Misplaced Pages

#43956

172-425: Torrey has conducted numerous research studies, particularly on possible infectious causes of schizophrenia. He has become well known as an advocate of the idea that severe mental illness, psychosis , is due to biological factors and not social factors as may be found in neurotic illnesses. He has appeared on national radio and television outlets and written for many newspapers. He has received two Commendation Medals by

344-755: A Peace Corps physician followed by practiced in the South Bronx , US. From 1970 to 1975, he was a special administrative assistant to the National Institute of Mental Health director. He then worked for a year in Alaska in the Indian Health Service. He became a ward physician at St. Elizabeths psychiatric hospital in Washington, D.C. for nine years, where he reportedly worked with the most challenging patients and aimed to avoid

516-665: A chateau on Castle Island , within present-day Albany; it was abandoned the following year due to flooding. In 1614, the Dutch, under the command of Hendrick Corstiaensen, rebuilt the French chateau, which they called Fort Nassau . Fort Nassau was the first Dutch settlement in North America, and was located along the Hudson River, also within present-day Albany. The small fort served as a trading post and warehouse. Located on

688-628: A humid subtropical climate . Weather in New York is heavily influenced by two continental air masses: a warm, humid one from the southwest and a cold, dry one from the northwest. Downstate New York (comprising New York City, Long Island, and lower portions of the Hudson Valley) have rather hot summers with some periods of high humidity and cold, damp winters which are relatively mild compared to temperatures in Upstate New York, due to

860-552: A belief that inhibits critical functioning and is widely considered delusional in one population may be common (and even adaptive) in another, or in the same population at a later time. Since normative views may contradict available evidence, a belief need not contravene cultural standards in order to be considered delusional. Prevalence in schizophrenia is generally considered at least 90%, and around 50% in bipolar disorder. The DSM-5 characterizes certain delusions as "bizarre" if they are clearly implausible, or are incompatible with

1032-446: A brain disorder. Historically, Karl Jaspers classified psychotic delusions into primary and secondary types. Primary delusions are defined as arising suddenly and not being comprehensible in terms of normal mental processes, whereas secondary delusions are typically understood as being influenced by the person's background or current situation (e.g., ethnicity; also religious, superstitious, or political beliefs). Disorganization

1204-482: A businessman who had made a fortune in direct-mail marketing and whose son had been diagnosed in the late 1980s with bipolar disorder, contacted Torrey and he and his wife provided the funds for the new institute. As of 2004 the Stanley Institute had 30 employees and funded half of all U.S. research on bipolar disorder and about a quarter of all schizophrenia research. In 2003 the institute's research budget

1376-533: A career most natives had turned to in hopes of trading with whites first. This completely changed the ethnography of the region, and most large game was hunted out before whites ever fully explored the land. Still, afterward, the Iroquois Confederacy offered shelter to refugees of the Mascouten , Erie, Chonnonton , Tutelo , Saponi , and Tuscarora nations. The Tuscarora became the sixth nation of

1548-431: A cenesthetic hallucination, is characterized by visceral sensations in the absence of stimuli. Cenesthetic hallucinations may include sensations of burning, or re-arrangement of internal organs. Psychosis may involve delusional beliefs. A delusion is a fixed, false idiosyncratic belief , which does not change even when presented with incontrovertible evidence to the contrary. Delusions are context- and culture-dependent:

1720-642: A cruel message of hope, or implicit blame, to those he believes cannot engage in a recovery process, despite being a laudable long-term vision for the commission. However, there is no current evidence that forcing psychiatric drug compliance reduces risk of crime. Furthermore, evidence suggests that using antipsychotic medication may not reduce risk of homicide, and use of other popular psychiatric drugs may increase risk (based on causal inference after controlling for confounding factors related to taking medication). Although Torrey described family members as "surviving schizophrenia" in his book of that title, in 1997 he said

1892-409: A deliberate and specific act by or message from some other entity), delusions of grandeur (the belief that one possesses special power or influence beyond one's actual limits), thought broadcasting (the belief that one's thoughts are audible) and thought insertion (the belief that one's thoughts are not one's own). A delusion may also involve misidentification of objects, persons, or environs that

SECTION 10

#1732793867044

2064-487: A failure of feedforward networks from sensory cortices to the inferior frontal cortex, which normally cancel out sensory cortex activity during internally generated speech. The resulting disruption in expected and perceived speech is thought to produce lucid hallucinatory experiences. The two-factor model of delusions posits that dysfunction in both belief formation systems and belief evaluation systems are necessary for delusions. Dysfunction in evaluations systems localized to

2236-749: A first-episode of psychosis and prediabetes. New York (state) New York , also called New York State , is a state in the Northeastern United States . One of the Mid-Atlantic states, it borders the Atlantic Ocean , New England , Canada, and the Great Lakes . With almost 19.6 million residents, it is the fourth-most populous state in the United States , and the 27th-largest state by area , with

2408-427: A flexible well-funded range of community mental health services , including Assertive Community Treatment , clubhouses (staffed by professionals with consumers as members), supported housing and supported employment , emphasizing illness and medication compliance throughout. However, he has criticized community alternatives which do not enforce drug treatment, such as those espoused by many psychiatric survivors and

2580-423: A global node of creativity and entrepreneurship , social tolerance , and environmental sustainability . The state attracts visitors from all over the globe, with the highest count of any U.S. state in 2022. Many of its landmarks are well known, including four of the world's ten most-visited tourist attractions in 2013: Times Square , Central Park , Niagara Falls , and Grand Central Terminal . New York

2752-488: A judge (at the urging of the person's psychiatrist and family members). Torrey has written several books on mental illness , including Surviving Schizophrenia . He is a distant relative of abolitionist Charles Turner Torrey and has written his biography. Torrey earned his bachelor's degree from Princeton University , and his M.D. from the McGill University Faculty of Medicine . Torrey also earned

2924-429: A large number of medications may provoke psychotic symptoms. Drugs that can induce psychosis experimentally or in a significant proportion of people include: The first brain image of an individual with psychosis was completed as far back as 1935 using a technique called pneumoencephalography (a painful and now obsolete procedure where cerebrospinal fluid is drained from around the brain and replaced with air to allow

3096-490: A long history of methamphetamine use and who have experienced psychosis in the past from methamphetamine use are highly likely to re-experience methamphetamine psychosis if drug use is recommenced. Methamphetamine-induced psychosis is likely gated by genetic vulnerability, which can produce long-term changes in brain neurochemistry following repetitive use. A 2024 study found that psychedelic use may potentially reduce, or have no effect on, psychotic symptoms in individuals with

3268-709: A major threat to the Abenaki and Mohicans, while the Susquehannock briefly conquered the Lenape in the 1600s. The most devastating event of the century, however, was the Beaver Wars . From approximately 1640–1680, the Iroquois peoples waged campaigns which extended from modern-day Michigan to Virginia against Algonquian and Siouan tribes, as well as each other. The aim was to control more land for animal trapping ,

3440-509: A master's degree in anthropology from Stanford University , and was trained in psychiatry at Stanford University School of Medicine. At McGill and later at Stanford, he was exposed to a biological approach and recalls that one of his first-year instructors at McGill was Heinz Lehmann , the first clinician in North America to use the first neuroleptic medication, chlorpromazine . Torrey practiced general medicine in Ethiopia for two years as

3612-440: A mechanism in psychosis. This theory is reinforced by the fact that dissociative NMDA receptor antagonists such as ketamine , PCP and dextromethorphan (at large overdoses) induce a psychotic state. The symptoms of dissociative intoxication are also considered to mirror the symptoms of schizophrenia, including negative symptoms . NMDA receptor antagonism, in addition to producing symptoms reminiscent of psychosis, mimics

SECTION 20

#1732793867044

3784-551: A moderate effect. Outcomes depend on the underlying cause. In the United States about 3% of people develop psychosis at some point in their lives. The condition has been described since at least the 4th century BC by Hippocrates and possibly as early as 1500 BC in the Egyptian Ebers Papyrus . A hallucination is defined as sensory perception in the absence of external stimuli. Hallucinations are different from illusions and perceptual distortions, which are

3956-717: A more prolonged period after use, or upon withdrawal . Individuals who experience substance-induced psychosis tend to have a greater awareness of their psychosis and tend to have higher levels of suicidal thinking compared to those who have a primary psychotic illness. Drugs commonly alleged to induce psychotic symptoms include alcohol , cannabis , cocaine , amphetamines , cathinones , psychedelic drugs (such as LSD and psilocybin ), κ-opioid receptor agonists (such as enadoline and salvinorin A ) and NMDA receptor antagonists (such as phencyclidine and ketamine ). Caffeine may worsen symptoms in those with schizophrenia and cause psychosis at very high doses in people without

4128-468: A person to do something potentially dangerous when combined with delusions. So-called "minor hallucinations", such as extracampine hallucinations, or false perceptions of people or movement occurring outside of one's visual field, frequently occur in neurocognitive disorders, such as Parkinson's disease. Visual hallucinations occur in roughly a third of people with schizophrenia, although rates as high as 55% are reported. The prevalence in bipolar disorder

4300-513: A personal or family history of psychotic disorders. A 2023 study found an interaction between lifetime psychedelic use and family history of psychosis or bipolar disorder on psychotic symptoms over the past two weeks. Psychotic symptoms were highest among individuals with both a family history of psychosis or bipolar disorder and lifetime psychedelic use, while they were lowest among those with lifetime psychedelic use but no family history of these disorders. Administration, or sometimes withdrawal, of

4472-459: A predictor of adolescent and adult psychosis. Individuals with psychotic symptoms are three times more likely to have experienced childhood trauma (e.g., physical or sexual abuse, physical or emotional neglect) than those in the general population. Increased individual vulnerability toward psychosis may interact with traumatic experiences promoting an onset of future psychotic symptoms, particularly during sensitive developmental periods. Importantly,

4644-707: A psychologist who died in 2018, was on both the NAMI and TAC boards. TAC has two other former NAMI board members on their board and Laurie Flynn, the former NAMI executive director, is part of the TAC Honorary Advisory Committee. In 2008, Torrey disagreed with a NAMI view on second-generation antipsychotics and accused the medical director and executive director of failing to disclose conflicts of interest, because they are employees of an organization that receives more than half its budget from pharmaceutical companies. He argued they were not representing

4816-425: A psychosis in 26–46 percent of heavy users. Some of these people develop a long-lasting psychosis that can persist for longer than six months. Those who have had a short-lived psychosis from methamphetamine can have a relapse of the methamphetamine psychosis years later after a stressful event such as severe insomnia or a period of hazardous alcohol use despite not relapsing back to methamphetamine. Individuals who have

4988-480: A region from the right STG to the right insula, left insula, and cerebellum, and are more severe in the right ACC, right STG, insula and cerebellum. Another meta analysis reported bilateral reductions in insula, operculum, STG, medial frontal cortex, and ACC, but also reported increased GMV in the right lingual gyrus and left precentral gyrus . The Kraepelinian dichotomy is made questionable by grey matter abnormalities in bipolar and schizophrenia; schizophrenia

5160-615: A research award from the International Congress of Schizophrenia. In 2005, a tribute to Torrey was included in NAMI's 25th Anniversary Celebratory Donor Wall. Torrey has criticized many organizations. He has charged the National Institute of Mental Health with not concentrating its resources sufficiently on severe mental illness and directly applicable research; NIMH has disputed his statistics and viewpoint. Experts such as Dr. Peter C. Gøtzsche , Dr. Jorun Rugkåsa, James Gottstein , and others have called into question both

5332-409: A response is thought to root from conferring excessive salience to otherwise mundane events. Dysfunction higher up in the hierarchy, where representation is more abstract, could result in delusions. The common finding of reduced GAD67 expression in psychotic disorders may explain enhanced AMPA mediated signaling, caused by reduced GABAergic inhibition. The connection between dopamine and psychosis

E. Fuller Torrey - Misplaced Pages Continue

5504-548: A result of the inability to feel motivation and drive towards both the desire to engage in as well as to complete tasks and goals. Previous research has indicated that a deficiency in the neural representation in regards to goals and the motivation to achieve them, has demonstrated that when a reward is not present, a strong reaction is noted in the ventral striatum; reinforcement learning is intact when contingencies about stimulus-reward are implicit, but not when they require explicit neural processing; reward prediction errors are what

5676-519: A symptom of chronic alcoholism that can appear in the acute withdrawal phase, shares many symptoms with alcohol-related psychosis suggesting a common mechanism. According to current studies, cannabis use is associated with increased risk of psychotic disorders, and the more often cannabis is used the more likely a person is to develop a psychotic illness. Furthermore, people with a history of cannabis use develop psychotic symptoms earlier than those who have never used cannabis. Some debate exists regarding

5848-659: A temperature of −13 °F (−25 °C) or lower can be expected in the northern highlands (Northern Plateau) and 5 °F (−15 °C) or colder in the southwestern and east-central highlands of the Southern Tier. New York had a record-high temperature of 108   °F (42.2   °C) on July 22, 1926, in the Albany area. Its record-lowest temperature during the winter was −52   °F (−46.7   °C) in 1979. Governors Island, Manhattan , in New York Harbor ,

6020-613: A total area of 54,555 square miles (141,297 km ) and ranks as the 27th-largest state by size . The highest elevation in New York is Mount Marcy in the Adirondack High Peaks in Northern New York , at 5,344 feet (1,629 meters) above sea level ; while the state's lowest point is at sea level, on the Atlantic Ocean in Downstate New York . In contrast with New York City's urban landscape,

6192-450: A total area of 54,556 square miles (141,300 km ). New York has a varied geography . The southeastern part of the state, known as Downstate , encompasses New York City , the United States's largest city; Long Island , the nation's most populous island; and the suburbs and wealthy enclaves of the lower Hudson Valley . These areas are the center of the expansive New York metropolitan area and account for approximately two-thirds of

6364-611: A water border with Rhode Island , while Connecticut has land and sea borders. Except for areas near the New York Harbor and the Upper Delaware River , New York has a mostly land border with two Mid-Atlantic states , New Jersey and Pennsylvania . New York is the only state that borders both the Great Lakes and the Atlantic Ocean . The Hudson River begins near Lake Tear of the Clouds and flows south through

6536-994: Is real and what is not real. Symptoms may include delusions and hallucinations , among other features. Additional symptoms are disorganized thinking and incoherent speech and behavior that is inappropriate for a given situation. There may also be sleep problems , social withdrawal , lack of motivation, and difficulties carrying out daily activities . Psychosis can have serious adverse outcomes. Psychosis can have several different causes. These include mental illness , such as schizophrenia or schizoaffective disorder , bipolar disorder , sensory deprivation , Wernicke–Korsakoff syndrome or cerebral beriberi and in rare cases major depression ( psychotic depression ). Other causes include: trauma , sleep deprivation , some medical conditions, certain medications , and drugs such as alcohol , cannabis , hallucinogens , and stimulants . One type, known as postpartum psychosis , can occur after giving birth. The neurotransmitter dopamine

6708-490: Is around 15%. Content commonly involves animate objects, although perceptual abnormalities such as changes in lighting, shading, streaks, or lines may be seen. Visual abnormalities may conflict with proprioceptive information, and visions may include experiences such as the ground tilting. Lilliputian hallucinations are less common in schizophrenia, and are more common in various types of encephalopathy , such as peduncular hallucinosis . A visceral hallucination, also called

6880-425: Is associated with ventral striatal (VS), which is the part of the brain that is involved with the desire to naturally satisfy the body's needs. When high reports of negative symptoms were recorded, there were significant irregularities in the left VS. Anhedonia, the inability to feel pleasure, is a commonly reported symptom in psychosis; experiences are present in most people with schizophrenia. Anhedonia arises as

7052-636: Is associated with negative symptoms; deficits in Dorsolateral Prefrontal Cortex (dlPFC) activity and failure to improve performance on cognitive tasks when offered monetary incentives are present; and dopamine mediated functions are abnormal. Psychosis has been traditionally linked to the overactivity of the neurotransmitter dopamine . In particular to its effect in the mesolimbic pathway . The two major sources of evidence given to support this theory are that dopamine receptor D2 blocking drugs (i.e., antipsychotics ) tend to reduce

E. Fuller Torrey - Misplaced Pages Continue

7224-413: Is associated with post-stroke delusions, and hypometabolism this region associated with caudate strokes presenting with delusions. The aberrant salience model suggests that delusions are a result of people assigning excessive importance to irrelevant stimuli. In support of this hypothesis, regions normally associated with the salience network demonstrate reduced grey matter in people with delusions, and

7396-554: Is believed to play an important role. Acute psychosis is termed primary if it results from a psychiatric condition and secondary if it is caused by another medical condition or drugs. The diagnosis of a mental-health condition requires excluding other potential causes. Testing may be done to check for central nervous system diseases, toxins, or other health problems as a cause. Treatment may include antipsychotic medication , psychotherapy , and social support . Early treatment appears to improve outcomes. Medications appear to have

7568-530: Is covered by ice. The summer climate is cool in the Adirondacks, Catskills, and at higher elevations of the Southern Tier. Buffalo and its metropolitan area are described as climate change havens for their weather pattern in Western New York. Summer daytime temperatures range from the high 70s to low 80s   °F (25 to 28   °C), over most of the state. In the majority of winter seasons,

7740-428: Is distinguishable from bipolar in that regions of grey matter reduction are generally larger in magnitude, although adjusting for gender differences reduces the difference to the left dorsomedial prefrontal cortex , and right dorsolateral prefrontal cortex . During attentional tasks, first episode psychosis is associated with hypoactivation in the right middle frontal gyrus, a region generally described as encompassing

7912-483: Is due to the long-term effects of alcohol consumption resulting in distortions to neuronal membranes, gene expression , as well as thiamine deficiency. It is possible that hazardous alcohol use via a kindling mechanism can cause the development of a chronic substance-induced psychotic disorder, i.e. schizophrenia. The effects of an alcohol-related psychosis include an increased risk of depression and suicide as well as causing psychosocial impairments. Delirium tremens ,

8084-612: Is generally believed to be complex. While dopamine receptor D2 suppresses adenylate cyclase activity, the D1 receptor increases it. If D2-blocking drugs are administered, the blocked dopamine spills over to the D1 receptors. The increased adenylate cyclase activity affects genetic expression in the nerve cell, which takes time. Hence antipsychotic drugs take a week or two to reduce the symptoms of psychosis. Moreover, newer and equally effective antipsychotic drugs actually block slightly less dopamine in

8256-514: Is home to approximately 200 colleges and universities , including Ivy League members Columbia University and Cornell University , and the expansive State University of New York , which is among the largest university systems in the nation. New York City is home to the headquarters of the United Nations , and it is sometimes described as the world's most important city, the cultural , financial , and media epicenter, and

8428-406: Is involved in five or six ongoing studies using anti-Toxoplasmosa gondii agents (e.g. antibiotics such as minocycline and azithromycin ) as an add-on treatment for schizophrenia. He believes that infectious causes will eventually explain the "vast majority" of schizophrenia cases. Some of his collaborators have disagreed with the emphasis he has placed on infection as a direct causal factor. Many of

8600-1028: Is not formally acknowledged by current ICD or DSM criteria. Its unclear place in psychiatric nosology has likely contributed to the limited scientific investigation and literature on the topic. Postpartum psychosis is a rare yet serious and debilitating form of psychosis. Symptoms range from fluctuating moods and insomnia to mood-incongruent delusions related to the individual or the infant. Women experiencing postpartum psychosis are at increased risk for suicide or infanticide. Many women who experience first-time psychosis from postpartum often have bipolar disorder, meaning they could experience an increase of psychotic episodes even after postpartum. A very large number of medical conditions can cause psychosis, sometimes called secondary psychosis . Examples include: Various psychoactive substances (both legal and illegal) have been implicated in causing, exacerbating, or precipitating psychotic states or disorders in users, with varying levels of evidence. This may be upon intoxication for

8772-493: Is placed in an empty room with no light and sound after 15 minutes, a phenomenon known as sensory deprivation . Neuroticism , a personality trait associated with vulnerability to stressors, is an independent predictor of the development of psychosis. From a diagnostic standpoint, organic disorders were believed to be caused by physical illness affecting the brain (that is, psychiatric disorders secondary to other conditions) while functional disorders were considered disorders of

SECTION 50

#1732793867044

8944-536: Is planned to host a US$ 1 billion research and education center poised to make New York the global leader in addressing the climate crisis . Due to New York's relatively large land area and unique geography compared to other eastern states, there are several distinct ecoregions present in the state, many of them reduced heavily due to urbanization and other human activities: Southern Great Lakes forests in Western New York , New England–Acadian forests on

9116-687: Is psychosis or autism spectrum disorder, social or generalized anxiety disorder, or obsessive-compulsive disorder. The symptoms of psychosis may be caused by serious psychiatric disorders such as schizophrenia , a number of medical illnesses, and trauma . Psychosis may also be temporary or transient, and be caused by medications or substance use disorder ( substance-induced psychosis ). Brief hallucinations are not uncommon in those without any psychiatric disease, including healthy children. Causes or triggers include: Traumatic life events have been linked with an elevated risk of developing psychotic symptoms. Childhood trauma has specifically been shown to be

9288-453: Is reported in posterior insula, ventral medial frontal cortex, and ventral ACC. Studies during acute experiences of hallucinations demonstrate increased activity in primary or secondary sensory cortices. As auditory hallucinations are most common in psychosis, most robust evidence exists for increased activity in the left middle temporal gyrus , left superior temporal gyrus , and left inferior frontal gyrus (i.e. Broca's area ). Activity in

9460-658: Is shared between New York and Ontario as it flows on the Niagara River from Lake Erie to Lake Ontario. The Delaware River Basin Compact, signed in 1961 by New York, New Jersey, Pennsylvania , Delaware , and the federal government, regulates the utilization of water of the Delaware system. Under the Köppen climate classification , most of New York has a humid continental climate , though New York City and Long Island have

9632-624: Is split into disorganized speech (or thought), and grossly disorganized motor behavior. Disorganized speech or thought, also called formal thought disorder , is disorganization of thinking that is inferred from speech. Characteristics of disorganized speech include rapidly switching topics, called derailment or loose association; switching to topics that are unrelated, called tangential thinking; incomprehensible speech, called word salad or incoherence. Disorganized motor behavior includes repetitive, odd, or sometimes purposeless movement. Disorganized motor behavior rarely includes catatonia, and although it

9804-527: Is true for New York City: four of its five boroughs are situated on three islands at the mouth of the Hudson River : Manhattan Island ; Staten Island ; and Long Island , which contains Brooklyn and Queens at its western end. The state's borders include a water boundary in (clockwise from the west) two Great Lakes ( Lake Erie and Lake Ontario , which are connected by the Niagara River );

9976-877: The Abenaki and the Schaghticoke . Many of the Mohicans remained in the region until the 1800s, however, a small group known as the Ouabano migrated southwest into West Virginia at an earlier time. They may have merged with the Shawnee . The Mohawk and Susquehannock were the most militaristic . Trying to corner trade with the Europeans, they targeted other tribes. The Mohawk were also known for refusing white settlement on their land and discriminating against any of their people who converted to Christianity . They posed

10148-531: The American Civil War , in terms of finances, volunteer soldiers, and supplies. The state provided more than 370,000 soldiers to the Union armies. Over 53,000 New Yorkers died in service, roughly one of every seven who served. However, Irish draft riots in 1862 were a significant embarrassment. Since the early 19th century, New York City has been the largest port of entry for legal immigration into

10320-651: The Capital Region entered Phase   1 of reopening. On May 26, the Hudson Valley began Phase   1, and New York City partially reopened on June 8. During July 2020, a federal judge ruled Governor Andrew Cuomo and Mayor Bill de Blasio exceeded authority by limiting religious gatherings to 25% when others operated at 50% capacity. On Thanksgiving Eve, the U.S. Supreme Court blocked additional religious restrictions imposed by Cuomo for areas with high infection rates. The state of New York covers

10492-620: The Continental Army at the Battle of Saratoga in 1777, a success that influenced France to ally with the revolutionaries; the state constitution was enacted in 1777. New York became the 11th state to ratify the United States Constitution , on July 26, 1788. In an attempt to retain their sovereignty and remain an independent nation positioned between the new United States and British North America , four of

SECTION 60

#1732793867044

10664-465: The Declaration of Independence on July 9, 1776. The New York State Constitution was framed by a convention which assembled at White Plains on July 10, 1776, and after repeated adjournments and changes of location, finished its work at Kingston on Sunday evening, April 20, 1777, when the new constitution drafted by John Jay was adopted with but one dissenting vote. It was not submitted to

10836-681: The Great Lakes , with the port of New York City. Improving transportation, it enabled additional population migration to territories west of New York. After 1850, railroads largely replaced the canal. The connectivity offered by the canal, and subsequently the railroads, led to an economic boom across the entire state through the 1950s. Major corporations that got their start in New York during this time include American Express , AT&T , Bristol Myers Squibb , Carrier , Chase , General Electric , Goldman Sachs , IBM , Kodak , Macy's , NBC , Pfizer , Random House , RCA , Tiffany & Co. , Wells Fargo , Western Union , and Xerox . New York City

11008-777: The Iroquois Nations fought on the side of the British; only the Oneida and their dependents, the Tuscarora, allied themselves with the Americans. In retaliation for attacks on the frontier led by Joseph Brant and Loyalist Mohawk forces , the Sullivan Expedition of 1779 destroyed nearly 50 Iroquois villages, adjacent croplands and winter stores, forcing many refugees to British-held Niagara. As allies of

11180-744: The Lake Champlain Valley . The Great Appalachian Valley dominates eastern New York and contains Lake Champlain Valley as its northern half and the Hudson Valley as its southern half within the state. The Tug Hill region arises as a cuesta east of Lake Ontario . The state of New York contains a part of the Marcellus shale , which extends into Ohio and Pennsylvania. Upstate and Downstate are often used informally to distinguish New York City or its greater metropolitan area from

11352-770: The Mohawk —part of the original Iroquois Five Nations, and the Petun . South of them, divided roughly along Appalachia , were the Susquehannock and the Erie . Many of the Wampanoag and Mohican peoples were caught up in King Philip's War , a joint effort of many New England tribes to push Europeans off their land. After the death of their leader, Chief Philip Metacomet , most of those peoples fled inland, splitting into

11524-589: The National Empowerment Center . Torrey has appeared on national radio and television (outlets like NPR, Oprah, 20/20, 60 Minutes, and Dateline) and has written for many newspapers. He has received a 1984 Special Families Award from NAMI, two Commendation Medals from the U.S. Public Health Service , a 1991 National Caring Award, and a humanitarian award from NARSAD (now known as the Brain & Behavior Research Foundation ). In 1999, he received

11696-534: The New England border, Northeastern coastal forests in the lower Hudson Valley and western Long Island , Atlantic coastal pine barrens in southern Long Island, Northeastern interior dry–mesic oak forest in the eastern Southern Tier and upper Hudson Valley, Appalachian–Blue Ridge forests in the Hudson Valley), Central Appalachian dry oak–pine forest around the Hudson Valley, Eastern Great Lakes and Hudson Lowlands , Eastern forest–boreal transition in

11868-654: The New York State Legislature created the Board of Commissioners of Immigration to regulate immigration. The first permanent immigration depot in New York was established in 1855 at Castle Garden , a converted War of 1812 era fort located within what is now Battery Park , at the tip of Lower Manhattan. The first immigrants to arrive at the new depot were aboard three ships that had just been released from quarantine . Castle Garden served as New York's immigrant depot until it closed on April 18, 1890, when

12040-641: The Philadelphia Convention , which drafted the United States Constitution, in which he also took part. The new government was to be a strong federal national government to replace the relatively weaker confederation of individual states. Following heated debate, which included the publication of The Federalist Papers as a series of installments in New York City newspapers, New York was the 11th state to ratify

12212-606: The United States Constitution , on July 26, 1788. New York City remained the national capital under the new constitution until 1790 when it was moved to Philadelphia until 1800, when it was relocated to its current location in Washington, D.C. and was the site of the inauguration of President George Washington, In the first session of the Supreme Court of the United States , the United States Bill of Rights were drafted. Transportation in Western New York

12384-539: The World Trade Center site . On October 29 and 30, 2012, Hurricane Sandy caused extensive destruction of the state's shorelines, ravaging portions of New York City, Long Island , and southern Westchester with record-high storm surge , with severe flooding and high winds causing power outages for hundreds of thousands of New Yorkers, and leading to gasoline shortages and disruption of mass transit systems. The storm and its profound effects have prompted

12556-473: The inability to feel pleasure ( anhedonia ). Altered Behavioral Inhibition System functioning could possibly cause reduced sustained attention in psychosis and overall contribute to more negative reactions. Psychosis is rare in adolescents. Young people who have psychosis may have trouble connecting with the world around them and may experience hallucinations or delusions. Adolescents with psychosis may also have cognitive deficits that may make it harder for

12728-517: The ring-necked pheasant , northern bobwhite , ruffed grouse , spruce grouse , Canada jay , wild turkey , blue jay , eastern bluebird (the state bird ), American robin , and black-capped chickadee . Birds of prey that are present in the state are great horned owls , bald eagles , red-tailed hawks , American kestrels , and northern harriers . Waterfowl like mallards , wood ducks , canvasbacks , American black ducks , trumpeter swans , Canada geese , and blue-winged teals can be found in

12900-422: The ventral striatum , hippocampus , and ACC are related to the lucidity of hallucinations, and indicate that activation or involvement of emotional circuitry are key to the impact of abnormal activity in sensory cortices. Together, these findings indicate abnormal processing of internally generated sensory experiences, coupled with abnormal emotional processing, results in hallucinations. One proposed model involves

13072-539: The white-footed mouse , North American least shrew , little brown bat , muskrat , eastern gray squirrel , eastern cottontail , American ermine , groundhog , striped skunk , fisher , North American river otter , raccoon , bobcat , eastern coyote , red fox , gray fox white-tailed deer , moose , and American black bear ; extirpated mammals include Canada lynx , American bison , wolverine , Allegheny woodrat , caribou , eastern elk , eastern cougar , and eastern wolf . Some species of birds in New York are

13244-548: The Adirondacks, Eastern Great Lakes lowland forests around the Adirondacks, and Allegheny Highlands forests , most of which are in the western Southern Tier. Some species that can be found in this state are American ginseng , starry stonewort , waterthyme , water chestnut, eastern poison ivy , poison sumac , giant hogweed , cow parsnip and common nettle . There are more than 70 mammal species, more than 20 bird species, some species of amphibians, and several reptile species. Species of mammals that are found in New York are

13416-543: The British, the Iroquois were forced out of New York, although they had not been part of treaty negotiations. They resettled in Canada after the war and were given land grants by the Crown. In the treaty settlement, the British ceded most Indian lands to the new United States. Because New York made a treaty with the Iroquois without getting Congressional approval, some of the land purchases have been subject to land claim suits since

13588-564: The CMHS. Torrey has in general been instrumental in lobbying against, and undermining, community-based consumer projects because they promoted social and experiential recovery and questioned the standard medical model. Consumer organizations have protested that they are already economically disadvantaged and vulnerable to political whim while Torrey and his organizations have rich and powerful backers. It has been argued that Torrey and other psychiatric and family member advocates do not necessarily have

13760-610: The Hudson River flood plain, the rudimentary fort was washed away by flooding in 1617, and abandoned for good after Fort Orange (New Netherland) was built nearby in 1623. Henry Hudson's 1609 voyage marked the beginning of European involvement in the area. Sailing for the Dutch East India Company and looking for a passage to Asia, he entered the Upper New York Bay on September 11 of that year. Word of his findings encouraged Dutch merchants to explore

13932-602: The Iroquois Confederacy include the Seneca, Cayuga, Onondaga, Oneida, Tuscarora and Mohawk. The Iroquois fought for both sides during the Revolutionary War ; afterwards many pro-British Iroquois migrated to Canada. Today, the Iroquois still live in several enclaves across New York and Ontario. Meanwhile, the Lenape formed a close relationship with William Penn . However, upon Penn's death, his sons managed to take over much of their lands and banish them to Ohio. When

14104-596: The Iroquois. In the 1700s, Iroquoian peoples would take in the remaining Susquehannock of Pennsylvania after they were decimated in the French and Indian War . Most of these other groups assimilated and eventually ceased to exist as separate tribes. Then, after the American Revolution , a large group of Seneca split off and returned to Ohio, becoming known as the Mingo Seneca. The current Six Nations of

14276-557: The King of France's sister . Verrazzano described it as "a vast coastline with a deep delta in which every kind of ship could pass" and he adds: "that it extends inland for a league and opens up to form a beautiful lake. This vast sheet of water swarmed with native boats." He landed on the tip of Manhattan and possibly on the furthest point of Long Island. Verrazzano's stay was interrupted by a storm which pushed him north towards Martha's Vineyard . In 1540, French traders from New France built

14448-589: The Lenape. In 1524, Giovanni da Verrazzano , an Italian explorer in the service of the French crown , explored the Atlantic coast of North America between the Carolinas and Newfoundland , including New York Harbor and Narragansett Bay . On April 17, 1524, Verrazzano entered New York Bay , by way of the strait now called the Narrows into the northern bay which he named Santa Margherita, in honor of

14620-594: The Twin Towers of the original World Trade Center in Lower Manhattan , and the towers collapsed . 7 World Trade Center also collapsed due to damage from fires. The other buildings of the World Trade Center complex were damaged beyond repair and demolished soon thereafter. The collapse of the Twin Towers caused extensive damage and resulted in the deaths of 2,753 victims, including 147 aboard

14792-559: The U.S. Public Health Service along with other awards and tributes. He has been criticized by a range of people, including federal researchers and others for some of his attacks on de-institutionalization and his support for forced medication as a method of treatment. Torrey is on the board of the Treatment Advocacy Center (TAC), which describes itself as being "a national nonprofit advocacy organization". TAC supports involuntary treatment when deemed appropriate by

14964-624: The U.S. drafted the Indian Removal Act , the Lenape were further moved to Missouri, whereas their cousins, the Mohicans, were sent to Wisconsin. Also, in 1778, the United States relocated the Nanticoke from the Delmarva Peninsula to the former Iroquois lands south of Lake Ontario, though they did not stay long. Mostly, they chose to migrate into Canada and merge with the Iroquois, although some moved west and merged with

15136-471: The United States . In the United States, the federal government did not assume direct jurisdiction for immigration until 1890. Prior to this time, the matter was delegated to the individual states, then via contract between the states and the federal government. Most immigrants to New York would disembark at the bustling docks along the Hudson and East Rivers , in the eventual Lower Manhattan . On May 4, 1847,

15308-460: The United States can trace their ancestry to these immigrants. Ellis Island was the subject of a contentious and long-running border and jurisdictional dispute between the State of New York and the State of New Jersey, as both claimed it. The issue was officially settled in 1998 by the U.S. Supreme Court which ruled that the original 3.3-acre (1.3 ha) island was New York state territory and that

15480-591: The actual reward is versus what the reward was predicted to be. In most cases positive prediction errors are considered an abnormal occurrence. A positive prediction error response occurs when there is an increased activation in a brain region, typically the striatum , in response to unexpected rewards. A negative prediction error response occurs when there is a decreased activation in a region when predicted rewards do not occur. Anterior Cingulate Cortex (ACC) response, taken as an indicator of effort allocation, does not increase with reward or reward probability increase, and

15652-449: The afflicted should reasonably be able to recognize; such examples include Cotard's syndrome (the belief that oneself is partly or wholly dead ) and clinical lycanthropy (the belief that oneself is or has transformed into an animal). The subject matter of delusions seems to reflect the current culture in a particular time and location. For example, in the US, during the early 1900s syphilis

15824-618: The balance of the 27.5 acres (11 ha) added after 1834 by landfill was in New Jersey. In May 1964, Ellis Island was added to the National Park Service by President Lyndon B. Johnson and is still owned by the federal government as part of the Statue of Liberty National Monument . In 1990, Ellis Island was opened to the public as a museum of immigration. On September 11, 2001, two of four hijacked planes were flown into

15996-512: The brain than older drugs whilst also blocking 5-HT2A receptors, suggesting the 'dopamine hypothesis' may be oversimplified. Soyka and colleagues found no evidence of dopaminergic dysfunction in people with alcohol-induced psychosis and Zoldan et al. reported moderately successful use of ondansetron , a 5-HT 3 receptor antagonist, in the treatment of levodopa psychosis in Parkinson's disease patients. A review found an association between

16168-512: The canal carrying passengers and freight. Farm products came in from the Midwest , and finished manufactured goods moved west. It was an engineering marvel which opened up vast areas of New York to commerce and settlement. It enabled Great Lakes port cities such as Buffalo and Rochester to grow and prosper. It also connected the burgeoning agricultural production of the Midwest and shipping on

16340-574: The capital of the world. The Native American tribes in what is now New York were predominantly Iroquois and Algonquian . Long Island was divided roughly in half between the Algonquian Wampanoag and Lenape peoples. The Lenape also controlled most of the region surrounding New York Harbor . North of the Lenape was a third Algonquian nation, the Mohicans . Starting north of them, from east to west, were two Iroquoian nations:

16512-690: The causal relationship between cannabis use and psychosis with some studies suggesting that cannabis use hastens the onset of psychosis primarily in those with pre-existing vulnerability. Indeed, cannabis use plays an important role in the development of psychosis in vulnerable individuals, and cannabis use in adolescence should be discouraged. Some studies indicate that the effects of two active compounds in cannabis, tetrahydrocannabinol (THC) and cannabidiol (CBD), have opposite effects with respect to psychosis. While THC can induce psychotic symptoms in healthy individuals, limited evidence suggests that CBD may have antipsychotic effects. Methamphetamine induces

16684-629: The cities of Buffalo and Rochester , is part of the Great Lakes region and borders Lake Ontario and Lake Erie . Central New York is anchored by the city of Syracuse ; between the central and western parts of the state, New York is dominated by the Finger Lakes , a popular tourist destination. To the south, along the state border with Pennsylvania , the Southern Tier sits atop the Allegheny Plateau , representing some of

16856-649: The city on October 19 of that year, composed of representatives from across the Thirteen Colonies who set the stage for the Continental Congress to follow. The Stamp Act Congress resulted in the Declaration of Rights and Grievances , which was the first written expression by representatives of the Americans of many of the rights and complaints later expressed in the United States Declaration of Independence . This included

17028-578: The coast in search of profitable fur trading with local Native American tribes. During the 17th century, Dutch trading posts established for the trade of pelts from the Lenape, Iroquois, and other tribes were founded in the colony of New Netherland . The first of these trading posts were Fort Nassau (1614, near present-day Albany ); Fort Orange (1624, on the Hudson River just south of the current city of Albany and created to replace Fort Nassau), developing into settlement Beverwijck (1647), and into what became Albany; Fort Amsterdam (1625, to develop into

17200-458: The community without supervision. TAC has been credited by New York State Attorney General Eliot Spitzer and others with helping pass Kendra's Law in the state. Kendra's Law allows court-ordered involuntary treatment of people diagnosed with schizophrenia or other severe mental illness who have a history of not following psychiatric advice, i.e., individuals who are, "as a result of his or her mental illness, unlikely to voluntarily participate in

17372-441: The condition. Cannabis and other illicit recreational drugs are often associated with psychosis in adolescents and cannabis use before 15 years old may increase the risk of psychosis in adulthood. Approximately three percent of people with alcoholism experience psychosis during acute intoxication or withdrawal. Alcohol related psychosis may manifest itself through a kindling mechanism . The mechanism of alcohol-related psychosis

17544-476: The construction of the Erie Canal , gave it incomparable advantages over other regions of the United States. The state built its political, cultural, and economic ascendancy over the next century, earning it the nickname of the " Empire State ". Although deindustrialization eroded a portion of the state's economy in the second half of the 20th century, New York in the 21st century continues to be considered as

17716-433: The director and members of MindFreedom International of living off federal funds while denying illness and not caring about the mentally ill on the streets and in prisons. Torrey has been a vocal critic of the failures of deinstitutionalization and inadequate community mental health services . He has generally linked this to issues of violence, homelessness and medication noncompliance, as well as lack of proper focus by

17888-427: The discussion of constructing seawalls and other coastal barriers around the shorelines of New York City and Long Island to minimize the risk from another such future event. Such risk is considered highly probable due to global warming and rising sea levels . On March 1, 2020, New York had its first confirmed case of COVID-19 after Washington (state) , two months prior. From May 19–20, Western New York and

18060-411: The dorsolateral prefrontal cortex (dlPFC).Altered Behavioral Inhibition System functioning could possibly cause reduced sustained attention in psychosis and overall contribute to more negative reactions. In congruence with studies on grey matter volume, hypoactivity in the right insula, and right inferior parietal lobe is also reported. During cognitive tasks, hypoactivities in the right insula, dACC, and

18232-545: The downstate region's lower elevation, proximity to the Atlantic Ocean, and relatively lower latitude . Upstate New York experiences warm summers, marred by only occasional, brief intervals of sultry conditions, with long and cold winters. Western New York, particularly the Tug Hill region, receives heavy lake-effect snows , especially during the earlier portions of winter, before the surface of Lake Ontario itself

18404-402: The duration of the conflict, and consequently the focus of General George Washington 's intelligence network . On the notorious British prison ships of Wallabout Bay , more American combatants died than were killed in combat in every battle of the war combined. Both sides of combatants lost more soldiers to disease than to outright wounds. The first of two major British armies were captured by

18576-556: The early 1970s, Torrey became interested in viral infections as possible causes of schizophrenia or bipolar disorder, particularly a parasite Toxoplasma gondii whose definitive host is the cat , but whose intermediate host can be any mammal, including humans. Up to one third of the world's human population is estimated to carry a Toxoplasma infection. Since then he has published, often with Robert Yolken, more than 30 articles on seasonal variation and possible infectious causes of schizophrenia, focusing especially on Toxoplasma gondii. He

18748-671: The eastern part of the state, without draining Lakes George or Champlain . Lake George empties at its north end into Lake Champlain, whose northern end extends into Canada, where it drains into the Richelieu River and then ultimately the Saint Lawrence River . The western section of the state is drained by the Allegheny River and rivers of the Susquehanna and Delaware River systems. Niagara Falls

18920-532: The evidence basis and ethics of coercive practices such as court-ordered treatment, citing substantial scientific literature and patient testimony showing harm and/or lack of benefit. The United Nations and its World Health Organization have repeatedly called for the end to coercive interventions in psychiatry, naming them as human rights violations traumatizing significant portions of those affected; instead, they suggest community-based alternatives without threat of force. Torrey has been charged with acting to limit

19092-523: The fact that psychosis commonly occurs in neurodegenerative diseases of the dopaminergic nervous system, such as Parkinson's disease, which involved reduced, rather than increased, dopaminergic activity. The endocannabinoid system is also implicated in psychosis. This is evidenced by the propensity of CB 1 receptor agonists such as THC to induce psychotic symptoms, and the efficacy of CB 1 receptor antagonists such as CBD in ameliorating psychosis. NMDA receptor dysfunction has been proposed as

19264-565: The federal government assumed control over immigration. During that period, more than eight million immigrants passed through its doors (two of every three U.S. immigrants). When the federal government assumed control, it established the Bureau of Immigration , which chose the three-acre (1.2 ha) Ellis Island in Upper New York Harbor for an entry depot. Already federally controlled, the island had served as an ammunition depot. It

19436-449: The following: Psychotic symptoms may also be seen in: Subtypes of psychosis include: Cycloid psychosis is typically an acute, self-limiting form of psychosis with psychotic and mood symptoms that progress from normal to full-blown, usually between a few hours to days, and not related to drug intake or brain injury . While proposed as a distinct entity, clinically separate from schizophrenia and affective disorders, cycloid psychosis

19608-482: The functioning of the mind in the absence of physical disorders (that is, primary psychological or psychiatric disorders). Subtle physical abnormalities have been found in illnesses traditionally considered functional, such as schizophrenia . The DSM-IV-TR avoids the functional/organic distinction, and instead lists traditional psychotic illnesses, psychosis due to general medical conditions, and substance-induced psychosis. Primary psychiatric causes of psychosis include

19780-407: The intensity of psychotic symptoms, and that drugs that accentuate dopamine release, or inhibit its reuptake (such as amphetamines and cocaine ) can trigger psychosis in some people (see stimulant psychosis ). However, there is substantial evidence that dopaminergic overactivity does not fully explain psychosis, and that neurodegerative pathophysiology plays a significant role. This is evidenced by

19952-584: The journal. Others, while agreeing that public mental health care in the U.S. falls far short of what people with serious psychiatric disorders need and deserve, have argued that Torrey's solutions are outdated and that his book The Insanity Offense is based on unsubstantiated portrayals of certainty on the statistics on violence, outpatient commitment and medication, stigmatizing tens of thousands of people, deeply offending and insulting those who hold views differing from his own, and promulgating one-dimensional solutions. TAC's attempts to associate violent incidents in

20124-594: The late 20th century by the federally recognized tribes. New York put up more than 5 million acres (20,000 km ) of former Iroquois territory for sale in the years after the Revolutionary War, leading to rapid development in Upstate New York. As per the Treaty of Paris , the last vestige of British authority in the former Thirteen Colonies —their troops in New York City—departed in 1783, which

20296-494: The left precuneus, as well as reduced deactivations in the right basal ganglia , right thalamus , right inferior frontal and left precentral gyri are observed. These results are highly consistent and replicable possibly except the abnormalities of the right inferior frontal gyrus. Decreased grey matter volume in conjunction with bilateral hypoactivity is observed in anterior insula, dorsal medial frontal cortex, and dorsal ACC. Decreased grey matter volume and bilateral hyperactivity

20468-422: The medical establishment had previously held that parenting was responsible for schizophrenia. Torrey helped build NAMI into a powerful political force through campaigning and donating the hardcover royalties from the sale of his book Surviving Schizophrenia . Although Torrey, TAC, and NAMI remain aligned, NAMI may have tried to distance itself from TAC in 1998. One source The Psychiatric Times , reported that TAC

20640-501: The misperception of external stimuli. Hallucinations may occur in any of the senses and take on almost any form. They may consist of simple sensations (such as lights, colors, sounds, tastes, or smells) or more detailed experiences (such as seeing and interacting with animals and people, hearing voices , and having complex tactile sensations). Hallucinations are generally characterized as being vivid and uncontrollable. Auditory hallucinations , particularly experiences of hearing voices, are

20812-496: The most common and often prominent feature of psychosis. Up to 15% of the general population may experience auditory hallucinations (though not all are due to psychosis). The prevalence of auditory hallucinations in patients with schizophrenia is generally put around 70%, but may go as high as 98%. Reported prevalence in bipolar disorder ranges between 11% and 68%. During the early 20th century, auditory hallucinations were second to visual hallucinations in frequency, but they are now

20984-613: The most common manifestation of schizophrenia, although rates vary between cultures and regions. Auditory hallucinations are most commonly intelligible voices. When voices are present, the average number has been estimated at three. Content, like frequency, differs significantly, especially across cultures and demographics. People who experience auditory hallucinations can frequently identify the loudness, location of origin, and may settle on identities for voices. Western cultures are associated with auditory experiences concerning religious content, frequently related to sin. Hallucinations may command

21156-549: The multiethnic colony of New Netherland in 1621. England seized the colony from the Dutch in 1664, renaming it the Province of New York . During the American Revolutionary War , a group of colonists eventually succeeded in establishing independence, and the state ratified the then new United States Constitution in 1788. From the early 19th century, New York's development of its interior, beginning with

21328-529: The neurophysiological aspects, such as reduction in the amplitude of P50 , P300 , and MMN evoked potentials . Hierarchical Bayesian neurocomputational models of sensory feedback, in agreement with neuroimaging literature, link NMDA receptor hypofunction to delusional or hallucinatory symptoms via proposing a failure of NMDA mediated top down predictions to adequately cancel out enhanced bottom up AMPA mediated predictions errors. Excessive prediction errors in response to stimuli that would normally not produce such

21500-626: The neurotransmitter dopamine , which is widely implicated in salience processing, is also widely implicated in psychotic disorders. Specific regions have been associated with specific types of delusions. The volume of the hippocampus and parahippocampus is related to paranoid delusions in Alzheimer's disease , and has been reported to be abnormal post mortem in one person with delusions. Capgras delusions have been associated with occipito-temporal damage, and may be related to failure to elicit normal emotions or memories in response to faces. Psychosis

21672-515: The news with lack of medication have been described as wild hyperbole , and the use of the term "assisted treatment" has been described as a euphemism for forced drugging. Torrey has been criticized by, and has criticized, Thomas Szasz , a libertarian psychiatrist and author of The Myth of Mental Illness (1961), who is opposed to involuntary treatment. Torrey has said he admires Szasz for his outspoken criticisms of many psychiatric practices, including "diagnostic creep" ( disease mongering ) and

21844-621: The northernmost reaches of Appalachia . New York was one of the original Thirteen Colonies that went on to form the United States. The area of present-day New York had been inhabited by tribes of the Algonquians and the Iroquois Confederacy Native Americans for several thousand years by the time the earliest Europeans arrived. Stemming from Henry Hudson 's expedition in 1609, the Dutch established

22016-619: The people for ratification. On July 30, 1777, George Clinton was inaugurated as the first Governor of New York at Kingston. Approximately a third of the battles of the American Revolutionary War took place in New York; the first major one and largest of the entire war was the Battle of Long Island , also known as the Battle of Brooklyn, in August 1776. After their victory, the British occupied present-day New York City, making it their military and political base of operations in North America for

22188-427: The potential for the political abuse of psychiatric labels, but he has criticized Szasz for asserting that schizophrenia is not an organic disease of the brain like, for example, Parkinson's disease or multiple sclerosis . Torrey has authored 21 books and more than 200 lay and professional papers. Psychosis Psychosis is a condition of the mind or psyche that results in difficulties determining what

22360-417: The profoundly agitated state described above. It involves excessive and purposeless motor behaviour, as well as an extreme mental preoccupation that prevents an intact experience of reality. An example is someone walking very fast in circles to the exclusion of anything else with a level of mental preoccupation (meaning not focused on anything relevant to the situation) that was not typical of the person prior to

22532-614: The provinces of Ontario and Quebec in Canada, with New York and Ontario sharing the Thousand Islands archipelago within the Saint Lawrence River, while most of its border with Quebec is on land; it shares Lake Champlain with the New England state of Vermont ; the New England state of Massachusetts has mostly a land border; New York extends into Long Island Sound and the Atlantic Ocean , sharing

22704-633: The recommended treatment pursuant to the treatment plan." Previously, only inpatient programs were available to submit a person to involuntary treatment. TAC's efforts to pass Kendra's Law led to similar successful passage of Laura's Law in California , and similar laws in Florida and elsewhere. Torrey was for many years an active advisor for the National Alliance on Mental Illness (NAMI). Parents felt that he spoke up for them when much of

22876-400: The region. Maritime or shore birds of New York are great blue heron , killdeers , northern cardinals , American herring gulls , and common terns . Reptile and amphibian species in land areas of New York include queen snakes , hellbenders , diamondback terrapins , timber rattlesnakes , eastern fence lizards , spotted turtles , and Blanding's turtles . Sea turtles that can be found in

23048-471: The relationship between traumatic life events and psychotic symptoms appears to be dose-dependent in which multiple traumatic life events accumulate, compounding symptom expression and severity. However, acute, stressful events can also trigger brief psychotic episodes. Trauma prevention and early intervention may be an important target for decreasing the incidence of psychotic disorders and ameliorating its effects. A healthy person could become psychotic if he

23220-405: The relevant governmental organizations. He has been accused of gaining influence by sensationalizing and exaggerating the incidence of violence and its link to medication noncompliance, including disseminating unsubstantiated and unreliable statistics. When a California NAMI journal editor included a questioning of Torrey's statistics, the local board glued together the pages and effectively shut down

23392-733: The research studies on links between schizophrenia and Toxoplasma gondii , by different authors in different countries, are funded and supported by the Stanley Medical Research Institute. The hypothesis is not prominent in current mainstream scientific views on the causes of schizophrenia , although infections may be seen as one possible risk factor that could lead to vulnerabilities in early neurodevelopment in some cases. Torrey hopes to live long enough to see vaccines to prevent many or most cases of schizophrenia. Torrey has generally been in favor of antipsychotic drugs. He has claimed that taking antipsychotics reduces

23564-605: The rest of the State of New York. The placement of a boundary between the two is a matter of great contention. Unofficial and loosely defined regions of Upstate New York include from the Southern Tier, which includes many of the counties along the border with Pennsylvania, to the North Country region, above or sometimes including parts of the Adirondack region. Among the total area of New York state, 13.6% consists of water. Much of New York's boundaries are in water, as

23736-477: The right lateral prefrontal cortex, regardless of delusion content, is supported by neuroimaging studies and is congruent with its role in conflict monitoring in healthy persons. Abnormal activation and reduced volume is seen in people with delusions, as well as in disorders associated with delusions such as frontotemporal dementia , psychosis and Lewy body dementia . Furthermore, lesions to this region are associated with "jumping to conclusions", damage to this region

23908-452: The right to representative government . At the same time, given strong commercial, personal and sentimental links to Britain , many New York residents were Loyalists . The Capture of Fort Ticonderoga provided the cannon and gunpowder necessary to force a British withdrawal from the siege of Boston in 1775. New York was the only colony not to vote for independence , as the delegates were not authorized to do so. New York then endorsed

24080-731: The risk of violence, homelessness and prison. He has argued that "noncompliance" in about half of cases of schizophrenia and bipolar disorder is due to lack of "insight" into the illness because the part of the brain for self-awareness has been affected; and that in some who are aware it is due to adverse effects ranging from tremors or sedation to sexual dysfunction to substantial weight gain. He has also reported that at least some antipsychotics cause medical conditions that can be fatal in some people, especially African Americans . He has also argued that pharmaceutical companies have too much influence over psychiatric organizations and psychiatrists, effectively buying them off. Torrey has advocated in favor of

24252-500: The same interests as consumers/survivors themselves. Differences in ideology sharpened after the development of NAMI. In criticizing the New Freedom Commission on Mental Health for not recommending forced outpatient medicating, Torrey claimed that stigma against people with mental disorders was largely due to them committing violent acts due to not taking medication. He called the recovery model harmful for sending

24424-494: The same journal in 1999, Torrey and Miller of the Stanley Foundation Research Program argued for an incentivised schizophrenia treatment system backed by a credible threat of force, modeled on that used for the fatal infectious disease tuberculosis ; replies criticized the logic of the analogy and resort to forced drugging rather than developing alliances and understanding, to which Torrey accused

24596-469: The seriously mentally ill due to a hippie '60s attitude, distribute funds on the basis of other factors such as "community cohesion" and ethnic minority involvement, and are more dysfunctional than the individuals they are supposed to help. He has specifically opposed public funding for the National Empowerment Center , for rejecting the medical model and arguing for a recovery model without necessarily needing medication; it has since lost its funding from

24768-723: The site on March 21, 2014. Upon its completion in 2014, the new One World Trade Center became the tallest skyscraper in the Western Hemisphere, at 1,776 feet (541 m), meant to symbolize the year America gained its independence , 1776. From 2006 to 2018, 3 World Trade Center , 4 World Trade Center , 7   World Trade Center, the World Trade Center Transportation Hub , Liberty Park , and Fiterman Hall were completed. St. Nicholas Greek Orthodox Church and Ronald O. Perelman Performing Arts Center are under construction at

24940-463: The state are the green sea turtle , loggerhead sea turtle , leatherback sea turtle and Kemp's ridley sea turtle . New York Harbor and the Hudson River constitute an estuary , making the state of New York home to a rich array of marine life including shellfish—such as oysters and clams —as well as fish, microorganisms, and sea-birds. Due to its long history, New York has several overlapping and often conflicting definitions of regions within

25112-556: The state's population. The larger Upstate area spreads from the Great Lakes to Lake Champlain and includes the Adirondack Mountains and the Catskill Mountains (part of the wider Appalachian Mountains ). The east–west Mohawk River Valley bisects the more mountainous regions of Upstate and flows into the north–south Hudson River valley near the state capital of Albany . Western New York , home to

25284-639: The structure of the brain to show up more clearly on an X-ray picture). Both first episode psychosis , and high risk status is associated with reductions in grey matter volume (GMV). First episode psychotic and high risk populations are associated with similar but distinct abnormalities in GMV. Reductions in the right middle temporal gyrus , right superior temporal gyrus (STG), right parahippocampus , right hippocampus , right middle frontal gyrus , and left anterior cingulate cortex (ACC) are observed in high risk populations. Reductions in first episode psychosis span

25456-453: The surrounding cultural context. The concept of bizarre delusions has many criticisms, the most prominent being judging its presence is not highly reliable even among trained individuals. A delusion may involve diverse thematic content. The most common type is a persecutory delusion , in which a person believes that an entity seeks to harm them. Others include delusions of reference (the belief that some element of one's experience represents

25628-465: The symptom onset. In both types of catatonia, there is generally no reaction to anything that happens outside of them. It is important to distinguish catatonic agitation from severe bipolar mania, although someone could have both. Negative symptoms include reduced emotional expression , decreased motivation ( avolition ), and reduced spontaneous speech (poverty of speech, alogia ). Individuals with this condition lack interest and spontaneity, and have

25800-529: The term "psychiatric survivor" used by ex-patients to describe themselves was just political correctness and he blamed them, along with civil rights lawyers, for the deaths of half a million people due to suicides and deaths on the street. His comments elicited a record number of letters in response, some in favour of Torrey but most against. The accusations have been described as inflammatory and completely unsubstantiated, and issues of self-determination and self-identity said to be more complex than Torrey realizes. In

25972-490: The town New Amsterdam , which is present-day New York City); and Esopus (1653, now Kingston ). The success of the patroonship of Rensselaerswyck (1630), which surrounded Albany and lasted until the mid-19th century, was also a key factor in the early success of the colony. The English captured the colony during the Second Anglo-Dutch War and governed it as the Province of New York . The city of New York

26144-477: The two planes. Since September   11, most of Lower Manhattan has been restored. In the years since, over 7,000 rescue workers and residents of the area have developed several life-threatening illnesses, and some have died. A memorial at the site, the National September ;11 Memorial & Museum , was opened to the public on September   11, 2011. A permanent museum later opened at

26316-620: The use of seclusion or restraints on the acute admission units. He also volunteered at Washington, D.C. homeless clinics. Torrey is the founder and executive director of the Stanley Medical Research Institute (SMRI), a large, private entity for conducting research on schizophrenia and bipolar disorder in the U.S. SMRI also maintains a collection of postmortem brain tissue from individuals with schizophrenia, bipolar disorder, and major depression and from unaffected controls, which are made available to researchers without charge. After reading Torrey's book Surviving Schizophrenia , Theodore Stanley,

26488-426: The vast majority of the state's geographic area is dominated by meadows , forests , rivers, farms, mountains, and lakes. Most of the southern part of the state rests on the Allegheny Plateau , which extends from the southeastern United States to the Catskill Mountains ; the section in the State of New York is known as the Southern Tier . The rugged Adirondack Mountains , with vast tracts of wilderness, lie west of

26660-605: The views of many members of NAMI including himself. In the 1950s, it was commonly thought that schizophrenia was caused by bad parenting. Torrey has argued that this theory had a toxic effect on parents. His sister had severe schizophrenia and spent most of five decades in hospitals and nursing homes until her death. Torrey has been a fierce opponent of the influence of Sigmund Freud and psychoanalysis . He has also argued that psychiatry should focus only on severe mental illness, conceived as neurological disorders, rather than other mental issues that he viewed as non-medical. Torrey

26832-473: The voice of those consumers, survivors and ex-patients that he disagrees with, opposing their civil rights and censoring and ridiculing their ideas and those of their supporters. Torrey has been a long-time critic of the Center for Mental Health Services that provides support and advocacy, on the grounds that they support anti-psychiatry groups and those opposed to outpatient commitment , claiming they neglect

27004-411: The world in any way while awake. This type of catatonia presents with waxy flexibility . Waxy flexibility is when someone physically moves part of a catatonic person's body and the person stays in the position even if it is bizarre and otherwise nonfunctional (such as moving a person's arm straight up in the air and the arm staying there). The other type of catatonia is more of an outward presentation of

27176-438: The world". MindFreedom suggests that the "links between NAMI and TAC are simply going from overt to covert." In 2002, NAMI's Executive Director issued a statement highly critical of 60 Minutes for producing a piece entitled "Dr. Torrey's War." In the statement, NAMI alternately criticized and backed various positions espoused by Torrey while aiming its criticism at 60 Minutes for what NAMI called "sound bite journalism." Torrey

27348-402: The youth to socialize and work. Potential impairments include reduced speed of mental processing, ability to focus without getting distracted (limited attention span ), and deficits in verbal memory . If an adolescent is experiencing psychosis, they most likely have comorbidity, meaning that they could have multiple mental illnesses. Because of this, it may be difficult to determine whether it

27520-603: Was a common topic, during the Second World War Germany, during the Cold War communists, and in recent years, technology has been a focus. Some psychologists, such as those who practice the Open Dialogue method, believe that the content of psychosis represents an underlying thought process that may, in part, be responsible for psychosis, though the accepted medical position is that psychosis is due to

27692-401: Was a historically prominent symptom, it is rarely seen today. Whether this is due to historically used treatments or the lack thereof is unknown. Catatonia describes a profoundly agitated state in which the experience of reality is generally considered impaired. There are two primary manifestations of catatonic behavior. The classic presentation is a person who does not move or interact with

27864-582: Was a major ocean port and had extensive traffic importing cotton from the South and exporting manufacturing goods. Nearly half of the state's exports were related to cotton. Southern cotton factors, planters and bankers visited so often that they had favorite hotels. At the same time, activism for abolitionism was strong upstate, where some communities provided stops on the Underground Railroad . Upstate, and New York City, gave strong support for

28036-543: Was also the keynote speaker at the 23rd annual NAMI convention in 2002. In 2005, NAMI gave Torrey a tribute on its 25th Anniversary Celebratory Donor Wall, for those who have donated over $ 25,000. It called him a groundbreaking researcher, a ferociously resolute advocate, a prominent and admired author of dozens of books and a dedicated practicing clinician, and said that he had "touched the lives of countless NAMI members throughout this nation." NAMI has some continuing links to TAC via their board of directors. Frederick Frese ,

28208-459: Was around $ 40 million, 74 percent of which was given out to other researchers through grants. As of 2008 SMRI reported that 75% of its expenditure goes towards the development of new treatments. The Stanley Medical Institute in Bethesda, Maryland has collected around 600 brains as of 2008 The SMRI has been sued for allegedly taking brains for use in research without proper consent. One lawsuit

28380-423: Was by expensive wagons on muddy roads before canals opened up the rich farmlands to long-distance traffic. Governor DeWitt Clinton promoted the Erie Canal , which connected New York City to the Great Lakes by the Hudson River , the new canal, and the rivers and lakes. Work commenced in 1817, and the Erie Canal opened eight years later, in 1825. Packet boats pulled by horses on tow paths traveled slowly over

28552-609: Was chosen due its relative isolation with proximity to New York City and the rail lines of Jersey City, New Jersey , via a short ferry ride. While the island was being developed and expanded via land reclamation , the federal government operated a temporary depot at the Barge Office at the Battery. Ellis Island opened on January 1, 1892, and operated as a central immigration center until the National Origins Act

28724-449: Was designed from the start to be "a separate support organization with its own source of funding." According to MindFreedom International , an association of survivors of psychiatric treatment opposed to involuntary treatment, NAMI severed its relationship with TAC because of pressure from groups opposed to Torrey both from within NAMI and outside NAMI. Torrey is, according to MindFreedom, one of "the most feverishly pro-force psychiatrists in

28896-566: Was long afterward celebrated as Evacuation Day . New York City was the national capital under the Articles of Confederation and Perpetual Union , the first national government. That organization was found to be inadequate, and prominent New Yorker Alexander Hamilton advocated for a new government that would include an executive, national courts, and the power to tax. Hamilton led the Annapolis Convention (1786) that called for

29068-536: Was passed in 1924, reducing immigration. After that date, the only immigrants to pass through were displaced persons or war refugees . The island ceased all immigration processing on November 12, 1954, when the last person detained on the island, Norwegian seaman Arne Peterssen, was released. He had overstayed his shore leave and left on the 10:15   a.m. Manhattan-bound ferry to return to his ship. More than 12 million immigrants passed through Ellis Island between 1892 and 1954. More than 100 million Americans across

29240-666: Was principal investigator of a NIMH Schizophrenia/Bipolar Disorder Twin Study conducted at the Neuroscience center of St Elizabeth's Hospital in the late 1980s/early 1990s, and copublished more than a dozen studies on structural brain differences between affected and unaffected siblings. He differed from his collaborators in arguing that the genetic heritability of schizophrenia was lower than typically estimated. A review of Torrey's data analysis, however, suggested he had erroneously compared different sorts of concordance statistics. In

29412-659: Was recaptured by the Dutch in 1673 during the Third Anglo-Dutch War (1672–1674) and renamed New Orange. It was returned to the English under the terms of the Treaty of Westminster a year later. The Sons of Liberty were organized in New York City during the 1760s, largely in response to the oppressive Stamp Act passed by the British Parliament in 1765. The Stamp Act Congress met in

29584-503: Was settled out of court. SMRI reports that it has a close relationship with and is the supporting organization for the Treatment Advocacy Center (TAC). Torrey is a founder of the Treatment Advocacy Center, a national organization that supports outpatient commitment for certain people with mental illness who, in his view of their treatment history and present circumstances, are judged unlikely to survive safely in

#43956