34°57′S 150°30′W / 34.950°S 150.500°W / -34.950; -150.500
151-656: The Mysterious Island ( French : L'Île mystérieuse ) is a novel by Jules Verne , serialised from August 1874 to September 1875 and then published in book form in November 1875 . The first edition, published by Hetzel , contains illustrations by Jules Férat . The novel is a crossover sequel to Verne's famous Twenty Thousand Leagues Under the Seas (1870) and In Search of the Castaways (1867–68), though its themes are vastly different from those books. An early draft of
302-425: A message in a bottle directing them to rescue a castaway on nearby Tabor Island , who is none other than Tom Ayrton (from In Search of the Castaways ). On the return voyage to Lincoln Island, they lose their way in a tempest but are guided back to their course by a mysterious fire beacon. Ayrton's former companions arrive by chance on Lincoln Island and try to make it into their lair. After some fighting with
453-896: A sailor (who is addressed only by his surname; in Kingston's version, he is named Pencroft); his protégé and adopted son Harbert Brown (called Herbert in some translations); and the journalist Gedéon Spilett (Gideon Spilett in English versions). The company is completed by Cyrus's dog "Top". After flying in a great storm for several days, the group crash-lands on a cliff-bound, volcanic, unknown island , described as being located at 34°57′S 150°30′W / 34.950°S 150.500°W / -34.950; -150.500 (Southern Pacific Ocean/Asian:Oceanian side), about 2,500 kilometres (1,600 mi) east of New Zealand and about 11,000 kilometres (6,800 mi) from Virginia. They name it "Lincoln Island" in honor of Abraham Lincoln . With
604-602: A Deserted Island", and has a cult following in Maharashtra . The novel has also been translated to Malayalam , as Nigoodadweep , translated by Kesavan Nambisan. There are more than one translation in Bengali . The translation by Kuladaranjan Roy is called “আশ্চর্য দ্বীপ” (Aschorjo Dwip) and has been republished by Kalpabiswa Publications in 2023. Another translation by Shamsuddin Nawab from Sheba Prokashoni published in 1979
755-744: A French official to teachers in the department of Finistère , in western Brittany, included the following: "And remember, Gents: you were given your position in order to kill the Breton language". The prefect of Basses-Pyrénées in the French Basque Country wrote in 1846: "Our schools in the Basque Country are particularly meant to replace the Basque language with French..." Students were taught that their ancestral languages were inferior and they should be ashamed of them; this process
906-575: A blood meal from a previously Plasmodium infected person or animal. Parasites are then typically introduced by the bite of an infected Anopheles mosquito. Some of these inoculated parasites, called " sporozoites ", probably remain in the skin, but others travel in the bloodstream to the liver , where they invade hepatocytes . They grow and divide in the liver for 2–10 days, with each infected hepatocyte eventually harboring up to 40,000 parasites. The infected hepatocytes break down, releasing these invasive Plasmodium cells, called " merozoites ", into
1057-462: A child under five died of malaria in 2021, and "many of these deaths are preventable and treatable". Malaria is commonly associated with poverty and has a significant negative effect on economic development. In Africa, it is estimated to result in losses of US$ 12 billion a year due to increased healthcare costs, lost ability to work, and adverse effects on tourism. The term malaria originates from Medieval Italian : mala aria 'bad air',
1208-431: A comprehensive academic study entitled "The World's 10 most influential languages". In the article, Weber ranked French as, after English, the second-most influential language of the world, ahead of Spanish. His criteria were the numbers of native speakers, the number of secondary speakers (especially high for French among fellow world languages), the number of countries using the language and their respective populations,
1359-414: A consistent supply of microscopy slides and stains. In places where microscopy is unavailable, malaria is diagnosed with RDTs, rapid antigen tests that detect parasite proteins in a fingerstick blood sample. A variety of RDTs are commercially available, targeting the parasite proteins histidine rich protein 2 (HRP2, detects P. falciparum only), lactate dehydrogenase , or aldolase . The HRP2 test
1510-518: A crack in the ground and dies. The colonists, forewarned of the eruption by Nemo, find shelter on the last remaining piece of the island above sea level. They are rescued by the ship Duncan , which had come to rescue Ayrton, but was redirected by a message Nemo had previously left on Tabor Island. After they return to the United States they form a new colony in Iowa, financed with Nemo's gifts. In
1661-555: A foreign language. Due to the rise of French in Africa, the total French-speaking population worldwide is expected to reach 700 million people in 2050. French is the fastest growing language on the continent (in terms of either official or foreign languages). French is increasingly being spoken as a native language in Francophone Africa, especially in regions like Ivory Coast , Cameroon , Gabon, Madagascar , and
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#17327934472591812-472: A greater likelihood of complications and death. Malaria infection affects the immune responses following vaccination for various diseases. For example, malaria suppresses immune responses to polysaccharide vaccines. A potential solution is to give curative treatment before vaccination in areas where malaria is present. Due to the non-specific nature of malaria symptoms, diagnosis is typically suspected based on symptoms and travel history, then confirmed with
1963-456: A laboratory test showing hemoglobin levels below 8 grams per deciliter of blood. In areas of the world with little to no malaria, the WHO recommends only testing people with possible exposure to malaria (typically travel to a malaria-endemic area) and unexplained fever. In sub-Saharan Africa, testing is low, with only about one in four (28%) of children with a fever receiving medical advice or
2114-488: A laboratory test to detect the presence of the parasite in the blood (parasitological test). In areas where malaria is common, the World Health Organization (WHO) recommends clinicians suspect malaria in any person who reports having fevers, or who has a current temperature above 37.5 °C without any other obvious cause. Malaria should be suspected in children with signs of anemia : pale palms or
2265-534: A large amount of sweat on the surface of the skin. Due to the high levels of lactic acid released from the human body, it has been hypothesized to represent a specific human host-recognition cue for anthropophilic (attracted to humans) mosquitoes. Pungent foot odor Most studies use human odors as stimuli to attract host seeking mosquitoes and have reported a strong and significant attractive effect. The studies have found human odor samples very effective in attracting mosquitoes. Foot odors have been demonstrated to have
2416-636: A less pronounced and almost continuous fever. Symptoms typically begin 10–15 days after the initial mosquito bite, but can occur as late as several months after infection with some P. vivax strains. Travellers taking preventative malaria medications may develop symptoms once they stop taking the drugs. Severe malaria is usually caused by P. falciparum (often referred to as falciparum malaria). Symptoms of falciparum malaria arise 9–30 days after infection. Individuals with cerebral malaria frequently exhibit neurological symptoms, including abnormal posturing , nystagmus , conjugate gaze palsy (failure of
2567-487: A memoir by French shipwreck survivor François Édouard Raynal , has additional appendices by French scholar Christiane Mortelier who presents a case for the influence of Raynal's book on Verne's The Mysterious Island . The Grafton was wrecked near New Zealand on the Auckland Islands on 3 January 1864, where the crew of five survived for 19 months before obtaining rescue. Wrecked On A Reef , Raynal's memoir of
2718-435: A non-invasive way to detect malarial infections. In addition, these volatile compounds were heavily detected by mosquito antennae as an attractant, making the children more vulnerable to the bite of the mosquitos. Fatty acids Fatty acids have been identified as an attractive compound for mosquitoes, they are typically found in volatile emissions from the skin. These fatty acids that produce body odor profiles originate from
2869-509: A part of miasma theory ; the disease was formerly called ague or marsh fever due to its association with swamps and marshland. The term appeared in English at least as early as 1768. Malaria was once common in most of Europe and North America, where it is no longer endemic, though imported cases do occur. The scientific study of malaria is called malariology. Adults with malaria tend to experience chills and fever—classically in periodic intense bouts lasting around six hours, followed by
3020-705: A period of prosperity and prominence among European nations. Richelieu established the Académie française to protect the French language. By the early 1800s, Parisian French had become the primary language of the aristocracy in France. Near the beginning of the 19th century, the French government began to pursue policies with the end goal of eradicating the many minorities and regional languages ( patois ) spoken in France. This began in 1794 with Henri Grégoire 's "Report on
3171-530: A period of sweating and fever relief—as well as headache, fatigue, abdominal discomfort, and muscle pain . Children tend to have more general symptoms: fever, cough, vomiting, and diarrhea. Initial manifestations of the disease—common to all malaria species—are similar to flu-like symptoms , and can resemble other conditions such as sepsis , gastroenteritis , and viral diseases . The presentation may include headache , fever , shivering , joint pain , vomiting , hemolytic anemia , jaundice , hemoglobin in
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#17327934472593322-575: A postdoctoral scholar at the University of California, Berkeley studying the structural basis of membrane manipulation and cell-cell fusion by bacterial pathogens, discusses studies that determine how odor profiles can be used to diagnose the disease. Within the study, samples of volatile compounds from around 400 children within schools in Western Kenya were collected - to identify asymptomatic infections. These biomarkers have been established as
3473-635: A rapid diagnostic test in 2021. There was a 10-percentage point gap in testing between the richest and the poorest children (33% vs 23%). Additionally, a greater proportion of children in Eastern and Southern Africa (36%) were tested than in West and Central Africa (21%). According to UNICEF, 61% of children with a fever were taken for advice or treatment from a health facility or provider in 2021. Disparities are also observed by wealth, with an 18 percentage point difference in care-seeking behaviour between children in
3624-494: A relic of the old nominal case system of Latin longer than most other Romance languages (with the notable exception of Romanian which still currently maintains a case distinction), differentiating between an oblique case and a nominative case. The phonology was characterized by heavy syllabic stress, which led to the emergence of various complicated diphthongs such as -eau which would later be leveled to monophthongs. The earliest evidence of what became Old French can be seen in
3775-683: A result of French and Belgian colonialism from the 16th century onward, French was introduced to new territories in the Americas, Africa, and Asia. French has a long history as an international language of literature and scientific standards and is a primary or second language of many international organisations including the United Nations , the European Union, the North Atlantic Treaty Organization ,
3926-540: A sawmill works. In the 20th century two more abridged translations appeared: the Fitzroy Edition (Associated Booksellers, 1959) abridged by I. O. Evans (90,000 words) and Mysterious Island (Bantam, 1970) abridged by Lowell Bair (90,000 words). Except for the Complete and Unabridged Classics Series CL77 published in 1965 (Airmont Publishing Company, Inc), no other unabridged translations appeared until 2001 when
4077-466: A short time, and a "thin film" of blood, allowing them to clearly see individual parasites and identify the infecting Plasmodium species. Under typical field laboratory conditions, a microscopist can detect parasites when there are at least 100 parasites per microliter of blood, which is around the lower range of symptomatic infection. Microscopic diagnosis is relatively resource intensive, requiring trained personnel, specific equipment, electricity, and
4228-595: A small proportion of public expenditure on health. In contrast, a similar programme in Tanzania would cost an estimated one-fifth of the public health budget. In 2021, the World Health Organization confirmed that China has eliminated malaria. In 2023, the World Health Organization confirmed that Azerbaijan , Tajikistan , and Belize have eliminated malaria. In areas where malaria is common, children under five years old often have anaemia , which
4379-547: A variant of Canadian French , is spoken in parts of New England . Missouri French was historically spoken in Missouri and Illinois (formerly known as Upper Louisiana ), but is nearly extinct today. French also survived in isolated pockets along the Gulf Coast of what was previously French Lower Louisiana , such as Mon Louis Island , Alabama and DeLisle, Mississippi (the latter only being discovered by linguists in
4530-518: A way past the net. Insecticide-treated nets (ITNs) are estimated to be twice as effective as untreated nets and offer greater than 70% protection compared with no net. Between 2000 and 2008, the use of ITNs saved the lives of an estimated 250,000 infants in Sub-Saharan Africa. According to UNICEF, only 36% of households had sufficient ITNs for all household members in 2019. In 2000, 1.7 million (1.8%) African children living in areas of
4681-457: A working language along with English and German ; in some institutions, French is the sole working language (e.g. at the Court of Justice of the European Union ). French is also the 16th most natively spoken language in the world, the sixth most spoken language by total number of speakers , and is among the top five most studied languages worldwide, with about 120 million learners as of 2017. As
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4832-437: Is 95%, and in the French collectivity of Wallis and Futuna , it is 84%. In French Polynesia and to a lesser extent Wallis and Futuna, where oral and written knowledge of the French language has become almost universal (95% and 84% respectively), French increasingly tends to displace the native Polynesian languages as the language most spoken at home. In French Polynesia, the percentage of the population who reported that French
4983-479: Is a feature of blackwater fever , where haemoglobin from lysed red blood cells leaks into the urine. Infection with P. falciparum may result in cerebral malaria, a form of severe malaria that involves encephalopathy . It is associated with retinal whitening, which may be a useful clinical sign in distinguishing malaria from other causes of fever. An enlarged spleen , enlarged liver or both of these , severe headache, low blood sugar , and haemoglobin in
5134-472: Is a widespread second language among the Lebanese people , and is taught in many schools along with Arabic and English. French is used on Lebanese pound banknotes, on road signs, on Lebanese license plates , and on official buildings (alongside Arabic). Today, French and English are secondary languages of Lebanon , with about 40% of the population being Francophone and 40% Anglophone. The use of English
5285-489: Is also a working language in nonprofit organisations such as the Red Cross (alongside English, German, Spanish, Portuguese, Arabic and Russian), Amnesty International (alongside 32 other languages of which English is the most used, followed by Spanish, Portuguese, German, and Italian), Médecins sans Frontières (used alongside English, Spanish, Portuguese and Arabic), and Médecins du Monde (used alongside English). Given
5436-518: Is associated with potentially life-threatening conditions about as often as with a diagnosis of P. falciparum infection. P. vivax proportionally is more common outside Africa. Some cases have been documented of human infections with several species of Plasmodium from higher apes , but except for P. knowlesi —a zoonotic species that causes malaria in macaques —these are mostly of limited public health importance. The Anopheles mosquitos initially get infected by Plasmodium by taking
5587-615: Is called Rahosshor Dip . There is also some significance of an adaptation of Captain Nemo and the Mysterious Island in the first arc of the sixth season of Once Upon a Time . French language French ( français [fʁɑ̃sɛ] or langue française [lɑ̃ɡ fʁɑ̃sɛːz] ) is a Romance language of the Indo-European family . Like all other Romance languages, it descended from
5738-446: Is caused by six Plasmodium species: P. falciparum , P. malariae , P. ovale curtisi , P. ovale wallikeri , P. vivax and P. knowlesi . Among those infected, P. falciparum is the most common species identified (~75%) followed by P. vivax (~20%). Although P. falciparum traditionally accounts for the majority of deaths, recent evidence suggests that P. vivax malaria
5889-465: Is deemed severe when any of the following criteria are present, otherwise it is considered uncomplicated. Cerebral malaria is defined as a severe P. falciparum -malaria presenting with neurological symptoms, including coma (with a Glasgow coma scale less than 11, or a Blantyre coma scale less than 3), or with a coma that lasts longer than 30 minutes after a seizure. Methods used to prevent malaria include medications, mosquito elimination and
6040-652: Is enacted only in New Brunswick, where about one third of the population is Francophone. French is also an official language of all of the territories ( Northwest Territories , Nunavut , and Yukon ). Out of the three, Yukon has the most French speakers, making up just under 4% of the population. Furthermore, while French is not an official language in Ontario , the French Language Services Act ensures that provincial services are available in
6191-563: Is growing in the business and media environment. Out of about 900,000 students, about 500,000 are enrolled in Francophone schools, public or private, in which the teaching of mathematics and scientific subjects is provided in French. Actual usage of French varies depending on the region and social status. One-third of high school students educated in French go on to pursue higher education in English-speaking institutions. English
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6342-531: Is insufficient evidence that mosquito repellents can prevent malaria infection. Insecticide-treated nets (ITNs) and indoor residual spraying (IRS) are effective, have been commonly used to prevent malaria, and their use has contributed significantly to the decrease in malaria in the 21st century. ITNs and IRS may not be sufficient to eliminate the disease, as these interventions depend on how many people use nets, how many gaps in insecticide there are (low coverage areas), if people are not protected when outside of
6493-404: Is known as Old French. The period of Old French spanned between the 8th and 14th centuries. Old French shared many characteristics with Latin. For example, Old French made use of different possible word orders just as Latin did because it had a case system that retained the difference between nominative subjects and oblique non-subjects . The period is marked by a heavy superstrate influence from
6644-451: Is not available. In areas where the disease is common, malaria should be confirmed if possible before treatment is started due to concerns of increasing drug resistance . Resistance among the parasites has developed to several antimalarial medications; for example, chloroquine -resistant P. falciparum has spread to most malarial areas, and resistance to artemisinin has become a problem in some parts of Southeast Asia . The disease
6795-469: Is often considered to be a useful skill by business owners in the United Kingdom; a 2014 study found that 50% of British managers considered French to be a valuable asset for their business, thus ranking French as the most sought-after foreign language there, ahead of German (49%) and Spanish (44%). MIT economist Albert Saiz calculated a 2.3% premium for those who have French as a foreign language in
6946-828: Is one of the official languages of such major international and regional courts, tribunals, and dispute-settlement bodies as the African Court on Human and Peoples' Rights , the Caribbean Court of Justice , the Court of Justice for the Economic Community of West African States , the Inter-American Court of Human Rights , the International Court of Justice , the International Criminal Tribunal for
7097-400: Is relatively invisible to immune surveillance. However, circulating infected blood cells are destroyed in the spleen . To avoid this fate, the P. falciparum parasite displays adhesive proteins on the surface of the infected blood cells, causing the blood cells to stick to the walls of small blood vessels, thereby sequestering the parasite from passage through the general circulation and
7248-534: Is saved by a box of quinine sulfate, which mysteriously appears on the table in Granite House. After Harbert recovers, they attempt to rescue Ayrton and destroy the pirates. They discover Ayrton at the sheepfold, and the pirates dead, without any visible wounds except for a little red spot on each of them. The island is revealed to be Captain Nemo 's hideout, and home port of the Nautilus . Having escaped
7399-449: Is sometimes due to malaria. Giving children with anaemia in these areas preventive antimalarial medication improves red blood cell levels slightly but does not affect the risk of death or need for hospitalisation. Vector control refers to methods used to decrease malaria by reducing the levels of transmission by mosquitoes. For individual protection, the most effective insect repellents are based on DEET or picaridin . However, there
7550-408: Is spread exclusively through bites of infected female Anopheles mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver , where they mature and reproduce. Five species of Plasmodium commonly infect humans. The three species associated with more severe cases are P. falciparum (which is responsible for
7701-639: Is taught in universities around the world, and is one of the world's most influential languages because of its wide use in the worlds of journalism, jurisprudence , education, and diplomacy. In diplomacy, French is one of the six official languages of the United Nations (and one of the UN Secretariat 's only two working languages ), one of twenty official and three procedural languages of the European Union , an official language of NATO ,
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#17327934472597852-553: Is the language of business and communication, with French being an element of social distinction, chosen for its emotional value. French is an official language of the Pacific Island nation of Vanuatu , where 31% of the population was estimated to speak it in 2023. In the French special collectivity of New Caledonia , 97% of the population can speak, read and write French while in French Polynesia this figure
8003-483: Is the native language of about 23% of the Swiss population, and is spoken by 50% of the population. Along with Luxembourgish and German, French is one of the three official languages of Luxembourg , where it is generally the preferred language of business as well as of the different public administrations. It is also the official language of Monaco . At a regional level, French is acknowledged as an official language in
8154-492: Is the second-most spoken language (after English) in the states of Maine and New Hampshire . In Louisiana , it is tied with Spanish for second-most spoken if Louisiana French and all creoles such as Haitian are included. French is the third most spoken language (after English and Spanish) in the states of Connecticut , Rhode Island , and New Hampshire . Louisiana is home to many distinct French dialects, collectively known as Louisiana French . New England French , essentially
8305-424: Is the sole official language in the province of Quebec , where some 80% of the population speak it as a native language and 95% are capable of conducting a conversation in it. Quebec is also home to the city of Montreal , which is the world's fourth-largest French-speaking city, by number of first language speakers. New Brunswick and Manitoba are the only officially bilingual provinces, though full bilingualism
8456-425: Is typical) to several years. After a period of dormancy, they reactivate and produce merozoites. Hypnozoites are responsible for long incubation and late relapses in P. vivax infections, although their existence in P. ovale is uncertain. The parasite is relatively protected from attack by the body's immune system because for most of its human life cycle it resides within the liver and blood cells and
8607-413: Is typically attributed to treatment failure. People may develop some immunity when exposed to frequent infections. Malaria infection develops via two phases: one that involves the liver (exoerythrocytic phase), and one that involves red blood cells, or erythrocytes (erythrocytic phase). When an infected mosquito pierces a person's skin to take a blood meal, sporozoites in the mosquito's saliva enter
8758-765: Is widely used in Africa, where P. falciparum predominates. However, since HRP2 persists in the blood for up to five weeks after an infection is treated, an HRP2 test sometimes cannot distinguish whether someone currently has malaria or previously had it. Additionally, some P. falciparum parasites in the Amazon region lack the HRP2 gene, complicating detection. RDTs are fast and easily deployed to places without full diagnostic laboratories. However they give considerably less information than microscopy, and sometimes vary in quality from producer to producer and lot to lot. Serological tests to detect antibodies against Plasmodium from
8909-567: Is widespread in the tropical and subtropical regions that exist in a broad band around the equator . This includes much of sub-Saharan Africa , Asia , and Latin America . In 2022, some 249 million cases of malaria worldwide resulted in an estimated 608,000 deaths, with 80 percent being five years old or less. Around 95% of the cases and deaths occurred in sub-Saharan Africa. Rates of disease decreased from 2010 to 2014, but increased from 2015 to 2021. According to UNICEF, nearly every minute,
9060-764: The Aosta Valley region of Italy where it is the first language of approximately 50% of the population, while French dialects remain spoken by minorities on the Channel Islands . It is also spoken in Andorra and is the main language after Catalan in El Pas de la Casa . The language is taught as the primary second language in the German state of Saarland , with French being taught from pre-school and over 43% of citizens being able to speak French. The majority of
9211-609: The Democratic Republic of Congo . There is not a single African French , but multiple forms that diverged through contact with various indigenous African languages . Sub-Saharan Africa is the region where the French language is most likely to expand, because of the expansion of education and rapid population growth. It is also where the language has evolved the most in recent years. Some vernacular forms of French in Africa can be difficult to understand for French speakers from other countries, but written forms of
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#17327934472599362-517: The Democratic Republic of the Congo . In some North African countries, though not having official status, it is also a first language among some upper classes of the population alongside indigenous languages, but only a second one among the general population. In 2015, approximately 40% of the Francophone population (including L2 and partial speakers) lived in Europe, 36% in sub-Saharan Africa and
9513-533: The European Union , French was the dominant language within all institutions until the 1990s. After several enlargements of the EU (1995, 2004), French significantly lost ground in favour of English, which is more widely spoken and taught in most EU countries. French currently remains one of the three working languages, or "procedural languages", of the EU, along with English and German. It is the second-most widely used language within EU institutions after English, but remains
9664-559: The Francien dialect is one that not only continued but also thrived during the Middle French period (14th–17th centuries). Modern French grew out of this Francien dialect. Grammatically, during the period of Middle French, noun declensions were lost and there began to be standardized rules. Robert Estienne published the first Latin-French dictionary, which included information about phonetics, etymology, and grammar. Politically,
9815-877: The International Olympic Committee , the Council of Europe , the Organisation for Economic Co-operation and Development , Organization of American States (alongside Spanish, Portuguese and English), the Eurovision Song Contest , one of eighteen official languages of the European Space Agency , World Trade Organization and the least used of the three official languages in the North American Free Trade Agreement countries. It
9966-626: The Oaths of Strasbourg and the Sequence of Saint Eulalia , while Old French literature began to be produced in the eleventh century, with major early works often focusing on the lives of saints (such as the Vie de Saint Alexis ), or wars and royal courts, notably including the Chanson de Roland , epic cycles focused on King Arthur and his court , as well as a cycle focused on William of Orange . It
10117-713: The Vulgar Latin of the Roman Empire . French evolved from Gallo-Romance , the Latin spoken in Gaul , and more specifically in Northern Gaul. Its closest relatives are the other langues d'oïl —languages historically spoken in northern France and in southern Belgium, which French ( Francien ) largely supplanted. French was also influenced by native Celtic languages of Northern Roman Gaul like Gallia Belgica and by
10268-775: The World Trade Organization , the International Olympic Committee , the General Conference on Weights and Measures , and the International Committee of the Red Cross . French is a Romance language (meaning that it is descended primarily from Vulgar Latin ) that evolved out of the Gallo-Romance dialects spoken in northern France. The language's early forms include Old French and Middle French . Due to Roman rule, Latin
10419-411: The bone marrow for 11 days, then return to the blood circulation to await uptake by the bite of another mosquito. Once inside a mosquito, the gametocytes undergo sexual reproduction, and eventually form daughter sporozoites that migrate to the mosquito's salivary glands to be injected into a new host when the mosquito bites. The liver infection causes no symptoms; all symptoms of malaria result from
10570-539: The maelstrom at the end of Twenty Thousand Leagues Under the Seas , the Nautilus sailed the oceans of the world until all its crew except Nemo had died. Now an old man, Nemo returned the Nautilus to its secret port within Lincoln Island. Nemo had been the mysterious benefactor of the settlers, providing them with the box of equipment, sending the message revealing Ayrton, planting the torpedo that destroyed
10721-491: The polymerase chain reaction to detect the parasite's DNA have been developed, but they are not widely used in areas where malaria is common, due to their cost and complexity. The risk of disease can be reduced by preventing mosquito bites through the use of mosquito nets and insect repellents or with mosquito-control measures such as spraying insecticides and draining standing water . Several medications are available to prevent malaria for travellers in areas where
10872-626: The provinces of Quebec, Ontario, and New Brunswick); Belgium ( Wallonia and the Brussels-Capital Region ); western Switzerland (specifically the cantons forming the Romandy region); parts of Luxembourg; parts of the United States (the states of Louisiana, Maine, New Hampshire, and Vermont); Monaco; the Aosta Valley region of Italy; and various communities elsewhere. French is estimated to have about 310 million speakers, of which about 80 million are native speakers. According to
11023-523: The "colonists" endure bad weather and domesticate an orangutan , Jupiter, abbreviated to Jup (or Joop, in Jordan Stump's translation). There is a mystery on the island in the form of an unseen deus ex machina , responsible for Cyrus' survival after falling from the balloon, the mysterious rescue of Top from a dugong , the appearance of a box of equipment (guns and ammunition, tools, etc.), and other seemingly inexplicable occurrences. The group finds
11174-427: The ( Germanic ) Frankish language of the post-Roman Frankish invaders. Today, owing to the French colonial empire , there are numerous French-based creole languages , most notably Haitian Creole . A French-speaking person or nation may be referred to as Francophone in both English and French. French is an official language in 27 countries , as well as one of the most geographically widespread languages in
11325-506: The 1990s) but these varieties are severely endangered or presumed extinct. French is one of two official languages in Haiti alongside Haitian Creole . It is the principal language of education, administration, business, and public signage and is spoken by all educated Haitians. It is also used for ceremonial events such as weddings, graduations, and church masses. The vast majority of the population speaks Haitian Creole as their first language;
11476-718: The 20th century, when it was replaced by English as the United States became the dominant global power following the Second World War . Stanley Meisler of the Los Angeles Times said that the fact that the Treaty of Versailles was written in English as well as French was the "first diplomatic blow" against the language. During the Grand Siècle (17th century), France, under the rule of powerful leaders such as Cardinal Richelieu and Louis XIV , enjoyed
11627-703: The Canadian capital, is also effectively bilingual, as it has a large population of federal government workers, who are required to offer services in both French and English, and is just across the river from the Quebecois city of Gatineau . According to the United States Census Bureau (2011), French is the fourth most spoken language in the United States after English, Spanish, and Chinese, when all forms of French are considered together and all dialects of Chinese are similarly combined. French
11778-917: The Caribbean that are collectively referred to as the French West Indies , namely Guadeloupe , Saint Barthélemy , Saint Martin , and Martinique . French is the official language of both French Guiana on the South American continent, and of Saint Pierre and Miquelon , an archipelago off the coast of Newfoundland in North America. French was the official language of the colony of French Indochina , comprising modern-day Vietnam , Laos , and Cambodia . It continues to be an administrative language in Laos and Cambodia, although its influence has waned in recent decades. In colonial Vietnam,
11929-538: The Empire, this local elite had been slowly abandoning Gaulish entirely, but the rural and lower class populations remained Gaulish speakers who could sometimes also speak Latin or Greek. The final language shift from Gaulish to Vulgar Latin among rural and lower class populations occurred later, when both they and the incoming Frankish ruler/military class adopted the Gallo-Roman Vulgar Latin speech of
12080-441: The English plates of Sampson Low. The purported translator, W. H. G. Kingston , was a famous author of boys' adventure and sailing stories who had fallen on hard times in the 1870s due to business failures, and so he hired out to Sampson Low as the translator for these volumes. However, it is now known that the translator of Mysterious Island and his other Verne novels was actually his wife, Agnes Kinloch Kingston, who had studied on
12231-484: The Germanic Frankish language , which non-exhaustively included the use in upper-class speech and higher registers of V2 word order , a large percentage of the vocabulary (now at around 15% of modern French vocabulary ) including the impersonal singular pronoun on (a calque of Germanic man ), and the name of the language itself. Up until its later stages, Old French , alongside Old Occitan , maintained
12382-643: The Indian Ocean, 15% in North Africa and the Middle East, 8% in the Americas, and 1% in Asia and Oceania. French is the second most widely spoken mother tongue in the European Union . Of Europeans who speak other languages natively, approximately one-fifth are able to speak French as a second language. French is the second most taught foreign language in the EU. All institutions of the EU use French as
12533-451: The OIF, approximately 321 million people worldwide are "able to speak the language" as of 2022, without specifying the criteria for this estimation or whom it encompasses. In Francophone Africa, it is spoken mainly as a second language. However it has also become a native language in a number of urban areas, especially in regions like Ivory Coast , Cameroon , Gabon, Madagascar , and
12684-851: The Seas , which begins in 1866, while The Mysterious Island begins during the American Civil War, yet is supposed to happen 16 years after Twenty Thousand Leagues . During the American Civil War , five Northern prisoners of war escape during the Siege of Richmond, Virginia , by hijacking a hydrogen-filled observation balloon. The escapees are Cyrus Smith , a railroad engineer in the Union army (named Cyrus Harding in Kingston 's translation); his ex-slave and loyal follower Neb (short for Nebuchadnezzar ); Bonadventure Pencroff ,
12835-632: The United States the first English printing began in Scribner's Monthly , April 1874, as a serial. In September 1875 Sampson Low, Marston Low, and Searle published the first British edition of Mysterious Island in three volumes entitled Dropped from the Clouds , The Abandoned , and The Secret of the Island (195,000 words). In November 1875 Scribner's published the American edition of these volumes from
12986-405: The absence of Duffy antigens on red blood cells. The impact of sickle cell trait on malaria immunity illustrates some evolutionary trade-offs that have occurred because of endemic malaria. Sickle cell trait causes a change in the haemoglobin molecule in the blood. Normally, red blood cells have a very flexible, biconcave shape that allows them to move through narrow capillaries ; however, when
13137-418: The blood have been developed, but are not used for malaria diagnosis due to their relatively poor sensitivity and specificity. Highly sensitive nucleic acid amplification tests have been developed, but are not used clinically due to their relatively high cost, and poor specificity for active infections. Malaria is classified into either "severe" or "uncomplicated" by the World Health Organization (WHO). It
13288-430: The bloodstream and migrate to the liver where they infect hepatocytes, multiplying asexually and asymptomatically for a period of 8–30 days. After a potential dormant period in the liver, these organisms differentiate to yield thousands of merozoites, which, following rupture of their host cells, escape into the blood and infect red blood cells to begin the erythrocytic stage of the life cycle. The parasite escapes from
13439-540: The bloodstream. In the blood, the merozoites rapidly invade individual red blood cells , replicating over 24–72 hours to form 16–32 new merozoites. The infected red blood cell lyses, and the new merozoites infect new red blood cells, resulting in a cycle that continuously amplifies the number of parasites in an infected person. Over rounds of this infection cycle, a small portion of parasites do not replicate, but instead develop into early sexual stage parasites called male and female " gametocytes ". These gametocytes develop in
13590-408: The brain, they contribute to coma . In the placenta they contribute to low birthweight and preterm labor, and increase the risk of abortion and stillbirth. The destruction of red blood cells during infection often results in anemia, exacerbated by reduced production of new red blood cells during infection. Only female mosquitoes feed on blood; male mosquitoes feed on plant nectar and do not transmit
13741-462: The building of the Nautilus and adopted the new name of "Captain Nemo". Before he dies, Nemo gives them a box of diamonds and pearls as a keepsake. Nemo's final words are "God and my country!" ("Independence!", in Verne's original manuscript). The Nautilus is scuttled and serves as Captain Nemo's tomb. Afterward, the island's central volcano erupts, destroying the island. Jup the orangutan falls into
13892-434: The cause, recurrence can be classified as either recrudescence , relapse , or reinfection. Recrudescence is when symptoms return after a symptom-free period due to failure to remove blood-stage parasites by adequate treatment. Relapse is when symptoms reappear after the parasites have been eliminated from the blood but have persisted as dormant hypnozoites in liver cells. Relapse commonly occurs between 8 and 24 weeks after
14043-451: The continent in her youth. The Kingston translation changes the names of the hero from "Smith" to "Harding"; "Smith" is a very common name in the UK and would have been associated, at that time, with the lower classes. In addition many technical passages were abridged or omitted and the anti-imperialist sentiments of the dying Captain Nemo were purged so as not to offend English readers. This became
14194-668: The country near French-speaking Quebec, however, it is the foreign language more commonly taught. Vowel phonemes in French Malaria Malaria is a mosquito-borne infectious disease that affects vertebrates and Anopheles mosquitoes. Human malaria causes symptoms that typically include fever , fatigue , vomiting , and headaches . In severe cases, it can cause jaundice , seizures , coma , or death . Symptoms usually begin 10 to 15 days after being bitten by an infected Anopheles mosquito . If not properly treated, people may have recurrences of
14345-519: The demographic prospects of the French-speaking nations of Africa, researcher Pascal-Emmanuel Gobry wrote in 2014 that French "could be the language of the future". However, some African countries such as Algeria intermittently attempted to eradicate the use of French, and as of 2024 it was removed as an official language in Mali and Burkina Faso . Significant as a judicial language, French
14496-521: The development of respiratory distress , which occurs in up to 25% of adults and 40% of children with severe P. falciparum malaria. Possible causes include respiratory compensation of metabolic acidosis , noncardiogenic pulmonary oedema , concomitant pneumonia , and severe anaemia . Although rare in young children with severe malaria, acute respiratory distress syndrome occurs in 5–25% of adults and up to 29% of pregnant women. Coinfection of HIV with malaria increases mortality. Kidney failure
14647-509: The disease in the long run, but the initial costs required are out of reach of many of the world's poorest people. There is a wide difference in the costs of control (i.e. maintenance of low endemicity) and elimination programs between countries. For example, in China—whose government in 2010 announced a strategy to pursue malaria elimination in the Chinese provinces —the required investment is
14798-578: The disease is common. Occasional doses of the combination medication sulfadoxine/pyrimethamine are recommended in infants and after the first trimester of pregnancy in areas with high rates of malaria. As of 2023, two malaria vaccines have been endorsed by the World Health Organization . The recommended treatment for malaria is a combination of antimalarial medications that includes artemisinin . The second medication may be either mefloquine , lumefantrine , or sulfadoxine/pyrimethamine. Quinine , along with doxycycline , may be used if artemisinin
14949-475: The disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquito vector is itself harmed by Plasmodium infections, causing reduced lifespan. Human malaria is caused by single-celled microorganisms of the Plasmodium group. It
15100-462: The disease. Females of the mosquito genus Anopheles prefer to feed at night. They usually start searching for a meal at dusk, and continue through the night until they succeed. However, in Africa, due to the extensive use of bed nets, they began to bite earlier, before bed-net time. Malaria parasites can also be transmitted by blood transfusions , although this is rare. Symptoms of malaria can recur after varying symptom-free periods. Depending upon
15251-448: The economic power of the countries using the language, the number of major areas in which the language is used, and the linguistic prestige associated with the mastery of the language (Weber highlighted that French in particular enjoys considerable linguistic prestige). In a 2008 reassessment of his article, Weber concluded that his findings were still correct since "the situation among the top ten remains unchanged." Knowledge of French
15402-594: The elites primarily spoke French, while many servants who worked in French households spoke a French pidgin known as " Tây Bồi " (now extinct). After French rule ended, South Vietnam continued to use French in administration, education, and trade. However, since the Fall of Saigon and the opening of a unified Vietnam's economy, French has gradually been effectively displaced as the first foreign language of choice by English in Vietnam. Nevertheless, it continues to be taught as
15553-494: The eyes to turn together in the same direction), opisthotonus , seizures , or coma . Diagnosis based on skin odor profiles Humans emanate a large range of smells. Studies have been conducted on how to detect human malaria infections through volatile compounds from the skin - suggesting that volatile biomarkers may be a reliable source for the detection of infection, including those asymptomatic. Using skin body odor profiles can be efficient in diagnosing global populations, and
15704-516: The first government authority to adopt Modern French as official was the Aosta Valley in 1536, while the Ordinance of Villers-Cotterêts (1539) named French the language of law in the Kingdom of France . During the 17th century, French replaced Latin as the most important language of diplomacy and international relations ( lingua franca ). It retained this role until approximately the middle of
15855-915: The former Yugoslavia , International Criminal Tribunal for Rwanda , the International Tribunal for the Law of the Sea the International Criminal Court and the World Trade Organization Appellate Body . It is the sole internal working language of the Court of Justice of the European Union , and makes with English the European Court of Human Rights 's two working languages. In 1997, George Weber published, in Language Today ,
16006-442: The frequency with which malaria parasites complete their life cycle in the cell. Individuals who are homozygous (with two copies of the abnormal haemoglobin beta allele ) have sickle-cell anaemia , while those who are heterozygous (with one abnormal allele and one normal allele) experience resistance to malaria without severe anaemia. Although the shorter life expectancy for those with the homozygous condition would tend to disfavour
16157-829: The gender of the corresponding word in Gaulish. The estimated number of French words that can be attributed to Gaulish is placed at 154 by the Petit Robert , which is often viewed as representing standardized French, while if non-standard dialects are included, the number increases to 240. Known Gaulish loans are skewed toward certain semantic fields, such as plant life ( chêne , bille , etc.), animals ( mouton , cheval , etc.), nature ( boue , etc.), domestic activities (ex. berceau ), farming and rural units of measure ( arpent , lieue , borne , boisseau ), weapons, and products traded regionally rather than further afield. This semantic distribution has been attributed to peasants being
16308-399: The highest attractiveness to anthropophilic mosquitoes. Some of these studies have included traps that had been baited with nylon socks previously worn by human participants and were deemed efficient in catching adult mosquitos. Foot odors have high numbers of volatile compounds, which in turn elicit an olfactory response from mosquitoes. Malaria has several serious complications , including
16459-429: The home, and an increase in mosquitoes that are resistant to insecticides. Modifications to people's houses to prevent mosquito exposure may be an important long term prevention measure. Mosquito nets help keep mosquitoes away from people and reduce infection rates and transmission of malaria. Nets are not a perfect barrier and are often treated with an insecticide designed to kill the mosquito before it has time to find
16610-500: The illustrated version of Sidney Kravitz appeared (Wesleyan University Press) almost simultaneously with the new translation of Jordan Stump published by Random House Modern Library (2001). Kravitz also translated Shipwrecked Family: Marooned With Uncle Robinson , published by the North American Jules Verne Society and BearManor Fiction in 2011. The 2003 English edition of Wrecked On A Reef (1869),
16761-418: The incident, was very popular at the time of publication, being translated into multiple languages. According to Mortelier, Verne read Raynal's account and loosely based his novel on the true life story of Grafton shipwreck, survival, privation, and ultimate rescue. The novel has been translated into Marathi by B. R. Bhagwat titled 'निर्जन बेटावरचे धाडसी वीर', which roughly translates as "Brave Fighters on
16912-423: The infection of red blood cells. Symptoms develop once there are more than around 100,000 parasites per milliliter of blood. Many of the symptoms associated with severe malaria are caused by the tendency of P. falciparum to bind to blood vessel walls, resulting in damage to the affected vessels and surrounding tissue. Parasites sequestered in the blood vessels of the lung contribute to respiratory failure . In
17063-502: The initial symptoms and is often seen in P. vivax and P. ovale infections. P. vivax malaria cases in temperate areas often involve overwintering by hypnozoites, with relapses beginning the year after the mosquito bite. Reinfection means that parasites were eliminated from the entire body but new parasites were then introduced. Reinfection cannot readily be distinguished from relapse and recrudescence, although recurrence of infection within two weeks of treatment ending
17214-407: The knowledge of the brilliant engineer Smith, the five are able to sustain themselves on the island, producing fire, pottery, bricks, nitroglycerin , iron, an electric telegraph , a cave home inside a stony cliff called "Granite House", and even a seaworthy ship, which they name the "Bonadventure". They start to think of themselves as colonists rather than castaways. During their stay on the island,
17365-454: The language are very closely related to those of the rest of the French-speaking world. French is the second most commonly spoken language in Canada and one of two federal official languages alongside English. As of the 2021 Canadian census , it was the native language of 7.7 million people (21% of the population) and the second language of 2.9 million (8% of the population). French
17516-479: The language, although it has now given way to Tamil and English. A former French mandate , Lebanon designates Arabic as the sole official language, while a special law regulates cases when French can be publicly used. Article 11 of Lebanon's Constitution states that "Arabic is the official national language. A law determines the cases in which the French language is to be used". The French language in Lebanon
17667-612: The language. The Act applies to areas of the province where there are significant Francophone communities, namely Eastern Ontario and Northern Ontario . Elsewhere, sizable French-speaking minorities are found in southern Manitoba, Nova Scotia , Prince Edward Island and the Port au Port Peninsula in Newfoundland and Labrador, where the unique Newfoundland French dialect was historically spoken. Smaller pockets of French speakers exist in all other provinces. The Ontarian city of Ottawa ,
17818-479: The last to hold onto Gaulish. The beginning of French in Gaul was greatly influenced by Germanic invasions into the country. These invasions had the greatest impact on the northern part of the country and on the language there. A language divide began to grow across the country. The population in the north spoke langue d'oïl while the population in the south spoke langue d'oc . Langue d'oïl grew into what
17969-634: The liver undetected by wrapping itself in the cell membrane of the infected host liver cell. Within the red blood cells, the parasites multiply further, again asexually, periodically breaking out of their host cells to invade fresh red blood cells. Several such amplification cycles occur. Thus, classical descriptions of waves of fever arise from simultaneous waves of merozoites escaping and infecting red blood cells. Some P. vivax sporozoites do not immediately develop into exoerythrocytic-phase merozoites, but instead, produce hypnozoites that remain dormant for periods ranging from several months (7–10 months
18120-431: The metabolism of glycerol, lactic acid, amino acids, and lipids - through the action of bacteria found within the skin. They create a “chemical signature” for the mosquitoes to locate a potential host, humans in particular. Lactic acid Lactic acid, a naturally produced levorotatory isomer, has been titled an attractant of mosquitoes for a long time. Lactic acid is predominantly produced by eccrine-sweat glands, creating
18271-504: The modified haemoglobin S molecules are exposed to low amounts of oxygen, or crowd together due to dehydration, they can stick together forming strands that cause the cell to distort into a curved sickle shape. In these strands, the molecule is not as effective in taking or releasing oxygen, and the cell is not flexible enough to circulate freely. In the early stages of malaria, the parasite can cause infected red cells to sickle, and so they are removed from circulation sooner. This reduces
18422-420: The necessity and means to annihilate the patois and to universalize the use of the French language". When public education was made compulsory , only French was taught and the use of any other ( patois ) language was punished. The goals of the public school system were made especially clear to the French-speaking teachers sent to teach students in regions such as Occitania and Brittany . Instructions given by
18573-451: The novel, rejected by Verne's publisher and wholly reconceived before publication, was titled Shipwrecked Family: Marooned with Uncle Robinson , indicating the influence of the novels Robinson Crusoe and The Swiss Family Robinson . Verne developed a similar theme in his novel, Godfrey Morgan (French: L'École des Robinsons , 1882). The chronology of The Mysterious Island is incompatible with that of Twenty Thousand Leagues Under
18724-534: The other main foreign language in the Vietnamese educational system and is regarded as a cultural language. All three countries are full members of La Francophonie (OIF). French was the official language of French India , consisting of the geographically separate enclaves referred to as Puducherry . It continued to be an official language of the territory even after its cession to India in 1956 until 1965. A small number of older locals still retain knowledge of
18875-514: The parasite eventually disappears from that area, as happened in North America, Europe, and parts of the Middle East. However, unless the parasite is eliminated from the whole world, it could re-establish if conditions revert to a combination that favors the parasite's reproduction. Furthermore, the cost per person of eliminating anopheles mosquitoes rises with decreasing population density, making it economically unfeasible in some areas. Prevention of malaria may be more cost-effective than treatment of
19026-469: The pirate ship, and killing the pirates with an "electric gun". On his death bed, Captain Nemo reveals his true identity as the lost Indian Prince Dakkar, son of a raja of the then-independent territory of Bundelkund and a nephew of the Indian hero Tippu-Sahib . After taking part in the failed Indian Rebellion of 1857 , Prince Dakkar escaped to a desert island with twenty of his compatriots and commenced
19177-471: The preferred language of certain institutions or administrations such as the Court of Justice of the European Union , where it is the sole internal working language, or the Directorate-General for Agriculture . Since 2016, Brexit has rekindled discussions on whether or not French should again hold greater role within the institutions of the European Union. A leading world language , French
19328-456: The prevention of bites. As of 2023, there are two malaria vaccines , approved for use in children by the WHO: RTS,S and R21 . The presence of malaria in an area requires a combination of high human population density, high Anopheles mosquito population density and high rates of transmission from humans to mosquitoes and from mosquitoes to humans. If any of these is lowered sufficiently,
19479-517: The protagonists, the pirate ship is mysteriously destroyed by an explosion. Six of the pirates survive and kidnap Ayrton. When the colonists look for him, the pirates shoot Harbert, seriously injuring him. Harbert survives, narrowly evading death. The colonists at first assume Ayrton has been killed, but later they find evidence that he was not instantly killed, leaving his fate uncertain. When the colonists rashly attempt to return to Granite House before Harbert fully recovers, Harbert contracts malaria but
19630-471: The rest largely speak French as a first language. As a French Creole language , Haitian Creole draws the large majority of its vocabulary from French, with influences from West African languages, as well as several European languages. It is closely related to Louisiana Creole and the creole from the Lesser Antilles . French is the sole official language of all the overseas territories of France in
19781-411: The richest (71%) and the poorest (53%) households. Malaria is usually confirmed by the microscopic examination of blood films or by antigen -based rapid diagnostic tests (RDT). Microscopy—i.e. examining Giemsa -stained blood with a light microscope —is the gold standard for malaria diagnosis. Microscopists typically examine both a "thick film" of blood, allowing them to scan many blood cells in
19932-437: The screening and monitoring of infection to officially eradicate malaria. Research findings have predominantly relied on chemical explanations to explain the differences in attractiveness among humans based on distinct odor profiles. The existence of volatile compounds, like fatty acids, and lactic acid is an essential reason on why some individuals are more appealing to mosquitos than others. Volatile compounds Kanika Khanna,
20083-563: The spleen. The blockage of the microvasculature causes symptoms such as those in placental malaria. Sequestered red blood cells can breach the blood–brain barrier and cause cerebral malaria. Due to the high levels of mortality and morbidity caused by malaria—especially the P. falciparum species—it has placed the greatest selective pressure on the human genome in recent history. Several genetic factors provide some resistance to it including sickle cell trait , thalassaemia traits, glucose-6-phosphate dehydrogenase deficiency , and
20234-491: The standard translation for more than a century. In 1876 the Stephen W. White translation (175,000 words) appeared first in the columns of The Evening Telegraph of Philadelphia and subsequently as an Evening Telegraph Reprint Book. This translation is more faithful to the original story and restores the death scene of Captain Nemo, but there is still condensation and omission of some sections such as Verne's description of how
20385-466: The total number of French speakers will reach approximately 500 million in 2025 and 650 million by 2050, largely due to rapid population growth in sub-Saharan Africa . OIF estimates 700 million French speakers by 2050, 80% of whom will be in Africa. In a study published in March 2014 by Forbes , the investment bank Natixis said that French could become the world's most spoken language by 2050. In
20536-612: The trait's survival, the trait is preserved in malaria-prone regions because of the benefits provided by the heterozygous form. Liver dysfunction as a result of malaria is uncommon and usually only occurs in those with another liver condition such as viral hepatitis or chronic liver disease . The syndrome is sometimes called malarial hepatitis . While it has been considered a rare occurrence, malarial hepatopathy has seen an increase, particularly in Southeast Asia and India. Liver compromise in people with malaria correlates with
20687-679: The two official languages—along with Dutch —of the Brussels-Capital Region , where it is spoken by the majority of the population (approx. 80%), often as their primary language. French is one of the four official languages of Switzerland, along with German, Italian, and Romansh , and is spoken in the western part of Switzerland, called Romandy , of which Geneva is the largest city. The language divisions in Switzerland do not coincide with political subdivisions, and some cantons have bilingual status: for example, cities such as Biel/Bienne and cantons such as Valais , Fribourg and Bern . French
20838-508: The urban intellectual elite. The Gaulish language likely survived into the sixth century in France despite considerable Romanization . Coexisting with Latin, Gaulish helped shape the Vulgar Latin dialects that developed into French contributing loanwords and calques (including oui , the word for "yes"), sound changes shaped by Gaulish influence, and influences in conjugation and word order. Recent computational studies suggest that early gender shifts may have been motivated by
20989-415: The urine with kidney failure may occur. Complications may include spontaneous bleeding, coagulopathy , and shock . Malaria during pregnancy can cause stillbirths , infant mortality , miscarriage , and low birth weight , particularly in P. falciparum infection, but also with P. vivax . Malaria is caused by infection with parasites in the genus Plasmodium . In humans, malaria
21140-424: The urine , retinal damage , and convulsions . The classic symptom of malaria is paroxysm —a cyclical occurrence of sudden coldness followed by shivering and then fever and sweating, occurring every two days ( tertian fever ) in P. vivax and P. ovale infections, and every three days ( quartan fever ) for P. malariae . P. falciparum infection can cause recurrent fever every 36–48 hours, or
21291-485: The use of French in official government publications, public education except in specific cases, and legal contracts; advertisements must bear a translation of foreign words. In Belgium, French is an official language at the federal level along with Dutch and German. At the regional level, French is the sole official language of Wallonia (excluding a part of the East Cantons , which are German-speaking ) and one of
21442-401: The vast majority of malaria deaths), P. vivax , and P. knowlesi (a simian malaria that spills over into thousands of people a year). P. ovale and P. malariae generally cause a milder form of malaria. Malaria is typically diagnosed by the microscopic examination of blood using blood films , or with antigen-based rapid diagnostic tests . Methods that use
21593-536: The workplace. In 2011, Bloomberg Businessweek ranked French the third most useful language for business, after English and Standard Mandarin Chinese . In English-speaking Canada, the United Kingdom, and Ireland, French is the first foreign language taught and in number of pupils is far ahead of other languages. In the United States, French is the second-most commonly taught foreign language in schools and universities, although well behind Spanish. In some areas of
21744-427: The world where malaria is common were protected by an ITN. That number increased to 20.3 million (18.5%) African children using ITNs in 2007, leaving 89.6 million children unprotected and to 68% African children using mosquito nets in 2015. The percentage of children sleeping under ITNs in sub-Saharan Africa increased from less than 40% in 2011 to over 50% in 2021. Most nets are impregnated with pyrethroids ,
21895-402: The world's French-speaking population lives in Africa. According to a 2023 estimate from the Organisation internationale de la Francophonie , an estimated 167 million African people spread across 35 countries and territories can speak French as either a first or a second language . This number does not include the people living in non-Francophone African countries who have learned French as
22046-503: The world, with about 50 countries and territories having it as a de jure or de facto official, administrative, or cultural language. Most of these countries are members of the Organisation internationale de la Francophonie (OIF), the community of 54 member states which share the official use or teaching of French. It is spoken as a first language (in descending order of the number of speakers) in France; Canada (especially in
22197-819: Was during the period of the Crusades in which French became so dominant in the Mediterranean Sea that became a lingua franca ("Frankish language"), and because of increased contact with the Arabs during the Crusades who referred to them as Franj , numerous Arabic loanwords entered French, such as amiral (admiral), alcool (alcohol), coton (cotton) and sirop (syrop), as well as scientific terms such as algébre (algebra), alchimie (alchemy) and zéro (zero). Within Old French many dialects emerged but
22348-400: Was gradually adopted by the inhabitants of Gaul. As the language was learned by the common people, it developed a distinct local character, with grammatical differences from Latin as spoken elsewhere, some of which is attested in graffiti. This local variety evolved into the Gallo-Romance tongues, which include French and its closest relatives, such as Arpitan . The evolution of Latin in Gaul
22499-652: Was known in the Occitan-speaking region as Vergonha . Spoken by 19.71% of the European Union's population, French is the third most widely spoken language in the EU, after English and German and the second-most-widely taught language after English. Under the Constitution of France , French has been the official language of the Republic since 1992, although the Ordinance of Villers-Cotterêts made it mandatory for legal documents in 1539. France mandates
22650-594: Was shaped by its coexistence for over half a millennium beside the native Celtic Gaulish language , which did not go extinct until the late sixth century, long after the fall of the Western Roman Empire . The population remained 90% indigenous in origin; the Romanizing class were the local native elite (not Roman settlers), whose children learned Latin in Roman schools. At the time of the collapse of
22801-570: Was the language they use the most at home rose from 67% at the 2007 census to 74% at the 2017 census. In Wallis and Futuna, the percentage of the population who reported that French was the language they use the most at home rose from 10% at the 2008 census to 13% at the 2018 census. According to a demographic projection led by the Université Laval and the Réseau Démographie de l'Agence universitaire de la Francophonie ,
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