Bad Parents is a 2012 comedy film written and directed by Caytha Jentis and starring Janeane Garofalo . The movie humorously showcases New Jersey soccer moms becoming obsessed with their children's role in the sport. The supporting cast features Christopher Titus and Cheri Oteri .
127-551: The film was shot entirely in New Jersey and used local Morris County talent. Jentis based the film on her own experiences. Bad Parents premiered on October 3, 2012, at the Montclair Film Festival and later played at Ridgewood, New Jersey , on February 23, 2014. This film article about a 2010s comedy film is a stub . You can help Misplaced Pages by expanding it . New Jersey New Jersey
254-491: A herbicide ), reduction of spoilage, or improving the nutrient profile of the crop. Examples in non-food crops include production of pharmaceutical agents , biofuels , and other industrially useful goods, as well as for bioremediation . Farmers have widely adopted GM technology. Between 1996 and 2011, the total surface area of land cultivated with GM crops had increased by a factor of 94, from 17,000 to 1,600,000 square kilometers (4,200,000 to 395,400,000 acres). 10% of
381-474: A plasmid vector inserted into the bacterium Escherichia coli . Insulin, widely used for the treatment of diabetes, was previously extracted from the pancreas of abattoir animals (cattle or pigs). The genetically engineered bacteria are able to produce large quantities of synthetic human insulin at relatively low cost. Biotechnology has also enabled emerging therapeutics like gene therapy . The application of biotechnology to basic science (for example through
508-698: A Unified Database System) database is intended to help companies, interested private users and competent authorities to find precise information on the presence, detection and identification of GMOs used in the European Union . The information is provided in English. In 1988, after prompting from the United States Congress , the National Institute of General Medical Sciences ( National Institutes of Health ) (NIGMS) instituted
635-461: A bacterium (of the genus Pseudomonas ) capable of breaking down crude oil, which he proposed to use in treating oil spills. (Chakrabarty's work did not involve gene manipulation but rather the transfer of entire organelles between strains of the Pseudomonas bacterium). The MOSFET invented at Bell Labs between 1955 and 1960, Two years later, Leland C. Clark and Champ Lyons invented
762-414: A bill interpreting the constitution to mean universal white male suffrage , excluding paupers; the constitution was itself an act of the legislature and not enshrined as the modern constitution. On February 15, 1804, New Jersey became the last northern state to abolish new slavery and enacted legislation that slowly phased out existing slavery. This led to a gradual decrease of the slave population. By
889-438: A child's parentage (genetic mother and father) or in general a person's ancestry . In addition to studying chromosomes to the level of individual genes, genetic testing in a broader sense includes biochemical tests for the possible presence of genetic diseases, or mutant forms of genes associated with increased risk of developing genetic disorders. Genetic testing identifies changes in chromosomes , genes, or proteins. Most of
1016-413: A consortium could be used as industrial microbes to produce precursors of the chemotherapeutic agent paclitaxel by applying the metabolic engineering in a co-culture approach to exploit the benefits from the two microbes. Another example of synthetic biology applications in industrial biotechnology is the re-engineering of the metabolic pathways of E. coli by CRISPR and CRISPRi systems toward
1143-422: A drug's efficacy or toxicity . The purpose of pharmacogenomics is to develop rational means to optimize drug therapy, with respect to the patients' genotype , to ensure maximum efficacy with minimal adverse effects . Such approaches promise the advent of " personalized medicine "; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Biotechnology has contributed to
1270-410: A food source into another form. Before the time of Charles Darwin 's work and life, animal and plant scientists had already used selective breeding. Darwin added to that body of work with his scientific observations about the ability of science to change species. These accounts contributed to Darwin's theory of natural selection. For thousands of years, humans have used selective breeding to improve
1397-417: A funding mechanism for biotechnology training. Universities nationwide compete for these funds to establish Biotechnology Training Programs (BTPs). Each successful application is generally funded for five years then must be competitively renewed. Graduate students in turn compete for acceptance into a BTP; if accepted, then stipend, tuition and health insurance support are provided for two or three years during
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#17327977123291524-536: A harmful microbe are examples of environmental implications of biotechnology. Many cities have installed CityTrees , which use biotechnology to filter pollutants from urban atmospheres. The regulation of genetic engineering concerns approaches taken by governments to assess and manage the risks associated with the use of genetic engineering technology, and the development and release of genetically modified organisms (GMO), including genetically modified crops and genetically modified fish . There are differences in
1651-517: A higher proportion of immigrants. New Jersey is home to roughly half a million unauthorized immigrants , comprising an estimated 6.2% of the population, which in 2018 was the fifth-highest percentage of any U.S. state. The municipalities of Camden, Jersey City, and Newark are considered sanctuary cities for illegal immigrants. For further information on various ethnoracial groups and neighborhoods prominently featured within New Jersey, see
1778-794: A large and diverse population. New Jersey was among the Thirteen Colonies that supported the American Revolution , hosting several pivotal battles and military commands in the American Revolutionary War . New Jersey remained in the Union during the American Civil War and provided troops, resources, and military leaders in support of the Union Army . After the war, the state emerged as
1905-547: A major manufacturing center and a leading destination for immigrants, helping drive the Industrial Revolution in the U.S. New Jersey was the site of many industrial, technological, and commercial innovations . Many prominent Americans associated with New Jersey have proven influential nationally and globally, including in academia, advocacy, business, entertainment, government, military, non-profit leadership, and other fields. New Jersey's central location in
2032-417: A major destination for immigrants and is home to one of the world's most multicultural populations . Echoing historical trends, the state has increasingly re-urbanized, with growth in cities outpacing suburbs since 2008. New Jersey is one of the most educated, affluent, healthy, diverse and highly developed states in the U.S., ranking it high in several quality of life metrics. As of 2022, New Jersey had
2159-799: A major industry, especially the Sterling Hill Mine . New Jersey prospered through the Roaring Twenties . The first Miss America Pageant was held in 1921 in Atlantic City ; the Holland Tunnel connecting Jersey City to Manhattan opened in 1927; and the first drive-in movie was shown in 1933 in Camden . During the Great Depression of the 1930s, the state offered begging licenses to unemployed residents,
2286-518: A million residents commute daily into the city for work, many via public transportation. The Jersey Shore , along the Atlantic Coast in Central and South Jersey, has its own unique natural, residential, and cultural characteristics owing to its location by the ocean. South Jersey represents the southernmost geographical region of the northeastern United States . The Delaware Valley includes
2413-772: A motor torpedo boat commanded by Lt. (j.g.) John F. Kennedy in World War II, was built at the Elco Boatworks in Bayonne . The aircraft carrier USS Enterprise (CV-6) was briefly docked at the Military Ocean Terminal in Bayonne in the 1950s before she was sent to Kearney to be scrapped. In 1962, the world's first nuclear-powered cargo ship, the NS Savannah , was launched at Camden. In 1951,
2540-499: A native Philadelphian, had New Jersey ties and formally resided in New Jersey at the time; he later became Governor of New Jersey (1878–81). (In New Jersey, the factions of the Democratic party managed an effective coalition in 1860.) During the American Civil War , the state was led first by Republican governor Charles Smith Olden , then by Democrat Joel Parker . During the course of the war, between 65,000 and 80,000 soldiers from
2667-415: A notable advance in comparison with the lack of studies published in recent years in scientific journals by those companies. Krimsky, Sheldon (2015). "An Illusory Consensus behind GMO Health Assessment". Science, Technology, & Human Values . 40 (6): 883–914. doi : 10.1177/0162243915598381 . S2CID 40855100 . I began this article with the testimonials from respected scientists that there
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#17327977123292794-513: A number of articles some of which have strongly and negatively influenced the public opinion on GM crops and even provoked political actions, such as GMO embargo, share common flaws in the statistical evaluation of the data. Having accounted for these flaws, we conclude that the data presented in these articles does not provide any substantial evidence of GMO harm. The presented articles suggesting possible harm of GMOs received high public attention. However, despite their claims, they actually weaken
2921-434: A number of ecological benefits, if not used in excess. Insect-resistant crops have proven to lower pesticide usage, therefore reducing the environmental impact of pesticides as a whole. However, opponents have objected to GM crops per se on several grounds, including environmental concerns, whether food produced from GM crops is safe, whether GM crops are needed to address the world's food needs, and economic concerns raised by
3048-602: A promising method to combat malnutrition in India and other countries. Industrial biotechnology (known mainly in Europe as white biotechnology) is the application of biotechnology for industrial purposes, including industrial fermentation . It includes the practice of using cells such as microorganisms , or components of cells like enzymes , to generate industrially useful products in sectors such as chemicals, food and feed, detergents, paper and pulp, textiles and biofuels . In
3175-478: A pure microbiological culture in an industrial process, that of manufacturing corn starch using Clostridium acetobutylicum , to produce acetone , which the United Kingdom desperately needed to manufacture explosives during World War I . Biotechnology has also led to the development of antibiotics. In 1928, Alexander Fleming discovered the mold Penicillium . His work led to the purification of
3302-414: A wide range of procedures for modifying living organisms for human purposes, going back to domestication of animals, cultivation of plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization . Modern usage also includes genetic engineering, as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as
3429-720: Is Kitty Ann Mountain in Morris County , rising 892 feet (272 m). The Palisades are a line of steep cliffs on the west side of the Hudson River in Bergen and Hudson Counties . Major New Jersey rivers include the Hudson , Delaware , Raritan , Passaic , Hackensack , Rahway , Musconetcong , Mullica , Rancocas , Manasquan , Maurice , and Toms rivers. Due to New Jersey's peninsular geography, both sunrise and sunset are visible over water from different points on
3556-448: Is genetic engineering , which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create new traits or modifying existing ones. Other important techniques used in biotechnology include tissue culture, which allows researchers to grow cells and tissues in the lab for research and medical purposes, and fermentation , which
3683-767: Is a state in both the Mid-Atlantic and Northeastern regions of the United States. It is the most densely populated state and at the center of the Northeast megalopolis . New Jersey is bordered to the northeast by New York state ; on its east, southeast, and south by the Atlantic Ocean ; on its west by the Delaware River and Pennsylvania ; and on its southwest by Delaware Bay and Delaware . At 7,354 square miles (19,050 km ), New Jersey
3810-507: Is a rapidly evolving field with significant potential to address pressing global challenges and improve the quality of life for people around the world; however, despite its numerous benefits, it also poses ethical and societal challenges, such as questions around genetic modification and intellectual property rights . As a result, there is ongoing debate and regulation surrounding the use and application of biotechnology in various industries and fields. The concept of biotechnology encompasses
3937-635: Is based on the basic biological sciences (e.g., molecular biology , biochemistry , cell biology , embryology , genetics , microbiology ) and conversely provides methods to support and perform basic research in biology. Biotechnology is the research and development in the laboratory using bioinformatics for exploration, extraction, exploitation, and production from any living organisms and any source of biomass by means of biochemical engineering where high value-added products could be planned (reproduced by biosynthesis , for example), forecasted, formulated, developed, manufactured, and marketed for
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4064-638: Is considered one of the essential cornerstones in industrial biotechnology due to its financial and sustainable contribution to the manufacturing sector. Jointly biotechnology and synthetic biology play a crucial role in generating cost-effective products with nature-friendly features by using bio-based production instead of fossil-based. Synthetic biology can be used to engineer model microorganisms , such as Escherichia coli , by genome editing tools to enhance their ability to produce bio-based products, such as bioproduction of medicines and biofuels . For instance, E. coli and Saccharomyces cerevisiae in
4191-865: Is expected to be good news for the biotechnology sector, with the Department of Energy estimating ethanol usage could reduce U.S. petroleum-derived fuel consumption by up to 30% by 2030. The biotechnology sector has allowed the U.S. farming industry to rapidly increase its supply of corn and soybeans—the main inputs into biofuels—by developing genetically modified seeds that resist pests and drought. By increasing farm productivity, biotechnology boosts biofuel production. Biotechnology has applications in four major industrial areas, including health care (medical), crop production and agriculture, non-food (industrial) uses of crops and other products (e.g., biodegradable plastics , vegetable oil , biofuels ), and environmental uses. For example, one application of biotechnology
4318-572: Is literally no scientific controversy over the health effects of GMOs. My investigation into the scientific literature tells another story. And contrast: Panchin, Alexander Y.; Tuzhikov, Alexander I. (January 14, 2016). "Published GMO studies find no evidence of harm when corrected for multiple comparisons". Critical Reviews in Biotechnology . 37 (2): 213–217. doi : 10.3109/07388551.2015.1130684 . ISSN 0738-8551 . PMID 26767435 . S2CID 11786594 . Here, we show that
4445-803: Is now New York Harbor and took control of Fort Amsterdam , annexing the entire province. During the English Civil War , the Channel Island of Jersey remained loyal to the British Crown and gave sanctuary to the King . In the Royal Square in St Helier , Charles II of England was proclaimed King in 1649, following the execution of his father, Charles I . North American lands were divided by Charles II , who gave his brother,
4572-600: Is part of the Pennsylvania-based Lehigh Valley metro area. The 21 counties in New Jersey, listed in order by population (as of the 2020 census) are: For its overall population and nation-leading population density, New Jersey has a relative paucity of classic large cities. This paradox is most pronounced in Bergen County , the state's most populous county, whose 955,732 residents at the 2020 census inhabited 70 municipalities, of which
4699-434: Is the fifth-smallest state in land area , but with close to 9.3 million residents as of the 2020 United States census , it ranks 11th in population . The state capital is Trenton , and the state's most populous city is Newark . New Jersey is the only U.S. state in which every county is deemed urban by the U.S. Census Bureau . New Jersey was first inhabited by Paleo-Indians as early as 13,000 B.C.E. The Lenape were
4826-673: Is the application of the principles of engineering and natural sciences to tissues, cells, and molecules. This can be considered as the use of knowledge from working with and manipulating biology to achieve a result that can improve functions in plants and animals. Relatedly, biomedical engineering is an overlapping field that often draws upon and applies biotechnology (by various definitions), especially in certain sub-fields of biomedical or chemical engineering such as tissue engineering , biopharmaceutical engineering , and genetic engineering . Although not normally what first comes to mind, many forms of human-derived agriculture clearly fit
4953-708: Is the directed use of microorganisms for the manufacture of organic products (examples include beer and milk products). Another example is using naturally present bacteria by the mining industry in bioleaching . Biotechnology is also used to recycle, treat waste, clean up sites contaminated by industrial activities ( bioremediation ), and also to produce biological weapons . A series of derived terms have been coined to identify several branches of biotechnology, for example: In medicine, modern biotechnology has many applications in areas such as pharmaceutical drug discoveries and production, pharmacogenomics , and genetic testing (or genetic screening ). In 2021, nearly 40% of
5080-442: Is used to produce a wide range of products such as beer, wine, and cheese. The applications of biotechnology are diverse and have led to the development of essential products like life-saving drugs, biofuels , genetically modified crops, and innovative materials. It has also been used to address environmental challenges, such as developing biodegradable plastics and using microorganisms to clean up contaminated sites. Biotechnology
5207-488: Is widely used in biomedical applications, such as the detection of DNA hybridization , biomarker detection from blood , antibody detection, glucose measurement, pH sensing, and genetic technology . By the mid-1980s, other BioFETs had been developed, including the gas sensor FET (GASFET), pressure sensor FET (PRESSFET), chemical field-effect transistor (ChemFET), reference ISFET (REFET), enzyme-modified FET (ENFET) and immunologically modified FET (IMFET). By
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5334-454: The 2010 U.S. census , which counted 8,791,894 residents. The state ranked eleventh in the country by total population and first in population density, with 1,185 residents per square mile (458 per km ). Historically, New Jersey has experienced one of the fastest growth rates in the country, with its population increasing by double digits almost every decade until 1980; growth has since slowed but remained relatively robust until recently. In 2022,
5461-406: The 2010 United States census , only four municipalities had over 100,000 residents (although Edison and Woodbridge Township came very close); this number increased to seven by the 2020 census. Residents of New Jersey are most commonly referred to as New Jerseyans or, less commonly, as New Jerseyites. According to the 2020 U.S. census , the state had a population of 9,288,994, a 5.7% increase since
5588-699: The American Civil War 's end, about a dozen African Americans in New Jersey were still held in bondage. New Jersey voters eventually ratified the constitutional amendments banning slavery and granting rights to the United States' black population. Industrialization accelerated in the present-day North Jersey region of the state following completion of the Morris Canal in 1831. The canal allowed for anthracite coal to be transported from eastern Pennsylvania 's Lehigh Valley to North Jersey's growing industries in Paterson , Newark , and Jersey City . In 1844,
5715-630: The American Revolutionary War , British and American armies crossed New Jersey numerous times, and several pivotal battles took place in the state. Because of this, New Jersey today is sometimes referred to as "The Crossroads of the American Revolution". The winter quarters of the Continental Army were established in New Jersey twice by General George Washington in Morristown , which has been called "The Military Capital of
5842-678: The Cape May County peninsula at the southeastern tip of New Jersey; in doing so, the Jersey Shore became readily accessible to millions of residents in the New York metropolitan area. In 1959, Air Defense Command deployed the CIM-10 Bomarc surface-to-air missile to McGuire Air Force Base . On June 7, 1960, an explosion in a CIM-10 Bomarc missile fuel tank caused an accident and subsequent plutonium contamination. In
5969-634: The DNA of which has been modified with genetic engineering techniques. In most cases, the main aim is to introduce a new trait that does not occur naturally in the species. Biotechnology firms can contribute to future food security by improving the nutrition and viability of urban agriculture. Furthermore, the protection of intellectual property rights encourages private sector investment in agrobiotechnology. Examples in food crops include resistance to certain pests, diseases, stressful environmental conditions, resistance to chemical treatments (e.g. resistance to
6096-456: The Dominion of New England from 1686 to 1689. In 1702, the two provinces were reunited under a royal governor rather than a proprietary one . Edward Hyde , titled Lord Cornbury, became the first governor of the royal colony. Britain believed that he was an ineffective and corrupt ruler, taking bribes and speculating on land. In 1708, he was recalled to England. New Jersey was then ruled by
6223-719: The Dutch in the early 17th century, and their primary relationship with the Dutch and later European settlers was through fur trade . The Dutch were the first Europeans to lay claim to lands in New Jersey. The Dutch colony of New Netherland consisted of parts of the modern Mid-Atlantic states. Although the European principle of land ownership was not recognized by the Lenape , Dutch West India Company policy required its colonists to purchase land that they settled. The first to do so
6350-470: The Human Genome Project ) has also dramatically improved our understanding of biology and as our scientific knowledge of normal and disease biology has increased, our ability to develop new medicines to treat previously untreatable diseases has increased as well. Genetic testing allows the genetic diagnosis of vulnerabilities to inherited diseases , and can also be used to determine
6477-585: The Lenape tribe . Scheyichbi is the Lenape name for the land that represents present-day New Jersey. The Lenape were several autonomous groups that practiced maize agriculture in order to supplement their hunting and gathering in the region surrounding the Delaware River , the lower Hudson River , and western Long Island Sound . The Lenape were divided into matrilineal clans that were based upon common female ancestors. Clans were organized into three distinct phratries identified by their animal sign: Turtle , Turkey , and Wolf . They first encountered
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#17327977123296604-805: The New Jersey Supreme Court to fund schools equitably, the New Jersey legislature passed an income tax bill in 1976. Prior to this bill, the state had no income tax. In the early part of the 2000s, two light rail systems were opened: the Hudson–Bergen Light Rail in Hudson County and the River Line between Camden and Trenton . The intent of these projects was to encourage transit-oriented development in North Jersey and South Jersey , respectively. The HBLR
6731-606: The New Jersey Turnpike opened, facilitating efficient travel by car and truck between North Jersey and metropolitan New York , and South Jersey and metropolitan Philadelphia . Subsequently, in 1957, the Garden State Parkway was completed, serving as a diagonal counterpart to the Turnpike, and opening up highway travel along New Jersey's coastal flank between Bergen County in the northeast and
6858-627: The North Atlantic Ocean . The pressure of collision between North America and Africa gave rise to the Appalachian Mountains . Around 18,000 years ago, the Ice Age resulted in glaciers that reached New Jersey. As glaciers retreated, they left behind Lake Passaic along with rivers, meadows , swamps, and gorges . Since the 6th millennium BC , Native American people have inhabited New Jersey, beginning with
6985-540: The Philippines . New Jersey is one of the most ethnically diverse states in the United States: as of 2022, over one-fifth (21.5%) of its residents are Hispanic or Latino, 15.3% are Black, and one-tenth are Asian. One in four New Jerseyans were born abroad and more than one million (12.1%) are not fully fluent in English. Compared to the U.S. as a whole, the state is more racially and ethnically diverse and has
7112-816: The Second Continental Congress declared American Independence from Great Britain . It was an act of the Provincial Congress , which made itself into the State Legislature . To reassure neutrals, it provided that it would become the legislature would disband if New Jersey reached reconciliation with Great Britain. Among the 56 Founding Fathers who signed the Declaration of Independence , five were New Jersey representatives: Richard Stockton , John Witherspoon , Francis Hopkinson , John Hart , and Abraham Clark . During
7239-605: The Skylands Region , is more wooded, rural, and mountainous. The chief tree of the northern forests is the oak . The New Jersey Pine Barrens is situated in the southern interior of New Jersey and covered extensively by mixed pine and oak forest; its population density is lower than most of the state. High Point in Montague Township , Sussex County is the state's highest elevation at 1,803 feet (550 m) above sea level. The state's highest prominence
7366-638: The 1950s, and by 2020 had rebounded to 311,549. New Jersey is located at the center of the Northeast megalopolis , the most populated American urban agglomeration . It is bordered on the north and northeast by New York (parts of which are across the Hudson River , Upper New York Bay , the Kill Van Kull , Newark Bay , and the Arthur Kill ); on the east by the Atlantic Ocean; on the southwest by Delaware across Delaware Bay ; and on
7493-638: The 1960s, race riots erupted in many of the industrial cities of North Jersey . The first race riots in New Jersey occurred in Jersey City on August 2, 1964. Several others ensued in 1967, in Newark and Plainfield . Other riots followed the assassination of Martin Luther King Jr. in April 1968, just as in the rest of the country. A riot occurred in Camden in 1971. As a result of an order from
7620-586: The 48 states. In addition, Fort Dix (1917) (originally called "Camp Dix"), Camp Merritt (1917), and Camp Kilmer (1941) were all constructed to house and train American soldiers through both World Wars. New Jersey also became a principal location for defense in the Cold War . Fourteen Nike missile stations were constructed for the defense of the New York City and Philadelphia areas. PT-109 ,
7747-751: The American Revolution." On the night of December 25–26, 1776, the Continental Army under George Washington crossed the Delaware River . After the crossing, they surprised and defeated the Hessian troops in the Battle of Trenton . Slightly more than a week after victory at Trenton , Continental Army forces gained an important victory by stopping General Cornwallis's charges at the Second Battle of Trenton . By evading Cornwallis's army,
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#17327977123297874-409: The British column by surprise. When the British army attempted to flank the Americans, the Continental Army retreated in disorder. Their ranks were later reorganized and withstood British charges. In the summer of 1783, the Continental Congress met in Nassau Hall at Princeton University , making Princeton the nation's capital for four months. It was there that the Continental Congress learned of
8001-422: The Census Bureau estimated there were 6,262 fewer residents than in 2020, a decline of 0.3% from 2020, related to the COVID-19 pandemic . New Jersey is the only state where every county is deemed urban as defined by the Census Bureau . Most residents live in the counties surrounding New York City , the nation's largest city, Philadelphia , the nation's sixth-largest city, or along the eastern Jersey Shore ;
8128-453: The Continental Army was able to make a surprise attack on Princeton and successfully defeated the British forces there on January 3, 1777. Emanuel Leutze 's painting of Washington Crossing the Delaware became an icon of the Revolution. Continental Army forces under Washington's command met British forces under General Henry Clinton at the Battle of Monmouth in an indecisive engagement in June 1778. Washington's forces attempted to take
8255-401: The Duke of York (later King James II ), the region between New England and Maryland as a proprietary colony (as opposed to a royal colony ). James then granted land between the Hudson River and the Delaware River (the land that would become New Jersey) to two friends who had remained loyal through the English Civil War : Sir George Carteret and Lord Berkeley of Stratton . The area
8382-410: The EU and approval for import and processing. While only a few GMOs have been approved for cultivation in the EU a number of GMOs have been approved for import and processing. The cultivation of GMOs has triggered a debate about the coexistence of GM and non-GM crops. Depending on the coexistence regulations, incentives for the cultivation of GM crops differ. The EUginius (European GMO Initiative for
8509-491: The Industrial Revolution, having been granted 1,093 patents , many of which for inventions he developed while working in New Jersey. Edison's facilities, first at Menlo Park and then in West Orange , are considered perhaps the first research centers in the United States. Christie Street in Menlo Park was the first thoroughfare in the world to have electric lighting. Transportation was greatly improved as locomotion and steamboats were introduced to New Jersey. Iron mining
8636-695: The Jersey Shore. The state consists of two climate zones; most of the state has a humid subtropical climate (Cfa), while the northwest has a humid continental climate (Dfa). New Jersey receives between 2,400 and 2,800 hours of sunshine annually. Summers are typically hot and humid, with statewide average high temperatures of 82–87 °F (28–31 °C) and lows of 60–69 °F (16–21 °C); however, temperatures exceed 90 °F (32 °C) on average 25 days each summer, exceeding 100 °F (38 °C) in some years. Winters are usually cold, with average high temperatures of 34–43 °F (1–6 °C) and lows of 16 to 28 °F (−9 to −2 °C) for most of
8763-431: The Northeast megalopolis helped fuel its rapid growth and suburbanization in the second half of the 20th century. Since the beginning of the 21st century, the state's economy has become highly diversified, with major sectors including biotechnology , pharmaceuticals , information technology , finance , and tourism , and it has become an Atlantic seaboard epicenter for logistics and distribution . New Jersey remains
8890-431: The U.S. National Oceanic and Atmospheric Administration have concluded that New Jersey has been the fastest-warming state by average air temperature over a 100-year period beginning in the early 20th century. The U.S. Census Bureau divides New Jersey's 21 counties into seven metropolitan statistical areas , with 20 counties included in either the New York City or Philadelphia Combined Statistical Area . Warren County
9017-518: The antibiotic compound formed by the mold by Howard Florey , Ernst Boris Chain and Norman Heatley – to form what we today know as penicillin . In 1940, penicillin became available for medicinal use to treat bacterial infections in humans. The field of modern biotechnology is generally thought of as having been born in 1971 when Paul Berg's (Stanford) experiments in gene splicing had early success. Herbert W. Boyer (Univ. Calif. at San Francisco) and Stanley N. Cohen (Stanford) significantly advanced
9144-511: The application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials and organisms, such as pharmaceuticals, crops, and livestock . As per the European Federation of Biotechnology , biotechnology is the integration of natural science and organisms, cells, parts thereof, and molecular analogues for products and services. Biotechnology
9271-471: The broad definition of "utilizing a biotechnological system to make products". Indeed, the cultivation of plants may be viewed as the earliest biotechnological enterprise. Agriculture has been theorized to have become the dominant way of producing food since the Neolithic Revolution . Through early biotechnology, the earliest farmers selected and bred the best-suited crops (e.g., those with
9398-509: The course of their PhD thesis work. Nineteen institutions offer NIGMS supported BTPs. Biotechnology training is also offered at the undergraduate level and in community colleges. But see also: Domingo, José L.; Bordonaba, Jordi Giné (2011). "A literature review on the safety assessment of genetically modified plants" (PDF) . Environment International . 37 (4): 734–742. Bibcode : 2011EnInt..37..734D . doi : 10.1016/j.envint.2011.01.003 . PMID 21296423 . Archived (PDF) from
9525-445: The current decades, significant progress has been done in creating genetically modified organisms (GMOs) that enhance the diversity of applications and economical viability of industrial biotechnology. By using renewable raw materials to produce a variety of chemicals and fuels, industrial biotechnology is actively advancing towards lowering greenhouse gas emissions and moving away from a petrochemical-based economy. Synthetic biology
9652-488: The difference between beneficial biotechnology (e.g., bioremediation is to clean up an oil spill or hazard chemical leak) versus the adverse effects stemming from biotechnological enterprises (e.g., flow of genetic material from transgenic organisms into wild strains) can be seen as applications and implications, respectively. Cleaning up environmental wastes is an example of an application of environmental biotechnology ; whereas loss of biodiversity or loss of containment of
9779-458: The discovery and manufacturing of traditional small molecule pharmaceutical drugs as well as drugs that are the product of biotechnology – biopharmaceutics . Modern biotechnology can be used to manufacture existing medicines relatively easily and cheaply. The first genetically engineered products were medicines designed to treat human diseases. To cite one example, in 1978 Genentech developed synthetic humanized insulin by joining its gene with
9906-763: The dominant Indigenous group when Europeans arrived in the early 17th century, and they were subdivived into dialectal groups such as the Munsee, in the north, and the Unami and the Unalachtigo, elsewhere. Dutch and Swedish colonists founded the first European settlements in the state, with the British later seizing control of the region and establishing the Province of New Jersey , named after Jersey . The colony's fertile lands and relative religious tolerance drew
10033-402: The early 2000s, BioFETs such as the DNA field-effect transistor (DNAFET), gene-modified FET (GenFET) and cell-potential BioFET (CPFET) had been developed. A factor influencing the biotechnology sector's success is improved intellectual property rights legislation—and enforcement—worldwide, as well as strengthened demand for medical and pharmaceutical products. Rising demand for biofuels
10160-616: The extreme southern and northwestern counties are relatively less dense overall. Since the 2000 census, the United States Census Bureau calculated that New Jersey's center of population was located in East Brunswick . The state is located in the middle of the Northeast megalopolis , which has more than 50 million residents. As of 2019, New Jersey was the third highest U.S. state measured by median household income , behind Maryland and Massachusetts ;
10287-607: The fact these organisms are subject to intellectual property law. Biotechnology has several applications in the realm of food security. Crops like Golden rice are engineered to have higher nutritional content, and there is potential for food products with longer shelf lives. Though not a form of agricultural biotechnology, vaccines can help prevent diseases found in animal agriculture. Additionally, agricultural biotechnology can expedite breeding processes in order to yield faster results and provide greater quantities of food. Transgenic biofortification in cereals has been considered as
10414-468: The first biosensor in 1962. Biosensor MOSFETs were later developed, and they have since been widely used to measure physical , chemical , biological and environmental parameters. The first BioFET was the ion-sensitive field-effect transistor (ISFET), invented by Piet Bergveld in 1970. It is a special type of MOSFET, where the metal gate is replaced by an ion -sensitive membrane , electrolyte solution and reference electrode . The ISFET
10541-416: The first forms of biotechnology. These processes also were included in early fermentation of beer . These processes were introduced in early Mesopotamia , Egypt , China and India , and still use the same basic biological methods. In brewing , malted grains (containing enzymes ) convert starch from grains into sugar and then adding specific yeasts to produce beer. In this process, carbohydrates in
10668-674: The first ten years of English rule took place along the Hackensack River and Arthur Kill . Settlers came primarily from New York and New England. On March 18, 1673, Berkeley sold his half of the colony to Quakers in England, who settled the Delaware Valley region as a Quaker colony, with William Penn acting as trustee for the lands for a time. New Jersey was governed as two distinct provinces, East and West Jersey , for 28 years between 1674 and 1702, which were part of
10795-458: The following articles: New Jersey is one of the most ethnically and religiously diverse states in the United States. Nearly one-fourth of New Jerseyans (22.7%) were foreign born , compared to the national average of 13.5%. As of 2011, 56.4% of New Jersey's children under the age of one belonged to racial or ethnic minority groups, meaning that they had at least one parent who was not non-Hispanic white. The 2019 Vintage Year Census estimated that
10922-442: The governors of New York, but this infuriated the settlers of New Jersey, who accused these governors of favoritism to New York. Judge Lewis Morris led the case for a separate governor, and was appointed governor by King George II in 1738. New Jersey was one of the Thirteen Colonies that revolted against British rule in the American Revolution . The New Jersey Constitution of 1776 was passed July 2, 1776, just two days before
11049-416: The grains broke down into alcohols, such as ethanol. Later, other cultures produced the process of lactic acid fermentation , which produced other preserved foods, such as soy sauce . Fermentation was also used in this time period to produce leavened bread . Although the process of fermentation was not fully understood until Louis Pasteur 's work in 1857, it is still the first use of biotechnology to convert
11176-418: The highest annual median household income , at $ 96,346, of all 50 states. Almost one-tenth of all households in the state, or over 323,000, are millionaires , the highest representation of millionaires among all states. New Jersey's public school system consistently ranks at or among the top of all U.S. states. In 2024, New Jersey was ranked as having the second-healthiest population overall. New Jersey
11303-436: The highest number of millionaires both per capita and per square mile in the U.S., and the fact that it has the most scientists and engineers per square mile in the world. According to HUD 's 2022 Annual Homeless Assessment Report , there were an estimated 8,752 homeless people in New Jersey. The top countries of origin for New Jersey's immigrants in 2018 were India , Dominican Republic , Mexico , Ecuador , and
11430-478: The highest yields) to produce enough food to support a growing population. As crops and fields became increasingly large and difficult to maintain, it was discovered that specific organisms and their by-products could effectively fertilize , restore nitrogen , and control pests . Throughout the history of agriculture, farmers have inadvertently altered the genetics of their crops through introducing them to new environments and breeding them with other plants — one of
11557-718: The market, but in 2015 the FDA approved the first GM salmon for commercial production and consumption. There is a scientific consensus that currently available food derived from GM crops poses no greater risk to human health than conventional food, but that each GM food needs to be tested on a case-by-case basis before introduction. Nonetheless, members of the public are much less likely than scientists to perceive GM foods as safe. The legal and regulatory status of GM foods varies by country, with some nations banning or restricting them, and others permitting them with widely differing degrees of regulation. GM crops also provide
11684-815: The methods of genetic engineering . These techniques have allowed for the introduction of new crop traits as well as a far greater control over a food's genetic structure than previously afforded by methods such as selective breeding and mutation breeding . Commercial sale of genetically modified foods began in 1994, when Calgene first marketed its Flavr Savr delayed ripening tomato. To date most genetic modification of foods have primarily focused on cash crops in high demand by farmers such as soybean , corn , canola , and cotton seed oil . These have been engineered for resistance to pathogens and herbicides and better nutrient profiles. GM livestock have also been experimentally developed; in November 2013 none were available on
11811-419: The most populous is Hackensack , with 46,030 residents. Many urban areas extend far beyond the limits of a single large city, as New Jersey municipalities tend to be geographically small; three of the four largest cities in New Jersey by population have under 20 square miles (52 km ) of land area, and eight of the top ten, including all the top five, have a land area under 30 square miles (78 km ). As of
11938-542: The new technology in 1972 by transferring genetic material into a bacterium, such that the imported material would be reproduced. The commercial viability of a biotechnology industry was significantly expanded on June 16, 1980, when the United States Supreme Court ruled that a genetically modified microorganism could be patented in the case of Diamond v. Chakrabarty . Indian-born Ananda Chakrabarty , working for General Electric , had modified
12065-417: The northeastern United States. Hurricanes and tropical storms , tornadoes , and earthquakes are rare; the state was impacted by a hurricane in 1903 , Tropical Storm Floyd in 1999 , and Hurricane Sandy in 2012 , which made landfall in the state with top winds of 90 mph (145 km/h). Climate change is affecting New Jersey faster than much of the rest of the United States. Climatologists at
12192-578: The northwest of the state, to 7B near Cape May. All-time temperature extremes recorded in New Jersey include 110 °F (43 °C) on July 10, 1936, in Runyon , Middlesex County and −34 °F (−37 °C) on January 5, 1904, in River Vale , Bergen County. Average annual precipitation ranges from 43 to 51 inches (1,100 to 1,300 mm), spread uniformly throughout the year. Average snowfall per winter season ranges from 10–15 inches (25–38 cm) in
12319-404: The original on October 9, 2022. In spite of this, the number of studies specifically focused on safety assessment of GM plants is still limited. However, it is important to remark that for the first time, a certain equilibrium in the number of research groups suggesting, on the basis of their studies, that a number of varieties of GM products (mainly maize and soybeans) are as safe and nutritious as
12446-463: The production of a chemical known as 1,4-butanediol , which is used in fiber manufacturing. In order to produce 1,4-butanediol, the authors alter the metabolic regulation of the Escherichia coli by CRISPR to induce point mutation in the glt A gene, knockout of the sad gene, and knock-in six genes ( cat 1, suc D, 4hbd , cat 2, bld , and bdh ). Whereas CRISPRi system used to knockdown
12573-460: The production of crops and livestock to use them for food. In selective breeding, organisms with desirable characteristics are mated to produce offspring with the same characteristics. For example, this technique was used with corn to produce the largest and sweetest crops. In the early twentieth century scientists gained a greater understanding of microbiology and explored ways of manufacturing specific products. In 1917, Chaim Weizmann first used
12700-438: The production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast , and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science . One of the key techniques used in biotechnology
12827-441: The products). The utilization of biological processes, organisms or systems to produce products that are anticipated to improve human lives is termed biotechnology. By contrast, bioengineering is generally thought of as a related field that more heavily emphasizes higher systems approaches (not necessarily the altering or using of biological materials directly ) for interfacing with and utilizing living things. Bioengineering
12954-422: The purpose of sustainable operations (for the return from bottomless initial investment on R & D) and gaining durable patents rights (for exclusives rights for sales, and prior to this to receive national and international approval from the results on animal experiment and human experiment, especially on the pharmaceutical branch of biotechnology to prevent any undetected side-effects or safety concerns by using
13081-470: The regulation of GMOs between countries, with some of the most marked differences occurring between the US and Europe. Regulation varies in a given country depending on the intended use of the products of the genetic engineering. For example, a crop not intended for food use is generally not reviewed by authorities responsible for food safety. The European Union differentiates between approval for cultivation within
13208-404: The respective conventional non-GM plant, and those raising still serious concerns, was observed. Moreover, it is worth mentioning that most of the studies demonstrating that GM foods are as nutritional and safe as those obtained by conventional breeding, have been performed by biotechnology companies or associates, which are also responsible of commercializing these GM plants. Anyhow, this represents
13335-533: The second state constitution was ratified and brought into effect. Counties thereby became districts for the state senate, and some realignment of boundaries (including the creation of Mercer County ) immediately followed. This provision was retained in the 1947 Constitution, but was overturned by the Supreme Court of the United States in 1962, by the decision Baker v. Carr . While the Governorship
13462-645: The signing of the Treaty of Paris , which ended the war. On December 18, 1787, New Jersey became the third state to ratify the United States Constitution , which was overwhelmingly popular in New Jersey since it prevented New York and Pennsylvania from charging tariffs on goods imported from Europe. On November 20, 1789, New Jersey became the first in the newly formed Union to ratify the Bill of Rights . The 1776 New Jersey State Constitution gave
13589-494: The south and near the seacoast, 15–30 inches (38–76 cm) in the northeast and central part of the state, to about 40–50 inches (1.0–1.3 m) in the northwestern highlands, but this often varies considerably from year to year. Precipitation falls on an average of 120 days a year, with 25 to 30 thunderstorms, most of which occur during the summer. During winter and early spring, New Jersey can experience nor'easters , which are capable of causing blizzards or flooding throughout
13716-414: The southwestern counties of the state, which reside within the Delaware Valley surrounding Philadelphia . Despite its heavily urban character and a long history of industrialization , forests cover roughly 45 percent of New Jersey's land area, or approximately 2.1 million acres (8,500 km ), ranking 31st among the 50 U.S. states and six territories. Northwestern New Jersey, often referred to as
13843-545: The state enlisted in the Union army; unlike many states, including some Northern ones, no battle was fought there. In the Industrial Revolution , cities like Paterson grew and prospered. Previously, the economy had been largely agrarian, which was problematically subject to crop failures and poor soil. This caused a shift to a more industrialized economy, one based on manufactured commodities such as textiles and silk. Inventor Thomas Edison also became an important figure of
13970-429: The state's ethnic makeup was as follows: 71.9% White alone, 15.1% Black or African American alone, 10.0% Asian alone, 0.6% American Indian and Alaska Native alone, 0.1% Native Hawaiian and Other Pacific Islander alone, and 2.3% Two or more races. Hispanic or Latino accounted for 20.9%, while White alone (non-Hispanic or Latino) accounted for 54.6% of the population. Many of the municipalities in Bergen County, New Jersey ,
14097-417: The state's largest county, have a sizeable minority population of Hispanics and Asians. Biotechnology Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services. The term biotechnology was first used by Károly Ereky in 1919 to refer to
14224-437: The state's median household income was over $ 85,000 compared to the national average of roughly $ 65,000. Conversely, New Jersey's poverty rate of 9.4% was slightly lower than the national average of 11.4%, and the sixth lowest of the fifty states, Washington, D.C., and Puerto Rico . This is attributed to several factors, including the state's proximity to the major economic centers of New York City and Philadelphia , its hosting
14351-434: The state, but temperatures can, for brief periods, fall below 10 °F (−12 °C) and sometimes rise above 50 °F (10 °C). Northwestern parts of the state have significantly colder winters with sub-0 °F (−18 °C) being an almost annual occurrence. Spring and autumn may feature wide temperature variations, with lower humidity than summer. The USDA Plant Hardiness Zone classification ranges from 6 in
14478-534: The three competing genes ( gab D, ybg C, and tes B) that affect the biosynthesis pathway of 1,4-butanediol. Consequently, the yield of 1,4-butanediol significantly increased from 0.9 to 1.8 g/L. Environmental biotechnology includes various disciplines that play an essential role in reducing environmental waste and providing environmentally safe processes, such as biofiltration and biodegradation . The environment can be affected by biotechnologies, both positively and adversely. Vallero and others have argued that
14605-542: The time, testing is used to find changes that are associated with inherited disorders. The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person's chance of developing or passing on a genetic disorder . As of 2011 several hundred genetic tests were in use. Since genetic testing may open up ethical or psychological problems, genetic testing is often accompanied by genetic counseling . Genetically modified crops ("GM crops", or "biotech crops") are plants used in agriculture ,
14732-570: The total company value of pharmaceutical biotech companies worldwide were active in Oncology with Neurology and Rare Diseases being the other two big applications. Pharmacogenomics (a combination of pharmacology and genomics ) is the technology that analyses how genetic makeup affects an individual's response to drugs. Researchers in the field investigate the influence of genetic variation on drug responses in patients by correlating gene expression or single-nucleotide polymorphisms with
14859-470: The vote to all inhabitants who had a certain level of wealth. This included women and Black people, but not married women because they were not legally permitted to own property separately from their husbands. Both sides, in several elections, claimed that the other side had had unqualified women vote and mocked them for use of petticoat electors, whether entitled to vote or not; on the other hand, both parties passed Voting Rights Acts. In 1807, legislature passed
14986-577: The west by Pennsylvania across the Delaware River . New Jersey is broadly divided into the North , Central , and South Jersey geographic regions, although some residents do not consider Central Jersey a region in its own right. Across the regions are five distinct areas divided by natural geography and population concentration. Northeastern New Jersey, often referred to as the Gateway Region , lies closest to Manhattan in New York City, and up to
15113-507: The world's crop lands were planted with GM crops in 2010. As of 2011, 11 different transgenic crops were grown commercially on 395 million acres (160 million hectares) in 29 countries such as the US, Brazil , Argentina , India , Canada, China, Paraguay, Pakistan, South Africa, Uruguay, Bolivia, Australia, Philippines, Myanmar, Burkina Faso, Mexico and Spain. Genetically modified foods are foods produced from organisms that have had specific changes introduced into their DNA with
15240-865: The zeppelin airship Hindenburg crashed in flames over Lakehurst , and the SS Morro Castle beached itself near Asbury Park after going up in flames while at sea. Through both World Wars , New Jersey was a center for war production, especially naval construction. The Federal Shipbuilding and Drydock Company yards in Kearny and Newark and the New York Shipbuilding Corporation yard in Camden produced aircraft carriers , battleships, cruisers, and destroyers. New Jersey manufactured 6.8 percent of total United States military armaments produced during World War II , ranking fifth among
15367-436: Was Michiel Pauw , who established a patron ship called Pavonia in 1630 along North River , that eventually became Bergen . Peter Minuit 's purchase of lands along the Delaware River established the colony of New Sweden , that lasted until the Dutch conquered it in 1655. Then the entire region became a territory of England on June 24, 1664, after an English fleet under command of Colonel Richard Nicolls sailed into what
15494-556: Was also a leading industry during the middle to late 19th century. Bog iron pits in the New Jersey Pine Barrens were among the first sources of iron for the new nation. Mines such as Mt. Hope, Mine Hill, and the Rockaway Valley Mines created a thriving industry. Mining generated the impetus for new towns and was one of the driving forces behind the need for the Morris Canal . Zinc mines were also
15621-557: Was credited with a revitalization of Hudson County and Jersey City . Urban revitalization has continued in North Jersey in the 21st century. In 2014, Jersey City's Census-estimated population was 262,146, with the largest population increase of any municipality in New Jersey since 2010, representing an increase of 5.9% from the 2010 U.S. census , when the city's population was enumerated at 247,597. Between 2000 and 2010 Newark experienced its first population increase since
15748-514: Was named the Province of New Jersey . Since its inception, New Jersey has been characterized by ethnic and religious diversity . New England Congregationalists settled alongside Scots Presbyterians and Dutch Reformed migrants. While the majority of residents lived in towns with individual landholdings of 100 acres (40 ha), a few rich proprietors owned vast estates. English Quakers and Anglicans owned large landholdings. Unlike Plymouth Colony , Jamestown and other colonies, New Jersey
15875-556: Was populated by a secondary wave of immigrants who came from other colonies instead of those who migrated directly from Europe. New Jersey remained agrarian and rural throughout the colonial era, and commercial farming developed sporadically. Some townships, such as Burlington on the Delaware River and Perth Amboy , emerged as important ports for shipping to New York City and Philadelphia. The colony's fertile lands and tolerant religious policy drew more settlers, and New Jersey's population had increased to 120,000 by 1775. Settlement for
16002-535: Was ranked as the fourth most diverse state in 2024. New Jersey ranks near the top on both the American Human Development Index and the standard Human Development Index . According to climatology research by the U.S. National Oceanic and Atmospheric Administration , New Jersey has been the fastest-warming state by average air temperature over a 100-year period beginning in the early 20th century, which has been attributed to warming of
16129-494: Was stronger than under the 1776 constitution, the constitution of 1844 created many offices that were not responsible to him, or to the people, and it gave him a three-year term, but he could not succeed himself. New Jersey was one of the few Union states (the others being Delaware and Kentucky ) to select a candidate other than Abraham Lincoln twice in national elections, and sided with Stephen A. Douglas (1860) and George B. McClellan (1864) during their campaigns. McClellan,
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