration of death can be a time-consuming and difficult process. Whether a victim of fraud or an honest error, it often takes many years to reverse a fraudulent death declaration, and at times it never happens. Bihari didn't get his declaration of death reversed until 1994, 19 years later. Reliu lost

1479-447: A physician determines that efforts to restart a stopped heart during cardiac arrest are futile, or that no attempt should be made to restart a stopped heart, such as when there is a Do Not Resuscitate (DNR) order. In the latter case, irreversible is understood to mean that heartbeat and breathing cannot return on their own and will not be restored by medical intervention. Brain death determinations are made in cases where breathing

1566-400: A resurgence of interest in the work of Russell, Barge and colleagues. Hylomorphism is a theory first expressed by the Greek philosopher Aristotle (322 BC). The application of hylomorphism to biology was important to Aristotle, and biology is extensively covered in his extant writings . In this view, everything in the material universe has both matter and form, and the form of a living thing

1653-809: A set of 355 genes from the last universal common ancestor was tentatively identified. The biosphere is postulated to have developed, from the origin of life onwards, at least some 3.5 billion years ago. The earliest evidence for life on Earth includes biogenic graphite found in 3.7 billion-year-old metasedimentary rocks from Western Greenland and microbial mat fossils found in 3.48 billion-year-old sandstone from Western Australia . More recently, in 2015, "remains of biotic life " were found in 4.1 billion-year-old rocks in Western Australia. In 2017, putative fossilised microorganisms (or microfossils ) were announced to have been discovered in hydrothermal vent precipitates in

1740-619: A short period Linnaeus had classified them in the taxon Vermes in Animalia, but later placed them back in Plantae. Herbert Copeland classified the Fungi in his Protoctista , including them with single-celled organisms and thus partially avoiding the problem but acknowledging their special status. The problem was eventually solved by Whittaker , when he gave them their own kingdom in his five-kingdom system . Evolutionary history shows that

1827-467: A small number of kingdoms has been challenged. The Protozoa do not form a clade or natural grouping, and nor do the Chromista (Chromalveolata). The ability to sequence large numbers of complete genomes has allowed biologists to take a metagenomic view of the phylogeny of the whole tree of life . This has led to the realisation that the majority of living things are bacteria, and that all have

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1914-408: A thousand years. In the late 1740s, Carl Linnaeus introduced his system of binomial nomenclature for the classification of species. Linnaeus attempted to improve the composition and reduce the length of the previously used many-worded names by abolishing unnecessary rhetoric, introducing new descriptive terms and precisely defining their meaning. The fungi were originally treated as plants. For

2001-488: Is Lal Bihari , who was fraudulently declared dead by family members, and was legally dead between 1975 and 1994. Bihari founded the Association of Dead People to help others in similar situations. Historically, those who have committed crimes or other wrongs against the state have been declared legally dead despite being obviously alive. This is known as civil death . Such a person loses all rights normally granted to

2088-423: Is supported by machines . Brain death is determined by there being no signs of brain function during neurological examination of a person with a beating heart. Confirmatory tests document either no blood flow to the brain , or no brain electrical activity in absence of factors known to produce reversible loss of brain function. Unlike cardiopulmonary death which sometimes involves a decision not to resuscitate

2175-473: Is a mechanistic explanation for the origin of species by means of natural selection . At the beginning of the 20th century Stéphane Leduc (1853–1939) promoted the idea that biological processes could be understood in terms of physics and chemistry, and that their growth resembled that of inorganic crystals immersed in solutions of sodium silicate. His ideas, set out in his book La biologie synthétique , were widely dismissed during his lifetime, but has incurred

2262-561: Is about 4.54 billion years . Life on Earth has existed for at least 3.5 billion years, with the oldest physical traces of life dating back 3.7 billion years. Estimates from molecular clocks, as summarised in the TimeTree public database, place the origin of life around 4.0 billion years ago. Hypotheses on the origin of life attempt to explain the formation of a universal common ancestor from simple organic molecules via pre-cellular life to protocells and metabolism. In 2016,

2349-558: Is capable of forming the various specialised cells that form the adult organism. This specialisation allows multicellular organisms to exploit resources more efficiently than single cells. About 800 million years ago, a minor genetic change in a single molecule, the enzyme GK-PID , may have allowed organisms to go from a single cell organism to one of many cells. Cells have evolved methods to perceive and respond to their microenvironment, thereby enhancing their adaptability. Cell signalling coordinates cellular activities, and hence governs

2436-422: Is considered the starting point of modern organic chemistry . It is of historical significance because for the first time an organic compound was produced in inorganic reactions. During the 1850s Hermann von Helmholtz , anticipated by Julius Robert von Mayer , demonstrated that no energy is lost in muscle movement, suggesting that there were no "vital forces" necessary to move a muscle. These results led to

2523-455: Is defined descriptively by the capacity for homeostasis , organisation , metabolism , growth , adaptation , response to stimuli , and reproduction . All life over time eventually reaches a state of death , and none is immortal . Many philosophical definitions of living systems have been proposed, such as self-organizing systems. Viruses in particular make definition difficult as they replicate only in host cells. Life exists all over

2610-421: Is extended by the evolution of novel functions over time. Death is the termination of all vital functions or life processes in an organism or cell. One of the challenges in defining death is in distinguishing it from life. Death would seem to refer to either the moment life ends, or when the state that follows life begins. However, determining when death has occurred is difficult, as cessation of life functions

2697-425: Is its soul (Greek psyche , Latin anima ). There are three kinds of souls: the vegetative soul of plants, which causes them to grow and decay and nourish themselves, but does not cause motion and sensation; the animal soul , which causes animals to move and feel; and the rational soul , which is the source of consciousness and reasoning, which (Aristotle believed) is found only in man. Each higher soul has all of

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2784-407: Is most likely to exist, within wide bounds of uncertainty. A "Confidence of Life Detection" scale (CoLD) for reporting evidence of life beyond Earth has been proposed. Artificial life is the simulation of any aspect of life, as through computers, robotics , or biochemistry . Synthetic biology is a new area of biotechnology that combines science and biological engineering . The common goal

2871-476: Is not only plausible, but probable or inevitable, possibly resulting in a biophysical cosmology instead of a mere physical cosmology . Other planets and moons in the Solar System and other planetary systems are being examined for evidence of having once supported simple life, and projects such as SETI are trying to detect radio transmissions from possible alien civilisations. Other locations within

2958-428: Is often not simultaneous across organ systems. Such determination, therefore, requires drawing conceptual lines between life and death. This is problematic because there is little consensus over how to define life. The nature of death has for millennia been a central concern of the world's religious traditions and of philosophical inquiry. Many religions maintain faith in either a kind of afterlife or reincarnation for

3045-580: Is only known to exist on Earth but extraterrestrial life is thought probable . Artificial life is being simulated and explored by scientists and engineers. The definition of life has long been a challenge for scientists and philosophers. This is partially because life is a process, not a substance. This is complicated by a lack of knowledge of the characteristics of living entities, if any, that may have developed outside Earth. Philosophical definitions of life have also been put forward, with similar difficulties on how to distinguish living things from

3132-485: Is organised into chromosomes . All species of large complex organisms are eukaryotes, including animals, plants and fungi, though with a wide diversity of protist microorganisms . The conventional model is that eukaryotes evolved from prokaryotes, with the main organelles of the eukaryotes forming through endosymbiosis between bacteria and the progenitor eukaryotic cell. The molecular mechanisms of cell biology are based on proteins . Most of these are synthesised by

3219-417: Is the design and construction of new biological functions and systems not found in nature. Synthetic biology includes the broad redefinition and expansion of biotechnology, with the ultimate goals of being able to design and build engineered biological systems that process information, manipulate chemicals, fabricate materials and structures, produce energy, provide food, and maintain and enhance human health and

3306-434: Is to define life as "a self-sustained chemical system capable of undergoing Darwinian evolution ", a definition adopted by a NASA committee attempting to define life for the purposes of exobiology , based on a suggestion by Carl Sagan . This definition, however, has been widely criticised because according to it, a single sexually reproducing individual is not alive as it is incapable of evolving on its own. Others take

3393-507: Is under one of two circumstances. First, if a person was known to be in mortal peril when last seen, they can often be declared dead shortly after. Examples would be the passengers of the Titanic that were not rescued after the ship sank. Second, if a person has not been seen for a certain period of time and there has been no evidence that they are alive. The amount of time that has passed varies by jurisdiction, from as little as four years in

3480-509: Is unlikely or impossible. Organisms that have a wide range of tolerance are more widely distributed than organisms with a narrow range of tolerance. To survive, some microorganisms have evolved to withstand freezing , complete desiccation , starvation , high levels of radiation exposure , and other physical or chemical challenges. These extremophile microorganisms may survive exposure to such conditions for long periods. They excel at exploiting uncommon sources of energy. Characterization of

3567-714: The International Ocean Discovery Program found unicellular life in 120 °C sediment 1.2 km below seafloor in the Nankai Trough subduction zone. According to one researcher, "You can find microbes everywhere—they're extremely adaptable to conditions, and survive wherever they are." The inert components of an ecosystem are the physical and chemical factors necessary for life—energy (sunlight or chemical energy ), water, heat, atmosphere , gravity , nutrients , and ultraviolet solar radiation protection . In most ecosystems,

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3654-504: The Nuvvuagittuq Belt of Quebec, Canada that were as old as 4.28 billion years, the oldest record of life on Earth, suggesting "an almost instantaneous emergence of life" after ocean formation 4.4 billion years ago , and not long after the formation of the Earth 4.54 billion years ago. Evolution is the change in heritable characteristics of biological populations over successive generations. It results in

3741-458: The Solar System that may host microbial life include the subsurface of Mars , the upper atmosphere of Venus , and subsurface oceans on some of the moons of the giant planets . Investigation of the tenacity and versatility of life on Earth, as well as an understanding of the molecular systems that some organisms utilise to survive such extremes, is important for the search for extraterrestrial life. For example, lichen could survive for

3828-699: The US state of Georgia to twenty years in Italy . In the UK, Lord Lucan was declared dead 25 years after he was last seen alive. There are three general categories where people may be falsely declared dead: by mistake, because of fraud, or as punishment for a crime. Sometimes people who are declared dead return and are unable to be declared alive. One study estimated that every year, the U.S. Social Security Administration declares 12,200 alive citizens as dead. Constantin Reliu,

3915-535: The United States , each state has laws for determining these two categories of death that are modeled after the Uniform Determination of Death Act . States that do not recognize "irreversible cessation of all function of the entire brain, including the brainstem" to be death include Arizona, Illinois, Iowa, Louisiana, North Carolina, and Texas. Cardiopulmonary criteria for death are met when

4002-480: The soul , or resurrection of the body at a later date. Whether or not viruses should be considered as alive is controversial. They are most often considered as just gene coding replicators rather than forms of life. They have been described as "organisms at the edge of life" because they possess genes , evolve by natural selection, and replicate by making multiple copies of themselves through self-assembly. However, viruses do not metabolise and they require

4089-467: The structure and metabolic diversity of microbial communities in such extreme environments is ongoing. The first classification of organisms was made by the Greek philosopher Aristotle (384–322 BC), who grouped living things as either plants or animals, based mainly on their ability to move. He distinguished animals with blood from animals without blood, which can be compared with the concepts of vertebrates and invertebrates respectively, and divided

4176-488: The Earth in air, water, and soil , with many ecosystems forming the biosphere . Some of these are harsh environments occupied only by extremophiles . Life has been studied since ancient times, with theories such as Empedocles 's materialism asserting that it was composed of four eternal elements , and Aristotle 's hylomorphism asserting that living things have souls and embody both form and matter. Life originated at least 3.5 billion years ago, resulting in

4263-459: The Sun-like "main sequence" of stellar evolution for a shorter time interval. Small red dwarfs have the opposite problem, with a smaller habitable zone that is subject to higher levels of magnetic activity and the effects of tidal locking from close orbits. Hence, stars in the intermediate mass range such as the Sun may have a greater likelihood for Earth-like life to develop. The location of

4350-403: The abandonment of scientific interest in vitalistic theories, especially after Eduard Buchner 's demonstration that alcoholic fermentation could occur in cell-free extracts of yeast. Nonetheless, belief still exists in pseudoscientific theories such as homoeopathy , which interprets diseases and sickness as caused by disturbances in a hypothetical vital force or life force. The age of Earth

4437-466: The appearance of new species and often the disappearance of old ones. Evolution occurs when evolutionary processes such as natural selection (including sexual selection ) and genetic drift act on genetic variation, resulting in certain characteristics increasing or decreasing in frequency within a population over successive generations. The process of evolution has given rise to biodiversity at every level of biological organisation . Fossils are

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4524-450: The attributes of the lower ones. Aristotle believed that while matter can exist without form, form cannot exist without matter, and that therefore the soul cannot exist without the body. This account is consistent with teleological explanations of life , which account for phenomena in terms of purpose or goal-directedness. Thus, the whiteness of the polar bear's coat is explained by its purpose of camouflage. The direction of causality (from

4611-399: The basic functions of multicellular organisms. Signaling between cells can occur through direct cell contact using juxtacrine signalling , or indirectly through the exchange of agents as in the endocrine system . In more complex organisms, coordination of activities can occur through a dedicated nervous system . Though life is confirmed only on Earth, many think that extraterrestrial life

4698-436: The biosphere, including soil , hot springs , inside rocks at least 19 km (12 mi) deep underground, the deepest parts of the ocean, and at least 64 km (40 mi) high in the atmosphere. For example, spores of Aspergillus niger have been detected in the mesosphere at an altitude of 48 to 77 km. Under test conditions, life forms have been observed to survive in the vacuum of space. Life forms thrive in

4785-457: The blooded animals into five groups: viviparous quadrupeds ( mammals ), oviparous quadrupeds (reptiles and amphibians ), birds, fishes and whales . The bloodless animals were divided into five groups: cephalopods , crustaceans , insects (which included the spiders, scorpions , and centipedes ), shelled animals (such as most molluscs and echinoderms ), and " zoophytes " (animals that resemble plants). This theory remained dominant for more than

4872-411: The classifications. For example, a homicide may be ruled a justifiable homicide . In nearly all jurisdictions, dead people do not have the right to own property. When a person dies, their property needs to be distributed to others in a process called probate . People can specify their wishes before they die by preparing a will and testament . If there is no will, the laws of their country determine how

4959-412: The conditions vary during the day and from one season to the next. To live in most ecosystems, then, organisms must be able to survive a range of conditions, called the "range of tolerance". Outside that are the "zones of physiological stress", where the survival and reproduction are possible but not optimal. Beyond these zones are the "zones of intolerance", where survival and reproduction of that organism

5046-439: The criteria for determining death for adults versus infants, and whole-brain versus higher-brain versus brainstem death. Non-heart-beating organ donation or NHBD is the procurement of organs after cardiac death. Cardiac death is determined after a patient has suffered cardiac arrest for two to five minutes. Deciding on which criteria to follow for determining brain death is still heavily debated today. Whole-brain criteria are

5133-422: The deep Mariana Trench , and inside rocks up to 580 m (1,900 ft; 0.36 mi) below the sea floor under 2,590 m (8,500 ft; 1.61 mi) of ocean off the coast of the northwestern United States, and 2,400 m (7,900 ft; 1.5 mi) beneath the seabed off Japan. In 2014, life forms were found living 800 m (2,600 ft; 0.50 mi) below the ice of Antarctica. Expeditions of

5220-399: The environment. Legal death Most legal determinations of death in the developed world are made by medical professionals who pronounce death when specific criteria are met. Two categories of legal death are death determined by irreversible cessation of heartbeat ( cardiopulmonary death ), and death determined by irreversible cessation of functions of the brain ( brain death ). In

5307-523: The exception being sulfur. The latter is a component of the amino acids cysteine and methionine . The most abundant of these elements in organisms is carbon, which has the desirable attribute of forming multiple, stable covalent bonds . This allows carbon-based (organic) molecules to form the immense variety of chemical arrangements described in organic chemistry . Alternative hypothetical types of biochemistry have been proposed that eliminate one or more of these elements, swap out an element for one not on

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5394-409: The formation of colonies of identical cells. These cells can form group organisms through cell adhesion . The individual members of a colony are capable of surviving on their own, whereas the members of a true multi-cellular organism have developed specialisations, making them dependent on the remainder of the organism for survival. Such organisms are formed clonally or from a single germ cell that

5481-474: The formation of Earth's major animal and plant species. This interplay between organisms and their environment is an inherent feature of living systems. The biosphere is the global sum of all ecosystems. It can also be termed as the zone of life on Earth, a closed system (apart from solar and cosmic radiation and heat from the interior of the Earth), and largely self-regulating. Organisms exist in every part of

5568-406: The fungi are more closely related to animals than to plants. As advances in microscopy enabled detailed study of cells and microorganisms, new groups of life were revealed, and the fields of cell biology and microbiology were created. These new organisms were originally described separately in protozoa as animals and protophyta/thallophyta as plants, but were united by Ernst Haeckel in

5655-480: The future to the past) is in contradiction with the scientific evidence for natural selection, which explains the consequence in terms of a prior cause. Biological features are explained not by looking at future optimal results, but by looking at the past evolutionary history of a species, which led to the natural selection of the features in question. Spontaneous generation was the belief that living organisms can form without descent from similar organisms. Typically,

5742-426: The given environment. This implies all or most of the following traits: From a physics perspective, an organism is a thermodynamic system with an organised molecular structure that can reproduce itself and evolve as survival dictates. Thermodynamically, life has been described as an open system which makes use of gradients in its surroundings to create imperfect copies of itself. Another way of putting this

5829-484: The heart, brain death is a determination that the brain biologically cannot be resuscitated. If a clinically dead person has suffered injuries so severe that resuscitation is obviously impossible, then in some jurisdictions first responders may make a legal determination of cardiopulmonary death. Such a person is said to be dead on arrival (DOA) or dead at the scene . In some cases, a person will be declared dead even without any remains or doctor's declaration. This

5916-434: The idea was that certain forms such as fleas could arise from inanimate matter such as dust or the supposed seasonal generation of mice and insects from mud or garbage. The theory of spontaneous generation was proposed by Aristotle , who compiled and expanded the work of prior natural philosophers and the various ancient explanations of the appearance of organisms; it was considered the best explanation for two millennia. It

6003-496: The information to be preserved during reproduction and cell division. Within cells, DNA is organised into long structures called chromosomes . During cell division these chromosomes are duplicated in the process of DNA replication , providing each cell its own complete set of chromosomes. Eukaryotes store most of their DNA inside the cell nucleus . Cells are the basic unit of structure in every living thing, and all cells arise from pre-existing cells by division . Cell theory

6090-642: The kingdom Protista ; later, the prokaryotes were split off in the kingdom Monera , which would eventually be divided into two separate groups, the Bacteria and the Archaea . This led to the six-kingdom system and eventually to the current three-domain system , which is based on evolutionary relationships. However, the classification of eukaryotes, especially of protists, is still controversial. As microbiology developed, viruses, which are non-cellular, were discovered. Whether these are considered alive has been

6177-563: The list, or change required chiralities or other chemical properties. Deoxyribonucleic acid or DNA is a molecule that carries most of the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses. DNA and RNA are nucleic acids ; alongside proteins and complex carbohydrates , they are one of the three major types of macromolecule that are essential for all known forms of life. Most DNA molecules consist of two biopolymer strands coiled around each other to form

6264-437: The local court declined and ruled he was still legally dead because Ohio state law does not allow reversing legal declarations of death if more than three years have passed. In 2016, Frenchwoman Jeanne Pouchain was erroneously declared dead by a French court of appeal hearing an employment dispute. The error was upheld in court in 2017. As of 2021 , Pouchain was still fighting to be legally recognized as alive. In some cases,

6351-508: The middle of the 19th century. It appealed to philosophers such as Henri Bergson , Friedrich Nietzsche , and Wilhelm Dilthey , anatomists like Xavier Bichat , and chemists like Justus von Liebig . Vitalism included the idea that there was a fundamental difference between organic and inorganic material, and the belief that organic material can only be derived from living things. This was disproved in 1828, when Friedrich Wöhler prepared urea from inorganic materials. This Wöhler synthesis

6438-448: The non-living. Legal definitions of life have been debated, though these generally focus on the decision to declare a human dead, and the legal ramifications of this decision. At least 123 definitions of life have been compiled. Since there is no consensus for a definition of life, most current definitions in biology are descriptive. Life is considered a characteristic of something that preserves, furthers or reinforces its existence in

6525-566: The oldest from the Archaean Eon, up to 3.4 billion years old. Extinction is the process by which a species dies out. The moment of extinction is the death of the last individual of that species. Because a species' potential range may be very large, determining this moment is difficult, and is usually done retrospectively after a period of apparent absence. Species become extinct when they are no longer able to survive in changing habitat or against superior competition. Over 99% of all

6612-609: The parent cell divides into two or more daughter cells. For prokaryotes, cell division occurs through a process of fission in which the DNA is replicated, then the two copies are attached to parts of the cell membrane. In eukaryotes , a more complex process of mitosis is followed. However, the result is the same; the resulting cell copies are identical to each other and to the original cell (except for mutations ), and both are capable of further division following an interphase period. Multicellular organisms may have first evolved through

6699-473: The preserved remains or traces of organisms from the remote past. The totality of fossils, both discovered and undiscovered, and their placement in layers ( strata ) of sedimentary rock is known as the fossil record . A preserved specimen is called a fossil if it is older than the arbitrary date of 10,000 years ago. Hence, fossils range in age from the youngest at the start of the Holocene Epoch to

6786-445: The property is distributed. In most cases, it would go to next of kin , such as a spouse or adult child. If the person who died is wealthy, often a portion of their property will be collected by an estate tax . There are a few controversies surrounding the topic of legal death among health professionals and the general public. The main issues argued amongst bioethicists include but are not limited to; non-heart-beating organ donation,

6873-460: The ribosomes through an enzyme-catalyzed process called protein biosynthesis . A sequence of amino acids is assembled and joined based upon gene expression of the cell's nucleic acid. In eukaryotic cells, these proteins may then be transported and processed through the Golgi apparatus in preparation for dispatch to their destination. Cells reproduce through a process of cell division in which

6960-435: The soul, like everything else, was composed of fiery atoms. He elaborated on fire because of the apparent connection between life and heat, and because fire moves. Plato , in contrast, held that the world was organised by permanent forms , reflected imperfectly in matter; forms provided direction or intelligence, explaining the regularities observed in the world. The mechanistic materialism that originated in ancient Greece

7047-493: The species that have ever lived are now extinct. Mass extinctions may have accelerated evolution by providing opportunities for new groups of organisms to diversify. The diversity of life on Earth is a result of the dynamic interplay between genetic opportunity , metabolic capability, environmental challenges, and symbiosis . For most of its existence, Earth's habitable environment has been dominated by microorganisms and subjected to their metabolism and evolution. As

7134-488: The star within a galaxy may also affect the likelihood of life forming. Stars in regions with a greater abundance of heavier elements that can form planets, in combination with a low rate of potentially habitat -damaging supernova events, are predicted to have a higher probability of hosting planets with complex life. The variables of the Drake equation are used to discuss the conditions in planetary systems where civilisation

7221-408: The sugar of one nucleotide and the phosphate of the next, resulting in an alternating sugar-phosphate backbone . According to base pairing rules (A with T, and C with G), hydrogen bonds bind the nitrogenous bases of the two separate polynucleotide strands to make double-stranded DNA. This has the key property that each strand contains all the information needed to recreate the other strand, enabling

7308-413: The universe is made up of a combination of four eternal "elements" or "roots of all": earth, water, air, and fire. All change is explained by the arrangement and rearrangement of these four elements. The various forms of life are caused by an appropriate mixture of elements. Democritus (460 BC) was an atomist ; he thought that the essential characteristic of life was having a soul ( psyche ), and that

7395-414: Was decisively dispelled by the experiments of Louis Pasteur in 1859, who expanded upon the investigations of predecessors such as Francesco Redi . Disproof of the traditional ideas of spontaneous generation is no longer controversial among biologists. Vitalism is the belief that there is a non-material life-principle. This originated with Georg Ernst Stahl (17th century), and remained popular until

7482-495: Was formulated by Henri Dutrochet , Theodor Schwann , Rudolf Virchow and others during the early nineteenth century, and subsequently became widely accepted. The activity of an organism depends on the total activity of its cells, with energy flow occurring within and between them. Cells contain hereditary information that is carried forward as a genetic code during cell division. There are two primary types of cells, reflecting their evolutionary origins. Prokaryote cells lack

7569-486: Was revived and revised by the French philosopher René Descartes (1596–1650), who held that animals and humans were assemblages of parts that together functioned as a machine. This idea was developed further by Julien Offray de La Mettrie (1709–1750) in his book L'Homme Machine . In the 19th century the advances in cell theory in biological science encouraged this view. The evolutionary theory of Charles Darwin (1859)

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