The Externals are a group of fictional characters appearing in American comic books published by Marvel Comics . Considered a rare subspecies of mutants , most of them were X-Men antagonists . The original, unused name for the group was to be The Prophets, as seen on the back of the Sunspot & Gideon trading card included with X-Force #1. The characters first appeared in X-Force #10 (May 1992).
125-600: The Externals are all mutants with the additional gift of immortality and, as expressed by Cable , they play an important role in Apocalypse 's rise to power at least in one future. Their true origins are scattered throughout history, but it is known that they all share a psychic link with each other that separates them from other immortals. This psychic connection allows them to not only sense each other and their whereabouts, but allows them to summon each other at will from great distances. They also can sense when one rises from
250-510: A futurist and transhumanist , stated in his book The Singularity Is Near that he believes that advanced medical nanorobotics could completely remedy the effects of aging by 2030. According to Richard Feynman , it was his former graduate student and collaborator Albert Hibbs who originally suggested to him (circa 1959) the idea of a medical use for Feynman's theoretical micromachines (see biological machine ). Hibbs suggested that certain repair machines might one day be reduced in size to
375-423: A mutation–selection balance . It is predicted that a viral quasispecies at a low but evolutionarily neutral and highly connected (that is, flat) region in the fitness landscape will outcompete a quasispecies located at a higher but narrower fitness peak in which the surrounding mutants are unfit, "the quasispecies effect" or the "survival of the flattest". There is no suggestion that a viral quasispecies resembles
500-476: A "cap" at the end of DNA, are thought to be the cause of cell aging. Every time a cell divides the telomere becomes a bit shorter; when it is finally worn down, the cell is unable to split and dies. Telomerase is an enzyme which rebuilds the telomeres in stem cells and cancer cells, allowing them to replicate an infinite number of times. No definitive work has yet demonstrated that telomerase can be used in human somatic cells to prevent healthy tissues from aging. On
625-400: A "classical" method of determining species, such as with Linnaeus, early in evolutionary theory. However, different phenotypes are not necessarily different species (e.g. a four-winged Drosophila born to a two-winged mother is not a different species). Species named in this manner are called morphospecies . In the 1970s, Robert R. Sokal , Theodore J. Crovello and Peter Sneath proposed
750-424: A 'smallest clade' idea" (a phylogenetic species concept). Mishler and Wilkins and others concur with this approach, even though this would raise difficulties in biological nomenclature. Wilkins cited the ichthyologist Charles Tate Regan 's early 20th century remark that "a species is whatever a suitably qualified biologist chooses to call a species". Wilkins noted that the philosopher Philip Kitcher called this
875-436: A computer system, and exist indefinitely in a virtual environment. This could be accomplished via advanced cybernetics, where computer hardware would initially be installed in the brain to help sort memory or accelerate thought processes. Components would be added gradually until the person's entire brain functions were handled by artificial devices, avoiding sharp transitions that would lead to issues of identity , thus running
1000-428: A connected series of neighbouring populations, each of which can sexually interbreed with adjacent related populations, but for which there exist at least two "end" populations in the series, which are too distantly related to interbreed, though there is a potential gene flow between each "linked" population. Such non-breeding, though genetically connected, "end" populations may co-exist in the same region thus closing
1125-438: A continuous physical life is to be maintained. This aversion to trauma risk to the brain would naturally result in significant behavioral changes that would render physical immortality undesirable for some people. Organisms otherwise unaffected by these causes of death would still face the problem of obtaining sustenance (whether from currently available agricultural processes or from hypothetical future technological processes) in
1250-466: A copy of the original mind, and not the conscious mind of the living entity associated in such a transfer. Without a simultaneous upload of consciousness, the original living entity remains mortal, thus not achieving true immortality. Research on neural correlates of consciousness is yet inconclusive on this issue. Whatever the route to mind upload, persons in this state could then be considered essentially immortal, short of loss or traumatic destruction of
1375-610: A cyborg. Some people believe that such modifications would make one impervious to aging and disease and theoretically immortal unless killed or destroyed. As late as 1952, the editorial staff of the Syntopicon found in their compilation of the Great Books of the Western World , that "The philosophical issue concerning immortality cannot be separated from issues concerning the existence and nature of man's soul." Thus,
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#17327809756351500-432: A different species from its ancestors. Viruses have enormous populations, are doubtfully living since they consist of little more than a string of DNA or RNA in a protein coat, and mutate rapidly. All of these factors make conventional species concepts largely inapplicable. A viral quasispecies is a group of genotypes related by similar mutations, competing within a highly mutagenic environment, and hence governed by
1625-466: A few had made their presence known as soldiers of Apocalypse. Candra, Selene and Gideon were recruited as the first wave of Horsemen of Apocalypse. Immortality Immortality is the concept of eternal life. Some species possess ' biological immortality ' due to an apparent lack of the Hayflick limit . Some scientists, futurists and philosophers have theorized about the immortality of
1750-416: A future physical resurrection ), proclaims an amalgamated view of resurrected believers where both the physical and the spiritual are rebuilt in the likeness of post-resurrection Christ, who "will transform our lowly body to be like his glorious body" (ESV). This thought mirrors Paul's depiction of believers having been "buried therefore with him [that is, Christ] by baptism into death" (ESV). N.T. Wright ,
1875-508: A genetic boundary suitable for defining a species concept is present. DNA barcoding has been proposed as a way to distinguish species suitable even for non-specialists to use. One of the barcodes is a region of mitochondrial DNA within the gene for cytochrome c oxidase . A database, Barcode of Life Data System , contains DNA barcode sequences from over 190,000 species. However, scientists such as Rob DeSalle have expressed concern that classical taxonomy and DNA barcoding, which they consider
2000-465: A lineage should be divided into multiple chronospecies , or when populations have diverged to have enough distinct character states to be described as cladistic species. Species and higher taxa were seen from the time of Aristotle until the 18th century as categories that could be arranged in a hierarchy, the great chain of being . In the 19th century, biologists grasped that species could evolve given sufficient time. Charles Darwin 's 1859 book On
2125-656: A living, breathing conscious body, rather than to an immortal soul. In the New Testament, the Greek word traditionally translated "soul" ( ψυχή ) has substantially the same meaning as the Hebrew, without reference to an immortal soul. "Soul" may refer either to the whole person, the self, as in "three thousand souls " were converted in Acts 2:41 (see Acts 3:23 ). The Hebrew Bible speaks about Sheol (שאול), originally
2250-492: A misnomer, need to be reconciled, as they delimit species differently. Genetic introgression mediated by endosymbionts and other vectors can further make barcodes ineffective in the identification of species. A phylogenetic or cladistic species is "the smallest aggregation of populations (sexual) or lineages (asexual) diagnosable by a unique combination of character states in comparable individuals (semaphoronts)". The empirical basis – observed character states – provides
2375-402: A nanorobotics theorist, suggests tiny medical nanorobots could be created to go through human bloodstreams, find dangerous things like cancer cells and bacteria, and destroy them. Freitas anticipates that gene-therapies and nanotechnology will eventually make the human body effectively self-sustainable and capable of living indefinitely in empty space, short of severe brain trauma. This supports
2500-484: A new creation" , he said. Christian apocrypha include immortal human figures such as Cartaphilus who were cursed with physical immortality for various transgressions against Christ during the Passion. The medieval Waldensians believed in the immortality of the soul. Leaders of sects such as John Asgill and John Wroe taught followers that physical immortality was possible. Many Patristic writers have connected
2625-449: A particular species, including which genus (and higher taxa) it is placed in, is a hypothesis about the evolutionary relationships and distinguishability of that group of organisms. As further information comes to hand, the hypothesis may be corroborated or refuted. Sometimes, especially in the past when communication was more difficult, taxonomists working in isolation have given two distinct names to individual organisms later identified as
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#17327809756352750-400: A perfect model of life, it is still a useful tool to scientists and conservationists for studying life on Earth, regardless of the theoretical difficulties. If species were fixed and clearly distinct from one another, there would be no problem, but evolutionary processes cause species to change. This obliges taxonomists to decide, for example, when enough change has occurred to declare that
2875-400: A short way of saying that something applies to many species within a genus, but not to all. If scientists mean that something applies to all species within a genus, they use the genus name without the specific name or epithet. The names of genera and species are usually printed in italics . However, abbreviations such as "sp." should not be italicised. When a species' identity is not clear,
3000-451: A solution to each of these causes, a program de Grey calls engineered negligible senescence . There is also a huge body of knowledge indicating that change is characterized by the loss of molecular fidelity. Disease is theoretically surmountable by technology. In short, it is an abnormal condition affecting the body of an organism, something the body should not typically have to deal with its natural make up. Human understanding of genetics
3125-404: A specialist may use "cf." before the epithet to indicate that confirmation is required. The abbreviations "nr." (near) or "aff." (affine) may be used when the identity is unclear but when the species appears to be similar to the species mentioned after. With the rise of online databases, codes have been devised to provide identifiers for species that are already defined, including: The naming of
3250-523: A species as groups of actually or potentially interbreeding natural populations, which are reproductively isolated from other such groups. It has been argued that this definition is a natural consequence of the effect of sexual reproduction on the dynamics of natural selection. Mayr's use of the adjective "potentially" has been a point of debate; some interpretations exclude unusual or artificial matings that occur only in captivity, or that involve animals capable of mating but that do not normally do so in
3375-400: A species as determined by a taxonomist. A typological species is a group of organisms in which individuals conform to certain fixed properties (a type), so that even pre-literate people often recognise the same taxon as do modern taxonomists. The clusters of variations or phenotypes within specimens (such as longer or shorter tails) would differentiate the species. This method was used as
3500-491: A species. All species definitions assume that an organism acquires its genes from one or two parents very like the "daughter" organism, but that is not what happens in HGT. There is strong evidence of HGT between very dissimilar groups of prokaryotes , and at least occasionally between dissimilar groups of eukaryotes , including some crustaceans and echinoderms . The evolutionary biologist James Mallet concludes that there
3625-685: A species. Generally the term includes the unknown element of a distinct act of creation. Many authors have argued that a simple textbook definition, following Mayr's concept, works well for most multi-celled organisms , but breaks down in several situations: Species identification is made difficult by discordance between molecular and morphological investigations; these can be categorised as two types: (i) one morphology, multiple lineages (e.g. morphological convergence , cryptic species ) and (ii) one lineage, multiple morphologies (e.g. phenotypic plasticity , multiple life-cycle stages). In addition, horizontal gene transfer (HGT) makes it difficult to define
3750-463: A stasis chamber living either a constant dream of winning for Selene and a constant nightmare for the others. On Earth-4935 (Askani World), the Externals were purged by Apocalypse, who ascended to power and took control of the planet up until the 39th century. When the time-traveling Legion killed his own father and created an alternate reality, it is unknown what happened to the Externals, as only
3875-462: A subject of research and debate. Programmed cell death and the telomere "end replication problem" are found even in the earliest and simplest of organisms. This may be a tradeoff between selecting for cancer and selecting for aging. Modern theories on the evolution of aging include the following: Individual organisms ordinarily age and die, while the germlines which connect successive generations are potentially immortal. The basis for this difference
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4000-653: A synonym of the grave – the repository of the dead or the cessation of existence, until the resurrection of the dead . This doctrine of resurrection is mentioned explicitly only in Daniel 12:1–4 although it may be implied in several other texts. New theories arose concerning Sheol during the intertestamental period . The views about immortality in Judaism is perhaps best exemplified by the various references to this in Second Temple period . The concept of resurrection of
4125-528: A taxonomic decision at the discretion of cognizant specialists, is not governed by the Codes of Zoological or Botanical Nomenclature, in contrast to the PhyloCode , and contrary to what is done in several other fields, in which the definitions of technical terms, like geochronological units and geopolitical entities, are explicitly delimited. The nomenclatural codes that guide the naming of species, including
4250-485: A theologian and former Bishop of Durham , has said many people forget the physical aspect of what Jesus promised. He told Time : "Jesus' resurrection marks the beginning of a restoration that he will complete upon his return . Part of this will be the resurrection of all the dead , who will 'awake', be embodied and participate in the renewal. Wright says John Polkinghorne , a physicist and a priest, has put it this way: 'God will download our software onto his hardware until
4375-517: A traditional biological species. The International Committee on Taxonomy of Viruses has since 1962 developed a universal taxonomic scheme for viruses; this has stabilised viral taxonomy. Most modern textbooks make use of Ernst Mayr 's 1942 definition, known as the Biological Species Concept as a basis for further discussion on the definition of species. It is also called a reproductive or isolation concept. This defines
4500-447: A variation on the morphological species concept, a phenetic species, defined as a set of organisms with a similar phenotype to each other, but a different phenotype from other sets of organisms. It differs from the morphological species concept in including a numerical measure of distance or similarity to cluster entities based on multivariate comparisons of a reasonably large number of phenotypic traits. A mate-recognition species
4625-515: A variety of reasons. Viruses are a special case, driven by a balance of mutation and selection , and can be treated as quasispecies . Biologists and taxonomists have made many attempts to define species, beginning from morphology and moving towards genetics . Early taxonomists such as Linnaeus had no option but to describe what they saw: this was later formalised as the typological or morphological species concept. Ernst Mayr emphasised reproductive isolation, but this, like other species concepts,
4750-438: Is "an entity composed of organisms which maintains its identity from other such entities through time and over space, and which has its own independent evolutionary fate and historical tendencies". This differs from the biological species concept in embodying persistence over time. Wiley and Mayden stated that they see the evolutionary species concept as "identical" to Willi Hennig 's species-as-lineages concept, and asserted that
4875-415: Is a fundamental problem in biology. The Russian biologist and historian Zhores A. Medvedev considered that the accuracy of genome replicative and other synthetic systems alone cannot explain the immortality of germlines . Rather Medvedev thought that known features of the biochemistry and genetics of sexual reproduction indicate the presence of unique information maintenance and restoration processes at
5000-400: Is a group of sexually reproducing organisms that recognise one another as potential mates. Expanding on this to allow for post-mating isolation, a cohesion species is the most inclusive population of individuals having the potential for phenotypic cohesion through intrinsic cohesion mechanisms; no matter whether populations can hybridise successfully, they are still distinct cohesion species if
5125-458: Is a set of organisms adapted to a particular set of resources, called a niche, in the environment. According to this concept, populations form the discrete phenetic clusters that we recognise as species because the ecological and evolutionary processes controlling how resources are divided up tend to produce those clusters. A genetic species as defined by Robert Baker and Robert Bradley is a set of genetically isolated interbreeding populations. This
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5250-522: Is a state of life that allows a person to avoid death and maintain conscious thought. It can mean the unending existence of a person from a physical source other than organic life, such as a computer. Pursuit of physical immortality before the advent of modern science included alchemists , who sought to create the Philosopher's Stone , and various cultures' legends such as the Fountain of Youth or
5375-406: Is also a state that the gods at times offer humans. In Christianity , the conviction that God may offer physical immortality with the resurrection of the flesh at the end of time has traditionally been at the center of its beliefs. What form an unending human life would take, or whether an immaterial soul exists and possesses immortality, has been a major point of focus of religion, as well as
5500-414: Is called speciation . Charles Darwin was the first to describe the role of natural selection in speciation in his 1859 book The Origin of Species . Speciation depends on a measure of reproductive isolation , a reduced gene flow. This occurs most easily in allopatric speciation, where populations are separated geographically and can diverge gradually as mutations accumulate. Reproductive isolation
5625-412: Is called the specific name or the specific epithet (in botanical nomenclature , also sometimes in zoological nomenclature ). For example, Boa constrictor is one of the species of the genus Boa , with constrictor being the species' epithet. While the definitions given above may seem adequate at first glance, when looked at more closely they represent problematic species concepts. For example,
5750-403: Is described formally, in a publication that assigns it a unique scientific name. The description typically provides means for identifying the new species, which may not be based solely on morphology (see cryptic species ), differentiating it from other previously described and related or confusable species and provides a validly published name (in botany) or an available name (in zoology) when
5875-671: Is further weakened by the existence of microspecies , groups of organisms, including many plants, with very little genetic variability, usually forming species aggregates . For example, the dandelion Taraxacum officinale and the blackberry Rubus fruticosus are aggregates with many microspecies—perhaps 400 in the case of the blackberry and over 200 in the dandelion, complicated by hybridisation , apomixis and polyploidy , making gene flow between populations difficult to determine, and their taxonomy debatable. Species complexes occur in insects such as Heliconius butterflies, vertebrates such as Hypsiboas treefrogs, and fungi such as
6000-528: Is gardens, beneath which rivers flow. Every time they are fed with fruits therefrom, they say, 'Why, this is what we were fed with before,' for they are given things in similitude; and they have therein companions pure (and holy); and they abide therein forever." In contrast, the kafir hold the contradictory notion that they abide in Jahannam perpetually. Angels in Islam are reckoned as immortals from
6125-459: Is given a long life but not immortality or there is more than a little argument stated about the demise of khidr ; however, it is the matter of debate, and there is a fabrication point that goes around the Khidr drank from the fountain of Life , which is thoroughly invalid. Jesus in Islam was summoned to the sky by Allah's sanction to preserve him from the cross and endow him with long life until
6250-726: Is hard or even impossible to test. Later biologists have tried to refine Mayr's definition with the recognition and cohesion concepts, among others. Many of the concepts are quite similar or overlap, so they are not easy to count: the biologist R. L. Mayden recorded about 24 concepts, and the philosopher of science John Wilkins counted 26. Wilkins further grouped the species concepts into seven basic kinds of concepts: (1) agamospecies for asexual organisms (2) biospecies for reproductively isolated sexual organisms (3) ecospecies based on ecological niches (4) evolutionary species based on lineage (5) genetic species based on gene pool (6) morphospecies based on form or phenotype and (7) taxonomic species,
6375-433: Is indeed possible for a creature to be biologically immortal , these are animals which are physiologically very different from humans, and it is not known if something comparable will ever be possible for humans. Immortality in religion refers usually to either the belief in physical immortality or a more spiritual afterlife . In traditions such as ancient Egyptian beliefs, Mesopotamian beliefs and ancient Greek beliefs,
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#17327809756356500-538: Is later revealed by Summoner, the grandson of Apocalypse through his daughter War, and Apocalypse's wife Genesis (Summoner's grandmother and War's mother) that the mutant known as the "White Sword" is also an External. White Sword is the Champion of Okkara (the living continent that was once the single mutant homeland on Earth) and an Omega-level healer, and leads an arm of One Hundred Champions, composed of warriors he has personally defeated and then resurrected. Following
6625-731: Is leading to cures and treatments for a myriad of previously incurable diseases. The mechanisms by which other diseases do damage are becoming better understood. Sophisticated methods of detecting diseases early are being developed. Preventative medicine is becoming better understood. Neurodegenerative diseases like Parkinson's and Alzheimer's may soon be curable with the use of stem cells . Breakthroughs in cell biology and telomere research are leading to treatments for cancer. Vaccines are being researched for AIDS and tuberculosis . Genes associated with type 1 diabetes and certain types of cancer have been discovered, allowing for new therapies to be developed. Artificial devices attached directly to
6750-403: Is no easy way to tell whether related geographic or temporal forms belong to the same or different species. Species gaps can be verified only locally and at a point of time. One is forced to admit that Darwin's insight is correct: any local reality or integrity of species is greatly reduced over large geographic ranges and time periods. The botanist Brent Mishler argued that the species concept
6875-478: Is not valid, notably because gene flux decreases gradually rather than in discrete steps, which hampers objective delimitation of species. Indeed, complex and unstable patterns of gene flux have been observed in cichlid teleosts of the East African Great Lakes . Wilkins argued that "if we were being true to evolution and the consequent phylogenetic approach to taxa, we should replace it with
7000-586: Is similar to Mayr's Biological Species Concept, but stresses genetic rather than reproductive isolation. In the 21st century, a genetic species could be established by comparing DNA sequences. Earlier, other methods were available, such as comparing karyotypes (sets of chromosomes ) and allozymes ( enzyme variants). An evolutionarily significant unit (ESU) or "wildlife species" is a population of organisms considered distinct for purposes of conservation. In palaeontology , with only comparative anatomy (morphology) and histology from fossils as evidence,
7125-594: Is threatened by hybridisation, but this can be selected against once a pair of populations have incompatible alleles of the same gene, as described in the Bateson–Dobzhansky–Muller model . A different mechanism, phyletic speciation, involves one lineage gradually changing over time into a new and distinct form (a chronospecies ), without increasing the number of resultant species. Horizontal gene transfer between organisms of different species, either through hybridisation , antigenic shift , or reassortment ,
7250-419: Is warranted in exploiting this property, as exactly this same unbounded growth is a crucial step in enabling cancerous growth. If an organism can replicate its body cells faster, then it would theoretically stop aging. Embryonic stem cells express telomerase, which allows them to divide repeatedly and form the individual. In adults, telomerase is highly expressed in cells that need to divide regularly (e.g., in
7375-694: The Dead Sea scrolls texts. Both Josephus and the New Testament record that the Sadducees did not believe in an afterlife , but the sources vary on the beliefs of the Pharisees . The New Testament claims that the Pharisees believed in the resurrection, but does not specify whether this included the flesh or not. According to Josephus , who himself was a Pharisee, the Pharisees held that only
7500-530: The ICZN for animals and the ICN for plants, do not make rules for defining the boundaries of the species. Research can change the boundaries, also known as circumscription, based on new evidence. Species may then need to be distinguished by the boundary definitions used, and in such cases the names may be qualified with sensu stricto ("in the narrow sense") to denote usage in the exact meaning given by an author such as
7625-520: The Peaches of Immortality inspiring attempts at discovering an elixir of life . Modern scientific trends, such as cryonics , digital immortality , breakthroughs in rejuvenation , or predictions of an impending technological singularity , to achieve genuine human physical immortality, must still overcome all causes of death to succeed. There are three main causes of death: natural aging , disease , and injury . Such issues can be resolved with
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#17327809756357750-401: The chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. About 14% of these had been described by 2011. All species (except viruses ) are given a two-part name , called a "binomial". The first part of a binomial is the genus to which the species belongs. The second part
7875-399: The fly agaric . Natural hybridisation presents a challenge to the concept of a reproductively isolated species, as fertile hybrids permit gene flow between two populations. For example, the carrion crow Corvus corone and the hooded crow Corvus cornix appear and are classified as separate species, yet they can hybridise where their geographical ranges overlap. A ring species is
8000-507: The jaguar ( Panthera onca ) of Latin America or the leopard ( Panthera pardus ) of Africa and Asia. In contrast, the scientific names of species are chosen to be unique and universal (except for some inter-code homonyms ); they are in two parts used together : the genus as in Puma , and the specific epithet as in concolor . A species is given a taxonomic name when a type specimen
8125-583: The nervous system may restore sight to the blind. Drugs are being developed to treat a myriad of other diseases and ailments. Physical trauma would remain as a threat to perpetual physical life, as an otherwise immortal person would still be subject to unforeseen accidents or catastrophes. The speed and quality of paramedic response remains a determining factor in surviving severe trauma. A body that could automatically repair itself from severe trauma, such as speculated uses for nanotechnology , would mitigate this factor. The brain cannot be risked to trauma if
8250-406: The "cynical species concept", and arguing that far from being cynical, it usefully leads to an empirical taxonomy for any given group, based on taxonomists' experience. Other biologists have gone further and argued that we should abandon species entirely, and refer to the "Least Inclusive Taxonomic Units" (LITUs), a view that would be coherent with current evolutionary theory. The species concept
8375-532: The Eternal Caldera on Krakoa, revealing his intentions to sacrifice some of their life energy to power the Arak Maw Gate. Selene, Gideon and Absolom are revealed to be a part of his plan and quickly turns on their fellow immortals. With the unexpected help of Rictor, the group wiped out four of the Externals and extracted their life energy to fuel the crystals that powered the gateway to Arakko. It
8500-719: The Fall , although this initial "imperishability of the bodily frame of man" was "a preternatural condition". Christians who profess the Nicene Creed believe that every dead person (whether they believed in Christ or not) will be resurrected from the dead at the Second Coming ; this belief is known as universal resurrection . Paul the Apostle , in following his past life as a Pharisee (a Jewish social movement that held to
8625-568: The High Lords' gatherings. Each External was claimed to represent an intangible concept: At one point, X-Men regular and former New Mutant Cannonball was declared an External by Cable, after he was killed by Sauron. His revival was sensed by the other Externals who declared that he represented hope. Later, Selene betrayed her fellow Externals and despite the efforts of X-Force, she managed to slay them by absorbing their life forces. Selene ultimately escaped, but not before summarily dismissing
8750-709: The Mutant Massacre at the Hellfire Gala, the mutant population of Earth was scattered. Although she had been working with Sebastian Shaw and Orchis for a time, Selene eventually returned to her base in Nova Roma, where she began using Absalom, Burke, Gideon to gather in mutants from across the global in order to achieve Dominionhood. This garnered the attention of the X-Corps in which a battle ensued that left Selene, Saul, Absalom, Crule, and Nicodemus trapped in
8875-626: The Origin of Species explained how species could arise by natural selection . That understanding was greatly extended in the 20th century through genetics and population ecology . Genetic variability arises from mutations and recombination , while organisms themselves are mobile, leading to geographical isolation and genetic drift with varying selection pressures . Genes can sometimes be exchanged between species by horizontal gene transfer ; new species can arise rapidly through hybridisation and polyploidy ; and species may become extinct for
9000-405: The abbreviation "sp." in the singular or "spp." (standing for species pluralis , Latin for "multiple species") in the plural in place of the specific name or epithet (e.g. Canis sp.). This commonly occurs when authors are confident that some individuals belong to a particular genus but are not sure to which exact species they belong, as is common in paleontology . Authors may also use "spp." as
9125-399: The accompanying stress. Selene's assumptions about Cannonball and Apocalypse's status as Externals also cannot be taken as fact, as she incorrectly describes a total of seven Externals, rather than eight. Evidently, as long as there are at least two living Externals in a single timeframe, those who have died will simply be revived to life and health, as was the case with Burke, who was killed by
9250-506: The advanced industrial societies are already markedly longer than those of the past because of better nutrition, availability of health care, standard of living and bio-medical scientific advances. Technological immortality predicts further progress for the same reasons over the near term. An important aspect of current scientific thinking about immortality is that some combination of human cloning , cryonics or nanotechnology will play an essential role in extreme life extension. Robert Freitas ,
9375-580: The advent of the Dajjal . Dajjal is, additionally, given a long life. Jesus Christ dispatches the Dajjal as he stays after 40 days, one like a year, one like a month, one like a week, and the rest of his days like normal days. The Qur'an states that it is the ultimate fate of all life, including humans , to die eventually. كُلُّ نَفْسٍ ذَائِقَةُ الْمَوْتِ (Every soul will taste death) The traditional concept of an immaterial and immortal soul distinct from
9500-570: The amount of hybridisation is insufficient to completely mix their respective gene pools . A further development of the recognition concept is provided by the biosemiotic concept of species. In microbiology , genes can move freely even between distantly related bacteria, possibly extending to the whole bacterial domain. As a rule of thumb, microbiologists have assumed that members of Bacteria or Archaea with 16S ribosomal RNA gene sequences more similar than 97% to each other need to be checked by DNA–DNA hybridisation to decide if they belong to
9625-515: The amount or proportion of telomerase in the body, a naturally forming enzyme that helps maintain the protective caps at the ends of chromosomes , could prevent cells from dying and so may ultimately lead to extended, healthier lifespans. A team of researchers at the Spanish National Cancer Centre ( Madrid ) tested the hypothesis on mice. It was found that those mice which were " genetically engineered to produce 10 times
9750-404: The appropriate sexes or mating types can produce fertile offspring , typically by sexual reproduction . It is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity . Other ways of defining species include their karyotype , DNA sequence, morphology , behaviour, or ecological niche . In addition, paleontologists use the concept of
9875-414: The assumption that Cannonball was an External, calling into question Cable's conclusion and the reasons for it. Yet, later Cannonball was shot three times through the chest by Reverend Stryker's Purifiers , and was back up and around in a matter of hours. When asked about it, Hank McCoy mentioned Cannonball's status as an immortal again, though it is not sure if he was joking or not. Originally, Apocalypse
10000-474: The biological species concept, "the several versions" of the phylogenetic species concept, and the idea that species are of the same kind as higher taxa are not suitable for biodiversity studies (with the intention of estimating the number of species accurately). They further suggested that the concept works for both asexual and sexually-reproducing species. A version of the concept is Kevin de Queiroz 's "General Lineage Concept of Species". An ecological species
10125-505: The biological species concept, a cladistic species does not rely on reproductive isolation – its criteria are independent of processes that are integral in other concepts. Therefore, it applies to asexual lineages. However, it does not always provide clear cut and intuitively satisfying boundaries between taxa, and may require multiple sources of evidence, such as more than one polymorphic locus, to give plausible results. An evolutionary species, suggested by George Gaylord Simpson in 1951,
10250-687: The body was not found in Judaism before the Babylonian exile , but developed as a result of interaction with Persian and Hellenistic philosophies . Accordingly, the Hebrew word nephesh , although translated as "soul" in some older English-language Bibles, actually has a meaning closer to "living being". Nephesh was rendered in the Septuagint as ψυχή ( psūchê ), the Greek word for 'soul'. The only Hebrew word traditionally translated "soul" ( nephesh ) in English language Bibles refers to
10375-428: The boundaries between closely related species become unclear with hybridisation , in a species complex of hundreds of similar microspecies , and in a ring species . Also, among organisms that reproduce only asexually , the concept of a reproductive species breaks down, and each clone is potentially a microspecies. Although none of these are entirely satisfactory definitions, and while the concept of species may not be
10500-433: The concept of a chronospecies can be applied. During anagenesis (evolution, not necessarily involving branching), some palaeontologists seek to identify a sequence of species, each one derived from the phyletically extinct one before through continuous, slow and more or less uniform change. In such a time sequence, some palaeontologists assess how much change is required for a morphologically distinct form to be considered
10625-404: The dead and when one is killed. Saul, Absalom, Gideon, Nicodemus, Burke, Selene, Candra, and Crule (to a lesser extent) formed the self-fashioned "High Lords", bent on playing power games and manipulating events behind the scenes. Crule was employed as an enforcer and assassin for the other High Lords, while Candra and Selene preferred to play their own schemes separately and did not take any part in
10750-459: The death of a certain individual, it will be arbitrated consistent with its beliefs as well as actions and will embark on the ever-lasting place where they will abate. The Muslim who holds the five pillars of Islam will make an entrance into the Jannah , where they will inhabit eternally. Al-Baqarah (2:25): "But give glad tidings to those who believe and work righteousness, that their portion
10875-491: The different stages of gametogenesis . In particular, Medvedev considered that the most important opportunities for information maintenance of germ cells are created by recombination during meiosis and DNA repair ; he saw these as processes within the germ cells that were capable of restoring the integrity of DNA and chromosomes from the types of damage that cause irreversible aging in somatic cells . Chemical Neurological Some scientists believe that boosting
11000-424: The entire structure in a computer. What level of detail such scans and simulations would need to achieve to emulate awareness, and whether the scanning process would destroy the brain, is still to be determined. It is suggested that achieving immortality through this mechanism would require specific consideration to be given to the role of consciousness in the functions of the mind . An uploaded mind would only be
11125-435: The evidence to support hypotheses about evolutionarily divergent lineages that have maintained their hereditary integrity through time and space. Molecular markers may be used to determine diagnostic genetic differences in the nuclear or mitochondrial DNA of various species. For example, in a study done on fungi , studying the nucleotide characters using cladistic species produced the most accurate results in recognising
11250-431: The existence of biologically immortal species demonstrates, there is no thermodynamic necessity for senescence: a defining feature of life is that it takes in free energy from the environment and unloads its entropy as waste. Living systems can even build themselves up from seed, and routinely repair themselves. Aging is therefore presumed to be a byproduct of evolution , but why mortality should be selected for remains
11375-418: The face of changing availability of suitable resources as environmental conditions change. After avoiding aging, disease, and trauma, death through resource limitation is still possible, such as hypoxia or starvation . If there is no limitation on the degree of gradual mitigation of risk then it is possible that the cumulative probability of death over an infinite horizon is less than certainty , even when
11500-440: The future after cures to the patients' diseases have been discovered and aging is reversible . Modern cryonics procedures use a process called vitrification which creates a glass-like state rather than freezing as the body is brought to low temperatures. This process reduces the risk of ice crystals damaging the cell-structure, which would be especially detrimental to cell structures in the brain, as their minute adjustment evokes
11625-432: The future version of Gideon only to be reborn as a baby with purple eyes because the present versions of Selene and Gideon were alive. More recently, it was confirmed that Apocalypse is indeed an External, and participated in the creation of Candra's gem with Selene and the other High lords eons ago. Following the creation of a mutant nation on Krakoa, Apocalypse rescued his first Horsemen. He summoned his fellow Externals to
11750-498: The human body, with some suggesting that human immortality may be achievable in the first few decades of the 21st century with the help of certain technologies such as mind uploading ( digital immortality ). Other advocates believe that life extension is a more achievable goal in the short term, with immortality awaiting further research breakthroughs. The absence of aging would provide humans with biological immortality, but not invulnerability to death by disease or injury . Whether
11875-464: The immortal gods consequently were considered to have physical bodies. In Mesopotamian and Greek religion, the gods also made certain men and women physically immortal, whereas in Christianity, many believe that all true believers will be resurrected to physical immortality. Similar beliefs that physical immortality is possible are held by Rastafarians or Rebirthers . Physical immortality
12000-482: The immortal rational soul to the image of God found in Genesis 1:26. Among them is Athanasius of Alexandria and Clement of Alexandria, who say that the immortal rational soul itself is the image of God. Even Early Christian Liturgies exhibit this connection between the immortal rational soul and the creation of humanity in the image of God. Islamic beliefs bears the concept of spiritual immortality within it; following
12125-408: The immune system), whereas most somatic cells express it only at very low levels in a cell-cycle dependent manner. Technological immortality is the prospect for much longer life spans made possible by scientific advances in a variety of fields: nanotechnology, emergency room procedures, genetics, biological engineering , regenerative medicine , microbiology , and others. Contemporary life spans in
12250-417: The individual's mind. One idea that has been advanced involves uploading an individual's habits and memories via direct mind-computer interface . The individual's memory may be loaded to a computer or to a new organic body. Extropian futurists like Moravec and Kurzweil have proposed that, thanks to exponentially growing computing power, it will someday be possible to upload human consciousness onto
12375-447: The machines that maintained them. Transforming a human into a cyborg can include brain implants or extracting a human processing unit and placing it in a robotic life-support system. Even replacing biological organs with robotic ones could increase life span (e.g. pace makers) and depending on the definition, many technological upgrades to the body, like genetic modifications or the addition of nanobots would qualify an individual as
12500-435: The normal levels of telomerase lived 50% longer than normal mice". In normal circumstances, without the presence of telomerase, if a cell divides repeatedly, at some point all the progeny will reach their Hayflick limit . With the presence of telomerase, each dividing cell can replace the lost bit of DNA , and any single cell can then divide unbounded. While this unbounded growth property has excited many researchers, caution
12625-483: The numerous fungi species of all the concepts studied. Versions of the phylogenetic species concept that emphasise monophyly or diagnosability may lead to splitting of existing species, for example in Bovidae , by recognising old subspecies as species, despite the fact that there are no reproductive barriers, and populations may intergrade morphologically. Others have called this approach taxonomic inflation , diluting
12750-458: The other hand, scientists hope to be able to grow organs with the help of stem cells, allowing organ transplants without the risk of rejection, another step in extending human life expectancy. These technologies are the subject of ongoing research, and are not yet realized. Life defined as biologically immortal is still susceptible to causes of death besides aging, including disease and trauma, as defined above. Notable immortal species include: As
12875-593: The paper is accepted for publication. The type material is usually held in a permanent repository, often the research collection of a major museum or university, that allows independent verification and the means to compare specimens. Describers of new species are asked to choose names that, in the words of the International Code of Zoological Nomenclature , are "appropriate, compact, euphonious, memorable, and do not cause offence". Books and articles sometimes intentionally do not identify species fully, using
13000-674: The person who named the species, while the antonym sensu lato ("in the broad sense") denotes a wider usage, for instance including other subspecies. Other abbreviations such as "auct." ("author"), and qualifiers such as "non" ("not") may be used to further clarify the sense in which the specified authors delineated or described the species. Species are subject to change, whether by evolving into new species, exchanging genes with other species, merging with other species or by becoming extinct. The evolutionary process by which biological populations of sexually-reproducing organisms evolve to become distinct or reproductively isolated as species
13125-486: The perspective of Islam but most people believe is that the angels will die and that the Angel of Death will die, but there is no clear text concerning this. Rather there are texts which may indicate this, and there is the well known hadeeth (narration) about the "trumpet", which is a munkar hadeeth (rejected report). alternatively, Jinn have a long lifespan between 1000 and 1500. In some Muslim Sufi mystics, Khidr
13250-460: The physical body is found in 2 Maccabees , according to which it will happen through recreation of the flesh. Resurrection of the dead is specified in detail in the extra-canonical books of Enoch , and in Apocalypse of Baruch . According to the British scholar in ancient Judaism P.R. Davies , there is "little or no clear reference ... either to immortality or to resurrection from the dead" in
13375-672: The point that it would, in theory, be possible to (as Feynman put it) "swallow the doctor". The idea was incorporated into Feynman's 1959 essay There's Plenty of Room at the Bottom . Cryonics , the practice of preserving organisms (either intact specimens or only their brains) for possible future revival by storing them at cryogenic temperatures where metabolism and decay are almost completely stopped, can be used to 'pause' for those who believe that life extension technologies will not develop sufficiently within their lifetime. Ideally, cryonics would allow clinically dead people to be brought back in
13500-405: The process of internal immortality is delivered within the upcoming years depends chiefly on research (and in neuron research in the case of internal immortality through an immortalized cell line) in the former view and perhaps is an awaited goal in the latter case. From at least the time of the ancient Mesopotamians , there has been a conviction that gods may be physically immortal, and that this
13625-487: The result of misclassification leading to questions on whether there really are any ring species. The commonly used names for kinds of organisms are often ambiguous: "cat" could mean the domestic cat, Felis catus , or the cat family, Felidae . Another problem with common names is that they often vary from place to place, so that puma, cougar, catamount, panther, painter and mountain lion all mean Puma concolor in various parts of America, while "panther" may also mean
13750-586: The ring. Ring species thus present a difficulty for any species concept that relies on reproductive isolation. However, ring species are at best rare. Proposed examples include the herring gull – lesser black-backed gull complex around the North pole, the Ensatina eschscholtzii group of 19 populations of salamanders in America, and the greenish warbler in Asia, but many so-called ring species have turned out to be
13875-447: The risk of fatal trauma in any finite period is greater than zero. Mathematically, this is an aspect of achieving 'actuarial escape velocity' . Biological immortality is an absence of aging. Specifically it is the absence of a sustained increase in rate of mortality as a function of chronological age. A cell or organism that does not experience aging, or ceases to age at some point, is biologically immortal. Biologists have chosen
14000-407: The risk of the person to be declared dead and thus not be a legitimate owner of his or her property. After this point, the human body could be treated as an optional accessory and the program implementing the person could be transferred to any sufficiently powerful computer. Another possible mechanism for mind upload is to perform a detailed scan of an individual's original, organic brain and simulate
14125-508: The same species. This concept was narrowed in 2006 to a similarity of 98.7%. The average nucleotide identity (ANI) method quantifies genetic distance between entire genomes , using regions of about 10,000 base pairs . With enough data from genomes of one genus, algorithms can be used to categorize species, as for Pseudomonas avellanae in 2013, and for all sequenced bacteria and archaea since 2020. Observed ANI values among sequences appear to have an "ANI gap" at 85–95%, suggesting that
14250-529: The same species. When two species names are discovered to apply to the same species, the older species name is given priority and usually retained, and the newer name considered as a junior synonym, a process called synonymy . Dividing a taxon into multiple, often new, taxa is called splitting . Taxonomists are often referred to as "lumpers" or "splitters" by their colleagues, depending on their personal approach to recognising differences or commonalities between organisms. The circumscription of taxa, considered
14375-869: The solutions provided in research to any end providing such alternate theories at present that require unification. See also: DNA damage theory of aging Aubrey de Grey , a leading researcher in the field, defines aging as "a collection of cumulative changes to the molecular and cellular structure of an adult organism , which result in essential metabolic processes, but which also, once they progress far enough, increasingly disrupt metabolism, resulting in pathology and death." The current causes of aging in humans are cell loss (without replacement), DNA damage , oncogenic nuclear mutations and epimutations , cell senescence , mitochondrial mutations, lysosomal aggregates, extracellular aggregates, random extracellular cross-linking, immune system decline, and endocrine changes. Eliminating aging would require finding
14500-408: The soul was immortal and the souls of good people will be reincarnated and "pass into other bodies", while "the souls of the wicked will suffer eternal punishment." The Book of Jubilees seems to refer to the resurrection of the soul only, or to a more general idea of an immortal soul. Species A species ( pl. : species) is a population of organisms in which any two individuals of
14625-506: The species concept and making taxonomy unstable. Yet others defend this approach, considering "taxonomic inflation" pejorative and labelling the opposing view as "taxonomic conservatism"; claiming it is politically expedient to split species and recognise smaller populations at the species level, because this means they can more easily be included as endangered in the IUCN red list and can attract conservation legislation and funding. Unlike
14750-471: The subject of speculation and debate. In religious contexts, immortality is often stated to be one of the promises of divinities to human beings who perform virtue or follow divine law . Life extension technologies claim to be developing a path to complete rejuvenation . Cryonics holds out the hope that the dead can be revived in the future, following sufficient medical advancements. While, as shown with creatures such as hydra and Planarian worms, it
14875-516: The theory that we will be able to continually create biological or synthetic replacement parts to replace damaged or dying ones. Future advances in nanomedicine could give rise to life extension through the repair of many processes thought to be responsible for aging. K. Eric Drexler , one of the founders of nanotechnology , postulated cell repair devices, including ones operating within cells and using as yet hypothetical biological machines , in his 1986 book Engines of Creation . Raymond Kurzweil ,
15000-537: The time he gives us new hardware to run the software again for ourselves.' That gets to two things nicely: that the period after death (the Intermediate state ) is a period when we are in God's presence but not active in our own bodies, and also that the more important transformation will be when we are again embodied and administering Christ's kingdom ." This kingdom will consist of Heaven and Earth "joined together in
15125-480: The vast majority of speculation on immortality before the 21st century was regarding the nature of the afterlife. The viewpoints of Christianity , Islam , and Judaism regarding the concept of immortality diverge as each faith system encapsulates unique theological interpretations and doctrines on the enduring human nature soul or spirit . Christian theology holds that Adam and Eve lost physical immortality for themselves and all their descendants through
15250-540: The wild. It is difficult to define a species in a way that applies to all organisms. The debate about species concepts is called the species problem. The problem was recognised even in 1859, when Darwin wrote in On the Origin of Species : I was much struck how entirely vague and arbitrary is the distinction between species and varieties. He went on to write: No one definition has satisfied all naturalists; yet every naturalist knows vaguely what he means when he speaks of
15375-588: The word "immortal" to designate cells that are not limited by the Hayflick limit , where cells no longer divide because of DNA damage or shortened telomeres . The first and still most widely used immortal cell line is HeLa , developed from cells taken from the malignant cervical tumor of Henrietta Lacks without her consent in 1951. Prior to the 1961 work of Leonard Hayflick , there was the erroneous belief fostered by Alexis Carrel that all normal somatic cells are immortal. By preventing cells from reaching senescence one can achieve biological immortality; telomeres,
15500-410: Was not considered to be External, though sometimes referred to as one. His longevity is believed by Selene to be mostly due to technological means, although Apocalypse was already many centuries old before his first encounter with the technology he would later integrate himself with. Selene herself needs to maintain her supply of life force that she drains from human victims. More recently, however, it
15625-518: Was revealed that all Externals previously believed to have been killed by Selene or the Legacy Virus had in fact survived. The only way of effectively killing an External is by destroying their hearts, which consequently channels the life-force of the slain External into others, making them virtually all-powerful. Selene reveals she did not accomplish this deed herself because she could not handle
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