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89-616: Since 1970, the Robert Koch Foundation has awarded prizes for major advances in the biomedical sciences, particularly in the fields of microbiology and immunology . The prestige of this award has grown over the past decades so that it is now widely regarded as the leading international scientific prize in microbiology. As has been described by a jury member for the prize, the committee often asks, "What would Robert Koch work on today?” to decide on research that should be granted recognition. The more specific Robert Koch Prize

178-489: A Jain householder is the voluntary ritual practice of "assuming temporary ascetic status". There are many rituals in Jainism's various sects. According to Dundas, the ritualistic lay path among Śvētāmbara Jains is "heavily imbued with ascetic values", where the rituals either revere or celebrate the ascetic life of tirthankaras, or progressively approach the psychological and physical life of an ascetic. The ultimate ritual

267-567: A Jain mendicant for the period. Śvētāmbara Jains do similarly in the eight day paryusana with samvatsari-pratikramana . The practice is believed to remove karma from one's soul and provides merit ( punya ). A "one day" fast lasts about 36 hours, starting at sunset before the day of the fast and ending 48 minutes after sunrise the day after. Among laypeople, fasting is more commonly observed by women, as it shows their piety and religious purity, gains merit earning and helps ensure future well-being for their family. Some religious fasts are observed in

356-436: A biological science. One of his students, Adrien Certes, is considered the founder of marine microbiology. Pasteur also designed methods for food preservation ( pasteurization ) and vaccines against several diseases such as anthrax , fowl cholera and rabies . Koch is best known for his contributions to the germ theory of disease , proving that specific diseases were caused by specific pathogenic microorganisms. He developed

445-424: A body are called Siddhas (liberated souls). Only a soul with human body can attain enlightenment and liberation. The liberated beings are the supreme beings and are worshipped by all heavenly, earthly and hellish beings who aspire to attain liberation themselves. Purification of soul and liberation can be achieved through the path of three jewels: Samyak Darśana (Correct View), meaning faith, acceptance of

534-411: A duty to rescue all creatures", but resulting from "continual self-discipline", a cleansing of the soul that leads to one's own spiritual development which ultimately affects one's salvation and release from rebirths. Jains believe that causing injury to any being in any form creates bad karma which affects one's rebirth, future well-being and causes suffering. Late medieval Jain scholars re-examined

623-471: A predominantly lacto-vegetarian lifestyle. Parasparopagraho jīvānām (the function of souls is to help one another) is the faith's motto, and the Namokar Mantra is its most common and strongest prayer. Jainism is one of the oldest religions still practiced today. It has two major ancient sub-traditions, Digambaras and Śvētāmbaras , which hold different views on ascetic practices, gender, and

712-469: A series of criteria that have become known as the Koch's postulates . Koch was one of the first scientists to focus on the isolation of bacteria in pure culture resulting in his description of several novel bacteria including Mycobacterium tuberculosis , the causative agent of tuberculosis . While Pasteur and Koch are often considered the founders of microbiology, their work did not accurately reflect

801-528: A social and supportive female group. Long fasts are celebrated by friends and families with special ceremonies. Jainism considers meditation ( dhyana ) a necessary practice, but its goals are very different from those in Buddhism and Hinduism. In Jainism, meditation is concerned more with stopping karmic attachments and activity, not as a means to transformational insights or self-realization in other Indian religions. According to Padmanabh Jaini , Sāmāyika

890-411: A stricter vow by eating only once a day. Jains fast particularly during festivals. This practice is called upavasa , tapasya or vrata , and may be practiced according to one's ability. Digambaras fast for Dasa-laksana-parvan , eating only one or two meals per day, drinking only boiled water for ten days, or fasting completely on the first and last days of the festival, mimicking the practices of

979-665: A universal religious tolerance", and a teaching of "plurality" and "benign attitude to other [ethical, religious] positions". Dundas states this is a misreading of historical texts and Mahāvīra's teachings. According to him, the "many pointedness, multiple perspective" teachings of the Mahāvīra is about the nature of absolute reality and human existence. He claims that it is not about condoning activities such as killing animals for food, nor violence against disbelievers or any other living being as "perhaps right". The five vows for Jain monks and nuns, for example, are strict requirements and there

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1068-476: A variety of preclinical models. Some bacteria are used to study fundamental mechanisms. An example of model bacteria used to study motility or the production of polysaccharides and development is Myxococcus xanthus . Jainism Jainism ( / ˈ dʒ eɪ n ɪ z əm / JAY -niz-əm ), also known as Jain Dharma , is an Indian religion . Jainism traces its spiritual ideas and history through

1157-472: A very short life, said to pervade every part of the universe, even in tissues of plants and flesh of animals. The Roman Marcus Terentius Varro made references to microbes when he warned against locating a homestead in the vicinity of swamps "because there are bred certain minute creatures which cannot be seen by the eyes, which float in the air and enter the body through the mouth and nose and thereby cause serious diseases." Persian scientists hypothesized

1246-400: Is anekāntavāda , from anekānta ("many-sidedness," etymologically " non -oneness" or "not being one") and vada ("doctrine"). The doctrine states that truth and reality are complex and always have multiple aspects. It further states that reality can be experienced, but cannot be fully expressed with language. It suggests that human attempts to communicate are Naya , "partial expression of

1335-440: Is sallekhana , a religious death through ascetic abandonment of food and drinks. The Digambara Jains follow the same theme, but the life cycle and religious rituals are closer to a Hindu liturgy. The overlap is mainly in the life cycle (rites-of-passage) rituals, and likely developed because Jain and Hindu societies overlapped, and rituals were viewed as necessary and secular. Jains ritually worship numerous deities, especially

1424-1022: Is a "religious death" ritual observed at the end of life, historically by Jain monks and nuns, but rare in the modern age. In this vow, there is voluntary and gradual reduction of food and liquid intake to end one's life by choice and with dispassion, This is believed to reduce negative karma that affects a soul's future rebirths. Of the major Indian religions, Jainism has had the strongest ascetic tradition. Ascetic life may include nakedness, symbolizing non-possession even of clothes, fasting, body mortification, and penance, to burn away past karma and stop producing new karma, both of which are believed essential for reaching siddha and moksha ("liberation from rebirths" and "salvation"). Jain texts like Tattvartha Sūtra and Uttaradhyayana Sūtra discuss austerities in detail. Six outer and six inner practices are oft-repeated in later Jain texts. Outer austerities include complete fasting, eating limited amounts, eating restricted items, abstaining from tasty foods, mortifying

1513-985: Is a fundamental tenet of Jainism. It holds that one must abandon all violent activity and that without such a commitment to non-violence all religious behavior is worthless. In Jain theology, it does not matter how correct or defensible the violence may be, one must not kill or harm any being, and non-violence is the highest religious duty. Jain texts such as Ācārāṅga Sūtra and Tattvarthasūtra state that one must renounce all killing of living beings, whether tiny or large, movable or immovable. Its theology teaches that one must neither kill another living being, nor cause another to kill, nor consent to any killing directly or indirectly. Furthermore, Jainism emphasizes non-violence against all beings not only in action but also in speech and in thought. It states that instead of hate or violence against anyone, "all living creatures must help each other". Jains believe that violence negatively affects and destroys one's soul, particularly when

1602-478: Is a practice of "brief periods in meditation" in Jainism that is a part of siksavrata (ritual restraint). The goal of Sāmāyika is to achieve equanimity, and it is the second siksavrata . The samayika ritual is practiced at least three times a day by mendicants, while a layperson includes it with other ritual practices such as Puja in a Jain temple and doing charity work. According to Johnson, as well as Jaini, samayika connotes more than meditation, and for

1691-421: Is a sin in Jainism, with negative karmic effects. Jainism states that souls begin in a primordial state, and either evolve to a higher state or regress if driven by their karma. It further clarifies that abhavya (incapable) souls can never attain moksha (liberation). It explains that the abhavya state is entered after an intentional and shockingly evil act. Souls can be good or evil in Jainism, unlike

1780-570: Is a wandering mendicant in the Digambara tradition, or a resident mendicant in the Śvētāmbara tradition. For Jain laypersons, it recommends limited possession of property that has been honestly earned, and giving excess property to charity. According to Natubhai Shah, aparigraha applies to both the material and the psychic. Material possessions refer to various forms of property. Psychic possessions refer to emotions, likes and dislikes, and attachments of any form. Unchecked attachment to possessions

1869-518: Is accepted as a truth, as in Hinduism but not Buddhism. The cycle of rebirths has a definite beginning and end in Jainism. Jain theosophy asserts that each soul passes through 8,400,000 birth-situations as they circle through Saṃsāra , going through five types of bodies: earth bodies, water bodies, fire bodies, air bodies and vegetable lives, constantly changing with all human and non-human activities from rainfall to breathing. Harming any life form

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1958-543: Is called devapuja , and is found in all Jain sub-traditions. Typically, the Jain layperson enters the Derasar (Jain temple) inner sanctum in simple clothing and bare feet with a plate filled with offerings, bows down, says the namaskar , completes his or her litany and prayers, sometimes is assisted by the temple priest, leaves the offerings and then departs. Jain practices include performing abhisheka (ceremonial bath) of

2047-517: Is commonly considered one of the stepping-stones (along with other prizes such as the Lasker Award ) to eventual Nobel Prize recognition for scientists in the fields of microbiology and immunology, and a number of Robert Koch Prize winners subsequently became Nobel laureates, such as César Milstein , Susumu Tonegawa and Harald zur Hausen . Other notable awardees include Albert Sabin , Jonas Salk and John Enders for their pioneering work on

2136-420: Is considered a father of microbiology as he used simple single-lensed microscopes of his own design. While Van Leeuwenhoek is often cited as the first to observe microbes, Robert Hooke made his first recorded microscopic observation, of the fruiting bodies of moulds , in 1665. It has, however, been suggested that a Jesuit priest called Athanasius Kircher was the first to observe microorganisms. Kircher

2225-426: Is considered as "faith in the tattvas ". The spiritual goal in Jainism is to reach moksha for ascetics, but for most Jain laypersons, it is to accumulate good karma that leads to better rebirth and a step closer to liberation. Jain philosophy accepts three reliable means of knowledge ( pramana ). It holds that correct knowledge is based on perception ( pratyaksa ), inference ( anumana ) and testimony ( sabda or

2314-446: Is encouraged if there are concerns about animal welfare. Jain monks, nuns and some followers avoid root vegetables such as potatoes, onions, and garlic because tiny organisms are injured when the plant is pulled up, and because a bulb or tuber's ability to sprout is seen as characteristic of a higher living being. Jain monks and advanced lay people avoid eating after sunset, observing a vow of ratri-bhojana-tyaga-vrata . Monks observe

2403-554: Is essential for spiritual progress and the attainment of samyak darshan or self realization , which marks the beginning of the aspirant's journey towards liberation . The three main pillars of Jainism are ahiṃsā (non-violence), anekāntavāda (non-absolutism), and aparigraha (asceticism). Jain monks take five main vows: ahiṃsā (non-violence), satya (truth), asteya (not stealing), brahmacharya (chastity), and aparigraha (non-possessiveness). These principles have affected Jain culture in many ways, such as leading to

2492-481: Is no "perhaps" about them. Similarly, since ancient times, Jainism co-existed with Buddhism and Hinduism according to Dundas, but Jainism disagreed, in specific areas, with the knowledge systems and beliefs of these traditions, and vice versa. The third main principle in Jainism is aparigraha which means non-attachment to worldly possessions. For monks and nuns, Jainism requires a vow of complete non-possession of any property, relations and emotions. The ascetic

2581-448: Is not" to metaphysical questions. The Mahāvīra, in contrast, taught his followers to accept both "it is", and "it is not", qualified with "perhaps", to understand Absolute Reality. The permanent being is conceptualized as jiva (soul) and ajiva (matter) within a dualistic anekāntavāda framework. According to Paul Dundas , in contemporary times the anekāntavāda doctrine has been interpreted by some Jains as intending to "promote

2670-458: Is observed by Jains as the anniversary of Mahāvīra's attainment of moksha . The Hindu festival of Diwali is also celebrated on the same date ( Kartika Amavasya ). Jain temples, homes, offices, and shops are decorated with lights and diyas (small oil lamps). The lights are symbolic of knowledge or removal of ignorance. Sweets are often distributed. On Diwali morning, Nirvan Ladoo is offered after praying to Mahāvīra in all Jain temples across

2759-429: Is said to result in direct harm to one's personality. Jainism teaches five ethical duties, which it calls five vows. These are called anuvratas (small vows) for Jain laypersons, and mahavratas (great vows) for Jain mendicants. For both, its moral precepts preface that the Jain has access to a guru (teacher, counsellor), deva (Jina, god), doctrine, and that the individual is free from five offences: doubts about

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2848-678: Is the scientific study of microorganisms , those being of unicellular (single-celled), multicellular (consisting of complex cells), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology , bacteriology , protistology , mycology , immunology , and parasitology . Eukaryotic microorganisms possess membrane-bound organelles and include fungi and protists , whereas prokaryotic organisms—all of which are microorganisms—are conventionally classified as lacking membrane-bound organelles and include Bacteria and Archaea . Microbiologists traditionally relied on culture, staining, and microscopy for

2937-451: Is the case with bacteriology , mycology , protozoology , virology , phycology , and microbial ecology . There is considerable overlap between the specific branches of microbiology with each other and with other disciplines, and certain aspects of these branches can extend beyond the traditional scope of microbiology A pure research branch of microbiology is termed cellular microbiology . While some people have fear of microbes due to

3026-701: Is treated as absolute. The doctrine is ancient, found in Buddhist texts such as the Samaññaphala Sutta . The Jain Agamas suggest that Mahāvīra's approach to answering all metaphysical philosophical questions was a "qualified yes" ( syāt ). These texts identify anekāntavāda as a key difference from the Buddha 's teachings. The Buddha taught the Middle Way, rejecting extremes of the answer "it is" or "it

3115-531: The Jinas . In Jainism a Jina as deva is not an avatar (incarnation), but the highest state of omniscience that an ascetic tirthankara achieved. Out of the 24 tirthankaras, Jains predominantly worship four: Mahāvīra, Parshvanatha , Neminatha and Rishabhanatha . Among the non- tirthankara saints, devotional worship is common for Bahubali among the Digambaras. The Panch Kalyanaka rituals remember

3204-611: The Ahiṃsā doctrine when faced with external threat or violence. For example, they justified violence by monks to protect nuns. According to Dundas , the Jain scholar Jinadattasuri wrote during a time of destruction of temples and persecution that "anybody engaged in a religious activity who was forced to fight and kill somebody would not lose any spiritual merit but instead attain deliverance". However, examples in Jain texts that condone fighting and killing under certain circumstances are relatively rare. The second main principle of Jainism

3293-691: The Rishi-mandala including the tirthankaras . The Jain tantric traditions use mantra and rituals that are believed to accrue merit for rebirth realms. The most important annual Jain festival is called the Paryushana by Svetambaras and Dasa lakshana parva by the Digambaras. It is celebrated from the 12th day of the waning moon in the traditional lunisolar month of Bhadrapada in the Indian calendar . This typically falls in August or September of

3382-414: The ajiva (non-living). Jains distinguish a substance from a complex body, or thing, by declaring the former a simple indestructible element, while the latter is a compound made of one or more substances that can be destroyed. Tattva connotes reality or truth in Jain philosophy and is the framework for salvation. According to Digambara Jains, there are seven tattvas : the sentient ( jiva or living),

3471-458: The nondualism of some forms of Hinduism and Buddhism. According to Jainism, a Siddha (liberated soul) has gone beyond Saṃsāra , is at the apex, is omniscient, and remains there eternally. Jain texts propound that the universe consists of many eternal lokas (realms of existence). As in Buddhism and Hinduism, both time and the universe are eternal, but the universe is transient. The universe, body, matter and time are considered separate from

3560-450: The tirthankaras guiding every time cycle of the cosmology . Central to understanding Jain philosophy is the concept of bhedvigyān , or the clear distinction in the nature of the soul and non-soul entities. This principle underscores the innate purity and potential for liberation within every soul , distinct from the physical and mental elements that bind it to the cycle of birth and rebirth . Recognizing and internalizing this separation

3649-433: The tobacco mosaic virus established the basic principles of virology, it was his development of enrichment culturing that had the most immediate impact on microbiology by allowing for the cultivation of a wide range of microbes with wildly different physiologies. Winogradsky was the first to develop the concept of chemolithotrophy and to thereby reveal the essential role played by microorganisms in geochemical processes. He

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3738-443: The yeast two-hybrid system . Bacteria can be used for the industrial production of amino acids . organic acids , vitamin , proteins , antibiotics and other commercially used metabolites which are produced by microorganisms. Corynebacterium glutamicum is one of the most important bacterial species with an annual production of more than two million tons of amino acids, mainly L-glutamate and L-lysine. Since some bacteria have

3827-534: The 2011 census. Outside India, some of the largest Jain communities can be found in Canada , Europe , and the United States . Japan is also home to a fast-growing community of converts. Major festivals include Paryushana and Das Lakshana , Ashtanika , Mahavir Janma Kalyanak , Akshaya Tritiya , and Dipawali . Jainism is transtheistic and forecasts that the universe evolves without violating

3916-522: The Gregorian calendar. It lasts eight days for Svetambaras, and ten days among the Digambaras. It is a time when lay people fast and pray. The five vows are emphasized during this time. Svetambaras recite the Kalpasūtras , while Digambaras read their own texts. The festival is an occasion where Jains make active effort to stop cruelty towards other life forms, freeing animals in captivity and preventing

4005-478: The Jain text Tattvartha sūtra , the first two are indirect knowledge and the remaining three are direct knowledge. According to Jainism, the existence of "a bound and ever changing soul" is a self-evident truth, an axiom which does not need to be proven. It maintains that there are numerous souls, but every one of them has three qualities ( Guṇa ): consciousness ( chaitanya , the most important), bliss ( sukha ) and vibrational energy ( virya ). It further claims

4094-546: The Jesuit priest Athanasius Kircher was likely the first to see microbes, which he mentioned observing in milk and putrid material in 1658. Antonie van Leeuwenhoek is considered a father of microbiology as he observed and experimented with microscopic organisms in the 1670s, using simple microscopes of his design. Scientific microbiology developed in the 19th century through the work of Louis Pasteur and in medical microbiology Robert Koch . The existence of microorganisms

4183-463: The Mahāvīra (Vardhamana) set an example by performing severe austerities for twelve years. Monastic organization, sangh , has a four-fold order consisting of sadhu (male ascetics, muni ), sadhvi (female ascetics, aryika ), śrāvaka (laymen), and śrāvikā (laywomen). The latter two support the ascetics and their monastic organizations called gacch or samuday , in autonomous regional Jain congregations. Jain monastic rules have encouraged

4272-503: The Plague) in 1658, stating correctly that the disease was caused by microbes, though what he saw was most likely red or white blood cells rather than the plague agent itself. The field of bacteriology (later a subdiscipline of microbiology) was founded in the 19th century by Ferdinand Cohn , a botanist whose studies on algae and photosynthetic bacteria led him to describe several bacteria including Bacillus and Beggiatoa . Cohn

4361-493: The ability to synthesize antibiotics, they are used for medicinal purposes, such as Streptomyces to make aminoglycoside antibiotics . A variety of biopolymers , such as polysaccharides , polyesters , and polyamides , are produced by microorganisms. Microorganisms are used for the biotechnological production of biopolymers with tailored properties suitable for high-value medical application such as tissue engineering and drug delivery. Microorganisms are for example used for

4450-584: The association of some microbes with various human diseases, many microbes are also responsible for numerous beneficial processes such as industrial fermentation (e.g. the production of alcohol , vinegar and dairy products ), antibiotic production can act as molecular vehicles to transfer DNA to complex organisms such as plants and animals. Scientists have also exploited their knowledge of microbes to produce biotechnologically important enzymes such as Taq polymerase , reporter genes for use in other genetic systems and novel molecular biology techniques such as

4539-477: The biosynthesis of xanthan , alginate , cellulose , cyanophycin , poly(gamma-glutamic acid), levan , hyaluronic acid , organic acids, oligosaccharides polysaccharide and polyhydroxyalkanoates. Microorganisms are beneficial for microbial biodegradation or bioremediation of domestic, agricultural and industrial wastes and subsurface pollution in soils, sediments and marine environments. The ability of each microorganism to degrade toxic waste depends on

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4628-456: The body of a heavenly celestial do so because of their positive karma. It is further stated that they possess a more transcendent knowledge about material things and can anticipate events in the human realms. However, once their past karmic merit is exhausted, it is explained that their souls are reborn again as humans, animals or other beings. The perfect enlightened souls with a body are called Arihants (victors) and perfect souls without

4717-549: The clinical effects traced to them were originally presumed due to chronic viral infections, virologists took a search—discovering "infectious proteins". The existence of microorganisms was predicted many centuries before they were first observed, for example by the Jains in India and by Marcus Terentius Varro in ancient Rome. The first recorded microscope observation was of the fruiting bodies of moulds, by Robert Hooke in 1666, but

4806-673: The development of polio vaccines. Only Enders was recognized with a Nobel Prize, together with Thomas Huckle Weller and Frederick Chapman Robbins . Two separate Robert Koch Awards are presented annually: The Gold Robert Koch Gold Medal for accumulated excellence in biomedical research and the Robert Koch Prize, worth €120,000, for a major discovery in biomedical science. Source: Microbiology Microbiology (from Ancient Greek μῑκρος ( mīkros )  'small' βίος ( bíos )  ' life ' and -λογία ( -logía )  'study of')

4895-564: The digestive system) or prebiotics (substances consumed to promote the growth of probiotic microorganisms). The ways the microbiome influences human and animal health, as well as methods to influence the microbiome are active areas of research. Research has suggested that microorganisms could be useful in the treatment of cancer . Various strains of non-pathogenic clostridia can infiltrate and replicate within solid tumors . Clostridial vectors can be safely administered and their potential to deliver therapeutic proteins has been demonstrated in

4984-497: The existence of microorganisms, such as Avicenna in his book The Canon of Medicine , Ibn Zuhr (also known as Avenzoar) who discovered scabies mites, and Al-Razi who gave the earliest known description of smallpox in his book The Virtuous Life (al-Hawi). The tenth-century Taoist Baoshengjing describes "countless micro organic worms" which resemble vegetable seeds, which prompted Dutch sinologist Kristofer Schipper to claim that "the existence of harmful bacteria

5073-413: The faith, indecisiveness about the truths of Jainism, insincerity of desire for Jain teachings, non-recognition of fellow Jains, and insufficient admiration of fellow Jains' spiritual endeavors. Such a person undertakes the following Five vows of Jainism: Jainism prescribes seven supplementary vows, including three guņa vratas (merit vows) and four śikşā vratas . The Sallekhana (or Santhara ) vow

5162-452: The first eon the universe generates, and in the next it degenerates. Thus, it divides the worldly cycle of time into two half-cycles, utsarpiṇī (ascending, progressive prosperity and happiness) and avasarpiṇī (descending, increasing sorrow and immorality). It states that the world is currently in the fifth ara of avasarpiṇī , full of sorrow and religious decline, where the height of living beings shrinks. According to Jainism, after

5251-543: The five life events of the tirthankaras , including the Panch Kalyanaka Pratishtha Mahotsava , Panch Kalyanaka Puja and Snatrapuja . The basic ritual is darsana (seeing) of deva , which includes Jina, or other yaksas , gods and goddesses such as Brahmadeva, 52 Viras, Padmavati , Ambika and 16 Vidyadevis (including Sarasvati and Lakshmi ). Terapanthi Digambaras limit their ritual worship to tirthankaras. The worship ritual

5340-445: The flesh, and guarding the flesh (avoiding anything that is a source of temptation). Inner austerities include expiation, confession, respecting and assisting mendicants , studying, meditation, and ignoring bodily wants in order to abandon the body. Lists of internal and external austerities vary with the text and tradition. Asceticism is viewed as a means to control desires, and to purify the jiva (soul). The tirthankaras such as

5429-403: The images. Some Jain sects employ a pujari (also called upadhye ), who may be a Hindu, to perform priestly duties at the temple. More elaborate worship includes offerings such as rice, fresh and dry fruits, flowers, coconut, sweets, and money. Some may light up a lamp with camphor and make auspicious marks with sandalwood paste. Devotees also recite Jain texts, particularly the life stories of

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5518-454: The insentient ( ajiva or non-living), the karmic influx to the soul ( Āsrava , which is a mix of living and non-living), the bondage of karmic particles to the soul ( Bandha ), the stoppage of karmic particles ( Saṃvara ), the wiping away of past karmic particles ( Nirjarā ), and the liberation ( Moksha ). Śvētāmbaras add two further tattvas , namely good karma ( Punya ) and bad karma ( Paapa ). The true insight in Jain philosophy

5607-643: The isolation and identification of microorganisms. However, less than 1% of the microorganisms present in common environments can be cultured in isolation using current means. With the emergence of biotechnology , Microbiologists currently rely on molecular biology tools such as DNA sequence-based identification, for example, the 16S rRNA gene sequence used for bacterial identification. Viruses have been variably classified as organisms because they have been considered either very simple microorganisms or very complex molecules. Prions , never considered microorganisms, have been investigated by virologists; however, as

5696-558: The law of substance dualism , and the actual realization of this principle plays out through the phenomena of both parallelism and interactionism . Dravya means substances or entity in Sanskrit . Jains believe the universe is made up of six eternal substances: sentient beings or souls ( jīva ), non-sentient substance or matter ( pudgala ), the principle of motion ( dharma ), the principle of rest ( adharma ), space ( ākāśa ), and time ( kāla ). The last five are united as

5785-508: The lunisolar month of Chaitra in the traditional Indian calendar. This typically falls in March or April of the Gregorian calendar. The festivities include visiting Jain temples, pilgrimages to shrines, reading Jain texts and processions of Mahāvīra by the community. At his legendary birthplace of Kundagrama in Bihar , north of Patna, special events are held by Jains. The next day of Dipawali

5874-595: The nature of each contaminant . Since sites typically have multiple pollutant types, the most effective approach to microbial biodegradation is to use a mixture of bacterial and fungal species and strains, each specific to the biodegradation of one or more types of contaminants. Symbiotic microbial communities confer benefits to their human and animal hosts health including aiding digestion, producing beneficial vitamins and amino acids, and suppressing pathogenic microbes. Some benefit may be conferred by eating fermented foods, probiotics (bacteria potentially beneficial to

5963-520: The other hand, wear seamless white clothes. During Chandragupta Maurya's reign, Jain tradition states that Acharya Bhadrabahu predicted a twelve-year-long famine and moved to Karnataka with his disciples. Sthulabhadra , a pupil of Acharya Bhadrabahu, is believed to have stayed in Magadha. Later, as stated in tradition, when followers of Acharya Bhadrabahu returned, they found those who had remained at Magadha had started wearing white clothes, which

6052-575: The sixth ara , the universe will be reawakened in a new cycle. Jainism is a transtheistic religion, holding that the universe was not created , and will exist forever. It is independent, having no creator, governor, judge, or destroyer. In this, it is unlike the Abrahamic religions and the theistic strands of Hinduism , but similar to Buddhism. However, Jainism believes in the world of heavenly and hellish beings who are born, die and are reborn like earthly beings. The souls who live happily in

6141-500: The slaughter of animals. Forgiveness I forgive all living beings, may all living beings forgive me. All in this world are my friends, I have no enemies. — Jain festival prayer on the last day The last day involves a focused prayer and meditation session known as Samvatsari . Jains consider this a day of atonement, granting forgiveness to others, seeking forgiveness from all living beings, physically or mentally asking for forgiveness and resolving to treat everyone in

6230-461: The soul ( jiva ). Their interaction explains life, living, death and rebirth in Jain philosophy. The Jain cosmic universe has three parts, the upper, middle, and lower worlds ( urdhva loka , madhya loka , and adho loka ). Jainism states that Kāla (time) is without beginning and eternal; the cosmic wheel of time, kālachakra , rotates ceaselessly. In this part of the universe, it explains, there are six periods of time within two eons ( ara ), and in

6319-454: The soul, travel with the soul in bound form between rebirths, and affect the suffering and happiness experienced by the jiva in the lokas . Karma is believed to obscure and obstruct the innate nature and striving of the soul, as well as its spiritual potential in the next rebirth. The conceptual framework of the Saṃsāra doctrine differs between Jainism and other Indian religions. Soul ( jiva )

6408-411: The succession of twenty-four tirthankara s (supreme preachers of Dharma ), with the first in the current time cycle being Rishabhadeva , whom the tradition holds to have lived millions of years ago, the twenty-third tirthankara Parshvanatha , whom historians date to the 9th century BCE , and the twenty-fourth tirthankara Mahavira , around 600 BCE. Jainism is considered an eternal dharma with

6497-451: The texts considered canonical. Both sub-traditions have mendicants supported by laypersons ( śrāvakas and śrāvikas ). The Śvētāmbara tradition in turn has two sub-traditions: Deravasi, also known as Mandirmargis, and Sthānakavasī. The religion has between four and five million followers, known as Jains or Jainas , who reside mostly in India , where they numbered around 4.5 million at

6586-465: The tirthankaras. Traditional Jains, like Buddhists and Hindus, believe in the efficacy of mantras and that certain sounds and words are inherently auspicious, powerful and spiritual. The most famous of the mantras, broadly accepted in various sects of Jainism, is the "five homage" ( panca namaskara ) mantra which is believed to be eternal and existent since the first tirthankara's time. Medieval worship practices included making tantric diagrams of

6675-439: The true diversity of the microbial world because of their exclusive focus on microorganisms having direct medical relevance. It was not until the late 19th century and the work of Martinus Beijerinck and Sergei Winogradsky that the true breadth of microbiology was revealed. Beijerinck made two major contributions to microbiology: the discovery of viruses and the development of enrichment culture techniques. While his work on

6764-542: The truth of soul ( jīva ); Samyak Gyana (Correct Knowledge), meaning undoubting knowledge of the tattvas ; and Samyak Charitra (Correct Conduct), meaning behavior consistent with the Five vows. Jain texts often add samyak tapas (Correct Asceticism) as a fourth jewel, emphasizing belief in ascetic practices as the means to liberation ( moksha ). The four jewels are called Moksha Marga (the path of liberation). The principle of ahimsa (non-violence or non-injury)

6853-459: The truth". According to it, one can experience the taste of truth, but cannot fully express that taste through language. It holds that attempts to express experience are syāt , or valid "in some respect", but remain "perhaps, just one perspective, incomplete". It concludes that in the same way, spiritual truths can be experienced but not fully expressed. It suggests that the great error is belief in ekānta (one-sidedness), where some relative truth

6942-485: The use of mouth cover, as well as the Dandasan – a long stick with woolen threads – to gently remove ants and insects that may come in their path. The practice of non-violence towards all living beings has led to Jain culture being vegetarian . Devout Jains practice lacto-vegetarianism , meaning that they eat no eggs, but accept dairy products if there is no violence against animals during their production. Veganism

7031-406: The vibration draws karmic particles to the soul and creates bondages, but is also what adds merit or demerit to the soul. Jain texts state that souls exist as "clothed with material bodies", where it entirely fills up the body. Karma, as in other Indian religions, connotes in Jainism the universal cause and effect law. However, it is envisioned as a material substance (subtle matter) that can bind to

7120-433: The violence is done with intent, hate or carelessness, or when one indirectly causes or consents to the killing of a human or non-human living being. The doctrine exists in Hinduism and Buddhism, but is most highly developed in Jainism. The theological basis of non-violence as the highest religious duty has been interpreted by some Jain scholars not to "be driven by merit from giving or compassion to other creatures, nor

7209-559: The word of scriptures). These ideas are elaborated in Jain texts such as Tattvarthasūtra , Parvacanasara , Nandi and Anuyogadvarini . Some Jain texts add analogy ( upamana ) as the fourth reliable means, in a manner similar to epistemological theories found in other Indian religions. In Jainism, jnāna (knowledge) is said to be of five kinds – mati jñāna (sensory knowledge), śrutu jñāna (scriptural knowledge), avadhi jñāna ( clairvoyance ), manah prayāya Jñāna ( telepathy ) and kevala jnana ( omniscience ). According to

7298-411: The world as friends. Forgiveness is asked by saying " Micchami Dukkadam " or " Khamat khamna " to others. This means, "If I have offended you in any way, knowingly or unknowingly, in thought, word or action, then I seek your forgiveness." The literal meaning of Paryushana is "abiding" or "coming together". Mahavir Janma Kalyanak celebrates the birth of Mahāvīra. It is celebrated on the 13th day of

7387-547: The world. The Jain new year starts right after Diwali. Some other festivals celebrated by Jains are Akshaya Tritiya and Raksha Bandhan , similar to those in the Hindu communities. The Jain community is divided into two major denominations , Digambara and Śvētāmbara . Monks of the Digambara (sky-clad) tradition do not wear clothes. Female monastics of the Digambara sect wear unstitched plain white sarees and are referred to as Aryikas . Śvētāmbara (white-clad) monastics, on

7476-545: Was known to the Chinese of the time." In 1546, Girolamo Fracastoro proposed that epidemic diseases were caused by transferable seedlike entities that could transmit infection by direct or indirect contact, or vehicle transmission. In 1676, Antonie van Leeuwenhoek , who lived most of his life in Delft , Netherlands, observed bacteria and other microorganisms using a single-lens microscope of his own design . He

7565-470: Was also the first to formulate a scheme for the taxonomic classification of bacteria, and to discover endospores . Louis Pasteur and Robert Koch were contemporaries of Cohn, and are often considered to be the fathers of modern microbiology and medical microbiology , respectively. Pasteur is most famous for his series of experiments designed to disprove the then widely held theory of spontaneous generation , thereby solidifying microbiology's identity as

7654-464: Was among the first to design magic lanterns for projection purposes, and so he was well acquainted with the properties of lenses. He wrote "Concerning the wonderful structure of things in nature, investigated by Microscope" in 1646, stating "who would believe that vinegar and milk abound with an innumerable multitude of worms." He also noted that putrid material is full of innumerable creeping animalcules. He published his Scrutinium Pestis (Examination of

7743-471: Was hypothesized for many centuries before their actual discovery. The existence of unseen microbiological life was postulated by Jainism which is based on Mahavira 's teachings as early as 6th century BCE (599 BC - 527 BC). Paul Dundas notes that Mahavira asserted the existence of unseen microbiological creatures living in earth, water, air and fire. Jain scriptures describe nigodas which are sub-microscopic creatures living in large clusters and having

7832-456: Was responsible for the first isolation and description of both nitrifying and nitrogen-fixing bacteria . French-Canadian microbiologist Felix d'Herelle co-discovered bacteriophages in 1917 and was one of the earliest applied microbiologists. Joseph Lister was the first to use phenol disinfectant on the open wounds of patients. The branches of microbiology can be classified into applied sciences, or divided according to taxonomy, as

7921-512: Was unacceptable to the others who remained naked. This is how Jains believe the Digambara and Śvētāmbara schism began, with the former being naked while the latter wore white clothes. Digambara saw this as being opposed to the Jain tenet of aparigraha which, according to them, required not even possession of clothes, i.e. complete nudity. In the fifth-century CE, the Council of Valabhi was organized by Śvētāmbara, which Digambara did not attend. At

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