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California Pacific Medical Center

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Sutter Health California Pacific Medical Center (CPMC) is a general medical/surgical and teaching hospital in San Francisco, California . It was created by a merger of some of the city's longest established hospitals and currently operates three acute care campuses.

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129-1055: Its primary campuses in San Francisco are the Van Ness Campus in The Tenderloin , the Davies Campus in Duboce Triangle , and the Mission Bernal Campus in the Mission District . While it is a privately funded entity, CPMC has strong academic ties to the University of California, San Francisco ( UCSF ) and Stanford University Medical Center , as well as the Geisel School of Medicine of Dartmouth College . As of 2020, CPMC operates three acute care hospitals: With

258-505: A 14.5-acre parcel brought the total campus area to about 57 acres. The Mission Bay expansion was overseen by a one-year chancellorship of surgeon Haile Debas . Under his guidance, UCSF further increased its lead in the field of surgery, transplant surgery, and surgical training. The Mission Bay Campus doubled the university's research and provided new opportunities for biomedical discovery and student training. The first phase of construction cost $ 800 million and included four research buildings,

387-691: A Mardi Gras Ball at California Hall on Polk Street sponsored by the Council on Religion and the Homosexual , lining up and photographing 600 participants and arresting several prominent citizens. One of the first "gay riots", pre-dating the Stonewall riots in New York, happened at Compton's Cafeteria at Turk and Taylor Streets in August 1966 when the police, attempting to arrest a drag queen, sparked

516-568: A building as part of a settlement regarding alleged theft of UCSF technology several decades earlier. Also located on the Mission Bay campus, the Arthur and Toni Rembe Rock Hall was designed by César Pelli and opened in February 2004. The building is named in honor of Arthur Rock and his wife, who made a $ 25 million gift to the university. Byers Hall serves as the headquarters for

645-607: A cell therapy development, manufacturing and collaboration center on the school's Mission Bay campus. UCSF operates four major campus sites within the city of San Francisco and one in Fresno, California , as well as numerous other minor sites scattered through San Francisco and the San Francisco Bay Area . The Parnassus Heights campus was the site of the Affiliated Colleges, which later evolved into

774-534: A community center, a student housing complex, two parking structures, and development of large open spaces. Scientist J. Michael Bishop , a Nobel Prize in Medicine recipient, became the eighth Chancellor in 1998. He oversaw one of UCSF's transition and growth periods, including the expanding Mission Bay development and philanthropic support recruitment. During his tenure, he unveiled the first comprehensive, campus-wide, strategic plan to promote diversity and foster

903-641: A downtown residential community since shortly after the California Gold Rush in 1849. However, the name "Tenderloin" does not appear on any maps of San Francisco prior to the 1930s; before then, it was labeled as "Downtown", although it was informally referred to as "the Tenderloin" as early as the 1890s. The area had an active nightlife in the late 19th century with many theaters, restaurants and hotels. Notorious madam Tessie Wall opened her first brothel on O'Farrell Street in 1898. Almost all of

1032-409: A few of these historic gay bars and clubs still exist. The apartment where Dashiell Hammett wrote The Maltese Falcon was once in the boundaries of the Tenderloin at the corner of Hyde and Post. Both the movie and book were based in San Francisco's Tenderloin. There is also an alley in what is now Nob Hill , named for the book's author ( Dashiell Hammett ). It lies outside the Tenderloin because

1161-458: A fitness and recreation center, swimming pools, student services, and conference facilities. The building is named in honor of William J. Rutter , former chairman of the university's Department of Biochemistry & Biophysics and co-founder of Chiron Corporation . A housing complex for 750 students and postdoctoral fellows and an 800-space parking garage also opened in late 2005. And a fourth research building, designed by Rafael Viñoly and named

1290-658: A gym, swimming pool and fitness center among other amenities. The funding for this center was made possible by a $ 1.5 billion bequest from Joan Kroc, the widow of McDonald's founder, Ray Kroc . Adjacent to the Kroc center is Railton Place, a 110-unit apartment complex run by the Salvation Army for former foster youth, homeless veterans, and adults recovering from addictions. In 2016, the Tenderloin Community Benefit District (TLCBD) announced

1419-407: A hotel basement, where he was living, in the Tenderloin district. In the 2020s, the Tenderloin has experienced many of San Francisco's fentanyl deaths. High prevalence of sex work in the Tenderloin area has been associated with a high rate of sexually transmitted infections, including HIV, especially among men who have sex with other men and those who inject drugs . Contributing factors include

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1548-425: A lack of sex education and safe sex practices, including condom use. In a 2000 survey, 59% of men who performed sex with other men did not report condom use, with higher rates of unsafe sex practices among those who are not engaged in paid sex work. Due to Tenderloin's numerous health and safety concerns, the property value in the district is very low compared to other areas of the city. As such it has been feared by

1677-892: A large joint physician group was established in 1993. The new multiple-facility entity was named California Pacific Medical Center (CPMC). Its two sites were renamed the California Campus (the Children's site, which ran along California Street) and the Pacific Campus (the Pacific Presbyterian site). The new hospital began its life by refusing to recognize the California Nurses Association , which had represented registered nurses at Children's Hospital since 1947. The merged hospital also struggled to reduce costs, finally succeeding when

1806-463: A letter proposing renaming of the neighborhood and suggesting an alternative name like the Tempeh District, claiming "the city deserves a neighborhood named after a delicious cruelty-free food instead of the flesh of an abused animal". The proposal was widely met with ridicule from locals, and Mayor Lee responded that it was more important to improve the lives of the residents than to rename

1935-464: A long history as a center of alternate sexualities, including several historic confrontations with police. The legendary female impersonator Ray Bourbon , a performer during the Pansy Craze , was arrested in 1933 while his show "Boys Will Be Girls" was being broadcast live on the radio from Taits Cafe at 44 Ellis Street. In the evening of August 13, 1961, 103 gay and lesbian patrons were raided in

2064-528: A makeshift tent city in Golden Gate Park and were treated by the faculty of the Affiliated Colleges. This brought the Affiliated Colleges, which until then were located on the western outskirts of the city, in contact with significant population numbers. By fueling the Affiliated Colleges' commitment to civic responsibility and health care, the earthquake increased the momentum towards the eventual construction of their own healthcare facilities. Within

2193-559: A month after the 1906 earthquake, the faculty of the medical school voted to make room in their building for a teaching hospital by moving the three departments responsible for the first two years of preclinical instruction—anatomy, pathology, and physiology—across San Francisco Bay to the Berkeley campus. As a result, for over 50 years, students pursuing the M.D. degree took their first two years at Berkeley and their last two years at Parnassus Heights. By October 1906, an outpatient clinic

2322-483: A need for additional space. The nursing school opened its own building in 1972 and the medical center opened the Ambulatory Care Center in 1973. The discovery of recombinant DNA technology by UCSF and Stanford scientists in the mid-1970s opened many new avenues of research and attracted more people. UCSF scientists also played a central role in the birth and development of the biotechnology industry in

2451-801: A new management team took what opponents described as "a ruthless approach." The new CPMC inherited from Presbyterian Hospital its membership in the California HealthCare System; members also included Marin General Hospital, Alta Bates Hospital in Berkeley, and Mills-Peninsula Medical Center in San Mateo and Burlingame. This system joined with the Sutter Health System of Sacramento in 1996 to form Sutter/CHS, later renamed Sutter Health . A major project of

2580-603: A part of the process for getting County permission to build the new facilities, CPMC has committed to maintaining or increasing its services to the city's poor. On June 5, 2015, surgeons at CPMC and University of California, San Francisco successfully completed 18 surgeries in the nation's first nine-way, two-day kidney transplant chain in a single city. CPMC hosts the California Pacific Medical Center Research Institute , which conducts basic science and clinical studies into

2709-465: A range of topics. Michael Rowbotham, M.D. is Senior Scientist and Scientific Director of the research institute. Research and other initiatives at CPMC's Center for Melanoma Research and Treatment have yielded five-year survival rates for metastatic melanoma that are double the national average . Clinical trials led by senior scientists David Minor, MD, and Mohammed Kashani-Sabet, MD, were key to FDA approval of nivolumab—a new breakthrough cancer therapy—for

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2838-468: A reduction in the district's police resources. The Tenderloin serves as a mecca for the art scene in San Francisco, housing the "White Walls" gallery and "Shooting Gallery". The Tenderloin has been home to mural work by artists such as Johanna Poethig , Banksy , Shepard Fairey , Barry McGee , and Blek le Rat . The Tenderloin has been the home of Raphael House , the first provider in the city of shelter for homeless parents and children, since 1971. It

2967-553: A refugee camp". Public defecation and urination are commonplace, and between 2015 and 2018, more than 300 lampposts were replaced because they had been corroded by urine. The neighborhood was the origin of a notorious Bahala Na Gang (BNG) imported from the Philippines . In the late 1960s to the mid-1970s, the gang was involved in extortion, drug sales, and murder for hire. Additionally, on April 10, 1984, notorious serial killer Richard Ramirez committed his first known murder in

3096-411: A reputation for crime and has among the highest levels of homelessness and crime in the city. It is the center of the fentanyl crisis in San Francisco . The Tenderloin took its name from an older neighborhood in New York with similar characteristics. There are several explanations of how that neighborhood was named. Some attribute the name to a New York City police captain, Alexander S. Williams , who

3225-565: A riot that spilled into the streets. The group ended up smashing the windows of the police car and burned a nearby newspaper stand to the ground; the riot promoted the formation of the Gay Activists Alliance . Prior to the emergence of The Castro as a major gay village , the center of the Tenderloin at Turk and Taylor and the Polk Gulch at the western side of the Tenderloin were two of the city's first gay neighborhoods;

3354-511: A supportive work environment. During this time, UCSF also adopted a new mission: "advancing health worldwide"™. In 2009, Susan Desmond-Hellmann became the ninth Chancellor and first woman to lead UCSF. She was tasked with guiding the university through the aftermath of the financial crisis of 2007–2008 . In the same year, UCSF professor Elizabeth Blackburn won the Nobel Prize for Medicine and in 2012 UCSF professor Shinya Yamanaka won

3483-510: A year of events. That same year Neonatologist and Dean of the UCSF School of Medicine Sam Hawgood , MBBS, became the tenth Chancellor. In 2015, the Mission Bay campus saw the opening of the new UCSF Medical Center at Mission Bay, a 289-bed integrated hospital complex serving children, women and cancer patients. Since 2015 UCSF has increased its focus on novel biomedical research and has attracted many acts of philanthropy. UCSF became one of

3612-836: Is a partner in this consortium. UCSF is home to the Industry Documents Library (IDL), a digital library of previously secret internal industry documents, including over 14 million documents in the internationally known Truth Tobacco Industry Documents , the Food Industry Documents Archive, Chemical Industry Documents Archive and the Drug Industry Documents Archive. The IDL contains millions of documents created by major companies related to their advertising, manufacturing, marketing, sales, and scientific research activities. University of California, San Francisco

3741-557: Is also located at the Parnassus campus. It is a center for the diagnosis, treatment, and research of all areas of eye care, including vision correction surgery . Also located on the Parnassus campus is the UCSF Fetal Treatment Center , a multidisciplinary care center dedicated to the diagnosis, treatment, and long-term follow-up of fetal birth defects. UCSF's Mission Bay Campus, also located in San Francisco,

3870-492: Is an ethnically diverse community, consisting of families, young people living in cheap apartments, downtown bohemian artists, and recent immigrants from Latin America and Southeast Asia. It is home to a large population of homeless, those living in extreme poverty, and numerous non-profit social service agencies, soup kitchens, religious rescue missions, homeless shelters and single room occupancy hotels. Many homeless youths in

3999-546: Is built on the site of a previous speakeasy , Bourbon and Branch, at the corner of Jones and O'Farrell Streets. The original speakeasy was restored in the bar's basement, including many of the original decorations. Many bars have entertainment including the historic drag bar Aunt Charlie's. Larger live music venues include the Great American Music Hall and the Warfield Theatre . Historically,

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4128-573: Is frequented by parents and children from the neighborhood. The "Tenderloin National Forest" (a project of the nonprofit organization The Luggage Store/509 Cultural Center) is an unofficial park that was established in 1987 that maintains the park and opening hours. It is located on Cohen Alley just off Ellis Street. In March 2011, People for the Ethical Treatment of Animals (PETA) Vice President Tracy Reiman sent Mayor Ed Lee

4257-433: Is the largest ongoing biomedical construction project in the world. The 43-acre (17 ha) Mission Bay campus, opened in 2003 with construction still ongoing, contains additional research space and facilities to foster biotechnology and life sciences companies. It will double the size of UCSF's research enterprise over the next 10 years. The biotechnology company Genentech contributed $ 50 million toward construction of

4386-402: Is tied with that of Nike Inc. co-founder Phil Knight for the largest single donation ever to a public university. In 2017, UCSF launched a capital campaign, The Campaign, to raise $ 5 billion to increase the endowment and funds for research and medical services. In 2018, UCSF received a commitment of $ 500 million for the construction of a new hospital, which will be built at Parnassus, replacing

4515-487: Is unique among University of California campuses in that it performs only biomedical and patient-centered research in its Schools of Medicine , Pharmacy , Nursing , and Dentistry , and the Graduate Division, and their hundreds of associated laboratories. The university is known for innovation in medical research, public service, and patient care. UCSF's faculty includes 7 Nobel Prize winners , 31 members of

4644-544: The U.S. News & World Report . UCSF has 3,000 full-time faculty. Among its 2018 faculty members are: The UCSF school of medicine is the oldest in the Western United States. In 2021, the School of Medicine was the second-highest recipient of National Institutes of Health research funds among all U.S. medical schools, receiving awards totaling $ 630 million. In 2016, the School of Medicine launched

4773-704: The California Institute for Quantitative Biosciences (QB3) , a cooperative effort between the UC campuses at San Francisco, Berkeley, and Santa Cruz. The building is named after venture capitalist Brook Byers , co-chair of UCSF's capital campaign that concluded in 2005 and raised over $ 1.6 billion. Additionally, the William J. Rutter Center, designed along with the adjacent 600-space parking structure by Ricardo Legorreta , opened in October 2005 and contains

4902-526: The Compton's Transgender Cultural District commemorating the historic transgender population and culture and in particular, the 1966 transgender and queer uprising, and the Compton's Cafeteria riot . Nestled near the downtown area, the Tenderloin has historically resisted gentrification , maintaining a seedy character and reputation for crime. Squalid conditions, homelessness, crime, illegal drug trade , prostitution , liquor stores , and strip clubs give

5031-518: The Cooper Medical College of the University of Pacific (founded 1858), entered a period of uncertainty in 1862 when its founder, Elias Samuel Cooper, died. In 1864, Toland founded a new medical school, Toland Medical College , and the faculty of Cooper Medical College chose to suspend operations and join the new school. The University of California was founded on March 23, 1868, with the enacting of its Organic Act. Section 8 of

5160-676: The Epic electronic health record , as a component of the $ 1+ billion adoption of this system across Sutter Health. In November 2014, Sutter Health announced further regional streamlining, where the West Bay Region was combined with the East Bay Region and the Peninsula Coastal Region to become one Sutter Health Bay Area operating unit. In 2013, CPMC began construction of a new $ 2.1 billion, 274-bed hospital on

5289-608: The Langley Porter Psychiatric Institute . In June 2020, UCSF paid $ 1.1 million (116 bitcoins) to the Netwalker criminal gang who had attacked their computer systems with malware and stole student data. The university negotiated with the gang after initially offering $ 780,000, which was rejected by the gang due to their perception of UCSF's wealth. USCF said in a statement to the BBC that they had "made

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5418-507: The Laurel Heights neighborhood. Initially intended for pharmacy school laboratory research and instruction, neighborhood concerns pushed the university to instead employ the building for academic desktop research, social and behavioral science departments, and administrative offices. On the western side of the city, the university acquired Mount Zion Hospital in 1990, which became the second major clinical site and since 1999 has hosted

5547-599: The Mission Bay campus in 1999. The development of a second campus in San Francisco was planned carefully and with business and community input. The Mission Bay neighborhood was occupied by old warehouses and rail yards. Initially, the campus consisted of 29.2 acres donated by the Catellus Development Corporation and 13.2 acres donated by the City and County of San Francisco. A later addition of

5676-678: The National Academy of Sciences , 69 members of the Institute of Medicine , and 30 members of the Academy of Arts and Sciences . UCSF graduate degrees include the Master of Science , Doctor of Philosophy, Doctor of Pharmacy , Doctor of Medicine , Doctor of Dental Surgery , and Doctor of Physical Therapy . USNWR graduate school rankings USNWR departmental rankings U.S. News & World Report ' s 2023–24 ranked

5805-872: The Nobel Prize in Physiology or Medicine . The 2010s saw increased construction and expansion at Mission Bay, with the Smith Cardiovascular Research Building, the UCSF Medical Center at Mission Bay, the Benioff Children's Hospital in 2010, the Sandler Neuroscience Center in 2012, Mission Hall and the Baker Cancer Hospital in 2013. The Children's Hospital was named after Marc Benioff , who donated $ 100 million toward

5934-465: The Osher Center for Integrative Medicine and outpatient resources. The San Francisco General Hospital campus cares for the indigent population of San Francisco and contains San Francisco's only Level I trauma center . The hospital itself is owned and operated by the City and County of San Francisco, but all of its doctors are UCSF faculty physicians and UCSF maintains research laboratories at

6063-593: The Tenderloin Reading Series , which is a quarterly literary event in the neighborhood as well as The Tender , a local journal focusing on the events, food, and politics of the neighborhood. In 2006, Gray Area Foundation for the Arts was formed to produce, exhibit, and develop creativity with the most contemporary new media technologies. Initially located on Taylor Street in an 8,000 sq ft (740 m ) space, they have since moved. In

6192-522: The UC Board of Regents designating the UCSF campus, rather than UC Berkeley , as the main site for all medical sciences of the UC system. The 20th century saw remarkable growth, with the expansion of new research institutes and facilities, which led to the administrative independence of UCSF and the selection of John B. de C.M. Saunders as the first Chancellor in 1964. Parnassus serves as the main campus of

6321-527: The UC Board of Regents to gain admission in 1873. Until 1906, the faculty of the medical school had provided care at the City-County Hospital (named San Francisco General Hospital from 1915 to 2016 and Zuckerberg San Francisco General Hospital and Trauma Center (SFGH) since 2016), but the medical school still did not have a teaching hospital of its own. Following the 1906 San Francisco earthquake , more than 40,000 people were relocated to

6450-650: The UCSF school of medicine as the fifth best medical school for research in the nation (tied with medical schools of Duke University , Stanford University , Vanderbilt University and Washington University in St. Louis ) and as the second best medical school for primary care. It is the only medical school to rank in the top five in both categories. In 2019, the Academic Ranking of World Universities , published annually by Shanghai Jiaotong University, ranked UCSF 1st in

6579-527: The Union Square shopping district to the northeast and the Civic Center office district to the southwest. Encompassing about 50 square blocks, it is historically bounded on the north by Geary Street, on the east by Mason Street, on the south by Market Street and on the west by Van Ness Avenue. The northern boundary with Lower Nob Hill has historically been set at Geary Boulevard . It contains

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6708-717: The Uptown Tenderloin Historic District . The terms "Tenderloin Heights" and " Tendernob " refer to the area around the boundary between the Upper Tenderloin and Lower Nob Hill. The eastern extent, near Union Square, overlaps with the Theater District . Part of the western extent of the Tenderloin, Larkin and Hyde Streets between Turk and O'Farrell, was officially named " Little Saigon " by the City of San Francisco. The area has

6837-433: The hard boiled detective fiction of Dashiell Hammett , who lived at 891 Post Street, the apartment he gave to Sam Spade in The Maltese Falcon . Also around this time, due to Red Light Abatement Act , prostitution and other vice began to be pushed out from the Barbary Coast district to the more southern and less business-occupied Tenderloin. In the mid-20th century, the Tenderloin provided work for many musicians in

6966-472: The understanding of the mechanisms of biology, analyzing the social, cultural, and historical determinants of health, alleviating human disease, reducing health disparities, and advancing health worldwide. U.S. News & World Report . In 2018, UCSF graduate programs ranked 1st in immunology and molecular biology , 3rd in neuroscience , 4th in cell biology and biochemistry , fifth in biochemistry / biophysics / structural biology . The School of Nursing

7095-438: The '70s and '80s for rehabilitation spaces for drug addicts and the still-ostracized gay community . Additionally, Tenderloin is zoned to prevent the construction of high-rises , and most of its buildings are protected historical properties. As such there has not been a concerted effort to revitalize Tenderloin, allowing it to retain its high crime rates and low property values. In the mid-2010s, upwards of 10,000 employees in

7224-419: The 1970s. As a result, a number of parks and playgrounds were created including first Boeddeker Park, a multi-use facility, then the youth-oriented Tenderloin Playground, followed by a number of mini-playgrounds. Boeddeker Park, located at the corner of Eddy and Jones Streets, is one of the most used parks per square foot in the city. It underwent a renovation, completed in December 2014, which has revitalized

7353-456: The 225-bed UC Hospital (1917), the Clinics Building (1934), the Langley Porter Clinic (1942) and the Herbert C. Moffitt Hospital (1955). In 1958, the addition of the Guy S. Millberry Union offered dorms and services for students. With medical education again concentrated in San Francisco, the UC Medical Center gained more independence and autonomy from the Berkeley campus during the 1960s. The four departments were renamed as "School of ..." and

7482-473: The Affiliated Colleges agreed to submit to the Regents' governance during the term of President Benjamin Ide Wheeler , as the Board of Regents had come to recognize the problems inherent in the existence of independent entities that shared the UC brand but over which UC had no real control. The last of the Affiliated Colleges to become an integral part of the university was the pharmacy school, in 1934. The schools continued to grow in numbers and reputation in

7611-441: The Bridges curriculum, more than half of which is dedicated to diagnostic reasoning. In 2017, 8,078 people applied and 505 were interviewed for 145 positions in the entering class. The Graduate Division, established in 1961, is home to 1,600 students enrolled in 31 degree programs (both PhD and Masters) and 1,100 postdoctoral scholars. Programs are based basic, translational, clinical, social, and population sciences, and focus on

7740-428: The Dental Clinics Building (1980), the new Joseph M. Long Hospital in 1983 (which was integrated with the existing Moffitt Hospital), the Beckman Vision Center and the Koret Vision Research Laboratory (1988), and the Kalmanovitz Library (1990). Due to the space constraints of the Parnassus Heights campus, UCSF started looking into expanding into other areas of the city. The university opened UCSF Laurel Heights in 1985 in

7869-399: The Graduate Division was founded in 1961. Further along this line, in 1964 the institution obtained full administrative independence under the name University of California, San Francisco Medical Center , becoming the ninth campus in the University of California system and the only one devoted exclusively to the health sciences. The first Chancellor under the new independent configuration

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7998-528: The Hand, and Transplant Hepatology. It also offers other accredited fellowships (non-ACGME) in MRI, Neurocritical care, Microsurgery, Oculoplastic Surgery, Retina Surgery, Transplant Nephrology, and Shoulder/Upper Extremity Surgery. Medical students from UCSF rotate through CPMC in their obstetrics/gynecology and surgery third year clerkships. In 2008, CPMC announced its new educational affiliation and partnership with Dartmouth Medical School to bring students to San Francisco for third- and fourth-year clerkships in

8127-436: The Helen Diller Family Cancer Research Building, opened in June 2009. Two additional research buildings designated for neuroscience and cardiovascular research are currently in the planning and design phase. A new specialty hospital focused on women, children, and cancer on the Mission Bay campus opened in February 2015. The Mount Zion Campus contains UCSF's NCI-designated Comprehensive Cancer Center, its Women's Health Center,

8256-514: The Organic Act authorized the Board of Regents to affiliate the University of California with independent self-sustaining professional colleges. In 1870, Toland Medical School began to negotiate an affiliation with the new public university. Meanwhile, some faculty of Toland Medical School elected to reopen the Medical Department of the University of the Pacific, which would later become Stanford University School of Medicine . Negotiations between Toland and UC were complicated by Toland's demand that

8385-401: The Public Library, Hospitality House, the Faithful Fools and other locations in the neighborhood. Tender Leaves, the center's literary journal was published from 1987 to 2006. From 2006 to 2009, The Loin's Mouth – conceived by its editor Rachel M. – was a semi-quarterly publication about life in the Tenderloin and Tendernob areas. Since then, others have come about to fill the gap including

8514-404: The San Francisco Bay Area. UCSF faculty have treated patients and trained residents since 1873 at the San Francisco General Hospital and for over 50 years at the San Francisco VA Medical Center . The University of California, San Francisco traces its history to Hugh Toland , a South Carolina surgeon who found great success and wealth after moving to San Francisco in 1852. A previous school,

8643-476: The San Francisco Bay area during this period. Herbert Boyer, a Professor of UCSF's biochemistry and biophysics department co-founded Genentech, the first therapeutic biotech firm, and UCSF scientists were also involved in the formation of most other major biotech firms in the San Francisco region that date back to the late 1970s and early 1980s. Furthermore, a 2006 analysis of the roots of the ten largest biotech firms measured in terms of their market capitalization in

8772-419: The San Francisco City Academy, was the first K-8 school in the Tenderloin District; founded in 1997. These all provide meals and other social services to poor and homeless residents and others. Glide and the surrounding neighborhood provided much of the setting for the 2006 film The Pursuit of Happyness . In 2008, The Salvation Army opened the Ray and Joan Kroc Community Center, a multipurpose center featuring

8901-464: The San Francisco Fringe Festival, the New Conservatory Theater, the Phoenix Theater, CounterPulse, PianoFight, the New Music Center and others. Alternate galleries include The Luggage Store, the 509 Cultural Center, and others. The neighborhood had many bars dating to prohibition and before with dive bars , including some left over from when the neighborhood housed large numbers of merchant seamen but most of those have closed or been transformed. One bar

9030-477: The San Francisco region highlighted the central position of UCSF continued to play within the region's industry: six biotech firms out of the top ten were either directly or indirectly linked to UCSF—a direct link meaning that the firm was founded by a UCSF scientist, an indirect link meaning that the firm was spun-off from a firm founded by a UCSF scientist. On the clinical side, great advances in patient care, diagnostics, and treatments advanced UCSF's reputation in

9159-423: The Spaniards' El Camino Real , which in turn traced an ancient north–south Native American trail. The Tenderloin is sheltered by Nob Hill , and far enough from the bay to be on solid ground. There is evidence that a community resided here several thousand years ago. In the early 1970s, the area along Market Street was excavated to develop the BART / MUNI subway station at Civic Center . The Tenderloin has been

9288-581: The Tay-Bush Inn , a café frequently visited by gay and lesbian patrons. As a response to police harassment, S.F. bar owners formed the San Francisco Tavern Guild . A study into prostitution in the Tenderloin found that while trans women face discrimination from certain professions and their sexual partners, sex workers in the Tenderloin area were adept at overcoming some such difficulties. On New Year's Day in 1965, police raided

9417-499: The Tenderloin Housing Clinic. On January 31, 2014, parking was banned on both sides of the street in an effort to reduce violence and drug activity. Without parked cars to hide illegal activity, there were fewer loiterers, and a decrease in drug activity. According to The New York Times , streets in the Tenderloin are littered with thousands of discarded heroin needles, and the sidewalks "have come to resemble

9546-610: The Tenderloin Senior Outreach Project ) was initiated when local university staff realized that many seniors felt afraid of crime, rent increases, and inadequate income. They facilitate interpersonal communication through coffee & refreshments, and groups of elderly people were encouraged to meet each other. Larkin Street Youth Services is a non-profit organization that offers a continuum of services that inspires youth to move beyond

9675-619: The Tenderloin community. The founder and director of CTI, Mary Ann Finch, began offering services here in 1997, after being inspired by her volunteer work with Mother Teresa in India. Religious institutions providing community services to the Tenderloin include Glide Memorial Church , which was reinvigorated by Cecil Williams in 1963, St. Anthony's , a program of the Franciscans and San Francisco City Impact founded in 1984 by Pastor Roger Huang. San Francisco City Impact's K-8 private school,

9804-585: The Tenderloin district are at risk of serious emotional and psychological problems arising from past traumatic experiences. Lack of appropriately targeted options available in the area has meant many youths will have few viable paths to deal effectively with their problems. The Tenderloin Housing Clinic has offered important social services to the poor of this neighborhood for decades. The Care Through Touch Institute, located between Hyde and Leavenworth Streets, offers free seated massage therapy to clients in

9933-505: The Tenderloin has had a number of strip clubs , although their number has decreased in recent decades. The best known was the Mitchell Brothers O'Farrell Theatre . The Tenderloin is also a hub for the gender diverse community. The categories of LGBTIQ created a new gender politics that helped to distinguish between the different groups; the Tenderloin was heavily populated by the transgender community. Many street activists paved

10062-617: The Tenderloin historically housed single adults and couples. After World War II, with the decline in central cities throughout the United States, the Tenderloin lost population, creating a large number of vacant housing units by the mid-1970s. Beginning in the late 1970s, after the Vietnam War , the Tenderloin received large numbers of refugees from Southeast Asia—first ethnic Chinese from Vietnam , then Khmer from Cambodia and Hmong from Laos . The low-cost vacant housing, and

10191-525: The Tenderloin to appropriately address the multifaceted needs of this diverse population, as well as offering support. In their study, Sausa, Keatley, Operario (2007) concluded that sex work for transgender women of color must be viewed as a forced consequence of structural barriers that they face, as well as an informed choice for survival as a result of these barriers. The Tenderloin Senior Organizing Project (TSOP; formerly known as

10320-634: The University of California designated the Parnassus campus as the UC Medical Center in San Francisco . After the medical facilities were updated and expanded, the preclinical departments returned to San Francisco in 1958, and from that point forward the M.D. degree program was again provided entirely in Parnassus Heights. During this period a number of research institutes were established, and many new facilities were added, such as

10449-476: The boundary was defined with borders different from today's. Some locations, such as Sam Spade 's apartment and John's Grill, also no longer lie in the Tenderloin because local economics and real estate have changed the character and labeling of areas over time. In July 2008, the area was designated as a historic district on the National Register of Historic Places . In 2017, a portion was declared

10578-464: The buildings in the neighborhood were destroyed by the 1906 earthquake and the backfires that were set by firefighters to contain the devastation. The area was immediately rebuilt with some hotels opening by 1907 and apartment buildings shortly thereafter, including the historic Cadillac Hotel. By the 1920s, the neighborhood was notorious for its gambling, billiard halls, boxing gyms, " speakeasies ", theaters, restaurants and other nightlife depicted in

10707-758: The city and South San Francisco. Among the related Institutes that are part of UCSF is the Philip R. Lee Institute for Health Policy Studies, founded in 1972 by Philip Randolph Lee. UCSF cooperates with the University of California College of the Law , a separate University of California institution located in San Francisco. This includes the formation of the UCSF/UC Law SF Consortium on Law, Science, and Health Policy. The program offers an LLM and MSL Degree program for health and science professionals. The Philip R. Lee Institute for Health Policy Studies

10836-505: The city's 98 homicides took place in the area in 2007. Seven of the top 10 violent crime plots (out of 665 in the entire city as measured by the San Francisco Police Department) are adjacent plots in the Tenderloin and Sixth and Market area. The first block of Turk Street, between Taylor and Mason, had one of the highest rates of violence and drug activity in San Francisco, according to a survey conducted by

10965-503: The city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. In 2023, UCSF received the 2nd highest research funding from the National Institutes of Health . In 2021, the university spent $ 1.71 billion in research and development, the second most among institutions of higher education in the U.S. With 25,398 employees, UCSF is the second-largest public agency employer in

11094-402: The difficult decision to pay some portion of the ransom...to the individuals behind the malware attack in exchange for a tool to unlock the encrypted data and the return of the data they obtained. It would be a mistake to assume that all of the statements and claims made in the negotiations are factually accurate". In 2021 the UCSF teamed up with Thermo Fisher Scientific on the construction of

11223-467: The disciplines of Internal Medicine, Psychiatry, Obstetrics and Gynecology, Family Medicine, Pediatrics and Neurology. In 2024, CPMC was recognized by US News and World Report as high performing in 11 common procedures and conditions, including colon and gynecologic cancer surgery, heart attack/failure, diabetes, kidney failure, stroke, and pneumonia. The hospital was also one of 50 programs nationally ranked in gastroenterology and gastrointestinal surgery by

11352-430: The district's residents that there would be a concerted Gentrification of Tenderloin, seeing an influx of affluent individuals move to the district, resulting in a spike in prices that would cause the neighborhood to no longer be viable for its current residents. However, Tenderloin residents have taken steps to prevent this, namely due to most of the district being owned by non-profit SROs , most of which were built in

11481-458: The end of the 19th Century interest in bringing them together grew. To make this possible, San Francisco Mayor Adolph Sutro donated 13 acres in Parnassus Heights at the base of Mount Parnassus (now known as Mount Sutro ). The new site, overlooking Golden Gate Park , opened in the fall of 1898, with the construction of the new Affiliated Colleges buildings. The school's first female student, Lucy Wanzer , graduated in 1876, after having to appeal to

11610-470: The first comprehensive cancer center in Northern California. Under the chancellorship of Joseph B. Martin , UCSF attempted a short-lived merger of its health system with Stanford Health and laid the groundwork for the expansion into Mission Bay. A pivotal moment in UCSF history was the deal between Vice Chancellor Bruce Spaulding and San Francisco Mayor Willie Brown for the development of

11739-809: The first pharmacy school in the West, established in 1872 by the California Pharmaceutical Society. The Pharmacy College was affiliated in June 1873, and together the Medical College and the Pharmacy College came to be known as the "Affiliated Colleges". The third college, the College of Dentistry, was established in 1881. Initially, the three Affiliated Colleges were located at different sites around San Francisco, but near

11868-599: The following years. One notable event was the incorporation of the Hooper Foundation for Medical Research in 1914, a medical research institute second only to the Rockefeller Institute . This addition bolstered the prestige of the Parnassus site during the long-running dispute over whether the schools should consolidate at Parnassus or in Berkeley. The final decision came in 1949 when the Regents of

11997-572: The health field. 1975 also saw the opening of the UCSF Center in Fresno . Julius R. Krevans, the fifth Chancellor from 1982 to 1993, was a strong advocate of biomedical research and public policy in the health sciences. During his tenure, UCSF rose to become one of the leading recipients of NIH funding. This led to the need for new space, and additions included the Marilyn Reed Lucia Child Care Center in 1978,

12126-805: The hospital campus. The earliest cases of HIV/AIDS were discovered at San Francisco General Hospital in the 1980s. To this day SF General Hospital has one of the world's leading HIV/AIDS treatment and research centers. UCSF is also affiliated with the San Francisco VA Medical Center and the J. David Gladstone Institutes , a private biomedical research entity that has recently moved to a new building adjacent to UCSF's Mission Bay campus. Since 2014, there has also been an affiliation with UCSF Benioff Children's Hospital Oakland (formerly Children's Hospital & Research Center Oakland). UCSF has its own police department, which serves its two major campuses as well as all satellite sites within

12255-403: The implementation of a new public-private initiative, Operation Leadership, which aims to help strengthen existing street cleaning and beautification services. As transgender women often face barriers such as discrimination and stigma when accessing health care, and show reluctance to disclose their gender when seeking health related services, a collaborative project named 'TRANS' was set up near

12384-477: The institution was renamed to its current form, the University of California, San Francisco (UCSF) , a symbol of its coequal status as a UC campus and a research university, while the Medical Center name was kept for its hospital facilities. Lee also was crucial in guiding UCSF through the turmoil of the late 1960s and worked to increase minority recruitment and enrollment. By then, UCSF had already reached

12513-481: The intersection of 6th Street, Market, Taylor and Golden Gate Avenue. In 1989 the Tenderloin Reflection and Education Center (TREC) spun off from St Anthony foundation and operated a cultural center including dance, music, writing quilting, and other arts workshops in the St. Boniface Neighborhood Center. TREC and its publishing project Freedom Voices continue to offer workshops on an occasional basis at

12642-407: The medical center were split between Parnassus and UC Berkeley , and discussions arose about which site should become the center of medical activity. In 1914, the Hooper Foundation for Medical Research decided to move its research work to the Parnassus site, becoming the first medical research foundation in the United States to be incorporated into a university. This expansion led to a 1949 decision by

12771-522: The medical school continue to bear his name, an issue on which he finally conceded. In March 1873, the trustees of Toland Medical College transferred it to the Regents of the University of California , and it became The Medical Department of the University of California . At the same time, the University of California also negotiated the incorporation of the California College of Pharmacy ,

12900-691: The neighborhood a seedy reputation. Part of the neighborhood forms part of the theater district. Prominent theatres include the Geary, the home of the American Conservatory Theater , and the Curran , Golden Gate and Orpheum Theatres operated by the Shorenstein Nederlander Organization . Alternative theaters in the Tenderloin include EXIT Theatre, which operates four storefront theaters and produces

13029-620: The neighborhood's theaters, hotels, burlesque houses, bars and clubs and was the location of the Musician's Union Building on Jones Street. The most famous jazz club was the Black Hawk at Hyde and Turk Streets where Dave Brubeck , Miles Davis , Thelonious Monk , Gerry Mulligan , and other jazz musicians recorded live albums for Fantasy Records in the late 1950s and early 1960s. With housing consisting almost entirely of single-room-occupancy hotel rooms, studio and one bedroom apartments,

13158-597: The neighborhood. 37°47′N 122°25′W  /  37.783°N 122.417°W  / 37.783; -122.417 University of California, San Francisco The University of California, San Francisco ( UCSF ), is a public land-grant research university in San Francisco , California , United States. It is part of the University of California system and is dedicated entirely to health science and life science . It conducts research and teaching in medical and biological sciences. UCSF

13287-461: The neighborhood. Dealing and use of illicit drugs occurs on the streets. Property crimes are common, especially theft from parked vehicles. Violent acts occur more often here and are generally related to drugs. The area was the scene of escalating drug violence in 2007, including brazen daylight shootings, as local gangs from San Francisco, and others from around the Bay Area battle for turf. 14 of

13416-977: The new company was organizing capitalization for replacement of every hospital facility, to conform to new seismic legislation underway in the California Legislature. In 1997, the former Franklin Hospital (then known as Ralph K. Davies Medical Center) was acquired by CPMC and became its third campus. This action was motivated in part by the since-failed merger of area teaching giants Stanford Hospital and UCSF Medical Center. In 2007, St. Luke's Hospital joined CPMC as its fourth campus. St. Luke's had joined Sutter as an independent affiliate in July 2001, after initiating and pursuing anti-trust litigation against CPMC. In 2010, Sutter Health reorganized its hospitals and medical foundations into five regions. In 2013, CPMC and its West Bay Region partners began to implement

13545-538: The new facility. In 2011, expansion also resumed at the Parnassus campus, with the construction of the Regeneration Medicine Building, a $ 123 million construction designed by New York architect Rafael Viñoly . The Stem Cell Center was named in honor of Eli Broad , who donated $ 25 million to the cause of research for diabetes, cardiovascular disease, Parkinson's disease, HIV/AIDS, and cancer. In 2014, UCSF celebrated its 150th anniversary with

13674-630: The opening of the Mission Bernal Campus and the Van Ness Campus, CPMC ended inpatient hospital and emergency services at its original two campuses: Sutter Health CPMC has origins in several early San Francisco medical institutions, including: Several of these institutions operated nursing schools (Pacific Dispensary, St. Luke's, Lane Hospital), as well as outreach clinics (e.g., St. Luke's Neighborhood Clinic, founded in 1920) during portions of their history. In 1991, Presbyterian Hospital (at that time known as Pacific Presbyterian Medical Center) and Children's Hospital merged, medical staffs were combined, and

13803-492: The park. YMCA and the Boys and Girls Club occupy the clubhouse, providing programming for youth and seniors. "It's the hub of positive community togetherness", Tenderloin police Capt. Jason Cherniss said of the park. "It's not necessarily police, it's community. It's ripe for that now. We're all getting more connected and sharing information." The Tenderloin Children's Playground, on Ellis Street between Leavenworth and Hyde Streets,

13932-653: The past the local Vietnamese Community has hosted the Tết celebration of the Vietnamese Lunar New Year in the Little Saigon section of the Tenderloin. Historically, the downtown Tenderloin had no park between Union Square to the East and Civic Center Plaza to the West until a number of activists, who organized the city's Citizens Committee for Open Space, advocated for more open space in the Tenderloin in

14061-416: The present-day institution. The site was established along Parnassus Avenue in 1898 on land donated by Mayor Adolph Sutro . At the time, the site was in the remote and uninhabited western part of San Francisco, but its medical facilities became vital in saving lives when 40,000 people were hosted in the nearby Golden Gate Park after the 1906 earthquake . In the early 1900s, the medical research operations of

14190-649: The proximity to Chinatown through the Stockton Street Tunnel , made the area appealing to refugees and resettlement agencies. Studio apartments became home for families of four and five people and became what a local police officer called "vertical villages." The Tenderloin quickly increased from having just a few children to having over 3,500 and this population has remained. A number of neighborhood Southeast Asian restaurants, bánh mì coffee shops, ethnic grocery stores, video shops, and other stores opened at this time, which still exist. The Tenderloin has

14319-399: The publication, ranking 46th out of 4,855 hospitals. In December 2023, the obstetrics department received a high performance rating in maternity care as well. The LeapFrog Group scores for the campuses as of 2023 were: Tenderloin, San Francisco The Tenderloin is a neighborhood in downtown San Francisco , in the flatlands on the southern slope of Nob Hill , situated between

14448-418: The regents ultimately decided in favor of the research model. As part of a compromise designed to heal the UCSF community, Kerr and Board of Regents chair Edward W. Carter negotiated the simultaneous resignations of both Saunders and Dean William Reinhardt of the UCSF School of Medicine, who had been held responsible for the researchers' rebellion by Saunders' supporters. In 1966, Willard C. Fleming, DDS,

14577-540: The site of the former Jack Tar Hotel at Van Ness and Geary (once dubbed "the box Disneyland came in"). The new Van Ness Campus was to replace both the California Campus and Pacific Campus for inpatient care. Further, the new facility came with several patient safety focused innovations, and is the first known structure in North America to use viscous wall dampers designed to absorb strong seismic activity . Van Ness Campus officially opened on March 2, 2019. Ground

14706-569: The street. Services run the gamut from street outreach and temporary shelters to transitional living programs, health and wellness services, and comprehensive education and employment programs. In 1987, residents and others from the Aarti Hotel on Leavenworth Street founded the 509 Cultural Center at 509 Ellis Street. After the 1989 earthquake damaged that facility, artists founded the Luggage Store Gallery at 1007 Market, at

14835-423: The tech sector, such as Google and Yahoo! , moved into Tenderloin and Mid-Market neighborhoods to take advantage of the low rent and prices, resulting in significant community backlash. Community residents would protest Google employees going to work while some welcomed them and the redevelopment that comes with them. However, by 2018 these revitalization efforts would largely end due to a resurgence of crime, and

14964-732: The three institutions (together with Berkeley and Stanford ) that comprise the Biohub , which is housed on the Mission Bay campus. The project consists of a medical science research center funded by a $ 600 million commitment from Facebook CEO and founder Mark Zuckerberg and UCSF alumna pediatrician Priscilla Chan , his wife. In January 2017, UCSF announced a $ 500 million gift from the Helen Diller Foundation to increase financial aid for faculty and students, invest in cutting-edge research projects, and expand scholarships for dental, medical, nursing and pharmacy students. This gift

15093-478: The top ranks of US schools in the health sciences through its innovative programs that blended basic science, research, and clinical instruction. This stature was further augmented by Francis A. Sooy, fourth Chancellor, who dedicated his ten years to recruiting the top physicians and scientists in the field. The 1970s saw a dramatic expansion of UCSF, both in its medical capacities and as a research institute. The increase in researchers, physicians and students brought

15222-632: The treatment of melanoma. CPMC is a teaching site for residents in the UCSF General Surgery, Obstetrics and Gynecology, Orthopedic Surgery, and Pediatrics programs. CPMC itself hosts residencies in Internal Medicine, Ophthalmology, and Psychiatry. In addition to these residency programs, it offers ACGME accredited fellowship positions in Cardiology, Gastroenterology, Pulmonology/Critical Care, Endocrinology, Plastic Surgery of

15351-663: The university and includes administration offices, numerous research labs, the 600-bed UCSF Medical Center , the Langley Porter Psychiatric Institute , the Mulberry Student Union, and the UCSF Library . Additionally, the Schools of Dentistry, Pharmacy, Medicine, Nursing are also located at Parnassus. It also houses the UCSF neurology outpatient practice that serves as a referral center for most of northern California and Reno, Nevada . UCSF's Beckman Vision Center

15480-521: The way for change, such as Anne Ogborn . In his seminar 'Take Charge of Your Life', Jim Rohn recounted his visits to the Tenderloin to experience the "human tragedy". He described his visit to a bar in the Tenderloin where the bar tender told him about a dancer by the name of Cookie, who was severely crippled and had a child suffering from leukemia. The Tenderloin is a high-crime neighborhood, particularly violent street crime such as robbery and aggravated assault. Graffiti art and tagging are common in

15609-670: The world for Clinical Medicine and 2nd in the world for Pharmacy. Among U.S. medical schools, UCSF is ranked 3rd for research and ranked 2nd for clinical training in the primary care specialties (internal medicine, family medicine, and pediatrics) by U.S. News & World Report . The UCSF Medical Center is rated as the 12th best hospital in the US and 3rd best in California (behind Cedars-Sinai Medical Center and UCLA Medical Center , which are both located in Los Angeles) according to

15738-439: Was John B. de C.M. Saunders, previously Provost, a White South African who had a strong preference for clinical medical training over research. The resulting controversy "became front-page news in San Francisco". On one side was most of the clinical faculty, who owed their appointments to Saunders. On the other side was the basic sciences faculty, many of whom were recent transplants from Berkeley. UC President Clark Kerr and

15867-660: Was broken in September 2014 to build a 120-bed replacement hospital at St. Luke's, after years of dispute over whether CPMC would continue to operate a hospital in the Mission District. Mission Bernal Campus officially opened ahead of schedule on August 25, 2018. This new facility has maternity services staffed by certified nurse midwives and physicians that is on California's Maternity Care Honor roll, specialized acute elderly care unit, and an emergency department with Geriatric Emergency Department Accreditation (GED). As

15996-587: Was established in 1907, following the 1906 San Francisco earthquake , which lead to UCSF becoming active in providing health care in San Francisco. It is recognized as one of the premier nursing schools in the United States. In the U.S. News & World Report for 2016, the UCSF School of Nursing tied for 2nd overall in the nation. UCSF also ranked in the top 10 in all six of its rated nursing specialties, including ranking #1 for its psychiatric / mental health nurse practitioner program, and ranking #2 for its family nurse practitioner program. Previously, in 2012,

16125-630: Was founded as Toland Medical College in 1864. In 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout

16254-417: Was named UCSF's second Chancellor. Fleming brought balance between clinicians and researchers and a new level of stability to the administration. By the end of the 1960s, the university was starting to become a leading research center; its research enterprise was bolstered by the opening of Health Sciences East and Health Sciences West the same year. Under the guidance of the third Chancellor, Philip R. Lee ,

16383-455: Was opened in 1995 and has attractive indoor and outdoor recreational facilities and hosts a number of community and family events. Sgt. John Macaulay Park, named after a San Francisco police officer who was killed in the adjacent alley while on duty, is a small gated playground at the corner of O'Farrell and Larkin Streets. Although the park is located across the street from a strip club, it

16512-523: Was operational on the first floor of the medical building, and by April 1907, the new teaching hospital started to admit inpatients. This created the need to train nursing students, of whom the first was informally admitted in June; in December 1907, the UC Training School for Nurses was formally established, adding a fourth professional school to the Affiliated Colleges. Around this time,

16641-490: Was overheard saying that when he was assigned to another part of the city, he could only afford to eat chuck steak on the salary he was earning, but after he was transferred to this neighborhood he was making so much money on the side soliciting bribes that now he could afford to eat tenderloin ( ' filet mignon ' ) instead. The Tenderloin borders the Mission/Market Street corridor, which follows

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