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85-559: Sergio Corbucci ( Italian: [ˈsɛrdʒo korˈbuttʃi] ; 6 December 1926 – 1 December 1990) was an Italian film director , screenwriter and producer . He directed both very violent spaghetti Westerns and bloodless Bud Spencer and Terence Hill action comedies. He is the older brother of screenwriter and film director Bruno Corbucci . Corbucci was born in Rome . He started his career by directing mostly low-budget sword and sandal movies. Among his first spaghetti Westerns were

170-411: A blood test for biomarkers (the cardiac protein troponin ). When there is evidence of an MI, it may be classified as an ST elevation myocardial infarction (STEMI) or Non-ST elevation myocardial infarction (NSTEMI) based on the results of an ECG . The phrase "heart attack" is often used non-specifically to refer to myocardial infarction. An MI is different from—but can cause— cardiac arrest , where

255-475: A coronary artery caused by a rupture of an atherosclerotic plaque is usually the underlying mechanism of an MI. MIs are less commonly caused by coronary artery spasms , which may be due to cocaine , significant emotional stress (often known as Takotsubo syndrome or broken heart syndrome ) and extreme cold, among others. Many tests are helpful to help with diagnosis, including electrocardiograms (ECGs), blood tests and coronary angiography . An ECG, which

340-473: A film school to get a bachelor's degree studying film or cinema. Film students generally study the basic skills used in making a film. This includes, for example, preparation, shot lists and storyboards, blocking, communicating with professional actors, communicating with the crew, and reading scripts. Some film schools are equipped with sound stages and post-production facilities. Besides basic technical and logistical skills, students also receive education on

425-609: A Polish mercenary and the film also starring Tony Musante , Jack Palance and Giovanna Ralli — as well as Compañeros (1970) a.k.a. Vamos a matar, Companeros , which also starred Tomas Milian and Jack Palance . The last film of the "Mexican Revolution" trilogy - The Mercenary and Compañeros being the first two in the installment - was What Am I Doing in the Middle of the Revolution? (1972). After Django , Corbucci made many other spaghetti Westerns, which made him

510-474: A benefit of 15 to 45%. Physical activity can reduce the risk of cardiovascular disease, and people at risk are advised to engage in 150 minutes of moderate or 75 minutes of vigorous intensity aerobic exercise a week. Keeping a healthy weight, drinking alcohol within the recommended limits, and quitting smoking reduce the risk of cardiovascular disease. Substituting unsaturated fats such as olive oil and rapeseed oil instead of saturated fats may reduce

595-428: A common, and sometimes the only symptom, occurring when damage to the heart limits the output of the left ventricle , with breathlessness arising either from low oxygen in the blood or pulmonary edema . Other less common symptoms include weakness, light-headedness , palpitations , and abnormalities in heart rate or blood pressure . These symptoms are likely induced by a massive surge of catecholamines from

680-485: A flat fee for the project, as a weekly salary, or as a daily rate. A handful of top Hollywood directors made from $ 133.3 million to $ 257.95 million in 2011, such as James Cameron and Steven Spielberg , but the average United States film directors and producers made $ 89,840 in 2018. A new Hollywood director typically gets paid around $ 400,000 for directing their first studio film. The average annual salary in England

765-400: A general plotline and let the actors improvise dialogue, while others control every aspect and demand that the actors and crew follow instructions precisely. Some directors also write their own screenplays or collaborate on screenplays with long-standing writing partners. Other directors edit or appear in their films or compose music score for their films. A film director's task is to envisage

850-480: A late consequence of Kawasaki disease . Calcium deposits in the coronary arteries can be detected with CT scans . Calcium seen in coronary arteries can provide predictive information beyond that of classical risk factors. High blood levels of the amino acid homocysteine is associated with premature atherosclerosis; whether elevated homocysteine in the normal range is causal is controversial. In people without evident coronary artery disease , possible causes for

935-431: A myocardial infarction before age 55 years, or a female first-degree relative (mother, sister) less than age 65 increases a person's risk of MI. Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. The strongest association of MI has been found with chromosome 9 on the short arm p at locus 21, which contains genes CDKN2A and 2B, although

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1020-463: A myocardial infarction increases with older age, low physical activity, and low socioeconomic status . Heart attacks appear to occur more commonly in the morning hours, especially between 6AM and noon. Evidence suggests that heart attacks are at least three times more likely to occur in the morning than in the late evening. Shift work is also associated with a higher risk of MI. One analysis has found an increase in heart attacks immediately following

1105-406: A myocardial infarction. Spasm of coronary arteries, such as Prinzmetal's angina may cause blockage. If impaired blood flow to the heart lasts long enough, it triggers a process called the ischemic cascade ; the heart cells in the territory of the blocked coronary artery die ( infarction ), chiefly through necrosis , and do not grow back. A collagen scar forms in their place. When an artery

1190-543: A myocardial infarction. The flow of blood can be imaged, and contrast dyes may be given to improve image. Other scans using radioactive contrast include SPECT CT-scans using thallium , sestamibi ( MIBI scans ) or tetrofosmin ; or a PET scan using Fludeoxyglucose or rubidium-82 . These nuclear medicine scans can visualize the perfusion of heart muscle. SPECT may also be used to determine viability of tissue, and whether areas of ischemia are inducible. Medical societies and professional guidelines recommend that

1275-637: A person localizes the chest pain by clenching one or both fists over their sternum , has classically been thought to be predictive of cardiac chest pain, although a prospective observational study showed it had a poor positive predictive value . Typically, chest pain because of ischemia, be it unstable angina or myocardial infarction, lessens with the use of nitroglycerin , but nitroglycerin may also relieve chest pain arising from non-cardiac causes. Chest pain may be accompanied by sweating , nausea or vomiting, and fainting , and these symptoms may also occur without any pain at all. Dizziness or lightheadedness

1360-407: A previous heart attack is also suggestive. The pain associated with MI is usually diffuse, does not change with position, and lasts for more than 20 minutes. It might be described as pressure, tightness, knifelike, tearing, burning sensation (all these are also manifested during other diseases). It could be felt as an unexplained anxiety, and pain might be absent altogether. Levine's sign , in which

1445-551: A recent trend of more attention to women directors in India, brought on partly by Amazon and Netflix moving into the industry. Of the movies produced in Nollywood , women direct only 2%. There are many different awards for film directing, run by various academies , critics associations , film festivals , and guilds . The Academy Award for Best Director and Cannes Film Festival Award for Best Director are considered among

1530-560: A rise in biomarkers, a rise in the ST segment , changes in the shape or flipping of T waves , new Q waves , or a new left bundle branch block can be used to diagnose an AMI. In addition, ST elevation can be used to diagnose an ST segment myocardial infarction (STEMI). A rise must be new in V2 and V3 ≥2 mm (0,2 mV) for males or ≥1.5 mm (0.15 mV) for females or ≥1 mm (0.1 mV) in two other adjacent chest or limb leads . ST elevation

1615-409: A series of leads placed on a person's chest that measure electrical activity associated with contraction of the heart muscle. The taking of an ECG is an important part of the workup of an AMI, and ECGs are often not just taken once but may be repeated over minutes to hours, or in response to changes in signs or symptoms. ECG readouts produce a waveform with different labeled features. In addition to

1700-406: A significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Trans fats do appear to increase risk. Acute and prolonged intake of high quantities of alcoholic drinks (3–4 or more daily) increases the risk of a heart attack. Family history of ischemic heart disease or MI, particularly if one has a male first-degree relative (father, brother) who had

1785-403: A way to translate a screenplay into a fully formed film, and then to realize this vision. To do this, they oversee the artistic and technical elements of film production. This entails organizing the film crew in such a way to achieve their vision of the film and communicating with the actors. This requires skills of group leadership, as well as the ability to maintain a singular focus even in

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1870-520: A yearly salary from ¥4 million to ¥10 million, and the Directors Guild of Japan requires a minimum payment of ¥3.5 million. Korean directors make 300 million to 500 million won for a film, and beginning directors start out making around 50 million won. A Korean director who breaks into the Chinese market might make 1 billion won for a single film. According to a 2018 report from UNESCO ,

1955-740: Is a film criticism concept that holds that a film director's film reflects the director's personal creative vision, as if they were the primary "auteur" (the French word for "author"). In spite of—and sometimes even because of—the production of the film as part of an industrial process, the auteur's creative voice is distinct enough to shine through studio interference and the collective process. Some film directors started as screenwriters , film editors , producers , actors , or film critics , as well as directing for similar media like television and commercials. Several American cinematographers have become directors, including Barry Sonnenfeld , originally

2040-601: Is a known risk factor, particularly high low-density lipoprotein , low high-density lipoprotein , and high triglycerides . Many risk factors for myocardial infarction are potentially modifiable, with the most important being tobacco smoking (including secondhand smoke ). Smoking appears to be the cause of about 36% and obesity the cause of 20% of coronary artery disease . Lack of physical activity has been linked to 7–12% of cases. Less common causes include stress-related causes such as job stress , which accounts for about 3% of cases, and chronic high stress levels. There

2125-454: Is a recording of the heart's electrical activity, may confirm an ST elevation MI ( STEMI ), if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB . Treatment of an MI is time-critical. Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen

2210-806: Is also an important modifiable risk. Short-term exposure to air pollution such as carbon monoxide , nitrogen dioxide , and sulfur dioxide (but not ozone ) has been associated with MI and other acute cardiovascular events. For sudden cardiac deaths, every increment of 30 units in Pollutant Standards Index correlated with an 8% increased risk of out-of-hospital cardiac arrest on the day of exposure. Extremes of temperature are also associated. A number of acute and chronic infections including Chlamydophila pneumoniae , influenza , Helicobacter pylori , and Porphyromonas gingivalis among others have been linked to atherosclerosis and myocardial infarction. Myocardial infarction can also occur as

2295-499: Is associated with infarction, and may be preceded by changes indicating ischemia, such as ST depression or inversion of the T waves. Abnormalities can help differentiate the location of an infarct, based on the leads that are affected by changes. Early STEMIs may be preceded by peaked T waves. Other ECG abnormalities relating to complications of acute myocardial infarctions may also be evident, such as atrial or ventricular fibrillation . Noninvasive imaging plays an important role in

2380-517: Is blocked, cells lack oxygen , needed to produce ATP in mitochondria . ATP is required for the maintenance of electrolyte balance, particularly through the Na/K ATPase . This leads to an ischemic cascade of intracellular changes, necrosis and apoptosis of affected cells. Cells in the area with the worst blood supply, just below the inner surface of the heart ( endocardium ), are most susceptible to damage. Ischemia first affects this region,

2465-433: Is common and occurs due to reduction in oxygen and blood to the brain. In females, the most common symptoms of myocardial infarction include shortness of breath, weakness, and fatigue . Females are more likely to have unusual or unexplained tiredness and nausea or vomiting as symptoms. Females having heart attacks are more likely to have palpitations, back pain, labored breath, vomiting, and left arm pain than males, although

2550-477: Is not the only cause of myocardial infarction, but it may exacerbate or contribute to other causes. A myocardial infarction may result from a heart with a limited blood supply subject to increased oxygen demands, such as in fever, a fast heart rate , hyperthyroidism , too few red blood cells in the bloodstream , or low blood pressure . Damage or failure of procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass grafts (CABG) may cause

2635-430: Is one of the most common symptoms of acute myocardial infarction and is often described as a sensation of tightness, pressure, or squeezing. Pain radiates most often to the left arm, but may also radiate to the lower jaw, neck, right arm, back, and upper abdomen . The pain most suggestive of an acute MI, with the highest likelihood ratio , is pain radiating to the right arm and shoulder. Similarly, chest pain similar to

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2720-414: Is recommended in those with low oxygen levels or shortness of breath. In a STEMI, treatments attempt to restore blood flow to the heart and include percutaneous coronary intervention (PCI), where the arteries are pushed open and may be stented , or thrombolysis , where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction ( NSTEMI ) are often managed with

2805-949: Is retrosternal chest pain or discomfort that classically radiates to the left shoulder, arm, or jaw. The pain may occasionally feel like heartburn . This is the dangerous type of Acute coronary syndrome . Other symptoms may include shortness of breath , nausea , feeling faint , a cold sweat , feeling tired , and decreased level of consciousness . About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure , an irregular heartbeat , cardiogenic shock or cardiac arrest . Most MIs occur due to coronary artery disease . Risk factors include high blood pressure , smoking , diabetes , lack of exercise , obesity , high blood cholesterol , poor diet, and excessive alcohol intake . The complete blockage of

2890-412: Is still unable to be distributed to the affected myocardium despite clearing the occlusion—also contributes to myocardial injury. Topical endothelial swelling is one of many factors contributing to this phenomenon. A myocardial infarction, according to current consensus, is defined by elevated cardiac biomarkers with a rising or falling trend and at least one of the following: A myocardial infarction

2975-457: Is usually clinically classified as an ST-elevation MI (STEMI) or a non-ST elevation MI (NSTEMI). These are based on ST elevation , a portion of a heartbeat graphically recorded on an ECG . STEMIs make up about 25–40% of myocardial infarctions. A more explicit classification system, based on international consensus in 2012, also exists. This classifies myocardial infarctions into five types: There are many different biomarkers used to determine

3060-445: Is varying evidence about the importance of saturated fat in the development of myocardial infarctions. Eating polyunsaturated fat instead of saturated fats has been shown in studies to be associated with a decreased risk of myocardial infarction, while other studies find little evidence that reducing dietary saturated fat or increasing polyunsaturated fat intake affects heart attack risk. Dietary cholesterol does not appear to have

3145-738: Is £50,440, in Canada is $ 62,408, and in Western Australia it can range from $ 75,230 to $ 97,119. In France, the average salary is €4000 per month, paid per project. Luc Besson was the highest paid French director in 2017, making €4.44 million for Valerian and the City of a Thousand Planets . That same year, the top ten French directors' salaries in total represented 42% of the total directors' salaries in France. Film directors in Japan average

3230-661: The elderly , in those with diabetes mellitus and after heart transplantation . In people with diabetes, differences in pain threshold , autonomic neuropathy , and psychological factors have been cited as possible explanations for the lack of symptoms. In heart transplantation, the donor heart is not fully innervated by the nervous system of the recipient. The most prominent risk factors for myocardial infarction are older age, actively smoking , high blood pressure , diabetes mellitus , and total cholesterol and high-density lipoprotein levels. Many risk factors of myocardial infarction are shared with coronary artery disease ,

3315-480: The health impact assessment of regional and local plans and policies. Most guidelines recommend combining different preventive strategies. A 2015 Cochrane Review found some evidence that such an approach might help with  blood pressure ,  body mass index  and  waist circumference . However, there was insufficient evidence to show an effect on mortality or actual cardio-vascular events. Statins , drugs that act to lower blood cholesterol, decrease

3400-522: The single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9 , SORT1 , MIA3 , WDR12 , MRAS , PHACTR1 , LPA , TCF21 , MTHFDSL , ZC3HC1 , CDKN2A , 2B , ABO , PDGF0 , APOA5 , MNF1ASM283 , COL4A1 , HHIPC1 , SMAD3 , ADAMTS7 , RAS1 , SMG6 , SNF8 , LDLR , SLC5A3 , MRPS6 , KCNE2 . The risk of having

3485-481: The subendocardial region, and tissue begins to die within 15–30 minutes of loss of blood supply. The dead tissue is surrounded by a zone of potentially reversible ischemia that progresses to become a full-thickness transmural infarct. The initial "wave" of infarction can take place over 3–4 hours. These changes are seen on gross pathology and cannot be predicted by the presence or absence of Q waves on an ECG. The position, size and extent of an infarct depends on

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3570-551: The sympathetic nervous system , which occurs in response to pain and, where present, low blood pressure . Loss of consciousness can occur in myocardial infarctions due to inadequate blood flow to the brain and cardiogenic shock , and sudden death , frequently due to the development of ventricular fibrillation . When the brain was without oxygen for too long due to a myocardial infarction, coma and persistent vegetative state can occur. Cardiac arrest, and atypical symptoms such as palpitations , occur more frequently in females,

3655-1123: The Berlin/Brandenburg TV station RBB (Berlin-Brandenburg Broadcasting) and ARTE . In recent decades American directors have primarily been coming out of USC , UCLA , AFI , Columbia University , and NYU , each of which is known for cultivating a certain style of filmmaking. Notable film schools outside of the United States include Beijing Film Academy , Centro de Capacitación Cinematográfica in Mexico City, Dongseo University in South Korea, FAMU in Prague, Film and Television Institute of India , HFF Munich , La Fémis in Paris, Tel Aviv University , and Vancouver Film School . Film directors usually are self-employed and hired per project based on recommendations and industry reputation. Compensation might be arranged as

3740-528: The Coen brothers' Director of Photography; Wally Pfister , cinematographer on Christopher Nolan 's three Batman films made his directorial debut with Transcendence (2014). Despite the misnomer, assistant director has become a completely separate career path and is not typically a position for aspiring directors, but there are exceptions in some countries such as India where assistant directors are indeed directors-in-training. Many film directors have attended

3825-585: The Italian box office and found wide distribution in European countries like Germany, France, Austria and Switzerland, but were barely released overseas. His movies were rarely taken seriously by contemporary critics and he was considered an exploitation director, but Corbucci has managed to attain a cult reputation. He died in Rome in 1990, at age 63, of a heart attack . His nephew Leonardo Corbucci continues

3910-474: The United States. In the developed world, the risk of death in those who have had a STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010. In 2011, an MI was one of the top five most expensive conditions during inpatient hospitalizations in the US, with a cost of about $ 11.5 billion for 612,000 hospital stays. Myocardial infarction (MI) refers to tissue death ( infarction ) of

3995-627: The Yellow and the Black (1975), with Tomas Milian and Eli Wallach . Corbucci's Westerns were dark and brutal, with the characters portrayed as sadistic antiheroes . His films featured very high body counts and scenes of mutilation. Django especially is considered to have set a new level for violence in Westerns. In the 1970s and 1980s Corbucci mostly directed comedies, often starring Adriano Celentano . Many of these comedies were huge successes at

4080-432: The acute diagnostic algorithm; however, it can confirm a clinical suspicion of Chronic Coronary Syndrome when the patient's history, physical examination (including cardiac examination ) ECG, and cardiac biomarkers suggest coronary artery disease. Echocardiography , an ultrasound scan of the heart, is able to visualize the heart, its size, shape, and any abnormal motion of the heart walls as they beat that may indicate

4165-409: The affected artery, totality of the blockage, duration of the blockage, the presence of collateral blood vessels , oxygen demand, and success of interventional procedures. Tissue death and myocardial scarring alter the normal conduction pathways of the heart and weaken affected areas. The size and location put a person at risk of abnormal heart rhythms (arrhythmias) or heart block , aneurysm of

4250-647: The blood thinner heparin , with the additional use of PCI in those at high risk. In people with blockages of multiple coronary arteries and diabetes, coronary artery bypass surgery (CABG) may be recommended rather than angioplasty . After an MI, lifestyle modifications, along with long-term treatment with aspirin, beta blockers and statins , are typically recommended. Worldwide, about 15.9 million myocardial infarctions occurred in 2015. More than 3 million people had an ST elevation MI, and more than 4 million had an NSTEMI. STEMIs occur about twice as often in men as women. About one million people have an MI each year in

4335-467: The cast and crew and creates an overall vision through which a film eventually becomes realized or noticed. Directors need to be able to mediate differences in creative visions and stay within the budget . There are many pathways to becoming a film director. Some film directors started as screenwriters , cinematographers , producers , film editors or actors. Other film directors have attended film school. Directors use different approaches. Some outline

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4420-405: The diagnosis and characterisation of myocardial infarction. Tests such as chest X-rays can be used to explore and exclude alternate causes of a person's symptoms. Echocardiography may assist in modifying clinical suspicion of ongoing myocardial infarction in patients that can't be ruled out or ruled in following initial ECG and Troponin testing. Myocardial perfusion imaging has no role in

4505-616: The diagnostic accuracy of troponin testing is improving over time. One high-sensitivity cardiac troponin can rule out a heart attack as long as the ECG is normal. Other tests, such as CK-MB or myoglobin , are discouraged. CK-MB is not as specific as troponins for acute myocardial injury, and may be elevated with past cardiac surgery, inflammation or electrical cardioversion; it rises within 4–8 hours and returns to normal within 2–3 days. Copeptin may be useful to rule out MI rapidly when used along with troponin. Electrocardiograms (ECGs) are

4590-422: The director ensures that all individuals involved in the film production are working towards an identical vision for the completed film. The set of varying challenges they have to tackle has been described as "a multi-dimensional jigsaw puzzle with egos and weather thrown in for good measure". It adds to the pressure that the success of a film can influence when and how they will work again, if at all. Generally,

4675-435: The director works with the editor to edit the material into the director's cut . Well-established directors have the " final cut privilege ", meaning that they have the final say on which edit of the film is released. For other directors, the studio can order further edits without the director's permission. The director is one of the few positions that requires intimate involvement during every stage of film production . Thus,

4760-414: The elderly, those with diabetes, in people who have just had surgery, and in critically ill patients. "Silent" myocardial infarctions can happen without any symptoms at all. These cases can be discovered later on electrocardiograms , using blood enzyme tests, or at autopsy after a person has died. Such silent myocardial infarctions represent between 22 and 64% of all infarctions, and are more common in

4845-478: The film industry throughout the world has a disproportionately higher number of male directors compared to female directors, and they provide as an example the fact that only 20% of films in Europe are directed by women. 44% of graduates from a sample of European films schools are women, and yet women are only 24% of working film directors in Europe. However only a fraction of film school graduates aspire to direct with

4930-539: The films Grand Canyon Massacre (1964), which he co-directed (under the pseudonym, Stanley Corbett) with Albert Band , as well as Minnesota Clay (1964), his first solo directed spaghetti Western. Corbucci's first commercial success was with the cult spaghetti Western Django , starring Franco Nero , the leading man in many of his movies. He would later collaborate with Franco Nero on two other spaghetti Westerns, Il Mercenario or The Mercenary (a.k.a. A Professional Gun ) (1968) — where Nero played Sergei Kowalski,

5015-637: The greatest support is the Mediterranean diet . Vitamins and mineral supplements are of no proven benefit, and neither are plant stanols or sterols . Public health measures may also act at a population level to reduce the risk of myocardial infarction, for example by reducing unhealthy diets (excessive salt, saturated fat, and trans-fat) including food labeling and marketing requirements as well as requirements for catering and restaurants and stimulating physical activity. This may be part of regional cardiovascular disease prevention programs or through

5100-465: The heart is not contracting at all or so poorly that all vital organs cease to function, thus leading to death. It is also distinct from heart failure , in which the pumping action of the heart is impaired. However, an MI may lead to heart failure. Chest pain that may or may not radiate to other parts of the body is the most typical and significant symptom of myocardial infarction. It might be accompanied by other symptoms such as sweating. Chest pain

5185-410: The heart muscle ( myocardium ) caused by ischemia , the lack of oxygen delivery to myocardial tissue. It is a type of acute coronary syndrome , which describes a sudden or short-term change in symptoms related to blood flow to the heart. Unlike the other type of acute coronary syndrome, unstable angina , a myocardial infarction occurs when there is cell death , which can be estimated by measuring by

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5270-441: The heart ventricles , inflammation of the heart wall following infarction, and rupture of the heart wall that can have catastrophic consequences. Injury to the myocardium also occurs during re-perfusion. This might manifest as ventricular arrhythmia. The re-perfusion injury is a consequence of the calcium and sodium uptake from the cardiac cells and the release of oxygen radicals during reperfusion. No-reflow phenomenon—when blood

5355-729: The heart, lungs , gastrointestinal tract , aorta , and other muscles, bones and nerves surrounding the chest. In addition to myocardial infarction, other causes include angina , insufficient blood supply ( ischemia ) to the heart muscles without evidence of cell death, gastroesophageal reflux disease ; pulmonary embolism , tumors of the lungs, pneumonia , rib fracture , costochondritis , heart failure and other musculoskeletal injuries. Rarer severe differential diagnoses include aortic dissection , esophageal rupture , tension pneumothorax , and pericardial effusion causing cardiac tamponade . The chest pain in an MI may mimic heartburn . Causes of sudden-onset breathlessness generally involve

5440-402: The incidence and mortality rates of myocardial infarctions. They are often recommended in those at an elevated risk of cardiovascular diseases. Aspirin has been studied extensively in people considered at increased risk of myocardial infarction. Based on numerous studies in different groups (e.g. people with or without diabetes), there does not appear to be a benefit strong enough to outweigh

5525-568: The legacy of film directors in the family in Los Angeles. In 2021 was released a documentary about Corbucci, directed by Luca Rea, Django & Django , that relies to a considerable extent on an interview with Quentin Tarantino. In 2022 German thrash metal band Kreator released the instrumental song "Sergio Corbucci is Dead" as an intro to their album Hate Über Alles . According to vocalist/guitarist Mille Petrozza , "Sergio Corbucci

5610-666: The lungs or heart – including pulmonary edema , pneumonia, allergic reactions and asthma , and pulmonary embolus, acute respiratory distress syndrome and metabolic acidosis . There are many different causes of fatigue, and myocardial infarction is not a common cause. There is a large crossover between the lifestyle and activity recommendations to prevent a myocardial infarction, and those that may be adopted as secondary prevention after an initial myocardial infarction, because of shared risk factors and an aim to reduce atherosclerosis affecting heart vessels. The influenza vaccine also appear to protect against myocardial infarction with

5695-472: The majority entering the industry in other roles. In Hollywood, women make up only 12.6 percent of film directors, as reported by a UCLA study of the 200 top theatrical films of 2017, but that number is a significant increase from 6.9% in 2016. As of 2014, there were only 20 women in the Directors Guild of Japan out of the 550 total members. Indian film directors are also greatly underrepresented by women, even compared to other countries, but there has been

5780-507: The most prestigious awards for directing, and there is even an award for worst directing given out during the Golden Raspberry Awards . Myocardial infarction A myocardial infarction ( MI ), commonly known as a heart attack , occurs when blood flow decreases or stops in one of the coronary arteries of the heart , causing infarction (tissue death) to the heart muscle . The most common symptom

5865-447: The most successful Italian Western director after Sergio Leone and one of Italy's most productive and prolific directors. His most famous of these pictures was The Great Silence (Il Grande Silenzio), a dark and gruesome Western starring a mute action hero and a psychopathic bad guy. The film was banned in some countries for its excessive display of violence. Corbucci also directed Navajo Joe (1966), starring Burt Reynolds as

5950-610: The myocardial infarction are coronary spasm or coronary artery dissection . The most common cause of a myocardial infarction is the rupture of an atherosclerotic plaque on an artery supplying heart muscle. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that blocks the artery; this can occur in minutes. Blockage of an artery can lead to tissue death in tissue being supplied by that artery. Atherosclerotic plaques are often present for decades before they result in symptoms. The gradual buildup of cholesterol and fibrous tissue in plaques in

6035-548: The nature of professional relationships that occur during film production. A full degree course can be designed for up to five years of studying. Future directors usually complete short films during their enrollment. The National Film School of Denmark has the student's final projects presented on national TV. Some film schools retain the rights for their students' works. Many directors successfully prepared for making feature films by working in television. The German Film and Television Academy Berlin consequently cooperates with

6120-419: The physician confirm a person is at high risk for Chronic Coronary Syndrome before conducting diagnostic non-invasive imaging tests to make a diagnosis, as such tests are unlikely to change management and result in increased costs. Patients who have a normal ECG and who are able to exercise, for example, most likely do not merit routine imaging. There are many causes of chest pain , which can originate from

6205-471: The plaque and act to stabilize it. A stable plaque may have a thick fibrous cap with calcification . If there is ongoing inflammation, the cap may be thin or ulcerate. Exposed to the pressure associated with blood flow, plaques, especially those with a thin lining, may rupture and trigger the formation of a blood clot (thrombus). The cholesterol crystals have been associated with plaque rupture through mechanical injury and inflammation. Atherosclerotic disease

6290-415: The position of film director is widely considered to be a highly stressful and demanding one. It has been said that "20-hour days are not unusual". Some directors also take on additional roles, such as producing, writing or editing. Under European Union law, the film director is considered the "author" or one of the authors of a film, largely as a result of the influence of auteur theory . Auteur theory

6375-487: The presence of cardiac muscle damage. Troponins , measured through a blood test, are considered to be the best, and are preferred because they have greater sensitivity and specificity for measuring injury to the heart muscle than other tests. A rise in troponin occurs within 2–3 hours of injury to the heart muscle, and peaks within 1–2 days. The level of the troponin, as well as a change over time, are useful in measuring and diagnosing or excluding myocardial infarctions, and

6460-512: The primary cause of myocardial infarction, with other risk factors including male sex, low levels of physical activity, a past family history , obesity , and alcohol use . Risk factors for myocardial disease are often included in risk factor stratification scores, such as the Framingham Risk Score . At any given age, men are more at risk than women for the development of cardiovascular disease. High levels of blood cholesterol

6545-407: The restrictions of the film's budget and the demands of the producer and studio (such as the need to get a particular age rating ). Directors also play an important role in post-production . While the film is still in production, the director sends " dailies " to the film editor and explains their overall vision for the film, allowing the editor to assemble an editor's cut . In post-production,

6630-486: The risk of myocardial infarction, although there is not universal agreement. Dietary modifications are recommended by some national authorities, with recommendations including increasing the intake of wholegrain starch, reducing sugar intake (particularly of refined sugar), consuming five portions of fruit and vegetables daily, consuming two or more portions of fish per week, and consuming 4–5 portions of unsalted nuts , seeds , or legumes per week. The dietary pattern with

6715-403: The sole superiors of the director are the producers and the studio that is financing the film, although sometimes the director can also be a producer of the same film. The role of a director differs from producers in that producers typically manage the logistics and business operations of the production, whereas the director is tasked with making creative decisions. The director must work within

6800-399: The start of daylight saving time . Women who use combined oral contraceptive pills have a modestly increased risk of myocardial infarction, especially in the presence of other risk factors. The use of non-steroidal anti inflammatory drugs (NSAIDs), even for as short as a week, increases risk. Endometriosis in women under the age of 40 is an identified risk factor. Air pollution

6885-477: The stressful, fast-paced environment of a film set. Moreover, it is necessary to have an artistic eye to frame shots and to give precise feedback to cast and crew, thus, excellent communication skills are a must. Because the film director depends on the successful cooperation of many different creative individuals with possibly strongly contradicting artistic ideals and visions, they also need to possess conflict-resolution skills to mediate whenever necessary. Thus

6970-400: The studies showing these differences had high variability. Females are less likely to report chest pain during a heart attack and more likely to report nausea, jaw pain, neck pain, cough, and fatigue, although these findings are inconsistent across studies. Females with heart attacks also had more indigestion, dizziness , loss of appetite , and loss of consciousness. Shortness of breath is

7055-423: The title character, a Navajo Indian opposing a group of bandits that killed his tribe, as well as The Hellbenders (1967), and Johnny Oro (1966) a.k.a. Ringo and his Golden Pistol starring Mark Damon . Other spaghetti Westerns he directed include Gli specialisti ( Drop Them or I'll Shoot , 1969), La Banda J.S.: Cronaca criminale del Far West ( Sonny and Jed , 1972), with Tomas Milian and The White

7140-529: The wall of the coronary arteries or other arteries, typically over decades, is termed atherosclerosis . Atherosclerosis is characterized by progressive inflammation of the walls of the arteries. Inflammatory cells, particularly macrophages , move into affected arterial walls. Over time, they become laden with cholesterol products, particularly LDL , and become foam cells . A cholesterol core forms as foam cells die. In response to growth factors secreted by macrophages, smooth muscle and other cells move into

7225-450: Was someone who was very anti-authoritarian in his film. In all his films he has a protagonist who rebels against the authorities. Often these characters are very obscure. I was wondering if there are still people like that who make really political films without trying to preach anything to you. It's a bit of a dig at the bands who don't speak their minds out of fear of losing fans." Film director The film director gives direction to

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