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97-776: The Max Perutz Labs Vienna were founded in 2005, named after the Viennese-born biochemist Max Ferdinand Perutz , who emigrated to England after graduating in Chemistry from the University of Vienna. In Cambridge, he helped to set up the Laboratory of Molecular Biology . He was awarded the Nobel prize in Chemistry together with John Kendrew in 1962, for their studies of the structures of globular proteins . Max Perutz Labs former group leader Emmanuelle Charpentier received

194-701: A candidate for chancellor. Former chancellor Franz von Papen and other conservative leaders convinced President Paul von Hindenburg to appoint Hitler as chancellor on 30 January 1933. Shortly thereafter, the Reichstag passed the Enabling Act of 1933 , which began the process of transforming the Weimar Republic into Nazi Germany, a one-party dictatorship based on the totalitarian and autocratic ideology of Nazism . Upon Hindenburg's death on 2 August 1934, Hitler succeeded him, becoming simultaneously

291-548: A casual labourer and by painting and selling watercolours of Vienna's sights. During his time in Vienna, he pursued a growing passion for architecture and music, attending ten performances of Lohengrin , his favourite Wagner opera. In Vienna, Hitler was first exposed to racist rhetoric. Populists such as mayor Karl Lueger exploited the city's prevalent anti-Semitic sentiment, occasionally also espousing German nationalist notions for political benefit. German nationalism

388-552: A challenge to the government in Berlin. Hitler and Ludendorff sought the support of Staatskommissar (State Commissioner) Gustav Ritter von Kahr , Bavaria's de facto ruler. However, Kahr, along with Police Chief Hans Ritter von Seisser and Reichswehr General Otto von Lossow , wanted to install a nationalist dictatorship without Hitler. On 8 November 1923, Hitler and the SA stormed a public meeting of 3,000 people organised by Kahr in

485-491: A chemistry undergraduate at the University of Vienna and completed his degree in 1936. Made aware by lecturer Fritz von Wessely of the advances being undertaken at the University of Cambridge into biochemistry by a team led by Gowland Hopkins , he asked Professor Mark , who was soon to visit Cambridge, to make inquiries of Hopkins about whether there would be a place for him. Mark forgot, but had visited J.D. Bernal , who

582-677: A classical high school and become an artist, Alois sent Hitler to the Realschule in Linz in September 1900. Hitler rebelled against this decision, and in Mein Kampf states that he intentionally performed poorly in school, hoping that once his father saw "what little progress I was making at the technical school he would let me devote myself to my dream". Like many Austrian Germans, Hitler began to develop German nationalist ideas from

679-470: A crowd of over 6,000. To publicise the meeting, two truckloads of party supporters drove around Munich waving swastika flags and distributing leaflets. Hitler soon gained notoriety for his rowdy polemic speeches against the Treaty of Versailles, rival politicians, and especially against Marxists and Jews. In June 1921, while Hitler and Eckart were on a fundraising trip to Berlin , a mutiny broke out within

776-473: A letter to Hindenburg. The signers urged Hindenburg to appoint Hitler as leader of a government "independent from parliamentary parties", which could turn into a movement that would "enrapture millions of people". Hindenburg reluctantly agreed to appoint Hitler as chancellor after two further parliamentary elections—in July and November 1932—had not resulted in the formation of a majority government. Hitler headed

873-702: A matter of debate. His friend August Kubizek claimed that Hitler was a "confirmed anti-Semite" before he left Linz. However, historian Brigitte Hamann describes Kubizek's claim as "problematical". While Hitler states in Mein Kampf that he first became an anti-Semite in Vienna, Reinhold Hanisch , who helped him sell his paintings, disagrees. Hitler had dealings with Jews while living in Vienna. Historian Richard J. Evans states that "historians now generally agree that his notorious, murderous anti-Semitism emerged well after Germany's defeat [in World War I], as

970-528: A meeting with the Prime Minister of Bavaria, Heinrich Held , on 4 January 1925, Hitler agreed to respect the state's authority and promised that he would seek political power only through the democratic process. The meeting paved the way for the ban on the Nazi Party to be lifted on 16 February. However, after an inflammatory speech he gave on 27 February, Hitler was barred from public speaking by

1067-523: A member of Peterhouse , on the basis that it served the best food. He was elected an Honorary Fellow of Peterhouse in 1962. He took a keen interest in the Junior Members, and was a regular and popular speaker at the Kelvin Club, the college's scientific society. When Hitler took over Austria in 1938, Perutz's parents managed to escape to Switzerland, but they had lost all of their money. As

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1164-413: A molecular machine: how it switches between its deoxygenated and its oxygenated states, in turn triggering the uptake of oxygen and then its release to the muscles and other organs. Further work over the next two decades refined and corroborated the proposed mechanism. In addition Perutz studied the structural changes in a number of haemoglobin diseases and how these might affect oxygen binding. He hoped that

1261-889: A number of other important honours: he was appointed a Commander of the Order of the British Empire in 1963, elected to the American Academy of Arts and Sciences that same year, received the Austrian Decoration for Science and Art in 1967, was elected to the American Philosophical Society in 1968, elected to the United States National Academy of Sciences in 1970, received the Royal Medal of

1358-563: A process of hypothesis formation and refutation, saying that hypotheses are not necessarily the basis of scientific research and, in molecular biology at least, they are not necessarily subject to revision either. For Perutz, Kuhn's notion that science advances in paradigm shifts that are subject to social and cultural pressures is an unfair representation of modern science. These criticisms extended to scientists who attack religion, in particular to Dawkins. Statements which offend people's religious faith were for Perutz tactless and simply damage

1455-546: A product of the paranoid "stab-in-the-back" explanation for the catastrophe". Hitler received the final part of his father's estate in May 1913 and moved to Munich , Germany. When he was conscripted into the Austro-Hungarian Army , he journeyed to Salzburg on 5 February 1914 for medical assessment. After he was deemed unfit for service, he returned to Munich. Hitler later claimed that he did not wish to serve

1552-681: A recommendation by Lieutenant Hugo Gutmann , his Jewish superior, Hitler received the Iron Cross, First Class, a decoration rarely awarded at Hitler's Gefreiter rank. On 15 October 1918, he was temporarily blinded in a mustard gas attack and was hospitalised in Pasewalk . While there, Hitler learned of Germany's defeat, and, by his own account, suffered a second bout of blindness after receiving this news. Hitler described his role in World War I as "the greatest of all experiences", and

1649-549: A result of military action in the European theatre . The number of civilians killed during World War II was unprecedented in warfare, and the casualties constitute the deadliest conflict in history . Hitler's father, Alois Hitler (1837–1903), was the illegitimate child of Maria Schicklgruber . The baptismal register did not show the name of his father, and Alois initially bore his mother's surname, "Schicklgruber". In 1842, Johann Georg Hiedler married Alois's mother. Alois

1746-585: A result, Perutz lost their financial support. With his ability to ski, experience in mountaineering since childhood and his knowledge of crystals, Perutz was accepted as a member of a three-man team to study the conversion of snow into ice in Swiss glaciers in the summer of 1938. His resulting article for the Proceedings of the Royal Society made him known as an expert on glaciers. Lawrence Bragg, who

1843-651: A short-lived coalition government formed by the Nazi Party (which had the most seats in the Reichstag) and Hugenberg's party, the German National People's Party (DNVP). On 30 January 1933, the new cabinet was sworn in during a brief ceremony in Hindenburg's office. The Nazi Party gained three posts: Hitler was named chancellor, Wilhelm Frick Minister of the Interior, and Hermann Göring Minister of

1940-515: A special party congress on 29 July, he was granted absolute power as party chairman, succeeding Drexler, by a vote of 533 to 1. Hitler's vitriolic beer hall speeches began attracting regular audiences. A demagogue , he became adept at using populist themes, including the use of scapegoats , who were blamed for his listeners' economic hardships. Hitler used personal magnetism and an understanding of crowd psychology to his advantage while engaged in public speaking. Historians have noted

2037-726: A talk she gave in late 1951, which Watson had attended. Perutz also added that the report was addressed to an MRC committee created to "establish contact between the different groups of people working for the Council". Randall's and Perutz's labs were both funded by the MRC. In his later years, Perutz was a regular reviewer/essayist for The New York Review of Books on biomedical subjects. Many of these essays are reprinted in his 1998 book, I wish I had made you angry earlier . In August 1985, The New Yorker published his account of his experiences as an internee during World War II, titled "That Was

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2134-481: A young age. He expressed loyalty only to Germany, despising the declining Habsburg monarchy and its rule over an ethnically diverse empire. Hitler and his friends used the greeting "Heil", and sang the " Deutschlandlied " instead of the Austrian Imperial anthem . After Alois's sudden death on 3 January 1903, Hitler's performance at school deteriorated and his mother allowed him to leave. He enrolled at

2231-609: Is that van der Lubbe set the fire alone. At Hitler's urging, Hindenburg responded by signing the Reichstag Fire Decree of 28 February, drafted by the Nazis, which suspended basic rights and allowed detention without trial. The decree was permitted under Article 48 of the Weimar Constitution, which gave the president the power to take emergency measures to protect public safety and order. Activities of

2328-538: Is undeniable", according to Ian Kershaw . Published in two volumes in 1925 and 1926, Mein Kampf sold 228,000 copies between 1925 and 1932. One million copies were sold in 1933, Hitler's first year in office. Shortly before Hitler was eligible for parole, the Bavarian government attempted to have him deported to Austria. The Austrian federal chancellor rejected the request on the specious grounds that his service in

2425-580: The 1932 presidential elections . A speech to the Industry Club in Düsseldorf on 27 January 1932 won him support from many of Germany's most powerful industrialists. Hindenburg had support from various nationalist, monarchist, Catholic, and republican parties, and some Social Democrats . Hitler used the campaign slogan " Hitler über Deutschland " ("Hitler over Germany"), a reference to his political ambitions and his campaigning by aircraft. He

2522-699: The Battle of the Somme in October 1916, he was wounded in the left thigh when a shell exploded in the dispatch runners' dugout. Hitler spent almost two months recovering in hospital at Beelitz , returning to his regiment on 5 March 1917. He was present at the Battle of Arras of 1917 and the Battle of Passchendaele . He received the Black Wound Badge on 18 May 1918. Three months later, in August 1918, on

2619-1003: The Bavarian Reserve Infantry Regiment 16 (1st Company of the List Regiment), he served as a dispatch runner on the Western Front in France and Belgium, spending nearly half his time at the regimental headquarters in Fournes-en-Weppes , well behind the front lines. In 1914, he was present at the First Battle of Ypres and in that year was decorated for bravery, receiving the Iron Cross , Second Class. During his service at headquarters, Hitler pursued his artwork, drawing cartoons and instructions for an army newspaper. During

2716-604: The Bürgerbräukeller , a beer hall in Munich. Interrupting Kahr's speech, he announced that the national revolution had begun and declared the formation of a new government with Ludendorff. Retiring to a back room, Hitler, with his pistol drawn, demanded and subsequently received the support of Kahr, Seisser, and Lossow. Hitler's forces initially succeeded in occupying the local Reichswehr and police headquarters, but Kahr and his cohorts quickly withdrew their support. Neither

2813-463: The Centre Party , governed through emergency decrees from President Paul von Hindenburg . Governance by decree became the new norm and paved the way for authoritarian forms of government. The Nazi Party rose from obscurity to win 18.3 per cent of the vote and 107 parliamentary seats in the 1930 election, becoming the second-largest party in parliament. Hitler made a prominent appearance at

2910-589: The German Communist Party (KPD) were suppressed, and some 4,000 KPD members were arrested. In addition to political campaigning, the Nazi Party engaged in paramilitary violence and the spread of anti-communist propaganda in the days preceding the election . On election day, 6 March 1933, the Nazi Party's share of the vote increased to 43.9 per cent, and the party acquired the largest number of seats in parliament. Hitler's party failed to secure an absolute majority, necessitating another coalition with

3007-594: The Habsburg Empire because of the mixture of races in its army and his belief that the collapse of Austria-Hungary was imminent. In August 1914, at the outbreak of World War I , Hitler was living in Munich and voluntarily enlisted in the Bavarian Army . According to a 1924 report by the Bavarian authorities, allowing Hitler to serve was most likely an administrative error, because as an Austrian citizen, he should have been returned to Austria. Posted to

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3104-585: The Iron Cross . In 1919, he joined the German Workers' Party (DAP), the precursor of the Nazi Party, and in 1921 was appointed leader of the Nazi Party. In 1923, he attempted to seize governmental power in a failed coup in Munich and was sentenced to five years in prison, serving just over a year of his sentence. While there, he dictated the first volume of his autobiography and political manifesto Mein Kampf ( My Struggle ). After his early release in 1924, Hitler gained popular support by attacking

3201-649: The Realschule in Steyr in September 1904, where his behaviour and performance improved. In 1905, after passing a repeat of the final exam, Hitler left the school without any ambitions for further education or clear plans for a career. In 1907, Hitler left Linz to live and study fine art in Vienna , financed by orphan's benefits and support from his mother. He applied for admission to the Academy of Fine Arts Vienna but

3298-460: The Reichstag building was set on fire . Göring blamed a communist plot, as Dutch communist Marinus van der Lubbe was found in incriminating circumstances inside the burning building. Until the 1960s, some historians, including William L. Shirer and Alan Bullock , thought the Nazi Party itself was responsible; according to Ian Kershaw, writing in 1998, the view of nearly all modern historians

3395-808: The Royal Society in 1971, appointed a Member of the Order of the Companions of Honour in 1975, received the Copley Medal in 1979 and became a Member of the Order of Merit in 1988. Perutz was made a Member of the German Academy of Sciences Leopoldina in 1964, received an Honorary doctorate from the University of Vienna (1965) and received the Wilhelm Exner Medal in 1967. He was elected to EMBO Membership in 1964. The European Crystallographic Association established

3492-513: The Treaty of Versailles and promoting pan-Germanism , antisemitism , and anti-communism with charismatic oratory and Nazi propaganda . He frequently denounced communism as being part of an international Jewish conspiracy . By November 1932, the Nazi Party held the most seats in the Reichstag , but not a majority. No political parties were able to form a majority coalition in support of

3589-630: The University of York . Gisela was a refugee from Germany (she was a Protestant whose own father had been born Jewish). He died on 6 February 2002 and his ashes were interred with his parents Hugo Perutz and Dely Perutz in the Parish of the Ascension Burial Ground in Cambridge. Gisela died on 17 December 2005 and her ashes were interred in the same grave. Adolf Hitler Adolf Hitler (20 April 1889 – 30 April 1945)

3686-473: The parliamentary republic , which faced challenges from right- and left-wing extremists . The moderate political parties were increasingly unable to stem the tide of extremism, and the German referendum of 1929 helped to elevate Nazi ideology. The elections of September 1930 resulted in the break-up of a grand coalition and its replacement with a minority cabinet. Its leader, chancellor Heinrich Brüning of

3783-495: The "Nazi Party"). Hitler designed the party's banner of a swastika in a white circle on a red background. Hitler was discharged from the Army on 31 March 1920 and began working full-time for the party. The party headquarters was in Munich, a centre for anti-government German nationalists determined to eliminate Marxism and undermine the Weimar Republic . In February 1921—already highly effective at crowd manipulation —he spoke to

3880-659: The 2015 Breakthrough Prize in Life Sciences and the 2020 Nobel Prize in Chemistry for her work on the CRISPR/Cas9 system, done partly in Vienna. As of June 2019, scientists of the Max Perutz Labs have been awarded 14 ERC grants. 48°11′18″N 16°24′04″E  /  48.1883°N 16.4010°E  / 48.1883; 16.4010 Max Perutz Max Ferdinand Perutz OM CH CBE FRS (19 May 1914 – 6 February 2002)

3977-475: The Army nor the state police joined forces with Hitler. The next day, Hitler and his followers marched from the beer hall to the Bavarian War Ministry to overthrow the Bavarian government, but police dispersed them. Sixteen Nazi Party members and four police officers were killed in the failed coup. Hitler fled to the home of Ernst Hanfstaengl and by some accounts contemplated suicide. He

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4074-573: The Army. In July 1919, he was appointed Verbindungsmann (intelligence agent) of an Aufklärungskommando (reconnaissance unit) of the Reichswehr , assigned to influence other soldiers and to infiltrate the German Workers' Party (DAP). At a DAP meeting on 12 September 1919, Party Chairman Anton Drexler was impressed by Hitler's oratorical skills. He gave him a copy of his pamphlet My Political Awakening , which contained anti-Semitic, nationalist, anti-capitalist , and anti-Marxist ideas. On

4171-624: The Bavarian Supreme Court, he was released from jail on 20 December 1924, against the state prosecutor's objections. Including time on remand, Hitler served just over one year in prison. While at Landsberg, Hitler dictated most of the first volume of Mein Kampf ( lit.   ' My Struggle ' ); originally titled Four and a Half Years of Struggle against Lies, Stupidity, and Cowardice ) at first to his chauffeur, Emil Maurice , and then to his deputy, Rudolf Hess . The book, dedicated to Thule Society member Dietrich Eckart,

4268-404: The Bavarian authorities, a ban that remained in place until 1927. To advance his political ambitions in spite of the ban, Hitler appointed Gregor Strasser , Otto Strasser , and Joseph Goebbels to organise and enlarge the Nazi Party in northern Germany. Gregor Strasser steered a more independent political course, emphasising the socialist elements of the party's programme. The stock market in

4365-657: The DNVP. On 21 March 1933, the new Reichstag was constituted with an opening ceremony at the Garrison Church in Potsdam . This "Day of Potsdam" was held to demonstrate unity between the Nazi movement and the old Prussian elite and military. Hitler appeared in a morning coat and humbly greeted Hindenburg. To achieve full political control despite not having an absolute majority in parliament, Hitler's government brought

4462-433: The German Army made his Austrian citizenship void. In response, Hitler formally renounced his Austrian citizenship on 7 April 1925. At the time of Hitler's release from prison, politics in Germany had become less combative and the economy had improved, limiting Hitler's opportunities for political agitation. As a result of the failed Beer Hall Putsch, the Nazi Party and its affiliated organisations were banned in Bavaria. In

4559-403: The Interior for Prussia. Hitler had insisted on the ministerial positions as a way to gain control over the police in much of Germany. As chancellor, Hitler worked against attempts by the Nazi Party's opponents to build a majority government. Because of the political stalemate, he asked Hindenburg to again dissolve the Reichstag, and elections were scheduled for early March. On 27 February 1933,

4656-403: The Max Perutz Prize, named in his honour. In 1980, Perutz was invited to deliver one of the six lectures for the Royal Institution Christmas Lectures on The Chicken, the Egg and the Molecules . In 1942, Perutz married Gisela Clara Mathilde Peiser (1915–2005), a medical photographer. They had two children, Vivien (b. 1944), an art historian; and Robin (b. 1949), a professor of chemistry at

4753-446: The Nazi Party in Munich. Members of its executive committee wanted to merge with the Nuremberg-based German Socialist Party (DSP). Hitler returned to Munich on 11 July and angrily tendered his resignation. The committee members realised that the resignation of their leading public figure and speaker would mean the end of the party. Hitler announced he would rejoin on the condition that he would replace Drexler as party chairman, and that

4850-404: The Nazi regime was responsible for the genocide of an estimated six million Jews and millions of other victims, whom he and his followers deemed Untermenschen (subhumans) or socially undesirable. Hitler and the Nazi regime were also responsible for the deliberate killing of an estimated 19.3 million civilians and prisoners of war. In addition, 28.7 million soldiers and civilians died as

4947-400: The Nazis' paramilitary organisation, the Sturmabteilung (SA, "Stormtroopers"), which protected meetings and attacked political opponents. A critical influence on Hitler's thinking during this period was the Aufbau Vereinigung , a conspiratorial group of White Russian exiles and early Nazis. The group, financed with funds channelled from wealthy industrialists, introduced Hitler to

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5044-437: The United States crashed on 24 October 1929 . The impact in Germany was dire: millions became unemployed and several major banks collapsed. Hitler and the Nazi Party prepared to take advantage of the emergency to gain support for their party. They promised to repudiate the Versailles Treaty, strengthen the economy, and provide jobs. The Great Depression provided a political opportunity for Hitler. Germans were ambivalent about

5141-642: The United States . By the end of 1941, German forces and the European Axis powers occupied most of Europe and North Africa . These gains were gradually reversed after 1941, and in 1945 the Allied armies defeated the German army. On 29 April 1945, he married his longtime partner, Eva Braun , in the Führerbunker in Berlin. The couple committed suicide the next day to avoid capture by the Soviet Red Army . In accordance with Hitler's wishes, their corpses were burned. The historian and biographer Ian Kershaw described Hitler as "the embodiment of modern political evil". Under Hitler's leadership and racist ideology ,

5238-447: The War he returned briefly to glaciology, demonstrating how glaciers flow. In 1947, Perutz, with the support of Professor Bragg, was successful in obtaining support from the Medical Research Council (MRC) to undertake research into the molecular structure of biological systems. This financial support allowed him to establish the Molecular Biology Unit at the Cavendish Laboratory. Perutz's new unit attracted researchers who realised that

5335-480: The War: Enemy Alien". Perutz won the Lewis Thomas Prize for Writing about Science in 1997. A collection of Perutz's correspondence was published posthumously in 2009, titled What a Time I Am Having: Selected Letters of Max Perutz . Perutz attacked the theories of philosophers Sir Karl Popper and Thomas Kuhn and biologist Richard Dawkins in a lecture given at Cambridge on 'Living Molecules' in 1994. He criticised Popper's notion that science progresses through

5432-399: The X-ray diffraction method to study the structure of proteins. As protein crystals were difficult to obtain, he used horse haemoglobin crystals, and began his doctoral thesis on its structure. Haemoglobin was a subject which was to occupy him for most of his professional career. He completed his Ph.D. under Lawrence Bragg in 1940. He applied to Kings and St. John's colleges, and became

5529-485: The aim of the government "must unshakably be the removal of the Jews altogether". At the DAP, Hitler met Dietrich Eckart , one of the party's founders and a member of the occult Thule Society . Eckart became Hitler's mentor, exchanging ideas with him and introducing him to a wide range of Munich society. To increase its appeal, the DAP changed its name to the Nationalsozialistische Deutsche Arbeiterpartei ( National Socialist German Workers' Party (NSDAP), now known as

5626-414: The blood. This work resulted in his sharing with John Kendrew the 1962 Nobel Prize for Chemistry . Nowadays the molecular structures of several thousand proteins are determined by X-ray crystallography every year. After 1959, Perutz and his colleagues went on to determine the structure of oxy- and deoxy- haemoglobin at high resolution. As a result, in 1970, he was at last able to suggest how it works as

5723-499: The claim that Alois's father was Jewish. Adolf Hitler was born on 20 April 1889 in Braunau am Inn , a town in Austria-Hungary (present-day Austria), close to the border with the German Empire . He was the fourth of six children born to Alois Hitler and his third wife, Klara Pölzl . Three of Hitler's siblings—Gustav, Ida, and Otto—died in infancy. Also living in the household were Alois's children from his second marriage: Alois Jr. (born 1882) and Angela (born 1883). When Hitler

5820-439: The country. Many Germans saw the treaty as an unjust humiliation. They especially objected to Article 231 , which they interpreted as declaring Germany responsible for the war. The Versailles Treaty and the economic, social, and political conditions in Germany after the war were later exploited by Hitler for political gain. After World War I, Hitler returned to Munich. Without formal education or career prospects, he remained in

5917-451: The death of thousands more innocent people, driving us into a world of escalating terror and counter-terror. I do hope that you can use your restraining influence to prevent this happening." Perutz was elected a Fellow of the Royal Society (FRS) in 1954 . In addition to the Nobel Prize for Chemistry in 1962, which he shared with John Kendrew for their respective studies of the structures of haemoglobin and myoglobin, Max Perutz received

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6014-458: The double-helix structure. Perutz did this without Franklin's knowledge or permission, and before she had a chance to publish a detailed analysis of the content of her unpublished progress report. Later this action was criticised by Randall and others, in view of the results and the honours resulting from this "gift". In an effort to clarify this issue, Perutz later published the report, arguing that it included nothing that Franklin had not said in

6111-468: The family moved to Lambach. The eight-year-old Hitler took singing lessons, sang in the church choir, and even considered becoming a priest. In 1898, the family returned permanently to Leonding. Hitler was deeply affected by the death of his younger brother Edmund in 1900 from measles . Hitler changed from a confident, outgoing, conscientious student to a morose, detached boy who constantly fought with his father and teachers. Paula Hitler recalled how Adolf

6208-432: The field of molecular biology had great promise; among them were Francis Crick in 1949 and James D. Watson in 1951. In 1953, Perutz showed that diffracted X-rays from protein crystals could be phased by comparing the patterns from crystals of the protein with and without heavy atoms attached. In 1959 he employed this method to determine the molecular structure of the protein haemoglobin , which transports oxygen in

6305-406: The field", had been "stabbed in the back" on the home front by civilian leaders, Jews, Marxists , and those who signed the armistice that ended the fighting—later dubbed the "November criminals". The Treaty of Versailles stipulated that Germany had to relinquish several of its territories and demilitarise the Rhineland . The treaty imposed economic sanctions and levied heavy reparations on

6402-478: The head of state and government, with absolute power. Domestically, Hitler implemented numerous racist policies and sought to deport or kill German Jews . His first six years in power resulted in rapid economic recovery from the Great Depression , the abrogation of restrictions imposed on Germany after World War I, and the annexation of territories inhabited by millions of ethnic Germans, which initially gave him significant popular support. One of Hitler's key goals

6499-554: The hypnotic effect of his rhetoric on large audiences, and of his eyes in small groups. Alfons Heck , a former member of the Hitler Youth, recalled: We erupted into a frenzy of nationalistic pride that bordered on hysteria. For minutes on end, we shouted at the top of our lungs, with tears streaming down our faces: Sieg Heil, Sieg Heil, Sieg Heil! From that moment on, I belonged to Adolf Hitler body and soul. Early followers included Rudolf Hess , former air force ace Hermann Göring , and army captain Ernst Röhm . Röhm became head of

6596-477: The idea of a Jewish conspiracy, linking international finance with Bolshevism . The programme of the Nazi Party was laid out in their 25-point programme on 24 February 1920. This did not represent a coherent ideology, but was a conglomeration of received ideas which had currency in the völkisch Pan-Germanic movement, such as ultranationalism , opposition to the Treaty of Versailles , distrust of capitalism , as well as some socialist ideas. For Hitler,

6693-455: The meaning "one who lives in a hut". Nazi official Hans Frank suggested that Alois's mother had been employed as a housekeeper by a Jewish family in Graz , and that the family's 19-year-old son Leopold Frankenberger had fathered Alois, a claim that came to be known as the Frankenberger thesis . No Frankenberger was registered in Graz during that period, no record has been produced of Leopold Frankenberger's existence, so historians dismiss

6790-485: The molecule could be made to function as a drug receptor and that it would be possible to inhibit or reverse the genetic errors such as those that occur in sickle cell anaemia . A further interest was the variation of the haemoglobin molecule from species to species to suit differing habitats and patterns of behaviour. In his final years Perutz turned to the study of changes in protein structures implicated in Huntington and other neurodegenerative diseases. He demonstrated that

6887-523: The most important aspect of it was its strong anti-Semitic stance. He also perceived the programme as primarily a basis for propaganda and for attracting people to the party. In 1923, Hitler enlisted the help of World War I General Erich Ludendorff for an attempted coup known as the " Beer Hall Putsch ". The Nazi Party used Italian Fascism as a model for their appearance and policies. Hitler wanted to emulate Benito Mussolini 's " March on Rome " of 1922 by staging his own coup in Bavaria, to be followed by

6984-531: The officer corps. Brüning's austerity measures brought little economic improvement and were extremely unpopular. Hitler exploited this by targeting his political messages specifically at people who had been affected by the inflation of the 1920s and the Depression, such as farmers, war veterans, and the middle class. Although Hitler had terminated his Austrian citizenship in 1925, he did not acquire German citizenship for almost seven years. This meant that he

7081-544: The onset of Huntington disease is related to the number of glutamine repeats as they bind to form what he called a "polar zipper". During the early 1950s, while Watson and Crick were trying to determine the structure of deoxyribonucleic acid (DNA), they were given by Perutz an unpublished 1952 progress report for the King's College laboratory of Sir John Randall . This report contained X-ray diffraction images taken by Rosalind Franklin that proved to be crucial in coming to

7178-413: The onset of intense father-son conflicts caused by Hitler's refusal to conform to the strict discipline of his school. Alois tried to browbeat his son into obedience, while Adolf did his best to be the opposite of whatever his father wanted. Alois would also beat his son, although his mother tried to protect him from regular beatings. Alois Hitler's farming efforts at Hafeld ended in failure, and in 1897

7275-523: The orders of his army superiors, Hitler applied to join the party, and within a week was accepted as party member 555 (the party began counting membership at 500 to give the impression they were a much larger party). Hitler made his earliest known written statement about the Jewish question in a 16 September 1919 letter to Adolf Gemlich (now known as the Gemlich letter ). In the letter, Hitler argues that

7372-518: The party headquarters would remain in Munich. The committee agreed, and he rejoined the party on 26 July as member 3,680. Hitler continued to face some opposition within the Nazi Party. Opponents of Hitler in the leadership had Hermann Esser expelled from the party, and they printed 3,000 copies of a pamphlet attacking Hitler as a traitor to the party. In the following days, Hitler spoke to several large audiences and defended himself and Esser, to thunderous applause. His strategy proved successful, and at

7469-597: The reputation of science, though he did not criticize scientists opposing "demonstrably false" theories such as creationism . He concluded that "even if we do not believe in God, we should try to live as though we did." Within days of the 11 September attacks in 2001, Perutz wrote to British Prime Minister Tony Blair , appealing to him to not respond with military force: "I am alarmed by the American cries for vengeance and concerned that President Bush's retaliation will lead to

7566-476: The subject of ice then led to him being recruited for Project Habakkuk in 1942. This was a secret project to build an ice platform in the mid-Atlantic, which could be used to refuel aircraft. To that end he investigated the recently invented mixture of ice and woodpulp known as pykrete . He carried out early experiments on pykrete in a secret location underneath Smithfield Meat Market in the City of London . After

7663-490: The trial of two Reichswehr officers, Lieutenants Richard Scheringer and Hanns Ludin , in late 1930. Both were charged with membership in the Nazi Party, at that time illegal for Reichswehr personnel. The prosecution argued that the Nazi Party was an extremist party, prompting defence lawyer Hans Frank to call on Hitler to testify. On 25 September 1930, Hitler testified that his party would pursue political power solely through democratic elections, which won him many supporters in

7760-690: The war and was central to the perpetration of the Holocaust : the genocide of about six million Jews and millions of other victims . Hitler was born in Braunau am Inn in Austria-Hungary and was raised near Linz . He lived in Vienna in the first decade of the 1900s before moving to Germany in 1913. He was decorated during his service in the German Army in World War I , receiving

7857-679: Was Lebensraum ( lit.   ' living space ' ) for the German people in Eastern Europe, and his aggressive, expansionist foreign policy is considered the primary cause of World War II in Europe . He directed large-scale rearmament and, on 1 September 1939, invaded Poland, causing Britain and France to declare war on Germany . In June 1941, Hitler ordered an invasion of the Soviet Union . In December 1941, he declared war on

7954-524: Was rounded up along with other persons of German or Austrian background , and sent to Newfoundland (on orders from Winston Churchill). After being interned for several months he returned to Cambridge. Because of his pre-War research into the changes in the arrangement of the crystals in the layers of a glacier, he was asked for advice on whether if a battalion of commandos were landed in Norway, could they be hidden in shelters under glaciers. His knowledge on

8051-457: Was stateless , legally unable to run for public office, and still faced the risk of deportation. On 25 February 1932, the interior minister of Brunswick , Dietrich Klagges , who was a member of the Nazi Party, appointed Hitler as administrator for the state's delegation to the Reichsrat in Berlin, making Hitler a citizen of Brunswick, and thus of Germany. Hitler ran against Hindenburg in

8148-639: Was Professor of Experimental Physics at the Cavendish, thought that Perutz's research into haemoglobin had promise and encouraged him to apply for a grant from the Rockefeller Foundation to continue his research. The application was accepted in January 1939 and with the money Perutz was able to bring his parents from Switzerland to England in March 1939. On the outbreak of World War II, Perutz

8245-418: Was a teenage bully who would often slap her. Alois had made a successful career in the customs bureau and wanted his son to follow in his footsteps. Hitler later dramatised an episode from this period when his father took him to visit a customs office, depicting it as an event that gave rise to an unforgiving antagonism between father and son, who were both strong-willed. Ignoring his son's desire to attend

8342-504: Was an Austrian-born British molecular biologist , who shared the 1962 Nobel Prize for Chemistry with John Kendrew , for their studies of the structures of haemoglobin and myoglobin . He went on to win the Royal Medal of the Royal Society in 1971 and the Copley Medal in 1979. At Cambridge he founded and chaired (1962–79) The MRC Laboratory of Molecular Biology (LMB), fourteen of whose scientists have won Nobel Prizes. Perutz

8439-554: Was an Austrian-born German politician who was the dictator of Nazi Germany from 1933 until his suicide in 1945. He rose to power as the leader of the Nazi Party , becoming the chancellor in 1933 and then taking the title of Führer und Reichskanzler in 1934. His invasion of Poland on 1 September 1939 marked the start of the Second World War . He was closely involved in military operations throughout

8536-428: Was an autobiography and exposition of his ideology. The book laid out Hitler's plans for transforming German society into one based on race. Throughout the book, Jews are equated with "germs" and presented as the "international poisoners" of society. According to Hitler's ideology, the only solution was their extermination. While Hitler did not describe exactly how this was to be accomplished, his "inherent genocidal thrust

8633-536: Was born in Vienna , the son of Adele "Dely" (Goldschmidt) and Hugo Perutz, a textile manufacturer. His parents were Jewish by ancestry, but had baptised Perutz in the Catholic religion. Although Perutz rejected religion and was an atheist in his later years, he was against offending others for their religious beliefs. His parents hoped that he would become a lawyer, but he became interested in chemistry while at school. Overcoming his parents' objections he enrolled as

8730-437: Was brought up in the family of Hiedler's brother, Johann Nepomuk Hiedler . In 1876, Alois was made legitimate and his baptismal record annotated by a priest to register Johann Georg Hiedler as Alois's father (recorded as "Georg Hitler"). Alois then assumed the surname "Hitler", also spelled "Hiedler", "Hüttler" , or "Huettler" . The name is probably based on the German word Hütte ( lit.   ' hut ' ), and has

8827-507: Was depressed but calm when arrested on 11 November 1923 for high treason . His trial before the special People's Court in Munich began in February 1924, and Alfred Rosenberg became temporary leader of the Nazi Party. On 1 April, Hitler was sentenced to five years' imprisonment at Landsberg Prison . There, he received friendly treatment from the guards, and was allowed mail from supporters and regular visits by party comrades. Pardoned by

8924-802: Was even more widespread in the Mariahilf district, where Hitler then lived. Georg Ritter von Schönerer became a major influence on Hitler, and he developed an admiration for Martin Luther . Hitler read local newspapers that promoted prejudice and utilised Christian fears of being swamped by an influx of Eastern European Jews as well as pamphlets that published the thoughts of philosophers and theoreticians such as Houston Stewart Chamberlain , Charles Darwin , Friedrich Nietzsche , Gustave Le Bon , and Arthur Schopenhauer . During his life in Vienna, Hitler also developed fervent anti-Slavic sentiments . The origin and development of Hitler's anti-Semitism remains

9021-499: Was looking for a research student to assist him with studies into X-ray crystallography. Perutz was dismayed as he knew nothing about the subject. Mark countered by saying that he would soon learn. Bernal accepted him as a research student in his crystallography research group at the Cavendish Laboratory . His father had deposited £500 with his London agent to support him. He learnt quickly. Bernal encouraged him to use

9118-510: Was one of the first politicians to use aircraft travel for campaigning and used it effectively. Hitler came in second in both rounds of the election, garnering more than 35 per cent of the vote in the final election. Although he lost to Hindenburg, this election established Hitler as a strong force in German politics. The absence of an effective government prompted two influential politicians, Franz von Papen and Alfred Hugenberg , along with several other industrialists and businessmen, to write

9215-527: Was praised by his commanding officers for his bravery. His wartime experience reinforced his German patriotism, and he was shocked by Germany's capitulation in November 1918. His displeasure with the collapse of the war effort began to shape his ideology. Like other German nationalists, he believed the Dolchstoßlegende ( stab-in-the-back myth ), which claimed that the German army, "undefeated in

9312-566: Was rejected twice. The director suggested Hitler should apply to the School of Architecture, but he lacked the necessary academic credentials because he had not finished secondary school. On 21 December 1907, his mother died of breast cancer at the age of 47; Hitler was 18 at the time. In 1909, Hitler ran out of money and was forced to live a bohemian life in homeless shelters and the Meldemannstraße dormitory . He earned money as

9409-578: Was three, the family moved to Passau , Germany. There he acquired the distinctive lower Bavarian dialect , rather than Austrian German , which marked his speech throughout his life. The family returned to Austria and settled in Leonding in 1894, and in June 1895 Alois retired to Hafeld, near Lambach , where he farmed and kept bees. Hitler attended Volksschule (a state-funded primary school) in nearby Fischlham . The move to Hafeld coincided with

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