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Linus Pauling

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125-448: Post-docs: Linus Carl Pauling FRS ( / ˈ p ɔː l ɪ ŋ / PAW -ling ; February 28, 1901 – August 19, 1994) was an American chemist , biochemist , chemical engineer , peace activist , author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. New Scientist called him one of the 20 greatest scientists of all time. For his scientific work, Pauling

250-580: A historic district designation. The Memorial Union was designed by OSU alum and renowned Oregon architect, Lee Arden Thomas . It has been recognized as "one of the finest examples of neoclassical architecture in Oregon." In 2016 OSU completed the construction of a 10-acre branch campus in Bend . This campus is called OSU-Cascades and offers students living in Oregon's central region an opportunity to attend select classes closer to their homes. As of 2023,

375-484: A "comprehensive doctoral with medical/veterinary" university. It is one of three such universities in the Pacific Northwest to be classified in this category. In 2006, Carnegie also recognized OSU as having "very high research activity", making it the only university in Oregon to attain these combined classifications. OSU was one of the early members of the federal Space Grant program. Designated in 1991,

500-797: A "limited passport" to attend the conference. His full passport was restored in 1954, shortly before the ceremony in Stockholm where he received his first Nobel Prize. Joining Einstein, Bertrand Russell and eight other leading scientists and intellectuals, he signed the Russell-Einstein Manifesto issued July 9, 1955. He also supported the Mainau Declaration of July 15, 1955, signed by 52 Nobel Prize laureates. In May 1957, working with Washington University in St. Louis professor Barry Commoner , Pauling began to circulate

625-513: A $ 2.06 billion economic footprint. $ 1.93 billion of this total was in the state of Oregon. Corvallis is Oregon's 9th-largest city. It is a relatively small community and many of the local events have a strong connection to the university. OSU has over 400 active student organizations and groups. The campus is only a few hours' driving distance from any number of outdoor recreation opportunities. Several federal and state natural forests and parks are popular student destinations. These include

750-763: A Chair (all of whom are Fellows of the Royal Society ). Members of the 10 Sectional Committees change every three years to mitigate in-group bias . Each Sectional Committee covers different specialist areas including: New Fellows are admitted to the Society at a formal admissions day ceremony held annually in July, when they sign the Charter Book and the Obligation which reads: "We who have hereunto subscribed, do hereby promise, that we will endeavour to promote

875-505: A Molecular Disease " in the journal Science . It was the first proof of a human disease being caused by an abnormal protein, and sickle cell anemia became the first disease understood at the molecular level. (It was not, however, the first demonstration that variant forms of hemoglobin could be distinguished by electrophoresis, which had been shown several years earlier by Maud Menten and collaborators). Using electrophoresis , they demonstrated that individuals with sickle cell disease have

1000-592: A chair/head/director who oversees program coordinators. Each school or department is responsible for academic programs leading to degrees, certificates, options or minors. The OSU Educational Extension is a section for non-students and adult education . The OSU Extension service is an agricultural extension established on July 24, 1911, under the leadership of Vice Provost Ivory W. Lyles (OSU Extension Service Administration). There are OSU Extension offices, Combined Experiment & Oregon Agricultural Experiment Stations , and Branch Experiment Stations located throughout

1125-504: A correct structure for the DNA double helix. Pauling later cited several reasons to explain how he had been misled about the structure of DNA, among them misleading density data and the lack of high quality X-ray diffraction photographs. Pauling described this situation as "the biggest disappointment in his life". During the time Pauling was researching the problem, Rosalind Franklin in England

1250-648: A degree in chemical engineering . He went on to graduate school at the California Institute of Technology (Caltech) in Pasadena, California , under the guidance of Roscoe Dickinson and Richard Tolman . His graduate research involved the use of X-ray diffraction to determine the structure of crystals . He published seven papers on the crystal structure of minerals while he was at Caltech. He received his PhD in physical chemistry and mathematical physics , summa cum laude , in 1925. In 1926, Pauling

1375-447: A direction not always popular with established Caltech chemists. In 1951, Pauling gave a lecture entitled "Molecular Medicine". In the late 1950s, he studied the role of enzymes in brain function, believing that mental illness may be partly caused by enzyme dysfunction. In the 1960s, as part of his interest in the effects of nuclear weapons, he investigated the role of mutations in evolution, proposing with his student Emile Zuckerkandl,

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1500-581: A goal of $ 625 million. Donors exceeded the goal in October 2010 nearly a year ahead of schedule, resulting in a goal increase to $ 850 million. In March 2012, the goal was raised to $ 1 billion. At OSU's annual State of the University address in Portland on January 31, 2014, President Edward J. Ray announced that campaign contributions had passed $ 1 billion, making OSU one of 35 public universities to cross

1625-425: A longitudinal study to measure radioactive strontium -90 in the baby teeth of children across North America. The " Baby Tooth Survey ", published by Louise Reiss , demonstrated conclusively in 1961 that above-ground nuclear testing posed significant public health risks in the form of radioactive fallout spread primarily via milk from cows that had ingested contaminated grass. The Committee for Nuclear Information

1750-689: A means of solving international conflicts." Pauling himself acknowledged his wife Ava's deep involvement in peace work, and regretted that she was not awarded the Nobel Peace Prize with him. Fellow of the Royal Society Fellowship of the Royal Society ( FRS , ForMemRS and HonFRS ) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to

1875-400: A modified form of hemoglobin in their red blood cells , and that individuals with sickle cell trait have both the normal and abnormal forms of hemoglobin. This was the first demonstration causally linking an abnormal protein to a disease, and also the first demonstration that Mendelian inheritance determines the specific physical properties of proteins, not simply their presence or absence –

2000-400: A month (equivalent to US$ 1,500 in 2023), enabling him to continue his studies. In his last two years at school, Pauling became aware of the work of Gilbert N. Lewis and Irving Langmuir on the electronic structure of atoms and their bonding to form molecules . He decided to focus his research on how the physical and chemical properties of substances are related to the structure of

2125-413: A petition among scientists to stop nuclear testing. On January 15, 1958, Pauling and his wife presented a petition to United Nations Secretary General Dag Hammarskjöld calling for an end to the testing of nuclear weapons . It was signed by 11,021 scientists representing fifty countries. In February 1958, Pauling participated in a publicly televised debate with the atomic physicist Edward Teller about

2250-442: A pioneer in the application of quantum theory to the structure of molecules. In 1927, Pauling took a new position as an assistant professor at Caltech in theoretical chemistry . He launched his faculty career with a very productive five years, continuing with his X-ray crystal studies and also performing quantum mechanical calculations on atoms and molecules. He published approximately fifty papers in those five years, and created

2375-564: A possible replacement for human blood plasma in transfusions : polyoxy gelatin (Oxypolygelatin). Other wartime projects with more direct military applications included work on explosives, rocket propellants and the patent for an armor-piercing shell. In October 1948, Pauling, along with Lee A. DuBridge , William A. Fowler , Max Mason , and Bruce H. Sage , was awarded a Presidential Medal for Merit by President Harry S. Truman . The citation credits him for his "imaginative mind", "brilliant success", and "exceptionally meritorious conduct in

2500-454: A resource for K-12 educators and the public. OSU's agriculture, oceanography and marine science students have an opportunity to serve as summer interns at the Newport campus, while post-graduate students participate in a wide array of research programs year-around. A $ 16.5 million project to build a 34,000-square-foot dormitory for OSU's post-graduate students, staff and visiting professionals

2625-418: A stunning personal collection of minerals. The two men planned to mount a joint attack on the nature of the chemical bond: apparently Oppenheimer would supply the mathematics and Pauling would interpret the results. Their relationship soured when Oppenheimer tried to pursue Pauling's wife, Ava Helen. When Pauling was at work, Oppenheimer came to their home and blurted out an invitation to Ava Helen to join him on

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2750-611: A top-10-ranking since 2015. In 2021 College Choice ranked the Ecampus college of liberal arts program the best in the nation. The same faculty teaching on campus also teach many of their programs and courses online through the Oregon State University Ecampus website. Students who pursue an online education at Oregon State earn the same diploma and transcript as on-campus students. In 2017, Oregon State University's Portland headquarters were relocated to

2875-539: A tryst in Mexico. She flatly refused, and reported the incident to Pauling. He immediately cut off his relationship with Oppenheimer. In the summer of 1930, Pauling made another European trip, during which he learned about gas-phase electron diffraction from Herman Francis Mark . After returning, he built an electron diffraction instrument at Caltech with a student of his, Lawrence Olin Brockway , and used it to study

3000-560: A volunteer board of trustees. It holds net assets exceeding $ 1 billion and manages most of the university's composite endowment, valued at more than $ 827 million. In October 2022, the Foundation publicly launched Believe It: The Campaign for OSU, the university’s second comprehensive fundraising and engagement campaign, with a $ 1.75 billion goal for student and faculty support, facilities and equipment and strategic initiatives. Donors have stepped forward with over $ 1 billion in gifts since

3125-413: A way that the protein molecules were tilted from their expected positions. Pauling had formulated a model for the structure of hemoglobin in which atoms were arranged in a helical pattern, and applied this idea to proteins in general. In 1951, based on the structures of amino acids and peptides and the planar nature of the peptide bond , Pauling, Robert Corey and Herman Branson correctly proposed

3250-419: Is a UNESCO International Biosphere Reserve . OSU's Open Source Lab is a nonprofit founded in 2003 and funded in part by corporate sponsors that include Facebook, Google, and IBM. The organization's goal is to advance open source technology by hiring and training students in software development and operations for large-scale coding projects. The lab hosts a number of projects, including contracted work for

3375-600: Is classified by the Carnegie Classification of Institutions of Higher Education as an R1: Doctoral University with very high research activity. Chartered as a land-grant university initially, OSU became one of the four inaugural members of the Sea Grant in 1971. Memberships in the Space Grant and Sun Grant research consortias were awarded in 1991 and 2003, making it one of only three schools in

3500-633: Is co-leading the largest ocean science project in U.S. history. The Ocean Observatories Initiative (OOI) features a fleet of undersea gliders at six sites in the Pacific and Atlantic Oceans with multiple observation platforms. CEOAS is also leading the design and construction of the next class of ocean-faring research vessels for the National Science Foundation , which will be the largest grant or contract ever received by any Oregon university. The first of three planned research vessels,

3625-737: Is confirmed by the Council in April, and a secret ballot of Fellows is held at a meeting in May. A candidate is elected if they secure two-thirds of votes of those Fellows voting. An indicative allocation of 18 Fellowships can be allocated to candidates from Physical Sciences and Biological Sciences; and up to 10 from Applied Sciences, Human Sciences and Joint Physical and Biological Sciences. A further maximum of six can be 'Honorary', 'General' or 'Royal' Fellows. Nominations for Fellowship are peer reviewed by Sectional Committees, each with at least 12 members and

3750-525: Is frequently credited for its significant contribution to supporting the test ban, as is the ground-breaking research conducted by Reiss and the "Baby Tooth Survey". Public pressure and the frightening results of the CNI research led to a moratorium on above-ground nuclear weapons testing, followed by the Partial Test Ban Treaty , signed in 1963 by John F. Kennedy and Nikita Khrushchev . On

3875-510: Is known for relying heavily on outcome-based data to compile their rankings. In 2021, U.S. News & World Report ranked OSU tied for 139th nationally, tied for 71st top public and tied for 58th "most innovative" university in the U.S., and tied for 277th best globally. In its 2021 Global Ranking of Academic Subjects, the Academic Ranking of World Universities (ARWU) ranked Oregon State University's oceanography program 5th in

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4000-746: Is located in McAlexander Fieldhouse, named after General Ulysses G. McAlexander , the former commander of Army ROTC. After the Second World War ended in 1945, a Department of Naval Science was added at Oregon State. Providing officer training for both the US Navy and the US Marine Corps , it became one of the largest in the nation and has earned the unofficial title "Naval Academy of the Northwest." On July 1, 1949,

4125-421: Is nominated by two Fellows of the Royal Society (a proposer and a seconder), who sign a certificate of proposal. Previously, nominations required at least five fellows to support each nomination by the proposer, which was criticised for supposedly establishing an old boy network and elitist gentlemen's club . The certificate of election (see for example ) includes a statement of the principal grounds on which

4250-465: Is the largest university in the state and set a new record for enrollment in 2023. Close to 37,000 students attended the university during the year - the most for any Oregon university on record. For fall 2015, OSU received 14,058 freshman applications; 11,016 were admitted (78.4%) and 3,593 enrolled. Fall of 2022 brought in the largest freshman class the university had seen, with 7,146 new students. The average high school grade point average ( GPA ) of

4375-553: Is under one year). The site is shallower than PacWave South and closer to port. The National Institute of Environmental Health Sciences funds two research centers at OSU. The Environmental Health Sciences Center has been funded since 1969 and the Superfund Research Center has been funded since 2009. OSU administers the H.J. Andrews Experimental Forest , a United States Forest Service facility dedicated to forestry and ecology research. The Andrews Forest

4500-606: Is useful in predicting the nature of bonds between atoms in molecules. In 1936, Pauling was promoted to chairman of the division of chemistry and chemical engineering at Caltech, and to the position of director of the Gates and Crellin Laboratories of Chemistry. He would hold both positions until 1958. Pauling also spent a year in 1948 at the University of Oxford as George Eastman Visiting Professor and Fellow of Balliol. In

4625-658: The Proceedings of the National Academy of Sciences . For nearly three decades, until his death in 1994, Pauling published numerous papers on his spheron cluster model. The basic idea behind Pauling's spheron model is that a nucleus can be viewed as a set of "clusters of nucleons". The basic nucleon clusters include the deuteron [np], helion [pnp], and triton [npn]. Even–even nuclei are described as being composed of clusters of alpha particles , as has often been done for light nuclei. Pauling attempted to derive

4750-948: The Hatfield Marine Science Center and multiple oceanographic research vessels based in Newport . In 2001, OSU's Wave Research Laboratory was designated by the National Science Foundation as a site for tsunami research under the Network for Earthquake Engineering Simulation. The O. H. Hinsdale Wave Research Laboratory is on the edge of the campus and is one of the world's largest and most sophisticated laboratories for education, research and testing in coastal, ocean and related areas. Oregon State University operates two off-shore research test facilities near Newport, Oregon for commercial wave energy technology companies to stress test prototypes. The North and South PacWave Energy Test Facilities are located several miles off

4875-597: The Independent Citizens Committee of the Arts, Sciences and Professions (ICCASP) on atomic weapons ; shortly after, wife Ava and he accepted membership. On January 21, 1946, the group met to discuss academic freedom , during which Pauling said, "There is, of course, always a threat to academic freedom – as there is to the other aspects of the freedom and rights of the individual, in the continued attacks which are made on this freedom, these rights, by

5000-660: The Linux Foundation . Oregon State University is one of the few universities to have ROTC detachments for each branch of the US Military . Oregon State University Army ROTC is a distinguished program and has been taught regularly since 1873. The so-called Beaver Battalion is known as the West Point of the West for producing more commissioned officers than any other non-military school during World War II . It

5125-630: The Nobel Prize in Chemistry in 1954 "for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances". Pauling's book has been considered "chemistry's most influential book of this century and its effective bible". In the 30 years after its first edition was published in 1939, the book was cited more than 16,000 times. Even today, many modern scientific papers and articles in important journals cite this work, more than seventy years after

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5250-601: The US Army Air Corps training branch became a separate officer training unit later known as Aerospace Science. The Oregon State Air Force ROTC draws more freshmen scholarships than any other AFROTC unit in the nation and has had over 1,000 officers commissioned. In 1977, two graduates of the OSU AFROTC became the first women pilots in the Air Force. The Army and Air Force ROTC programs at the university share

5375-435: The alpha helix and beta sheet as the primary structural motifs in protein secondary structure . This work exemplified Pauling's ability to think unconventionally; central to the structure was the unorthodox assumption that one turn of the helix may well contain a non- integer number of amino acid residues; for the alpha helix it is 3.7 amino acid residues per turn. Pauling then proposed that deoxyribonucleic acid (DNA)

5500-415: The electronic structure of atoms and molecules. In Zürich, Pauling was also exposed to one of the first quantum mechanical analyses of bonding in the hydrogen molecule, done by Walter Heitler and Fritz London . Pauling devoted the two years of his European trip to this work and decided to make it the focus of his future research. He became one of the first scientists in the field of quantum chemistry and

5625-503: The molecular structure of a large number of chemical substances. Pauling introduced the concept of electronegativity in 1932. Using the various properties of molecules, such as the energy required to break bonds and the dipole moments of molecules, he established a scale and an associated numerical value for most of the elements  —  the Pauling Electronegativity Scale  —  which

5750-426: The post-nominal letters FRS . Every year, fellows elect up to ten new foreign members. Like fellows, foreign members are elected for life through peer review on the basis of excellence in science. As of 2016 , there are around 165 foreign members, who are entitled to use the post-nominal ForMemRS . Honorary Fellowship is an honorary academic title awarded to candidates who have given distinguished service to

5875-421: The quantum-mechanical wave function for a polar molecule AB is a combination of wave functions for covalent and ionic molecules. Here Pauling's electronegativity concept is particularly useful; the electronegativity difference between a pair of atoms will be the surest predictor of the degree of ionicity of the bond. The third of the topics that Pauling attacked under the overall heading of "the nature of

6000-520: The "agricultural college of the state of Oregon". Acceptance of this grant required the college to comply with the requirements set forth in the Morrill Land-Grant Acts . The school was then authorized to grant Bachelor of Arts , Bachelor of Science and Master of Arts degrees. The first graduating class was in 1870, with Bachelor of Arts degrees. In 1872, the name of the school was changed to Corvallis State Agricultural College. As

6125-471: The Chemistry division of the project. He declined, not wanting to uproot his family. Pauling did, however, work on research for the military. He was a principal investigator on 14 OSRD contracts . The National Defense Research Committee called a meeting on October 3, 1940, wanting an instrument that could reliably measure oxygen content in a mixture of gases, so that they could measure oxygen conditions in submarines and airplanes. In response Pauling designed

6250-629: The Corvallis campus and major work in the liberal arts and related subjects to the University of Oregon in Eugene. This was the first in a series of actions to make the curricula of the two schools separate and distinct." In 1929 the legislative assembly passed the Oregon Unification Bill, which placed Oregon's public colleges under greater oversight of the newly renamed Oregon State Board of Higher Education . A doctorate in education

6375-717: The Corvallis campus, but an increasing number of endeavors are underway at locations throughout the state and abroad. Research facilities beyond the campus include the John L. Fryer Aquatic Animal Health Laboratory in Corvallis, the Seafood Laboratory in Astoria and the Food Innovation Laboratory in Portland . The 2005 Carnegie Classification of Institutions of Higher Education recognized OSU as

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6500-630: The McAlexander Fieldhouse. In 1999, OSU finished a $ 40 million remodeling of the campus library. Known as the Valley Library , the remodeled building was selected by The Library Journal as its 1999 Library of the Year, the first academic library so named. In 2023, the Center for World University Rankings (CWUR) ranked Oregon State University in the top 1.4 percent out of 20,531 degree-granting institutions of higher education worldwide. The CWUR

6625-609: The Pauling oxygen meter, which was developed and manufactured by Arnold O. Beckman, Inc. After the war, Beckman adapted the oxygen analyzers for use in incubators for premature babies. In 1942, Pauling successfully submitted a proposal on "The Chemical Treatment of Protein Solutions in the Attempt to Find a Substitute for Human Serum for Transfusions". His project group, which included Joseph B. Koepfli and Dan H. Campbell, developed

6750-439: The Royal Society has been described by The Guardian as "the equivalent of a lifetime achievement Oscar " with several institutions celebrating their announcement each year. Up to 60 new Fellows (FRS), honorary (HonFRS) and foreign members (ForMemRS) are elected annually in late April or early May, from a pool of around 700 proposed candidates each year. New Fellows can only be nominated by existing Fellows for one of

6875-663: The Society, we shall be free from this Obligation for the future". Since 2014, portraits of Fellows at the admissions ceremony have been published without copyright restrictions in Wikimedia Commons under a more permissive Creative Commons license which allows wider re-use. In addition to the main fellowships of the Royal Society (FRS, ForMemRS & HonFRS), other fellowships are available which are applied for by individuals, rather than through election. These fellowships are research grant awards and holders are known as Royal Society Research Fellows . In addition to

7000-700: The Taani, was launched in May 2023 and will be stationed in Newport, Oregon . OSU also manages nearly 11,250 acres (4,550 ha) of forest land, including the McDonald-Dunn Research Forest. In 1967 the Radiation Center was constructed at the edge of campus, housing a 1.1 MW TRIGA Mark II Research Reactor . The reactor is equipped to utilize high-assay, low-enriched ( HALEU ) uranium zirconium hydride fuel. U.S. News & World Report 's 2008 rankings placed OSU eighth in

7125-612: The actual probability of fallout causing mutations. Later in 1958, Pauling published No more war! , in which he not only called for an end to the testing of nuclear weapons but also an end to war itself. He proposed that a World Peace Research Organization be set up as part of the United Nations to "attack the problem of preserving the peace". Pauling also supported the work of the St. Louis Citizen's Committee for Nuclear Information (CNI). This group, headed by Barry Commoner , Eric Reiss, M. W. Friedlander and John Fowler, organized

7250-466: The additional grant program made Oregon State one of only 13 schools in the United States at that time to serve as a combined Land Grant , Sea Grant and Space Grant university. The university's College of Earth, Ocean and Atmospheric Sciences (CEOAS) operates several laboratories, including the Hatfield Marine Science Center and multiple oceanographic research vessels based in Newport . CEOAS

7375-466: The appropriate orbitals to describe certain unsaturated carbon compounds such as ethylene . Other hybridization schemes are also found in other types of molecules. Another area which he explored was the relationship between ionic bonding , where electrons are transferred between atoms, and covalent bonding , where electrons are shared between atoms on an equal basis. Pauling showed that these were merely extremes, and that for most actual cases of bonding,

7500-458: The atoms of which they are composed, becoming one of the founders of the new science of quantum chemistry. Engineering professor Samuel Graf (1887–1966) selected Pauling to be his teaching assistant in a mechanics and materials course. During the winter of his senior year, Pauling taught a chemistry course for home economics majors. It was in one of these classes that Pauling met his future wife, Ava Helen Miller . In 1922, Pauling graduated with

7625-593: The award of Fellowship (FRS, HonFRS & ForMemRS) and the Research Fellowships described above, several other awards, lectures and medals of the Royal Society are also given. Oregon State University Oregon State University ( OSU ) is a public land-grant research university in Corvallis, Oregon . OSU offers more than 200 undergraduate-degree programs along with a variety of graduate and doctoral degrees through all 11 colleges. It has

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7750-489: The billion-dollar fundraising mark and one of only two organizations in the Pacific Northwest to reach that milestone. The Campaign for OSU concluded on December 31, 2014, with more than $ 1.1 billion from 106,000 donors. The Oregon State University Foundation is a nonprofit organization chartered to raise and administer private funds in support of the university's education, research and outreach, governed by

7875-519: The branch campus stretches across 30 acres in southwest Bend , with options to grow into 90 more acres of OSU-owned land nearby. The latest goal is to attract around 5,000 students per year within the next decade. As of 2023, enrollment was around 1,400 students. Oregon State offers more than 80 degree and certificate programs made up from a selection of over 1,500 online courses in more than 110 subjects. US News & World Report ranks OSU's online Ecampus fourth nationally (2024). The Ecampus has held

8000-574: The campaign began in 2017. Oregon State has varied and numerous partnership agreements with international institutions, including James Cook University in Australia , the University of Forestry in Bulgaria , Lincoln University in New Zealand and India's Gokula Education Foundation. Undergraduate admission to Oregon State is rated "selective" by U.S. News & World Report . OSU

8125-612: The cause of science, but do not have the kind of scientific achievements required of Fellows or Foreign Members. Honorary Fellows include the World Health Organization's Director-General Tedros Adhanom Ghebreyesus (2022), Bill Bryson (2013), Melvyn Bragg (2010), Robin Saxby (2015), David Sainsbury, Baron Sainsbury of Turville (2008), Onora O'Neill (2007), John Maddox (2000), Patrick Moore (2001) and Lisa Jardine (2015). Honorary Fellows are entitled to use

8250-606: The centerpiece of Corvallis, Oregon . The campus is 83 miles south of Portland, near the middle of the state's Willamette Valley . Much of the main campus was designed by landscape architect John Charles Olmsted in 1906. In 2008, Olmsted's early campus design was designated by the National Register of Historic Places as the Oregon State University Historic District. It is the only college or university campus in Oregon to hold

8375-471: The chemical bond" was the accounting of the structure of aromatic hydrocarbons , particularly the prototype, benzene . The best description of benzene had been made by the German chemist Friedrich Kekulé . He had treated it as a rapid interconversion between two structures, each with alternating single and double bonds , but with the double bonds of one structure in the locations where the single bonds were in

8500-406: The coast of Newport and serviced by the university's Hatfield Marine Science Center . The South PacWave Test Facility is an open ocean test site consisting of four berths, which occupy two square nautical miles of ocean with a cable route to shore of approximately 12 miles in length. The North PacWave Test Facility offers a site in state waters with streamlined permitting (the expected time to permit

8625-485: The concept of hybridization of atomic orbitals and analyzed the tetravalency of the carbon atom. At Caltech, Pauling struck up a close friendship with theoretical physicist Robert Oppenheimer at the University of California, Berkeley , who spent part of his research and teaching schedule as a visitor at Caltech each year. Pauling was also affiliated with Berkeley, serving as a visiting lecturer in physics and chemistry from 1929 to 1934. Oppenheimer even gave Pauling

8750-462: The crystalline minerals of his former work. The best X-ray pictures of proteins in the 1930s had been made by the British crystallographer William Astbury , but when Pauling tried, in 1937, to account for Astbury's observations quantum mechanically, he could not. It took eleven years for Pauling to explain the problem: his mathematical analysis was correct, but Astbury's pictures were taken in such

8875-775: The dangers associated with the development of nuclear weapons. His political activism prompted the US State Department to deny him a passport in 1952, when he was invited to speak at a scientific conference in London. In a speech before the US Senate on June 6 of the same year, Senator Wayne Morse publicly denounced the action of the State Department, and urged the Passport Division to reverse its decision. Pauling and his wife Ava were then issued

9000-567: The dawn of molecular genetics . His success with sickle cell anemia led Pauling to speculate that a number of other diseases, including mental illnesses such as schizophrenia , might result from flawed genetics. As chairman of the Division of Chemistry and Chemical Engineering and director of the Gates and Crellin Chemical Laboratories, he encouraged the hiring of researchers with a chemical-biomedical approach to mental illness,

9125-569: The day that the treaty went into force, October 10, 1963, the Nobel Prize Committee awarded Pauling the Nobel Peace Prize for 1962. (No prize had previously been awarded for that year.) They described him as "Linus Carl Pauling, who ever since 1946 has campaigned ceaselessly, not only against nuclear weapons tests, not only against the spread of these armaments, not only against their very use, but against all warfare as

9250-443: The development and administration of several other early Oregon colleges. Within a decade of its inception, college-level coursework was added to the academy's curriculum, making it the first public college in the region and a magnet for Oregon's young adults seeking a profession. The university adopted eight name variations during the 1800s and three more in the 1900s. As with many land-grant colleges, name changes were common around

9375-442: The discoveries that he had already found. Pauling also studied enzyme reactions and was among the first to point out that enzymes bring about reactions by stabilizing the transition state of the reaction, a view which is central to understanding their mechanism of action. He was also among the first scientists to postulate that the binding of antibodies to antigens would be due to a complementarity between their structures. Along

9500-524: The enrolled freshmen was 3.58, while the middle 50% range of SAT scores were 480-610 for critical reading, 490-630 for math, and 470-590 for writing. The middle 50% range of the ACT Composite score was 21–28. OSU has more majors, minors and special programs than any other university or college in Oregon. Research has played a central role in the university's overall operations for much of its history. Most of OSU's research continues at

9625-528: The fellowships described below: Every year, up to 52 new fellows are elected from the United Kingdom, the rest of the Commonwealth of Nations , and Ireland, which make up around 90% of the society. Each candidate is considered on their merits and can be proposed from any sector of the scientific community. Fellows are elected for life on the basis of excellence in science and are entitled to use

9750-415: The first publication. Part of Pauling's work on the nature of the chemical bond led to his introduction of the concept of orbital hybridization . While it is normal to think of the electrons in an atom as being described by orbitals of types such as s and p , it turns out that in describing the bonding in molecules, it is better to construct functions that partake of some of the properties of each. Thus

9875-542: The five rules now known as Pauling's rules . By 1929, he was promoted to associate professor, and by 1930, to full professor. In 1931, the American Chemical Society awarded Pauling the Langmuir Prize for the most significant work in pure science by a person 30 years of age or younger. The following year, Pauling published what he regarded as his most important paper, in which he first laid out

10000-540: The good of the Royal Society of London for Improving Natural Knowledge, and to pursue the ends for which the same was founded; that we will carry out, as far as we are able, those actions requested of us in the name of the Council; and that we will observe the Statutes and Standing Orders of the said Society. Provided that, whensoever any of us shall signify to the President under our hands, that we desire to withdraw from

10125-495: The high school senior had enough credits to enter Oregon State University (OSU), known then as Oregon Agricultural College. Lacking two American history courses required for his high school diploma , Pauling asked the school principal if he could take the courses concurrently during the spring semester. Denied, he left Washington High School in June without a diploma. The school awarded him an honorary diploma 45 years later, after he

10250-1531: The improvement of natural knowledge , including mathematics , engineering science , and medical science ". Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Benjamin Franklin (1756), Charles Babbage (1816), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Jagadish Chandra Bose (1920), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Prasanta Chandra Mahalanobis (1945), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955), Satyendra Nath Bose (1958), and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Raghunath Mashelkar (1998), Tim Berners-Lee (2001), Venki Ramakrishnan (2003), Atta-ur-Rahman (2006), Andre Geim (2007), Bai Chunli (2014), James Dyson (2015), Ajay Kumar Sood (2015), Subhash Khot (2017), Elon Musk (2018), Elaine Fuchs (2019) and around 8,000 others in total, including over 280 Nobel Laureates since 1900. As of October 2018 , there are approximately 1,689 living Fellows, Foreign and Honorary Members, of whom 85 are Nobel Laureates. Fellowship of

10375-480: The late 1920s, Pauling began publishing papers on the nature of the chemical bond . Between 1937 and 1938, he took a position as George Fischer Baker Non-Resident Lecturer in Chemistry at Cornell University . While at Cornell, he delivered a series of nineteen lectures and completed the bulk of his famous textbook The Nature of the Chemical Bond . It is based primarily on his work in this area that he received

10500-650: The legend that Pauling missed the structure of DNA because of the politics of the day (this was at the start of the McCarthy period in the United States). Politics did not play a critical role. Not only did Corey see the images at the time, but Pauling himself regained his passport within a few weeks and toured English laboratories well before writing his DNA paper. He had ample opportunity to visit Franklin's lab and see her work, but chose not to. Despite these times, Pauling chose to move on from them and be thankful for

10625-599: The medical usefulness of large doses of vitamins have gained much acceptance in the mainstream scientific community. He was married to the American human rights activist Ava Helen Pauling . Linus Carl Pauling was born on February 28, 1901, in Portland, Oregon , the firstborn child of Herman Henry William Pauling (1876–1910) and Lucy Isabelle "Belle" Darling (1881–1926). He was named "Linus Carl", in honor of Lucy's father, Linus, and Herman's father, Carl. His ancestry included German and English. In 1902, after his sister Pauline

10750-403: The molecular evolutionary clock, the idea that mutations in proteins and DNA accumulate at a constant rate over time . On September 16, 1952, Pauling opened a new research notebook with the words "I have decided to attack the problem of the structure of nuclei." On October 15, 1965, Pauling published his Close-Packed Spheron Model of the atomic nucleus in two well respected journals, Science and

10875-586: The nation in graduate nuclear engineering . In the early 2000s, researchers at the campus reactor developed the first working prototype Small Modular Reactor (SMR) to power large commercial operations, buildings, and large industrial facilities. More recently, Oregon State University has partnered with a leading manufacturer of SMRs, NuScale (a company started in part by OSU Faculty), to provide continued research and development for commercial applications. The university's College of Earth, Ocean and Atmospheric Sciences (CEOAS) operates several laboratories, including

11000-413: The nation to be designated a land, sun, sea and space grant university. OSU received a record high $ 449.9 million in research funding for the 2022 fiscal year and has ranked as the state's top earner in research funding for over 50 years. OSU is also one of the top five doctoral university destinations in the nation for Fulbright Scholars (2022–2023). The university's roots date to 1856, when it

11125-879: The newly renovated Meier & Frank building. The historic building features modern offices, classrooms and meeting spaces; which fill the entire second floor of what is now known as the Portland Building. Located next to downtown Portland's Pioneer Square, the OSU Portland Center accommodates offices for the OSU Extension Service, the OSU Foundation, the OSU Alumni Association, and the OSU Athletics Department. The downtown building provides

11250-427: The one 2s and three 2p orbitals in a carbon atom can be (mathematically) 'mixed' or combined to make four equivalent orbitals (called sp hybrid orbitals), which would be the appropriate orbitals to describe carbon compounds such as methane , or the 2s orbital may be combined with two of the 2p orbitals to make three equivalent orbitals (called sp hybrid orbitals), with the remaining 2p orbital unhybridized, which would be

11375-612: The other being Marie Curie . Pauling was one of the founders of the fields of quantum chemistry and molecular biology . His contributions to the theory of the chemical bond include the concept of orbital hybridisation and the first accurate scale of electronegativities of the elements. Pauling also worked on the structures of biological molecules, and showed the importance of the alpha helix and beta sheet in protein secondary structure . Pauling's approach combined methods and results from X-ray crystallography , molecular model building, and quantum chemistry. His discoveries inspired

11500-663: The other. Pauling showed that a proper description based on quantum mechanics was an intermediate structure which was a blend of each. The structure was a superposition of structures rather than a rapid interconversion between them. The name " resonance " was later applied to this phenomenon. In a sense, this phenomenon resembles those of hybridization and also polar bonding, both described above, because all three phenomena involve combining more than one electronic structure to achieve an intermediate result. In 1929, Pauling published five rules which help to predict and explain crystal structures of ionic compounds . These rules concern (1)

11625-521: The peptide bond. When it was learned at the Cavendish Laboratory that Pauling was working on molecular models of the structure of DNA, James Watson and Francis Crick were allowed to make a molecular model of DNA. They later benefited from unpublished data from Maurice Wilkins and Rosalind Franklin at King's College which showed evidence for a helix and planar base stacking along the helix axis. Early in 1953 Watson and Crick proposed

11750-535: The performance of outstanding services". In 1949, he served as president of the American Chemical Society . The aftermath of the Manhattan Project and his wife Ava's pacifism changed Pauling's life profoundly, and he became a peace activist. In June 1945, a "May-Johnson Bill" began that would become the Atomic Energy Act of 1946 (signed August 1, 1946). In November 1945, Pauling spoke to

11875-471: The physics literature, Physical Review Letters and other journals, I know that many physicists are interested in atomic nuclei, but none of them, so far as I have been able to discover, has been attacking the problem in the same way that I attack it. So I just move along at my own speed, making calculations ... Pauling had been practically apolitical until World War II . At the beginning of the Manhattan Project , Robert Oppenheimer invited him to be in charge of

12000-514: The post nominal letters HonFRS . Statute 12 is a legacy mechanism for electing members before official honorary membership existed in 1997. Fellows elected under statute 12 include David Attenborough (1983) and John Palmer, 4th Earl of Selborne (1991). The Council of the Royal Society can recommend members of the British royal family for election as Royal Fellow of the Royal Society . As of 2023 there are four royal fellows: Elizabeth II

12125-552: The proposal is being made. There is no limit on the number of nominations made each year. In 2015, there were 654 candidates for election as Fellows and 106 candidates for Foreign Membership. The Council of the Royal Society oversees the selection process and appoints 10 subject area committees, known as Sectional Committees, to recommend the strongest candidates for election to the Fellowship. The final list of up to 52 Fellowship candidates and up to 10 Foreign Membership candidates

12250-950: The ratio of cation radius to anion radius, (2) the electrostatic bond strength, (3) the sharing of polyhedron corners, edges and faces, (4) crystals containing different cations, and (5) the rule of parsimony. In the mid-1930s, Pauling, strongly influenced by the biologically oriented funding priorities of the Rockefeller Foundation's Warren Weaver , decided to strike out into new areas of interest. Although Pauling's early interest had focused almost exclusively on inorganic molecular structures, he had occasionally thought about molecules of biological importance, in part because of Caltech's growing strength in biology. Pauling interacted with such great biologists as Thomas Hunt Morgan , Theodosius Dobzhanski , Calvin Bridges and Alfred Sturtevant . His early work in this area included studies of

12375-423: The same lines, with the physicist turned biologist Max Delbrück , he wrote an early paper arguing that DNA replication was likely to be due to complementarity , rather than similarity, as suggested by a few researchers. This was made clear in the model of the structure of DNA that Watson and Crick discovered. In November 1949, Pauling, Harvey Itano , S. J. Singer and Ibert Wells published " Sickle Cell Anemia,

12500-499: The school's first president, William A. Finley . On August 22, 1868, the official articles of incorporation were filed for Oregon State University, known then as Corvallis College. Two months later, on October 27, 1868, OSU was chartered as the state's first public college. To help ensure the early college would be well funded, the Oregon Legislative Assembly designated it Oregon's Land-grant university and

12625-566: The school's name changed so did its mission. Coursework in the sciences and technology became the most popular majors starting in 1900. In 1914, the Oregon State Board of Higher Education , known then as the State Board of Higher Curricula, began assigning specific colleges to Oregon State University and the University of Oregon in an effort to eliminate duplication. "...the board confined studies in engineering and commerce to

12750-476: The selfish, the overly ambitious, the misguided, the unscrupulous, who seek to oppress the great body of mankind in order that they themselves may profit – and we must always be on the alert against this threat, and must fight it with vigor when it becomes dangerous." In 1946, he joined the Emergency Committee of Atomic Scientists , chaired by Albert Einstein . Its mission was to warn the public of

12875-497: The seventh-largest engineering college in the nation for 2023. Undergraduate enrollment for all colleges combined averages over 32,000 while an additional 5,000 students are engaged in post-graduate coursework through the university. In 2023, over 37,000 students were enrolled at OSU – making it the largest university in the state. Out-of-state students typically make up over one-quarter of the student body. Since its founding, over 272,000 students have graduated from OSU. The university

13000-437: The shell structure of nuclei from pure geometrical considerations related to Platonic solids rather than starting from an independent particle model as in the usual shell model . In an interview given in 1990 Pauling commented on his model: Now recently, I have been trying to determine detailed structures of atomic nuclei by analyzing the ground state and excited state vibrational bends, as observed experimentally. From reading

13125-606: The space for lectures and international conferences. The OSU Portland Center is also an important part of the OSU Advantage partnership. The partnership brings members of private industry, from throughout the world, to Portland to discuss proposed commercialization initiatives. Recognized as one of the top marine laboratories in the nation, OSU's Hatfield Marine Science Center has been a fixture in Newport, Oregon for over 50 years. The campus serves as an oceanographic research base for six state and federal agencies and also

13250-518: The start of the 20th century and helped schools align with the period's largest available federal grants in agricultural research. Corvallis area Freemasons played a leading role in developing the early school. Several of the university's largest buildings are named after these early founders. The school offered its first college-level curriculum in 1865, under the administration of the Methodist Episcopal Church, South and

13375-552: The state. Programs include 4-H Youth Development, Agriculture and Natural Resources (includes OSU Master Gardener ), Family and Community Health/SNAP-Ed , Forestry and Natural Resources , OSU Open Campus, K-12 Outdoor School , and Oregon Sea Grant . Together with university leaders, the Oregon State University Foundation publicly launched Oregon State's first comprehensive fundraising campaign, The Campaign for OSU, on October 26, 2007, with

13500-419: The structure of hemoglobin with his student Charles D. Coryell . He demonstrated that the hemoglobin molecule changes structure when it gains or loses an oxygen molecule. As a result of this observation, he decided to conduct a more thorough study of protein structure in general. He returned to his earlier use of X-ray diffraction analysis. But protein structures were far less amenable to this technique than

13625-497: The university with a more central location, in the state's largest city, to maintain a base of operations. Aside from offices, the second floor also provides classroom space for teaching, research and meeting space for outreach engagement - similar to the work at OSU's other campuses in Corvallis and Bend. Executives and university scientists working on major initiatives, such as the Marine Studies Initiative, use

13750-480: The work of Rosalind Franklin , James Watson , Francis Crick , and Maurice Wilkins on the structure of DNA , which in turn made it possible for geneticists to crack the DNA code of all organisms. In his later years, he promoted nuclear disarmament , as well as orthomolecular medicine , megavitamin therapy , and dietary supplements , especially ascorbic acid (commonly known as Vitamin C). None of his ideas concerning

13875-410: The world, its agricultural sciences program in the top 50 worldwide, and its earth sciences, ecology and water resources program among the top 100 worldwide. Agriculture and forestry at Oregon State University rank 26th in the world (11th in the U.S.), according to QS World University Rankings in 2021. In 2012, ECONorthwest conducted an economic impact analysis that found that each year OSU has

14000-474: The world." In high school, Pauling conducted chemistry experiments by scavenging equipment and material from an abandoned steel plant. With an older friend, Lloyd Simon, Pauling set up Palmon Laboratories in Simon's basement. They approached local dairies offering to perform butterfat samplings at cheap prices but dairymen were wary of trusting two boys with the task, and the business ended in failure. At age 15,

14125-402: Was a triple helix ; his model contained several basic mistakes, including a proposal of neutral phosphate groups, an idea that conflicted with the acidity of DNA. Sir Lawrence Bragg had been disappointed that Pauling had won the race to find the alpha helix structure of proteins. Bragg's team had made a fundamental error in making their models of protein by not recognizing the planar nature of

14250-533: Was approved in 2023. The complex will include 70+ studio-style apartments and a small number of two-bedroom apartments near the Newport campus. All academic courses at OSU operate under the quarter-system, which breaks down into four, 11-week terms. The professional disciplines taught at OSU are divided among 11 colleges, an honors college, and a graduate school. Each college has a dean who is responsible for all faculty, staff, students and academic programs. Colleges are divided into schools or departments, administered by

14375-640: Was awarded a Guggenheim Fellowship to travel to Europe, to study under German physicist Arnold Sommerfeld in Munich, Danish physicist Niels Bohr in Copenhagen and Austrian physicist Erwin Schrödinger in Zürich . All three were experts in the new field of quantum mechanics and other branches of physics. Pauling became interested in how quantum mechanics might be applied in his chosen field of interest,

14500-436: Was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have won more than one Nobel Prize (the others being Marie Curie , John Bardeen , Frederick Sanger , and Karl Barry Sharpless ). Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields,

14625-441: Was awarded two Nobel Prizes. Pauling held a number of jobs to earn money for his future college expenses, including working part-time at a grocery store for US$ 8 per week (equivalent to US$ 220 in 2023). His mother arranged an interview with the owner of a number of manufacturing plants in Portland, Mr. Schwietzerhoff, who hired him as an apprentice machinist at a salary of US$ 40 per month (equivalent to US$ 1,120 in 2023). This

14750-643: Was born, Pauling's parents decided to move out of Portland to find more affordable and spacious living quarters than their one-room apartment. Lucy stayed with her husband's parents in Oswego until Herman brought the family to Salem , where he worked briefly as a traveling salesman for the Skidmore Drug Company. Within a year of Lucile's birth in 1904, Herman Pauling moved his family to Oswego, Oregon where he opened his own drugstore. He moved his family to Condon, Oregon , in 1905. By 1906, Herman Pauling

14875-502: Was childhood pal and lifelong best friend Lloyd Jeffress. He was active in campus life and founded the school's chapter of the Delta Upsilon fraternity. After his second year, he planned to take a job in Portland to help support his mother. The college offered him a position teaching quantitative analysis , a course he had just finished taking himself. He worked forty hours a week in the laboratory and classroom and earned US$ 100

15000-456: Was creating the world's best images. They were key to Watson's and Crick's success. Pauling did not see them before devising his mistaken DNA structure, although his assistant Robert Corey did see at least some of them, while taking Pauling's place at a summer 1952 protein conference in England. Pauling had been prevented from attending because his passport was withheld by the State Department on suspicion that he had Communist sympathies. This led to

15125-530: Was first offered in the early 1930s, with the conferral of four Doctor of Philosophy degrees in 1935. That year also saw the creation of the first summer session. The growing diversity in degrees offered by the college led leaders to adopt the name "Oregon State College" in 1937. The name Oregon State University was adopted on March 6, 1961, by a legislative act signed into law by Governor Mark Hatfield . . The 420-acre (170 ha), tree-lined main campus serves as an internationally recognized arboretum and

15250-411: Was founded as a primary and preparatory community school known as Corvallis Academy. The school's first administrator and teacher was John Wesley Johnson , a famous figure in Oregon higher education. Johnson received his secondary education in Corvallis and his undergraduate from Pacific University before working at the new academy. He later attended Yale University and became an instrumental figure in

15375-421: Was not a Royal Fellow, but provided her patronage to the society, as all reigning British monarchs have done since Charles II of England . Prince Philip, Duke of Edinburgh (1951) was elected under statute 12, not as a Royal Fellow. The election of new fellows is announced annually in May, after their nomination and a period of peer-reviewed selection. Each candidate for Fellowship or Foreign Membership

15500-534: Was soon raised to US$ 50 per month. Pauling also set up a photography laboratory with two friends. In September 1917, Pauling was finally admitted by Oregon State University. He immediately resigned from the machinist's job and informed his mother, who saw no point in a university education, of his plans. In his first semester, Pauling registered for two courses in chemistry, two in mathematics, mechanical drawing, introduction to mining and use of explosives, modern English prose, gymnastics and military drill. His roommate

15625-523: Was suffering from recurrent abdominal pain . He died of a perforated ulcer on June 11, 1910, leaving Lucy to care for Linus, Lucile and Pauline. Pauling attributes his interest in becoming a chemist to being amazed by experiments conducted by a friend, Lloyd A. Jeffress , who had a small chemistry lab kit. He later wrote: "I was simply entranced by chemical phenomena, by the reactions in which substances, often with strikingly different properties, appear; and I hoped to learn more and more about this aspect of

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