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The New England Journal of Medicine ( NEJM ) is a weekly medical journal published by the Massachusetts Medical Society . Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. Its 2023 impact factor was 96.2, ranking it 2nd out of 168 journals in the category "Medicine, General & Internal".

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85-623: In September 1811, Boston physician John Collins Warren , along with James Jackson, submitted a formal prospectus to establish the New England Journal of Medicine and Surgery and Collateral Branches of Science as a medical and philosophical journal. Subsequently, the first issue of the New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science was published in January 1812. The journal

170-490: A cannon barrage for two hours, but their shot could not reach the colonists' cannons at such a height. The British gave up, boarded their ships, and sailed away. This has become known as " Evacuation Day ", which Boston still celebrates each year on March 17. After this, Washington was so impressed that he made Rufus Putnam his chief engineer. After the Revolution, Boston's long seafaring tradition helped make it one of

255-529: A global leader in higher education and research and the largest biotechnology hub in the world. The city is also a national leader in scientific research, law, medicine, engineering, and business. With nearly 5,000 startup companies, the city is considered a global pioneer in innovation and entrepreneurship , and more recently in artificial intelligence . Boston's economy also includes finance , professional and business services, information technology , and government activities. Boston households provide

340-624: A lively port , and the then-town primarily engaged in shipping and fishing during its colonial days. Boston was a primary stop on a Caribbean trade route and imported large amounts of molasses, which led to the creation of Boston baked beans . Boston's economy stagnated in the decades prior to the Revolution. By the mid-18th century, New York City and Philadelphia had surpassed Boston in wealth. During this period, Boston encountered financial difficulties even as other cities in New England grew rapidly. The weather continuing boisterous

425-501: A million residents, and the most densely populated state capital. Some 1.2 million persons may be within Boston's boundaries during work hours, and as many as 2 million during special events. This fluctuation of people is caused by hundreds of thousands of suburban residents who travel to the city for work, education, health care, and special events. Editorial An editorial , or leading article (UK) or leader (UK),

510-480: A new sub-journal, NEJM Evidence . NEJM Evidence is a monthly digital journal featuring original research. It focuses on clinical trials and decision making. The New England Journal of Medicine requires that articles it publishes have not been published or released elsewhere. Referred to as the Ingelfinger rule , the policy is intended to protect newsworthiness, and to subject research to peer review "before it

595-475: A pair of bombs near the finish line of the Boston Marathon , killing three people and injuring roughly 264. The subsequent search for the bombers led to a lock-down of Boston and surrounding municipalities. The region showed solidarity during this time as symbolized by the slogan Boston Strong . In 2016, Boston briefly shouldered a bid as the U.S. applicant for the 2024 Summer Olympics . The bid

680-538: A port, manufacturing hub, and center for education and culture. The city also expanded significantly beyond the original peninsula by filling in land and annexing neighboring towns. Boston's many firsts include the United States' first public park ( Boston Common , 1634), the first public school ( Boston Latin School , 1635), and the first subway system ( Tremont Street subway , 1897). Boston has emerged as

765-565: A project to improve the historic West End neighborhood. Extensive demolition was met with strong public opposition, and thousands of families were displaced. The BRA continued implementing eminent domain projects, including the clearance of the vibrant Scollay Square area for construction of the modernist style Government Center . In 1965, the Columbia Point Health Center opened in the Dorchester neighborhood,

850-401: A violent tornado , the city itself has experienced many tornado warnings . Damaging storms are more common to areas north, west, and northwest of the city. See or edit raw graph data . In 2020, Boston was estimated to have 691,531 residents living in 266,724 households —a 12% population increase over 2010. The city is the third-most densely populated large U.S. city of over half

935-505: Is 2 °F (−17 °C) on December 30, 1917, while the record warm daily minimum is 83 °F (28 °C) on both August 2, 1975 and July 21, 2019. Boston averages 43.6 in (1,110 mm) of precipitation a year, with 49.2 in (125 cm) of snowfall per season. Most snowfall occurs from mid-November through early April, and snow is rare in May and October. There is also high year-to-year variability in snowfall; for instance,

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1020-508: Is July, with a mean temperature of 74.1 °F (23.4 °C). The coldest month is January, with a mean temperature of 29.9 °F (−1.2 °C). Periods exceeding 90 °F (32 °C) in summer and below freezing in winter are not uncommon but tend to be fairly short, with about 13 and 25 days per year seeing each, respectively. Sub- 0 °F (−18 °C) readings usually occur every 3 to 5 years. The most recent sub- 0 °F (−18 °C) reading occurred on February 4, 2023, when

1105-424: Is an article or any other written document, often unsigned, written by the senior editorial people or publisher of a newspaper or magazine , that expresses the author(s)'s opinion about a particular topic or issue. Australian and major United States newspapers, such as The New York Times and The Boston Globe , often classify editorials under the heading " opinion ". Illustrated editorials may appear in

1190-547: Is an intellectual, technological, and political center. However, it has lost some important regional institutions, including the loss to mergers and acquisitions of local financial institutions such as FleetBoston Financial , which was acquired by Charlotte -based Bank of America in 2004. Boston-based department stores Jordan Marsh and Filene's have both merged into the New York City –based Macy's . The 1993 acquisition of The Boston Globe by The New York Times

1275-588: Is in Roxbury . Due north of the center we find the South End. This is not to be confused with South Boston which lies directly east from the South End. North of South Boston is East Boston and southwest of East Boston is the North End Unknown, A local colloquialism Boston has an area of 89.63 sq mi (232.1 km ). Of this area, 48.4 sq mi (125.4 km ), or 54%, of it

1360-410: Is land and 41.2 sq mi (106.7 km ), or 46%, of it is water. The city's elevation, as measured at Logan International Airport , is 19 ft (5.8 m) above sea level . The highest point in Boston is Bellevue Hill at 330 ft (100 m) above sea level, and the lowest point is at sea level. The city is adjacent to Boston Harbor , an arm of Massachusetts Bay , and by extension,

1445-442: Is touted to the public or the profession". By 1991, four types of exceptions were recognized, including when "prepublication release of research conclusions is warranted because of immediate implications for the public health". The rule was first described in a 1969 editorial , "Definition of Sole Contribution", by Franz Ingelfinger , the editor-in-chief at that time. A number of medical journals have similar rules in place. In

1530-552: Is unwarranted. In False Positive: A Year of Error, Omission, and Political Correctness in the New England Journal of Medicine , he examines various articles on medical and social issues that the NEJM published over the course of a year. He found that many arrived at conclusions which were not supported by the evidence presented, or ignored easily available evidence that contradicted their conclusions. In 2022, NEJM set up

1615-508: The Arbella ) and John Cotton (grandfather of Cotton Mather ) had emigrated to New England . The name of the English town ultimately derives from its patron saint, St. Botolph , in whose church John Cotton served as the rector until his emigration with Johnson. In early sources, Lincolnshire's Boston was known as "St. Botolph's town", later contracted to "Boston". Before this renaming,

1700-815: The American Revolution occurred in or near Boston. The then-town's mob presence, along with the colonists' growing lack of faith in either Britain or its Parliament , fostered a revolutionary spirit there. When the British parliament passed the Stamp Act in 1765, a Boston mob ravaged the homes of Andrew Oliver , the official tasked with enforcing the Act, and Thomas Hutchinson , then the Lieutenant Governor of Massachusetts. The British sent two regiments to Boston in 1768 in an attempt to quell

1785-653: The American Revolution , Boston was home to several events that proved central to the revolution and subsequent Revolutionary War , including the Boston Massacre (1770), the Boston Tea Party (1773), Paul Revere's Midnight Ride (1775), the Battle of Bunker Hill (1775), and the Siege of Boston (1775–1776). Following American independence from Great Britain , the city continued to play an important role as

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1870-585: The Boston Garden opening in 1928. Logan International Airport opened on September 8, 1923. Boston went into decline by the early to mid-20th century, as factories became old and obsolete and businesses moved out of the region for cheaper labor elsewhere. Boston responded by initiating various urban renewal projects, under the direction of the Boston Redevelopment Authority (BRA) established in 1957. In 1958, BRA initiated

1955-561: The Boston Medical Intelligencer , 1828 for the Boston Medical and Surgical Journal , and 1928 for the New England Journal of Medicine . Notable articles from the course of The New England Journal of Medicine 's history include: On April 25, 1996, the NEJM announced a new web site, which published each week the abstracts for research articles and the full text of editorials, cases, and letters to

2040-625: The Boston Public Library , Trinity Church, single-family homes and wooden/brick multi-family row houses. The South End Historic District is the largest surviving contiguous Victorian-era neighborhood in the US. The geography of downtown and South Boston was particularly affected by the Central Artery/Tunnel Project (which ran from 1991 to 2007, and was known unofficially as the " Big Dig "). That project removed

2125-559: The Massachusetts Bay Colony and was signed by its first governor John Winthrop . Puritan ethics and their focus on education also influenced the early history of the city. America's first public school, Boston Latin School , was founded in Boston in 1635. Boston was the largest town in the Thirteen Colonies until Philadelphia outgrew it in the mid-18th century. Boston's oceanfront location made it

2210-537: The North End , and the Seaport . Boston is sometimes called a "city of neighborhoods" because of the profusion of diverse subsections. The city government's Office of Neighborhood Services has officially designated 23 neighborhoods: More than two-thirds of inner Boston's modern land area did not exist when the city was founded. Instead, it was created via the gradual filling in of the surrounding tidal areas over

2295-652: The South End , the West End , the Financial District , and Chinatown . After the Great Boston fire of 1872 , workers used building rubble as landfill along the downtown waterfront. During the mid-to-late 19th century, workers filled almost 600 acres (240 ha) of brackish Charles River marshlands west of Boston Common with gravel brought by rail from the hills of Needham Heights. The city annexed

2380-412: The 1970s, the city's economy had begun to recover after 30 years of economic downturn. A large number of high-rises were constructed in the Financial District and in Boston's Back Bay during this period. This boom continued into the mid-1980s and resumed after a few pauses. Hospitals such as Massachusetts General Hospital , Beth Israel Deaconess Medical Center , and Brigham and Women's Hospital lead

2465-457: The 19th century, Boston's core neighborhoods had become enclaves of ethnically distinct immigrants with their residence yielding lasting cultural change. Italians became the largest inhabitants of the North End , Irish dominated South Boston and Charlestown , and Russian Jews lived in the West End . Irish and Italian immigrants brought with them Roman Catholicism. Currently, Catholics make up Boston's largest religious community, and

2550-643: The 20th century: Horticultural Hall , the Tennis and Racquet Club , Isabella Stewart Gardner Museum , Fenway Studios , Jordan Hall , and the Boston Opera House .  The Longfellow Bridge , built in 1906, was mentioned by Robert McCloskey in Make Way for Ducklings , describing its "salt and pepper shakers" feature. Fenway Park , home of the Boston Red Sox , opened in 1912, with

2635-598: The Atlantic Ocean. Boston is surrounded by the Greater Boston metropolitan region. It is bordered to the east by the town of Winthrop and the Boston Harbor Islands , to the northeast by the cities of Revere , Chelsea and Everett , to the north by the cities of Somerville and Cambridge , to the northwest by Watertown , to the west by the city of Newton and town of Brookline , to

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2720-551: The Author Accepted Manuscript that may be deposited in a noncommercial repository after publication. NEJM also has two podcast features, one with interviews of doctors and researchers that are publishing in the journal, and another summarizing the content of each issue. Other offerings include Continuing Medical Education, Videos in Clinical Medicine (showing videos of medical procedures), and

2805-512: The Irish have played a major role in Boston politics since the early 20th century; prominent figures include the Kennedys , Tip O'Neill , and John F. Fitzgerald . Between 1631 and 1890, the city tripled its area through land reclamation by filling in marshes, mud flats, and gaps between wharves along the waterfront. Reclamation projects in the middle of the century created significant parts of

2890-579: The John Hancock Tower is the old John Hancock Building with its prominent illuminated beacon , the color of which forecasts the weather. Downtown and its immediate surroundings (including the Financial District, Government Center, and South Boston ) consist largely of low-rise masonry buildings – often federal style and Greek revival – interspersed with modern high-rises. Back Bay includes many prominent landmarks, such as

2975-614: The Massachusetts Medical Society purchased the Journal for US$ 1 (equivalent to $ 17 in 2023) and, in 1928, renamed it to The New England Journal of Medicine . The journal's logo depicts the snake-wrapped Rod of Asclepius crossed over a quill pen. The dates on the logo represent the founding of the components of The New England Journal of Medicine : 1812 for the New England Journal of Medicine and Surgery and Collateral Branches of Medical Science , 1823 for

3060-563: The Native people, as many had died of European diseases brought by early settlers and traders. Archaeological excavations unearthed one of the oldest fishweirs in New England on Boylston Street , which Native people constructed as early as 7,000 years before European arrival in the Western Hemisphere. The first European to live in what would become Boston was a Cambridge -educated Anglican cleric named William Blaxton . He

3145-735: The Renew Boston Whole Building Incentive which reduces the cost of living in buildings that are deemed energy efficient. Under the Köppen climate classification , Boston has either a hot-summer humid continental climate (Köppen Dfa ) under the 0 °C (32.0 °F) isotherm or a humid subtropical climate (Köppen Cfa ) under the −3 °C (26.6 °F) isotherm. Summers are warm to hot and humid, while winters are cold and stormy, with occasional periods of heavy snow. Spring and fall are usually cool and mild, with varying conditions dependent on wind direction and

3230-403: The U.S. government, including NIH, to ensure that authors are able to meet their funders’ requirements for public access to research results. For research articles submitted before February 1, 2024, NEJM makes the full-text Version of Record available at NEJM.org six months after publication. For research articles submitted on or after February 1, 2024, NEJM will provide authors with a PDF file of

3315-595: The Vioxx litigation and made available to the Journal, that at least two of the authors knew about the three additional myocardial infarctions at least two weeks before the authors submitted the first of two revisions and 4 1/2 months before publication of the article." During the five-year period between publication and Expression of Concern, it has been estimated that Merck paid NEJM as much as US$ 836,000 for article reprints that Merck used for promotional purposes. The journal

3400-615: The act as an attempt to force them to accept the taxes established by the Townshend Acts . The act prompted the Boston Tea Party , where a group of angered Bostonians threw an entire shipment of tea sent by the East India Company into Boston Harbor . The Boston Tea Party was a key event leading up to the revolution, as the British government responded furiously with the Coercive Acts , demanding compensation for

3485-535: The adjacent towns of South Boston (1804), East Boston (1836), Roxbury (1868), Dorchester (including present-day Mattapan and a portion of South Boston ) (1870), Brighton (including present-day Allston ) (1874), West Roxbury (including present-day Jamaica Plain and Roslindale ) (1874), Charlestown (1874), and Hyde Park (1912). Other proposals were unsuccessful for the annexation of Brookline , Cambridge, and Chelsea . Many architecturally significant buildings were built during these early years of

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3570-508: The angry colonists. This did not sit well with the colonists, however. In 1770, during the Boston Massacre , British troops shot into a crowd that had started to violently harass them. The colonists compelled the British to withdraw their troops. The event was widely publicized and fueled a revolutionary movement in America. In 1773, Parliament passed the Tea Act . Many of the colonists saw

3655-426: The area. Nevertheless, the city experienced conflict starting in 1974 over desegregation busing , which resulted in unrest and violence around public schools throughout the mid-1970s. Boston has also experienced gentrification in the latter half of the 20th century, with housing prices increasing sharply since the 1990s when the city's rent control regime was struck down by statewide ballot proposition . Boston

3740-478: The authors knew more about certain adverse events than they disclosed at the time of publication. From the Expression of Concern: "Until the end of November 2005, we believed that these were late events that were not known to the authors in time to be included in the article published in the Journal on November 23, 2000. It now appears, however, from a memorandum dated July 5, 2000, that was obtained by subpoena in

3825-605: The centuries. This was accomplished using earth from the leveling or lowering of Boston's three original hills (the "Trimountain", after which Tremont Street is named), as well as with gravel brought by train from Needham to fill the Back Bay . Christian Science Center , Copley Square , Newbury Street , and New England's two tallest buildings: the John Hancock Tower and the Prudential Center . Near

3910-460: The city government. A climate action plan from 2019 anticipates 2 ft (1 m) to more than 7 ft (2 m) of sea-level rise in Boston by the end of the 21st century. Many older buildings in certain areas of Boston are supported by wooden piles driven into the area's fill; these piles remain sound if submerged in water, but are subject to dry rot if exposed to air for long periods. Groundwater levels have been dropping in many areas of

3995-464: The city often receives sea breezes , especially in the late spring, when water temperatures are still quite cold and temperatures at the coast can be more than 20 °F (11 °C) colder than a few miles inland, sometimes dropping by that amount near midday. Thunderstorms typically occur from May to September; occasionally, they can become severe, with large hail , damaging winds, and heavy downpours. Although downtown Boston has never been struck by

4080-443: The city's economy, and the city's industrial manufacturing overtook international trade in economic importance by the mid-19th century. The small rivers bordering the city and connecting it to the surrounding region facilitated shipment of goods and led to a proliferation of mills and factories. Later, a dense network of railroads furthered the region's industry and commerce. During this period, Boston flourished culturally as well. It

4165-414: The city, due in part to an increase in the amount of rainwater discharged directly into sewers rather than absorbed by the ground. The Boston Groundwater Trust coordinates monitoring groundwater levels throughout the city via a network of public and private monitoring wells. The city developed a climate action plan covering carbon reduction in buildings, transportation, and energy use. The first such plan

4250-474: The commander-in-chief of the British forces in North America, led the British army in the siege. On June 17, the British captured Charlestown (now part of Boston) during the Battle of Bunker Hill . The British army outnumbered the militia stationed there, but it was a pyrrhic victory for the British because their army suffered irreplaceable casualties. It was also a testament to the skill and training of

4335-664: The destroyed tea from the Bostonians. This angered the colonists further and led to the American Revolutionary War . The war began in the area surrounding Boston with the Battles of Lexington and Concord . Boston itself was besieged for almost a year during the siege of Boston , which began on April 19, 1775. The New England militia impeded the movement of the British Army . Sir William Howe , then

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4420-544: The early 2000s, The New England Journal of Medicine was involved in a controversy around problems with research on the drug Vioxx . A study was published in the journal in November 2000 which noted an increase in myocardial infarction amongst those taking Vioxx. According to Richard Smith , the former editor of the British Medical Journal , concerns about the correctness of that study were raised with

4505-552: The editor. After print publishing for 184 years this was the NEJM ' s first use of the Internet for electronic publication. The site was launched several months earlier in 1996, but the editors wanted proof that weekly electronic publication would work. Only then was an announcement approved for publication on the editorial page. In 1997, the website included prepublication releases of certain articles prior to their print publication. In 1998, online publication extended to include

4590-466: The elevated Central Artery and incorporated new green spaces and open areas. Boston is located within the Boston Basin ecoregion , which is characterized by low and rolling hills with a number of ponds, lakes, and reservoirs. Forests are mainly transition hardwoods such as oak - hickory mixed with white pine . As a coastal city built largely on fill , sea-level rise is of major concern to

4675-541: The first Community Health Center in the United States. It mostly served the massive Columbia Point public housing complex adjoining it, which was built in 1953. The health center is still in operation and was rededicated in 1990 as the Geiger-Gibson Community Health Center. The Columbia Point complex itself was redeveloped and revitalized from 1984 to 1990 into a mixed-income residential development called Harbor Point Apartments. By

4760-461: The first wave of European immigrants . Irish immigrants dominated the first wave of newcomers during this period, especially following the Great Famine ; by 1850, about 35,000 Irish lived in Boston . In the latter half of the 19th century, the city saw increasing numbers of Irish, Germans , Lebanese , Syrians, French Canadians , and Russian and Polish Jews settling there. By the end of

4845-433: The form of editorial cartoons . Typically, a newspaper's editorial board evaluates which issues are important for their readership to know the newspaper's opinion on. Editorials are typically published on a dedicated page, called the editorial page, which often features letters to the editor from members of the public; the page opposite this page is called the op-ed page and frequently contains opinion pieces (hence

4930-461: The fortifications and dozens of cannons on Dorchester Heights that Henry Knox had laboriously brought through the snow from Fort Ticonderoga . The astonished British awoke the next morning to see a large array of cannons bearing down on them. General Howe is believed to have said that the Americans had done more in one night than his army could have done in six months. The British Army attempted

5015-410: The full text of all its articles from 1993 forward. Since its launch, NEJM has added to its site: The George Polk Awards site noted that its 1977 award to The New England Journal of Medicine : "...provided the first significant mainstream visibility for a publication that would achieve enormous attention and prestige in the ensuing decades." The journal usually has the highest impact factor of

5100-558: The highest average rate of philanthropy in the nation, and the city's businesses and institutions rank among the top in the nation for environmental sustainability and new investment. Isaac Johnson , in one of his last official acts as the leader of the Charlestown community before he died on September 30, 1630, named the then-new settlement across the river "Boston". The settlement's name came from Johnson's hometown of Boston, Lincolnshire , from which he, his wife (namesake of

5185-629: The journal's editor, Jeff Drazen , as early as August 2001. That year, both the US Food and Drug Administration and the Journal of the American Medical Association also cast doubt on the validity of the data interpretation that had been published in the NEJM . Merck withdrew the drug from market in September 2004. In December 2005, NEJM published an expression of concern about the original study following discovery that

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5270-564: The journals of internal medicine . According to the Journal Citation Reports , NEJM had a 2017 impact factor of 79.258, ranking it first of 153 journals in the category "General & Internal Medicine". It was the only journal in the category with an impact factor of more than 70. By comparison, the second and third ranked journals in the category ( The Lancet and JAMA ) had impact factors of 53.254 and 47.661 respectively. Theodore Dalrymple feels that this influence

5355-536: The militia, as their stubborn defense made it difficult for the British to capture Charlestown without suffering further irreplaceable casualties. Several weeks later, George Washington took over the militia after the Continental Congress established the Continental Army to unify the revolutionary effort. Both sides faced difficulties and supply shortages in the siege, and the fighting

5440-487: The name think pieces ) by writers not directly affiliated with the publication. However, a newspaper may choose to publish an editorial on the front page. In the English-language press, this occurs rarely and only on topics considered especially important; it is more common, however, in some European countries such as Denmark , Spain , Italy , and France . Many newspapers publish their editorials without

5525-414: The name of the leader writer. Tom Clark, leader-writer for The Guardian , says that it ensures readers discuss the issue at hand rather than the author. On the other hand, an editorial does reflect the position of a newspaper and the head of the newspaper, the editor, is known by name. Whilst the editor will often not write the editorial themselves, they maintain oversight and retain responsibility. In

5610-634: The nation in medical innovation and patient care. Schools such as the Boston Architectural College , Boston College , Boston University , the Harvard Medical School , Tufts University School of Medicine , Northeastern University , Massachusetts College of Art and Design , Wentworth Institute of Technology , Berklee College of Music , the Boston Conservatory , and many others attract students to

5695-572: The nation's busiest ports for both domestic and international trade. Boston's harbor activity was significantly curtailed by the Embargo Act of 1807 (adopted during the Napoleonic Wars ) and the War of 1812 . Foreign trade returned after these hostilities, but Boston's merchants had found alternatives for their capital investments in the meantime. Manufacturing became an important component of

5780-453: The next day and night, giving the enemy time to improve their works, to bring up their cannon, and to put themselves in such a state of defence, that I could promise myself little success in attacking them under all the disadvantages I had to encounter. William Howe, 5th Viscount Howe , in a letter to William Legge, 2nd Earl of Dartmouth , about the British army's decision to leave Boston, dated March 21, 1776. Many crucial events of

5865-419: The official name from the "Town of Boston" to the "City of Boston", and on March 19, 1822, the people of Boston accepted the charter incorporating the city. At the time Boston was chartered as a city, the population was about 46,226, while the area of the city was only 4.8 sq mi (12 km ). In the 1820s, Boston's population grew rapidly, and the city's ethnic composition changed dramatically with

5950-405: The position of the jet stream . Prevailing wind patterns that blow offshore minimize the influence of the Atlantic Ocean. However, in winter, areas near the immediate coast often see more rain than snow, as warm air is sometimes drawn off the Atlantic. The city lies at the border between USDA plant hardiness zones 6b (away from the coastline) and 7a (close to the coastline). The hottest month

6035-413: The settlement on the peninsula had been known as "Shawmut" by William Blaxton and "Tremontaine" by the Puritan settlers he had invited. Prior to European colonization , the region surrounding present-day Boston was inhabited by the Massachusett people who had small, seasonal communities. When a group of settlers led by John Winthrop arrived in 1630, the Shawmut Peninsula was nearly empty of

6120-606: The southwest by the town of Dedham and small portions of Needham and Canton , and to the southeast by the town of Milton , and the city of Quincy . The Charles River separates Boston's Allston-Brighton , Fenway-Kenmore and Back Bay neighborhoods from Watertown and Cambridge, and most of Boston from its own Charlestown neighborhood. The Neponset River forms the boundary between Boston's southern neighborhoods and Quincy and Milton . The Mystic River separates Charlestown from Chelsea and Everett, and Chelsea Creek and Boston Harbor separate East Boston from Downtown ,

6205-509: The temperature dipped down to −10 °F (−23 °C); this was the lowest temperature reading in the city since 1957. In addition, several decades may pass between 100 °F (38 °C) readings; the last such reading occurred on July 24, 2022. The city's average window for freezing temperatures is November 9 through April 5. Official temperature records have ranged from −18 °F (−28 °C) on February 9, 1934, up to 104 °F (40 °C) on July 4, 1911. The record cold daily maximum

6290-539: The third-largest city in the Northeast after New York City and Philadelphia . The larger Greater Boston metropolitan statistical area has a population of 4.9 million as of 2023, making it the largest in New England and the eleventh-largest in the country . Boston was founded on the Shawmut Peninsula in 1630 by Puritan settlers. The city was named after Boston, Lincolnshire , England. During

6375-660: The weekly Image Challenge. Boston Boston is the capital and most populous city in the Commonwealth of Massachusetts in the United States . The city serves as the cultural and financial center of the New England region of the Northeastern United States . It has an area of 48.4 sq mi (125 km ) and a population of 675,647 as of the 2020 census , making it

6460-467: The winter of 2011–12 saw only 9.3 in (23.6 cm) of accumulating snow, but the previous winter, the corresponding figure was 81.0 in (2.06 m). The city's coastal location on the North Atlantic makes the city very prone to nor'easters , which can produce large amounts of snow and rain. Fog is fairly common, particularly in spring and early summer. Due to its coastal location,

6545-736: Was admired for its rarefied literary life and generous artistic patronage . Members of old Boston families—eventually dubbed the Boston Brahmins —came to be regarded as the nation's social and cultural elites. They are often associated with the American upper class , Harvard University , and the Episcopal Church . Boston was a prominent port of the Atlantic slave trade in the New England Colonies , but

6630-549: Was commissioned in 2007, with updates released in 2011, 2014, and 2019. This plan includes the Building Energy Reporting and Disclosure Ordinance, which requires the city's larger buildings to disclose their yearly energy and water use statistics and to partake in an energy assessment every five years. A separate initiative, Resilient Boston Harbor, lays out neighborhood-specific recommendations for coastal resilience . In 2013, Mayor Thomas Menino introduced

6715-433: Was limited to small-scale raids and skirmishes. The narrow Boston Neck, which at that time was only about a hundred feet wide, impeded Washington's ability to invade Boston, and a long stalemate ensued. A young officer, Rufus Putnam , came up with a plan to make portable fortifications out of wood that could be erected on the frozen ground under cover of darkness. Putnam supervised this effort, which successfully installed both

6800-978: Was publicly rebuked for its response to the research issues in editorials appearing in publications including the British Medical Journal and the Journal of the Royal Society of Medicine . NEJM makes articles that meet the criteria for global and public health importance freely available to all readers upon publication at NEJM.org. NEJM also partners with Research4Life in their Access to Research in Health (Hinari) program to grant to low-income countries immediate free access to NEJM.org. NEJM does not charge authors any submission or publication fees. NEJM also works with authors whose articles report research supported by funding bodies with open access mandates, including (but not limited to) Plan S funders and

6885-458: Was published quarterly. In 1823, another publication, the Boston Medical Intelligencer , appeared under the editorship of Jerome V. C. Smith . The editors of the New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science purchased the weekly Intelligencer for $ 600 in 1828, merging the two publications to form the Boston Medical and Surgical Journal , and shifting from quarterly to weekly publication. In 1921,

6970-614: Was reversed in 2013 when it was resold to Boston businessman John W. Henry . In 2016, it was announced General Electric would be moving its corporate headquarters from Connecticut to the Seaport District in Boston, joining many other companies in this rapidly developing neighborhood. The city also saw the completion of the Central Artery/Tunnel Project, known as the Big Dig , in 2007 after many delays and cost overruns. On April 15, 2013, two Chechen Islamist brothers detonated

7055-535: Was soon overtaken by Salem, Massachusetts and Newport, Rhode Island . Boston eventually became a center of the American abolitionist movement . The city reacted largely negatively to the Fugitive Slave Act of 1850 , contributing to President Franklin Pierce 's attempt to make an example of Boston after Anthony Burns 's attempt to escape to freedom. In 1822, the citizens of Boston voted to change

7140-543: Was supported by the mayor and a coalition of business leaders and local philanthropists, but was eventually dropped due to public opposition. The USOC then selected Los Angeles to be the American candidate with Los Angeles ultimately securing the right to host the 2028 Summer Olympics . Nevertheless, Boston is one of eleven U.S. cities which will host matches during the 2026 FIFA World Cup , with games taking place at Gillette Stadium . The geographical center of Boston

7225-447: Was the person most directly responsible for the foundation of Boston by Puritan colonists in 1630. This occurred after Blaxton invited one of their leaders, Isaac Johnson , to cross Back Bay from the failing colony of Charlestown and share the peninsula. The Puritans made the crossing in September 1630. Puritan influence on Boston began even before the settlement was founded with the 1629 Cambridge Agreement . This document created

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