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82-736: On April 16, a downed power line started the Sweat Farm Road fire southwest of Waycross . When it entered the Okefenokee National Wildlife Refuge on April 21, it was renamed Big Turnaround. Close by, the Bugaboo fire was ignited by lightning on May 5. By May 20, the fires converged and became the Georgia Bay Complex - one of the largest fires in the South and the nation. This fire started when

164-569: A combination of genetic and environmental factors . Environmental factors include exposure to air pollution and allergens . Other potential triggers include medications such as aspirin and beta blockers . Diagnosis is usually based on the pattern of symptoms, response to therapy over time, and spirometry lung function testing. Asthma is classified according to the frequency of symptoms of forced expiratory volume in one second (FEV 1 ), and peak expiratory flow rate . It may also be classified as atopic or non-atopic, where atopy refers to

246-406: A combination of factors, including poor treatment adherence, increased allergen and viral exposure, and altered immune tolerance. There is limited evidence to guide possible approaches to reducing autumn exacerbations, but while costly, seasonal omalizumab treatment from four to six weeks before school return may reduce autumn asthma exacerbations. Asthma is the result of chronic inflammation of

328-456: A common cause of acute attacks in women and children. Both viral and bacterial infections of the upper respiratory tract can worsen the disease. Psychological stress may worsen symptoms – it is thought that stress alters the immune system and thus increases the airway inflammatory response to allergens and irritants. Asthma exacerbations in school-aged children peak in autumn, shortly after children return to school. This might reflect

410-475: A major "hump"-type classification yard . On the National Register of Historic Places : Asthma Asthma is a common long-term inflammatory disease of the airways of the lungs . Asthma occurs when allergens , pollen , dust, or other particles, are inhaled into the lungs, causing the bronchioles to constrict and produce mucus, which then restricts oxygen flow to the alveoli . It

492-412: A person's asthma is controlled. The methacholine challenge involves the inhalation of increasing concentrations of a substance that causes airway narrowing in those predisposed. If negative it means that a person does not have asthma; if positive, however, it is not specific for the disease. Other supportive evidence includes: a ≥20% difference in peak expiratory flow rate on at least three days in

574-478: A pre-school, six elementary schools, two middle schools, and one high school. The district has 431 full-time teachers and over 6,370 students. U.S. Highway 1 runs north–south through Waycross, while concurrent with U.S. Highway 23 . U.S. Highway 82 is an east–west highway in Waycross. U.S. Highway 84 runs east–west through Waycross. There are no limited-access highways anywhere near Waycross; Interstate 75

656-491: A predisposition toward developing a type 1 hypersensitivity reaction. There is no known cure for asthma, but it can be controlled. Symptoms can be prevented by avoiding triggers, such as allergens and respiratory irritants , and suppressed with the use of inhaled corticosteroids . Long-acting beta agonists (LABA) or antileukotriene agents may be used in addition to inhaled corticosteroids if asthma symptoms remain uncontrolled. Treatment of rapidly worsening symptoms

738-619: A proclamation to establish the Laura S Walker National Park in her honor. She was the only living person for whom a state or national park was named. In 1937, the federal government purchased distressed farmland for the park. Work on the park was undertaken by the Works Progress Administration and the Civilian Conservation Corps . In 1941, the national park was deeded over to Georgia, becoming

820-497: A result of the smoke. Smoke at times reduced visibility as far south as central Florida , and was even blown all the way down to Fort Lauderdale in south Florida , putting the local air quality index in the unhealthy range. Smoke later drifted across southern Alabama and even to Meridian, Mississippi . By June 22, the wildfires in Georgia were largely contained. The containment came after beneficial, heavy rain blanketed

902-413: A significantly higher risk compared to randomly selected controls ( odds ratio 7.2, 95% confidence interval 5.2–10). Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction

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984-585: A third of people. This may be even more common in some ethnic groups such as the Japanese and those with aspirin-exacerbated respiratory disease. Other studies have found improvement in asthmatic symptoms from alcohol. Non-atopic asthma, also known as intrinsic or non-allergic, makes up between 10 and 33% of cases. There is negative skin test to common inhalant allergens. Often it starts later in life, and women are more commonly affected than men. Usual treatments may not work as well. The concept that "non-atopic"

1066-467: A tree fell on a power line on April 16, during high winds (caused by the April 2007 nor'easter and a strong high-pressure system ), and low humidity along with drought conditions. By April 30, it had burned about 80,000 acres (320 km)—about 20% of which was in the refuge—and had also destroyed 22 homes, and forced the evacuations of over 1,000 people. A fire break 12 miles (19 km) long

1148-429: A trigger for asthma; formaldehyde exposure, for example, has a positive association. Phthalates in certain types of PVC are associated with asthma in both children and adults. While exposure to pesticides is linked to the development of asthma, a cause and effect relationship has yet to be established. A meta-analysis concluded gas stoves are a major risk factor for asthma, finding around one in eight cases in

1230-675: A trip to the Okefenokee Swamp . The tradition faded away after the interstates opened through Georgia. In the mid-1990s, the Flanders Hamburgers , a frozen hamburger that needed no defrosting, was created in Waycross. This was the creation of Eaves Foods, Inc., a company that later changed to Flanders, LLC. in 2000. Bubba Burgers are now sold nationwide as well as worldwide through the United States Military Commissary system. Waycross

1312-432: A week for at least two weeks, a ≥20% improvement of peak flow following treatment with either salbutamol, inhaled corticosteroids or prednisone, or a ≥20% decrease in peak flow following exposure to a trigger. Testing peak expiratory flow is more variable than spirometry, however, and thus not recommended for routine diagnosis. It may be useful for daily self-monitoring in those with moderate to severe disease and for checking

1394-515: Is 60 miles to the west, and Interstate 95 is 40 miles to the east. Waycross-Ware County Airport (IATA: AYS, ICAO: KAYS, FAA LID: AYS) is a public airport located three miles (5 km) northwest of the central business district of Waycross. It is owned by the City of Waycross and Ware County. Six railroad lines meet at Waycross, making it a logical location for shunting freight to different destinations. CSX Transportation operates Rice Yard here,

1476-1016: Is a commonly reported occupational disease . Many cases, however, are not reported or recognized as such. It is estimated that 5–25% of asthma cases in adults are work-related. A few hundred different agents have been implicated, with the most common being isocyanates , grain and wood dust, colophony , soldering flux , latex , animals, and aldehydes . The employment associated with the highest risk of problems include those who spray paint , bakers and those who process food, nurses, chemical workers, those who work with animals, welders , hairdressers and timber workers. Aspirin-exacerbated respiratory disease (AERD), also known as aspirin -induced asthma, affects up to 9% of asthmatics. AERD consists of asthma, nasal polyps, sinus disease, and respiratory reactions to aspirin and other NSAID medications (such as ibuprofen and naproxen). People often also develop loss of smell and most experience respiratory reactions to alcohol. Alcohol may worsen asthmatic symptoms in up to

1558-429: Is a history of atopic disease ; with asthma occurring at a much greater rate in those who have either eczema or hay fever . Asthma has been associated with eosinophilic granulomatosis with polyangiitis (formerly known as Churg–Strauss syndrome), an autoimmune disease and vasculitis . Individuals with certain types of urticaria may also experience symptoms of asthma. There is a correlation between obesity and

1640-456: Is a kind of asthma distinguishable by recurrent, severe attacks. Type 1 brittle asthma is a disease with wide peak flow variability, despite intense medication. Type 2 brittle asthma is background well-controlled asthma with sudden severe exacerbations. Exercise can trigger bronchoconstriction both in people with or without asthma. It occurs in most people with asthma and up to 20% of people without asthma. Exercise-induced bronchoconstriction

1722-602: Is a leading center in health care in the area. The three-story facility has a trauma unit, cancer care unit, outpatient surgery and imaging services. In 2012, Satilla Regional Medical Center joined the Mayo Clinic Health System and became the Mayo Clinic Health System in Waycross. The Mayo Clinic ceased operations of the hospital in 2015. The hospital later joined HCA Healthcare and has since been renamed Memorial Satilla Health. The Ware County School District holds pre-school to grade twelve, and consists of

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1804-503: Is a specific single nucleotide polymorphism in the CD14 region and exposure to endotoxin (a bacterial product). Endotoxin exposure can come from several environmental sources including tobacco smoke, dogs, and farms. Risk for asthma, then, is determined by both a person's genetics and the level of endotoxin exposure. A triad of atopic eczema , allergic rhinitis and asthma is called atopy. The strongest risk factor for developing asthma

1886-499: Is a well-recognized condition, there is not one universal agreed-upon definition. It is defined by the Global Initiative for Asthma as "a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. The chronic inflammation is associated with airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing particularly at night or in

1968-732: Is affected, the probability of the other having the disease is approximately 25%. By the end of 2005, 25 genes had been associated with asthma in six or more separate populations, including GSTM1 , IL10 , CTLA-4 , SPINK5 , LTC4S , IL4R and ADAM33 , among others. Many of these genes are related to the immune system or modulating inflammation. Even among this list of genes supported by highly replicated studies, results have not been consistent among all populations tested. In 2006 over 100 genes were associated with asthma in one genetic association study alone; more continue to be found. Some genetic variants may only cause asthma when they are combined with specific environmental exposures. An example

2050-594: Is associated with a greater risk of asthma-like symptoms. Low air quality from environmental factors such as traffic pollution or high ozone levels has been associated with both asthma development and increased asthma severity. Over half of cases in children in the United States occur in areas when air quality is below the EPA standards. Low air quality is more common in low-income and minority communities. Exposure to indoor volatile organic compounds may be

2132-500: Is associated with an increased risk of asthma in the child. Some individuals will have stable asthma for weeks or months and then suddenly develop an episode of acute asthma. Different individuals react to various factors in different ways. Most individuals can develop severe exacerbation from a number of triggering agents. Home factors that can lead to exacerbation of asthma include dust , animal dander (especially cat and dog hair), cockroach allergens and mold . Perfumes are

2214-504: Is associated with exposure to indoor allergens. Common indoor allergens include dust mites , cockroaches , animal dander (fragments of fur or feathers), and mould. Efforts to decrease dust mites have been found to be ineffective on symptoms in sensitized subjects. Weak evidence suggests that efforts to decrease mould by repairing buildings may help improve asthma symptoms in adults. Certain viral respiratory infections, such as respiratory syncytial virus and rhinovirus , may increase

2296-435: Is attributed to the lack of healthy bacterial colonization that the newborn would have acquired from passage through the birth canal. There is a link between asthma and the degree of affluence which may be related to the hygiene hypothesis as less affluent individuals often have more exposure to bacteria and viruses. Family history is a risk factor for asthma, with many different genes being implicated. If one identical twin

2378-977: Is believed that the recent increased rates of asthma are due to changing epigenetics ( heritable factors other than those related to the DNA sequence ) and a changing living environment. Asthma that starts before the age of 12 years old is more likely due to genetic influence, while onset after age 12 is more likely due to environmental influence. Many environmental factors have been associated with asthma's development and exacerbation, including allergens, air pollution, and other environmental chemicals. There are some substances that are known to cause asthma in exposed people and they are called asthmagens . Some common asthmagens include ammonia, latex, pesticides, solder and welding fumes, metal or wood dusts, spraying of isocyanate paint in vehicle repair, formaldehyde, glutaraldehyde, anhydrides, glues, dyes, metal working fluids, oil mists, moulds. Smoking during pregnancy and after delivery

2460-406: Is characterized by variable and recurring symptoms, reversible airflow obstruction , and easily triggered bronchospasms . Symptoms include episodes of wheezing , coughing , chest tightness, and shortness of breath . These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by

2542-427: Is classified based on severity, at the moment there is no clear method for classifying different subgroups of asthma beyond this system. Finding ways to identify subgroups that respond well to different types of treatments is a current critical goal of asthma research. Recently, asthma has been classified based on whether it is associated with type 2 or non–type 2 inflammation. This approach to immunologic classification

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2624-437: Is common in professional athletes. The highest rates are among cyclists (up to 45%), swimmers, and cross-country skiers. While it may occur with any weather conditions, it is more common when it is dry and cold. Inhaled beta 2 agonists do not appear to improve athletic performance among those without asthma; however, oral doses may improve endurance and strength. Asthma as a result of (or worsened by) workplace exposures

2706-464: Is commonly referred to as an asthma attack . The classic symptoms are shortness of breath , wheezing , and chest tightness . The wheezing is most often when breathing out. While these are the primary symptoms of asthma, some people present primarily with coughing , and in severe cases, air motion may be significantly impaired such that no wheezing is heard. In children, chest pain is often present. Signs occurring during an asthma attack include

2788-430: Is correlated with more exposure to cigarette smoke, an older age, less symptom reversibility after bronchodilator administration, and decreased likelihood of family history of atopy. The evidence for the effectiveness of measures to prevent the development of asthma is weak. The World Health Organization recommends decreasing risk factors such as tobacco smoke, air pollution, chemical irritants including perfume , and

2870-436: Is driven by a developing understanding of the underlying immune processes and by the development of therapeutic approaches that target type 2 inflammation. Although asthma is a chronic obstructive condition, it is not considered as a part of chronic obstructive pulmonary disease , as this term refers specifically to combinations of disease that are irreversible such as bronchiectasis and emphysema . Unlike these diseases,

2952-399: Is insufficient, the use of medication is recommended. Pharmaceutical drugs are selected based on, among other things, the severity of illness and the frequency of symptoms. Specific medications for asthma are broadly classified into fast-acting and long-acting categories. The medications listed below have demonstrated efficacy in improving asthma symptoms; however, real world use-effectiveness

3034-537: Is limited as around half of people with asthma worldwide remain sub-optimally controlled, even when treated. People with asthma may remain sub-optimally controlled either because optimum doses of asthma medications do not work (called "refractory" asthma) or because individuals are either unable (e.g. inability to afford treatment, poor inhaler technique) or unwilling (e.g., wish to avoid side effects of corticosteroids) to take optimum doses of prescribed asthma medications (called "difficult to treat" asthma). In practice, it

3116-490: Is located at 31°12′50″N 82°21′18″W  /  31.21389°N 82.35500°W  / 31.21389; -82.35500 (31.213860, -82.354911) and is the closest city to the Okefenokee Swamp . According to the United States Census Bureau , the city has a total area of 11.7 square miles (30 km ), of which 11.7 square miles (30 km ) is land and 0.04 square miles (0.10 km ) (0.17%)

3198-434: Is not known whether asthma causes psychological problems or psychological problems lead to asthma. Current asthma, but not former asthma, is associated with increased all-cause mortality, heart disease mortality, and chronic lower respiratory tract disease mortality. Asthma, particularly severe asthma, is strongly associated with development of chronic obstructive pulmonary disease (COPD). Those with asthma, especially if it

3280-452: Is not possible to distinguish "refractory" from "difficult to treat" categories for patients who have never taken optimum doses of asthma medications. A related issue is that the asthma efficacy trials upon which the pharmacological treatment guidelines are based have systematically excluded the majority of people with asthma. For example, asthma efficacy treatment trials always exclude otherwise eligible people who smoke, and smoking diminishes

3362-478: Is poorly controlled, are at increased risk for radiocontrast reactions. Cavities occur more often in people with asthma. This may be related to the effect of beta 2 -adrenergic agonists decreasing saliva. These medications may also increase the risk of dental erosions . Asthma is caused by a combination of complex and incompletely understood environmental and genetic interactions. These influence both its severity and its responsiveness to treatment. It

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3444-421: Is supportive of the diagnosis. It however may be normal in those with a history of mild asthma, not currently acting up. As caffeine is a bronchodilator in people with asthma, the use of caffeine before a lung function test may interfere with the results. Single-breath diffusing capacity can help differentiate asthma from COPD . It is reasonable to perform spirometry every one or two years to follow how well

3526-412: Is synonymous with "non-allergic" is called into question by epidemiological data that the prevalence of asthma is closely related to the serum IgE level standardized for age and sex (P<0.0001), indicating that asthma is almost always associated with some sort of IgE-related reaction and therefore has an allergic basis, although not all the allergic stimuli that cause asthma appear to have been included in

3608-722: Is the type 2-high/type 2-low distinction. Classification based on type 2 inflammation is useful in predicting which patients will benefit from targeted biologic therapy . Many other conditions can cause symptoms similar to those of asthma. In children, symptoms may be due to other upper airway diseases such as allergic rhinitis and sinusitis , as well as other causes of airway obstruction including foreign body aspiration , tracheal stenosis , laryngotracheomalacia , vascular rings , enlarged lymph nodes or neck masses. Bronchiolitis and other viral infections may also produce wheezing. According to European Respiratory Society , it may not be suitable to label wheezing preschool children with

3690-482: Is then used to confirm the diagnosis. In children under the age of six the diagnosis is more difficult as they are too young for spirometry. Spirometry is recommended to aid in diagnosis and management. It is the single best test for asthma. If the FEV 1 measured by this technique improves more than 12% and increases by at least 200 millilitres following administration of a bronchodilator such as salbutamol , this

3772-423: Is usually with an inhaled short-acting beta 2 agonist such as salbutamol and corticosteroids taken by mouth. In very severe cases, intravenous corticosteroids, magnesium sulfate , and hospitalization may be required. In 2019 asthma affected approximately 262 million people and caused approximately 461,000 deaths. Most of the deaths occurred in the developing world . Asthma often begins in childhood, and

3854-655: Is water. The closest major city is Jacksonville, Florida , which is roughly 81 miles away. In May 2010, the city purchased the Bandalong Litter Trap and installed it in Tebeau Creek, a tributary of the Satilla River . The trap was invented in Australia , but is manufactured in the United States. Although the city has maintained a good standing with the state's Environmental Protection Division,

3936-549: The Georgia State Patrol and Florida Highway Patrol doubled the distance to travel between Valdosta and Gainesville (from 90 miles (145 km) to 180) and tripled the time normally required to make the trip. Hundreds were evacuated from homes in Columbia County, Florida late on May 10, and a state of emergency was declared. During the time these fires were burning, thick, sooty smoke blanketed

4018-654: The National Register of Historic Places , including the U.S. Post Office and Courthouse , Lott Cemetery , the First African Baptist Church and Parsonage , and the Obediah Barber Homestead (which is seven miles south of the city). The area now known as Waycross was first settled circa 1820, locally known as "Old Nine" or "Number Nine" and then Pendleton. It was renamed Tebeauville in 1857, incorporated under that name in 1866, and designated county seat of Ware County in 1873. It

4100-465: The Okefenokee National Wildlife Refuge . Many cities were threatened, but were never under siege. Subtropical Storm Andrea —which some had hoped might bring relief—apparently exacerbated the situation, as it drove strong winds into the fire but brought very little rain . These winds may have been the reason that the fire then blew across the border into northeast Florida . On May 8, the Bugaboo fire

4182-414: The conducting zone of the airways (most especially the bronchi and bronchioles ), which subsequently results in increased contractability of the surrounding smooth muscles . This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. The narrowing is typically reversible with or without treatment. Occasionally the airways themselves change. Typical changes in

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4264-423: The "infectious asthma" (IA) syndrome, or as "asthma associated with infection" (AAWI) to distinguish infection-associated asthma initiation from the well known association of respiratory infections with asthma exacerbations. Reported clinical prevalences of IA for adults range from around 40% in a primary care practice to 70% in a speciality practice treating mainly severe asthma patients. Additional information on

4346-501: The City of Waycross from coming back into Pierce County. As of the 2020 United States census , there were 13,942 people, 5,748 households, and 3,197 families residing in the city. WXGA-TV , a Georgia Public Broadcasting outlet, is licensed to Waycross and also serves nearby Valdosta. Waycross is part of the Jacksonville, Florida television market. With over 100 employees and 10 physicians, Satilla Regional Medical Center

4428-585: The State's 13th state park. Waycross was the site of the 1948 Waycross B-29 crash , which led to the legal case United States v. Reynolds (1953), expanding the government's state secrets privilege. During the 1950s the city had a tourist gimmick: local police would stop motorists with out-of-state license plates and escort them to downtown Waycross. There they would be met by the Welcome World Committee and given overnight lodging, dinner and

4510-433: The U.S. could be attributed to these. The majority of the evidence does not support a causal role between paracetamol (acetaminophen) or antibiotic use and asthma. A 2014 systematic review found that the association between paracetamol use and asthma disappeared when respiratory infections were taken into account. Maternal psychological stress during pregnancy is a risk factor for the child to develop asthma. Asthma

4592-471: The age of 65, most people with obstructive airway disease will have asthma and COPD. In this setting, COPD can be differentiated by increased airway neutrophils, abnormally increased wall thickness, and increased smooth muscle in the bronchi. However, this level of investigation is not performed due to COPD and asthma sharing similar principles of management: corticosteroids, long-acting beta-agonists, and smoking cessation. It closely resembles asthma in symptoms,

4674-616: The airway obstruction in asthma is usually reversible; however, if left untreated, the chronic inflammation from asthma can lead the lungs to become irreversibly obstructed due to airway remodelling. In contrast to emphysema, asthma affects the bronchi, not the alveoli . The combination of asthma with a component of irreversible airway obstruction has been termed the asthma-chronic obstructive disease (COPD) overlap syndrome (ACOS) . Compared to other people with "pure" asthma or COPD, people with ACOS exhibit increased morbidity, mortality and possibly more comorbidities. An acute asthma exacerbation

4756-466: The airways include an increase in eosinophils and thickening of the lamina reticularis . Chronically the airways' smooth muscle may increase in size along with an increase in the numbers of mucous glands. Other cell types involved include T lymphocytes , macrophages , and neutrophils . There may also be involvement of other components of the immune system , including cytokines , chemokines , histamine , and leukotrienes among others. While asthma

4838-575: The battery of aeroallergens studied (the "missing antigen(s)" hypothesis). For example, an updated systematic review and meta-analysis of population-attributable risk (PAR) of Chlamydia pneumoniae biomarkers in chronic asthma found that the PAR for C. pneumoniae -specific IgE was 47%. Infectious asthma is an easily identified clinical presentation. When queried, asthma patients may report that their first asthma symptoms began after an acute lower respiratory tract illness. This type of history has been labelled

4920-498: The city of Jacksonville, Florida and the entire area of northeast Florida and southeast Georgia for many days. At times, the smoke reduced visibility to under a quarter of a mile and caused many health concerns. On May 22, 2007, from southern Georgia to Metro Atlanta , residents awoke to a blanket of smoke across the horizon. A strong smoke smell was very clear, and there were reports of people with irritated eyes, noses, and lungs. Some people with asthma were rushed to hospitals as

5002-530: The city wanted to take action to reduce the amount of human generated trash entering the Satilla River and ultimately the Atlantic Ocean . Georgia Governor Sonny Perdue said, "Water is one of Georgia's most important and precious resources... the litter trap installed by Waycross is a model of stewardship for the state and the nation." The Satilla River litter trap is the first in Georgia and only

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5084-431: The clinical prevalence of IA in adult-onset asthma is unavailable because clinicians are not trained to elicit this type of history routinely, and recollection in child-onset asthma is challenging. A population-based incident case-control study in a geographically defined area of Finland reported that 35.8% of new-onset asthma cases had experienced acute bronchitis or pneumonia in the year preceding asthma onset, representing

5166-421: The development of asthma, but exposure at an older age may provoke bronchoconstriction. Evidence supporting the hygiene hypothesis includes lower rates of asthma on farms and in households with pets. Use of antibiotics in early life has been linked to the development of asthma. Also, delivery via caesarean section is associated with an increased risk (estimated at 20–80%) of asthma – this increased risk

5248-546: The early morning. These episodes are usually associated with widespread but variable airflow obstruction within the lung that is often reversible either spontaneously or with treatment". There is currently no precise test for the diagnosis, which is typically based on the pattern of symptoms and response to therapy over time. Asthma may be suspected if there is a history of recurrent wheezing, coughing or difficulty breathing and these symptoms occur or worsen due to exercise, viral infections, allergens or air pollution. Spirometry

5330-455: The effectiveness of new medications. It may also be helpful in guiding treatment in those with acute exacerbations. Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in one second (FEV 1 ), and peak expiratory flow rate . Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic), based on whether symptoms are precipitated by allergens (atopic) or not (non-atopic). While asthma

5412-483: The end of May 564,450 acres (2,300 km) had burned. The Florida Folk Festival , the nation's oldest continuous festival, was cancelled for the first time because of the fire. (It was later rescheduled for November.) The major fire which entered from Georgia caused closures of Interstate 75 from the state line (and at times as far north as Valdosta ) to Interstate 10 . I-10 also had sections closed as well, sometimes as long as 40 mile (65 km). The detour by

5494-451: The home if a person has allergic symptoms to said pet. Dietary restrictions during pregnancy or when breastfeeding have not been found to be effective at preventing asthma in children and are not recommended. Omega-3 consumption, Mediterranean diet and antioxidants have been suggested by some studies to potentially help prevent crises but the evidence is still inconclusive. Reducing or eliminating compounds known to sensitive people from

5576-422: The number of lower respiratory infections . Other efforts that show promise include: limiting smoke exposure in utero , breastfeeding , and increased exposure to daycare or large families, but none are well supported enough to be recommended for this indication. Early pet exposure may be useful. Results from exposure to pets at other times are inconclusive and it is only recommended that pets be removed from

5658-525: The predicted best. Moderate is defined as between 80 and 200 L/min, or 25% and 50% of the predicted best, while severe is defined as ≤ 80 L/min, or ≤25% of the predicted best. Acute severe asthma , previously known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators and corticosteroids. Half of cases are due to infections with others caused by allergen, air pollution, or insufficient or inappropriate medication use. Brittle asthma

5740-504: The rates have increased significantly since the 1960s. Asthma was recognized as early as Ancient Egypt . The word asthma is from the Greek ἆσθμα , âsthma , which means 'panting'. Asthma is characterized by recurrent episodes of wheezing , shortness of breath , chest tightness , and coughing . Sputum may be produced from the lung by coughing but is often hard to bring up. During recovery from an asthma attack (exacerbation) ,

5822-562: The region from Tropical Storm Barry in June 2007. 31°11′28″N 82°30′36″W  /  31.191°N 82.510°W  / 31.191; -82.510 Waycross, Georgia Waycross is the county seat of, and only incorporated city in, Ware County in the U.S. state of Georgia . The population was 13,942 in the 2020 census . Waycross includes two historic districts ( Downtown Waycross Historic District and Waycross Historic District ) and several other properties that are on

5904-653: The risk of asthma with both having increased in recent years. Several factors may be at play including decreased respiratory function due to a buildup of fat and the fact that adipose tissue leads to a pro-inflammatory state. Beta blocker medications such as propranolol can trigger asthma in those who are susceptible. Cardioselective beta-blockers , however, appear safe in those with mild or moderate disease. Other medications that can cause problems in asthmatics are angiotensin-converting enzyme inhibitors , aspirin , and NSAIDs . Use of acid-suppressing medication ( proton pump inhibitors and H2 blockers ) during pregnancy

5986-550: The risk of developing asthma when acquired as young children. Certain other infections, however, may decrease the risk. The hygiene hypothesis attempts to explain the increased rates of asthma worldwide as a direct and unintended result of reduced exposure, during childhood, to non-pathogenic bacteria and viruses. It has been proposed that the reduced exposure to bacteria and viruses is due, in part, to increased cleanliness and decreased family size in modern societies. Exposure to bacterial endotoxin in early childhood may prevent

6068-626: The second Georgia city to do this. Georgia women would not get the right to vote generally in all elections until 1922. Waycross was home to Laura S. Walker (1861-1955) a noted author and conservationist . Walker promoted a comprehensive program of forestry activity, including the establishment of forest parks. She erected markers and monuments along old trails and at historic sites, in Waycross and Ware County so that local history would not be forgotten. An effort to recognize her work culminated in President Franklin D Roosevelt issuing

6150-537: The second in the nation. Part of Waycross was situated in Pierce County , but effective July 1, 2015, Waycross was no longer located nor allowed to be located in Pierce County. State Rep. Chad Nimmer introduced HB 523 during the 2015 Legislative Session without providing the required statutory notice to the City of Waycross. HB 523 de-annexed the portion of Waycross located in Pierce County and prevents

6232-692: The sputum may appear pus-like due to high levels of white blood cells called eosinophils . Symptoms are usually worse at night and in the early morning or in response to exercise or cold air. Some people with asthma rarely experience symptoms, usually in response to triggers, whereas others may react frequently and readily and experience persistent symptoms. A number of other health conditions occur more frequently in people with asthma, including gastroesophageal reflux disease (GERD), rhinosinusitis , and obstructive sleep apnea . Psychological disorders are also more common, with anxiety disorders occurring in between 16 and 52% and mood disorders in 14–41%. It

6314-424: The term asthma because there is lack of clinical data on inflammation in airways. In adults, COPD , congestive heart failure , airway masses, as well as drug-induced coughing due to ACE inhibitors may cause similar symptoms. In both populations vocal cord dysfunction may present similarly. Chronic obstructive pulmonary disease can coexist with asthma and can occur as a complication of chronic asthma. After

6396-413: The use of accessory muscles of respiration ( sternocleidomastoid and scalene muscles of the neck), there may be a paradoxical pulse (a pulse that is weaker during inhalation and stronger during exhalation), and over-inflation of the chest. A blue colour of the skin and nails may occur from lack of oxygen. In a mild exacerbation the peak expiratory flow rate (PEFR) is ≥200 L/min, or ≥50% of

6478-583: The workplace may be effective. It is not clear if annual influenza vaccinations affect the risk of exacerbations. Immunization, however, is recommended by the World Health Organization. Smoking bans are effective in decreasing exacerbations of asthma. While there is no cure for asthma, symptoms can typically be improved. The most effective treatment for asthma is identifying triggers, such as cigarette smoke , pets or other allergens, and eliminating exposure to them. If trigger avoidance

6560-441: Was bulldozed through the pine forest to protect the city of Waycross, but there were breaches of the line. The governor of Georgia made a disaster declaration , making Ware and Brantley counties eligible for government aid. Smoke closed several roads in the area, including U.S. 1 . By May 9, the main fire had consumed over 116,000 acres (469 km), mainly south of Waycross, east of Fargo and west of Folkston in

6642-502: Was incorporated as "Way Cross" on March 3, 1874. Waycross gets its name from the city's location at key railroad junctions; lines from six directions meet at the city. The city council in Waycross opened municipal primary elections to white women in 1917, the first town in Georgia to do so. This action was taken because some of the largest property owners in town were women who wanted a say in how their tax dollars were spent. It wasn't until two years later in 1919 that Atlanta became

6724-434: Was started by lightning at Bugaboo Island in the Okefenokee National Wildlife Refuge , and soon crept over the state line into Florida (and hence became the retronymed Bugaboo Scrub fire). It expanded extraordinarily quickly, combining with other fires that were already blazing in Georgia, and by May 16 had grown to 120,000 acres (490 km). By May 22 it had burned 475,000 acres (1,920 km) in Georgia and Florida. By

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