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28-720: (Redirected from MET ) [REDACTED] Look up met  or MET in Wiktionary, the free dictionary. Met , MET , The Met or The MET may refer to: Buildings [ edit ] Arts venues [ edit ] Metropolitan Museum of Art , or the Met, in New York City Manhattan Ensemble Theatre , or MET, in New York City Metropolitan Opera , or

56-977: A Nationally Recognized Testing Laboratory. Education [ edit ] Budapest Metropolitan University , formerly Budapest College of Communication and Business Manchester Metropolitan University , England, UK Michigan English Test , U.S./British language exam Muslim Educational Trust Meteorological agencies [ edit ] Met Éireann , Ireland Met Office , UK Policing [ edit ] Metropolitan Police Service of London, UK Science, technology, and mathematics [ edit ] Biology and medicine [ edit ] Mesenchymal–epithelial transition MET (gene) , encoding hepatocyte growth factor receptor Met, hypermethioninemia Microbial electrochemical technologies Chemical species [ edit ] Methionine , amino acid abbreviated as Met, or M Methylethyltryptamine , hallucinogen Patient-focused terms [ edit ] Metabolic equivalent of task ,

84-977: A Nationally Recognized Testing Laboratory. Education [ edit ] Budapest Metropolitan University , formerly Budapest College of Communication and Business Manchester Metropolitan University , England, UK Michigan English Test , U.S./British language exam Muslim Educational Trust Meteorological agencies [ edit ] Met Éireann , Ireland Met Office , UK Policing [ edit ] Metropolitan Police Service of London, UK Science, technology, and mathematics [ edit ] Biology and medicine [ edit ] Mesenchymal–epithelial transition MET (gene) , encoding hepatocyte growth factor receptor Met, hypermethioninemia Microbial electrochemical technologies Chemical species [ edit ] Methionine , amino acid abbreviated as Met, or M Methylethyltryptamine , hallucinogen Patient-focused terms [ edit ] Metabolic equivalent of task ,

112-609: A fictitious character in Mega Man (v-game) series Met 107 , a radio station in Bangkok Mind's Eye Theatre , a live-action role-playing game The Met: Policing London , BBC documentary series Business [ edit ] MetLife , insurance provider Metropolitan Stores , former Canadian chain Met Foods , American grocery store group MET Group , a Hungarian-Swiss energy company Eurofins MET Labs ,

140-440: A fictitious character in Mega Man (v-game) series Met 107 , a radio station in Bangkok Mind's Eye Theatre , a live-action role-playing game The Met: Policing London , BBC documentary series Business [ edit ] MetLife , insurance provider Metropolitan Stores , former Canadian chain Met Foods , American grocery store group MET Group , a Hungarian-Swiss energy company Eurofins MET Labs ,

168-649: A form of electric spacecraft propulsion Transport [ edit ] Nash Metropolitan automobile London Underground: Metropolitan line Metropolitan Railway , originating company Metropolitan Electric Tramways , tram company in London Metropolitan Transit Authority of Black Hawk County in Waterloo, Iowa, United States Modesto and Empire Traction Company , a shortline railroad Metropolitan Transit Authority (Victoria) , colloquially known as The Met ,

196-498: A form of electric spacecraft propulsion Transport [ edit ] Nash Metropolitan automobile London Underground: Metropolitan line Metropolitan Railway , originating company Metropolitan Electric Tramways , tram company in London Metropolitan Transit Authority of Black Hawk County in Waterloo, Iowa, United States Modesto and Empire Traction Company , a shortline railroad Metropolitan Transit Authority (Victoria) , colloquially known as The Met ,

224-443: Is an essential process in embryogenesis to gather mesenchymal-like cells into cohesive structures. Although the mechanism of MET during various organs morphogenesis is quite similar, each process has a unique signaling pathway to induce changes in gene expression profiles. One example of this, the most well described of the developmental METs, is kidney ontogenesis . The mammalian kidney is primarily formed by two early structures:

252-400: Is different from Wikidata All article disambiguation pages All disambiguation pages met [REDACTED] Look up met  or MET in Wiktionary, the free dictionary. Met , MET , The Met or The MET may refer to: Buildings [ edit ] Arts venues [ edit ] Metropolitan Museum of Art , or

280-479: Is different from Wikidata All article disambiguation pages All disambiguation pages Mesenchymal%E2%80%93epithelial transition Unlike epithelial cells – which are stationary and characterized by an apico-basal polarity with binding by a basal lamina , tight junctions , gap junctions , adherent junctions and expression of cell-cell adhesion markers such as E-cadherin , mesenchymal cells do not make mature cell-cell contacts, can invade through

308-758: The extracellular matrix , and express markers such as vimentin , fibronectin , N-cadherin , Twist , and Snail . MET plays also a critical role in metabolic switching and epigenetic modifications . In general epithelium-associated genes are upregulated and mesenchyme -associated genes are downregulated in the process of MET. During embryogenesis and early development, cells switch back and forth between different cellular phenotypes via MET and its reverse process, epithelial–mesenchymal transition (EMT). Developmental METs have been studied most extensively in embryogenesis during somitogenesis and nephrogenesis and carcinogenesis during metastasis , but it also occurs in cardiogenesis or foregut development. MET

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336-1271: The Met, in New York City Manhattan Ensemble Theatre , or MET, in New York City Metropolitan Opera , or the Met, in New York City Metropolitan Opera House (disambiguation) , various buildings The Met (arts centre) in Bury, Greater Manchester Manila Metropolitan Theater in Manila, Philippines Sports venues [ edit ] Met Center in Bloomington, Minnesota Met Park in Norfolk, Virginia MetLife Stadium in East Rutherford, New Jersey Metropolitan Stadium in Bloomington, Minnesota Other buildings [ edit ] Metropolitan Bible Church ("The MET"), Ottawa, Canada Metropolitan Building (Minneapolis) , until 1961 Metropolitan Miami (development) , Florida, US Metropolitan Theatre (Winnipeg) , Canada The Met (skyscraper) , Bangkok, Thailand Arts, entertainment, and media [ edit ] Met ,

364-779: The Met, in New York City Metropolitan Opera House (disambiguation) , various buildings The Met (arts centre) in Bury, Greater Manchester Manila Metropolitan Theater in Manila, Philippines Sports venues [ edit ] Met Center in Bloomington, Minnesota Met Park in Norfolk, Virginia MetLife Stadium in East Rutherford, New Jersey Metropolitan Stadium in Bloomington, Minnesota Other buildings [ edit ] Metropolitan Bible Church ("The MET"), Ottawa, Canada Metropolitan Building (Minneapolis) , until 1961 Metropolitan Miami (development) , Florida, US Metropolitan Theatre (Winnipeg) , Canada The Met (skyscraper) , Bangkok, Thailand Arts, entertainment, and media [ edit ] Met ,

392-437: The extensive studies of EMT in tumor metastasis, MET is believed to participate in the establishment and stabilization of distant metastases by allowing cancerous cells to regain epithelial properties and integrate into distant organs. Between these two states, cells occur in 'intermediate‐state', or so‐called partial EMT. In recent years, researchers have begun to investigate MET as one of many potential therapeutic targets in

420-475: The first 5 days post-OKSM induction. Addition of exogenous TGF-β1 , which blocks MET, decreased iPS reprogramming efficiency significantly. These findings are all consistent with previous observations that embryonic stem cells resemble epithelial cells and express E-cadherin. Recent studies have suggested that ectopic expression of Klf4 in iPS cell reprogramming may be specifically responsible for inducing E-cadherin expression by binding to promoter regions and

448-459: The former metropolitan public transport marketing agency for Melbourne, Australia Metropolitan West Side Elevated Railroad , one of the predecessors of the Chicago "L" system Other uses [ edit ] Mediterranean Editors and Translators association Middle European Time or Central European Time See also [ edit ] Mets (disambiguation) Topics referred to by

476-404: The former metropolitan public transport marketing agency for Melbourne, Australia Metropolitan West Side Elevated Railroad , one of the predecessors of the Chicago "L" system Other uses [ edit ] Mediterranean Editors and Translators association Middle European Time or Central European Time See also [ edit ] Mets (disambiguation) Topics referred to by

504-445: The initiation phase of reprogramming. Epithelial-associated genes such as E-cadherin/ Cdh1 , Cldns −3, −4, −7, −11, Occludin (Ocln), Epithelial cell adhesion molecule (Epcam), and Crumbs homolog 3 (Crb3), were all upregulated before Nanog , a key transcription factor in maintaining pluripotency , was turned on. Additionally, mesenchymal-associated genes such as Snail, Slug, Zeb −1, −2, and N-cadherin were downregulated within

532-400: The injured heart. Injured pericardium undergoes EMT and is transformed into adipocytes or myofibroblasts which induce arrhythmia and scars. MET than leads to the formation of vascular and epithelial progenitors that can differentiate into vasculogenic cells which lead to regeneration of heart injury. While relatively little is known about the role MET plays in cancer when compared to

560-415: The nephrogenic mesenchyme to condense around the bud and undergo MET to form the renal epithelium, which ultimately forms the nephron . Growth factors , integrins , cell adhesion molecules, and protooncogenes , such as c-ret , c-ros , and c-met , mediate the reciprocal induction in metanephrons and consequent MET. Another example of developmental MET occurs during somitogenesis . Vertebrate somites,

588-628: The physical intensity of an activity Motivational enhancement therapy Muscle energy technique , clinical neuromuscular protocol Space missions [ edit ] Mission Elapsed Time , a method of timekeeping during space missions Modular Equipment Transporter (Apollo program) , lunar handcart Other science and technology, and mathematics [ edit ] Met, the category of metric spaces having metric maps Met, unit of metabolic rate MET Matrix , materials, energy, and toxic emissions Missing transverse energy in particle physics Microwave electrothermal thruster ,

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616-628: The physical intensity of an activity Motivational enhancement therapy Muscle energy technique , clinical neuromuscular protocol Space missions [ edit ] Mission Elapsed Time , a method of timekeeping during space missions Modular Equipment Transporter (Apollo program) , lunar handcart Other science and technology, and mathematics [ edit ] Met, the category of metric spaces having metric maps Met, unit of metabolic rate MET Matrix , materials, energy, and toxic emissions Missing transverse energy in particle physics Microwave electrothermal thruster ,

644-426: The precursors of axial bones and trunk skeletal muscles, are formed by the maturation of the presomitic mesoderm (PSM). The PSM, which is composed of mesenchymal cells, undergoes segmentation by delineating somite boundaries (see somitogenesis for more details). Each somite is encapsulated by an epithelium, formerly mesenchymal cells that had undergone MET. Two Rho family GTPases – Cdc42 and Rac1 – as well as

672-606: The prevention of metastases. This approach to preventing metastasis is known as differentiation-based therapy or differentiation therapy and it can be used for development of new anti-cancer therapeutic strategies. A number of different cellular processes must take place in order for somatic cells to undergo reprogramming into induced pluripotent stem cells (iPS cells). iPS cell reprogramming, also known as somatic cell reprogramming, can be achieved by ectopic expression of Oct4 , Klf4 , Sox2 , and c-Myc (OKSM). Upon induction, mouse fibroblasts must undergo MET to successfully begin

700-403: The same term [REDACTED] This disambiguation page lists articles associated with the title Met . If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=Met&oldid=1259913787 " Category : Disambiguation pages Hidden categories: Short description

728-403: The same term [REDACTED] This disambiguation page lists articles associated with the title Met . If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=Met&oldid=1259913787 " Category : Disambiguation pages Hidden categories: Short description

756-411: The transcription factor Paraxis are required for chick somitic MET. Development of heart is involved in several rounds of EMT and MET. While development splanchnopleure undergo EMT and produce endothelial progenitors, these then form the endocardium through MET. Pericardium is formed by sinus venosus mesenchymal cells that undergo MET. Quite similar processes occur also while regeneration in

784-478: The ureteric bud and the nephrogenic mesenchyme, which form the collecting duct and nephrons respectively (see kidney development for more details). During kidney ontogenesis, a reciprocal induction of the ureteric bud epithelium and nephrogenic mesenchyme occurs. As the ureteric bud grows out of the Wolffian duct, the nephrogenic mesenchyme induces the ureteric bud to branch. Concurrently, the ureteric bud induces

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