Runs of homozygosity (ROH) are contiguous lengths of homozygous genotypes that are present in an individual due to parents transmitting identical haplotypes to their offspring.
9-832: (Redirected from Roh ) [REDACTED] Look up ROH , roh , róh , or röh in Wiktionary, the free dictionary. Roh or ROH may refer to: Roh (film) , a 2019 Malaysian horror film Roh (name) , a given name or surname, including a list of people with the name Roh (historical region) , in present-day Pakistan and Afghanistan Roh, Maré , New Caledonia Revoluční odborové hnutí , labour union in Czechoslovakia 1945–1990 Ring of Honor , American wrestling promotion Royal Opera House , London, England Runs of homozygosity , in DNA sequencing Formula of
18-427: A generic alcohol (substituent R, Oxygen, Hydrogen) Romansh language , ISO 639 language code roh See also [ edit ] All pages with titles beginning with ROH All pages with titles beginning with Roh Topics referred to by the same term [REDACTED] This disambiguation page lists articles associated with the title ROH . If an internal link led you here, you may wish to change
27-427: A generic alcohol (substituent R, Oxygen, Hydrogen) Romansh language , ISO 639 language code roh See also [ edit ] All pages with titles beginning with ROH All pages with titles beginning with Roh Topics referred to by the same term [REDACTED] This disambiguation page lists articles associated with the title ROH . If an internal link led you here, you may wish to change
36-498: A particular genetic disorder but indicates an increased risk of autosomal recessive inherited diseases. As ROHs smaller than 3 Mb spread throughout the genome are common even in outbred populations, these segments were usually thought to not be important enough to report. Large ROH can be indicative of uniparental isodisomy with follow-up testing to rule out false positives, there is currently no consistent reporting standards among different laboratories. ROH can be used to detect
45-489: A subpopulation is the proportion of the autosomal genome above a specified length, termed F roh . A research study in UK Biobank , All of Us and Million Veteran Program found that F ROH declines over time. This technique can be used to identify the genomic footprint of inbreeding in conservation programs, as organisms that have undergone recent inbreeding will exhibit long runs of homozygosity. For example,
54-508: The free dictionary. Roh or ROH may refer to: Roh (film) , a 2019 Malaysian horror film Roh (name) , a given name or surname, including a list of people with the name Roh (historical region) , in present-day Pakistan and Afghanistan Roh, Maré , New Caledonia Revoluční odborové hnutí , labour union in Czechoslovakia 1945–1990 Ring of Honor , American wrestling promotion Royal Opera House , London, England Runs of homozygosity , in DNA sequencing Formula of
63-472: The link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=ROH&oldid=1256766057 " Category : Disambiguation pages Hidden categories: Short description is different from Wikidata All article disambiguation pages All disambiguation pages ROH [REDACTED] Look up ROH , roh , róh , or röh in Wiktionary,
72-435: The link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=ROH&oldid=1256766057 " Category : Disambiguation pages Hidden categories: Short description is different from Wikidata All article disambiguation pages All disambiguation pages Runs of homozygosity The potential of predicting or estimating individual autozygosity for
81-538: The step-wise reintroduction strategy of the Alpine Ibex in the Swiss Alps created several strong population bottlenecks that reduced the genetic diversity of the newly introduced individuals. The effect of inbreeding in the resulting sub-populations could be studied by measuring the runs of homozygosity in different individuals. In clinical laboratory testing, the detection of ROH in itself does not indicate
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