or
99-535: Patrick Galen Dempsey (born January 13, 1966) is an American actor and racing driver. He is best known for his role as neurosurgeon Dr. Derek "McDreamy" Shepherd in the ABC medical drama series Grey's Anatomy (2005-15; 2020-21). He is also known for his leading man romantic films roles, including in Enchanted (2007). Dempsey has received nominations for a Primetime Emmy Award and two Golden Globe Awards , and
198-429: A Chicago hospice on February 4, 2018, due to complications from throat cancer , originally diagnosed in 2014. He was 77 years old. According to his friend Anna D. Shapiro , "He was fragile and he was supposed to be having a routine procedure. But having just beat Stage 3 throat cancer, I think he was just too weak ... By the time he did The Rembrandt he was clean of cancer ... But other health issues came up and he
297-408: A fellowship after residency, or, in some cases, as a senior resident in the form of an enfolded fellowship. These fellowships include pediatric neurosurgery , trauma/neurocritical care, functional and stereotactic surgery, surgical neuro- oncology , radiosurgery , neurovascular surgery, skull-base surgery, peripheral nerve and complex spinal surgery. Fellowships typically span one to two years. In
396-527: A professional , scientific , non governmental organization , is composed of 130 member societies: consisting of 5 Continental Associations ( AANS , AASNS , CAANS , EANS and FLANC ), 6 Affiliate Societies, and 119 National Neurosurgical Societies, representing some 50,000 neurosurgeons worldwide. It has a consultative status in the United Nations . The official Journal of the Organization
495-514: A Bowdoin graduate after an alumnus led a petition signed by over 450 students to "adopt" the character as an alumnus. In 2023, Dempsey helped raise funds for families of the Lewiston shooting victims. He joined a charity softball tournament with former Boston Red Sox pitcher Bill "Spaceman" Lee . Dempsey was diagnosed with dyslexia at age 12. As a result, it is necessary for him to memorize all his lines to perform, even for auditions where he
594-598: A Lola B12/80 coupe in the Prototype 2 class from Laguna Seca onward. After debuting at the 2009 24 Hours of Le Mans , Dempsey returned to France four years later and competed in a Porsche 997 GT3 RSR at the 2013 24 Hours of Le Mans endurance race. Dempsey and his co-drivers finished 29th overall and fourth in-class. In 2015, Dempsey focused on participating in the FIA World Endurance Championship with his own Dempsey Racing-Proton team in
693-855: A brief conversation with Frasier. Mahoney also appeared as a priest in Becker , which starred Cheers star Ted Danson . Mahoney's first voice job was in W. B. Yeats 's "The Words upon the Window-Pane" for the award-winning National Radio Theater of Chicago . He provided the voices for several characters in Antz (1998), Preston Whitmore in Atlantis: The Lost Empire and Atlantis: Milo's Return , General Rogard in The Iron Giant (1999), and Papi in Kronk's New Groove (but
792-449: A daily basis." Dempsey, who maintains an extensive sports and vintage car collection, has enjoyed auto racing in his spare time for several years. Before the 24 Hours of Le Mans in 2013, he said that he would like to compete full-time, telling Eurosport: I would like to make that [motorsports] a complete priority and just focus on this full-time. If I could just walk away from acting, I think I could do that very easily, and just focus on
891-404: A disc is removed it is replaced by an implant which will create a bony fusion between vertebral bodies above and below. Instead, a mobile disc could be implanted into the disc space to maintain mobility. This is commonly used in cervical disc surgery. At times instead of disc removal a Laser discectomy could be used to decompress a nerve root. This method is mainly used for lumbar discs. Laminectomy
990-574: A guest driver, he was ineligible to score points. He has been the face of L'Oreal and Versace and was featured in ads for Serengeti sunglasses. In November 2008, he launched an Avon fragrance named Unscripted. In June 2009, Women's Wear Daily reported the launch of a second Avon fragrance named Patrick Dempsey 2. The fragrance was recognized as the "Men's Private Label/Direct Sell" for the 2010 FiFi Awards . On September 29, 2012, Mexican cable company Cablemás , Megacable and Mexico city's Cablevisión launched an advertising campaign featuring Dempsey as
1089-537: A legal dispute with investor group Global Baristas, Dempsey left the group, in effect officially leaving his managerial positions with Tully's. Dempsey filed a lawsuit on behalf of Global Baristas, claiming Michael Avenatti borrowed $ 2 million against Tully's assets without informing Dempsey, rather than fully financing the coffee chain as was promised, calling the 15 percent interest rate on the loan "exorbitant" and sued for Avenatti to fund Tully's operations and meet its working capital needs, as well as for any damages owed
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#17327916368521188-672: A member of the Steppenwolf Theatre Company . He earned the Tony Award for Best Featured Actor in a Play for his performance in the 1986 Broadway revival of John Guare 's The House of Blue Leaves , and went on to achieve wider recognition for his roles in the films Suspect and Moonstruck (both 1987). Other credits included Tin Men (1987), Frantic , Eight Men Out (both 1988), Say Anything... (1989), Barton Fink (1991), Striking Distance , In
1287-606: A millimeter of desired accuracy. Other tools, such as hand held power saws and robots have only recently been commonly used inside of a neurological operating room. As an example, the University of Utah developed a device for computer-aided design / computer-aided manufacturing (CAD-CAM) which uses an image-guided system to define a cutting tool path for a robotic cranial drill . The World Federation of Neurosurgical Societies ( WFNS ), founded in 1955, in Switzerland , as
1386-498: A minimum period of seven years after graduating from medical school. In the United Kingdom , students must gain entry into medical school. The MBBS qualification ( Bachelor of Medicine, Bachelor of Surgery ) takes four to six years depending on the student's route. The newly qualified physician must then complete foundation training lasting two years; this is a paid training program in a hospital or clinical setting covering
1485-439: A minute target in the brain through a minimal opening. This is used in functional neurosurgery where electrodes are implanted or gene therapy is instituted with high level of accuracy as in the case of Parkinson's disease or Alzheimer's disease. Using the combination method of open and stereotactic surgery, intraventricular hemorrhages can potentially be evacuated successfully. Conventional surgery using image guidance technologies
1584-508: A motion picture. In 2009, he raced a Team Seattle Advanced Engineering Ferrari F430 GT in the 2009 24 Hours of Le Mans 's GT2 class and finished ninth in class. Dempsey announced he would race the 2011 Rolex 24 at Daytona along with other races throughout the season in a Mazda RX-8. Dempsey finished in third place in the GT Class of the Rolex 24 at Daytona. In 2012, Dempsey competed in
1683-504: A national uproar. He then co-starred in the third installment of the comedy classic Meatballs III: Summer Job , alongside Sally Kellerman in 1987. This was followed by the teen comedy Can't Buy Me Love in 1987 with actress Amanda Peterson and Some Girls with Jennifer Connelly in 1988. In 1989, Dempsey had the lead role in the films Loverboy with actress Kirstie Alley and Happy Together with actress Helen Slater . Dempsey made several featured appearances in television in
1782-623: A new play by Bruce Graham at Northlight Theatre in Skokie, Illinois ( suburban Chicago ). The play also stars fellow Chicago actors Rondi Reed and Thom Cox . In 2011, he had two guest appearances on Hot in Cleveland as Roy, a waiter and a love interest for Betty White 's character Elka. This reunited him with his Frasier co-star Jane Leeves , as well as Wendie Malick whose character he eventually married in Frasier and his co-star in
1881-592: A patient while removing a small tumor, and awoke the patient by pouring onion and vinegar in the patient's mouth. The combination of carbon dioxide, hydrogen, and nitrogen, was a form of neuroanesthesia adopted in the 18th century and introduced by Humphry Davy . Various Imaging methods are used in modern neurosurgery diagnosis and treatment. They include computer assisted imaging computed tomography (CT) , magnetic resonance imaging (MRI), positron emission tomography (PET), magnetoencephalography (MEG), and stereotactic radiosurgery . Some neurosurgery procedures involve
1980-633: A person developing a chronic post- craniotomy headache. Approaches to treating pain in adults include treatment with nonsteroidal anti‐inflammatory drugs ( NSAIDs ), which have been shown to reduce pain for up to 24 hours following surgery. Low-quality evidence supports the use of the medications dexmedetomidine , pregabalin or gabapentin to reduce post-operative pain. Low-quality evidence also supports scalp blocks and scalp infiltration to reduce postoperative pain. Gabapentin or pregabalin may also decrease vomiting and nausea following surgery, based on very low-quality medical evidence. Neurosurgery
2079-607: A point where how much is enough, really? I'm focusing now on developing and racing and being a father to my children. In 2016, Dempsey starred in the Universal Pictures film Bridget Jones's Baby with Renée Zellweger and Colin Firth , and in 2018 he appeared on Epix television miniseries The Truth About the Harry Quebert Affair . In 2017 he participated in the short film Red Nose Day Actually ,
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#17327916368522178-399: A range of medical specialties including surgery. Junior doctors then apply to enter the neurosurgical pathway. Unlike most other surgical specialties, it currently has its own independent training pathway which takes around eight years (ST1-8); before being able to sit for consultant exams with sufficient amounts of experience and practice behind them. Neurosurgery remains consistently amongst
2277-454: A result of highly crafted tools. Modern neurosurgical tools, or instruments, include chisels , curettes, dissectors, distractors, elevators, forceps, hooks, impactors, probes, suction tubes, power tools, and robots. Most of these modern tools have been in medical practice for a relatively long time. The main difference of these tools in neurosurgery, were the precision in which they were crafted. These tools are crafted with edges that are within
2376-487: A role in the stage production of Torch Song Trilogy led to Patrick Dempsey's discovery as an actor. His audition was successful and he spent the following four months touring with the company in Philadelphia . He followed this with another tour, Brighton Beach Memoirs , in the lead role, which was directed by Gene Saks . Dempsey has also made notable appearances in the stage productions of On Golden Pond , with
2475-498: A sequel to the 2003 romantic comedy Love Actually . Dempsey played the role of the husband of Laura Linney 's character Sarah. Starting from 2020 he has portrayed Harry Morgan in the Sky Atlantic financial thriller series Devils . On February 4, 2020, Dempsey signed on to star as the lead of a CBS political drama pilot Ways & Means , where he would portray a Congressional leader. Initially planned to be considered for
2574-611: A team. Repair of craniofacial disorders and disturbance of cerebrospinal fluid circulation is done by neurosurgeons who also occasionally team up with maxillofacial and plastic surgeons. Cranioplasty for craniosynostosis is performed by pediatric neurosurgeons with or without plastic surgeons. Neurosurgeons are involved in stereotactic radiosurgery along with radiation oncologists in tumor and AVM treatment. Radiosurgical methods such as Gamma knife , Cyberknife and Novalis Radiosurgery are used as well. Endovascular neurosurgery utilize endovascular image guided procedures for
2673-794: Is World Neurosurgery . The other global organisations being the World Academy of Neurological Surgery (WANS) and the World Federation of Skull Base Societies (WFSBS). General neurosurgery involves most neurosurgical conditions including neuro-trauma and other neuro-emergencies such as intracranial hemorrhage . Most level 1 hospitals have this kind of practice. Specialized branches have developed to cater to special and difficult conditions. These specialized branches co-exist with general neurosurgery in more sophisticated hospitals. To practice advanced specialization within neurosurgery, additional higher fellowship training of one to two years
2772-399: Is a field of anesthesiology which focuses on neurosurgery. Anesthesia is not used during the middle of an "awake" brain surgery. Awake brain surgery is where the patient is conscious for the middle of the procedure and sedated for the beginning and end. This procedure is used when the tumor does not have clear boundaries and the surgeon wants to know if they are invading on critical regions of
2871-418: Is a part of practical medicine and the only specialty that involves invasive intervention in the activity of the living brain. The brain ensures the structural and functional integrity of the body and the implementation of all the main life processes of the body. Therefore, neurosurgery faces a wide range of bioethical issues and a significant selection of the latest treatment technologies. Neurosurgery has
2970-411: Is also becoming common and is referred to as surgical navigation, computer-assisted surgery, navigated surgery, stereotactic navigation. Similar to a car or mobile Global Positioning System (GPS), image-guided surgery systems, like Curve Image Guided Surgery and StealthStation, use cameras or electromagnetic fields to capture and relay the patient's anatomy and the surgeon's precise movements in relation to
3069-444: Is commonly utilized by neurosurgeons when appropriate. Techniques such as endoscopic endonasal surgery are used in pituitary tumors, craniopharyngiomas , chordomas, and the repair of cerebrospinal fluid leaks. Ventricular endoscopy is used in the treatment of intraventricular bleeds, hydrocephalus, colloid cyst and neurocysticercosis . Endonasal endoscopy is at times carried out with neurosurgeons and ENT surgeons working together as
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3168-516: Is expected from the neurosurgeon. Some of these divisions of neurosurgery are: According to an analysis by the American College of Surgeons National Surgical Quality Improvement Program (NSQIP), the most common surgeries performed by neurosurgeons in between 2006 and 2014 were the following: Neuropathology is a specialty within the study of pathology focused on the disease of the brain, spinal cord, and neural tissue. This includes
3267-405: Is normal pressure hydrocephalus (NPH). Neurosurgery of the spine covers the cervical, thoracic and lumbar spine. Some indications for spine surgery include spinal cord compression resulting from trauma, arthritis of the spinal discs, or spondylosis. In cervical cord compression, patients may have difficulty with gait, balance issues, and/or numbness and tingling in the hands or feet. Spondylosis
3366-577: Is the medical specialty that focuses on the surgical treatment or rehabilitation of disorders which affect any portion of the nervous system including the brain , spinal cord , peripheral nervous system , and cerebrovascular system. Neurosurgery as a medical specialty also includes non-surgical management of some neurological conditions. In different countries, there are different requirements for an individual to legally practice neurosurgery, and there are varying methods through which they must be educated. In most countries, neurosurgeon training requires
3465-414: Is the condition of spinal disc degeneration and arthritis that may compress the spinal canal. This condition can often result in bone-spurring and disc herniation . Power drills and special instruments are often used to correct any compression problems of the spinal canal. Disc herniations of spinal vertebral discs are removed with special rongeurs . This procedure is known as a discectomy . Generally once
3564-567: Is the removal of the lamina of the vertebrae of the spine in order to make room for the compressed nerve tissue. Surgery for chronic pain is a sub-branch of functional neurosurgery. Some of the techniques include implantation of deep brain stimulators, spinal cord stimulators, peripheral stimulators and pain pumps. Surgery of the peripheral nervous system is also possible, and includes the very common procedures of carpal tunnel decompression and peripheral nerve transposition. Numerous other types of nerve entrapment conditions and other problems with
3663-433: Is unlikely to get the part. Entertainment Weekly put Dempsey's hair on its end-of-the-decade "best-of" list, saying, "What made Grey's Anatomy a mega-medi-hit? It could have something to do with creator Shonda Rhimes's scalpel-sharp writing… or McDreamy's impossibly luxurious man hair. Just saying." In 2005, People magazine ranked him second in its annual list of "Sexiest Men Alive" and again in 2006. Patrick Dempsey
3762-653: The 2013 24 Hours of Le Mans , Dempsey declared that he would "walk away" from acting if he could and dedicate himself full-time to motorsports . Dempsey was born in Lewiston, Maine , and grew up in the nearby towns of Turner and Buckfield . He has two older sisters. His mother, Amanda ( née Casson), was a school secretary, and his father, William, was an insurance salesman. He attended Leavitt Area High School, Buckfield High School and St. Dominic Regional High School , and after moving to Houston attended Willowridge High School . In his youth, Dempsey participated in juggling competitions. In 1981, he achieved second place at
3861-603: The 2020-21 televisions season , the pilot was rolled into consideration for the following season due to the COVID-19 pandemic. CBS ultimately passed on the finished pilot in May 2021. In January 2021, it was announced that Dempsey would reprise his role in the Enchanted sequel, Disenchanted , which began production in spring of that year. The film was released on Disney+ in late 2022. In 2023, he portrayed Sheriff Eric Newlon in
3960-595: The International Jugglers' Association Championship in the Juniors category, just behind Anthony Gatto , who is considered to be the best technical juggler of all time. Dempsey was diagnosed with dyslexia at age 12. He told Barbara Walters on her 2008 Oscar special that he thinks dyslexia made him what he is today. "It's given me a perspective of — you have to keep working," Dempsey told Walters. "I have never given up." An invitation to audition for
4059-700: The Middle Ages in Al-Andalus from 936 to 1013 AD, Al-Zahrawi performed surgical treatments of head injuries, skull fractures, spinal injuries, hydrocephalus , subdural effusions and headache. During the Roman Empire , doctors and surgeons performed neurosurgery on depressed skull fractures. Simple forms of neurosurgery were performed on King Henri II in 1559, after a jousting accident with Gabriel Montgomery fatally wounded him. Ambroise Paré and Andreas Vesalius , both experts in their field at
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4158-604: The Steppenwolf Theatre . He did so and went on to win the Clarence Derwent Award as Most Promising Male Newcomer in 1986. Steppenwolf founder Gary Sinise said in an interview for Bomb Magazine that Lyle Kessler 's play Orphans in 1985 "kicked John Mahoney, Kevin Anderson and Terry Kinney off into the movie business" after their Steppenwolf performance of the play for which he won
4257-799: The United States Army . After graduating from Quincy, he lived in Macomb, Illinois , and earned his Master's degree in English from Western Illinois University , where he went on to teach English in the late 1960s before settling in Forest Park, Illinois , and later in Oak Park, Illinois . He became a U.S. citizen in 1971 and served as an associate editor of the Quality Review Bulletin medical journal through much of
4356-695: The Wolfgang Petersen directed drama In the Line of Fire (1993), Grant Gubler in Ben Stiller 's romance film Reality Bites (1994), environmental lobbyist Leo Solomon in Rob Reiner 's political romance film The American President (1995) and John Shaughnessy in the legal mystery thriller Primal Fear (1996). He also is known for his collaboration with the Coen brothers in films such as
4455-618: The cochlear implant , a neurological prosthetic that allowed deaf people to hear was marketed for commercial use. In 1998 researcher Philip Kennedy implanted the first Brain Computer Interface (BCI) into a human subject. A survey done in 2010 on 100 most cited works in neurosurgery shows that the works mainly cover clinical trials evaluating surgical and medical therapies, descriptions of novel techniques in neurosurgery, and descriptions of systems classifying and grading diseases. The main advancements in neurosurgery came about as
4554-580: The schizophrenic brother of Lily ( Sela Ward ). Dempsey received an Emmy nomination in 2001 as Outstanding Guest Actor in a Drama Series for the role of Aaron. In 1993, he played a young John F. Kennedy in the two-part TV mini-series JFK: Reckless Youth . In 2000, he played Detective Kincaid in Scream 3 . Dempsey had a high-profile role as the fiancé of Reese Witherspoon 's character in Sweet Home Alabama (2002). In 2004, he co-starred in
4653-573: The 1990s; he was cast several times in pilots that were not picked up for a full season, including lead roles in the TV versions of the films The Player and About A Boy . He received positive reviews, however, as he portrayed real-life mob boss , Meyer Lansky in 1991 when Mobsters was put on the screen. His first major television role was a three-episode stint as Will Truman 's closeted sportscaster boyfriend on Will & Grace . He appeared in four episodes of Once & Again as Aaron Brooks,
4752-473: The 2006 Golden Globe Awards for the role. His success on the show has led to his becoming a spokesman for Mazda and State Farm Insurance. BuddyTV ranked him #1 on its list of "TV's Sexiest Men of 2011". In November 2020, Dempsey appeared as Derek Shepherd at the start of the series' 17th season for the first time since the character had died in April 2015. Following his departure from Grey's Anatomy , Dempsey
4851-720: The Broadway revival of Prelude to a Kiss at the American Airlines Theater in a limited-run engagement running from previews on February 17, 2007, through to April 29, 2007. He appeared as an elderly drag queen in the ER season 13 episode "Somebody to Love," and co-starred with Steve Carell (himself a veteran of Chicago theater ) as the father of Carell's character in Dan in Real Life . In March 2008, he opened in
4950-714: The Derwent Award and the Theatre World Award. Mahoney won Broadway 's Tony Award for Best Featured Actor in a Play in 1986 for his performance in John Guare 's The House of Blue Leaves . Mahoney's first major film roles both came in 1987, in Barry Levinson 's Tin Men and in Peter Yates ' Suspect , a courtroom drama/mystery starring Cher , Dennis Quaid , and Liam Neeson . In
5049-487: The GTE-Am class in a Porsche 997 GT3 RSR , teamed with Patrick Long and Marco Seefried. He told Porsche Newsroom: "Not much changes in my TV work, but everything changes constantly in motor racing – every lap, every bend and every moment." Not eligible for points. ( key ) (Results are overall / class ) Did not complete sufficient laps in order to score points. ( key ) (Results are overall / class ) ‡ As Dempsey
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#17327916368525148-894: The Grand-Am Continental Tire Sports Car Challenge behind the wheel of an Aston Martin Racing - Multimatic Motorsports Aston Martin Vantage GT4 , which, after five successful racing seasons in Europe, was to make its debut on American tracks. He formed the Dempsey Racing team to compete in the American Le Mans Series . The team fielded a full-time Oreca FLM09 in the Prototype Challenge class as well as
5247-642: The Lewiston–Auburn area. On May 28, 2017, Dempsey received an honorary doctorate from Bates College in his hometown, Lewiston, Maine, for his philanthropy in the town and funding of "the Dempsey Center — just blocks from the Bates campus." Dempsey was awarded an honorary doctorate by Bowdoin College in 2013 for his philanthropic work. His Grey's Anatomy character Derek Shepherd had been written as
5346-470: The Line of Fire (both 1993), Reality Bites (1994), The American President (1995), Primal Fear (1996), and The Broken Hearts Club (2000). He also voiced roles in animated films such as Antz (1998), The Iron Giant (1999), and Atlantis: The Lost Empire (2001). Charles John Mahoney was born in Blackpool , England , on June 20, 1940, the seventh of eight children. His father, Reg,
5445-694: The Maine Acting Company, and as Timmy (the Martin Sheen role) in a 1990 off- Broadway revival of The Subject Was Roses co-starring with John Mahoney and Dana Ivey at the Roundabout Theatre in New York. Dempsey's first major feature film role was at age 21 with Beverly D'Angelo in the film In The Mood , the actual World War II story about Ellsworth Wisecarver whose relationships with older married women created
5544-607: The Moon (2011), Thanksgiving (2023), and Ferrari (2023). He starred in and produced Flypaper (2011), and The Art of Racing in the Rain (2019). Dempsey, who maintains a sports car and vintage car collection, enjoys auto racing in his spare time. He has competed in events such as the 24 Hours of Le Mans and Rolex 24 at Daytona sports car races , and the Ensenada SCORE Baja 1000 off-road race . Prior to
5643-579: The Patrick Dempsey Center at Central Maine Medical Center in Lewiston. In October 2009, when Dempsey introduced the first Dempsey Challenge, registration was closed after reaching the goal of 3,500 cyclists, runners and walkers. The event raised more than $ 1 million for the cancer center. His mother was in the crowd as Dempsey finished his 50-mile (80 km) ride. The Challenge has since become an annual October event presented by Amgen in
5742-441: The U.S., neurosurgery is a very small, highly competitive specialty, constituting only 0.5 percent of all physicians. Neurosurgery, or the premeditated incision into the head for pain relief, has been around for thousands of years, but notable advancements in neurosurgery have only come within the last hundred years. The Incas appear to have practiced a procedure known as trepanation since before European colonization. During
5841-416: The balance between benefits and risks. It is mostly rejected as a treatment now and non-compliant with patients' rights . History of electrodes in the brain : In 1878, Richard Caton discovered that electrical signals transmitted through an animal's brain. In 1950 Jose Delgado invented the first electrode that was implanted in an animal's brain (bull), using it to make it run and change direction. In 1972
5940-429: The brain or spinal cord. While pathology has been studied for millennia only within the last few hundred years has medicine focused on a tissue- and organ-based approach to tissue disease. In 1810, Thomas Hodgkin started to look at the damaged tissue for the cause. This was conjoined with the emergence of microscopy and started the current understanding of how the tissue of the human body is studied. Neuroanesthesia
6039-623: The brain which involve functions like talking, cognition , vision, and hearing. It will also be conducted for procedures which the surgeon is trying to combat epileptic seizures. The physician Hippocrates (460–370 BCE) made accounts of using different wines to sedate patients while trepanning. In 60 CE, Dioscorides , a physician, pharmacologist, and botanist, detailed how mandrake , henbane , opium , and alcohol were used to put patients to sleep during trepanning. In 972 CE, two brother surgeons in Paramara , now India, used "samohine" to sedate
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#17327916368526138-461: The brain's prefrontal cortex . The originator of the procedure, Portuguese neurologist António Egas Moniz , shared the Nobel Prize for Physiology or Medicine of 1949. Some patients improved in some ways after the operation, but complications and impairments – sometimes severe – were frequent. The procedure was controversial from its initial use, in part due to
6237-402: The cast of In Treatment for the series' second season (2009) as a frenetic CEO who is overwhelmed by his personal and professional responsibilities and experiences chronic physical anxiety attacks. In 2010, he made a guest appearance on $ #*! My Dad Says as homophobic retired naval officer Lt. Commander Wally Durham. Beginning in April 2011, Mahoney began rehearsing The Outgoing Tide ,
6336-491: The central nervous system and the peripheral nervous system. Tissue analysis comes from either surgical biopsies or post mortem autopsies . Common tissue samples include muscle fibers and nervous tissue. Common applications of neuropathology include studying samples of tissue in patients who have Parkinson's disease , Alzheimer's disease , dementia , Huntington's disease , amyotrophic lateral sclerosis , mitochondria disease , and any disorder that has neural deterioration in
6435-514: The character Kenai in Brother Bear sequel Brother Bear 2 , replacing Joaquin Phoenix . Dempsey's most recent roles include the 2008 film Made of Honor as Tom, and the 2010 romantic comedy Valentine's Day ; the latter film follows five interconnecting stories about Los Angelinos anticipating (or in some cases dreading) the holiday of love. Universal Pictures acquired the rights to
6534-529: The company. Soon after, Dempsey's lawyer's office issued a statement saying the partnership was dissolved and that Dempsey wished the lawyer and the company "all the best". Avenatti has stated the dispute was a "misunderstanding" and will continue operating with other investors and new management. In 1997, Dempsey's mother, Amanda, was diagnosed with cancer which subsequently relapsed five times. On March 24, 2014, she died in Lewiston, Maine , aged 79. In response to his mother's bouts with cancer, Dempsey helped start
6633-513: The couple reconciled later in the year. They called off their divorce on November 12, 2016. Dempsey formerly owned a home in Harpswell, Maine near his hometown. His mother moved into a farm next to his home. Dempsey is a supporter of Scottish football club Rangers F.C. because of his Scottish connection through his step-grandfather. Neurosurgeon or Neurosurgery or neurological surgery , known in common parlance as brain surgery ,
6732-805: The driving, I would love that more than anything else. He has competed in prestigious events such as the 24 Hours of Le Mans and Rolex 24 at Daytona sports car races , and the Tecate SCORE Baja 1000 off-road race . He was a co-owner of the Vision Racing IndyCar Series team and current owner of Dempsey Racing, which is presently racing two Porsche 911 GT America's in the Tudor United Sports Car Series. He participated in this series as often as his schedule allowed, although insurance restrictions kept him from driving competitively while also filming
6831-479: The first primary brain tumor removal, which differs from Macewen's operation in that Bennett operated on the exposed brain, whereas Macewen operated outside of the "brain proper" via trepanation . On March 16, 1907, Austrian surgeon Hermann Schloffer became the first to successfully remove a pituitary tumor. Lobotomy : also known as leucotomy , was a form of psychosurgery , a neurosurgical treatment of mental disorders that involves severing connections in
6930-662: The following applied scientific and ethical problems: John Mahoney Charles John Mahoney (June 20, 1940 – February 4, 2018) was an English-American actor. He played retired police officer Martin Crane on the NBC sitcom Frasier from 1993 to 2004, receiving nominations for two Golden Globe Awards and two Primetime Emmy Awards . After moving from England to the United States, Mahoney began his career in Chicago as
7029-412: The gifts and talents that you've given me. Please help me to use all these gifts and talents to their fullest. And please accept this performance as a prayer of praise and thanks to you". Mahoney would also say prayers upon waking up and before going to sleep daily, and would repeatedly pray "Dear God, please help me to treat everybody – including myself – with love, respect, and dignity." Mahoney died in
7128-487: The highly acclaimed HBO production Iron Jawed Angels , opposite Hilary Swank and Anjelica Huston . He also appeared as special guest star in The Practice for its three-episode finale season (8x13-8x15). Dempsey has received significant public attention for his role as Dr. Derek "McDreamy" Shepherd in the medical drama Grey's Anatomy opposite Ellen Pompeo . Before landing the role, Dempsey auditioned for
7227-523: The late 1970s. Mahoney made a concerted effort to lose his English accent after joining the U.S. Army, not wanting to "stand out" in his new adopted country. He spoke with an American accent for the rest of his life. Dissatisfied with his career, Mahoney took acting classes at St. Nicholas Theatre, which inspired him to resign from his day job and pursue acting full-time. After a stage production in Chicago in 1977, John Malkovich encouraged him to join
7326-482: The love interest of a domestic worker who comes across his profile on an online dating site. Starting in 2013, Patrick Dempsey became the face of Silhouette, promoting eyewear fashion from Austria. From January 2017 Dempsey appears for Vodafone Italy and he appears in some Italian spots about it. In 2018, Bleusalt, a Malibu-based fashion brand launched a clothing line designed by the actor. In January 2013, Dempsey announced that his company (Global Baristas) had secured
7425-466: The most competitive medical specialties in which to obtain entry. In the United States , a neurosurgeon must generally complete four years of undergraduate education , four years of medical school , and seven years of residency (PGY-1-7). Most, but not all, residency programs have some component of basic science or clinical research. Neurosurgeons may pursue additional training in the form of
7524-585: The movie The American President . Mahoney was a featured ensemble cast member in The Birthday Party , playing in Chicago's Steppenwolf Theatre from January 24 to April 28, 2013. His last role was in the play The Rembrandt , which ran from September to November 2017. Despite the numerous successes throughout his career, Mahoney maintained that his early work in the play Orphans has "affected people more than any other play I've ever done. I still get mail from it, I still get people stopping me on
7623-573: The next decade, he had prominent roles in many acclaimed films including the John Patrick Shanley romantic comedy film Moonstruck (1987) starring Nicolas Cage and Cher. In 1988, Mahoney portrayed Kid Gleason in the sports drama Eight Men Out , and the following year portrayed the protective father in the Cameron Crowe teen coming of age film Say Anything... (1989). He portrayed Secret Service Director Sam Campagna in
7722-599: The open methods are still traditionally used in trauma or emergency situations. Microsurgery is utilized in many aspects of neurological surgery. Microvascular techniques are used in EC-IC bypass surgery and in restoration carotid endarterectomy . The clipping of an aneurysm is performed under microscopic vision. Minimally-invasive spine surgery utilizes microscopes or endoscopes. Procedures such as microdiscectomy, laminectomy , and artificial disc replacement rely on microsurgery. Using stereotaxy neurosurgeons can approach
7821-407: The patient, to computer monitors in the operating room. These sophisticated computerized systems are used before and during surgery to help orient the surgeon with three-dimensional images of the patient's anatomy including the tumor. Real-time functional brain mapping has been employed to identify specific functional regions using electrocorticography (ECoG) Minimally invasive endoscopic surgery
7920-515: The period black comedy Barton Fink and the screwball comedy The Hudsucker Proxy . Mahoney also played a pivotal gay role in Greg Berlanti's 2000 GLAAD Media Award -winning film The Broken Hearts Club: A Romantic Comedy . Mahoney appeared in Frasier from its debut in 1993 until the final episode in 2004. He received two Emmy nominations and two Golden Globe nominations for
8019-409: The peripheral nervous system are treated as well. Conditions treated by neurosurgeons include, but are not limited to: Pain following brain surgery can be significant and may lengthen recovery, increase the amount of time a person stays in the hospital following surgery, and increase the risk of complications following surgery. Severe acute pain following brain surgery may also increase the risk of
8118-575: The prize-winning novel The Art of Racing in the Rain in July 2009, for Dempsey to star in. The film instead starred Milo Ventimiglia. He starred as Dylan Gould in Transformers: Dark of the Moon (2011). In January 2014, he signed a two-year contract to remain on Grey's Anatomy , then in its tenth season, that would ensure his participation for potential 11th and 12th seasons. Dempsey was nominated for Best Actor – Television Series Drama at
8217-648: The role of Dr. Chase on another medical show, House . He also appeared in two episodes of the later Grey ' s spinoff Private Practice , playing the same character of Dr. Shepherd. The relationship his character had with Meredith Grey ( Ellen Pompeo ) on screen has received a lot of praise and positive reactions. In 2007, Dempsey starred in the Disney film Enchanted , and the Paramount Pictures film Freedom Writers , where he reunited with his Iron Jawed Angels co-star Hilary Swank . He also voiced
8316-455: The role of Martin Crane , the father of Frasier Crane and Niles Crane . NBC executives held Mahoney in such high esteem that Warren Littlefield declared he was pre-approved when the Frasier creative team suggested casting him as the father. Before appearing on the series, Mahoney had appeared in the episode " Do Not Forsake Me, O' My Postman " of Cheers – from which Frasier was a spinoff – as Sy Flembeck, an inept jingle writer who has
8415-589: The slasher film Thanksgiving and Piero Taruffi in the biographical sports drama Ferrari directed by Michael Mann . In 2014, Dempsey told Reuters in the Hockenheimring support paddock at the German Grand Prix that motor racing was not just a hobby, and had become as much a part of who he is as acting. He said, "It's all-consuming in many ways. I couldn't imagine not racing right now. It really keeps me motivated. It's all I think about on
8514-581: The street, and it's 20 years later." Mahoney lived in Oak Park, Illinois , and suffered from colon cancer in the mid-1980s. He was successfully treated for cancer again in 2014, and credited his love of acting and desire to continue it for giving him enough determination to survive both bouts, saying in October 2017: "I refused to yield to it because I love what I'm doing so much." Mahoney rarely spoke publicly about his private life, and he died without marrying or having any children. In 2002, he said, "I
8613-647: The suburb of Withington and discovered acting at the Stretford Children's Theatre . His parents' marriage was not happy. They would not speak to each other for long periods of time—and when they did, it often led to heated arguments. The family situation, combined with the war, fueled Mahoney's interest in acting and he vowed to leave Manchester. Mahoney moved to the United States aged 18 in 1959 when his older sister Vera (a war bride living in rural Illinois , where he had visited in 1951) agreed to sponsor him. He studied at Quincy University before joining
8712-564: The time, attempted their own methods, to no avail, in curing Henri. In China, Hua Tuo created the first general anaesthesia called mafeisan, which he used on surgical procedures on the brain. History of tumor removal : In 1879, after locating it via neurological signs alone, Scottish surgeon William Macewen (1848–1924) performed the first successful brain tumor removal. On November 25, 1884, after English physician Alexander Hughes Bennett (1848–1901) used Macewen's technique to locate it, English surgeon Rickman Godlee (1849–1925) performed
8811-488: The treatment of aneurysms , AVMs, carotid stenosis , strokes, and spinal malformations, and vasospasms. Techniques such as angioplasty , stenting, clot retrieval, embolization, and diagnostic angiography are endovascular procedures. A common procedure performed in neurosurgery is the placement of ventriculo-peritoneal shunt (VP shunt). In pediatric practice this is often implemented in cases of congenital hydrocephalus . The most common indication for this procedure in adults
8910-425: The use of intra-operative MRI and functional MRI. In conventional neurosurgery the neurosurgeon opens the skull, creating a large opening to access the brain. Techniques involving smaller openings with the aid of microscopes and endoscopes are now being used as well. Methods that utilize small craniotomies in conjunction with high-clarity microscopic visualization of neural tissue offer excellent results. However,
9009-529: The winning bid to purchase Seattle-based Tully's Coffee , which had filed for Chapter 11 bankruptcy protection in October. Dempsey's bid of $ 9.15M was enough to secure Tully's over the bids of six others, including Starbucks. Dempsey's company will control 47 Tully's locations in the Seattle area, but not the online business, which had been purchased by Green Mountain Coffee Roasters in 2009. Following
9108-515: The world premiere of Better Late at the Northlight Theatre . He was also the narrator for Midwest Airlines commercials. Mahoney also made two appearances on USA Network 's Burn Notice in the second (2009) and third (2010) season finales. His character, referred to only as "Management," is a senior intelligence agency official who is the apparent main mover of the conspiracy which blacklisted Michael Westen . Mahoney joined
9207-411: Was a baker who played classical piano, and his mother, Margaret (née Watson), was a housewife who loved reading. His paternal grandfather was Irish. The family had been evacuated to Blackpool from their home city of Manchester when it was heavily bombed during World War II . Mahoney started school at St Joseph's College . After the war, the family moved back to Manchester, where Mahoney grew up in
9306-400: Was a guest driver, he was ineligible to score points. ( key ) ‡ As Dempsey was a guest driver, he was ineligible to score points. ( key ) (Results are overall / class ) Did not complete sufficient laps in order to score points. ( key ) (Results are overall / class ) Did not complete sufficient laps in order to score points. * Season still in progress. ( key ) As Dempsey was
9405-735: Was named People magazine's 2023 "Sexiest Man Alive" for its November 2023 issue. Dempsey has been married twice. On August 24, 1987, he married his manager, actress and acting coach, Rochelle "Rocky" Parker, when he was 21 and she was 48. She appeared with Dempsey in the film In the Mood . While it has been reported that Dempsey married his best friend's mother, he has said that he became best friends with Parker's son only after he became romantically involved with Parker. The couple divorced on April 26, 1994. She died in 2014. On July 31, 1999, Dempsey married makeup artist Jillian Fink. The couple have three children. In January 2015, Fink filed for divorce, but
9504-532: Was named as People's Sexiest Man Alive in 2023. Dempsey started his career acting in films such as Can't Buy Me Love (1987) and Loverboy (1989). He has since starred in several romantic comedy films such as Sweet Home Alabama (2002), Made of Honor (2008), Valentine's Day (2010), and Bridget Jones's Baby (2016). Dempsey has also taken dramatic roles in Outbreak (1995), Scream 3 (2000), Freedom Writers (2007), Transformers: Dark of
9603-508: Was never very mature in my relationships with women. First sign of conflict, I was gone. Wouldn't discuss it, because I was afraid it would lead to an argument." This stemmed from a fear of having an unhappy marriage like the one his parents had, though Mahoney did previously have "several long-term relationships". He was a Catholic who called Christianity "probably the most important facet of my life": before each of his performances, he would pray "Most glorious blessed spirit, I thank you for all
9702-583: Was succeeded by Jeff Bennett in The Emperor's New School for an unknown reason). In 2007, Mahoney provided the voice of Dr. Robert Terwilliger, Sr. ( Sideshow Bob 's father) in The Simpsons episode " Funeral for a Fiend ". This reunited him with his Frasier co-stars Kelsey Grammer (Sideshow Bob) and David Hyde Pierce (Cecil, Sideshow Bob's brother). Mahoney co-starred as the Old Man in
9801-421: Was working on two small-screen projects: a drama The Limit for SundanceTV and a travelogue spy thriller called Fodors . He said: I would love to do something else. I'm going to take the rest of the year off to develop. I would like to be a producer. I would commit to a show that is 10 to 12 episodes. But 24 again, I don't know if I would do that. It's a very hard life. It's financially rewarding but there comes
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