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77-729: The partnership between Nintendo and Universal was announced in May 2015. The construction of a Nintendo-themed area for Universal Studios Japan and both American locations was announced the following year. Construction began on the Universal Studios Japan area in June 2017. Following several delays due to the COVID-19 pandemic , the area opened at Universal Studios Japan on March 18, 2021. The Universal Studios Hollywood location opened on February 17, 2023. Mario creator Shigeru Miyamoto

154-625: A healthy diet are also recommended. Supportive care in severe cases includes treatment to relieve symptoms , fluid therapy , oxygen support and prone positioning , and medications or devices to support other affected vital organs. More severe cases may need treatment in hospital. In those with low oxygen levels, use of the glucocorticoid dexamethasone is recommended to reduce mortality. Noninvasive ventilation and, ultimately, admission to an intensive care unit for mechanical ventilation may be required to support breathing. Extracorporeal membrane oxygenation (ECMO) has been used to address

231-627: A variant of concern (VoC) or a variant of interest (VoI). Many of these variants have shared the more infectious D614G . As of May 2023, the WHO had downgraded all variants of concern to previously circulating as these were no longer detected in new infections. Sub-lineages of the Omicron variant (BA.1 – BA.5) were considered separate VoCs by the WHO until they were downgraded in March 2023 as no longer widely circulating. As of 24 September 2024 ,

308-493: A comprehensive international study. Such deaths include deaths due to healthcare capacity constraints and priorities, as well as reluctance to seek care (to avoid possible infection). Further research may help distinguish the proportions directly caused by COVID-19 from those caused by indirect consequences of the pandemic. In May 2022, the WHO estimated the number of excess deaths by the end of 2021 to be 14.9 million compared to 5.4 million reported COVID-19 deaths, with

385-595: A large number of people". During the COVID-19 pandemic, as with other pandemics, the meaning of this term has been challenged. The end of a pandemic or other epidemic only rarely involves the total disappearance of a disease, and historically, much less attention has been given to defining the ends of epidemics than their beginnings. The ends of particular epidemics have been defined in a variety of ways, differing according to academic field, and differently based on location and social group. An epidemic's end can be considered

462-556: A limited-edition gold colored Power-Up Band was made available to purchase on March 18, 2023. The gold band was also released in Universal Studios Hollywood's area for its first anniversary on February 17, 2024. At Universal Studios Japan, Super Nintendo World is wedged in at the northern end of the park, west of The Wizarding World of Harry Potter and south of the Nintendo headquarters that are just outside of

539-451: A median range of 0.24% to 1.49%. IFRs rise as a function of age (from 0.002% at age 10 and 0.01% at age 25, to 0.4% at age 55, 1.4% at age 65, 4.6% at age 75, and 15% at age 85). These rates vary by a factor of ≈10,000 across the age groups. For comparison, the IFR for middle-aged adults is two orders of magnitude higher than the annualised risk of a fatal automobile accident and much higher than

616-542: A puppet performance of The Tales of Beedle the Bard , and a live performance by Celestina Warbeck and the Banshees. The area also contains many shops and restaurants from the book series including The Leaky Cauldron , Ollivanders Wand Shop , Weasleys' Wizard Wheezes , Borgin and Burkes , Madam Malkin's Robes for All Occasions , Wiseacre's Wizarding Equipment , and Florean Fortescue's Ice Cream Parlour . A third land in

693-824: A random sample have consistently found that total infections considerably exceed the reported case counts. Many countries, early on, had official policies to not test those with only mild symptoms. The strongest risk factors for severe illness are obesity, complications of diabetes , anxiety disorders, and the total number of conditions. During the start of the COVID-19 pandemic it was not clear whether young people were less likely to be infected, or less likely to develop symptoms and be tested. A retrospective cohort study in China found that children and adults were just as likely to be infected. Among more thorough studies, preliminary results from 9 April 2020 found that in Gangelt ,

770-461: A social phenomenon, not just a biological one. Time reported in March 2024 that expert opinions differ on whether or not COVID-19 is considered endemic or pandemic, and that the WHO continued to call the disease a pandemic on its website. During the initial outbreak in Wuhan , the virus and disease were commonly referred to as "coronavirus", "Wuhan coronavirus", "the coronavirus outbreak" and

847-451: A test. Conversely, deaths of people who died from underlying conditions following a positive test may be included. Countries such as Belgium include deaths from suspected cases, including those without a test, thereby increasing counts. Official death counts have been claimed to underreport the actual death toll, because excess mortality (the number of deaths in a period compared to a long-term average) data show an increase in deaths that

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924-414: A third wave of COVID-19 infections in the city. However, guests with a Universal Studios Japan annual pass are allowed to visit the area as of February 4, 2021. It eventually opened to the public on March 18, 2021. A month after opening, the entirety of Universal Studios Japan closed from April 25 to June 7 of 2021, due to COVID-19. On March 10, 2022, Universal Studios Hollywood announced that its version of

1001-539: A tour around a small fraction of the land. On December 26, 2020, the land soft-opened to limited previews for Universal Studios Japan annual passholders. On November 30, 2020, Universal officially announced that the land would open at Universal Studios Japan on February 4, 2021; however, in January the opening was once again delayed indefinitely after the Japanese government reimposed a state of emergency in response to

1078-521: Is a chain of themed areas at Universal Destinations & Experiences based on the Harry Potter media franchise, adapting elements from the Warner Bros.' film series and original novels by J. K. Rowling . The areas were designed by Universal Creative from an exclusive license with Warner Bros. Entertainment . A Harry Potter -themed attraction at either a Disney or Universal park

1155-518: Is associated with COVID-19 and is reported in as many as 88% of cases. The disease is mainly transmitted via the respiratory route when people inhale droplets and small airborne particles (that form an aerosol ) that infected people exhale as they breathe, talk, cough, sneeze, or sing. Infected people are more likely to transmit COVID-19 when they are physically close to other non-infected individuals. However, infection can occur over longer distances, particularly indoors. SARS‑CoV‑2 belongs to

1232-611: Is discouraged altogether by the World Health Organization (WHO), due to limited evidence of its efficacy. The severity of COVID-19 varies. It may take a mild course with few or no symptoms, resembling other common upper respiratory diseases such as the common cold . In 3–4% of cases (7.4% for those over age 65) symptoms are severe enough to cause hospitalisation. Mild cases typically recover within two weeks, while those with severe or critical diseases may take three to six weeks to recover. Among those who have died,

1309-439: Is intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID-19 ). Prior to the COVID-19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated

1386-490: Is not explained by COVID-19 deaths alone. Using such data, estimates of the true number of deaths from COVID-19 worldwide have included a range from 18.2 to 33.5 million (≈27.4 million) by 18 November 2023 by The Economist , as well as over 18.5 million by 1 April 2023 by the Institute for Health Metrics and Evaluation and ≈18.2 million (earlier) deaths between 1 January 2020, and 31 December 2021, by

1463-452: Is the ratio of deaths to diagnoses. This metric can be misleading because of the delay between symptom onset and death and because testing focuses on symptomatic individuals. Based on Johns Hopkins University statistics, the global CFR was 1.02 percent (6,881,955 deaths for 676,609,955 cases) as of 10 March 2023. The number varies by region and has generally declined over time. Several variants have been named by WHO and labelled as

1540-406: Is the seventh known coronavirus to infect people, after 229E , NL63 , OC43 , HKU1 , MERS-CoV , and the original SARS-CoV . The standard method of testing for presence of SARS-CoV-2 is a nucleic acid test , which detects the presence of viral RNA fragments. As these tests detect RNA but not infectious virus, its "ability to determine duration of infectivity of patients is limited." The test

1617-614: Is typically done on respiratory samples obtained by a nasopharyngeal swab ; however, a nasal swab or sputum sample may also be used. The WHO has published several testing protocols for the disease. Preventive measures to reduce the chances of infection include getting vaccinated, staying at home or spending more time outdoors, avoiding crowded places, keeping distance from others, wearing a mask in public, ventilating indoor spaces, managing potential exposure durations, washing hands with soap and water often and for at least twenty seconds, practising good respiratory hygiene, and avoiding touching

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1694-469: The Donkey Kong series was announced to open in 2024, featuring a roller coaster , interactive experiences, and themed merchandise and food. The land was officially revealed on December 5, 2023 with the name of "Donkey Kong Country", as well as new details on the roller coaster "Mine-Cart Madness". On May 2, 2024, it was confirmed that the ride would simulate the sensation of "Jumping The Track" without

1771-797: The Dragon Challenge , opened on June 13, 2019. Other rides include Flight of the Hippogriff , a family roller coaster , and the Hogwarts Express. Other attractions include Ollivanders Wand Shop, the Triwizard Spirit Rally, and the Frog Choir. Hogsmeade contains many gift shops and restaurants from the book series including Dervish and Banges, Honeydukes, Ollivanders, the Three Broomsticks, and

1848-514: The Huanan Seafood Wholesale Market there, but it is possible that human-to-human transmission began earlier. Molecular clock analysis suggests that the first cases were likely to have been between October and November 2019. The scientific consensus is that the virus is most likely of a zoonotic origin, from bats or another closely related mammal. While other explanations such as speculations that SARS-CoV-2

1925-407: The Institute for Health Metrics and Evaluation estimating the true number of cases as of early 2022 to be in the billions. One measure that public health officials and policymakers have used to monitor the pandemic and guide decision-making is the test positivity rate ("percent positive"). According to Johns Hopkins in 2020, one benchmark for a "too high" per cent positive is 5%, which was used by

2002-646: The Magic Kingdom park at Walt Disney World . In January 2007, About.com reported a rumor from a "highly credible source" that the Universal Islands of Adventure park's Lost Continent area was going to be re-themed "to the stories and characters of one of the most popular children's franchises". Other sources followed up in the next few days with unofficial confirmation that the new area would involve Harry Potter . On May 31, 2007, Universal, in partnership with Warner Bros., officially announced

2079-598: The Wizarding World , the Ministry of Magic , will open as part of Universal Epic Universe on May 22, 2025 with attractions based on both the Harry Potter and Fantastic Beasts film series. A theatrical show Le Cirque Arcanus will be included in 1920s wizarding Paris. The land will also feature many shops, restaurants, and experiences as well as a location where guests can time travel by Métro-Floo to

2156-518: The Yoshi's Adventure attraction. Despite the absence of the Yoshi attraction, the extended-queue for Mario Kart: Bowser's Challenge features Yoshi's Adventure -themed corridors. The area also lacked meet-and-greets with Toad until July 15, 2023. On April 3, 2019, Resorts World Sentosa announced that Super Nintendo World, alongside Minion Land would be brought to Universal Studios Singapore , replacing

2233-547: The basic reproduction number (R 0 ) for COVID-19 in January 2020 were between 1.4 and 2.5, but a subsequent analysis claimed that it may be about 5.7 (with a 95 per cent confidence interval of 3.8 to 8.9). In December 2021, the number of cases continued to climb due to several factors, including new COVID-19 variants. As of that 28   December, 282,790,822 individuals worldwide had been confirmed as infected. As of 14 April 2022 , over 500 million cases were confirmed globally. Most cases are unconfirmed, with

2310-474: The variants of interest as specified by the World Health Organization are BA.2.86 and JN.1, and the variants under monitoring are JN.1.7, KP.2, KP.3, KP.3.1.1, JN.1.18, LB.1, and XEC. Symptoms of COVID-19 are variable, ranging from mild symptoms to severe illness. Common symptoms include headache, loss of smell and taste , nasal congestion and runny nose , cough, muscle pain , sore throat , fever, diarrhoea , and breathing difficulties . People with

2387-429: The "Wuhan coronavirus outbreak", with the disease sometimes called "Wuhan pneumonia ". In January 2020, the WHO recommended 2019-nCoV and 2019-nCoV acute respiratory disease as interim names for the virus and disease per 2015 international guidelines against using geographical locations (e.g. Wuhan, China), animal species, or groups of people in disease and virus names in part to prevent social stigma . WHO finalised

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2464-795: The 1990s British Ministry of Magic. The Ministry of Magic will be the home of the land's ride: Harry Potter and the Battle at the Ministry . At the Universal Studios Japan theme park in Osaka , Japan , the Wizarding World of Harry Potter opened on July 15, 2014. It includes the village of Hogsmeade, Harry Potter and the Forbidden Journey ride, and Flight of the Hippogriff roller coaster. Two features in

2541-487: The 2nd floor, immersed in the Mushroom Kingdom with Bowser's Castle across the area. Several Pikmin can be found across the land on ledges, with some carrying objects like coins and a berry. The area includes tower viewer binoculars based on Super Mario 3D Land that utilize AR technology, and include a cameo of Rosalina and her Comet Observatory . Guests can use the separately sold Power-Up Bands and

2618-577: The Donkey Kong Country area in addition to Super Mario Land. COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic ), caused by severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ), began with an outbreak of COVID-19 in Wuhan , China, in December 2019. It spread to other areas of Asia, and then worldwide in early 2020. The World Health Organization (WHO) declared

2695-646: The Hog's Head. At the Universal Studios Florida theme park, another Wizarding World of Harry Potter land opened on July 8, 2014. It includes a re-creation of Diagon Alley and connecting alleys, as well as a small section of Muggle London . It includes the rides Harry Potter and the Escape from Gringotts and the Hogwarts Express . Other attractions include Ollivanders Wand Shop,

2772-514: The Japanese park not found in Orlando or Hollywood are Hogwarts ' Black Lake and live owls. The Wizarding World of Harry Potter opened at Universal Studios Hollywood on April 7, 2016, Replacing The Adventures of Curious George which closed on September 6, 2013. The flagship attraction is the flight-simulating ride Harry Potter and the Forbidden Journey , similar to the Orlando one. Visitors once wore Quidditch-inspired 3D goggles throughout

2849-550: The Lower Lot having severely limited available space, Universal demolished and relocated soundstages to make room for the land's construction. The area's soft-opening in January 2023 revealed what this condensed iteration of the land had to exclude. This location lacks the interactive "Bob-Omb Kaboom Room", "Note Block Rock", and "Slot Machine" sections of the Power-Up Band Key Challenges attraction, and

2926-640: The WHO in the past. As of 10 March 2023, more than 6.88   million deaths had been attributed to COVID-19. The first confirmed death was in Wuhan on 9 January 2020. These numbers vary by region and over time, influenced by testing volume, healthcare system quality, treatment options, government response, time since the initial outbreak, and population characteristics, such as age, sex, and overall health. Multiple measures are used to quantify mortality. Official death counts typically include people who died after testing positive. Such counts exclude deaths without

3003-419: The WHO, US, European Union, and Australia. On 12 November 2022, the WHO released its Global Vaccine Market Report. The report indicated that "inequitable distribution is not unique to COVID-19 vaccines"; countries that are not economically strong struggle to obtain vaccines. On 14 November 2022, the first inhalable vaccine was introduced, developed by Chinese biopharmaceutical company CanSino Biologics , in

3080-539: The Wizarding World of Harry Potter would be added to Islands of Adventure. Both theme parks at the Universal Orlando Resort in Orlando, Florida  – Universal Islands of Adventure and Universal Studios Florida – have Wizarding World of Harry Potter themed environments. Both parks include Hogwarts Express stations allowing passengers to reach both theme parks aboard

3157-501: The area was then unveiled on December 12, 2016. Construction on the land at Universal Studios Japan began in June 2017 with a groundbreaking ceremony, while construction on the land at Universal Studios Hollywood began in early 2019. Following months of leaked information and patents, photographs of Universal Creative 's scale model for the Japan iteration of the area were leaked on July 8, 2019. On January 13, 2020, Universal unveiled

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3234-536: The area. Princess Peach is stationed inside a gazebo -like structure next to her castle, while Mario and Luigi are near the entrance to the Yoshi's Adventure attraction. Toad has no set meet-and-greet spot, with guests being able to visit him in different parts of the lower-level. Since 2022, the area is annually decorated in festive winter-themed decorations as part of the theme park's "No Limit! Christmas Event!". On September 28, 2021, an expansion themed after

3311-448: The broad family of viruses known as coronaviruses . It is a positive-sense single-stranded RNA (+ssRNA) virus, with a single linear RNA segment. Coronaviruses infect humans, other mammals, including livestock and companion animals, and avian species. Human coronaviruses are capable of causing illnesses ranging from the common cold to more severe diseases such as Middle East respiratory syndrome (MERS, fatality rate ≈34%). SARS-CoV-2

3388-648: The centre of a major infection cluster in Germany, 15 per cent of a population sample tested positive for antibodies . Screening for COVID-19 in pregnant women in New York City , and blood donors in the Netherlands, found rates of positive antibody tests that indicated more infections than reported. Seroprevalence -based estimates are conservative as some studies show that persons with mild symptoms do not have detectable antibodies. Initial estimates of

3465-760: The city of Shanghai, China. For the first two years of the pandemic, no specific and effective treatment or cure was available. In 2021, the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) approved the oral antiviral protease inhibitor , Paxlovid (nirmatrelvir plus the HIV antiviral ritonavir ), to treat adult patients. FDA later gave it an EUA. Most cases of COVID-19 are mild. In these, supportive care includes medication such as paracetamol or NSAIDs to relieve symptoms (fever, body aches, cough), adequate intake of oral fluids and rest. Good personal hygiene and

3542-484: The cumulative number of infected individuals (including asymptomatic and undiagnosed infections and excluding vaccinated infected individuals). It is expressed in percentage points. Other studies refer to this metric as the infection fatality risk . In November 2020, a review article in Nature reported estimates of population-weighted IFRs for various countries, excluding deaths in elderly care facilities, and found

3619-605: The dedicated areas of Universal theme parks. The ¥40   billion ($ 351   million U.S.) collaboration built for Universal Studios Japan in Osaka is similar in scale to Universal's investment in the Harry Potter franchise . An interview video that previewed objects being constructed for the land was uploaded on November 29, 2016. Later that day, Universal announced that Super Nintendo World areas would also be built at both American Universal locations in Hollywood and Florida. The first concept image of Japan's iteration of

3696-441: The development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic and severe illness. The COVID-19 vaccines are widely credited for their role in reducing the severity and death caused by COVID-19. As of March 2023, more than 5.5 billion people had received one or more doses (11.8 billion in total) in over 197 countries. The Oxford-AstraZeneca vaccine

3773-513: The eyes, nose, or mouth with unwashed hands. Those diagnosed with COVID-19 or who believe they may be infected are advised by healthcare authorities to stay home except to get medical care, call ahead before visiting a healthcare provider, wear a face mask before entering the healthcare provider's office and when in any room or vehicle with another person, cover coughs and sneezes with a tissue, regularly wash hands with soap and water and avoid sharing personal household items. A COVID-19 vaccine

3850-468: The full-scale replica of the train that appears in the film series . The Wizarding World of Harry Potter opened at Universal Islands of Adventure on June 18, 2010. It includes a re-creation of Hogsmeade and three rides. The flagship attraction is Harry Potter and the Forbidden Journey , which exists within a re-creation of Hogwarts School of Witchcraft and Wizardry . A new roller coaster, Hagrid's Magical Creatures Motorbike Adventure , which replaced

3927-474: The general public beginning in December 2020, made available through government and international programs such as COVAX , aiming to provide vaccine equity . Treatments include novel antiviral drugs and symptom control. Common mitigation measures during the public health emergency included travel restrictions , lockdowns , business restrictions and closures, workplace hazard controls , mask mandates , quarantines, testing systems, and contact tracing of

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4004-665: The infected. The pandemic caused severe social and economic disruption around the world, including the largest global recession since the Great Depression . Widespread supply shortages , including food shortages , were caused by supply chain disruptions and panic buying . Reduced human activity led to an unprecedented temporary decrease in pollution . Educational institutions and public areas were partially or fully closed in many jurisdictions, and many events were cancelled or postponed during 2020 and 2021. Telework became much more common for white-collar workers as

4081-465: The interactive Power-Up Bands and released a music video on YouTube for the upcoming land, using the song " We Are Born to Play " by Galantis & Charli XCX . The land's opening was initially planned for completion before the 2020 Summer Olympics , but was delayed due to the COVID-19 pandemic . On December 18, 2020, a Nintendo Direct about the land went live on Nintendo's official YouTube channel, featuring Mario creator Shigeru Miyamoto hosting

4158-487: The issue of respiratory failure. Existing drugs such as hydroxychloroquine , lopinavir/ritonavir , and ivermectin are not recommended by US or European health authorities, as there is no good evidence they have any useful effect. The antiviral remdesivir is available in the US, Canada, Australia, and several other countries, with varying restrictions; however, it is not recommended for use with mechanical ventilation, and

4235-482: The land would open in 2023 after construction was completed by PCL Construction. with the specific date of February 17 then being announced on December 14, 2022. The area soft-opened under technical rehearsals for reserved-guests on January 12, 2023, and officially opened as planned on February 17, 2023, about a month and a half before the release of Universal / Illumination 's The Super Mario Bros. Movie . To celebrate Super Nintendo World's second anniversary in Japan,

4312-576: The majority of the unreported 9.5 million deaths believed to be direct deaths due the virus, rather than indirect deaths. Some deaths were because people with other conditions could not access medical services . A December 2022 WHO study estimated excess deaths from the pandemic during 2020 and 2021, again concluding ≈14.8 million excess early deaths occurred, reaffirming and detailing their prior calculations from May as well as updating them, addressing criticisms. These numbers do not include measures like years of potential life lost and may make

4389-562: The official Universal Studios smartphone application to keep track of their character stamps, Key Challenges, coins collected, and their high-score on Mario Kart: Koopa's Challenge . Team, individual, and daily scores for the area are viewable within the app as well. The Power-Up Bands also function as Amiibo for their respective characters within Amiibo-compatible Nintendo Switch video games. Several costume character meet-and-greets are located throughout

4466-495: The official names COVID-19 and SARS-CoV-2 on 11 February 2020. Tedros Adhanom Ghebreyesus explained: CO   for corona , VI   for virus , D   for disease and 19 for when the outbreak was first identified (31 December 2019). WHO additionally uses "the COVID-19 virus" and "the virus responsible for COVID-19" in public communications. WHO named variants of concern and variants of interest using Greek letters . The initial practice of naming them according to where

4543-534: The outbreak a public health emergency of international concern (PHEIC) on 30 January 2020, and assessed the outbreak as having become a pandemic on 11 March. COVID-19 symptoms range from asymptomatic to deadly, but most commonly include fever, sore throat , nocturnal cough , and fatigue. Transmission of the virus is often through airborne particles . Mutations have produced many strains (variants) with varying degrees of infectivity and virulence . COVID-19 vaccines were developed rapidly and deployed to

4620-407: The pandemic 2021's leading cause of death . The time between symptom onset and death ranges from   6 to 41 days, typically about 14 days. Mortality rates increase as a function of age. People at the greatest mortality risk are the elderly and those with underlying conditions. The infection fatality ratio (IFR) is the cumulative number of deaths attributed to the disease divided by

4697-495: The pandemic evolved. Misinformation circulated through social media and mass media , and political tensions intensified . The pandemic raised issues of racial and geographic discrimination , health equity , and the balance between public health imperatives and individual rights . The WHO ended the PHEIC for COVID-19 on 5 May 2023. The disease has continued to circulate, but as of 2024, experts were uncertain as to whether it

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4774-441: The park's Madagascar area. This version is currently expected to open in 2025. As of 2024, no attractions have been confirmed for this iteration. On January 24, 2020, Universal confirmed that a Super Nintendo World themed area would be included in the upcoming Universal Epic Universe park at Universal Orlando Resort . Several Comcast executives reaffirmed it one week later. The park was originally scheduled to open in 2023, but

4851-479: The planned opening has been delayed to 2025 as a result of the COVID-19 pandemic. Epic Universe's iteration of the land was officially announced in February 2023, with Universal Destinations & Experiences CEO Mark Woodbury calling it the "worst-kept secret in history". On May 2, 2024, the official Nintendo and Universal channels announced that Super Nintendo World at Universal Epic Universe will arrive in 2025 with

4928-478: The population's age structure and the age-specific pattern of infections. There have also been reviews that have compared the fatality rate of this pandemic with prior pandemics, such as MERS-CoV. For comparison the infection mortality rate of seasonal flu in the United States is 0.1%, which is 13 times lower than COVID-19. Another metric in assessing death rate is the case fatality ratio (CFR), which

5005-459: The property. Guests enter the area through a Warp Pipe from an entrance plaza. The entrance plaza can be accessed from a walkway that branches right next to the WaterWorld sign. The entrance plaza has lamp posts, a power star in the pavement, and Super Nintendo World signage next to the pipe. The pipe leads into Princess Peach's Castle . When guests exit the castle, they enter the courtyard on

5082-462: The risk of dying from seasonal influenza . In December 2020, a systematic review and meta-analysis estimated that population-weighted IFR was 0.5% to 1% in some countries (France, Netherlands, New Zealand, and Portugal), 1% to 2% in other countries (Australia, England, Lithuania, and Spain), and about 2.5% in Italy. This study reported that most of the differences reflected corresponding differences in

5159-496: The same infection may have different symptoms, and their symptoms may change over time. Three common clusters of symptoms have been identified: one respiratory symptom cluster with cough, sputum , shortness of breath, and fever; a musculoskeletal symptom cluster with muscle and joint pain, headache, and fatigue; a cluster of digestive symptoms with abdominal pain, vomiting, and diarrhoea. In people without prior ear, nose, and throat disorders, loss of taste combined with loss of smell

5236-494: The spread of the virus within the community, and mitigation strategies (commonly known as " flattening the curve ") that attempt to lessen the effects of the virus on society, but which still tolerate some level of transmission within the community. These initial strategies can be pursued sequentially or simultaneously during the acquired immunity phase through natural and vaccine-induced immunity . The Wizarding World of Harry Potter The Wizarding World of Harry Potter

5313-411: The time from symptom onset to death has ranged from two to eight weeks. Prolonged prothrombin time and elevated C-reactive protein levels on admission to the hospital are associated with severe course of COVID-19 and with a transfer to intensive care units (ICU). Between 5% and 50% of COVID-19 patients experience long COVID , a condition characterised by long-term consequences persisting after

5390-694: The typical convalescence period of the disease. The most commonly reported clinical presentations are fatigue and memory problems, as well as malaise , headaches, shortness of breath , loss of smell, muscle weakness , low fever and cognitive dysfunction . Many countries attempted to slow or stop the spread of COVID-19 by recommending, mandating or prohibiting behaviour changes, while others relied primarily on providing information. Measures ranged from public advisories to stringent lockdowns. Outbreak control strategies are divided into elimination and mitigation. Experts differentiate between elimination strategies (known as " zero-COVID ") that aim to completely stop

5467-555: The use of screens. On November 11, 2024, Universal Studios Japan announced that the Japan version of Donkey Kong Country would open on December 11, 2024, and it was revealed that the Mushroom Kingdom section is named Super Mario Land . Universal Studios Hollywood's smaller Super Nintendo World area is located in the park's Lower Lot , wedged between the Jurassic World area and Transformers: The Ride – 3D . Due to

5544-543: The variants were identified (e.g. Delta began as the " Indian variant") is no longer common. A more systematic naming scheme reflects the variant's PANGO lineage (e.g., Omicron 's lineage is B.1.1.529) and is used for other variants. SARS-CoV-2 is a virus closely related to bat coronaviruses , pangolin coronaviruses, and SARS-CoV . The first known outbreak (the 2019–2020 COVID-19 outbreak in mainland China ) started in Wuhan , Hubei, China, in December 2019. Many early cases were linked to people who had visited

5621-443: Was accidentally released from a laboratory have been proposed, as of 2021 these were not supported by evidence. Official "case" counts refer to the number of people who have been tested for COVID-19 and whose test has been confirmed positive according to official protocols whether or not they experienced symptomatic disease. Due to the effect of sampling bias , studies which obtain a more accurate number by extrapolating from

5698-440: Was heavily involved in the design of the area and attractions. Following several years of declining gaming revenue and console market share, Nintendo sought avenues to leverage and develop its intellectual properties, entering into a theme park partnership with Universal Destinations & Experiences . The partnership, announced in May 2015 and detailed the next year, would use Mario and other Nintendo franchises as themes in

5775-422: Was rumored in 2003. However, the rights to the Harry Potter franchise had been acquired by Warner Bros. , who denied all rumors. Both Disney and Universal entered bidding negotiations with Warner Bros. and Rowling for the theme park rights to Harry Potter . In 2004, Rowling signed a letter-of-intent with Disney, with the company intending to develop a Harry Potter section within an area of Fantasyland at

5852-457: Was still a pandemic. Pandemics and their ends are not well-defined, and whether or not one has ended differs according to the definition used. As of 24 November 2024, COVID-19 has caused 7,075,455 confirmed deaths. The COVID-19 pandemic ranks as the fifth- deadliest pandemic or epidemic in history . In epidemiology , a pandemic is defined as "an epidemic occurring over a very wide area, crossing international boundaries, and usually affecting

5929-509: Was the most widely used. According to a June 2022 study, COVID-19 vaccines prevented an additional 14.4 million to 19.8 million deaths in 185 countries and territories from 8 December 2020 to 8 December 2021. On 8 November 2022, the first recombinant protein-based COVID-19 vaccine (Novavax's booster Nuvaxovid ) was authorised for use in adults in the United Kingdom. It has subsequently received endorsement/authorisation from

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