66-477: The Peterbald is a hairless cat breed of Russian origin. It was created in St. Petersburg in 1994 from an experimental cross of a Don Sphynx and an Oriental Shorthair . They have an Oriental build with a dominant hair-losing gene. The breed was accepted for Championship status in 2009. The Peterbald breed was born during the latter half of 1994 in St. Petersburg , Russia, the result of an experimental mating of
132-418: A Don Sphynx (also known as Don Hairless, Donskoy or Donsky) male named Afinogen Myth and an Oriental Shorthair female World Champion named Radma von Jagerhov, by Russian felinologist Olga S. Mironova . The first two litters produced four Peterbald kittens: Mandarin iz Murino, Muscat iz Murino, Nezhenka iz Murino and Nocturne iz Murino. These four Peterbalds were the foundation stock of the breed. In 1996,
198-412: A postmortem examination or an obduction , is a medical procedure that consists of a thorough examination of a human corpse to determine the cause and manner of a person's death and to evaluate any disease or injury that may be present. It is usually performed by a specialized medical doctor called a pathologist . Autopsies are either performed for legal or medical purposes. A forensic autopsy
264-558: A coma. In the case of sleep, electroencephalograms (EEGs) are used to tell the difference. The category of "brain death" is seen as problematic by some scholars. For instance, Dr. Franklin Miller, a senior faculty member at the Department of Bioethics, National Institutes of Health, notes: "By the late 1990s... the equation of brain death with death of the human being was increasingly challenged by scholars, based on evidence regarding
330-409: A concept of an afterlife that may hold the idea of judgment of good and bad deeds in one's life. There are also different customs for honoring the body, such as a funeral , cremation , or sky burial . After a death, an obituary may be posted in a newspaper, and the "survived by" kin and friends usually go through the grieving process . The concept of death is the key to human understanding of
396-446: A definition of the moment of death is required, doctors and coroners usually turn to "brain death" or "biological death" to define a person as being dead; people are considered dead when the electrical activity in their brain ceases. It is presumed that an end of electrical activity indicates the end of consciousness . Suspension of consciousness must be permanent and not transient, as occurs during certain sleep stages, and especially
462-435: A living organism . The remains of a former organism normally begin to decompose shortly after death. Death eventually and inevitably occurs in all organisms. Some organisms, such as Turritopsis dohrnii , are biologically immortal ; however, they can still die from means other than aging . Death is generally applied to whole organisms; the equivalent for individual components of an organism, such as cells or tissues ,
528-425: A living being can survive all calamities but eventually dies due to causes relating to old age. Conversely, premature death can refer to a death that occurs before old age arrives, for example, human death before a person reaches the age of 75. Animal and plant cells normally reproduce and function during the whole period of natural existence, but the aging process derives from the deterioration of cellular activity and
594-488: A person has definitively died has proven difficult. Initially, death was defined as occurring when breathing and the heartbeat ceased, a status still known as clinical death . However, the development of cardiopulmonary resuscitation (CPR) meant that such a state was no longer strictly irreversible. Brain death was then considered a more fitting option, but several definitions exist for this. Some people believe that all brain functions must cease. Others believe that even if
660-401: A previous miscarriage, and the use of abortion can increase the chances of having a miscarriage. An abortion may be performed for many reasons, such as pregnancy from rape , financial constraints of having a child, teenage pregnancy , and the lack of support from a significant other . There are two forms of abortion: a medical abortion and an in-clinic abortion or sometimes referred to as
726-402: A surgical abortion. A medical abortion involves taking a pill that will terminate the pregnancy no more than 11 weeks past the last period , and an in-clinic abortion involves a medical procedure using suction to empty the uterus; this is possible after 12 weeks, but it may be more difficult to find an operating doctor who will go through with the procedure. Senescence refers to a scenario when
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#1732781052560792-441: A vegetative state or coma, in that the former situation describes a state that is beyond recovery. EEGs can detect spurious electrical impulses, while certain drugs, hypoglycemia , hypoxia , or hypothermia can suppress or even stop brain activity temporarily; because of this, hospitals have protocols for determining brain death involving EEGs at widely separated intervals under defined conditions. People maintaining that only
858-637: Is necrosis . Something that is not considered an organism, such as a virus , can be physically destroyed but is not said to die , as a virus is not considered alive in the first place. As of the early 21st century, 56 million people die per year. The most common reason is aging , followed by cardiovascular disease , which is a disease that affects the heart or blood vessels . As of 2022, an estimated total of almost 110 billion humans have died, or roughly 94% of all humans to have ever lived. A substudy of gerontology known as biogerontology seeks to eliminate death by natural aging in humans, often through
924-408: Is a finite supply presented at birth. Later, Goldstone proposed the concept of production or income of adaptation energy which may be stored (up to a limit) as a capital reserve of adaptation. In recent works, adaptation energy is considered an internal coordinate on the "dominant path" in the model of adaptation. It is demonstrated that oscillations of well-being appear when the reserve of adaptability
990-427: Is almost exhausted. In 2012, suicide overtook car crashes as the leading cause of human injury deaths in the U.S., followed by poisoning, falls, and murder. Accidents and disasters, from nuclear disasters to structural collapses , also claim lives. One of the deadliest incidents of all time is the 1975 Banqiao Dam Failure , with varying estimates, up to 240,000 dead. Other incidents with high death tolls are
1056-494: Is an irreversible process where someone loses their existence as a person. Historically, attempts to define the exact moment of a human's death have been subjective or imprecise. Death was defined as the cessation of heartbeat (cardiac arrest) and breathing , but the development of CPR and prompt defibrillation have rendered that definition inadequate because breathing and heartbeat can sometimes be restarted. This type of death where circulatory and respiratory arrest happens
1122-501: Is carried out when the cause of death may be a criminal matter, while a clinical or academic autopsy is performed to find the medical cause of death and is used in cases of unknown or uncertain death, or for research purposes. Autopsies can be further classified into cases where external examination suffices, and those where the body is dissected and an internal examination is conducted. Permission from next of kin may be required for internal autopsy in some cases. Once an internal autopsy
1188-438: Is complete the body is generally reconstituted by sewing it back together. A necropsy, which is not always a medical procedure, was a term previously used to describe an unregulated postmortem examination. In modern times, this term is more commonly associated with the corpses of animals. Death before birth can happen in several ways: stillbirth , when the fetus dies before or during the delivery process; miscarriage , when
1254-883: Is determined by the rate of aging for a species inherent in its genes . A recognized method of extending maximum lifespan is calorie restriction . Theoretically, the extension of the maximum lifespan can be achieved by reducing the rate of aging damage, by periodic replacement of damaged tissues , molecular repair , or rejuvenation of deteriorated cells and tissues. A United States poll found religious and irreligious people, as well as men and women and people of different economic classes, have similar rates of support for life extension, while Africans and Hispanics have higher rates of support than white people. 38% said they would desire to have their aging process cured. Researchers of life extension can be known as "biomedical gerontologists ." They try to understand aging, and develop treatments to reverse aging processes, or at least slow them for
1320-714: Is illegal in the Netherlands to breed with parent cats which bear genetic mutations or other physical abnormalities that cause health or welfare issues in their offspring. The lack of protective fur in hairless cats, such as the Peterbald, is one of these banned mutations in parent cats. List of cat body-type mutations#Hairlessness Cats , like all living organisms, occasionally have mutations that affect their body type. Sometimes, these mutations are striking enough that humans select for and perpetuate them. However, in relatively small or isolated feral cat populations
1386-481: Is known as the circulatory definition of death (CDD). Proponents of the CDD believe this definition is reasonable because a person with permanent loss of circulatory and respiratory function should be considered dead. Critics of this definition state that while cessation of these functions may be permanent, it does not mean the situation is irreversible because if CPR is applied fast enough, the person could be revived. Thus,
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#17327810525601452-406: Is more of a process than a single event. It implies a slow shift from one spiritual state to another. Other definitions for death focus on the character of cessation of organismic functioning and human death, which refers to irreversible loss of personhood. More specifically, death occurs when a living entity experiences irreversible cessation of all functioning. As it pertains to human life, death
1518-669: Is now seen as a process, more than an event: conditions once considered indicative of death are now reversible. Where in the process, a dividing line is drawn between life and death depends on factors beyond the presence or absence of vital signs . In general, clinical death is neither necessary nor sufficient for a determination of legal death . A patient with working heart and lungs determined to be brain dead can be pronounced legally dead without clinical death occurring. Life extension refers to an increase in maximum or average lifespan , especially in humans, by slowing or reversing aging processes through anti-aging measures. Aging
1584-501: Is something humans share with cetaceans called the mammalian diving reflex . As medical technologies advance, ideas about when death occurs may have to be reevaluated in light of the ability to restore a person to vitality after longer periods of apparent death (as happened when CPR and defibrillation showed that cessation of heartbeat is inadequate as a decisive indicator of death). The lack of electrical brain activity may not be enough to consider someone scientifically dead. Therefore,
1650-483: Is the most common cause of death worldwide. Aging is seen as inevitable, so according to Aubrey de Grey little is spent on research into anti-aging therapies, a phenomenon known as pro-aging trance . The average lifespan is determined by vulnerability to accidents and age or lifestyle-related afflictions such as cancer or cardiovascular disease . Extension of lifespan can be achieved by good diet , exercise, and avoidance of hazards such as smoking . Maximum lifespan
1716-438: Is to say a long muzzle, large set-apart ears, flat cheekbones, and an elegant body on long legs. Therefore, all standards for this breed encourage mating with Oriental and Siamese cats and semi-longhair variations of those (such as Balinese and Javanese ). The Balinese and Javanese were eliminated from the acceptable outcross list in 2005. The Peterbald was accepted for Championship class competition, effective May 1, 2009, in
1782-463: Is viewed as problematic by some scholars, there are proponents of it that believe this definition of death is the most reasonable for distinguishing life from death. The reasoning behind the support for this definition is that brain death has a set of criteria that is reliable and reproducible. Also, the brain is crucial in determining our identity or who we are as human beings. The distinction should be made that "brain death" cannot be equated with one in
1848-586: The 1931 China floods , which killed an estimated 4 million people, although estimates widely vary; the 1887 Yellow River flood , which killed an estimated 2 million people in China; and the 1970 Bhola cyclone , which killed as many as 500,000 people in Pakistan. If naturally occurring famines are considered natural disasters, the Chinese famine of 1906–1907 , which killed 15–20 million people, can be considered
1914-688: The American Cat Fanciers Association (ACFA) in August 2008. Effective May 2008, TICA recognises the "brush coat" Peterbald for Championship competition. Peterbalds resemble Oriental Shorthairs in body-type. They have a dominant hair-losing gene inherited from the Don Sphynx, and can be born bald, flocked, velour, brush, or with a straight coat. Those born with hair, excepting the straight-coats, can lose their hair over time. They come in all colours and markings. Members of
1980-525: The Wanggongchang explosion (when a gunpowder factory ended up with 20,000 deaths), a collapse of a wall of Circus Maximus that killed 13,000 people, and the Chernobyl disaster that killed between 95 and 4,000 people. Natural disasters kill around 45,000 people annually, although this number can vary to millions to thousands on a per-decade basis. Some of the deadliest natural disasters are
2046-458: The brainstem is still alive, the personality and identity are irretrievably lost, so therefore, the person should be considered entirely dead. Brain death is sometimes used as a legal definition of death. For all organisms with a brain, death can instead be focused on this organ. The cause of death is usually considered important and an autopsy can be done. There are many causes, from accidents to diseases. Many cultures and religions have
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2112-485: The embryo dies before independent survival; and abortion , the artificial termination of the pregnancy. Stillbirth and miscarriage can happen for various reasons, while abortion is carried out purposely. Stillbirth can happen right before or after the delivery of a fetus. It can result from defects of the fetus or risk factors present in the mother. Reductions of these factors, caesarean sections when risks are present, and early detection of birth defects have lowered
2178-454: The neo-cortex of the brain is necessary for consciousness sometimes argue that only electrical activity should be considered when defining death. Eventually, the criterion for death may be the permanent and irreversible loss of cognitive function, as evidenced by the death of the cerebral cortex . All hope of recovering human thought and personality is then gone, given current and foreseeable medical technology. Even by whole-brain criteria,
2244-453: The 20th century and could kill 1 billion people worldwide in the 21st century, a World Health Organization report warned. Many leading developed world causes of death can be postponed by diet and physical activity , but the accelerating incidence of disease with age still imposes limits on human longevity . The evolutionary cause of aging is, at best, only beginning to be understood. It has been suggested that direct intervention in
2310-702: The President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research in 1980. They concluded that this approach to defining death sufficed in reaching a uniform definition nationwide. A multitude of reasons was presented to support this definition, including uniformity of standards in law for establishing death, consumption of a family's fiscal resources for artificial life support, and legal establishment for equating brain death with death to proceed with organ donation . Aside from
2376-550: The United Nations Special Reporter on the Right to Food, 2000 – Mar 2008, mortality due to malnutrition accounted for 58% of the total mortality rate in 2006. Ziegler says worldwide, approximately 62 million people died from all causes and of those deaths, more than 36 million died of hunger or diseases due to deficiencies in micronutrients . Tobacco smoking killed 100 million people worldwide in
2442-404: The aging process may now be the most effective intervention against major causes of death. Selye proposed a unified non-specific approach to many causes of death. He demonstrated that stress decreases the adaptability of an organism and proposed to describe adaptability as a special resource, adaptation energy . The animal dies when this resource is exhausted. Selye assumed that adaptability
2508-434: The anatomical, physiological and behavioural characteristics which are likely to put at risk the health and welfare of either the offspring or the female parent. Since 2014, it is illegal in the Netherlands to breed with parent cats which bear genetic mutations or other physical abnormalities that cause health or welfare issues in their offspring. Examples of these genetic mutations and physical abnormalities are dwarfism ,
2574-424: The animal’s welfare it is illegal in several countries or states to breed with parent cats that bear certain of these hypertype mutations. This article gives a selection of cat body type mutant alleles and the associated mutations with a brief description. A germ-cell mutation occurred in a male Persian cat called Treker in 1995, resulting in diminutive, but healthy and normally-proportioned, offspring. Treker and
2640-414: The application of natural processes found in certain organisms. However, as humans do not have the means to apply this to themselves, they have to use other ways to reach the maximum lifespan for a human, often through lifestyle changes, such as calorie reduction , dieting , and exercise . The idea of lifespan extension is considered and studied as a way for people to live longer. Determining when
2706-444: The arguments for and against the CDD boil down to defining the actual words "permanent" and "irreversible," which further complicates the challenge of defining death. Furthermore, events causally linked to death in the past no longer kill in all circumstances; without a functioning heart or lungs, life can sometimes be sustained with a combination of life support devices, organ transplants , and artificial pacemakers . Today, where
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2772-439: The array of biological functioning displayed by patients correctly diagnosed as having this condition who were maintained on mechanical ventilation for substantial periods of time. These patients maintained the ability to sustain circulation and respiration, control temperature, excrete wastes, heal wounds, fight infections and, most dramatically, to gestate fetuses (in the case of pregnant "brain-dead" women)." While "brain death"
2838-501: The brain must have completely ceased. However, in other jurisdictions, some follow the brainstem version of brain death. Afterward, a death certificate is issued in most jurisdictions, either by a doctor or by an administrative office, upon presentation of a doctor's declaration of death. There are many anecdotal references to people being declared dead by physicians and then "coming back to life," sometimes days later in their coffin or when embalming procedures are about to begin. From
2904-559: The breed have a slim and muscular build. They have a narrow and long head with a straight profile, almond-shaped eyes, wedge-shaped muzzle, and large, set-apart ears. They have a long whip-like tail, webbed feet and oval paws that allow them to grasp objects and open levered doorknobs. Peterbalds are sweet-tempered, affectionate, peaceful, curious, smart, and energetic. They are medium vocal and tend to follow their owners and want to be with them. Peterbalds typically live in harmony with other cats and pets, and also with children. Since 2014, it
2970-696: The breed was adopted in the Russian Selectional Feline Federation (SFF) and given a standard and an abbreviation (PBD). In 1997 it was adopted in The International Cat Association (TICA) with the abbreviation PD, and in 2003 in the World Cat Federation (WCF) with the abbreviation PBD. Other used handles of the breed are PTB, PD and PSX. These days the breed develops in the direction of modern Oriental and Siamese body-types, that
3036-471: The concept of information-theoretic death has been suggested as a better means of defining when true death occurs, though the concept has few practical applications outside the field of cryonics . The leading cause of human death in developing countries is infectious disease . The leading causes in developed countries are atherosclerosis ( heart disease and stroke), cancer, and other diseases related to obesity and aging . By an extremely wide margin,
3102-550: The deadliest natural disaster in recorded history. In animals, predation can be a common cause of death. Livestock have a 6% death rate from predation. However, younger animals are more susceptible to predation. For example, 50% of young foxes die to birds , bobcats , coyotes , and other foxes as well. Young bear cubs in the Yellowstone National Park only have a 40% chance to survive to adulthood from other bears and predators. An autopsy, also known as
3168-556: The determination of brain death can be complicated. At present, in most places, the more conservative definition of death (irreversible cessation of electrical activity in the whole brain, as opposed to just in the neo-cortex) has been adopted. One example is the Uniform Determination Of Death Act in the United States. In the past, the adoption of this whole-brain definition was a conclusion of
3234-558: The females with which he was mated were normally sized, but 75% of the kittens sired by Treker inherited diminutive stature, but of normal proportions. The gene was found to be dominant and the diminutive offspring were sold as teacup or toy Persians. Toy and Teacup Persians are a separate breed and not all cats advertised under those names result from Treker's dominant mutation. Most teacup and toy size Persian kittens raised now are descendants from Silver and Golden color division to reduce cat size and are in no way related to Treker. Many of
3300-439: The figure to be closer to 800. In cases of electric shock , cardiopulmonary resuscitation (CPR) for an hour or longer can allow stunned nerves to recover, allowing an apparently dead person to survive. People found unconscious under icy water may survive if their faces are kept continuously cold until they arrive at an emergency room . This "diving response," in which metabolic activity and oxygen requirements are minimal,
3366-434: The flaws in this approach is that there are many organisms that are alive but probably not conscious. Another problem is in defining consciousness, which has many different definitions given by modern scientists, psychologists and philosophers. Additionally, many religious traditions, including Abrahamic and Dharmic traditions, hold that death does not (or may not) entail the end of consciousness. In certain cultures, death
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#17327810525603432-483: The issue of support of or dispute against brain death, there is another inherent problem in this categorical definition: the variability of its application in medical practice. In 1995, the American Academy of Neurology (AAN) established the criteria that became the medical standard for diagnosing neurologic death. At that time, three clinical features had to be satisfied to determine "irreversible cessation" of
3498-551: The jellyfish Turritopsis dohrnii , the hydra , and the planarian . Unnatural causes of death include suicide and predation . Of all causes, roughly 150,000 people die around the world each day. Of these, two-thirds die directly or indirectly due to senescence, but in industrialized countries – such as the United States, the United Kingdom, and Germany – the rate approaches 90% (i.e., nearly nine out of ten of all deaths are related to senescence). Physiological death
3564-523: The lack of protecting fur in hairless cats, and fold-eared cats. Furthermore, several countries or states have prohibited breeding with certain of the genetic mutations in cats, including Scotland , Victoria and the Australian Capital Territory ( Australia ), Austria , and Flanders ( Belgium ). Death Death is the end of life ; the irreversible cessation of all biological functions that sustain
3630-476: The largest unifying cause of death in the developed world is biological aging, leading to various complications known as aging-associated diseases . These conditions cause loss of homeostasis , leading to cardiac arrest, causing loss of oxygen and nutrient supply, causing irreversible deterioration of the brain and other tissues . Of the roughly 150,000 people who die each day across the globe, about two thirds die of age-related causes. In industrialized nations,
3696-626: The major cat registries do not allow the registry and breeding of cat breeds which bear certain of these genetic mutations, nor recognise them, due to concerns about the animal’s welfare. Breeding with parent animals that bear hypertype mutations is effectively banned in Europe under the European Convention for the Protection of Pet Animals : Any person who selects a pet animal for breeding shall be responsible for having regard to
3762-583: The mid-18th century onwards, there was an upsurge in the public's fear of being mistakenly buried alive and much debate about the uncertainty of the signs of death. Various suggestions were made to test for signs of life before burial, ranging from pouring vinegar and pepper into the corpse's mouth to applying red hot pokers to the feet or into the rectum . Writing in 1895, the physician J.C. Ouseley claimed that as many as 2,700 people were buried prematurely each year in England and Wales, although some estimates peg
3828-466: The moment when life ends. Determining when death has occurred is difficult, as cessation of life functions is often not simultaneous across organ systems. Such determination, therefore, requires drawing precise conceptual boundaries between life and death. This is difficult due to there being little consensus on how to define life. It is possible to define life in terms of consciousness. When consciousness ceases, an organism can be said to have died. One of
3894-497: The mutations can also spread without human intervention, for example on islands. Cat breeders exploit the naturally occurring mutations by selectively breeding them in a small gene pool, resulting in the creation of new cat breeds with unusual physical characteristics. The term designer cat is often used to refer to these cat breeds. This is not always in the best interests of the cat, as many of these mutations are harmful; some are even lethal in their homozygous form. To protect
3960-447: The other hand, believe that the rule does not uphold the best interests of the donors and that the rule does not effectively promote organ donation. Signs of death or strong indications that a warm-blooded animal is no longer alive are: The stages that follow after death are: The death of a person has legal consequences that may vary between jurisdictions. Most countries follow the whole-brain death criteria, where all functions of
4026-420: The phenomenon. There are many scientific approaches and various interpretations of the concept. Additionally, the advent of life-sustaining therapy and the numerous criteria for defining death from both a medical and legal standpoint have made it difficult to create a single unifying definition. One of the challenges in defining death is in distinguishing it from life. As a point in time, death seems to refer to
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#17327810525604092-628: The proportion is much higher, approaching 90%. With improved medical capability, dying has become a condition to be managed . In developing nations , inferior sanitary conditions and lack of access to modern medical technology make death from infectious diseases more common than in developed countries . One such disease is tuberculosis , a bacterial disease that killed 1.8 million people in 2015. In 2004, malaria caused about 2.7 million deaths annually. The AIDS death toll in Africa may reach 90–100 million by 2025. According to Jean Ziegler ,
4158-673: The rate of stillbirth. However, 1% of births in the United States end in a stillbirth. A miscarriage is defined by the World Health Organization as, "The expulsion or extraction from its mother of an embryo or fetus weighing 500g or less." Miscarriage is one of the most frequent problems in pregnancy, and is reported in around 12–15% of all clinical pregnancies ; however, by including pregnancy losses during menstruation , it could be up to 17–22% of all pregnancies. There are many risk-factors involved in miscarriage; consumption of caffeine , tobacco , alcohol , drugs, having
4224-722: The ruination of regular functioning. The aptitude of cells for gradual deterioration and mortality means that cells are naturally sentenced to stable and long-term loss of living capacities, even despite continuing metabolic reactions and viability. In the United Kingdom, for example, nine out of ten of all the deaths that occur daily relates to senescence, while around the world, it accounts for two-thirds of 150,000 deaths that take place daily. Almost all animals who survive external hazards to their biological functioning eventually die from biological aging , known in life sciences as "senescence." Some organisms experience negligible senescence , even exhibiting biological immortality . These include
4290-433: The rule: there must be an official declaration of death in a person before starting organ procurement, or that organ procurement cannot result in the death of the donor. A great deal of controversy has surrounded the definition of death and the dead donor rule. Advocates of the rule believe that the rule is legitimate in protecting organ donors while also countering any moral or legal objection to organ procurement. Critics, on
4356-414: The total brain, including coma with clear etiology, cessation of breathing, and lack of brainstem reflexes. These criteria were updated again, most recently in 2010, but substantial discrepancies remain across hospitals and medical specialties. The problem of defining death is especially imperative as it pertains to the dead donor rule , which could be understood as one of the following interpretations of
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