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91-411: This is a demography of the population of Andorra , including population density , ethnicity , education level, health of the populace, economic status, religious affiliations and other aspects of the population. Andorrans are a minority in their own country; Spanish , French , and Portuguese residents make up 67.7% of the population. The national language is Catalan , a Romance language in

182-455: A fetus with a blood type which is different from her own. Typically, this is an issue if a Rh- mother has a child with a Rh+ father, and the fetus ends up being Rh+ like the father. In those cases, the mother can make IgG blood group antibodies. This can happen if some of the fetus' blood cells pass into the mother's blood circulation (e.g. a small fetomaternal hemorrhage at the time of childbirth or obstetric intervention), or sometimes after

273-694: A microscope . If agglutination occurs, that particular donor's blood cannot be transfused to that particular recipient. In a blood bank it is vital that all blood specimens are correctly identified, so labelling has been standardized using a barcode system known as ISBT 128 . The blood group may be included on identification tags or on tattoos worn by military personnel, in case they should need an emergency blood transfusion. Frontline German Waffen-SS had blood group tattoos during World War II . Rare blood types can cause supply problems for blood banks and hospitals. For example, Duffy -negative blood occurs much more frequently in people of African origin, and

364-468: A significant comparison, numbers must be altered for the size of the population that is under study. For example, the fertility rate is calculated as the ratio of the number of births to women of childbearing age to the total number of women in this age range. If these adjustments were not made, we would not know if a nation with a higher rate of births or deaths has a population with more women of childbearing age or more births per eligible woman. Within

455-425: A blood bank would be suitable for a recipient who may be D positive or D negative, as long as blood plasma and the recipient are ABO compatible. In transfusions of packed red blood cells, individuals with type O Rh D negative blood are often called universal donors. Those with type AB Rh D positive blood are called universal recipients. However, these terms are only generally true with respect to possible reactions of

546-431: A blood sample to a solution containing antibodies corresponding to each antigen. The presence of an antigen on the surface of the blood cells is indicated by agglutination . In addition to the current practice of serologic testing of blood types, the progress in molecular diagnostics allows the increasing use of blood group genotyping. In contrast to serologic tests reporting a direct blood type phenotype, genotyping allows

637-401: A country (or other entity) contains Population t persons at time t . What is the size of the population at time t + 1 ? Natural increase from time t to t + 1: Net migration from time t to t + 1: These basic equations can also be applied to subpopulations. For example, the population size of ethnic groups or nationalities within a given society or country is subject to

728-484: A field of sociology , though there are a number of independent demography departments. These methods have primarily been developed to study human populations, but are extended to a variety of areas where researchers want to know how populations of social actors can change across time through processes of birth, death, and migration . In the context of human biological populations, demographic analysis uses administrative records to develop an independent estimate of

819-426: A major bleed when stocks of D-negative blood units are very low at the blood bank, D-positive blood might be given to D-negative females above child-bearing age or to Rh-negative males, providing that they did not have anti-D antibodies, to conserve D-negative blood stock in the blood bank. The converse is not true; Rh D-positive patients do not react to D negative blood. This same matching is done for other antigens of

910-460: A new product, and to analyze certain dynamics of a company's workforce. Choosing a new location for a branch of a bank, choosing the area in which to start a new supermarket, consulting a bank loan officer that a particular location would be a beneficial site to start a car wash, and determining what shopping area would be best to buy and be redeveloped in metropolis area are types of problems in which demographers can be called upon. Standardization

1001-498: A period of transition where in demography emerged from statistics as a separate field of interest. This period included a panoply of international 'great demographers' like Adolphe Quetelet (1796–1874), William Farr (1807–1883), Louis-Adolphe Bertillon (1821–1883) and his son Jacques (1851–1922), Joseph Körösi (1844–1906), Anders Nicolas Kaier (1838–1919), Richard Böckh (1824–1907), Émile Durkheim (1858–1917), Wilhelm Lexis (1837–1914), and Luigi Bodio (1840–1920) contributed to

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1092-441: A person receives bone marrow from someone of a different ABO type (e.g., a type O patient receives a type A bone marrow), the patient's blood type should eventually become the donor's type, as the patient's hematopoietic stem cells (HSCs) are destroyed, either by ablation of the bone marrow or by the donor's T-cells. Once all the patient's original red blood cells have died, they will have been fully replaced by new cells derived from

1183-450: A potential donor is found to have anti-D antibodies or any strong atypical blood group antibody by antibody screening in the blood bank, they would not be accepted as a donor (or in some blood banks the blood would be drawn but the product would need to be appropriately labeled); therefore, donor blood plasma issued by a blood bank can be selected to be free of D antibodies and free of other atypical antibodies, and such donor plasma issued from

1274-444: A result of transfusion. For transfusions of plasma , this situation is reversed. Type O plasma, containing both anti-A and anti-B antibodies, can only be given to O recipients. The antibodies will attack the antigens on any other blood type. Conversely, AB plasma can be given to patients of any ABO blood group, because it does not contain any anti-A or anti-B antibodies. Typically, blood type tests are performed through addition of

1365-574: A sensitizing event: possibly a fetomaternal transfusion of blood from a fetus in pregnancy or occasionally a blood transfusion with D positive RBCs . Rh disease can develop in these cases. Rh negative blood types are much less common in Asian populations (0.3%) than they are in European populations (15%). The presence or absence of the Rh(D) antigen is signified by the + or − sign, so that, for example,

1456-410: A similar way as medicines. Much of the routine work of a blood bank involves testing blood from both donors and recipients to ensure that every individual recipient is given blood that is compatible and as safe as possible. If a unit of incompatible blood is transfused between a donor and recipient, a severe acute hemolytic reaction with hemolysis (RBC destruction), kidney failure and shock

1547-426: A standardized mortality rate (SMR) or standardized incidence rate (SIR). Population change is analyzed by measuring the change between one population size to another. Global population continues to rise, which makes population change an essential component to demographics. This is calculated by taking one population size minus the population size in an earlier census . The best way of measuring population change

1638-470: A therapeutic blood transfusion . This can cause Rh disease or other forms of hemolytic disease of the newborn (HDN) in the current pregnancy and/or subsequent pregnancies. Sometimes this is lethal for the fetus; in these cases it is called hydrops fetalis . If a pregnant woman is known to have anti-D antibodies, the Rh blood type of a fetus can be tested by analysis of fetal DNA in maternal plasma to assess

1729-481: A total of 45 human blood group systems are recognized by the International Society of Blood Transfusion (ISBT). The two most important blood group systems are ABO and Rh ; they determine someone's blood type (A, B, AB, and O, with + or − denoting RhD status) for suitability in blood transfusion . A complete blood type would describe each of the 45 blood groups, and an individual's blood type

1820-556: A transfusion of D-positive blood once, but this would cause sensitization to the D antigen, and a female patient would become at risk for hemolytic disease of the newborn . If a D-negative patient has developed anti-D antibodies, a subsequent exposure to D-positive blood would lead to a potentially dangerous transfusion reaction. Rh D-positive blood should never be given to D-negative women of child-bearing age or to patients with D antibodies, so blood banks must conserve Rh-negative blood for these patients. In extreme circumstances, such as for

1911-499: A variety of demographic methods for modelling population processes. They include models of mortality (including the life table , Gompertz models , hazards models , Cox proportional hazards models , multiple decrement life tables , Brass relational logits), fertility (Hermes model, Coale -Trussell models, parity progression ratios ), marriage (Singulate Mean at Marriage, Page model), disability ( Sullivan's method , multistate life tables), population projections ( Lee-Carter model ,

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2002-446: Is a comparison of clinically relevant characteristics of antibodies against the main human blood group systems: Transfusion medicine is a specialized branch of hematology that is concerned with the study of blood groups, along with the work of a blood bank to provide a transfusion service for blood and other blood products. Across the world, blood products must be prescribed by a medical doctor (licensed physician or surgeon ) in

2093-543: Is a useful demographic technique used in the analysis of a business. It can be used as an interpretive and analytic tool for the comparison of different markets. These organizations have interests about the number and characteristics of their clients so they can maximize the sale of their products, their outlook on their influence, or the ends of their power, services, and beneficial works. Blood type Blood types are inherited and represent contributions from both parents of an individual. As of 31 December 2023,

2184-417: Is because developed countries have proportionally more older people, who are more likely to die in a given year, so that the overall mortality rate can be higher even if the mortality rate at any given age is lower. A more complete picture of mortality is given by a life table , which summarizes mortality separately at each age. A life table is necessary to give a good estimate of life expectancy. Suppose that

2275-535: Is called autotransfusion , which is always compatible with the patient. The procedure of washing a patient's own red blood cells goes as follows: The patient's lost blood is collected and washed with a saline solution. The washing procedure yields concentrated washed red blood cells. The last step is reinfusing the packed red blood cells into the patient. There are multiple ways to wash red blood cells. The two main ways are centrifugation and filtration methods. This procedure can be performed with microfiltration devices like

2366-593: Is different in that it agglutinates with both A and B. This was the discovery of blood groups for which Landsteiner was awarded the Nobel Prize in Physiology or Medicine in 1930. (C was later renamed to O after the German Ohne , meaning without, or zero, or null. ) Another group (later named AB) was discovered a year later by Landsteiner's students Adriano Sturli and Alfred von Decastello without designating

2457-431: Is likely to continue to rise. Populations can change through three processes: fertility, mortality, and migration. Fertility involves the number of children that women have and is to be contrasted with fecundity (a woman's childbearing potential). Mortality is the study of the causes, consequences, and measurement of processes affecting death to members of the population. Demographers most commonly study mortality using

2548-407: Is likely to occur, and death is a possibility. Antibodies can be highly active and can attack RBCs and bind components of the complement system to cause massive hemolysis of the transfused blood. Patients should ideally receive their own blood or type-specific blood products to minimize the chance of a transfusion reaction . It is also possible to use the patient's own blood for transfusion. This

2639-461: Is one of many possible combinations of blood-group antigens. Almost always, an individual has the same blood group for life, but very rarely an individual's blood type changes through addition or suppression of an antigen in infection , malignancy , or autoimmune disease . Another more common cause of blood type change is a bone marrow transplant . Bone-marrow transplants are performed for many leukemias and lymphomas , among other diseases. If

2730-522: Is quick-frozen to retain the labile clotting factors V and VIII , which are usually administered to patients who have a potentially fatal clotting problem caused by a condition such as advanced liver disease, overdose of anticoagulant , or disseminated intravascular coagulation (DIC). Units of packed red cells are made by removing as much of the plasma as possible from whole blood units. Clotting factors synthesized by modern recombinant methods are now in routine clinical use for hemophilia , as

2821-574: Is related to inborn differences between individuals or it is the result of some damage of bacterial kind. This was the first evidence that blood variation exists in humans. The next year, in 1901, he made a definitive observation that blood serum of an individual would agglutinate with only those of certain individuals. Based on this he classified human bloods into three groups, namely group A, group B, and group C. He defined that group A blood agglutinates with group B, but never with its own type. Similarly, group B blood agglutinates with group A. Group C blood

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2912-550: Is seen as the intellectual father of ideas of overpopulation and the limits to growth. Later, more sophisticated and realistic models were presented by Benjamin Gompertz and Verhulst . In 1855, a Belgian scholar Achille Guillard defined demography as the natural and social history of human species or the mathematical knowledge of populations, of their general changes, and of their physical, civil, intellectual, and moral condition. The period 1860–1910 can be characterized as

3003-400: Is that a person's ABO blood type is predictive of their personality , character , and compatibility with others . Researchers have established no scientific basis exists for blood type personality categorization, and studies have found no "significant relationship between personality and blood type, rendering the theory 'obsolete' and concluding that no basis exists to assume that personality

3094-473: Is the statistical study of human populations : their size, composition (e.g., ethnic group, age), and how they change through the interplay of fertility (births), mortality (deaths), and migration. Demographic analysis examines and measures the dimensions and dynamics of populations; it can cover whole societies or groups defined by criteria such as education , nationality , religion , and ethnicity . Educational institutions usually treat demography as

3185-554: Is the case in much of the developing world, and most of historical demography . One of these techniques in contemporary demography is the sister method, where survey researchers ask women how many of their sisters have died or had children and at what age. With these surveys, researchers can then indirectly estimate birth or death rates for the entire population. Other indirect methods in contemporary demography include asking people about siblings, parents, and children. Other indirect methods are necessary in historical demography. There are

3276-517: Is the second most significant blood-group system in human-blood transfusion with currently 50 antigens. The most significant Rh antigen is the D antigen, because it is the most likely to provoke an immune system response of the five main Rh antigens. It is common for D-negative individuals not to have any anti-D IgG or IgM antibodies, because anti-D antibodies are not usually produced by sensitization against environmental substances. However, D-negative individuals can produce IgG anti-D antibodies following

3367-432: Is today widely taught in many universities across the world, attracting students with initial training in social sciences, statistics or health studies. Being at the crossroads of several disciplines such as sociology , economics , epidemiology , geography , anthropology and history , demography offers tools to approach a large range of population issues by combining a more technical quantitative approach that represents

3458-510: Is used in a wide variety of contexts. For example, it is often used in business plans, to describe the population connected to the geographic location of the business. Demographic analysis is usually abbreviated as DA. For the 2010 U.S. Census, The U.S. Census Bureau has expanded its DA categories. Also as part of the 2010 U.S. Census, DA now also includes comparative analysis between independent housing estimates, and census address lists at different key time points. Patient demographics form

3549-421: Is using the intercensal percentage change. The intercensal percentage change is the absolute change in population between the censuses divided by the population size in the earlier census. Next, multiply this a hundredfold to receive a percentage . When this statistic is achieved, the population growth between two or more nations that differ in size, can be accurately measured and examined. For there to be

3640-807: The International Union for the Scientific Study of Population , or a national association such as the Population Association of America in the United States, or affiliates of the Federation of Canadian Demographers in Canada . Population composition is the description of population defined by characteristics such as age, race , sex or marital status . These descriptions can be necessary for understanding

3731-666: The Leslie Matrix ), and population momentum ( Keyfitz ). The United Kingdom has a series of four national birth cohort studies, the first three spaced apart by 12 years: the 1946 National Survey of Health and Development , the 1958 National Child Development Study , the 1970 British Cohort Study , and the Millennium Cohort Study , begun much more recently in 2000. These have followed the lives of samples of people (typically beginning with around 17,000 in each study) for many years, and are still continuing. As

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3822-516: The Middle Ages , Christian thinkers devoted much time in refuting the Classical ideas on demography. Important contributors to the field were William of Conches , Bartholomew of Lucca , William of Auvergne , William of Pagula , and Muslim sociologists like Ibn Khaldun . One of the earliest demographic studies in the modern period was Natural and Political Observations Made upon

3913-626: The Rockefeller Institute for Medical Research in New York, and as a member of a committee of the National Research Council concerned with blood grouping suggested to substitute Janský's and Moss's systems with the letters O, A, B, and AB, first instroduced by Polish physician Ludwik Hirszfeld and German physician Emil von Dungern . There was another confusion on the use of O which was introduced in 1910. It

4004-572: The United States and much of Europe ), registry statistics are the best method for estimating the number of births and deaths. A census is the other common direct method of collecting demographic data. A census is usually conducted by a national government and attempts to enumerate every person in a country. In contrast to vital statistics data, which are typically collected continuously and summarized on an annual basis, censuses typically occur only every 10 years or so, and thus are not usually

4095-653: The Western Romance group. It is spoken by more than 9 million people in the nearby territories of Spain and France . Spanish , French , and Portuguese are also spoken. Andorrans live in seven urbanized valleys that form Andorra's political districts, the seven parròquies (parishes): The latest population figure (dec. 2023) of Andorra is 85,101. From state sources: Demographics Demography (from Ancient Greek δῆμος ( dêmos )  'people, society' and -γραφία ( -graphía )  'writing, drawing, description')

4186-666: The life table , a statistical device that provides information about the mortality conditions (most notably the life expectancy) in the population. Migration refers to the movement of persons from a locality of origin to a destination place across some predefined, political boundary. Migration researchers do not designate movements 'migrations' unless they are somewhat permanent. Thus, demographers do not consider tourists and travellers to be migrating. While demographers who study migration typically do so through census data on place of residence, indirect sources of data including tax forms and labour force surveys are also important. Demography

4277-433: The social dynamics from historical and comparative research. This data is often compared using a population pyramid . Population composition is also a very important part of historical research. Information ranging back hundreds of years is not always worthwhile, because the numbers of people for which data are available may not provide the information that is important (such as population size ). Lack of information on

4368-751: The Application of Probabilities to Life Contingencies (1838). In 1755, Benjamin Franklin published his essay Observations Concerning the Increase of Mankind, Peopling of Countries, etc. , projecting exponential growth in British colonies . His work influenced Thomas Robert Malthus , who, writing at the end of the 18th century, feared that, if unchecked, population growth would tend to outstrip growth in food production, leading to ever-increasing famine and poverty (see Malthusian catastrophe ). Malthus

4459-569: The A− group is ABO type A and does not have the Rh (D) antigen. As with many other genetic traits, the distribution of ABO and Rh blood groups varies significantly between populations. While theories are still debated in the scientific community as to why blood types vary geographically and why they emerged in the first place, evidence suggests that the evolution of blood types may be driven by genetic selection for those types whose antigens confer resistance to particular diseases in certain regions – such as

4550-564: The Bills of Mortality (1662) by John Graunt , which contains a primitive form of life table . Among the study's findings were that one-third of the children in London died before their sixteenth birthday. Mathematicians, such as Edmond Halley , developed the life table as the basis for life insurance mathematics. Richard Price was credited with the first textbook on life contingencies published in 1771, followed later by Augustus De Morgan , On

4641-483: The Hemoclear filter. Risks can be further reduced by cross-matching blood, but this may be skipped when blood is required for an emergency. Cross-matching involves mixing a sample of the recipient's serum with a sample of the donor's red blood cells and checking if the mixture agglutinates , or forms clumps. If agglutination is not obvious by direct vision, blood bank technologist usually check for agglutination with

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4732-661: The Pathological-Anatomical Institute of the University of Vienna (now Medical University of Vienna ). In 1900, he found that blood sera from different persons would clump together (agglutinate) when mixed in test tubes, and not only that, some human blood also agglutinated with animal blood. He wrote a two-sentence footnote: The serum of healthy human beings not only agglutinates animal red cells, but also often those of human origin, from other individuals. It remains to be seen whether this appearance

4823-887: The Rh system as C, c, E and e and for other blood group systems with a known risk for immunization such as the Kell system in particular for females of child-bearing age or patients with known need for many transfusions. Blood plasma compatibility is the inverse of red blood cell compatibility. Type AB plasma carries neither anti-A nor anti-B antibodies and can be transfused to individuals of any blood group; but type AB patients can only receive type AB plasma. Type O carries both antibodies, so individuals of blood group O can receive plasma from any blood group, but type O plasma can be used only by type O recipients. Table note 1. Assuming absence of strong atypical antibodies in donor plasma Rh D antibodies are uncommon, so generally neither D negative nor D positive blood contain anti-D antibodies. If

4914-468: The antibody A and antigen B agglutinates the antibody B). Thus, transfusion can be considered safe as long as the serum of the recipient does not contain antibodies for the blood cell antigens of the donor. The ABO system is the most important blood-group system in human-blood transfusion. The associated anti-A and anti-B antibodies are usually immunoglobulin M , abbreviated IgM , antibodies. It has been hypothesized that ABO IgM antibodies are produced in

5005-467: The basic demographic equation holds true by definition, in practice the recording and counting of events (births, deaths, immigration, emigration) and the enumeration of the total population size are subject to error. So allowance needs to be made for error in the underlying statistics when any accounting of population size or change is made. The figure in this section shows the latest (2004) UN ( United Nations ) WHO projections of world population out to

5096-696: The best source of data on births and deaths. Analyses are conducted after a census to estimate how much over or undercounting took place. These compare the sex ratios from the census data to those estimated from natural values and mortality data. Censuses do more than just count people. They typically collect information about families or households in addition to individual characteristics such as age, sex, marital status, literacy/education, employment status, and occupation, and geographical location. They may also collect data on migration (or place of birth or of previous residence), language, religion, nationality (or ethnicity or race), and citizenship. In countries in which

5187-518: The category of standardization , there are two major approaches: direct standardization and indirect standardization. A stable population does not necessarily remain fixed in size. It can be expanding or shrinking. The crude death rate as defined above and applied to a whole population can give a misleading impression. For example, the number of deaths per 1,000 people can be higher in developed nations than in less-developed countries, despite standards of health being better in developed countries. This

5278-458: The classification of blood groups has been generally accepted, and recommends that this nomenclature shall be adopted for international use as follows: 0 A B AB. To facilitate the change from the nomenclature hitherto employed the following is suggested: This classification became widely accepted and after the early 1950s it was universally followed. Hirszfeld and Dungern discovered the inheritance of blood types as Mendelian genetics in 1910 and

5369-553: The core of the data for any medical institution, such as patient and emergency contact information and patient medical record data. They allow for the identification of a patient and their categorization into categories for the purpose of statistical analysis. Patient demographics include: date of birth , gender , date of death , postal code, ethnicity, blood type , emergency contact information, family doctor, insurance provider data, allergies , major diagnoses and major medical history. Formal demography limits its object of study to

5460-498: The core of the discipline with many other methods borrowed from social or other sciences. Demographic research is conducted in universities, in research institutes, as well as in statistical departments and in several international agencies. Population institutions are part of the CICRED (International Committee for Coordination of Demographic Research) network while most individual scientists engaged in demographic research are members of

5551-528: The development of demography and to the toolkit of methods and techniques of demographic analysis. Demography is the statistical and mathematical study of the size, composition, and spatial distribution of human populations and how these features change over time. Data are obtained from a census of the population and from registries: records of events like birth , deaths , migrations, marriages, divorces , diseases, and employment . To do this, there needs to be an understanding of how they are calculated and

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5642-649: The distribution and abundance of organisms. As it relates to organizations and demography, organizations go through various liabilities to their continued survival. Hospitals, like all other large and complex organizations are impacted in the environment they work. For example, a study was done on the closure of acute care hospitals in Florida between a particular time. The study examined effect size, age, and niche density of these particular hospitals. A population theory says that organizational outcomes are mostly determined by environmental factors . Among several factors of

5733-699: The donor HSCs. Provided the donor had a different ABO type, the new cells' surface antigens will be different from those on the surface of the patient's original red blood cells. Some blood types are associated with inheritance of other diseases; for example, the Kell antigen is sometimes associated with McLeod syndrome . For another example, Von Willebrand disease may be more severe or apparent in people with blood type O. Certain blood types may affect susceptibility to infections. For example, people with blood type O may be less susceptible to pro-thrombotic events induced by COVID-19 or long covid . Another example being

5824-880: The existence of sub-types of A in 1911. In 1927, Landsteiner, with Philip Levine , discovered the MN blood group system , and the P system . Development of the Coombs test in 1945, the advent of transfusion medicine , and the understanding of ABO hemolytic disease of the newborn led to discovery of more blood groups. As of October 2024 , the International Society of Blood Transfusion (ISBT) recognizes 47 blood groups. A popular pseudoscientific belief in Eastern Asian countries (especially in Japan and South Korea ) known as 血液型 ketsuekigata / hyeoraekhyeong

5915-590: The existence of two systems immediately created confusion and potential danger in medical practice. Moss's system was adopted in Britain, France, and the US, while Janský's was preferred in most other European countries and some parts of the US. It was reported that "The practically universal use of the Moss classification at that time was completely and purposely cast aside. Therefore in place of bringing order out of chaos, chaos

6006-408: The family. The causes of turnover can be split into two separate factors, one linked with the culture of the organization, and the other relating to all other factors. People who do not fully accept a culture might leave voluntarily. Or, some individuals might leave because they fail to fit in and fail to change within a particular organization. A basic definition of population ecology is a study of

6097-453: The first years of life by sensitization to environmental substances such as food, bacteria , and viruses , although blood group compatibility rules are applied to newborn and infants as a matter of practice. The original terminology used by Karl Landsteiner in 1901 for the classification was A/B/C; in later publications "C" became "O". Type O is often called 0 ( zero , or null ) in other languages. The Rh system (Rh meaning Rhesus )

6188-418: The measurement of population processes, while the broader field of social demography or population studies also analyses the relationships between economic, social, institutional, cultural, and biological processes influencing a population. Demographic thoughts traced back to antiquity, and were present in many civilisations and cultures, like Ancient Greece , Ancient Rome , China and India . Made up of

6279-621: The name (simply referring it to as "no particular type"). Thus, after Landsteiner, three blood types were initially recognised, namely A, B, and C. Czech serologist Jan Janský was the first to recognise and designate four blood types in 1907 that he published in a local journal, using the Roman numerical I, II, III, and IV (corresponding to modern O, A, B, and AB respectively). Unknown to Janský, American physician William L. Moss introduced an almost identical classification in 1910, but with Moss's I and IV corresponding to Janský's IV and I. Thus

6370-413: The nation will become a nation of immigrants. This influx is projected to rise over the next century as new immigrants and their children will account for over half the U.S. population. These demographic shifts could ignite major adjustments in the economy, more specifically, in labor markets. People decide to exit organizations for many reasons, such as, better jobs, dissatisfaction, and concerns within

6461-458: The original data-collection procedures may prevent accurate evaluation of data quality. The demographic analysis of labor markets can be used to show slow population growth, population aging , and the increased importance of immigration. The U.S. Census Bureau projects that in the next 100 years, the United States will face some dramatic demographic changes. The population is expected to grow more slowly and age more rapidly than ever before and

6552-549: The plasma fraction of a blood transfusion may carry donor antibodies not found in the recipient, a significant reaction is unlikely because of dilution. Additionally, red blood cell surface antigens other than A, B and Rh D, might cause adverse reactions and sensitization, if they can bind to the corresponding antibodies to generate an immune response. Transfusions are further complicated because platelets and white blood cells (WBCs) have their own systems of surface antigens, and sensitization to platelet or WBC antigens can occur as

6643-528: The population. Demographic analysis estimates are often considered a reliable standard for judging the accuracy of the census information gathered at any time. In the labor force , demographic analysis is used to estimate sizes and flows of populations of workers; in population ecology the focus is on the birth, death, migration and immigration of individuals in a population of living organisms, alternatively, in social human sciences could involve movement of firms and institutional forms. Demographic analysis

6734-420: The prediction of a phenotype based on the knowledge of the molecular basis of the currently known antigens. This allows a more detailed determination of the blood type and therefore a better match for transfusion, which can be crucial in particular for patients with needs for many transfusions to prevent allo-immunization. Blood types were first discovered by an Austrian physician, Karl Landsteiner , working at

6825-516: The prefix demo- and the suffix -graphy , the term demography refers to the overall study of population. In ancient Greece, this can be found in the writings of Herodotus , Thucydides , Hippocrates , Epicurus , Protagoras , Polus , Plato and Aristotle . In Rome, writers and philosophers like Cicero , Seneca , Pliny the Elder , Marcus Aurelius , Epictetus , Cato , and Columella also expressed important ideas on this ground. In

6916-578: The prevalence of blood type O in malaria-endemic countries where individuals of blood type O exhibit the highest rates of survival. As of 31 December 2022, 42 blood-group systems have been identified by the International Society for Blood Transfusion in addition to the ABO and Rh systems. Thus, in addition to the ABO antigens and Rh antigens, many other antigens are expressed on the RBC surface membrane. For example, an individual can be AB, D positive, and at

7007-566: The questions they answer which are included in these four concepts: population change , standardization of population numbers, the demographic bookkeeping equation, and population composition. There are two types of data collection —direct and indirect—with several methods of each type. Direct data comes from vital statistics registries that track all births and deaths as well as certain changes in legal status such as marriage, divorce, and migration (registration of place of residence). In developed countries with good registration systems (such as

7098-409: The rarity of this blood type in the rest of the population can result in a shortage of Duffy-negative blood for these patients. Similarly, for RhD negative people there is a risk associated with travelling to parts of the world where supplies of RhD negative blood are rare, particularly East Asia , where blood services may endeavor to encourage Westerners to donate blood. A pregnant woman may carry

7189-558: The recipient's anti-A and anti-B antibodies to transfused red blood cells, and also possible sensitization to Rh D antigens. One exception is individuals with hh antigen system (also known as the Bombay phenotype) who can only receive blood safely from other hh donors, because they form antibodies against the H antigen present on all red blood cells. Blood donors with exceptionally strong anti-A, anti-B or any atypical blood group antibody may be excluded from blood donation. In general, while

7280-486: The red blood cells and the antibodies in the serum . Regarding the antigen property of the blood all human beings can be classified into four groups, those with antigen A (group A), those with antigen B (group B), those with both antigen A and B (group AB) and those with neither antigen (group O). The antibodies present together with the antigens are found as follows: There is an agglutination reaction between similar antigen and antibody (for example, antigen A agglutinates

7371-513: The resistance to specific malaria species seen in individuals lacking the Duffy antigen . The Duffy antigen, presumably as a result of natural selection , is less common in population groups from areas having a high incidence of malaria. The ABO blood group system involves two antigens and two antibodies found in human blood. The two antigens are antigen A and antigen B. The two antibodies are antibody A and antibody B. The antigens are present on

7462-672: The risk to the fetus of Rh disease. One of the major advances of twentieth century medicine was to prevent this disease by stopping the formation of Anti-D antibodies by D negative mothers with an injectable medication called Rho(D) immune globulin . Antibodies associated with some blood groups can cause severe HDN, others can only cause mild HDN and others are not known to cause HDN. To provide maximum benefit from each blood donation and to extend shelf-life, blood banks fractionate some whole blood into several products. The most common of these products are packed RBCs, plasma , platelets , cryoprecipitate , and fresh frozen plasma (FFP). FFP

7553-403: The risks of infection transmission that occur with pooled blood products are avoided. Table note 1. Assumes absence of atypical antibodies that would cause an incompatibility between donor and recipient blood, as is usual for blood selected by cross matching. An Rh D-negative patient who does not have any anti-D antibodies (never being previously sensitized to D-positive RBCs) can receive

7644-417: The same sources of change. When dealing with ethnic groups, however, "net migration" might have to be subdivided into physical migration and ethnic reidentification ( assimilation ). Individuals who change their ethnic self-labels or whose ethnic classification in government statistics changes over time may be thought of as migrating or moving from one population subcategory to another. More generally, while

7735-473: The same time M and N positive ( MNS system ), K positive ( Kell system ), Le or Le negative ( Lewis system ), and so on, being positive or negative for each blood group system antigen. Many of the blood group systems were named after the patients in whom the corresponding antibodies were initially encountered. Blood group systems other than ABO and Rh pose a potential, yet relatively low, risk of complications upon mixing of blood from different people. Following

7826-447: The samples have been drawn in a nationally representative way, inferences can be drawn from these studies about the differences between four distinct generations of British people in terms of their health, education, attitudes, childbearing and employment patterns. Indirect standardization is used when a population is small enough that the number of events (births, deaths, etc.) are also small. In this case, methods must be used to produce

7917-404: The theory, there are four that apply to the hospital closure example: size, age, density of niches in which organizations operate, and density of niches in which organizations are established. Problems in which demographers may be called upon to assist business organizations are when determining the best prospective location in an area of a branch store or service outlet, predicting the demand for

8008-478: The vital registration system may be incomplete, the censuses are also used as a direct source of information about fertility and mortality; for example, the censuses of the People's Republic of China gather information on births and deaths that occurred in the 18 months immediately preceding the census. Indirect methods of collecting data are required in countries and periods where full data are not available, such as

8099-533: The year 2150 (red = high, orange = medium, green = low). The UN "medium" projection shows world population reaching an approximate equilibrium at 9 billion by 2075. Working independently, demographers at the International Institute for Applied Systems Analysis in Austria expect world population to peak at 9 billion by 2070. Throughout the 21st century, the average age of the population

8190-657: Was increased in the larger cities." To resolve the confusion, the American Association of Immunologists , the Society of American Bacteriologists , and the Association of Pathologists and Bacteriologists made a joint recommendation in 1921 that the Jansky classification be adopted based on priority. But it was not followed particularly where Moss's system had been used. In 1927, Landsteiner, who had moved to

8281-649: Was never clear whether it was meant for the figure 0, German null for zero or the upper case letter O for ohne , meaning without; Landsteiner chose the latter. In 1928 the Permanent Commission on Biological Standardization adopted Landsteiner's proposal and stated: The Commission learns with satisfaction that, on the initiative of the Health Organization of the League of Nations, the nomenclature proposed by von Dungern and Hirszfeld for

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