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The Duke Energy Convention Center is a convention center located in downtown Cincinnati, Ohio , United States , covering two city blocks bounded by Elm Street, 5th Street, 6th Street, and Central Avenue.

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69-666: The convention center opened in 1967 as the Convention-Exposition Center . It was renamed the Albert B. Sabin Convention and Exposition Center on November 14, 1985, amid national criticism that Second Street had been named after Pete Rose instead of the pioneering medical researcher. The convention was renovated and expanded in 2006. In 2020, the center was designed for use as a field hospital along with other similar facilities nationwide to house patients during

138-636: A center of pork processing in the region. From 1810 to 1830, the city's population nearly tripled, from 9,642 to 24,831. Construction on the Miami and Erie Canal began on July 21, 1825, when it was called the Miami Canal, related to its origin at the Great Miami River . The first section of the canal was opened for business in 1827. In 1827, the canal connected Cincinnati to nearby Middletown ; by 1840, it had reached Toledo . Railroads were

207-474: A century and a half, Cincinnati went unchallenged as the most prominent of Ohio's cities, a role that earned it the nickname of "chief city of Ohio" in the 1879 New American Cyclopædia . In addition to this book, countless other books have documented the social history of both the city and its frontier people. The city fathers, of Anglo-American families of prominence, were Episcopalian . Inspired by its earlier horseback circuit preachers , early Methodism

276-424: A crescent around the city: Mount Adams , Walnut Hills , Mount Auburn , Vine Street Hill , College Hill , Fairmont (now rendered Fairmount ), and Mount Harrison (now known as Price Hill ). The name refers to ancient Rome, reputed to be built on seven hills. "Queen City" is taken from an 1819 newspaper article and further immortalized by the 1854 poem "Catawba Wine". In it, Henry Wadsworth Longfellow wrote of

345-591: A keystone of civic history; and among Methodist institutions were The Christ Hospital as well as projects of the German Methodist Church . One of Cincinnati's biggest proponents of Methodism was the Irish immigrant James Gamble , who together with William Procter founded Procter & Gamble ; in addition to being a devout Methodist, Gamble and his estate donated money to construct Methodist churches throughout Greater Cincinnati. Cincinnati, being

414-510: A male householder with no wife present, and 53.3% were non-families. 43.4% of all households were made up of individuals, and 9.9% had someone living alone who was 65 years of age or older. The average household size was 2.09 and the average family size was 3.00. The median age in the city was 32.5 years. 21.6% of residents were under the age of 18; 14.6% were between the ages of 18 and 24; 28.4% were from 25 to 44; 24.1% were from 45 to 64; and 10.8% were 65 years of age or older. The gender makeup of

483-662: A minor league ice hockey team. The city's largest institution of higher education, the University of Cincinnati , was founded in 1819 as a municipal college and is now ranked as one of the 50 largest in the United States. The Sixth Circuit Court of Appeals is based in the city. Two years after the founding of the settlement then known as "Losantiville", Arthur St. Clair , the governor of the Northwest Territory , changed its name to "Cincinnati", possibly at

552-704: A number of hills, bluffs, and low ridges overlooking the Ohio in the Bluegrass region of the country. The tristate is geographically located within the Midwest at the far northern extremity of the Upland South . Three municipalities are enveloped by the city: Norwood , Elmwood Place , and Saint Bernard . Norwood is a business and industrial city, while Elmwood Place and Saint Bernard are small, primarily residential, villages. Cincinnati does not have an exclave, but

621-705: A popular stop on the Underground Railroad . In 2004, the National Underground Railroad Freedom Center was completed along Freedom Way in Downtown, honoring the city's involvement in the Underground Railroad. In 1859, Cincinnati laid out six streetcar lines; the cars were pulled by horses and the lines made it easier for people to get around the city. By 1872, Cincinnatians could travel on

690-458: A population growth, marking the first such increase since the 1950 census. On January 4, 2022, Aftab Pureval assumed office as the 70th mayor of Cincinnati. Cincinnati has many nicknames , including Cincy, The Queen City, The Queen of the West, The Blue Chip City, and The City of Seven Hills. These are more typically associated with professional, academic, and public relations references to

759-933: A rivertown crossroads, depended on trade with the slave states south of the Ohio River at a time when thousands of black people were settling in the free state of Ohio. Most of them came after the American Civil War and were from Kentucky and Virginia with many of them fugitives who had sought freedom and work in the North. In the antebellum years, the majority of native-born whites in the city came from northern states, primarily Pennsylvania . Though 57 percent of whites migrated from free states, 26 percent were from southern states and they retained their cultural support for slavery. This quickly led to tensions between pro-slavery residents and abolitionists who sought lifting restrictions on free black people, as codified in

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828-458: A symbol of Roman civic virtue . Cincinnati began in 1788 when Mathias Denman, Colonel Robert Patterson , and Israel Ludlow landed at a spot at the northern bank of the Ohio opposite the mouth of the Licking and decided to settle there. The original surveyor, John Filson , named it "Losantiville", a combination of syllables drawn from French and Latin words, intended to mean "town opposite

897-578: Is 79 feet 11 + 7 ⁄ 8  inches (24.381 m), having crested January 26, 1937. Various parts of Cincinnati flood at different points: Riverbend Music Center in the California neighborhood floods at 42 feet (13 m), while Sayler Park floods at 71 feet (22 m) and the Freeman Avenue flood gate closes at 75 feet (23 m). Frequent flooding has hampered the growth of Cincinnati's municipal airport at Lunken Field and

966-535: Is $ 158,200, and the cost of living in Cincinnati is 8% below the national average. As of September 2022, the unemployment rate is 3.3%, below the national average. Several Fortune 500 companies are headquartered in Cincinnati, such as Kroger , Procter & Gamble , Western & Southern Financial Group , Fifth Third Bank , American Financial Group , and Cintas . General Electric has headquartered their Global Operations Center in Cincinnati; GE Aerospace

1035-477: Is already complete and 100 percent occupied as of early 2013. Smale Riverfront Park is being developed along with The Banks, and is Cincinnati's newest park. Nearly $ 3.5 billion have been invested in the urban core of Cincinnati (including Northern Kentucky). Much of this development has been undertaken by 3CDC . The Cincinnati Bell Connector began in September 2016. Cincinnati is midway by river between

1104-462: Is among the largest, most intact urban historic districts in the United States. Most of Over-the-Rhine's ornate brick buildings were built by German immigrants from 1865 to the 1880s. The neighborhood has been intensely redeveloped in the 21st century, with a focus on fostering small businesses. Cincinnati is at the southern limit (considering the 0 °C or 32 °F isotherm ) of the humid continental climate zone ( Köppen : Dfa ), bordering

1173-619: Is based in Evendale . The Kroger Company employs over 20,000 people locally, making it the largest employer in the city; the other four largest employers are Cincinnati Children's Hospital , TriHealth , the University of Cincinnati , and St. Elizabeth Healthcare . Cincinnati is home to a branch office of the Federal Reserve Bank of Cleveland . Cincinnati was platted and proliferated by American settlers , including Scotch Irish , frontiersmen , and keelboaters . For over

1242-690: Is home to numerous structures that are noteworthy due to their architectural characteristics or historic associations, including the aforementioned Carew Tower , the Scripps Center, the Ingalls Building , Cincinnati Union Terminal , and the Isaac M. Wise Temple . Queen City Square opened in January 2011. The building is the tallest in Cincinnati and the third tallest in Ohio, reaching a height of 665 feet (203 m). Since April 1, 1922,

1311-851: The 2015 MLB All-Star Fan Fest. The DECC was host to the 1977 National Rifle Association (NRA) annual convention, at which the Revolt at Cincinnati resulted in the election of Harlon Carter as the leader of the NRA, and a change in emphasis for the organization, away from hunting, conservation, and marksmanship and toward an uncompromising defense of the personal ownership of firearms for self-defense. 39°06′05″N 84°31′03″W  /  39.101314°N 84.517495°W  / 39.101314; -84.517495 Albert Sabin Albert Bruce Sabin ( / ˈ s eɪ b ɪ n / SAY -bin ; born Abram Saperstejn ; August 26, 1906 – March 3, 1993)

1380-463: The COVID-19 pandemic in the event that area hospitals reach capacity. Venue management company, ASM Global, oversees day-to-day operations of the 750,000-square-foot (70,000 m) facility. The Duke Energy Center played host to the 2012 World Choir Games when it hosted the opening and closing ceremonies, as well as the awards ceremonies of the games. In July 2015, the convention center hosted

1449-592: The Coney Island amusement park. Downtown Cincinnati is protected from flooding by the Serpentine Wall at Yeatman's Cove and another flood wall built into Fort Washington Way . Parts of Cincinnati also experience flooding from the Little Miami River and Mill Creek . Cincinnati consists of fifty-two neighborhoods. Many of these neighborhoods were once villages that have been annexed by

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1518-561: The Indiana counties of Dearborn , Franklin , Union , and Ohio . Metropolitan Cincinnati has the twenty-eighth largest economy in the United States and the fifth largest in the Midwest , after Chicago , Minneapolis–St. Paul , Detroit , and St. Louis . In 2016, it had the fastest-growing Midwestern economic capital. The gross domestic product for the region was $ 127 billion (~$ 160 billion in 2023) in 2015. The median home price

1587-731: The NIH campus in Bethesda, Maryland . With the menace of polio growing, Sabin and other researchers, most notably Jonas Salk in Pittsburgh and Hilary Koprowski and H. R. Cox in New York City and Philadelphia , sought a vaccine to prevent or mitigate the illness. This was complicated because there were multiple strains of the disease. In 1951, the National Foundation for Infantile Paralysis 's typing program confirmed

1656-581: The Public Health Service (PHS) to license his three strains of vaccine. While the PHS stalled, the USSR sent millions of doses of the oral vaccine to places with polio epidemics, such as Japan. Sabin's first oral poliovirus vaccine (OPV), for use against type 1 polioviruses, was licensed in the United States in 1961. His vaccines for type 2 and type 3 polioviruses were licensed in 1962. At first,

1725-658: The SS Lapland which sailed from Antwerp to the Port of New York . In 1930, he became a naturalized citizen of the United States and changed his name to Albert Bruce Sabin. He graduated from high school in Paterson, New Jersey . Sabin began university in a dentistry program, but was interested in virology and changed majors. He received a bachelor's degree in science in 1928 and a medical degree in 1931 from New York University . In 1983, Sabin developed calcification of

1794-602: The humid subtropical climate zone ( Cfa ). Summers are hot and humid, with significant rainfall in each month and highs reaching 90 °F (32 °C) or above on 21 days per year, often with high dew points and humidity. July is the warmest month, with a daily average temperature of 75.9 °F (24.4 °C). Winters tend to be cold and moderately snowy, with January, the coldest month, averaging at 30.8 °F (−0.7 °C). Lows reach 0 °F (−18 °C) on an average 2.6 nights yearly. An average winter will see around 22.1 inches (56 cm) of snowfall, contributing to

1863-419: The "Black Code" of 1804. In the pre-Civil War period, Cincinnati had been called "a Southern city on free soil". Volatile social conditions saw riots in 1829 , when many black people lost their homes and property. As the Irish entered the city in the late 1840s, they competed with black people at the lower levels of the economy. White-led riots against black people occurred in 1836 , when an abolitionist press

1932-597: The 1954 Nobel Prize in Physiology or Medicine . Sabin developed an oral vaccine based on mutant strains of polio virus that seemed to stimulate antibody production but not to cause paralysis. Recipients of his live attenuated oral vaccine included himself, family, and colleagues. Sabin's first clinical trials were carried out at the Chillicothe Ohio Reformatory in late 1954. From 1956–1960, he worked with Russian colleagues to perfect

2001-473: The 19th century, Cincinnati was among the top 10 U.S. cities by population . The city developed as a river town for cargo shipping by steamboats , located at the crossroads of the Northern and Southern United States, with fewer immigrants and less influence from Europe than East Coast cities in the same period. However, it received a significant number of German-speaking immigrants , who founded many of

2070-509: The Ohio flood stage at Cincinnati has officially been set at 52 feet (16 m), as measured from the John A. Roebling Suspension Bridge . At this depth, the pumping station at the mouth of Mill Creek is activated. From 1873 to 1898, the flood stage was 45 feet (14 m). From 1899 to March 31, 1922, it was 50 feet (15 m). The Ohio reached its lowest level, less than 2 feet (0.61 m), in 1881; conversely, its all-time high water mark

2139-628: The Rockefeller Institute for Medical Research (now Rockefeller University ). During this time, he developed an intense interest in research, especially in the area of infectious diseases . In 1939, he moved to Cincinnati Children's Hospital in Cincinnati, Ohio . During World War II, he was a lieutenant colonel in the U.S. Army Medical Corps and helped develop a vaccine against Japanese encephalitis . Maintaining his association with Children's Hospital, by 1946, he had also become

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2208-693: The United States and the fifth largest in the Midwest , home to several Fortune 500 companies including Kroger , Procter & Gamble , and Fifth Third Bank . It is home to three professional sports teams: the Cincinnati Reds of Major League Baseball ; the Cincinnati Bengals of the National Football League ; and FC Cincinnati of Major League Soccer ; it is also home to the Cincinnati Cyclones ,

2277-789: The cervical spine, which caused paralysis and intense pain. Sabin revealed in a television interview that the experience had made him decide to spend the rest of his life working on alleviating pain. This condition was successfully treated by surgery conducted at Johns Hopkins Hospital in 1992 when Sabin was 86. A year later, Sabin died in Washington, D.C. , from heart failure. Sabin trained in internal medicine, pathology, and surgery at Bellevue Hospital in New York City from 1931 to 1933. In 1934, he conducted research at The Lister Institute for Preventive Medicine in England, then joined

2346-468: The cities of Pittsburgh, Pennsylvania , and Cairo, Illinois . The downtown lies near the mouth of the Licking , a confluence where the first settlement occurred. Metro Cincinnati spans southern Ohio, southeastern Indiana, and northern Kentucky; the census bureau has measured the city proper at 79.54 square miles (206.01 km ), of which 77.94 square miles (201.86 km ) are land and 1.60 square miles (4.14 km ) are water. The city spreads over

2415-665: The city government completed the Cincinnati Southern Railway to Chattanooga, Tennessee . It was the only municipally-owned interstate railway in the United States until its sale to Norfolk Southern in March 2024. In 1884, outrage over a manslaughter verdict in what many observers thought was a clear case of murder triggered the Courthouse riots , one of the most destructive riots in American history. Over

2484-667: The city government does own several properties outside the corporation limits: French Park in Amberley Village and the disused runway at the former Blue Ash Airport in Blue Ash . Cincinnati has many landmarks across its area. Some of these landmarks are recognized nationwide, others are more recognized among locals. These landmarks include: Union Terminal , Carew Tower , Great American Tower , Fountain Square , Washington Park , and Great American Ballpark . Cincinnati

2553-504: The city itself. Subsequently, substantial transformations unfolded, particularly in the process of gentrification within the Over-the-Rhine neighborhood. In 2018, MLS announced the inclusion of FC Cincinnati , becoming the city's third professional sports team. TQL Stadium , located on Cincinnati's west end, was subsequently constructed and opened its doors in 2021. Notably, the 2020 census revealed that Cincinnati had witnessed

2622-550: The city was 48.4% male and 51.6% female. As of the 2022 census estimates , the Cincinnati metropolitan area had a population of 2,265,051, making it the 30th-largest metropolitan statistical area in the country. It includes the Ohio counties of Hamilton , Butler , Warren , Clermont , Clinton , and Brown , as well as the Kentucky counties of Boone , Bracken , Campbell , Gallatin , Grant , Kenton , and Pendleton , and

2691-446: The city was 50.3% White , 41.4% African American , 0.1% Native American , 2.2% Asian , 0.1% Pacific Islander , 1.2% from other races , and 4.6% from two or more races. Hispanic or Latino of any race were 4.2% of the population. There were 138,696 households, of which 25.4% had children under the age of 18 living with them, 23.2% were married couples living together, 19.1% had a female householder with no husband present, 4.4% had

2760-484: The city's cultural institutions. It later developed an industrialized economy in manufacturing. Many structures in the urban core have remained intact for 200 years; in the late 1800s, Cincinnati was commonly referred to as the " Paris of America" due mainly to ambitious architectural projects such as the Music Hall , Cincinnatian Hotel , and Roebling Bridge . Cincinnati has the twenty-eighth largest economy in

2829-549: The city, including restaurant names such as Blue Chip Cookies , and are not commonly used by locals in casual conversation, with the exception of Cincy, which is often used to refer to the city in absentia. "The City of Seven Hills" stems from the June 1853 edition of the West American Review , "Article III—Cincinnati: Its Relations to the West and South", which described and named seven specific hills. The hills form

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2898-580: The city, with many retaining their former names, such as Walnut Hills and Mount Auburn . Westwood is the city's most populous neighborhood, with other significant neighborhoods including CUF (home to the University of Cincinnati ) and Price Hill . Downtown Cincinnati is the city's central business district and contains a number of neighborhoods in the flat land between the Ohio River and uptown. These neighborhoods include Over-the-Rhine , Pendleton , Queensgate , and West End . Over-the-Rhine

2967-611: The city: And this Song of the Vine, This greeting of mine, The winds and the birds shall deliver, To the Queen of the West, In her garlands dressed, On the banks of the Beautiful River. For many years, Cincinnati was also known as "Porkopolis"; this nickname came from the city's large pork interests. Newer nicknames such as "The 'Nati" are emerging and are attempted to be used in different cultural contexts. For example,

3036-426: The course of three days, 56 people were killed and over 300 were injured. The riots ended the regime of Republican boss Thomas C. Campbell . At the beginning of the 20th century, Cincinnati had a population of 325,902. The city completed many ambitious projects in the 20th century starting with the Ingalls Building which was completed in 1903. An early rejuvenation of downtown began into the 1920s and continued into

3105-541: The dawn of the 2000s, Cincinnati's population stood at 331,285. The construction of Paul Brown Stadium (currently known as Paycor Stadium) in the year 2000 resulted from a sales tax increase in Hamilton County , as did the commencement of construction for Great American Ball Park , which later opened its doors in 2003. The city experienced the 2001 Cincinnati riots , causing an estimated $ 3.6 million in damage to businesses and $ 1.5–2 million in damage to

3174-627: The earlier vaccine developed by Salk in 1954, and its effects lasted longer. The Sabin vaccine became the predominant method of vaccination against polio in the United States for the next three decades. It broke the chain of transmission of the virus and allowed for the possibility that polio might one day be eradicated. Sabin also developed vaccines against other viral diseases, including encephalitis and dengue . In addition, he investigated possible links between viruses and some forms of cancer . Sabin refused to patent his vaccine, waiving commercial exploitation by pharmaceutical industries, so that

3243-408: The existence of three main serotypes of poliovirus, since known as type 1, type 2, and type 3. Salk developed an inactivated poliovirus vaccine (IPV), a "dead" vaccine given by injection, which was released for use in 1955. It was effective in preventing most of the complications of polio, but did not prevent the initial intestinal infection. By carrying out autopsies of polio victims, Sabin

3312-610: The fact that the two countries did not have formal diplomatic ties. In 1969–72, he lived in Israel , serving as president of Weizmann Institute of Science in Rehovot . After his return to the United States, he worked (1974–82) as a research professor at the Medical University of South Carolina . He later moved to the Washington, D.C. , area, where he was a resident scholar at the John E. Fogarty International Center on

3381-400: The field of vaccinology or a complementary field. Cincinnati, Ohio Cincinnati ( / ˌ s ɪ n s ɪ ˈ n æ t i / SIN -si- NAT -ee ; nicknamed Cincy ) is a city in and the county seat of Hamilton County, Ohio , United States. Settled by Europeans in 1788, the city is located on the northern side of the confluence of the Licking and Ohio rivers,

3450-452: The head of Pediatric Research at the University of Cincinnati . At Cincinnati's Children's Hospital, Sabin supervised the fellowship of Robert M. Chanock , whom he called his "star scientific son". Sabin went on a fact-finding trip to Cuba in 1967 to discuss with Cuban officials the possibility of establishing a collaborative relationship between the United States and Cuba through their respective national academies of sciences, in spite of

3519-561: The late 1840s. The city grew rapidly over the next two decades, reaching 115,000 people by 1850. During this period of rapid expansion and prominence, residents of Cincinnati began referring to the city as the Queen City. Cincinnati's location, on the border between the free state of Ohio and the slave state of Kentucky , made it a prominent location for slaves to escape the slave-owning south. Many prominent abolitionists also called Cincinnati their home during this period, and made it

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3588-433: The latter of which marks the state line with Kentucky . The population of Cincinnati was 309,317 in 2020, making it the third-most populous city in Ohio after Columbus and Cleveland and 64th in the United States . The city is the economic and cultural hub of the Cincinnati metropolitan area , Ohio's most populous metro area, and the nation's 30th-largest , with over 2.265 million residents. Throughout much of

3657-474: The local Keep America Beautiful affiliate, Keep Cincinnati Beautiful, introduced the catchphrase "Don't Trash the 'Nati" in 1998 as part of a litter -prevention campaign. The city is undergoing significant changes due to new development and private investment. This includes buildings of the long-stalled Banks project that includes apartments, retail, restaurants, and offices, which will stretch from Great American Ball Park to Paycor Stadium . Phase 1A

3726-604: The low price would guarantee a more extensive spread of the treatment. From the development of his vaccine Sabin did not gain a penny, and continued to live on his salary as a professor. The Sabin Vaccine Institute was founded in 1993 to continue the work of developing and promoting vaccines. To commemorate Sabin's pioneering work, the institute annually awards the Albert B. Sabin Gold Medal in recognition of work in

3795-482: The monovalent poliovirus vaccines were administered together by being put on a sugar cube , because the oral polio vaccine had a bitter, salty taste (inspiring Robert B. Sherman 's lyrics to A Spoonful of Sugar (Helps the Medicine Go Down) for the 1964 film Mary Poppins ). In 1964, a single trivalent OPV containing all three viral serotypes was approved. Sabin's oral vaccine was easier to give than

3864-555: The mouth of the Licking". On January 4, 1790, St. Clair changed the name of the settlement to honor the Society of the Cincinnati. In 1811, the introduction of steamboats on the Ohio River opened up the city's trade to more rapid shipping, and the city established commercial ties with St. Louis, Missouri , and New Orleans downriver. Cincinnati was incorporated as a city on March 1, 1819. Exporting pork products and hay, it became

3933-666: The next decade with the construction of Cincinnati Union Terminal , the United States Courthouse and Post Office , the Cincinnati Subway , and the 49- story Carew Tower , which was the city's tallest building upon its completion. Cincinnati weathered the Great Depression better than most American cities of its size, largely due to a resurgence in river trade, which was less expensive than transporting goods by rail. The Ohio River flood of 1937

4002-649: The next major form of commercial transportation to come to Cincinnati. In 1836, the Little Miami Railroad was chartered. Construction began soon after, to connect Cincinnati with the Mad River and Lake Erie Railroad, and provide access to the ports of the Sandusky Bay on Lake Erie . During the time, employers struggled to hire enough people to fill positions. The city had a labor shortage until large waves of immigration by Irish and Germans in

4071-428: The oral vaccine and prove its extraordinary effectiveness and safety. The Sabin vaccine worked in the intestines to block the poliovirus from entering the bloodstream. Between 1955 and 1961, the oral vaccine was tested on at least 100 million people in the USSR, parts of Eastern Europe, Singapore, Mexico, and the Netherlands. The first industrial production and mass use of oral poliovirus vaccine (OPV) from Sabin strains

4140-569: The population has begun recovering: the 2020 census reports a population of 309,317, representing a 4.2% increase from 296,943 in 2010. This marked the first increase in population recorded since the 1950 Census, reversing a 60-year trend of population decline. At the 2020 census, there were 309,317 people, 138,696 households, and 62,319 families residing in the city. The population density was 3,809.9 inhabitants per square mile (1,471.0/km ). There were 161,095 housing units at an average density of 2,066.9 per square mile (798.0/km ). The racial makeup of

4209-440: The streetcars within the city and transfer to rail cars for travel to the hill communities. The Cincinnati Inclined Plane Company began transporting people to the top of Mount Auburn that year.   In 1889, the Cincinnati streetcar system began converting its horse-drawn cars to electric streetcars . The Second Annual Meeting of the Woman's Christian Temperance Union was held in Cincinnati in November 1875. In 1880,

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4278-420: The suggestion of the surveyor Israel Ludlow , in honor of the Society of the Cincinnati . St. Clair was at the time president of the Society, made up of Continental Army officers of the Revolutionary War. The club was named for Lucius Quinctius Cincinnatus , a dictator in the early Roman Republic who saved Rome from a crisis and then retired to farming because he did not want to remain in power, becoming

4347-427: The warmer months, and tornadoes , while infrequent, are not unknown, with such events striking the Metro Cincinnati area most recently in 1974, 1999, 2012, and 2017. See or edit raw graph data . In 1950, Cincinnati reached its peak population of 503,998; thereafter, it lost population in every census count from 1960 to 2010. In the late 20th century, industrial restructuring caused a loss of jobs. More recently,

4416-510: The yearly 42.5 inches (1,080 mm) of precipitation, with rainfall peaking in spring. Extremes range from −25 °F (−32 °C) on January 18, 1977, up to 108 °F (42 °C) on July 21 and 22, 1934. While snow in Cincinnati is not as intense as many of the cities located closer to the Great Lakes, there have been notable cases of severe snowfall, including the Great Blizzard of 1978 , and more notable snowstorms in 1994, 1999 , 2007 , and 2021 . Severe thunderstorms are common in

4485-454: Was a Polish-American medical researcher, best known for developing the oral polio vaccine , which has played a key role in nearly eradicating the disease . In 1969–72, he served as the president of the Weizmann Institute of Science in Israel. Abram Saperstejn was born in Białystok , Russian Empire (before and since 1918 in Poland ), to Polish-Jewish parents, Jacob Saperstejn and Tillie Krugman. In 1921, he emigrated with his family on

4554-478: Was able to demonstrate that the poliovirus multiplied and attacked the intestines before it moved to the central nervous system. This also suggested that polio virus could be grown in other tissues besides embryonic brain tissue, leading to easier and cheaper methods of vaccine development. John Enders , Thomas Huckle Weller , and Frederick Robbins would successfully grow poliovirus in laboratory cultures of non-nerve tissue in 1949, an achievement that earned them

4623-423: Was also important. The first established Methodist class in the Northwest Territory came 1797 to nearby Milford . By 1879, there were 162 documented church edifices in the city. For this reason, from the beginning, Protestantism has played a formative role in the Cincinnati ethos. Christ Church Cathedral continues the legacy of the early Anglican leaders of Cincinnati, noted by historical associations as being

4692-519: Was one of the worst in the nation's history and destroyed many areas along the Ohio valley. Afterward the city built protective flood walls . After World War II , Cincinnati unveiled a master plan for urban renewal that resulted in modernization of the inner city. During the 1950s, Cincinnati's population peaked at 509,998. Since the 1950s, $ 250 million has been spent on improving neighborhoods, building clean and safe low- and moderate-income housing, providing jobs and stimulating economic growth. At

4761-487: Was organized by Soviet scientist Mikhail Chumakov . This provided the critical impetus for allowing large-scale clinical trials of OPV in the United States in April 1960 on 180,000 Cincinnati school children. The mass immunization techniques that Sabin pioneered with his associates effectively eradicated polio in Cincinnati. Against considerable opposition from the March of Dimes Foundation, which supported use of Salk's relatively effective killed vaccine, Sabin prevailed on

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