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Medicines Discovery Catapult

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The Medicines Discovery Catapult ( MDC ) is the United Kingdom's catapult centre for medicine research and innovation, headquartered at Alderley Park in Cheshire .

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40-859: The intention to form the company was announced by the Chancellor on 13 July 2015 with funding of £5m, on a visit to Cheshire. It would be part of the Northern Powerhouse initiative. The Medicines Technologies Catapult was established in December 2015, funded by a £10m grant from Innovate UK and based at the Alderley Park science park in Cheshire. On 1 March 2016 its name changed to the Medicines Discovery Catapult. Further funding of approximately £10m per year

80-534: A concept and who coined the phrase itself in a keynote speech in June 2014. Its vice-chairs are Lord Jim O'Neill , one of the original architects of the Northern Powerhouse vision, and leading industrialist Professor Juergen Maier CBE, former CEO of Siemens UK. NPP is business-led and fosters collaboration between places and national government, working together on evidence-based objectives which can make

120-409: A generational leadership transition at the subsequent party congress. The powers and roles of the general secretary are vaguely defined, with no term limits or written rules for selecting a successor. However, as China is a one-party state , the general secretary holds ultimate power and authority over state and government, and is usually considered the " paramount leader " of China. According to

160-515: A new £110 million theatre named The Factory (named after Factory Records ). In April 2016 the Government launched The Great Exhibition of the North , investing "£5 Million towards the exhibition with an additional £15 million into a legacy fund to attract further cultural investment in the Northern Powerhouse". In March 2017, a delegation of 30 digital and technology leaders from

200-478: A number of achievements: there were now five new "metro mayors" and a regional transport body - Transport for the North; employment had increased 7%, compared to the UK average of just over 6%; there were 34,520 more professional, scientific and technical jobs in 2019 compared with 2014 plus a further 54,523 jobs in manufacturing; there was "marginally" higher economic growth in the north than the national average (0.1% above

240-543: A number of reports into its key priorities, including Educating the North and the 'HS2 and the economy of the North'. NPP has campaigned extensively for the full delivery of both HS2 and Northern Powerhouse Rail, securing a promise from Prime Minister Boris Johnson in February 2020 that "both are needed, and both will be built." It has also called for more powers to be devolved to Metro Mayors, including in skills, transport and health. The Northern Powerhouse Partner Programme

280-403: A series of devolution deals signed between 2014 and 2020. Metro Mayors oversee a number of local authority areas across a ‘combined authority’ (usually with a city at its core), creating a new tier of government between Westminster and local councils. In February 2017 Goole band Sandra's Wedding released an album named Northern Powerhouse , inspired by the policies and political implications of

320-500: A stated capacity of 80,000 test samples per day. Dr Robin Brown has been the company's chairman since July 2018; he has a PhD in molecular biology and has worked in venture capital at Advent Healthcare . The company has no shareholders. Previously, Professor Graham Boulnois was chairman from January 2016; he was head of research from 1992 to 2000 at Zeneca Pharmaceuticals in Cheshire, and Professor of Microbiology from 1984 to 1992 at

360-732: A thread running throughout Government policy, not an idea that waxes and wanes according to political circumstances,” he said. General Secretary of the Chinese Communist Party The general secretary of the Central Committee of the Chinese Communist Party ( Chinese : 中国共产党中央委员会总书记 ; pinyin : Zhōngguó Gòngchǎndǎng Zhōngyāng Wěiyuánhuì Zǒngshūjì ) is the leader of the Chinese Communist Party (CCP),

400-517: Is Xi Jinping , who took office on 15 November 2012 and was re-elected twice on 25 October 2017 and 23 October 2022. The last person to rule the country for more than two terms was Mao Zedong , who served as Chairman of the CCP Central Committee from 1943 until his death in 1976. The post was established by the 12th Central Committee in 1982, replacing the post of Chairman of the Chinese Communist Party. Since its revival in 1982,

440-489: Is a government initiative made up of businesses from across the North, from international organisations with a Northern presence to SMEs and from a variety of sectors. The aim of the programme is to showcase activity, from apprenticeship opportunities to clean growth initiatives, highlighting business success across the Northern Powerhouse. The first Metro Mayors were elected in 2017 as part of then-Chancellor George Osborne’s plan to decentralise power away from Whitehall through

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480-594: Is also the head of the Secretariat , and sets the agenda of Central Committee, Politburo and PSC meetings. Since the 1990s, the holder of the post has been, except for transitional periods, the president of China , making the holder the head of state, and the chairman of the Central Military Commission (CMC), the supreme commander of the People's Liberation Army (PLA). As the leader of

520-720: The Constitution of the Chinese Communist Party , the general secretary serves as an ex officio member of the Politburo Standing Committee. According to regulations of the CCP, the general secretary is responsible for convening the meetings of the Politburo and the Politburo Standing Committee. The general secretary additionally presides over the work of the Secretariat. The general secretary also sets

560-495: The Northern and TransPennine Express franchises. These franchises will come with £1.2 billion of investment in more than 500 brand-new carriages, 2,000 extra services a week, free wi-fi on trains and at stations. The outdated diesel powered Pacer trains will also be removed from the network in 2020. The co-management of the franchises will be undertaken by Transport for the North and Government from April 2018, transferring

600-634: The University of Leicester . This article about an organisation in the United Kingdom is a stub . You can help Misplaced Pages by expanding it . This article about medicinal chemistry is a stub . You can help Misplaced Pages by expanding it . Northern Powerhouse The Northern Powerhouse was a proposal to boost economic growth in the North of England by the 2010–2015 coalition government and 2015–2016 Conservative government in

640-688: The sole ruling party of the People's Republic of China (PRC). Since 1989, the CCP general secretary has been the paramount leader of the PRC. According to the CCP constitution , the general secretary is elected during a plenary session of the Central Committee . The general secretary serves as an ex officio member of the Politburo Standing Committee (PSC), China's de facto top decision-making body. The general secretary

680-541: The Chinese Communist Party Xi Jinping 's visit to the UK , Prime Minister David Cameron announced that the Northern Powerhouse proposal had "Chinese backing". Under the government of Theresa May who became Prime Minister in July 2016, it was alleged that the focus on the North was to be downgraded into a nationwide agenda for boosting productivity outside the south-east. However, this

720-434: The North of England visited San Francisco, home of tech companies including Facebook, Apple and Uber , on a Northern Powerhouse trade mission. The trip was coordinated by MC2, a Northern Powerhouse partner, and the delegation was led by Professor Adam Beaumont, founder and CEO of telecoms operator aql . The flight marked the first ever direct service from the North to San Francisco and the only such route outside of London in

760-527: The North of England. In June 2015, the government suspended electrification of the Midland Main Line from London to Sheffield , and the TransPennine route between Manchester and Leeds amid spiraling costs and missed targets just weeks after winning the 2015 election . In December 2015, the Government awarded the two rail franchises in the North of England from April 2016 onwards,

800-547: The North of England. The proposal involved improvement to transport links, investment in science and innovation, and devolution of powers in City Deals . Former MP for Stockton South James Wharton was appointed as minister responsible for the proposal in May 2015. A 2018 investigation by The Guardian indicated he rarely left London to visit the northern areas, however. In October 2015, during General Secretary of

840-476: The Northern Powerhouse was "a vague and problematic concept". His assessment was that it had attracted new resources but was "geographically fuzzy with insufficient funding to achieve its unclear aims". In 2019, Andy Burnham, mayor of Greater Manchester, told the BBC the project was at risk of "fizzling out". The think tank IPPR North noted both positive and negative results for the Northern Powerhouse. IPPR pointed out

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880-566: The PMC would close, with most of its functions transferred to the MDC. The Leeds site is now the Leeds Centre for Personalised Medicine and Health. A not-for-profit company, the MDC works with a range of UK innovators to advance projects and products towards clinical impact. In 2019, the company stated that it worked in four sectors: In the same year, the number of staff increased from 40 to 75, and

920-485: The UK as a whole). However, there had also been negative changes: spending had risen by more than twice as much per person in London as in the north; late trains on northern franchises have more than doubled over the lifetime of the Northern Powerhouse; 200,000 more children were living in poverty; 150,000 more people were in jobs paying less than the living wage; and while there had been £3.6 billion in public spending cuts in

960-476: The UK from April 2018. Working with central government and national transport bodies, TfN will develop and deliver strategic transport infrastructure across the North of England . Proposed transport improvements include Northern Powerhouse Rail (otherwise known as High Speed 3) and the ongoing work of the Northern Hub to remove a railway bottleneck around Manchester and provide faster connections across

1000-482: The UK. The trip resulted in a new partnership between aql and CircleLoop, a smart online phone system provider. Links were also forged with incubation experts, including Rocketspace. The Northern Powerhouse Partnership (NPP) was launched in September 2016 as the leading voice of business and civic leaders across the North. NPP is chaired by the former Chancellor George Osborne who backed the Northern Powerhouse as

1040-619: The United Kingdom, particularly in the " Core Cities " of Hull , Manchester , Liverpool , Leeds , Sheffield and Newcastle . The proposal was based on the benefits of agglomeration and aimed to reposition the British economy away from London and the South East, where most of the UK's wealth was historically concentrated. The spatial footprint of the Northern Powerhouse was defined as the 11 local enterprise partnership areas of

1080-618: The biggest impact to deliver sustainable growth and to improve quality of life. Its membership is made up of the North’s leading businesses, including Bruntwood, TalkTalk, Co-op, Mace, Arup, Arcadis, Barclays, HSBC, Drax, Virgin Money and Sellafield. The first Northern Powerhouse Partnership (NPP) report was released in January 2017. The report outlined a plan to grow the region's economy by £100bn and create 850,000 jobs. Since then, NPP has published

1120-463: The company reported that its income comprised £8.5m from Innovate UK and £152,000 from collaborative research and development. After charging £7.1m to administrative expenses, the company reported a loss for the year of £16,000. In 2020, the company was given the task of setting up one of the first PCR analysis centres for COVID-19 tests – known as Lighthouse labs – elsewhere at the Alderley Park site. By 2021, this centre employed over 700 staff and had

1160-526: The functions from Rail North. In August 2016, it was reported that proposals for a road tunnel underneath the Pennines to cut journey times by 30 minutes between Manchester and Sheffield, were being advanced. If completed, it would be the world's longest road tunnel. In July 2017 Secretary of State for Transport Chris Grayling , said that it is unlikely that the railway line between Manchester and Leeds will be fully electrified. He also cast doubt on whether

1200-537: The north, the south east and the south west had seen a £4.7 billion rise. Chi Onwurah , the MP for Newcastle Upon Tyne Central , noted that "without real investment, powers and accountability, [The Northern Powerhouse] can never be more than a marketing ploy with a little money attached". She said having elected Mayors (one of the achievements cited by the IPPR) did not improve democracy or create better outcomes, noting that it

1240-631: The planned two extra through platforms at Manchester Piccadilly station would be built. It was also announced that the electrification plan of the Midland Main Line was to be scrapped and InterCity Express Trains ordered would be changed to less efficient bi-mode trains with diesel engines added to run on non-electrified lines. In February 2017 research by the Institute for Public Policy Research showed that actual or planned expenditure on transport infrastructure per head of population

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1280-528: The position of first Secretary of the Secretariat in the same process used to determine the membership and roles of the CCP Politburo Standing Committee. Under this informal process, the first secretary would be chosen during deliberations by incumbent Politburo members and retired Politburo Standing Committee members in the lead up to a Party Congress . The first secretary would later succeed the retiring general secretary as part of

1320-514: The post of chairman of the Central Military Commission , making the holder the supreme commander of the People's Liberation Army . The CCP general secretary is nominally elected by a plenary meeting of the Central Committee of the Chinese Communist Party from among the members of the Politburo Standing Committee . In practice, the de facto method of selecting the general secretary has varied over time. The two most recent general secretaries, Hu Jintao and Xi Jinping , were first elevated to

1360-495: The post of general secretary has been the highest office in the CCP, though it did not become the most powerful post until Deng Xiaoping 's retirement in 1990. Since the mid-1990s, starting with Jiang Zemin , the general secretary has traditionally also held the post of president of China . While the presidency is a ceremonial post, it is customary for the general secretary to assume the presidency to confirm his status as head of state . It has additionally been held together with

1400-613: The project. It was discussed in the Press and praised by then Northern Powerhouse Minister Andrew Percy prior to his resignation from the post in June 2017. In August 2019 Northern Powerhouse Minister Jake Berry announced the Northern Powerhouse Partnership scheme exceeded 300 members. Professor Neil Lee of the London School of Economics commented that while he was "sympathetic to the basic idea",

1440-399: The world's largest economy by GDP purchasing power parity (PPP) , the second largest economy by GDP nominal , the largest military in the world by personnel, a recognized nuclear weapons state , UN Security Council permanent member , and a potential superpower , the general secretary is considered to be one of the world's most powerful political figures. The incumbent general secretary

1480-480: Was not the structure of local government that mattered, but the effectiveness in changing lives. Roger Marsh, Chair of the NP11 Group of Northern Local Enterprise Partnerships said that the Northern Powerhouse needed a coherent strategy that set out a clear vision. He argued that the strategy needed to be designed and led by the North, and must be long-term. “To be truly successful, the Northern Powerhouse must be

1520-554: Was secured from Innovate UK for the years 2018 to 2023. The PMC was based in Cambridge and had regional centres of excellence at Belfast, Glasgow, Cardiff, Oxford, Leeds and Manchester. It worked with precision medicine . It started from April 2015, and worked with regional parts of the Diagnostic Evidence Cooperative and Academic Health Science Networks (AHSN). On 26 June 2017 it was announced that

1560-488: Was subsequently refuted by Theresa May who pledged to "help the great cities and towns of the North pool their strengths and take on the world". In September 2016, one of the main architects of the Northern Powerhouse project, Lord O'Neill , resigned from the Government and quit the Conservative benches in the upper house . Transport for the North (TfN) is set to become the first sub-regional transport body in

1600-657: Was £1,943 in London and £427 in the north of England. In January 2016, the new southern entrance to Leeds station opened, allowing commuters travelling south to reduce their journey times from the station, as well as a new concourse and cycle storage. In December 2017, the Ordsall Chord linking Manchester Piccadilly and Manchester Victoria opened. Projects include the National Graphene Institute , Square Kilometre Array and National Biologics Industrial Innovation Centre. Manchester will get

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