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Molecular Sciences Institute

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The Molecular Sciences Institute ( MSI ), now located in Milpitas, California was founded in Berkeley, California by Sydney Brenner in 1996. Its mission was to operate as an independent non-profit research laboratory that combined genomic experimentation with computer modeling . Current efforts include co-curricular STEAM programming for youth and quick launch strategies for products/technologies addressing global health. In the last few years, MSI has integrated into the startup community through providing research and development facilities and mentorship.

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61-660: This organization has been supported by federal grants from the National Institutes of Health (NIH), the Defense Advanced Research Projects Agency (DARPA) and other funds provided by foundations and corporations. This article about a biology organization is a stub . You can help Misplaced Pages by expanding it . Federal grant In the United States , federal grants are economic aid issued by

122-472: A 1,000-stall public parking garage and assist with cleanup of the land, which had been used as a Metro Transit bus base. The two-building headquarters campus opened in June 2011 at a cost of $ 500 million and was designed by NBBJ . The design was awarded LEED Platinum status for its environmentally-friendly features, including a living roof , a rainwater retention pool, and a rooftop solar array . In 2010,

183-433: A back-up plan in the event that its co-chairs could not work together due to their recent divorce. The deal gave Bill and Melinda a two-year trial, after which Melinda could resign from the organization as well as receiving personal resources from her ex-husband for her own charity work. On May 13, 2024, Melinda Gates resigned as co-chair of the foundation, to be effective June 7, 2024. The foundation will then be renamed to

244-1437: A combination of federal and state grants, private donations, and institutional funds. Many universities and research institutions offer grants to support academic research projects. These grants are often funded by federal agencies, private foundations, and corporate sponsors. Examples include research grants provided by the National Science Foundation (NSF) and the National Institutes of Health (NIH). Educational institutions provide scholarships and fellowships to support students’ educational pursuits. These grants can be merit-based, need-based, or specific to certain fields of study. They are funded through endowments, private donations, and institutional funds. Award information in grants generally includes: Eligibility information includes: Federal and state grants frequently receive criticism due to what are perceived to be excessive regulations and not include opportunities for small business , as well as for often giving more money per person to smaller states regardless of population or need. These criticisms include problems of overlap, duplication, excessive categorization, insufficient information, varying requirements, arbitrary federal decision-making, and grantsmanship (a funding bias toward entities most familiar with how to exploit

305-509: A day-to-day role with Microsoft , effective July 31, 2008, to allow him to devote more time to working with the foundation. The first CEO of the foundation, until she stepped down in 2008, was Patty Stonesifer . In 2005, Bill Gates and Melinda French Gates , along with the Irish rock musician Bono , were named by Time as Persons of the Year 2005 for their outstanding charitable work. In

366-546: A full-fledged program under the Global Development Division in early 2010. The foundation has since 2005 undertaken a wide range of efforts in the WASH sector involving research, experimentation, reflection, advocacy , and field implementation. In 2009, the foundation decided to refocus its WASH effort mainly on sustainable sanitation services for the poor, using non-piped sanitation services (i.e. without

427-508: A human rights organization based in Washington, D.C., US to work in the area of sex trafficking . The official announcement explained that the grant would allow the IJM to "create a replicable model for combating sex trafficking and slavery" that would involve the opening of an office in a region with high rates of sex trafficking, following research. The office was opened for three years for

488-418: A hygienic, stand-alone toilet. This challenge is being complemented by another investment program to develop new technologies for improved pit latrine emptying (called by the foundation the "Omni-Ingestor" ) and fecal sludge processing (called " Omni-Processor "). The aim of the "Omni Processor" is to convert excreta (for example fecal sludge ) into beneficial products such as energy and soil nutrients with

549-458: A sustainable, inclusive agricultural transformation—one that creates economic opportunity, respects limits on natural resources, and gives everyone equal access to affordable, nutritious food". The foundation's agricultural investments include: The Water, Sanitation and Hygiene ( WASH ) program of the Bill & Melinda Gates Foundation was launched in mid-2005 as a "Learning Initiative", and became

610-640: A thing of value to the State or local government or other recipient to carry out a public purpose of support or stimulation authorized by a law of the United States instead of acquiring (by purchase, lease, or barter) property or services for the direct benefit or use of the United States Government; and 2) substantial involvement is not expected between the executive agency and the State, local government, or other recipient when carrying out

671-701: A wide range of community initiatives. Examples include the Cleveland Foundation and the Silicon Valley Community Foundation. In addition to corporate foundations, many corporations provide grants directly through their corporate social responsibility (CSR) programs. These grants are often used to support community development, environmental sustainability , education, and employee volunteerism. Corporations may offer direct grants to nonprofit organizations, schools, and other entities. These grants are typically aligned with

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732-562: Is intended to lower administrative costs over the years of the Foundation Trust's life and ensure that the Foundation Trust does not fall into a situation where the vast majority of its expenditures are on administrative costs, including salaries, with only token amounts contributed to charitable causes. To maintain its status as a charitable foundation , the Bill & Melinda Gates Foundation must donate funds equal to at least five percent of its assets each year. As of April 2014,

793-440: Is lowest in those regions. Their grant-making focus has been since 2011 on sanitation science and technology ("transformative technologies"), delivery models at scale, urban sanitation markets, building demand for sanitation, measurement and evaluation as well as policy, advocacy and communications. In mid-2011, the foundation stated that they had committed more than $ 265 million to the water, sanitation, and hygiene sector over

854-580: Is tasked to monitor progress towards the Millennium Development Goal (MDG) relating to drinking water and sanitation. About one billion people have no sanitation facility whatsoever and continue to defecate in gutters, behind bushes or in open water bodies, with no dignity or privacy. This is called open defecation and it poses significant health risks. India is the country with the highest number of people practicing open defecation, with around 157 million people or approximately 11% of

915-548: The Gates Foundation with Bill Gates as the sole chairman. On June 25, 2006, Warren Buffett pledged to give the foundation approximately 10 million Berkshire Hathaway Class B shares (then valued at $ 3,071 each, before a 50–1 stock split in 2010) spread over multiple years through annual contributions, with the first year's donation of 500,000 shares being worth approximately $ 1.5 billion. Buffett set conditions so that these contributions do not simply increase

976-577: The International Aid Transparency Initiative . In December 2013 Susan Desmond-Hellmann , president of product development for Genentech before its acquisition by Roche Pharmaceuticals , was announced as BMGF's next CEO. She replaced Jeff Raikes on 1 May 2014. In February 2014 Hillary Clinton launched a partnership between the foundation and the Clinton Foundation to gather and study data on

1037-566: The U.S. Securities and Exchange Commission , the trust owned the following investments (almost 202 million shares) worth a total of over $ 45 billion: Christopher Elias leads the foundation's efforts to combat extreme poverty through grants as president of the Global Development Program. In March 2006, the foundation announced a $ 5 million grant for the International Justice Mission (IJM),

1098-641: The United States government out of the general federal revenue. A federal grant is an award of financial assistance from a federal agency to a recipient to carry out a public purpose of support or stimulation authorized by a law of the United States. Grants are federal assistance to individuals, benefits or entitlements . A grant is not used to acquire property or services for the federal government's direct benefit. Grants may also be issued by private non-profit organizations such as foundations , not-for-profit corporations or charitable trusts which are all collectively referred to as charities . Outside

1159-901: The United Way and the American Heart Association, provide grants to support programs and services that align with their mission. These grants often focus on areas such as health, education, social services, and disaster relief . Philanthropic networks and collaboratives, such as Grantmakers for Education and the Environmental Grantmakers Association, consist of multiple foundations and grantmakers that work together to fund projects and initiatives within specific focus areas. Educational institutions, including colleges and universities, often provide grants to support research, scholarships , and educational programs. These grants are funded through

1220-519: The benefactor . Federal grants are defined and governed by the Federal Grant and Cooperative Agreement Act of 1977 , as incorporated in Title 31 Section 6304 of the U.S. Code . A Federal grant is a: "...legal instrument reflecting the relationship between the United States Government and a State, a local government, or other entity when 1) the principal purpose of the relationship is to transfer

1281-578: The BMGF was acting as a fund aggregator for wealthy donors: the name recognition associated with BMGF caused more money to be placed than an anonymous control. This was particularly useful during the COVID-19 pandemic because the BMGF already knew which organizations were working in the field and able to receive funds. When former President Trump threatened to defund the WHO in summer 2020 over concerns that it

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1342-738: The BMGF's committed funding as recorded in their International Aid Transparency Initiative (IATI) publications. The BMGF announced in October 2013 that it would join the IATI. The IATI publications only include a subset of BMGF grants (mainly excluding grants to developed countries), and contain few grants before 2009 (which are entirely excluded from the table). The BMGF states on the IATI Registry site that "reporting starts from 2009 and excludes grants related to our US programs and grants that if published could harm our employees, grantees, partners, or

1403-424: The Bill & Melinda Gates Foundation would not receive any more money after he died. While this does not prevent him from making any further donations while he is still alive, the recipients of his fortune upon his death will be decided unanimously by his three children. In October 2006, the Bill & Melinda Gates Foundation was split into two entities: the Bill & Melinda Gates Foundation Trust, which manages

1464-498: The Bill & Melinda Gates Foundation. In the 2006 announcement, it was reiterated that Warren Buffett "... has stipulated that the proceeds from the Berkshire Hathaway shares he still owns at death are to be used for philanthropic purposes within 10 years after his estate has been settled". The plan to close the Foundation Trust is in contrast to most large charitable foundations that have no set closure date. This

1525-535: The Toilet Challenge" is focused on "reinventing the flush toilet ". The aim was to create a toilet that not only removes pathogens from human excreta , but also recovers resources such as energy, clean water, and nutrients (a concept also known as reuse of excreta ). It should operate " off-the-grid " without connections to water, sewer, or electrical networks. Finally, it should cost less than 5 cents per user per day. High-tech toilets for tackling

1586-496: The Toilet Challenge", more than a dozen research teams, mainly at universities in the U.S., Europe, India, China, and South Africa, have received grants to develop innovative on-site and off-site waste treatment solutions for the urban poor. The grants were in the order of $ 400,000 for their first phase, followed by typically $ 1 million – 3 million for their second phase; many of them investigated resource recovery or processing technologies for excreta or fecal sludge . The "Reinvent

1647-411: The United States grants, subventions or subsidies are used to in similar fashion by government or private charities to subsidize programs and projects that fit within the funding criteria of the grant-giving entity or donor. Grants can be unrestricted, to be used by the recipient in any fashion within the perimeter of the recipient organization's activities or they may be restricted to a specific purpose by

1708-1507: The United States which applies to federal procurement policy is also applied to the use of federal grants. For charitable grants and funds for schools and organizations see: Grant writing and Grants . There are over 900 grant programs offered by the 26 federal grant-making agencies. These programs fall into 20 categories: State and local governments also provide grants to support various projects and initiatives within their jurisdictions. These grants often focus on areas such as economic development, education, public safety, healthcare , and infrastructure. State grants are financial awards provided by individual states to support projects and programs that benefit residents. These grants can be used for purposes such as education, environmental conservation, public health, and community development. Each state has its own agencies and programs that administer these grants. Local government grants are offered by counties, cities, and municipalities to support local initiatives. These grants often target community-specific needs, such as housing, transportation, public safety, and cultural programs. Local governments may also pass through federal and state grant funds to local organizations. Private foundations are nonprofit organizations that provide grants to support various causes and initiatives. These foundations are typically funded by individuals, families, or corporations and have specific focus areas, such as education, health, social services, arts, and

1769-659: The WHO. It was revealed after the fact that the BMGF had contributed US$ 1.553 billion to the GAVI over the five years 2016 to 2020. The BMGF was the number two ranked contributor. At the Global Vaccine Summit in June 2020, the BMGF pledged $ 1.6 billion (or just under 20% of the total) for the subsequent five years. In May 2022, the Gates Foundation announced the commitment of $ 125 million to aid in ending

1830-492: The activity contemplated in the agreement." When an awarding agency expects to be substantially involved in a project (beyond routine monitoring and technical assistance), the law requires use of a cooperative agreement instead. When the government is procuring goods or services for its own direct benefit, and not for a broader public purpose, the law requires use of a federal contract. The preference for use of goods, products, and materials produced in, and services offered in,

1891-592: The acute phase of the COVID-19 pandemic and to aid in preparing for future pandemics. In total since the start of the COVID-19 pandemic the Gates Foundation has committed more than $ 2 billion to COVID-19 response efforts. In 2015, it co-funded a community known as Agriculture, Nutrition and Health Academy in partnership with the United Kingdom Aid from the UK government. In July 2021, the foundation agreed on

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1952-514: The beneficiaries of our work". The following table lists the top receiving organizations to which the Bill & Melinda Gates Foundation has committed funding, between 2009 and 2015. The table again only includes grants recorded in the Gates Foundation's IATI publications. According to the OECD , the Bill & Melinda Gates Foundation provided US$ 4.1 billion for development in 2019. The foundation explains on its website that its trustees divided

2013-787: The case of the Gates, the work referenced was that of BMGF. On 12 May 2008 it was announced that Jeff Raikes would replace Stonesifer as the CEO of the BMGF. The foundation announced in January 2005 that it would build its headquarters campus on 12 acres (4.9 ha) adjacent to the Seattle Center in Downtown Seattle . The foundation purchased the property for $ 50.4 million from the Seattle city government, who would help build

2074-661: The company’s CSR goals and business priorities. For example, a technology company might provide grants to support STEM education programs. Some corporations provide in-kind donations instead of or in addition to monetary grants. In-kind donations can include products, services, technology, and expertise that support the recipient organization's operations and programs. Many nonprofit organizations provide grants to support specific causes and initiatives. These organizations raise funds from various sources, including private donors, foundations, and government grants, and redistribute them through grant programs. Nonprofit grantmakers, such as

2135-456: The endowment assets and the Bill & Melinda Gates Foundation, which "... conducts all operations and grantmaking work, and it is the entity from which all grants are made". Also announced was the decision to spend all of the foundation's resources within 50 years after Bill's and Melinda's deaths. This was later lowered to within 20 years of their death. This would close the Bill & Melinda Gates Foundation Trust and effectively end

2196-703: The environment. Independent foundations, also known as private foundations, are established by individuals or families and operate independently of government control. Examples include the Bill & Melinda Gates Foundation and the Ford Foundation. These foundations often have substantial endowments and provide grants to nonprofit organizations, educational institutions, and other entities that align with their mission and goals. Corporate foundations are philanthropic arms of corporations that provide grants to support charitable activities. These foundations are funded by

2257-645: The following purposes: "conducting undercover investigations, training law enforcement, rescuing victims, ensuring appropriate aftercare, and seeking perpetrator accountability". The IJM used the grant money to found "Project Lantern" and established an office in the Philippines city of Cebu . In 2010, the results of the project were published, in which the IJM stated that Project Lantern had led to "an increase in law enforcement activity in sex trafficking cases, an increase in commitment to resolving sex trafficking cases among law enforcement officers trained through

2318-408: The foundation and the way it seeks to apply business techniques to giving makes it one of the leaders in venture philanthropy , though the foundation itself notes that the philanthropic role has limitations. In 2007, its founders were ranked as the second most generous philanthropists in the U.S., behind Warren Buffett. As of 2018, Bill Gates and Melinda French Gates had donated around $ 36 billion to

2379-549: The foundation as necessary to achieve the foundation's charitable goals"—it holds the assets of Bill and Melinda Gates, who are the sole trustees, and receives contributions from Buffett. The foundation posts its audited financial statements and 990-PF forms on the "Financials" section of its website as they become available. At the end of 2023, the foundation registered a cash sum of $ 194,354,000, and net assets of $ 71,290,995,000 (of which 99.84% are unrestricted). As of 30 September 2024 , according to documents filed with

2440-410: The foundation is organized into four program areas under chief executive officer Susan Desmond-Hellmann, who "sets strategic priorities, monitors results, and facilitates relationships with key partners": The foundation maintains an online database of grants. In November 2014, the Gates Foundation announced that they were adopting an open access (OA) policy for publications and data , "to enable

2501-482: The foundation two years to abide by the third requirement." The Gates Foundation received 5% (500,000) of the shares in July 2006 and will receive 5% of the remaining earmarked shares in the July of each following year (475,000 in 2007, 451,250 in 2008). In July 2018, Buffet announced another donation of his company's Class B stock, this time worth $ 2 billion, to the Gates Foundation. In June 2024, Buffett clarified

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2562-503: The foundation's endowment, but effectively work as a matching contribution, doubling the foundation's annual giving. Bloomberg News noted, "Buffett's gift came with three conditions for the Bill & Melinda Gates Foundation: Bill or Melinda Gates must be alive and active in its administration; it must continue to qualify as a charity; and each year it must give away an amount equal to the previous year's Berkshire gift, plus an additional amount equal to 5 percent of net assets . Buffett gave

2623-603: The foundation's founders started the Commission on Education of Health Professionals for the 21st Century, entitled "Transforming education to strengthen health systems in an interdependent world." A 2011 survey of grantees found that many believed the foundation did not make its goals and strategies clear and sometimes did not understand those of the grantees; that the foundation's decision-making and grantmaking procedures were too opaque; and that its communications could be more consistent and responsive. The foundation's response

2684-630: The foundation. Since its founding, the foundation has endowed and supported a broad range of social, health, and education developments, including the establishment of the Gates Cambridge Scholarships at Cambridge University . In 1994, the foundation was formed as the William H. Gates Foundation. In May 2002, the foundation purchased stocks in pharmaceutical companies Johnson & Johnson , Merck , and Pfizer . On June 15, 2006, Gates announced his plans to transition out of

2745-399: The growing public health problem of human waste are gaining increasing attention, but this focus on a "technology fix" has also been criticized by many in the sector. However, low-tech solutions may be more practical in poor countries, and research is also funded by the foundation for such toilets. The Reinvent the Toilet Challenge is a long-term research and development effort to develop

2806-412: The mainstream media. It was complemented by a program called "Grand Challenges Explorations" (2011 to 2013 with some follow-up grants reaching until 2015) which involved grants of $ 100,000 each in the first round. Both funding schemes explicitly excluded project ideas that relied on centralized sewerage systems or are not compatible with development country contexts. Since the launch of the "Reinvent

2867-437: The organization into two entities: the Bill & Melinda Gates Foundation and the Bill & Melinda Gates Foundation Trust. The foundation section, based in Seattle, US, "focuses on improving health and alleviating extreme poverty", and its trustees are currently Bill and Melinda Gates; Warren Buffett announced his resignation as a trustee on June 23, 2021. The trust section manages "the investment assets and transfer proceeds to

2928-557: The parent company and focus on areas that align with the corporation’s values and business interests. Examples include the Coca-Cola Foundation and the Walmart Foundation . Community foundations are public charities that provide grants to support local community needs. These foundations pool donations from multiple sources, including individuals, families, and businesses, to create endowment funds that support

2989-552: The past five years, i.e. since about 2006. For the time period of about 2008 to mid-2015, all grants awarded to water, sanitation, and hygiene projects totaled a value of around $ 650 million, according to the publicly available grant database. Improved sanitation in the developing world is a global need, but a neglected priority, as shown by the data collected by the Joint Monitoring Programme for Water Supply and Sanitation (JMP) of UNICEF and WHO. This program

3050-671: The progress of women and girls around the world since the 1995 United Nations Fourth World Conference on Women in Beijing. This is called "No Ceilings: The Full Participation Project". In October 2019, the BMGF partnered with the World Economic Forum to host the tabletop exercise called Event 201 in New York City . In February 2020, BMGF CEO Desmond-Hellmann was replaced "for health and family reasons" by Mark Suzman. As early as 2012, there were reports that

3111-440: The project, and an increase in services – like shelter, counseling, and career training – provided to trafficking survivors". At the time that the results were released, the IJM was exploring opportunities to replicate the model in other regions. In October 2000, William Gates established the Gates Cambridge Scholarships which allow students and scholars from the U.S. and around the world to study at Cambridge University , one of

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3172-538: The same initiative launched in 2016 by Wellcome Trust in their Wellcome Open Research policy launched in partnership with F1000 Research . The Gates Foundation supported Our World in Data , one of the world's largest open-access publications. Bill Gates called the publication his "favorite website". In 2024, the Gates Foundation announced a "preprint-centric" open access policy, and their intention to stop paying article-processing charges. The following table lists

3233-445: The scholarship, making it one of the largest and best-endowed scholarships in the world. The Gates Cambridge Scholarship accepts less than 0.3% of applicants and remains extremely competitive. Each year, approximately 100 new graduate students from around the world receive funding to study at Cambridge. The BMGF's goal for agricultural development is "to support farmers and governments in sub-Saharan Africa and South Asia that are seeking

3294-592: The system, rather than to those most in need). Research also suggests that federal grants are often allocated politically, with more money going to areas represented by the political party commanding a majority in Congress or that controls the presidency. Bill %26 Melinda Gates Foundation The Bill & Melinda Gates Foundation ( BMGF ) is an American private foundation founded by Bill Gates and Melinda French Gates . Based in Seattle , Washington, it

3355-629: The top universities in the world. The Gates Cambridge Scholarship has often been compared to the Rhodes Scholarship , given its similarly international scope and substantial endowment. In 2000, the Gates Foundation endowed the scholarship trust with $ 210 million to help outstanding graduate students outside of the United Kingdom study at the University of Cambridge . The Gates Foundation has continued to contribute funds to expand

3416-557: The total population in 2022, although the situation has improved significantly since then. The foundation has been funding many sanitation research and demonstration projects in India since about 2011. In 2011, the foundation launched a program called "Reinvent the Toilet Challenge" with the aim to promote the development of innovations in toilet design to benefit the 2.5 billion people that do not have access to safe and effective sanitation. This program has generated significant interest of

3477-400: The unrestricted access and reuse of all peer-reviewed published research funded by the foundation, including any underlying data sets". Its terms have been called the most stringent among similar OA policies. As of January 1, 2015, their Open Access policy is effective for all new agreements. In March 2017, it was confirmed that the open access policy, Gates Open Research , would be based on

3538-526: The use of sewers ), and less on water supply . This was because the sanitation sector was generally receiving less attention from other donors and from governments, and because the foundation believed it had the potential to make a real difference through strategic investments. In mid-2011, the foundation announced in its new "Water, Sanitation, Hygiene Strategy Overview" that its funding now focuses primarily on sanitation, particularly in sub-Saharan Africa and South Asia, because access to improved sanitation

3599-577: Was launched in 2000 and is reported to be the third largest charitable foundation in the world , holding $ 69 billion in assets as of 2020. The primary stated goals of the foundation are to enhance healthcare and reduce extreme poverty across the world, and to expand educational opportunities and access to information technology in the U.S. Key individuals of the foundation include Warren Buffett , chief executive officer Mark Suzman, and Michael Larson . The BMGF had an endowment of approximately $ 75.2 billion as of December 31, 2023 . The scale of

3660-412: Was to improve the clarity of its explanations, make "orientation calls" to grantees upon awarding grants, tell grantees who their foundation contact is, give timely feedback when they receive a grantee report, and establish a way for grantees to provide anonymous or attributed feedback to the foundation. The foundation also launched a podcast series. In October 2013, the BMGF announced that it would join

3721-491: Was too "deferential" to the Chinese Communist Party , because the BMGF constituted at that time the second-ranked contributor to the WHO, concerns were raised in the charity and academic sector that the BMGF might conceivably bias the WHO in the pursuit of its ideology. In the most timely accounting period, the BMGF provided 45% of the WHO's NGO funds, or in other words 12% of the total operating expenditure of

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