52-632: Kwong Wah Hospital is a 1,141-bed Charitable hospital in Yau Ma Tei , Hong Kong . Located on 25 Waterloo Road , Kwong Wah Hospital is the main district general hospital was founded by the Tung Wah Group in 1911, and managed by the Hospital Authority since 1991. It provides a full range of medical services to the population of West Kowloon and Wong Tai Sin. It is Kowloon Central Cluster 's major acute teaching hospital, and also
104-554: A "potential infectious source." The virus was also later found in raccoon dogs ( Nyctereuteus sp.), ferret badgers ( Melogale spp.), and domestic cats. In 2005, two studies identified a number of SARS-like coronaviruses in Chinese bats. Phylogenetic analysis of these viruses indicated a high probability that SARS coronavirus originated in bats and spread to humans either directly or through animals held in Chinese markets. The bats did not show any visible signs of disease, but are
156-697: A 64-year-old Chinese doctor who had treated cases of SARS in Guangdong arrived in Hong Kong to attend a wedding. He checked into the Metropole Hotel (the ninth floor - room 911). Although he had developed symptoms on 15 February, he felt well enough to travel, shop, and sight-see with his brother-in-law. On 22 February he sought urgent care at the Kwong Wah Hospital and was admitted to the intensive care unit. He died on 4 March. About 80% of
208-584: A Guangdong doctor who was treating patients at Sun Yat-Sen Memorial Hospital . He arrived in February and stayed on the ninth floor of the Metropole Hotel in Kowloon , infecting 16 of the hotel visitors. Those visitors traveled to Canada, Singapore, Taiwan, and Vietnam, spreading SARS to those locations. Another larger cluster of cases in Hong Kong centred on the Amoy Gardens housing estate. Its spread
260-496: A Neurosurgical and Antenatal Diagnosis referral centre. The Hospital has established various clinical centers, including Lai Kwok Wing Urology Centre, Minimally Invasive Surgery Training Centre and Chan Feng Men Ling Cardiac Centre. There are integrated Breast Centre and Dr Stephen Chow Chun-kay Assisted Reproduction Centre. It has established a Community Based Geriatric Service, Respiratory Care Unit, Acute Stroke Unit, TWGHs BOCHK Diabetes Centre, Wong Wha San Renal Memorial Centre, and
312-670: A Nuclear Medicine site. Kwong Wah Hospital is also a pioneer in Integrative Chinese and Western Medicine. TWGHs (Tung Wah Group of Hospitals) has established TWGHs Wilson T S Wang Integrated Chinese and Western Medicine Treatment Centre in Kwong Wah. The hospital has participated through joint consultation for designated diseases under protocols which developed by both Chinese Medicine and Western Medicine practitioners. The former Main Hall Building of Kwong Wah Hospital
364-576: A farmer from Shunde , Foshan , Guangdong, was treated in the First People's Hospital of Foshan. The patient died soon after, and no definite diagnosis was made on his cause of death. Despite taking some action to control it, Chinese government officials did not inform the World Health Organization of the outbreak until February 2003. This lack of openness caused delays in efforts to control the epidemic, resulting in criticism of
416-584: A flight to Singapore. The plane stopped in Hanoi , Vietnam, where the patient died in Hanoi French Hospital . Several of the medical staff who treated him soon developed the same disease despite basic hospital procedures. Italian doctor Carlo Urbani identified the threat and communicated it to WHO and the Vietnamese government; he later died from the disease. The severity of the symptoms and
468-770: A risk of side effects like arm pain, fever, and headache. According to research papers published in 2005 and 2006, the identification and development of novel vaccines and medicines to treat SARS was a priority for governments and public health agencies around the world. In early 2004, an early clinical trial on volunteers was planned. A major researcher's 2016 request, however, demonstrated that no field-ready SARS vaccine had been completed because likely market-driven priorities had ended funding. Several consequent reports from China on some recovered SARS patients showed severe long-time sequelae . The most typical diseases include, among other things, pulmonary fibrosis , osteoporosis , and femoral necrosis , which have led in some cases to
520-538: A second strain of SARS-CoV was identified: SARS-CoV-2 . This strain causes coronavirus disease 2019 ( COVID-19 ), the disease behind the COVID-19 pandemic . SARS produces flu-like symptoms which may include fever, muscle pain , lethargy , cough, sore throat , and other nonspecific symptoms . SARS often leads to shortness of breath and pneumonia , which may be direct viral pneumonia or secondary bacterial pneumonia . The average incubation period for SARS
572-609: Is a vaccine for SARS, although in March 2020 immunologist Anthony Fauci said the CDC developed one and placed it in the Strategic National Stockpile . That vaccine is a final product and field-ready as of March 2022. Clinical isolation and vaccination remain the most effective means to prevent the spread of SARS. Other preventive measures include: Many public health interventions were made to try to control
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#1732765288883624-541: Is common in people with SARS, the fecal–oral route does not appear to be a common mode of transmission. The basic reproduction number of SARS-CoV, R 0 , ranges from 2 to 4 depending on different analyses. Control measures introduced in April 2003 reduced the R to 0.4. SARS-CoV may be suspected in a patient who has: For a case to be considered probable, a chest X-ray must be indicative for atypical pneumonia or acute respiratory distress syndrome . The WHO has added
676-805: Is commonly used to treat SARS, there seems to have little to no effect on SARS-CoV, and no impact on patient's outcomes. There is currently no proven antiviral therapy. Tested substances, include ribavirin , lopinavir , ritonavir , type I interferon , that have thus far shown no conclusive contribution to the disease's course. Administration of corticosteroids , is recommended by the British Thoracic Society / British Infection Society / Health Protection Agency in patients with severe disease and O2 saturation of <90%. People with SARS-CoV must be isolated, preferably in negative-pressure rooms , with complete barrier nursing precautions taken for any necessary contact with these patients, to limit
728-433: Is four to six days, although it is rarely as short as one day or as long as 14 days. The primary route of transmission for SARS-CoV is contact of the mucous membranes with respiratory droplets or fomites . As with all respiratory pathogens once presumed to transmit via respiratory droplets, it is highly likely to be carried by the aerosols generated during routine breathing, talking, and even singing. While diarrhea
780-695: Is preserved and houses the Tung Wah Group of Hospitals Museum . Since 1898, after the lease of the New Territories and its incorporation into British Hong Kong , the Han Chinese population living in Kowloon increased rapidly. However, there were no hospitals in Kowloon or the New Territories, patients who require hospital care would have to ferry across to Hong Kong Island . Chinese philanthropists and physicians, led by Kai Ho , proposed
832-412: Is suspected to have been facilitated by defects in its bathroom drainage system that allowed sewer gases including virus particles to vent into the room. Bathroom fans exhausted the gases and wind carried the contagion to adjacent downwind complexes. Concerned citizens in Hong Kong worried that information was not reaching people quickly enough and created a website called sosick.org, which eventually forced
884-495: The Hong Kong cases have been traced back to this doctor. On 25 February, the 53-year-old brother-in-law of the Guangdong doctor came to the Kwong Wah Hospital. He was not admitted that day but his illness worsened, and he was admitted on 1 March. He died on 19 March. 24-Hour Accident and Emergency Service Kwong Wah Hospital is also provides integrative traditional Chinese medicine (TCM) and Western Medicine. TWGHs Wilson T S Wang Integrated Chinese and Western Medicine Treatment Centre
936-457: The Hong Kong government to provide information related to SARS in a timely manner. The first cohort of affected people were discharged from hospital on 29 March 2003. The first case of SARS in Toronto was identified on 23 February 2003. Beginning with an elderly woman, Kwan Sui-Chu, who had returned from a trip to Hong Kong and died on 5 March, the virus eventually infected 257 individuals in
988-605: The Kowloon area, in contrast to Hong Kong Island. In 1928, local Chinese leaders convinced the Yau Ma Tei Tin Hau Temple , at the time another important local charity, to transfer its assets to the Kwong Wah Hospital. In 1931, the three hospitals managed separately by the board of the Tung Wah Hospital were reorganized into the Tung Wah Group of Hospitals . With the rapid development of Kowloon after World War II, funding from both local charities and
1040-424: The Kwong Wah Hospital. Integrated Chinese medical treatment continue to be available to this day. Like its sister hospital the Tung Wah Hospital , the hospital initially relied on support from local charitable organizations, providing medicine and medical services free of charge to local residents. The hospital ran into funding shortages in its early days due to the relatively low number of wealthy citizens living in
1092-699: The People's Republic of China from the international community. China officially apologized for early slowness in dealing with the SARS epidemic. In 2003, when the virus broke out in China, a 72 year old with SARS infected multiple people on board an Air China Boeing 737 , causing 5 deaths. The viral outbreak was subsequently genetically traced to a colony of cave-dwelling horseshoe bats in Xiyang Yi Ethnic Township , Yunnan. The outbreak first came to
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#17327652888831144-528: The SARS genome in April 2003. Scientists at Erasmus University in Rotterdam , the Netherlands demonstrated that the SARS coronavirus fulfilled Koch's postulates thereby suggesting it as the causative agent. In the experiments, macaques infected with the virus developed the same symptoms as human SARS patients. In late May 2003, a study was conducted using samples of wild animals sold as food in
1196-652: The United States and are usually funded through donations and special contributions from partnering affiliates. This hospital-related article is a stub . You can help Misplaced Pages by expanding it . SARS Severe acute respiratory syndrome ( SARS ) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1 , the first identified strain of the SARS-related coronavirus . The first known cases occurred in November 2002, and
1248-461: The age group of the patient. Patients under 24 were least likely to die (less than 1%); those 65 and older were most likely to die (over 55%). As with MERS and COVID-19 , SARS resulted in significantly more deaths of males than females. The SARS epidemic began in the Guangdong province of China in November 2002. The earliest case developed symptoms on 16 November 2002. The index patient ,
1300-570: The attention of the international medical community on 27 November 2002, when Canada's Global Public Health Intelligence Network (GPHIN), an electronic warning system that is part of the World Health Organization's Global Outbreak Alert and Response Network (GOARN), picked up reports of a "flu outbreak" in China through Internet media monitoring and analysis and sent them to the WHO. While GPHIN's capability had recently been upgraded to enable Arabic, Chinese, English, French, Russian, and Spanish translation,
1352-489: The category of "laboratory confirmed SARS" which means patients who would otherwise be considered "probable" and have tested positive for SARS based on one of the approved tests ( ELISA , immunofluorescence or PCR ) but whose chest X-ray findings do not show SARS-CoV infection (e.g. ground glass opacities, patchy consolidations unilateral). The appearance of SARS-CoV in chest X-rays is not always uniform but generally appears as an abnormality with patchy infiltrates. There
1404-434: The chances of getting sick up to 80% compared to no mask. A screening process was also put in place at airports to monitor air travel to and from affected countries. SARS-CoV is most infectious in severely ill patients, which usually occurs during the second week of illness. This delayed infectious period meant that quarantine was highly effective; people who were isolated before day five of their illness rarely transmitted
1456-415: The chances of medical personnel becoming infected. In certain cases, natural ventilation by opening doors and windows is documented to help decreasing indoor concentration of virus particles. Some of the more serious damage caused by SARS may be due to the body's own immune system reacting in what is known as cytokine storm . Vaccines can help the immune system to create enough antibodies and decrease
1508-540: The complete loss of working ability or even self-care ability of people who have recovered from SARS. As a result of quarantine procedures, some of the post-SARS patients have been diagnosed with post-traumatic stress disorder (PTSD) and major depressive disorder . SARS was a relatively rare disease; at the end of the epidemic in June 2003, the incidence was 8,422 cases with a case fatality rate (CFR) of 11%. The case fatality rate (CFR) ranges from 0% to 50% depending on
1560-537: The danger to China, there appeared to be a change in official policy when SARS began to receive a much greater prominence in the official media. Some have directly attributed this to the death of an American teacher, James Earl Salisbury , in Hong Kong. It was around this same time that Jiang Yanyong made accusations regarding the undercounting of cases in Beijing military hospitals. After intense pressure, Chinese officials allowed international officials to investigate
1612-491: The disease to others. As of 2017, the CDC was still working to make federal and local rapid-response guidelines and recommendations in the event of a reappearance of the virus. As SARS is a viral disease, antibiotics do not have direct effect but may be used against bacterial secondary infection. Treatment of SARS is mainly supportive with antipyretics , supplemental oxygen and mechanical ventilation as needed. While ribavirin
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1664-506: The early pace of the epidemic. He subsequently contracted the disease himself, and died in March 2003. Malik Peiris and his colleagues became the first to isolate the virus that causes SARS, a novel coronavirus now known as SARS-CoV-1 . By June 2003, Peiris, together with his long-time collaborators Leo Poon and Guan Yi , has developed a rapid diagnostic test for SARS-CoV-1 using real-time polymerase chain reaction . The CDC and Canada's National Microbiology Laboratory identified
1716-464: The end of June 2003. The official response by the Ontario provincial government and Canadian federal government has been widely criticized in the years following the outbreak. Brian Schwartz, vice-chair of Ontario's SARS Scientific Advisory Committee, described public health officials' preparedness and emergency response at the time of the outbreak as "very, very basic and minimal at best". Critics of
1768-425: The establishment of a charitable hospital to serve the growing Chinese population in the Kowloon area; the hospital's name ( Kwong Wah , Guangdong Han Chinese ) reflects its mission. The Hong Kong government eventually took up the proposal in 1907 and contributed $ 139,340 (equivalent to approximately $ 6 million HKD today) over five years, with the assistance of local charitable organizations, to finish construction of
1820-472: The government has increased significantly, and the hospital has experienced over a dozen reconstruction and expansion projects, developing from a single building of 72 beds initially to its modern-day complex of seven towers with several thousand hospital beds. The hospital played a major role in the SARS epidemic which made its way from Guangdong province to Hong Kong early in 2003. On 21 February, Liu Jianlun,
1872-498: The hospital. The opening ceremony occurred in October 1911. Kwong Wah Hospital was managed by the board of directors of the Tung Wah Hospital . At the time, much of the Chinese population was skeptical of Western medicine and some even refused Western treatment on their deathbeds; however, the repeated invasion of the bubonic plague due to globalized trade meant that the Hong Kong government and local physicians were acutely aware of
1924-673: The infection among hospital staff alarmed global health authorities, who were fearful of another emergent pneumonia epidemic. On 12 March 2003, the WHO issued a global alert , followed by a health alert by the United States Centers for Disease Control and Prevention (CDC). Local transmission of SARS took place in Toronto , Ottawa, San Francisco, Ulaanbaatar , Manila , Singapore, Taiwan, Hanoi and Hong Kong whereas within China it spread to Guangdong, Jilin , Hebei, Hubei , Shaanxi, Jiangsu , Shanxi, Tianjin , and Inner Mongolia . The disease spread in Hong Kong from Liu Jianlun,
1976-565: The likely natural reservoirs of SARS-like coronaviruses. In late 2006, scientists from the Chinese Centre for Disease Control and Prevention of Hong Kong University and the Guangzhou Centre for Disease Control and Prevention established a genetic link between the SARS coronavirus appearing in civets and in the second, 2004 human outbreak, bearing out claims that the disease had jumped across species. It took 14 years to find
2028-551: The local market in Guangdong, China. The study found that "SARS-like" coronaviruses could be isolated from masked palm civets ( Paguma sp.). Genomic sequencing determined that these animal viruses were very similar to human SARS viruses, however they were phylogenetically distinct, and so the study concluded that it was unclear whether they were the natural reservoir in the wild. Still, more than 10,000 masked palm civets were killed in Guangdong Province since they were
2080-437: The need to introduce modern Western medicine to the wider population. The Tung Wah hospitals attempted a compromise of adapting from the scientific knowledge and effective methods of Western medicine while also providing traditional Chinese medical care, often as a form of placebo . In 1922, local philanthropists donated $ 50,580 HKD (equivalent to approximately $ 2 million HKD today) to set up a specialist Chinese medicine clinic at
2132-418: The original bat population likely responsible for the SARS pandemic. In December 2017, "after years of searching across China, where the disease first emerged, researchers reported ... that they had found a remote cave in Xiyang Yi Ethnic Township , Yunnan province, which is home to horseshoe bats that carry a strain of a particular virus known as a coronavirus. This strain has all the genetic building blocks of
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2184-607: The province of Ontario. The trajectory of this outbreak is typically divided into two phases, the first centring around her son Tse Chi Kwai, who infected other patients at the Scarborough Grace Hospital and died on 13 March. The second major wave of cases was clustered around accidental exposure among patients, visitors, and staff within the North York General Hospital . The WHO officially removed Toronto from its list of infected areas by
2236-440: The response often cite poorly outlined and enforced protocol for protecting healthcare workers and identifying infected patients as a major contributing factor to the continued spread of the virus. The atmosphere of fear and uncertainty surrounding the outbreak resulted in staffing issues in area hospitals when healthcare workers elected to resign rather than risk exposure to SARS. In late February 2003, Italian doctor Carlo Urbani
2288-540: The situation there. This revealed problems plaguing the aging mainland Chinese healthcare system, including increasing decentralization, red tape , and inadequate communication. Many healthcare workers in the affected nations risked their lives and died by treating patients, and trying to contain the infection before ways to prevent infection were known. The epidemic reached the public spotlight in February 2003, when an American businessman traveling from China, Johnny Chen, became affected by pneumonia-like symptoms while on
2340-507: The spread of the disease, which is mainly spread through respiratory droplets in the air, either inhaled or deposited on surfaces and subsequently transferred to a body's mucous membranes. These interventions included earlier detection of the disease; isolation of people who are infected; droplet and contact precautions; and the use of personal protective equipment (PPE), including masks and isolation gowns. A 2017 meta-analysis found that for medical professionals wearing N-95 masks could reduce
2392-462: The syndrome caused the 2002–2004 SARS outbreak . In the 2010s, Chinese scientists traced the virus through the intermediary of Asian palm civets to cave-dwelling horseshoe bats in Xiyang Yi Ethnic Township , Yunnan . SARS was a relatively rare disease; at the end of the epidemic in June 2003, the incidence was 8,422 cases with a case fatality rate (CFR) of 11%. No cases of SARS-CoV-1 have been reported worldwide since 2004. In December 2019,
2444-592: The system was limited to English or French in presenting this information. Thus, while the first reports of an unusual outbreak were in Chinese, an English report was not generated until 21 January 2003. The first super-spreader was admitted to the Sun Yat-sen Memorial Hospital in Guangzhou on 31 January, which soon spread the disease to nearby hospitals. In early April 2003, after a prominent physician, Jiang Yanyong , pushed to report
2496-540: The type that triggered the global outbreak of SARS in 2002." The research was performed by Shi Zhengli , Cui Jie, and co-workers at the Wuhan Institute of Virology , China, and published in PLOS Pathogens . The authors are quoted as stating that "another deadly outbreak of SARS could emerge at any time. The cave where they discovered their strain is only a kilometre from the nearest village." The virus
2548-563: Was achieved through successful public health measures. In the following months, four SARS cases were reported in China between December 2003 and January 2004. While SARS-CoV-1 probably persists as a potential zoonotic threat in its original animal reservoir, human-to-human transmission of this virus may be considered eradicated because no human case has been documented since four minor, brief, subsequent outbreaks in 2004. After containment, there were four laboratory accidents that resulted in infections. Study of live SARS specimens requires
2600-485: Was called into The French Hospital of Hanoi to look at Johnny Chen, an American businessman who had fallen ill with what doctors thought was a bad case of influenza . Urbani realized that Chen's ailment was probably a new and highly contagious disease. He immediately notified the WHO. He also persuaded the Vietnamese Health Ministry to begin isolating patients and screening travelers, thus slowing
2652-569: Was ephemeral and seasonal in bats. In 2019, a similar virus to SARS caused a cluster of infections in Wuhan , eventually leading to the COVID-19 pandemic. A small number of cats and dogs tested positive for the virus during the outbreak. However, these animals did not transmit the virus to other animals of the same species or to humans. The World Health Organization declared severe acute respiratory syndrome contained on 5 July 2003. The containment
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#17327652888832704-700: Was established by the TWGHs in Kwong Wah Hospital . Through joint consultation for designated diseases under protocols which developed by both Chinese Medicine and Western Medicine practitioners. MTR Kwun Tong line and Tsuen Wan line Yau Ma Tei station Exit A2. Charitable hospital A charitable hospital , or charity hospital , is a non-profit hospital that provides treatment for poor and uninsured people who can not purchase treatment. An example would be St. Jude Children's Hospital that provides assistance to children and funds research for pediatric ailments. Charitable hospitals are usually tax exempt in
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