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167-534: In some languages and regions, "apothecary" is not archaic and has become those languages' term for "pharmacy" or a pharmacist who owns one. Apothecaries' investigation of herbal and chemical ingredients was a precursor to the modern sciences of chemistry and pharmacology . In addition to dispensing herbs and medicine, apothecaries offered general medical advice and a range of services that are now performed by other specialist practitioners, such as surgeons and obstetricians . Apothecary shops sold ingredients and

334-549: A 'dietary supplement', though the FDA may withdraw a product from sale should it prove harmful. Canadian regulations are described by the Natural and Non-prescription Health Products Directorate which requires an eight-digit Natural Product Number or Homeopathic Medicine Number on the label of licensed herbal medicines or dietary supplements. Some herbs, such as cannabis and coca , are outright banned in most countries though coca

501-507: A 2018 study, the FDA identified active pharmaceutical additives in over 700 analyzed dietary supplements sold as "herbal", "natural" or "traditional". The undisclosed additives included "unapproved antidepressants and designer steroids", as well as prescription drugs , such as sildenafil or sibutramine . Researchers at the University of Adelaide found in 2014 that almost 20 percent of herbal remedies surveyed were not registered with

668-503: A basis as herbal remedies, including artemisinin , digitalis , quinine and taxanes . In 2015, the Australian Government's Department of Health published the results of a review of alternative therapies that sought to determine if any were suitable for being covered by health insurance ; herbalism was one of 17 topics evaluated for which no clear evidence of effectiveness was found. Establishing guidelines to assess

835-584: A collection of more than 800 prescriptions. It lists over 700 different drugs. In ancient India, the Sushruta Samhita , a compendium on the practice of medicine and medical formulations, has been traced back to the 1st century BC. The Shen-nung pen ts'ao ching , a Chinese book on agriculture and medicinal plants (3rd century AD), is considered a foundational material for Chinese medicine and herbalism and became an important source for Chinese apothecaries. The book, which documented 365 treatments, had

1002-465: A customer should inform a herbalist of their consumption of actual prescription and other medication. For example, dangerously low blood pressure may result from the combination of a herbal remedy that lowers blood pressure together with prescription medicine that has the same effect. Some herbs may amplify the effects of anticoagulants. Certain herbs as well as common fruit interfere with cytochrome P450, an enzyme critical to much drug metabolism. In

1169-421: A few families and still others lived on isolated farms spread over the countryside. There were also areas where the pattern was a mix of two or more of those systems. Unlike in the late Roman period, there was no sharp break between the legal status of the free peasant and the aristocrat, and it was possible for a free peasant's family to rise into the aristocracy over several generations through military service to

1336-464: A focus on roots and grass. It had treatments which came from minerals, roots and grass, and animals. Many of the mentioned drugs and their uses are still followed today. Ginseng's use as a sexual stimulant and aid for erectile dysfunction stems from this book. Ma huang, an herb first mentioned in the book, led to the introduction of the drug ephedrine into modern medicine. According to Sharif Kaf al-Ghazal, and S. Hadzovic, apothecary shops existed during

1503-631: A herb that was known in Chinese medicine to treat fever. There is limited scientific evidence for the safety and efficacy of many plants used in 21st-century herbalism, which generally does not provide standards for purity or dosage. The scope of herbal medicine sometimes includes fungal and bee products, as well as minerals , shells and certain animal parts. Paraherbalism describes alternative and pseudoscientific practices of using unrefined plant or animal extracts as unproven medicines or health-promoting agents. Paraherbalism relies on

1670-601: A king to rule over them all. By the late sixth century, this arrangement had been replaced by a permanent monarchy, the Kingdom of the Lombards . The invasions brought new ethnic groups to Europe, although some regions received a larger influx of new peoples than others. In Gaul for instance, the invaders settled much more extensively in the north-east than in the south-west. Slavs settled in Central and Eastern Europe and

1837-500: A long and colorful history in Europe, associated with "sorcery", "magic" and intrigue. Although not frequent, adverse reactions have been reported for herbs in widespread use. On occasion serious untoward outcomes have been linked to herb consumption. A case of major potassium depletion has been attributed to chronic licorice ingestion, and consequently professional herbalists avoid the use of licorice where they recognize that this may be

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2004-410: A lower ethanol percentage than tinctures. They are usually made by vacuum distilling tinctures. Dry extracts are extracts of plant material that are evaporated into a dry mass. They can then be further refined to a capsule or tablet. The exact composition of a herbal product is influenced by the method of extraction. A tea will be rich in polar components because water is a polar solvent . Oil on

2171-506: A mixture of pure ethanol with water) with the herb. A completed tincture has an ethanol percentage of at least 25% (sometimes up to 90%). Non-alcoholic tinctures can be made with glycerin but it is believed to be less absorbed by the body than alcohol based tinctures and has a shorter shelf life. Herbal wine and elixirs are alcoholic extracts of herbs, usually with an ethanol percentage of 12–38%. Extracts include liquid extracts, dry extracts, and nebulisates. Liquid extracts are liquids with

2338-527: A physical means of purging intestinal parasites. Sick animals tend to forage plants rich in secondary metabolites , such as tannins and alkaloids . Middle Ages In the history of Europe , the Middle Ages or medieval period lasted approximately from the 5th to the late 15th centuries, similarly to the Post-classical period of global history . It began with the fall of

2505-567: A powerful lord. Roman city life and culture changed greatly in the early Middle Ages. Although Italian cities remained inhabited, they contracted significantly in size. Rome, for instance, shrank from a population of hundreds of thousands to around 30,000 by the end of the 6th century. Roman temples were converted into Christian churches and city walls remained in use. In Northern Europe, cities also shrank, while civic monuments and other public buildings were raided for building materials. The establishment of new kingdoms often meant some growth for

2672-466: A practical skill rather than a sign of elite status. In the 4th century, Jerome (d. 420) dreamed that God rebuked him for spending more time reading Cicero than the Bible . By the 6th century, Gregory of Tours (d. 594) had a similar dream, but instead of being chastised for reading Cicero, he was chastised for learning shorthand . By the late 6th century, the principal means of religious instruction in

2839-425: A risk. Black cohosh has been implicated in a case of liver failure. Few studies are available on the safety of herbs for pregnant women, and one study found that use of complementary and alternative medicines is associated with a 30% lower ongoing pregnancy and live birth rate during fertility treatment. Examples of herbal treatments with likely cause-effect relationships with adverse events include aconite (which

3006-474: A small foothold in southern Spain. Justinian's reconquests have been criticised by historians for overextending his realm and setting the stage for the early Muslim conquests , but many of the difficulties faced by Justinian's successors were due not just to over-taxation to pay for his wars but to the essentially civilian nature of the empire, which made raising troops difficult. In the Eastern Empire

3173-640: A specific profession of herb mixer and combiner (herbalist), called Acaraki . The book from Mataram dated from circa 1700 contains 3,000 entries of jamu herbal recipes, while Javanese classical literature Serat Centhini (1814) describes some jamu herbal concoction recipes. Though possibly influenced by Indian Ayurveda systems, the Indonesia archipelago holds numerous indigenous plants not found in India, including plants similar to those in Australia beyond

3340-551: A topical. Salves , oils, balms , creams, and lotions are other forms of topical delivery mechanisms. Most topical applications are oil extractions of herbs. Taking a food grade oil and soaking herbs in it for anywhere from weeks to months allows certain phytochemicals to be extracted into the oil. This oil can then be made into salves, creams, lotions, or simply used as an oil for topical application. Many massage oils, antibacterial salves, and wound healing compounds are made this way. Inhalation , as in aromatherapy , can be used as

3507-558: A traditional Chinese treatment for intermittent fevers. In India, Ayurvedic medicine has quite complex formulas with 30 or more ingredients, including a sizable number of ingredients that have undergone " alchemical processing ", chosen to balance dosha . In Ladakh, Lahul-Spiti, and Tibet, the Tibetan Medical System is prevalent, also called the "Amichi Medical System". Over 337 species of medicinal plants have been documented by C.P. Kala . Those are used by Amchis,

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3674-402: A treatment. It is a popular misconception that herbal medicines are safe and side-effect free. Consumption of herbs may cause adverse effects . Furthermore, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." Proper double-blind clinical trials are needed to determine

3841-536: Is apoteker , which was borrowed from the Dutch apotheker . In Yiddish the word is אַפּטייק apteyk . Use of the term in the names of businesses varies with time and location. It is generally an Americanism, though some areas of the United States use it to invoke an experience of nostalgic revival and it has been used for a wide variety of businesses; while in other areas such as California its use

4008-438: Is a conspiracy to suppress safe and effective herbs, herbs cannot cause harm, whole herbs are more effective than molecules isolated from the plants, herbs are superior to drugs, the doctrine of signatures (the belief that the shape of the plant indicates its function) is valid, dilution of substances increases their potency (a doctrine of the pseudoscience of homeopathy ), astrological alignments are significant, animal testing

4175-546: Is banned in the European Union), St. John's wort , khat , betel nut , the restricted herb ephedra , and guarana . There is also concern with respect to the numerous well-established interactions of herbs and drugs. In consultation with a physician, usage of herbal remedies should be clarified, as some herbal remedies have the potential to cause adverse drug interactions when used in combination with various prescription and over-the-counter pharmaceuticals, just as

4342-647: Is legal in most of the South American countries where it is grown. The Cannabis plant is used as a herbal medicine , and as such is legal in some parts of the world. Since 2004, the sales of ephedra as a dietary supplement is prohibited in the United States by the FDA, and subject to Schedule III restrictions in the United Kingdom. Herbalism has been criticized as a potential " minefield " of unreliable product quality, safety hazards, and

4509-476: Is legally obligated to be run at all times by at least one Apotheker (male) or Apothekerin (female), who actually has an academic degree as a pharmacist – in German Pharmazeut (male) or Pharmazeutin (female) – and has obtained the professional title Apotheker by either working in the field for numerous years, usually by working in a pharmacy store, or taking additional exams. Thus a Pharmazeut

4676-672: Is no universally agreed upon end date. Depending on the context, events such as the conquest of Constantinople by the Turks in 1453, Christopher Columbus 's first voyage to the Americas in 1492, or the Protestant Reformation in 1517 are sometimes used. English historians often use the Battle of Bosworth Field in 1485 to mark the end of the period. For Spain, dates commonly used are the death of King Ferdinand II in 1516,

4843-489: Is noon apothecarie, I shal myself to herbes techen yow, That shul been for youre hele and for youre prow. In modern English, this can be translated as: ... and you should not linger, Though in this town there is no apothecary, I shall teach you about herbs myself, That will be for your health and for your pride. In Renaissance Italy , Italian Nuns became a prominent source for medicinal needs. At first they used their knowledge in non-curative uses in

5010-558: Is not always an Apotheker . Magdalena Neff became the first woman to gain a medical qualification in Germany when she studied pharmacy at the Technical University of Karlsruhe and later passed the apothecary's examination in 1906. Apothecaries used their own measurement system, the apothecaries' system , to provide precise weighing of small quantities. Apothecaries dispensed vials of poisons as well as medicines, and as

5177-522: Is not appropriate to indicate human effects, anecdotal evidence is an effective means of proving a substance works and herbs were created by God to cure disease. Tyler suggests that none of these beliefs have any basis in fact. Up to 80% of the population in Africa uses traditional medicine as primary health care. Native Americans used about 2,500 of the approximately 20,000 plant species that are native to North America. In Andean healing practices,

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5344-437: Is not mandated in the United States, but even products made to the same specification may differ as a result of biochemical variations within a species of plant. Plants have chemical defense mechanisms against predators that can have adverse or lethal effects on humans. Examples of highly toxic herbs include poison hemlock and nightshade. They are not marketed to the public as herbs, because the risks are well known, partly due to

5511-462: Is often a legally restricted herb), Ayurvedic remedies , broom , chaparral , Chinese herb mixtures, comfrey , herbs containing certain flavonoids, germander , guar gum , liquorice root , and pennyroyal . Examples of herbs that may have long-term adverse effects include ginseng , the endangered herb goldenseal , milk thistle , senna , aloe vera juice , buckthorn bark and berry , cascara sagrada bark , saw palmetto , valerian , kava (which

5678-399: Is restricted to licensed pharmacies. The profession of apothecary can be dated back at least to 2600 BC to ancient Babylon , which provides one of the earliest records of the practice of the apothecary. Clay tablets have been found with medical texts recording symptoms, prescriptions, and the directions for compounding. The Papyrus Ebers from ancient Egypt, written around 1500 BC, contain

5845-420: Is safer and potentially more effective, for which there is no evidence either condition applies. Phytochemical researcher Varro Eugene Tyler described paraherbalism as "faulty or inferior herbalism based on pseudoscience", using scientific terminology but lacking scientific evidence for safety and efficacy. Tyler listed ten fallacies that distinguished herbalism from paraherbalism, including claims that there

6012-403: Is still the case, medicines could be either beneficial or harmful if inappropriately used. Protective methods to prevent accidental ingestion of poisons included the use of specially-shaped containers for potentially poisonous substances such as laudanum . Apothecary businesses were typically family-run, and wives or other women of the family worked alongside their husbands in the shops, learning

6179-429: Is the pseudoscientific use of extracts of plant or animal origin as supposed medicines or health-promoting agents. Phytotherapy differs from plant-derived medicines in standard pharmacology because it does not isolate and standardize the compounds from a given plant believed to be biologically active. It relies on the false belief that preserving the complexity of substances from a given plant with less processing

6346-539: The fyrd , which were led by the local elites. In military technology, one of the main changes was the return of the crossbow , which had been known in Roman times and reappeared as a military weapon during the last part of the Early Middle Ages. Another change was the introduction of the stirrup, which increased the effectiveness of cavalry as shock troops. A technological advance that had implications beyond

6513-717: The Alans , Vandals , and Suevi crossed into Gaul ; over the next three years they spread across Gaul and in 409 crossed the Pyrenees Mountains into modern-day Spain. The Migration Period began, when various peoples, initially largely Germanic peoples , moved across Europe. The Franks , Alemanni , and the Burgundians all ended up in northern Gaul while the Angles , Saxons , and Jutes settled in Britain , and

6680-529: The Benedictine Rule for Western monasticism during the 6th century, detailing the administrative and spiritual responsibilities of a community of monks led by an abbot . Monks and monasteries had a deep effect on the religious and political life of the Early Middle Ages, in various cases acting as land trusts for powerful families, centres of propaganda and royal support in newly conquered regions, and bases for missions and proselytisation. They were

6847-697: The Carolingian dynasty , briefly established the Carolingian Empire during the later 8th and early 9th centuries. It covered much of Western Europe but later succumbed to the pressures of internal civil wars combined with external invasions: Vikings from the north, Magyars from the east, and Saracens from the south. During the High Middle Ages, which began after 1000, the population of Europe increased greatly as technological and agricultural innovations allowed trade to flourish and

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7014-548: The Committee on Herbal Medicinal Products . In the United States, herbal remedies are regulated dietary supplements by the Food and Drug Administration (FDA) under current good manufacturing practice (cGMP) policy for dietary supplements. Manufacturers of products falling into this category are not required to prove the safety or efficacy of their product so long as they do not make 'medical' claims or imply uses other than as

7181-531: The Desert Fathers of Egypt and Syria . Most European monasteries were of the type that focuses on community experience of the spiritual life, called cenobitism , which was pioneered by Pachomius (d. 348) in the 4th century. Monastic ideals spread from Egypt to Western Europe in the 5th and 6th centuries through hagiographical literature such as the Life of Anthony . Benedict of Nursia (d. 547) wrote

7348-610: The Ebers papyrus dates from about 1550 BCE, and covers more than 700 compounds, mainly of plant origin. The earliest known Greek herbals came from Theophrastus of Eresos who, in the 4th century BCE, wrote in Greek Historia Plantarum , from Diocles of Carystus who wrote during the 3rd century BCE, and from Krateuas who wrote in the 1st century BCE. Only a few fragments of these works have survived intact, but from what remains, scholars have noted overlap with

7515-584: The Gregorian chant in liturgical music for the churches. An important activity for scholars during this period was the copying, correcting, and dissemination of basic works on religious and secular topics, with the aim of encouraging learning. New works on religious topics and schoolbooks were also produced. Grammarians of the period modified the Latin language, changing it from the Classical Latin of

7682-714: The Macedonian dynasty . Commerce revived and the emperors oversaw the extension of a uniform administration to all the provinces. The military was reorganised, which allowed the emperors John I (r. 969–976) and Basil II (r. 976–1025) to expand the frontiers of the empire on all fronts. The imperial court was the centre of a revival of classical learning, a process known as the Macedonian Renaissance . Writers such as John Geometres ( fl. early 10th century) composed new hymns, poems, and other works. Missionary efforts by both Eastern and Western clergy resulted in

7849-486: The Medieval Warm Period climate change allowed crop yields to increase. Manorialism , the organisation of peasants into villages that owed rent and labour services to the nobles , and feudalism , the political structure whereby knights and lower-status nobles owed military service to their overlords in return for the right to rent from lands and manors , were two of the ways society was organized in

8016-730: The Middle Ages in Baghdad , operated by pharmacists in 754 during the Abbasid Caliphate , or Islamic Golden Age . Apothecaries were also active in Al-Andalus by the 11th century. By the end of the 14th century, Geoffrey Chaucer ( c.  1342 –1400) was mentioning an English apothecary in the Canterbury Tales , specifically " The Nun's Priest's Tale " as Pertelote speaks to Chauntecleer (lines 181–184): ... and for ye shal nat tarie, Though in this toun

8183-774: The Therapeutic Goods Administration , despite this being a condition for their sale. They also found that nearly 60 percent of products surveyed had ingredients that did not match what was on the label. Out of 121 products, only 15 had ingredients that matched their TGA listing and packaging. In 2015, the New York Attorney General issued cease and desist letters to four major U.S. retailers ( GNC , Target , Walgreens , and Walmart ) who were accused of selling herbal supplements that were mislabeled and potentially dangerous. Twenty-four products were tested by DNA barcoding as part of

8350-1036: The Wallace Line . Jamu practices may vary from region to region, and are often not recorded, especially in remote areas of the country. Although primarily herbal, some Jamu materials are acquired from animals, such as honey , royal jelly , milk, and Ayam Kampung eggs . Herbalists tend to use extracts from parts of plants, such as the roots or leaves, believing that plants are subject to environmental pressures and therefore develop resistance to threats such as radiation, reactive oxygen species and microbial attack to survive, providing defensive phytochemicals of use in herbalism. Indigenous healers often claim to have learned by observing that sick animals change their food preferences to nibble at bitter herbs they would normally reject. Field biologists have provided corroborating evidence based on observation of diverse species, such as chickens, sheep, butterflies , and chimpanzees . The habit of changing diet has been shown to be

8517-468: The 17th-century German historian Christoph Cellarius divided history into three periods: ancient, medieval, and modern. The most commonly given starting point for the Middle Ages is around 500, with the date of 476 first used by Bruni. Later starting dates are sometimes used in the outer parts of Europe. For Europe as a whole, 1500 is often considered to be the end of the Middle Ages, but there

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8684-478: The 5th and the 7th centuries, going first to England and Scotland and then on to the continent. Under such monks as Columba (d. 597) and Columbanus (d. 615), they founded monasteries, taught in Latin and Greek, and authored secular and religious works. The Early Middle Ages witnessed the rise of monasticism in the West. The shape of European monasticism was determined by traditions and ideas that originated with

8851-731: The 5th century. The Eastern Empire was marked by closer relations between the political state and Christian Church, with doctrinal matters assuming an importance in Eastern politics that they did not have in Western Europe. Legal developments included the codification of Roman law ; the first effort—the Codex Theodosianus —was completed in 438. Under Emperor Justinian (r. 527–565), another compilation took place—the Corpus Juris Civilis . Justinian also oversaw

9018-685: The 6th and 7th centuries, all of them ruled by the Merovingian dynasty, who were descended from Clovis. The 7th century was a tumultuous period of wars between Austrasia and Neustria. Such warfare was exploited by Pippin (d. 640), the Mayor of the Palace for Austrasia who became the power behind the Austrasian throne. Later members of his family inherited the office, acting as advisers and regents. One of his descendants, Charles Martel (d. 741), won

9185-611: The Act [21 U.S.C. § 321(g)(1)], because they are intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease and/or intended to affect the structure or any function of the body" when no such evidence existed. During the COVID-19 pandemic , the FDA and U.S. Federal Trade Commission issued warnings to several hundred American companies for promoting false claims that herbal products could prevent or treat COVID-19 disease . The World Health Organization (WHO),

9352-649: The American Herbalist Guild, "there is currently no licensing or certification for herbalists in any state that precludes the rights of anyone to use, dispense, or recommend herbs." However, there are U.S. federal restrictions for marketing herbs as cures for medical conditions, or essentially practicing as an unlicensed physician. Over the years 2017–2021, the U.S. Food and Drug Administration (FDA) issued warning letters to numerous herbalism companies for illegally marketing products under "conditions that cause them to be drugs under section 201(g)(1) of

9519-651: The Arabs. The migrations and invasions of the 4th and 5th centuries disrupted trade networks around the Mediterranean. African goods stopped being imported into Europe, first disappearing from the interior and by the 7th century found only in a few cities such as Rome or Naples . By the end of the 7th century, under the impact of the Muslim conquests , African products were no longer found in Western Europe. The replacement of goods from long-range trade with local products

9686-536: The Bald received the western Frankish lands, comprising most of modern-day France. Charlemagne's grandsons and great-grandsons divided their kingdoms between their descendants, eventually causing all internal cohesion to be lost. In 987 the Carolingian dynasty was replaced in the western lands, with the crowning of Hugh Capet (r. 987–996) as king. In the eastern lands the dynasty had died out earlier, in 911, with

9853-623: The Balkan Peninsula. The settlement of peoples was accompanied by changes in languages. Latin , the literary language of the Western Roman Empire, was gradually replaced by vernacular languages which evolved from Latin, but were distinct from it, collectively known as Romance languages . These changes from Latin to the new languages took many centuries. Greek remained the language of the Byzantine Empire, but

10020-643: The Battle of Poitiers in 732, halting the advance of Muslim armies across the Pyrenees. Great Britain was divided into small states dominated by the kingdoms of Northumbria , Mercia , Wessex , and East Anglia which descended from the Anglo-Saxon invaders. Smaller kingdoms in present-day Wales and Scotland were still under the control of the native Britons and Picts . Ireland was divided into even smaller political units, usually known as tribal kingdoms, under

10187-577: The Byzantine Empire, as the assumption of the imperial title by the Carolingians asserted their equivalence to the Byzantine state. There were several differences between the newly established Carolingian Empire and both the older Western Roman Empire and the concurrent Byzantine Empire. The Frankish lands were rural in character, with only a few small cities. Most of the people were peasants settled on small farms. Little trade existed and much of that

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10354-523: The Byzantine Empire, which he sealed with the marriage of his son Otto II (r. 967–983) to Theophanu (d. 991), daughter of an earlier Byzantine Emperor Romanos II (r. 959–963). By the late 10th century Italy had been drawn into the Ottonian sphere after a period of instability; Otto III (r. 996–1002) spent much of his later reign in the kingdom. The western Frankish kingdom was more fragmented, and although kings remained nominally in charge, much of

10521-648: The Christian period as nova (or "new"). Petrarch regarded the post-Roman centuries as " dark " compared to the "light" of classical antiquity . Leonardo Bruni was the first historian to use tripartite periodisation in his History of the Florentine People (1442), with a middle period "between the fall of the Roman Empire and the revival of city life sometime in late eleventh and twelfth centuries". Tripartite periodisation became standard after

10688-660: The Church had widened to the extent that the cultural and religious differences were greater than the similarities. The formal break, known as the East–West Schism , came in 1054, when the papacy and the patriarchy of Constantinople clashed over papal supremacy and excommunicated each other, which led to the division of Christianity into two Churches—the Western branch became the Roman Catholic Church and

10855-499: The Church had become music and art rather than the book. Most intellectual efforts went towards imitating classical scholarship, but some original works were created, along with now-lost oral compositions. The writings of Sidonius Apollinaris (d. 489), Cassiodorus (d. c.  585 ), and Boethius (d. c. 525) were typical of the age. Changes also took place among laymen, as aristocratic culture focused on great feasts held in halls rather than on literary pursuits. Clothing for

11022-704: The Dnieper River in modern Ukraine to the Adriatic Sea. By 1018, the last Bulgarian nobles had surrendered to the Byzantine Empire. Few large stone buildings were constructed between the Constantinian basilicas of the 4th century and the 8th century, although many smaller ones were built during the 6th and 7th centuries. By the beginning of the 8th century, the Carolingian Empire revived the basilica form of architecture. One feature of

11189-534: The Early Middle Ages are mostly illuminated manuscripts and carved ivories , originally made for metalwork that has since been melted down. Objects in precious metals were the most prestigious form of art, but almost all are lost except for a few crosses such as the Cross of Lothair , several reliquaries , and finds such as the Anglo-Saxon burial at Sutton Hoo and the hoards of Gourdon from Merovingian France, Guarrazar from Visigothic Spain and Nagyszentmiklós near Byzantine territory. There are survivals from

11356-457: The Early Middle Ages. The large-scale movements of the Migration Period , including various Germanic peoples , formed new kingdoms in what remained of the Western Roman Empire. In the 7th century, North Africa and the Middle East—once part of the Byzantine Empire —came under the rule of the Umayyad Caliphate , an Islamic empire, after conquest by Muhammad's successors . Although there were substantial changes in society and political structures,

11523-455: The Eastern branch the Eastern Orthodox Church . The ecclesiastical structure of the Roman Empire survived the movements and invasions in the west mostly intact, but the papacy was little regarded, and few of the Western bishops looked to the bishop of Rome for religious or political leadership. Many of the popes prior to 750 were more concerned with Byzantine affairs and Eastern theological controversies. The register, or archived copies of

11690-427: The Eastern emperors to pay tribute. They remained a strong power until 796. An additional problem to face the empire came as a result of the involvement of Emperor Maurice (r. 582–602) in Persian politics when he intervened in a succession dispute . This led to a period of peace, but when Maurice was overthrown, the Persians invaded and during the reign of Emperor Heraclius (r. 610–641) controlled large chunks of

11857-432: The Egyptian herbals. Seeds likely used for herbalism were found in archaeological sites of Bronze Age China dating from the Shang dynasty ( c.  1600  – c.  1046 BCE ). Over a hundred of the 224 compounds mentioned in the Huangdi Neijing , an early Chinese medical text, are herbs. Herbs were also commonly used in the traditional medicine of ancient India, where the principal treatment for diseases

12024-492: The European population remained rural peasants. Many were no longer settled in isolated farms but had gathered into small communities, usually known as manors or villages. These peasants were often subject to noble overlords and owed them rents and other services, in a system known as manorialism . There remained a few free peasants throughout this period and beyond, with more of them in the regions of Southern Europe than in

12191-733: The Frankish King Charles the Simple (r. 898–922) to settle in what became Normandy . The eastern parts of the Frankish kingdoms, especially Germany and Italy, were under continual Magyar assault until the invader's defeat at the Battle of Lechfeld in 955. The breakup of the Abbasid dynasty meant that the Islamic world fragmented into smaller political states, some of which began expanding into Italy and Sicily, as well as over

12358-578: The Franks and Celtic Britons set up small polities. Francia was centred in northern Gaul, and the first king of whom much is known is Childeric I (d. 481). His grave was discovered in 1653 and is remarkable for its grave goods , which included weapons and a large quantity of gold. Under Childeric's son Clovis I (r. 509–511), the founder of the Merovingian dynasty , the Frankish kingdom expanded and converted to Christianity. The Britons, related to

12525-685: The German tried to annex all of East Francia. Louis the Pious died in 840, with the empire still in chaos. A three-year civil war followed his death. By the Treaty of Verdun (843), a kingdom between the Rhine and Rhone rivers was created for Lothair to go with his lands in Italy, and his imperial title was recognised. Louis the German was in control of Bavaria and the eastern lands in modern-day Germany. Charles

12692-700: The Great (d. 526) and set up a kingdom marked by its co-operation between the Italians and the Ostrogoths, at least until the last years of Theodoric's reign. The Burgundians settled in Gaul, and after an earlier realm was destroyed by the Huns in 436, formed a new kingdom in the 440s. Between today's Geneva and Lyon , it grew to become the realm of Burgundy in the late 5th and early 6th centuries. Elsewhere in Gaul,

12859-560: The High Middle Ages. This period also saw the collapse of the unified Christian church, with the East-West Schism of 1054 . The Crusades , first preached in 1095, were military attempts by Western European Christians to regain control of the Holy Land from Muslims . Kings became the heads of centralised nation-states , reducing crime and violence but making the ideal of a unified Christendom more distant. Intellectual life

13026-516: The Italian peninsula was conquered by the Ostrogoths . The Eastern Roman Empire, often referred to as the Byzantine Empire after the fall of its western counterpart, had little ability to assert control over the lost western territories. The Byzantine emperors maintained a claim over the territory, but while none of the new kings in the west dared to elevate himself to the position of emperor of

13193-796: The Italian peninsula. From the 15th century to the 16th century, the apothecary gained the status of a skilled practitioner. In London, the apothecaries merited their own livery company , the Worshipful Society of Apothecaries , founded in 1617. Its roots, however, go back much earlier to the Guild of Pepperers formed in London in 1180. Similarly in Ireland, Apothecaries were organized since before 1446. In Ireland and Great Britain they were allowed to diagnose in addition to compounding and dispensing, becoming regulated general medical practitioners and

13360-748: The Late Middle Ages and beginning the early modern period . The Middle Ages is one of the three major periods in the most enduring scheme for analysing European history : classical civilisation or Antiquity , the Middle Ages and the Modern Period . The "Middle Ages" first appears in Latin in 1469 as media tempestas or "middle season". In early usage, there were many variants, including medium aevum , or "middle age", first recorded in 1604, and media saecula , or "middle centuries", first recorded in 1625. The adjective "medieval" (or sometimes "mediaeval" or "mediæval"), meaning pertaining to

13527-559: The Lombards, which freed the papacy from the fear of Lombard conquest and marked the beginnings of the Papal States . The coronation of Charlemagne as emperor on Christmas Day 800 is regarded as a turning point in medieval history, marking a return of the Western Roman Empire, since the new emperor ruled over much of the area previously controlled by the Western emperors. It also marks a change in Charlemagne's relationship with

13694-405: The Mediterranean, pottery remained prevalent and appears to have been traded over medium-range networks, not just produced locally. The various Germanic states in the west all had coinages that imitated existing Roman and Byzantine forms. Gold continued to be minted until the end of the 7th century in 693-94 when it was replaced by silver in the Merovingian kingdom. The basic Frankish silver coin

13861-411: The Middle Ages, derives from medium aevum . Medieval writers divided history into periods such as the " Six Ages " or the " Four Empires ", and considered their time to be the last before the end of the world. When referring to their own times, they spoke of them as being "modern". In the 1330s, the Italian humanist and poet Petrarch referred to pre-Christian times as antiqua (or "ancient") and to

14028-788: The Middle East than Europe, losing control of sections of the Muslim lands. Umayyad descendants took over the Iberian Peninsula, the Aghlabids controlled North Africa, and the Tulunids became rulers of Egypt. By the middle of the 8th century, new trading patterns were emerging in the Mediterranean; trade between the Franks and the Arabs replaced the old Roman economy . Franks traded timber, furs, swords and slaves in return for silks and other fabrics, spices, and precious metals from

14195-666: The Pyrenees into the southern parts of the Frankish kingdoms. Efforts by local kings to fight the invaders led to the formation of new political entities. In Anglo-Saxon England , King Alfred the Great (r. 871–899) came to an agreement with the Viking invaders in the late 9th century, resulting in Danish settlements in Northumbria, Mercia, and parts of East Anglia. By the middle of the 10th century, Alfred's successors had conquered Northumbria, and restored English control over most of

14362-623: The Rhine and eastwards, leaving Charles West Francia with the empire to the west of the Rhineland and the Alps. Louis the German (d. 876), the middle child, who had been rebellious to the last, was allowed to keep Bavaria under the suzerainty of his elder brother. The division was disputed. Pepin II of Aquitaine (d. after 864), the emperor's grandson, rebelled in a contest for Aquitaine , while Louis

14529-515: The Roman Empire into a more flexible form to fit the needs of the Church and government. By the reign of Charlemagne, the language had so diverged from the classical Latin that it was later called Medieval Latin . Charlemagne planned to continue the Frankish tradition of dividing his kingdom between all his heirs, but was unable to do so as only one son, Louis the Pious (r. 814–840), was still alive by 813. Just before Charlemagne died in 814, he crowned Louis as his successor. Louis's reign of 26 years

14696-496: The Romans and the invaders are often similar, and tribal items were often modelled on Roman objects. Much of the scholarly and written culture of the new kingdoms was also based on Roman intellectual traditions. An important difference was the gradual loss of tax revenue by the new polities. Many of the new political entities no longer supported their armies through taxes, instead relying on granting them land or rents. This meant there

14863-585: The Vandals went on to cross the strait of Gibraltar after which they conquered the province of Africa . In the 430s the Huns began invading the empire; their king Attila (r. 434–453) led invasions into the Balkans in 442 and 447, Gaul in 451, and Italy in 452. The Hunnic threat remained until Attila's death in 453, when the Hunnic confederation he led fell apart. These invasions by the tribes completely changed

15030-455: The West were not uniform; some areas had greatly fragmented landholding patterns, but in other areas large contiguous blocks of land were the norm. These differences allowed for a wide variety of peasant societies, some dominated by aristocratic landholders and others having a great deal of autonomy. Land settlement also varied greatly. Some peasants lived in large settlements that numbered as many as 700 inhabitants. Others lived in small groups of

15197-748: The Western Roman Empire and transitioned into the Renaissance and the Age of Discovery . The Middle Ages is the middle period of the three traditional divisions of Western history: classical antiquity , the medieval period, and the modern period . The medieval period is itself subdivided into the Early , High , and Late Middle Ages . Population decline , counterurbanisation , the collapse of centralized authority, invasions, and mass migrations of tribes , which had begun in Late Antiquity , continued into

15364-567: The acceptance of figurative monumental sculpture in Christian art , and by the end of the period near life-sized figures such as the Gero Cross were common in important churches. During the later Roman Empire, the principal military developments were attempts to create an effective cavalry force as well as the continued development of highly specialised types of troops. The creation of heavily armoured cataphract -type soldiers as cavalry

15531-417: The basilica is the use of a transept , or the "arms" of a cross-shaped building that are perpendicular to the long nave . Other new features of religious architecture include the crossing tower and a monumental entrance to the church , usually at the west end of the building. Carolingian art was produced for a small group of figures around the court, and the monasteries and churches they supported. It

15698-899: The belief that preserving various substances from a given source with less processing is safer or more effective than manufactured products, a concept for which there is no evidence. Archaeological evidence indicates that the use of medicinal plants dates back to the Paleolithic age, approximately 60,000 years ago. Written evidence of herbal remedies dates back over 5,000 years to the Sumerians , who compiled lists of plants. Some ancient cultures wrote about plants and their medical uses in books called herbals . In ancient Egypt, herbs were mentioned in Egyptian medical papyri , depicted in tomb illustrations, or on rare occasions found in medical jars containing trace amounts of herbs. In ancient Egypt,

15865-632: The break with classical antiquity was not complete. The still-sizeable Byzantine Empire, Rome's direct continuation, survived in the Eastern Mediterranean and remained a major power. The empire's law code, the Corpus Juris Civilis or "Code of Justinian", was rediscovered in Northern Italy in the 11th century. In the West, most kingdoms incorporated the few extant Roman institutions. Monasteries were founded as campaigns to Christianise pagan Europe continued. The Franks , under

16032-407: The city of Byzantium as the newly renamed eastern capital, Constantinople . Diocletian's reforms strengthened the governmental bureaucracy, reformed taxation, and strengthened the army, which bought the empire time but did not resolve the problems it was facing: excessive taxation, a declining birthrate, and pressures on its frontiers, among others. Civil war between rival emperors became common in

16199-599: The conquest of North Africa sundered maritime connections between those areas. Increasingly, the Byzantine Church differed in language, practices, and liturgy from the Western Church. The Eastern Church used Greek instead of the Western Latin. Theological and political differences emerged, and by the early and middle 8th century issues such as iconoclasm , clerical marriage , and state control of

16366-684: The construction of the Hagia Sophia in Constantinople and the reconquest of North Africa from the Vandals and Italy from the Ostrogoths, under Belisarius (d. 565). The conquest of Italy was not complete, as a deadly outbreak of plague in 542 led to the rest of Justinian's reign concentrating on defensive measures rather than further conquests. At the Emperor's death, the Byzantines had control of most of Italy , North Africa, and

16533-496: The control of kings. There were perhaps as many as 150 local kings in Ireland, of varying importance. The Carolingian dynasty , as the successors to Charles Martel are known, officially took control of the kingdoms of Austrasia and Neustria in a coup of 753 led by Pippin III (r. 752–768). A contemporary chronicle claims that Pippin sought, and gained, authority for this coup from Pope Stephen II (pope 752–757). Pippin's takeover

16700-409: The convents to solidify the sanctity of religion among their sisters. As they progressed in skill they started to expand their field to create profit. This profit they used towards their charitable goals. Because of their eventual spread to urban society, these religious women gained "roles of public significance beyond the spiritual realm (Strocchia 627). Later apothecaries led by nuns were spread across

16867-638: The conversion of the Moravians , Bulgars , Bohemians , Poles , Magyars, and Slavic inhabitants of the Kievan Rus' . These conversions contributed to the founding of political states in the lands of those peoples—the states of Moravia , Bulgaria , Bohemia , Poland , Hungary, and the Kievan Rus'. Bulgaria, which was founded around 680, at its height reached from Budapest to the Black Sea and from

17034-700: The death of Louis the Child , and the selection of the unrelated Conrad I (r. 911–918) as king. The breakup of the Carolingian Empire was accompanied by invasions, migrations, and raids by external foes. The Atlantic and northern shores were harassed by the Vikings , who also raided the British Isles and settled there as well as in Iceland. In 911, the Viking chieftain Rollo (d. c. 931) received permission from

17201-401: The death of Queen Isabella I of Castile in 1504, or the conquest of Granada in 1492. Historians from Romance-speaking countries tend to divide the Middle Ages into two parts: an earlier "High" and later "Low" period. English-speaking historians, following their German counterparts, generally subdivide the Middle Ages into three intervals: "Early", "High", and "Late". In the 19th century,

17368-578: The disorder, was killed fighting the Goths at the Battle of Adrianople on 9 August 378. In addition to the threat from such tribal confederacies in the north, internal divisions within the empire, especially within the Christian Church, caused problems. In 400, the Visigoths invaded the Western Roman Empire and, although briefly forced back from Italy, in 410 sacked the city of Rome . In 406

17535-442: The early Carolingian period, with a growing dominance of elite heavy cavalry. The use of militia-type levies of the free population declined over the Carolingian period. Although much of the Carolingian armies were mounted, a large proportion during the early period appear to have been mounted infantry , rather than true cavalry. One exception was Anglo-Saxon England, where the armies were still composed of regional levies, known as

17702-531: The elites was richly embellished with jewels and gold. Lords and kings supported entourages of fighters who formed the backbone of the military forces. Family ties within the elites were important, as were the virtues of loyalty, courage, and honour. These ties led to the prevalence of the feud in aristocratic society, examples of which included those related by Gregory of Tours that took place in Merovingian Gaul. Most feuds seem to have ended quickly with

17869-591: The emergence of Islam in Arabia during the lifetime of Muhammad (d. 632). After his death, Islamic forces conquered much of the Eastern Roman Empire and Persia, starting with Syria in 634–635, continuing with Persia between 637 and 642, reaching Egypt in 640–641, North Africa in the later seventh century, and the Iberian Peninsula in 711. By 714, Islamic forces controlled much of

18036-403: The empire than tax-payers. The Emperor Diocletian (r. 284–305) split the empire into separately administered eastern and western halves in 286; the empire was not considered divided by its inhabitants or rulers, as legal and administrative promulgations in one division were considered valid in the other. In 330, after a period of civil war, Constantine the Great (r. 306–337) refounded

18203-573: The empire to Christianity , a gradual process that lasted from the 2nd to the 5th centuries. In 376, the Goths , fleeing from the Huns , received permission from Emperor Valens (r. 364–378) to settle in the Roman province of Thracia in the Balkans . The settlement did not go smoothly, and when Roman officials mishandled the situation, the Goths began to raid and plunder. Valens, attempting to put down

18370-447: The empire, including Egypt, Syria, and Anatolia until Heraclius' successful counterattack. In 628 the empire secured a peace treaty and recovered all of its lost territories. In Western Europe, some of the older Roman elite families died out while others became more involved with ecclesiastical than secular affairs. Values attached to Latin scholarship and education mostly disappeared, and while literacy remained important, it became

18537-486: The empire. Such movements were aided by the refusal of the Western Roman elites to support the army or pay the taxes that would have allowed the military to suppress the migration. The emperors of the 5th century were often controlled by military strongmen such as Stilicho (d. 408), Aetius (d. 454), Aspar (d. 471), Ricimer (d. 472), or Gundobad (d. 516), who were partly or fully of non-Roman background. When

18704-454: The entire Middle Ages were often referred to as the " Dark Ages ", but with the adoption of these subdivisions, use of this term was restricted to the Early Middle Ages, at least among historians. The Roman Empire reached its greatest territorial extent during the 2nd century AD; the following two centuries witnessed the slow decline of Roman control over its outlying territories. Economic issues, including inflation, and external pressure on

18871-767: The first woman to be licensed to practice medicine in Britain by passing the examination of the Society of Apothecaries. By the end of the 19th century, the medical professions had taken on their current institutional form, with defined roles for physicians and surgeons, and the role of the apothecary was more narrowly conceived, as that of pharmacist (dispensing chemist in British English). In German-speaking countries, such as Germany, Austria and Switzerland, pharmacies or chemist stores are still called apothecaries or in German Apotheken . The Apotheke ("store")

19038-699: The forerunners of General Practitioners there. However, there were ongoing tensions between apothecaries and other medical professions, as is illustrated by the publication of 'A Short View of the Frauds and Abuses Committed by Apothecaries' by the Physician Christopher Merrett in 1669 and the experiences of Susan Reeve Lyon and other women apothecaries in 17th century London. Often women (who were prohibited from entering medical school) became apothecaries which took away business from male physicians. In 1865 Elizabeth Garrett Anderson became

19205-635: The frontiers combined to create the Crisis of the Third Century , with emperors coming to the throne only to be rapidly replaced by new usurpers. Military expenses increased steadily during the 3rd century, mainly in response to the war with the Sasanian Empire , which revived in the middle of the 3rd century. The army doubled in size, and cavalry and smaller units replaced the Roman legion as

19372-451: The imperial officials called missi dominici , who served as roving inspectors and troubleshooters. Charlemagne's court in Aachen was the centre of the cultural revival sometimes referred to as the " Carolingian Renaissance ". Literacy increased, as did development in the arts, architecture and jurisprudence, as well as liturgical and scriptural studies. The English monk Alcuin (d. 804)

19539-537: The investigation, with all but five containing DNA that did not match the product labels. In some countries, formalized training and minimum education standards exist for herbalists, although these are not necessarily uniform within or between countries. In Australia, for example, the self-regulated status of the profession (as of 2009) resulted in variable standards of training, and numerous loosely formed associations setting different educational standards. One 2009 review concluded that regulation of herbalists in Australia

19706-415: The king of the united Austrasia and Neustria. Charles, more often known as Charles the Great or Charlemagne , embarked upon a programme of systematic expansion in 774 that unified a large portion of Europe, eventually controlling modern-day France, northern Italy, and Saxony . In the wars that lasted beyond 800, he rewarded allies with war booty and command over parcels of land. In 774, Charlemagne conquered

19873-679: The large brooches in fibula or penannular form that were a key piece of personal adornment for elites, including the Irish Tara Brooch . Highly decorated books were mostly Gospel Books and these have survived in larger numbers , including the Insular Book of Kells , the Book of Lindisfarne , and the imperial Codex Aureus of St. Emmeram , which is one of the few to retain its " treasure binding " of gold encrusted with jewels. Charlemagne's court seems to have been responsible for

20040-476: The letters, of Pope Gregory the Great (pope 590–604) survived, and of those more than 850 letters, the vast majority were concerned with affairs in Italy or Constantinople. The only part of Western Europe where the papacy had influence was Britain, where Gregory had sent the Gregorian mission in 597 to convert the Anglo-Saxons to Christianity. Irish missionaries were most active in Western Europe between

20207-417: The line of Western emperors ceased, many of the kings who replaced them were from the same background. Intermarriage between the new kings and the Roman elites was common. This led to a fusion of Roman culture with the customs of the invading tribes, including the popular assemblies that allowed free male tribal members more say in political matters than was common in the Roman state. Material artefacts left by

20374-514: The long-term boiled extracts, usually of harder substances like roots or bark. Maceration is the cold infusion of plants with high mucilage -content, such as sage or thyme . To make macerates, plants are chopped and added to cold water. They are then left to stand for 7 to 12 hours (depending on the herb used). For most macerates, 10 hours is used. Tinctures are alcoholic extracts of herbs, which are generally stronger than herbal teas. Tinctures are usually obtained by combining pure ethanol (or

20541-517: The main and sometimes only outposts of education and literacy in a region. Many of the surviving manuscripts of the Latin classics were copied in monasteries in the Early Middle Ages. Monks were also the authors of new works, including history, theology, and other subjects, written by authors such as Bede (d. 735), a native of northern England who wrote in the late 7th and early 8th centuries. The Frankish kingdom in northern Gaul split into kingdoms called Austrasia , Neustria , and Burgundy during

20708-410: The main tactical unit. The need for revenue led to increased taxes and a decline in numbers of the curial , or landowning, class, and decreasing numbers of them willing to shoulder the burdens of holding office in their native towns. More bureaucrats were needed in the central administration to deal with the needs of the army, which led to complaints from civilians that there were more tax-collectors in

20875-615: The medicines they prepared wholesale to other medical practitioners, as well as dispensing them to patients. In 17th-century England, they also controlled the trade in tobacco which was imported as a medicine. The term "apothecary" derives from the Ancient Greek ἀποθήκη ( apothḗkē , "a repository, storehouse") via Latin apotheca ("repository, storehouse, warehouse", cf. bodega and boutique ), Medieval Latin apothecarius ("storekeeper"), and eventually Old French apotecaire . In some European and other languages,

21042-401: The middle of the 4th century, diverting soldiers from the empire's frontier forces and allowing invaders to encroach. For much of the 4th century, Roman society stabilised in a new form that differed from the earlier classical period , with a widening gulf between the rich and poor, and a decline in the vitality of the smaller towns. Another change was the Christianisation , or conversion of

21209-436: The migrations of the Slavs added Slavic languages to Eastern Europe. As Western Europe witnessed the formation of new kingdoms, the Eastern Roman Empire remained intact and experienced an economic revival that lasted into the early 7th century. There were fewer invasions of the eastern section of the empire; most occurred in the Balkans. Peace with the Sasanian Empire , the traditional enemy of Rome, lasted throughout most of

21376-464: The military was the horseshoe , which allowed horses to be used in rocky terrain. The High Middle Ages was a period of tremendous expansion of population . The estimated population of Europe grew from 35 to 80 million between 1000 and 1347, although the exact causes remain unclear: improved agricultural techniques, the decline of slaveholding, a more clement climate and the lack of invasion have all been suggested. As much as 90 per cent of

21543-429: The natives of Britannia  – modern-day Great Britain – settled in what is now Brittany . Other monarchies were established by the Visigothic Kingdom in the Iberian Peninsula , the Suebi in northwestern Iberia, and the Vandal Kingdom in North Africa . In the sixth century, the Lombards settled in Northern Italy , replacing the Ostrogothic kingdom with a grouping of duchies that occasionally selected

21710-462: The other hand is a non-polar solvent and it will absorb non-polar compounds. Alcohol lies somewhere in between. Many herbs are applied topically to the skin in a variety of forms. Essential oil extracts can be applied to the skin, usually diluted in a carrier oil. Many essential oils can burn the skin or are simply too high dose used straight; diluting them in olive oil or another food grade oil such as almond oil can allow these to be used safely as

21877-414: The past such as urine, fecal matter, earwax, human fat, and saliva, are no longer used and are generally considered ineffective or unsanitary. Trial and error were the main source for finding successful remedies, as little was known about the chemistry of why certain treatments worked. For instance, it was known that drinking coffee could help cure headaches, but the existence and properties of caffeine itself

22044-478: The payment of some sort of compensation . Women took part in aristocratic society mainly in their roles as wives and mothers of men, with the role of mother of a ruler being especially prominent in Merovingian Gaul. In Anglo-Saxon society the lack of many child rulers meant a lesser role for women as queen mothers, but this was compensated for by the increased role played by abbesses of monasteries. Only in Italy does it appear that women were always considered under

22211-467: The peninsula in a region they called Al-Andalus . The Islamic conquests reached their peak in the mid-eighth century. The defeat of Muslim forces at the Battle of Tours in 732 led to the reconquest of southern France by the Franks, but the main reason for the halt of Islamic growth in Europe was the overthrow of the Umayyad Caliphate and its replacement by the Abbasid Caliphate . The Abbasids moved their capital to Baghdad and were more concerned with

22378-408: The political and demographic nature of what had been the Western Roman Empire. By the end of the 5th century the western section of the empire was divided into smaller political units, ruled by the tribes that had invaded in the early part of the century. The deposition of the last emperor of the west, Romulus Augustulus , in 476 has traditionally marked the end of the Western Roman Empire. By 493

22545-532: The political power devolved to the local lords. Missionary efforts to Scandinavia during the 9th and 10th centuries helped strengthen the growth of kingdoms such as Sweden , Denmark , and Norway , which gained power and territory. Some kings converted to Christianity, although not all by 1000. Scandinavians also expanded and colonised throughout Europe. Besides the settlements in Ireland, England, and Normandy, further settlement took place in what became Russia and Iceland . Swedish traders and raiders ranged down

22712-750: The potential for misleading health advice. Globally, there are no standards across various herbal products to authenticate their contents, safety or efficacy, and there is generally an absence of high-quality scientific research on product composition or effectiveness for anti-disease activity. Presumed claims of therapeutic benefit from herbal products, without rigorous evidence of efficacy and safety, receive skeptical views by scientists. Unethical practices by some herbalists and manufacturers, which may include false advertising about health benefits on product labels or literature, and contamination or use of fillers during product preparation, may erode consumer confidence about services and products. Paraherbalism

22879-505: The practitioners of this medical system. The Indian book, Vedas, mentions treatment of diseases with plants. In Indonesia , especially among the Javanese , the jamu traditional herbal medicine may have originated in the Mataram Kingdom era, some 1300 years ago. The bas-reliefs on Borobudur depict the image of people grinding herbs with stone mortar and pestle , a drink seller, a herbalist, and masseuse treating people. The Madhawapura inscription from Majapahit period mentioned

23046-443: The prevalence of herbal remedy use. There are many forms in which herbs can be administered, the most common of which is a liquid consumed as a herbal tea or a (possibly diluted) plant extract. Herbal teas , or tisanes, are the resultant liquid of extracting herbs into water, though they are made in a few different ways. Infusions are hot water extracts of herbs, such as chamomile or mint , through steeping . Decoctions are

23213-419: The protection and control of a male relative. Peasant society is much less documented than the nobility. Most of the surviving information available to historians comes from archaeology ; few detailed written records documenting peasant life remain from before the 9th century. Most of the descriptions of the lower classes come from either law codes or writers from the upper classes. Landholding patterns in

23380-470: The rivers of the Russian steppe, and even attempted to seize Constantinople in 860 and 907 . Christian Spain, initially driven into a small section of the peninsula in the north, expanded slowly south during the 9th and 10th centuries, establishing the kingdoms of Asturias and León . In Eastern Europe, Byzantium revived its fortunes under Emperor Basil I (r. 867–886) and his successors Leo VI (r. 886–912) and Constantine VII (r. 913–959), members of

23547-438: The safety and efficacy of each plant before medical use. Although many consumers believe that herbal medicines are safe because they are natural, herbal medicines and synthetic drugs may interact, causing toxicity to the consumer. Herbal remedies can also be dangerously contaminated, and herbal medicines without established efficacy, may unknowingly be used to replace prescription medicines. Standardization of purity and dosage

23714-408: The safety and efficacy of herbal products, the European Medicines Agency provided criteria in 2017 for evaluating and grading the quality of clinical research in preparing monographs about herbal products. In the United States, the National Center for Complementary and Integrative Health of the National Institutes of Health funds clinical trials on herbal compounds, provides fact sheets evaluating

23881-593: The safety, potential effectiveness and side effects of many plant sources, and maintains a registry of clinical research conducted on herbal products. According to Cancer Research UK as of 2015, "there is currently no strong evidence from studies in people that herbal remedies can treat, prevent or cure cancer". The use of herbal remedies is more prevalent in people with chronic diseases , such as cancer, diabetes , asthma , and end-stage kidney disease . Multiple factors such as gender, age, ethnicity, education and social class are also shown to have associations with

24048-449: The slow infiltration of the Balkans by the Slavs added a further difficulty for Justinian's successors. It began gradually, but by the late 540s Slavic tribes were in Thrace and Illyrium , and had defeated an imperial army near Adrianople in 551. In the 560s the Avars began to expand from their base on the north bank of the Danube ; by the end of the 6th-century, they were the dominant power in Central Europe and routinely able to force

24215-430: The southern part of Great Britain. In northern Britain, Kenneth MacAlpin (d. c. 860) united the Picts and the Scots into the Kingdom of Alba . In the early 10th century, the Ottonian dynasty had established itself in Germany , and was engaged in driving back the Magyars. Its efforts culminated in the coronation in 962 of Otto I (r. 936–973) as Holy Roman Emperor . In 972, he secured recognition of his title by

24382-428: The specialized agency of the United Nations (UN) that is concerned with international public health, published Quality control methods for medicinal plant materials in 1998 to support WHO Member States in establishing quality standards and specifications for herbal materials, within the overall context of quality assurance and control of herbal medicines. In the European Union (EU), herbal medicines are regulated under

24549-609: The term is current and used to designate a pharmacist/chemist, such as Dutch and German Apotheker , Hungarian patikus , Irish poitigéir , Latvian aptiekārs and Luxembourgish Apdikter . Likewise, "pharmacy" translates as apotek in Danish , Norwegian and Swedish , apteekki in Finnish , apoteka in Bosnian , patika in Hungarian, aptieka in Latvian , апотека ( apoteka ) in Serbian , аптека ( apteka ) in Russian , Bulgarian , Macedonian and Ukrainian , Apotheke in German and apteka in Polish . The word in Indonesian

24716-447: The towns chosen as capitals. Although there had been Jewish communities in many Roman cities , the Jews suffered periods of persecution after the conversion of the empire to Christianity. Officially they were tolerated, if subject to conversion efforts, and at times were even encouraged to settle in new areas. Religious beliefs in the Eastern Roman Empire and Iran were in flux during the late sixth and early seventh centuries. Judaism

24883-918: The trade themselves. Women were still not allowed to train and be educated in universities so this allowed them a chance to be trained in medical knowledge and healing. Previously, women had some influence in other women's healthcare, such as serving as midwives and other feminine care in a setting that was not considered appropriate for males. Though physicians gave medical advice, they did not make medicine, so they typically sent their patients to particular independent apothecaries, who did also provide some medical advice, in particular remedies and healing. Many recipes for medicines included herbs, minerals, and pieces of animals (meats, fats, skins) that were ingested, made into paste for external use, or used as aromatherapy. Some of these are similar to natural remedies used today, including catnip , chamomile , fennel , mint , garlic , and witch hazel . Many other ingredients used in

25050-454: The use of entheogens , in particular the San Pedro cactus ( Echinopsis pachanoi ) is still a vital component, and has been around for millennia. Some researchers trained in both Western and traditional Chinese medicine have attempted to deconstruct ancient medical texts in the light of modern science. In 1972, Tu Youyou , a pharmaceutical chemist and Nobel Prize winner , extracted the anti-malarial drug artemisinin from sweet wormwood ,

25217-514: The west, Byzantine control of most of the Western Empire could not be sustained; the reconquest of the Mediterranean periphery and the Italian Peninsula ( Gothic War ) in the reign of Justinian (r. 527–565) was the sole, and temporary, exception. The political structure of Western Europe changed with the end of the united Roman Empire. Although the movements of peoples during this period are usually described as "invasions", they were not just military expeditions but migrations of entire peoples into

25384-438: Was a trend throughout the old Roman lands that happened in the Early Middle Ages. This was especially marked in the lands that did not lie on the Mediterranean, such as northern Gaul or Britain. Non-local goods appearing in the archaeological record are usually luxury goods. In the northern parts of Europe, not only were the trade networks local, but the goods carried were simple, with little pottery or other complex products. Around

25551-402: Was an active proselytising faith, and at least one Arab political leader converted to it. In addition Jewish theologians wrote polemics defending their religion against Christian and Islamic influences. Christianity had active missions competing with the Persians' Zoroastrianism in seeking converts, especially among residents of the Arabian Peninsula . All these strands came together with

25718-438: Was an important feature of the 5th-century Roman military. The various invading tribes had differing emphases on types of soldiers—ranging from the primarily infantry Anglo-Saxon invaders of Britain to the Vandals and Visigoths who had a high proportion of cavalry in their armies. During the early invasion period, the stirrup had not been introduced into warfare, which limited the usefulness of cavalry as shock troops because it

25885-478: Was diet. De Materia Medica , originally written in Greek by Pedanius Dioscorides ( c.  40  – c.  90 CE ) of Anazarbus , Cilicia , a physician and botanist, is one example of herbal writing used over centuries until the 1600s. The World Health Organization (WHO) estimates that 80 percent of the population of some Asian and African countries presently uses herbal medicine for some aspect of primary health care. Some prescription drugs have

26052-420: Was dominated by efforts to regain the dignity and classicism of imperial Roman and Byzantine art , but was also influenced by the Insular art of the British Isles. Insular art integrated the energy of Irish Celtic and Anglo-Saxon Germanic styles of ornament with Mediterranean forms such as the book, and established many characteristics of art for the rest of the medieval period. Surviving religious works from

26219-408: Was invited to Aachen and brought the education available in the monasteries of Northumbria. Charlemagne's chancery —or writing office—made use of a new script today known as Carolingian minuscule , allowing a common writing style that advanced communication across much of Europe. Charlemagne sponsored changes in church liturgy , imposing the Roman form of church service on his domains, as well as

26386-434: Was less need for large tax revenues and so the taxation systems decayed. Warfare was common between and within the kingdoms. Slavery declined as the supply weakened, and society became more rural. Between the 5th and 8th centuries, new peoples and individuals filled the political void left by Roman centralised government. The Ostrogoths , a Gothic tribe, settled in Roman Italy in the late fifth century under Theoderic

26553-436: Was marked by scholasticism , a philosophy that emphasised joining faith to reason, and by the founding of universities . The theology of Thomas Aquinas , the paintings of Giotto , the poetry of Dante and Chaucer , the travels of Marco Polo , and the Gothic architecture of cathedrals such as Chartres are among the outstanding achievements toward the end of this period and into the Late Middle Ages. The Late Middle Ages

26720-470: Was marked by difficulties and calamities including famine, plague, and war, which significantly diminished the population of Europe; between 1347 and 1350, the Black Death killed about a third of Europeans. Controversy, heresy , and the Western Schism within the Catholic Church paralleled the interstate conflict, civil strife, and peasant revolts that occurred in the kingdoms. Cultural and technological developments transformed European society, concluding

26887-439: Was marked by numerous divisions of the empire among his sons and, after 829, civil wars between various alliances of father and sons over the control of various parts of the empire. Eventually, Louis recognised his eldest son Lothair I (d. 855) as emperor and gave him Italy. Louis divided the rest of the empire between Lothair and Charles the Bald (d. 877), his youngest son. Lothair took East Francia , comprising both banks of

27054-416: Was needed to reduce the risk of interaction of herbal medicines with prescription drugs , to implement clinical guidelines and prescription of herbal products, and to assure self-regulation for protection of public health and safety. In the United Kingdom, the training of herbalists is done by state-funded universities offering Bachelor of Science degrees in herbal medicine. In the United States, according to

27221-496: Was not possible to put the full force of the horse and rider behind blows struck by the rider. The greatest change in military affairs during the invasion period was the adoption of the Hunnic composite bow in place of the earlier, and weaker, Scythian composite bow. Another development was the increasing use of longswords and the progressive replacement of scale armour by mail armour and lamellar armour . The importance of infantry and light cavalry began to decline during

27388-442: Was reinforced with propaganda that portrayed the Merovingians as inept or cruel rulers, exalted the accomplishments of Charles Martel, and circulated stories of the family's great piety. At the time of his death in 768, Pippin left his kingdom in the hands of his two sons, Charles (r. 768–814) and Carloman (r. 768–771). When Carloman died of natural causes, Charles blocked the succession of Carloman's young son and installed himself as

27555-441: Was still a mystery. Herbalism Herbal medicine (also called herbalism , phytomedicine or phytotherapy ) is the study of pharmacognosy and the use of medicinal plants , which are a basis of traditional medicine . With worldwide research into pharmacology , some herbal medicines have been translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from Artemisia annua ,

27722-417: Was the denarius or denier , while the Anglo-Saxon version was called a penny . From these areas, the denier or penny spread throughout Europe from 700 to 1000 AD. Copper or bronze coins were not struck, nor were gold except in Southern Europe. No silver coins denominated in multiple units were minted. Christianity was a major unifying factor between Eastern and Western Europe before the Arab conquests, but

27889-409: Was with the British Isles and Scandinavia, in contrast to the older Roman Empire with its trading networks centred on the Mediterranean. The empire was administered by an itinerant court that travelled with the emperor, as well as approximately 300 imperial officials called counts , who administered the counties the empire had been divided into. Clergy and local bishops served as officials, as well as

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